So what exactly is glycation? It largely takes place
Speaker:when sugars such as glucose and fructose form non-enzymatic
Speaker:bonds with nucleic acids, proteins and lipids. They
Speaker:cross-link and then produce what is called glycotoxins. Here
Speaker:are some things you can do to help slow down glycation. Increasing
Speaker:your water intake helps to increase the body's ability to
Speaker:produce collagen and elastin. If you supplement your diet with
Speaker:vitamin B1 and B6 as AGE inhibitors,
Speaker:thiamine is a powerful antioxidant and will help fight free
Speaker:radicals. When AGE receptors accumulate a
Speaker:significant amount of AGEs or ages over
Speaker:time, it can result in... Welcome to the Holistic Skin Guru, where
Speaker:what's on the surface is just as important as what's underneath.
Speaker:I'm your host, Aamena. Let's dive deep into the world
Speaker:of holistic skincare. Hi
Speaker:everyone and welcome back. Sugar is not your friend. It's
Speaker:a silent killer. We always talk about diet, but how many
Speaker:people are paying attention to the sugar they consume
Speaker:and the impact that it's having on your skin? Sugar
Speaker:sag or glycation is a real thing. Prevention is
Speaker:better than cure. A diet high in sugar can cause the
Speaker:skin to droop, dull the appearance, and is termed gligation
Speaker:face. Sugar damages the collagen in the skin. Most of
Speaker:the time, we consume sugar in foods without even knowing it.
Speaker:So we need to control the levels of sugar in our diet. So
Speaker:what exactly is glycation? It largely takes place when
Speaker:sugars such as glucose and fructose form non-enzymatic bonds
Speaker:with nucleic acids, proteins, and lipids. They
Speaker:cross-link and then produce what is called glycotoxins, which
Speaker:are advanced glycation and the end product of
Speaker:that is AGES, A-G-E-S. Now the
Speaker:telltale signs are cobblestone or crosshatch
Speaker:lines above the lip and below the lip, discoloration or
Speaker:hyperpigmentation marks on your skin, deep lines in
Speaker:the nasolabial folds, or even the chin line. You'll
Speaker:see like a diagonal line that goes across the chin. That is
Speaker:a sign of glycation. When your jowls start to sag down and
Speaker:it's starting from the midface, you have that one line
Speaker:crease in the chin. These are all signs that glycation is
Speaker:taking place in the skin. When AGE receptors accumulate a
Speaker:significant amount of AGEs or ages over
Speaker:time, it can result in tissue damage, vascular
Speaker:endothelial cell damage in your blood cells and
Speaker:inflammation in vital organs such as your lungs or
Speaker:your kidneys. So how does glycation affect your skin?
Speaker:So we already know that we need a good amount of collagen in our skin,
Speaker:which maintains the skin's smoothness and elasticity. During
Speaker:the glycation process, the glucose fructose from
Speaker:the sugars link to the amino acids in your skin's two
Speaker:major proteins. These are collagen and
Speaker:elastin. The cross-linking then produces AGES,
Speaker:or A-G-E-S, and the glycation occurs. The
Speaker:damage from the glycation process on collagen-elastin fibers
Speaker:in your skin cannot be reversed and cannot be
Speaker:repaired, resulting in sagging and wrinkled skin.
Speaker:So this is very important. Pay attention. Moreover, non-enzymatic
Speaker:glycation can induce oxidative stress, which
Speaker:is an imbalance of cell damaging free radicals and
Speaker:the antioxidants that can fight them off. This can lead to
Speaker:further cell damage in the form of lipid
Speaker:and free radical damage. In one recent study, they found
Speaker:that strictly controlling sugar levels over a four-month period
Speaker:resulted in a 25% reduction in glycation. So
Speaker:think about your sugar intake in your diet and how you
Speaker:can prevent the onset of glycation. The bad news is
Speaker:once it starts, we cannot reverse it, but we can start
Speaker:to turn things around. Start thinking about encouraging collagen
Speaker:production in your skin, and of course, cut out the sugars from
Speaker:your diet. The good news is that we can produce more collagen
Speaker:and elastin by boosting our fibroblast in the
Speaker:skin using devices like LED therapy or
Speaker:by collagen banking and doing such treatments such as SQT
Speaker:biomicroneedling or Haifu, which both stimulate
Speaker:collagen production deep in the skin. So keep
Speaker:away from excess sugar because they create collagen damaging
Speaker:molecules. Part of aging is glycation, but
Speaker:we need to keep in mind the rate at which it occurs. When
Speaker:we want to boost the collagen, we need to be able to heal
Speaker:well. So if our blood sugar rises, our
Speaker:skin ages or A-G-E-S are sticky and
Speaker:cross-link the collagen fibers, which ultimately weaken
Speaker:our collagen. This is what we call sugar sag. It
Speaker:will usually show in about age 35 to 40. So
Speaker:what does this mean for you? Start thinking about what
Speaker:you are consuming on a daily basis. If
Speaker:we can bring our sugar intake down to about 10% of
Speaker:our daily calorie intake. This is a recommendation from the World
Speaker:Health Organization, which is the biggest health organization in
Speaker:the world. We want to keep away from hidden sugars like those
Speaker:in pastas, salad dressings, sauces,
Speaker:sports drinks, cereals, juices, yogurts,
Speaker:which can put you over your daily sugar limit. Even our milk
Speaker:contains added sugar and we don't even think about it. So look
Speaker:at all the ingredients and know what you are consuming so that you can control
Speaker:the levels of sugar that you are ingesting. Now here are some things
Speaker:you can do to help slow down glycation. Increasing your water
Speaker:intake helps to increase the body's ability to produce collagen
Speaker:and elastin. If you supplement your diet with vitamin B1 and
Speaker:B6 as AGE inhibitors, thiamine is
Speaker:a powerful antioxidant and will help fight free radicals. Vitamin
Speaker:C on the skin is a natural antioxidant and
Speaker:it helps to strengthen the skin. So load up on
Speaker:antioxidants. They neutralize and protect the body from
Speaker:free radicals. This is how we can fight glycation or
Speaker:the early onset of glycation. Vitamin C
Speaker:is preferable, and we want one that is plant-based, not
Speaker:synthetic. Make sure it is plant-based because this is
Speaker:gonna be your long-term friend. The next thing you can
Speaker:do is get enough sleep. Sleep is incredibly great
Speaker:for your beauty routine because your skin rejuvenates while
Speaker:you are sleeping and will start to produce elastin and
Speaker:collagen in a more quality state of
Speaker:sleep. Melatonin is great to take to help you to go
Speaker:to sleep in a natural way, and it gets your sleep quality up.
Speaker:You can't overdose on melatonin. You can find natural melatonin
Speaker:in health food stores or pharmacies, and that's the one
Speaker:that I would steer you towards. Collagen peptides taken through
Speaker:supplements will increase your own collagen production. This
Speaker:is not speculation. This is a fact. There are a
Speaker:number of studies on this, so we know that we can see
Speaker:results with it. Lastly, protect your skin from harmful UV
Speaker:rays. UVA supercharges the glycation effect
Speaker:in the skin, so sugar and sun will destroy your
Speaker:skin the fastest. Before you come at me about sunscreens causing
Speaker:cancer, please check out my other video on sunscreens and
Speaker:what you need to know about them. The damage from the glycation process
Speaker:on collagen and elastin fibers can neither be reversed nor
Speaker:repaired, resulting in sagging and wrinkled skin.
Speaker:Did you know that sugar could affect your skin in this way? I'm
Speaker:interested to know if you've ever experienced anything that you
Speaker:think may be glycation. Leave the comments below. Thank
Speaker:you for joining me on Holistic Skin Guru. If this episode
Speaker:has helped you get one step closer to achieving your skin
Speaker:goals, I'd love your support with a five-star review
Speaker:on Apple Podcasts and Spotify. And don't forget
Speaker:to subscribe on your favorite platform too. If you've
Speaker:got any questions about your skin, I'd love to hear from
Speaker:you. Connect with me at Holistic Skin Guru on
Speaker:all platforms. Don't forget, as a listener, you can get 10% off
Speaker:all treatments at our SkinFit New Farm Clinic in
Speaker:Brisbane. Simply pop the word podcast in
Speaker:your booking online or mention it on the phone when