Jacob Shapiro:

Hello listeners.

Jacob Shapiro:

Welcome to another episode of the Jacob Shapiro podcast.

Jacob Shapiro:

Rob and I are back at it for our biweekly chats.

Jacob Shapiro:

Uh, we talk about things happening in the US market and honestly, we, uh,

Jacob Shapiro:

we were pretty, pretty glum today.

Jacob Shapiro:

We talked about Chinese biotech and bear cases for the United

Jacob Shapiro:

States and some disturbing cultural changes, uh, in the United States.

Jacob Shapiro:

Anyway, so we promise we'll be more upbeat next time, but, uh, this is definitely

Jacob Shapiro:

indulging in some more dystopian thoughts, so we hope you enjoy it.

Jacob Shapiro:

Email me, uh, jacob@jacobspi.com.

Jacob Shapiro:

If you have any questions, comments, concerns, you know the drill.

Jacob Shapiro:

Cheers and see you out there.

Jacob Shapiro:

All right.

Jacob Shapiro:

It is Wednesday, May 21st.

Jacob Shapiro:

Rob, it's been a minute since we got together.

Jacob Shapiro:

Uh, we're on our every other week cadence.

Jacob Shapiro:

Um, I don't know if you feel this way, and by saying this,

Jacob Shapiro:

maybe I'm gonna jinx ourselves.

Jacob Shapiro:

I feel like the last couple of weeks, the world has been a little bit quieter.

Jacob Shapiro:

Do, do you have that sense or am I just, uh, have I just gotten numb

Jacob Shapiro:

to the, the pace of volatility and events that we're experiencing?

Rob Larity:

Well, compared to what came before, I certainly hope so.

Rob Larity:

Otherwise, we'd all have a heart attack.

Jacob Shapiro:

No, it, it, it feel, I mean, it, it sort of feels like

Jacob Shapiro:

there was liberation day and then there was like a swell of volatility.

Jacob Shapiro:

And then the Trump administration met constraints head on in the form of

Jacob Shapiro:

treasury yields and a declining dollar.

Jacob Shapiro:

And, uh, you know, Scott Besson getting the president's ear and I, I won't

Jacob Shapiro:

say that things have been stable since then, but, you know, walked back from

Jacob Shapiro:

the biggest tariff threats like sort of normal level market discourse rather

Jacob Shapiro:

than, you know, what we were talking about even six weeks ago, like six weeks ago.

Jacob Shapiro:

I was having people like Chase on the podcast, you know, talking about is,

Jacob Shapiro:

are there great depression scenarios that we need to be worrying about?

Jacob Shapiro:

And now it's like we're talking about, oh, like we've got a big beautiful

Jacob Shapiro:

budget bill, which, uh, is gonna, I had the numbers in front of me here, uh,

Jacob Shapiro:

how much it might increase the deficit.

Jacob Shapiro:

Um.

Jacob Shapiro:

White House Council of Economic Advisors projects that the bill would boost GDP by

Jacob Shapiro:

4.2 to 5.2%, but, um, sort of independent budget analysis, if you're talking

Jacob Shapiro:

about the Joint Committee on taxation projects, they think it increases the

Jacob Shapiro:

deficit by 3.8 trillion through 2034.

Jacob Shapiro:

Penn Wharton budget model calls for a $3.3 trillion increase.

Jacob Shapiro:

Uh, Moody's is expecting a $4 trillion increase over the next decade and

Jacob Shapiro:

downgraded US credit ratings last Friday.

Jacob Shapiro:

Um.

Jacob Shapiro:

Markets.

Jacob Shapiro:

Markets are not particularly, uh, I don't know what the word is, sanguine,

Jacob Shapiro:

optimistic treasury yields are going up again, dollar index going down

Jacob Shapiro:

again relative to where we were.

Jacob Shapiro:

Um, so why, why don't we start with the US itself and with the bill?

Jacob Shapiro:

Because we've gone from, you know, Elon Musk at Center Stage and

Jacob Shapiro:

fiscal conservatism and Liberation Day two actually, like we're

Jacob Shapiro:

negotiating on all the tariffs and there's no fiscal conservatism.

Jacob Shapiro:

And Elon Musk has been put out to pasture and is talking about not donating

Jacob Shapiro:

money to political causes anymore.

Jacob Shapiro:

Um, so it, sure, it sure feels like constraints got here and now it's gonna

Jacob Shapiro:

be more normal trade policy and profligate deficit spending, which is pretty

Jacob Shapiro:

much on brand for every US government.

Jacob Shapiro:

Going back to Eisenhower, um, do you think that's the right way to assess the lay

Jacob Shapiro:

of the land or am I being too reductive?

Rob Larity:

Um, I think it is.

Rob Larity:

Uh, I mean, it's funny how these things work because like we often

Rob Larity:

talk about things being overbought or oversold when we talk about markets.

Rob Larity:

You can really feel that in the narrative, like what you said about

Rob Larity:

things quieting down, like that is expressed in charts too, where like

Rob Larity:

now we're clearing the hyperventilating levels of a few weeks ago.

Rob Larity:

Constraints are kicking in, they're dialing down the temperature.

Rob Larity:

Um, so yeah, I think there's, there's definitely an element of this, but

Rob Larity:

also sticking with that sort of charts, uh, comparison, the uptrend

Rob Larity:

remains intact, as we would say.

Rob Larity:

So a lot of these fundamental things that you talk about, um,

Rob Larity:

fiscal deficits blowing out, uh, all of that is continuing.

Rob Larity:

'cause that's the path of least resistance.

Rob Larity:

Um, so there may be constraints around doing things quickly or doing things in

Rob Larity:

an extreme way, but the path of least resistance is still holding for now.

Rob Larity:

Um, and you can see that in the price of the dollar.

Rob Larity:

You can see it in yields like, we've had a, a rebound in risk assets.

Rob Larity:

Basically clearing the oversold levels.

Rob Larity:

Like now we're back to a level where I would expect to

Rob Larity:

start seeing declines again.

Rob Larity:

Um, honestly.

Rob Larity:

So we will see if that happens.

Rob Larity:

But um, yeah, it's definitely sort of a, a, a calm within the storm moment.

Rob Larity:

And it's, it's funny that you mentioned scent, 'cause I've been reading this

Rob Larity:

biography of Zoe Unla, who's the, uh, was the right hand man of, of Mao

Rob Larity:

and this is sort of the unauthorized biography that was written by, uh, a

Rob Larity:

member of the inner circle of the CCP.

Rob Larity:

It was banned in China when it came out in like 2000.

Rob Larity:

But I was thinking about Bessant because much like Zoe and Lai, he bessant

Rob Larity:

has to be sort of a, a, a calming and moderating force within an egomaniac,

Rob Larity:

uh, you know, sort of dictating policies, not necessarily based on, uh.

Rob Larity:

Rational thought.

Rob Larity:

So it's a, it's a tough position to be in.

Jacob Shapiro:

It is, uh, I mean, Joe and LA is like maybe one of the most

Jacob Shapiro:

remarkable statesmen of the 20th century.

Jacob Shapiro:

Um, I, I wouldn't put him in the same category as Scott Best.

Jacob Shapiro:

I think like, like Joe and LA is like orders of magnitude or

Jacob Shapiro:

like standards of deviation.

Jacob Shapiro:

Uh, standards of deviation is more impressive to me as, as

Jacob Shapiro:

a statesman than Scott Besant.

Jacob Shapiro:

But May, but maybe I'm selling Scott Besant.

Jacob Shapiro:

Um, too short.

Jacob Shapiro:

I don't know.

Jacob Shapiro:

Um, we'll see

Rob Larity:

if he rises to the occasion.

Jacob Shapiro:

Yeah.

Jacob Shapiro:

And if, and if Maoism is, is what is on, uh, on tap for, uh, for the US government.

Jacob Shapiro:

Um, h how are, how are you digesting this budget?

Jacob Shapiro:

Bill and I, I know like it's, it's still not completely through.

Jacob Shapiro:

Um, it looks like it's probably gonna get through, but I mean, you know,

Jacob Shapiro:

you, you look at budget specialists and people who analyze the budget,

Jacob Shapiro:

literally that's all they do for a living.

Jacob Shapiro:

You know, here's one from the conservative Manhattan in institute.

Jacob Shapiro:

So the Manhattan Institute actually knew some people who used to work there.

Jacob Shapiro:

I don't think there are anymore.

Jacob Shapiro:

But, you know, generally fiscal conservatives or sort of

Jacob Shapiro:

typical small c conservatives.

Jacob Shapiro:

Um, and one of their budget specialists said, you know, this tax bill will

Jacob Shapiro:

cost more than the 27 tax cuts more than the pandemic cares act,

Jacob Shapiro:

more than Biden stimulus and the inflation reduction Act combined.

Jacob Shapiro:

Um, so like when you start to put that together, like, does that just

Jacob Shapiro:

mean we're gonna juice the economy and things are gonna be like.

Jacob Shapiro:

Pedal to the metal for the United States in terms of growth, but you

Jacob Shapiro:

know, we're just creating that much bigger of a bug that's gonna splash

Jacob Shapiro:

into the windshield down the road.

Jacob Shapiro:

I'm also really struck at the sort of inverse, not inverse,

Jacob Shapiro:

like the opposite way that China seems to be approaching this.

Jacob Shapiro:

Because for, you know, if you, the thing with China, if, if you read the tea

Jacob Shapiro:

leaves, there's always some interest rate that's being cut or some way that

Jacob Shapiro:

they're trying to stimulate the economy.

Jacob Shapiro:

But I was looking at, um, Shanghai macro strategist, he's one of my favorite

Jacob Shapiro:

follows on X and he was talking about how it seems like Beijing is actually doubling

Jacob Shapiro:

down on its commitment to austerity.

Jacob Shapiro:

Like talking about, you know, different initiatives to take the lead in

Jacob Shapiro:

living frugal lives for normal people on banning trips and re revising

Jacob Shapiro:

regulations for party officials.

Jacob Shapiro:

Um, you know, all these different things that might actually increase deflationary

Jacob Shapiro:

trends and which in the long run might make China look more responsible than

Jacob Shapiro:

other countries like China's the.

Jacob Shapiro:

Uh, bond yields, 30 year government bond yields are going down, whereas Japan's

Jacob Shapiro:

are surging to like record highs or not record highs, like 30, 40 year highs.

Jacob Shapiro:

Um, I don't know, like, how, how are you in, like, I'm not surprised

Jacob Shapiro:

that the Trump administration has discarded fiscal, uh, conservatism.

Jacob Shapiro:

Like I, one of the points I made for the last 12 months has been, I don't buy it.

Jacob Shapiro:

Like they're gonna blow out the deficit and they'll blow it

Jacob Shapiro:

out, probably even bigger than they did the first time around.

Jacob Shapiro:

Um, but man, the, the scale at which people are talking about this bill

Jacob Shapiro:

blowing out the deficit, I mean the, the scale of it even surprises me

Jacob Shapiro:

and I was expecting this, so I, I don't know how you feel about that.

Rob Larity:

Um, yeah, I think really one of the main misunderstandings, sort of

Rob Larity:

in the financial community or, or people who are following this stuff is this

Rob Larity:

notion of having the pedal to the metal.

Rob Larity:

Um, I think, you know, that is sort of reflective of a macro

Rob Larity:

environment of 10 years ago.

Rob Larity:

And, and we've talked about this in the last few conversations, but if you go

Rob Larity:

to the Trump first term, he was coming into office against a backdrop where

Rob Larity:

we needed some sexiness, we needed some irresponsibility, we needed,

Rob Larity:

um, a shot in the arm, so to speak.

Rob Larity:

And that's because we were kind of operating against a deflationary backdrop.

Rob Larity:

We needed, um, some kind of stimulus to, to drive that

Rob Larity:

pedal to the metal a little bit.

Rob Larity:

And it, it had some effect.

Rob Larity:

Um, like that, you know, it was a, it was a mixed data bag, you, you could say,

Rob Larity:

but it wasn't disastrous by any means.

Rob Larity:

What, um, you know, the first 2017 tax cuts and that did, you know,

Rob Larity:

and, and again, it reminds me of the late sixties, early seventies

Rob Larity:

and the Nixon administration coming in and sort of recognizing, oh,

Rob Larity:

you know, there are problems.

Rob Larity:

And then at the first sign of trouble turning back to sort of the fiscal

Rob Larity:

spigot and thinking, okay, well.

Rob Larity:

It's too early to deal with the issues.

Rob Larity:

So we're gonna go back to what has worked in the past.

Rob Larity:

And the problem is things work in the past until they create the circumstances

Rob Larity:

in which they no longer work.

Rob Larity:

And that's the situation where we are now, which is, if you look

Rob Larity:

at this bill, um, primarily we're talking about tax cuts, um, as the

Rob Larity:

source of these gaping deficits.

Rob Larity:

And that's a supply side stimulus.

Rob Larity:

So if you want, you know, always there's this fiction that tax cuts will pay for

Rob Larity:

themselves, which is never true, but sometimes they do stimulate the economy.

Rob Larity:

And the problem in this case is you can't use supply side stimulus, um,

Rob Larity:

in a situation where uncertainty and worry and um, sort of forward

Rob Larity:

projections are the problem.

Rob Larity:

Like you need demand side stimulus typically to give

Rob Larity:

people the confidence to invest.

Rob Larity:

And there's no new major demand side programs here.

Rob Larity:

They've walked back some of the more, um, you know, drastic cuts that they

Rob Larity:

had proposed to some things like the solar tax credit, utility scale,

Rob Larity:

solar, you know, things like that, that have been very popular in, in a lot

Rob Larity:

of states and, and real job drivers.

Rob Larity:

Um, but there's nothing particularly new.

Rob Larity:

We're mostly talking about, uh, supply side stimulus here.

Rob Larity:

And I just think there's, there's almost no circumstance in which

Rob Larity:

that has a huge positive impact and certainly not enough to offset what

Rob Larity:

we're seeing in markets today, which is 30 year US treasury yield approaching

Rob Larity:

a new high mortgage rates over 7%.

Rob Larity:

Um, those are huge factors that in all likelihood are gonna outweigh.

Rob Larity:

And then some, any of the potential kind of pedal to the metal effects.

Rob Larity:

Mm-hmm.

Rob Larity:

Like you, you're pedal to the metal, but you're driving into a brick wall.

Jacob Shapiro:

How far away is the brick wall?

Jacob Shapiro:

Is it two years away?

Jacob Shapiro:

Is it five years away?

Jacob Shapiro:

Is it 10 years away?

Jacob Shapiro:

Like, if, if you're trying to think about how to like position yourself

Jacob Shapiro:

accordingly, or if, if you're thinking about sort of the very, I'm

Jacob Shapiro:

thinking about the short term here.

Jacob Shapiro:

Like, okay, like yield's above 5%, that's a big psychological number and something

Jacob Shapiro:

that the media can really hang a hat on because, oh, now they're above 5%.

Jacob Shapiro:

But you know, if you look at historical relative terms,

Jacob Shapiro:

five percent's not that much.

Jacob Shapiro:

7% mortgage not that much, especially when you're going back

Jacob Shapiro:

like 30, 40 year time horizon.

Jacob Shapiro:

And I, I agree with you and I, and we'll get into this a little bit later.

Jacob Shapiro:

I wanna talk about, I. Private equity and biotech and, and some other things

Jacob Shapiro:

that are on the tops of our minds.

Jacob Shapiro:

But I, I feel like you could get a scenario where maybe pedal to the metal

Jacob Shapiro:

is the wrong thing, but you're, you're sort of juicing the economy like with like

Jacob Shapiro:

a, with a steroid shot, like the economy is sick, but give it a steroid shot and

Jacob Shapiro:

for the next two years, it could be, it be, it could be growing like gangbusters

Jacob Shapiro:

and this notion that you're gonna outgrow all the problems might seem clear until

Jacob Shapiro:

all of a sudden everything like to, to reference, um, uh, that reference we

Jacob Shapiro:

had a couple weeks ago, like, the music will stop and the music will stop very

Jacob Shapiro:

quickly and some big player will realize at first, and then everybody will pile in.

Jacob Shapiro:

So I'm, I'm just trying to get a sense from your brain.

Jacob Shapiro:

I know I'm asking you an impossible question, like, how long can we do this?

Jacob Shapiro:

Can we do this for five years?

Jacob Shapiro:

Can we do this for 15 years?

Jacob Shapiro:

Because you don't wanna miss like.

Jacob Shapiro:

The, the, the juice era.

Jacob Shapiro:

Like if, if you're going long home runs, like you don't wanna, you

Jacob Shapiro:

don't wanna like get out of the home run market right before Sammy Sosa

Jacob Shapiro:

and Mark McGuire are squaring off.

Jacob Shapiro:

Right.

Jacob Shapiro:

And right after You wanna do it after when they have the new rules.

Rob Larity:

Yeah.

Rob Larity:

The juice era is already over.

Rob Larity:

And I can say that with some confidence because gold prices are hitting new highs.

Rob Larity:

Bitcoin is hitting new highs.

Rob Larity:

Yields are like, Mr. Market is telling us, hey, the juice is already killing us.

Rob Larity:

Um, and that's really important because it would be one thing if this was,

Rob Larity:

oh, just kick the can down the road.

Rob Larity:

Like there's no more road according to these markets.

Rob Larity:

And that's why intermarket analysis is so important.

Rob Larity:

Like you have to be very precise.

Rob Larity:

Like, what is the question here?

Rob Larity:

Is it, at what point does the US reach sort of an unsustainable escape

Rob Larity:

velocity on the debt accumulation?

Rob Larity:

Mm-hmm.

Rob Larity:

Like, that's a complicated question.

Rob Larity:

'cause at some point they could just.

Rob Larity:

Paying interest rates or intervene like this, it's not a linear sort of thing.

Rob Larity:

So there's the macro question, which arguably like on the current

Rob Larity:

trajectory, you know, interest rates or I'm sorry, interest payments

Rob Larity:

are already approaching or have exceeded a trillion dollars a year.

Rob Larity:

Yeah.

Rob Larity:

So we're in, like, we are in the danger zone.

Rob Larity:

Um, and that's having a real income statement effect.

Rob Larity:

Like, like this is one of the, one of the problems here in, in the

Rob Larity:

analogy of sort of the juice, is there's balance sheet effects and

Rob Larity:

there's income statement effects.

Rob Larity:

So yes, historically speaking rates where they are today are not particularly

Rob Larity:

high relative to, you know, heights they've reached like in the mid nineties,

Rob Larity:

1994, like, you know, it's sort of more normal on that very long-term horizon.

Rob Larity:

But the difference that is that the balance sheet is completely different,

Rob Larity:

the balance sheet is super leveraged.

Rob Larity:

When you're looking at the public sector, and you know, in many cases the, the

Rob Larity:

corporate sector too, not households.

Rob Larity:

Households are okay.

Rob Larity:

Corporate sector and especially government are not.

Rob Larity:

Okay.

Rob Larity:

And this is where you have the, the juice analogy, like immediately hits the, the

Rob Larity:

wall because, you know, that has an income statement effect that's very rapid because

Rob Larity:

you're refinancing into those rates.

Rob Larity:

You're, you're servicing that debt on that bloated liability

Rob Larity:

side of your balance sheet.

Rob Larity:

And, and that has effects in just like how the money's flowing around.

Rob Larity:

So I think there's, there's already a macro issue there.

Rob Larity:

And, um, you know, the markets are telling us what, how the markets are

Rob Larity:

interpreting it, at least the bond markets and the currency markets, which are,

Rob Larity:

you know, dwarf the, the equity markets.

Rob Larity:

Um.

Rob Larity:

And, and the other thing is like, what are companies saying?

Rob Larity:

So are companies looking at this bill and saying, oh yeah, like let's go, let's go

Rob Larity:

ramp up CapEx, let's go, you know, raise our, like, no, no, it's the opposite.

Rob Larity:

You know, we just had Q1 earning season, which ended, you know,

Rob Larity:

10 days ago, two weeks ago, depending, and that was a disaster.

Rob Larity:

Um, lots and lots of companies withdrawing their guidance, pulling in the horns,

Rob Larity:

talking about sort of macro uncertainty.

Rob Larity:

Um, you know, uh, that is, that is not a sign that normalcy is here or

Rob Larity:

that that level of confidence that you need for investment to, to drive

Rob Larity:

again is, is necessarily coming.

Jacob Shapiro:

Mm-hmm.

Jacob Shapiro:

Anything else you wanna say about, uh, like US markets before

Jacob Shapiro:

we turn to a different topic?

Jacob Shapiro:

No,

Rob Larity:

I don't think so.

Rob Larity:

Okay.

Jacob Shapiro:

Um.

Jacob Shapiro:

Not that they're, you know, a nice rosy, uh, optimistic point

Jacob Shapiro:

of view from us on that score.

Jacob Shapiro:

Cool.

Jacob Shapiro:

Um, l let's turn to, um, um, l let, let's turn to biotech and

Jacob Shapiro:

in particular Chinese biotech.

Jacob Shapiro:

This is gonna be one of those conversations listeners where Rob and

Jacob Shapiro:

I are at the very beginning stages of talking about something and he and I

Jacob Shapiro:

have not had a chance to actually talk about this, and our schedules are crazy.

Jacob Shapiro:

So, Rob, I just wanna talk to you as if like, I wasn't actually talking to you

Jacob Shapiro:

on a podcast and we'll put it out anyway.

Jacob Shapiro:

'cause I know this is something you've been thinking about and it's

Jacob Shapiro:

something I've been thinking about.

Jacob Shapiro:

And I think it actually does connect with exactly what you

Jacob Shapiro:

just said, which is, you know, are American companies investing more?

Jacob Shapiro:

Are the circumstances that led to American growth and American outperformance,

Jacob Shapiro:

whether it's in semiconductors or biotech, in some of these, in some of

Jacob Shapiro:

these areas, are those fundamentals gone and have they actually shifted to

Jacob Shapiro:

other places in the world, namely China?

Jacob Shapiro:

Um.

Jacob Shapiro:

When you start sort of looking, you know, last 40, 50 years, the United States

Jacob Shapiro:

has really been the king of biotech.

Jacob Shapiro:

I don't think that that's a, a crazy sort of assertion to make.

Jacob Shapiro:

Um, but if you start looking sort of closer the last 10 to 15

Jacob Shapiro:

years, like China's flashing all the right signals, and some of

Jacob Shapiro:

that is for popular consumption.

Jacob Shapiro:

Like so many people like to, you know, flaunt this idea that, uh, you

Jacob Shapiro:

know, China has more, has doubled its clinical trial activity and it's

Jacob Shapiro:

doubled the number of articles that it's published in various journals.

Jacob Shapiro:

Like I know I, I, I'm not trying to throw shade at journals, but like I for

Jacob Shapiro:

instance, knew people at a Russian think tank who decided they wanted to get more

Jacob Shapiro:

articles into foreign affairs journals to make their university look better.

Jacob Shapiro:

So they were just doing things to try and get as many articles as they could

Jacob Shapiro:

possibly get published in these journals.

Jacob Shapiro:

So like there, there is some level, um, of sort of, um, emptiness to those

Jacob Shapiro:

things, but at the same time, like, um, there's sort of a couple different.

Jacob Shapiro:

Things that supported the US biotech industry, or at least

Jacob Shapiro:

the way that I understand it.

Jacob Shapiro:

Um, there was funding for research and for universities in particular

Jacob Shapiro:

and that public-private partnership and the US government really

Jacob Shapiro:

putting its foot forward there.

Jacob Shapiro:

I mean, you had, you had US presidents, I believe it was Lyndon Johnson, I think

Jacob Shapiro:

it was Lyndon Johnson, I forget which president said we're gonna cure cancer.

Jacob Shapiro:

I mean, you, you had that sort of.

Jacob Shapiro:

Shoot for the moon type of thinking in the United States and you had dollars

Jacob Shapiro:

that went to those sorts of things.

Jacob Shapiro:

Um, you've had a low interest rate environment and lots of

Jacob Shapiro:

venture capital and startup funding really since post 2008.

Jacob Shapiro:

And biotech is the perfect place for that.

Jacob Shapiro:

'cause you gotta do a lot of expensive research and hire a lot, hire a lot

Jacob Shapiro:

of expensive people, and you don't know if the technology's gonna work.

Jacob Shapiro:

Um, so in a low or zero interest rate environment or in an environment where

Jacob Shapiro:

a pandemic coming and you're doing operation warp speed, yeah, there's

Jacob Shapiro:

probably a lot of money out there for r and d for us biotech companies.

Jacob Shapiro:

But that's starting to go away.

Jacob Shapiro:

And we can talk, you can go down that rabbit hole too.

Jacob Shapiro:

I mean, this is something we talk about a lot at Bespoke.

Jacob Shapiro:

There was an FT article this week about, you know, US universities like Harvard

Jacob Shapiro:

and Yale exploring discounted secondary market sales of private equity stakes.

Jacob Shapiro:

I'd love to know how many of those are like shiny biotech startups that

Jacob Shapiro:

didn't actually pan out, I don't think we'll ever actually know.

Jacob Shapiro:

Um, so there's that.

Jacob Shapiro:

And then.

Jacob Shapiro:

Attracting top tier talent from abroad.

Jacob Shapiro:

This really like started around COVID and the things that the Trump administration

Jacob Shapiro:

has done in the first five months of this year have exacerbated it.

Jacob Shapiro:

Um, the United States, like US universities are still at the top.

Jacob Shapiro:

But there's fewer and fewer positions.

Jacob Shapiro:

Um, there's less and less optimism that the United States is a place where you

Jacob Shapiro:

can make a career in this sense, not just for very, very smart foreigners,

Jacob Shapiro:

but for us scientists themselves.

Jacob Shapiro:

Like anecdotally, I have friends who were in this space who suddenly the money is

Jacob Shapiro:

drying up and they're looking towards, well, could I tolerate living in China?

Jacob Shapiro:

Could I move to Europe?

Jacob Shapiro:

Like what are some of the, uh, changes I'm willing to make in my life in order

Jacob Shapiro:

to participate in top tier research?

Jacob Shapiro:

Because it doesn't look like it's gonna be happening in the

Jacob Shapiro:

United States going forward.

Jacob Shapiro:

And here, like China is singing a very different tune.

Jacob Shapiro:

'cause yes, they're talking about austerity at a top level, but the

Jacob Shapiro:

government has said very clearly, no, biotech is one of the commanding heights

Jacob Shapiro:

of the sort of tech economy going forward.

Jacob Shapiro:

They have multiple five-year plans and spending plans and, you know, different

Jacob Shapiro:

hubs that they want to create within China that are gonna be hubs that expand this.

Jacob Shapiro:

Um, people talk about China's demographics as being a negative, but

Jacob Shapiro:

when you have a bunch of old people and not a great healthcare system and

Jacob Shapiro:

you need social stability, probably a good idea to throw as much money as

Jacob Shapiro:

possible as you could at this industry.

Jacob Shapiro:

And you're gonna have way more data and way more old, old people to

Jacob Shapiro:

treat, uh, than you necessarily will in some other parts of the world.

Jacob Shapiro:

Um, and in, and China has also become just like it has in every single

Jacob Shapiro:

manufacturing supply chain in the world.

Jacob Shapiro:

Like they produce a lot of the precursors, like they have gotten

Jacob Shapiro:

involved in biotech in an incredible way.

Jacob Shapiro:

Just in terms of like the things that are, you know, like the ibuprofen that

Jacob Shapiro:

I'm gonna g that I give my daughter when she has an ear infection, that's

Jacob Shapiro:

probably some of the ingredients are sourced from China or India.

Jacob Shapiro:

Um, and you start going down the list of medications and things

Jacob Shapiro:

like that, that's all there.

Jacob Shapiro:

And there's been this huge growth in, in Chinese biotech in general.

Jacob Shapiro:

So I'm rambling a little bit, but I'm trying to, to connect what we were,

Jacob Shapiro:

what we were talking about before.

Jacob Shapiro:

And here's China, which everybody says demographics sucked, uh, sucks.

Jacob Shapiro:

Structural problems.

Jacob Shapiro:

Real estate bubble that's never gonna be fixed.

Jacob Shapiro:

Everything else.

Jacob Shapiro:

And yet, like burgeoning biotech industry, it doesn't take long to go

Jacob Shapiro:

find McKinsey 50 page decks about what the opportunity set is, or US government

Jacob Shapiro:

reports about how China is stealing the, uh, the cutting edge here and that the

Jacob Shapiro:

United States government needs to get back on track immediately, which the

Jacob Shapiro:

United States government is not doing.

Jacob Shapiro:

So.

Jacob Shapiro:

Um, I, I rambled a little bit, but that, that's the setup.

Jacob Shapiro:

Let's talk about it.

Rob Larity:

No, no, not a ramble.

Rob Larity:

I mean, there's so many different interlocking issues.

Rob Larity:

I think you covered a lot of them really well.

Rob Larity:

Um, where to begin, I think just to, to start with first principles,

Rob Larity:

like, let's not get outta, you know, get out of proportion here.

Rob Larity:

Um, the US is a biotech juggernaut and that's not gonna change overnight.

Rob Larity:

Um, like yes, obviously the NIH is a major factor in that.

Rob Larity:

There's tons of stuff going on with the FDA, with the NIH itself, but the

Rob Larity:

sheer amount of wealth that is in the US that is financing, um, innovation

Rob Larity:

and research is just beyond compare.

Rob Larity:

Even China can't touch it can't even come close right now.

Rob Larity:

Um, so the US has enormous strengths.

Rob Larity:

Like if you look at something like the Ark Institute, which is financed by.

Rob Larity:

Um, Patrick Collison, tech entrepreneur, like that sort of thing is where the

Rob Larity:

US is going to continue to shine.

Rob Larity:

And when you look at sort of where still the most interesting cutting

Rob Larity:

edge stuff is happening, predominantly it's still in the US so let's not,

Rob Larity:

you know, just make sure we're not being doom and gloom about the US.

Rob Larity:

'cause relatively things are still good, but it's similar to the

Rob Larity:

Multipolarity thesis where the US is going to be a very powerful force

Rob Larity:

in this area as well, but they're not gonna be the only force anymore.

Rob Larity:

And, um, you know, you mentioned sort of China's property bubble, the treadmill

Rob Larity:

to hill all of these things and yet at the same time, look at what they're doing

Rob Larity:

in batteries and EVs and grid technology and biotech and, and all of this stuff.

Rob Larity:

But those are two parts of the same coin, or two sides of

Rob Larity:

the same coin, I should say.

Rob Larity:

Um.

Rob Larity:

Sort of this kind of, uh, the Chinese model, which is really based on to

Rob Larity:

some extent guiding and commandeering state priorities around capital

Rob Larity:

allocation results in stuff like, you know, cattle and BYD and you know,

Rob Larity:

the, the supply chains getting built to support companies like that and

Rob Larity:

biotech and, and all this sort of stuff.

Rob Larity:

But it also means you have treadmill to hill, you know, ghost, uh, cities in

Rob Larity:

the middle of nowhere and, and capital misallocation just on huge scale.

Rob Larity:

So it's always a race, like how much value can they create with the good

Rob Larity:

stuff versus how much do they throw down a hole with the bad stuff.

Rob Larity:

Um, and it's just the nature of the system.

Rob Larity:

So that's kind of working as intended.

Rob Larity:

And I think just like China has caught up and, and in many ways

Rob Larity:

surpassed, depending on which specific area you're talking about.

Rob Larity:

Surpass the US in, in a lot of these areas, like biotech, they're a player.

Rob Larity:

Like that's, that's clear.

Rob Larity:

And that is the most interesting thing because it wasn't very long

Rob Larity:

ago that they were just nothing like Chinese biotech was a joke.

Rob Larity:

Nothing was happening.

Rob Larity:

Like I think it was only like two years ago.

Rob Larity:

Um, you know, uh, which was the leading C-C-C-D-M-O provider

Rob Larity:

to us and European biotechs.

Rob Larity:

They got cut out, uh, from the bios secure act from providing this to, to

Rob Larity:

us customers providing their services.

Rob Larity:

And it was viewed as like, oh my God, these guys are gonna

Rob Larity:

be just completely destroyed.

Rob Larity:

Mm-hmm.

Rob Larity:

Since then, you know, it's sort of, I mean, it's too early to say 'cause uh,

Rob Larity:

they're not as far along in the recovery period as Huawei, but it has been sort

Rob Larity:

of a Huawei kind of scenario where I. They're, they're probably gonna be fine.

Rob Larity:

And, and guess what?

Rob Larity:

Now they really dominate the burgeoning Chinese scene.

Rob Larity:

So this has happened very fast, and we do have to keep it in proportion, but we also

Rob Larity:

have to recognize that this is for real.

Rob Larity:

It's not just marketing and, and it's not, um, it's not a flash in the pan.

Rob Larity:

Like very clearly they've put in place some of the fundamentals

Rob Larity:

to do this at scale, as you say.

Rob Larity:

Like if you have, if you're gonna have this industry because it's so tied to

Rob Larity:

sort of local regulatory, uh, apparatus, you need to have scale to sell into.

Rob Larity:

Like you can't, it's very difficult to export these kind of innovations

Rob Larity:

unless you have some sort of deal.

Rob Larity:

So like Australia does a lot of early stage biotech research because they

Rob Larity:

have a favorable sort of, um, pathway to get FDA approval and stuff like that.

Rob Larity:

But that's more the exception than the rules.

Rob Larity:

So usually you need a big market.

Rob Larity:

Um, to do this, Europe, China, United States for the most part, and China,

Rob Larity:

you know, they've planted their marker.

Rob Larity:

So, you know, I think they're here to say, how do you, how do you

Rob Larity:

get positive exposure to that?

Rob Larity:

Like, we have a lot of different things around this, you know, that we're doing,

Rob Larity:

but that's more of a bottom up question.

Rob Larity:

But certainly as a theme, I, I think it's, I think it's pretty legit.

Jacob Shapiro:

Yeah.

Jacob Shapiro:

I want to give you some stats because I, I think you're right in terms

Jacob Shapiro:

of a snapshot of today, the United States is still the juggernaut.

Jacob Shapiro:

This is sort of the, in the same vein as, as the conversation

Jacob Shapiro:

with Multipolarity, but.

Jacob Shapiro:

When I look at the data, and this is like, you know, I've started

Jacob Shapiro:

my deep dive into this this week.

Jacob Shapiro:

So maybe three weeks from now I'll be here saying, eh, like, uh, this data, I,

Jacob Shapiro:

I found some other data that's better.

Jacob Shapiro:

But, but here's just a couple of data points that like, really I sort of sat

Jacob Shapiro:

up in my chair when I read some of these.

Jacob Shapiro:

Um, if you look at share of clinical trials based on a company's headquarters

Jacob Shapiro:

in 2013, China accounted for less than 5% globally as of 2023, almost 30%.

Jacob Shapiro:

And the United States has declined from sort of between 37, 38 down to 34.

Jacob Shapiro:

If you look at global, um, shares of biotechnology, venture

Jacob Shapiro:

capital raised the United States.

Jacob Shapiro:

That's declined from about 70% of global share to 60% from China.

Jacob Shapiro:

It went to basically five to almost 20%.

Jacob Shapiro:

Um, when you look at, um, STEM PhD graduates in 2000, US universities

Jacob Shapiro:

awarded more than twice as many STEM doctoral degrees as Chinese universities.

Jacob Shapiro:

Uh, in 2019, uh, China awarded almost 50,000 STEM PhD degrees.

Jacob Shapiro:

United States 33,000.

Jacob Shapiro:

So getting lapped there in general.

Jacob Shapiro:

Um, up to this, uh, these next stats are from CSIS up to 90% of the most widely

Jacob Shapiro:

used medications in the United States, including ibuprofen and acetaminophen.

Jacob Shapiro:

So your Tylenol are imported from China as Chinese investments have surged in

Jacob Shapiro:

the biotech space in the last 10, 20 years, federal funding for biotech is

Jacob Shapiro:

actually flat in the US since the 1960s.

Jacob Shapiro:

And the regulatory environment has gotten even more sort of complicated.

Jacob Shapiro:

There was a bio survey, um, that surveyed 124 different biopharma companies

Jacob Shapiro:

inside of the United States, and they found that 79% of them, so 79% of 124

Jacob Shapiro:

US biopharma companies had contracts with China contract manufacturing

Jacob Shapiro:

organizations or contract development and manufacturing organizations.

Jacob Shapiro:

And that's so important because it's not like you can just

Jacob Shapiro:

switch that to the United States.

Jacob Shapiro:

I recall the conversation we had with, uh, Tomas.

Jacob Shapiro:

Uh.

Jacob Shapiro:

Uh, on the podcast that, uh, well, I guess that was the beginning of

Jacob Shapiro:

the year, so many episodes ago.

Jacob Shapiro:

But one of the questions, uh, we asked Tomas was, Hey, if, if we could wave a

Jacob Shapiro:

magic wand and there were no regulatory problems and there was operation warp

Jacob Shapiro:

speed from the US government, how fast would it take you to spin up US refining

Jacob Shapiro:

capacity for some of the rare earths and other minerals that you're looking at?

Jacob Shapiro:

And he said, without hesitation, eh, like seven years is probably a good estimate.

Jacob Shapiro:

Maybe that's a little conservative, but seven years, a good estimate.

Jacob Shapiro:

Um, bio found that it would take a lot of these biopharma

Jacob Shapiro:

companies that they surveyed up to eight years to change partners.

Jacob Shapiro:

So even if you want to pass something like the Bio Secure Act, or if you want, if

Jacob Shapiro:

the Trump administration considers other things to try and move, um, dependents

Jacob Shapiro:

away from some of these, you know, Chinese contract manufacturing organizations,

Jacob Shapiro:

uh, okay, you're gonna need seven to eight years to build either the domestic

Jacob Shapiro:

capacity or the nearshoring capacity to do some of these sorts of things.

Jacob Shapiro:

So I totally grant that the like.

Jacob Shapiro:

Snapshot today, the United States is still the juggernaut,

Jacob Shapiro:

but Arrow is pointing down.

Jacob Shapiro:

And for China, the arrow is pointing up.

Jacob Shapiro:

And even though they don't have the same level of experience of turning

Jacob Shapiro:

cool science into products, and even though they don't have a history of

Jacob Shapiro:

venture capital and all these different things like creating products that make

Jacob Shapiro:

profitable companies in general, as with so many of the things that we talking

Jacob Shapiro:

about, they are the one making things.

Jacob Shapiro:

They are the ones that make the things that go into the

Jacob Shapiro:

things that make the products.

Jacob Shapiro:

And if you get into a real decoupling sort of scenario, like, okay, like they can't

Jacob Shapiro:

do the high-end stuff, but we can't do any of the high-end stuff without them either.

Jacob Shapiro:

And they are pushing really, really hard on the science and trying to get smart.

Jacob Shapiro:

So maybe it'll take a long time, but I don't know, like the, the

Jacob Shapiro:

arrow seems to be pointing up to me.

Jacob Shapiro:

Um, am I, is is that too doom and gloom?

Jacob Shapiro:

Because you said not to go doom and gloom and I'm looking at the

Jacob Shapiro:

data and I'm like, I don't know.

Jacob Shapiro:

First look looks pretty gloomy to me.

Rob Larity:

China has a lot of advantages.

Rob Larity:

Um.

Rob Larity:

One of the best books to read on this subject of venture capital and biotech

Rob Larity:

is Bill Jane Way's, um, doing capitalism in the, in the financial economy, or

Rob Larity:

I forget what it's called, something like that Bill Jane Way's book.

Rob Larity:

And in it he points out, you know, he was traditionally a software VC and he pointed

Rob Larity:

out the difficulty of VC in biotech is you know exactly what your market is like.

Rob Larity:

You can literally say, okay, there's 482,000 people with

Rob Larity:

this disease every year.

Rob Larity:

That's we can sell to immediately if we can get this right,

Rob Larity:

which is very different.

Rob Larity:

But at the same time, getting the science to work, getting a product that

Rob Larity:

actually can get through, you know, the gauntlet of, of clinical trials and

Rob Larity:

all of that is so long and so expensive that even though you kind of de-risk

Rob Larity:

the market size like the TAM issue.

Rob Larity:

Um, like with very few exceptions, there's, there's very few like really

Rob Larity:

successful recurring biotech VCs.

Rob Larity:

Like who's the Andreessen Horowitz of biotech?

Rob Larity:

Like, you know, I'm sure there's some firms that have had success, but it's

Rob Larity:

very difficult to do and I bring that up because when you think about discount

Rob Larity:

rates, when you think about time horizon, and this is one of the issues when we talk

Rob Larity:

about uncertainty and why what Trump is doing, getting this back to the macro is

Rob Larity:

not gonna fix a lot of these problems.

Rob Larity:

The problem in many ways is discount rate and uncertainty.

Rob Larity:

You're not gonna go build a factory if you don't know what the hell the

Rob Larity:

policy is gonna be five years from now.

Rob Larity:

You're not gonna invest in a biotech firm.

Rob Larity:

And we see this on the ground up 'cause we get a lot of visibility into early

Rob Larity:

stage biotech and med tech companies.

Rob Larity:

And they're suffering because people are looking at what's happening at the

Rob Larity:

FDA and they're saying, what the hell is the, is the length of the pipeline here?

Rob Larity:

Is this gonna take four years or is it gonna take seven years?

Rob Larity:

Is it gonna cost $30 million to get to phase two, or is it gonna cost

Rob Larity:

$70 million to get to phase two?

Rob Larity:

And there's so much uncertainty around that.

Rob Larity:

At the same time that the 30 year treasury yields is making new highs, it just

Rob Larity:

strangles private capital allocation.

Rob Larity:

I mean this is going back to Cain's, like this is classic, you know, stuff here.

Rob Larity:

And I say that because, you know, China does have, the Chinese capital allocation

Rob Larity:

model does have a, a real advantage there because it's not market driven.

Rob Larity:

In many cases it can be driven by political dick to, it can

Rob Larity:

be driven by other factors.

Rob Larity:

And this is getting to one of the, like, I don't want to be all doom and gloom.

Rob Larity:

I, I think that's a reason to be very bullish on China and what they can do.

Rob Larity:

And let's be clear like this is not a competition.

Rob Larity:

The more good stuff that comes out of this industry, the

Rob Larity:

more humanity just does well.

Rob Larity:

So it's not, you know, bombs or semiconductors or missiles or something.

Rob Larity:

Like, let's just keep that in perspective.

Rob Larity:

So we want everyone to win here.

Rob Larity:

Um, it's not gonna make the US suffer If, you know Chinese, uh, elderly

Rob Larity:

people get cured of Alzheimer's, like that's just a win-win for everybody.

Rob Larity:

But, you know, I think there's reasons to be very bullish on,

Rob Larity:

on the Chinese opportunity.

Rob Larity:

I wouldn't say doom and gloom for the US 'cause I, I, I do wanna speak to

Rob Larity:

that, but one of the sort of hidden advantages of the US is I think, sort

Rob Larity:

of the growing influence of impact capital and sort of social investing.

Rob Larity:

And, and this is something I've really come to appreciate more since we've been

Rob Larity:

doing the, you know, work with bespoke and, and seeing how people are doing this

Rob Larity:

at large scale is, that's sort of another way of, of the Chinese model in some ways.

Rob Larity:

Like it's not financially driven only it can have.

Rob Larity:

You know, quote unquote political motives and, you know, social motives, o other

Rob Larity:

reasons to invest in these ventures.

Rob Larity:

Like I just was speaking with someone, um, this morning I had coffee, uh, with

Rob Larity:

a guy who's involved in a, in a biotech startup, and they're doing a gene editing

Rob Larity:

thing for congenital heart failure.

Rob Larity:

And, um, they're in the process of raising, you know, 30 or $40 million

Rob Larity:

from a daf, a donor-advised fund and, and doing it through a grant process.

Rob Larity:

Um, that's a huge, when I, we talk about the pools of wealth and what people

Rob Larity:

invest in and why that's a huge sort of un under-recognized and strength

Rob Larity:

of the US that is probably gonna get bigger, uh, in the next few years.

Rob Larity:

That said, it's not that big relative to the existing mechanisms

Rob Larity:

and all those other problems about uncertainty and VC throttling

Rob Larity:

back that is gonna outweigh that.

Rob Larity:

It's just a way of saying like, the US isn't totally screwed in any way.

Rob Larity:

It's just relative, you know, getting to the Multipolarity thesis,

Rob Larity:

China is going to continue rising.

Rob Larity:

They have these unique advantages and the US does have major problems

Rob Larity:

even though, you know, a lot of those strengths still are there.

Rob Larity:

Um,

Jacob Shapiro:

yeah, I'm, I'm struck when you say that about, and I don't know if

Jacob Shapiro:

I'm just making everything comport to my thesis here 'cause I'm in danger of

Jacob Shapiro:

doing that, but when you think about.

Jacob Shapiro:

Even the notion of tariffs and of protectionist US policy and

Jacob Shapiro:

of the overtones and current US policy to the early 19 hundreds.

Jacob Shapiro:

I mean, even in what you just said, in the early 19 hundreds, there was a real

Jacob Shapiro:

movement in the United States towards social welfare that was privately funded.

Jacob Shapiro:

The government was not the one that was actually funding

Jacob Shapiro:

all these sorts of things.

Jacob Shapiro:

It really isn't until World War I that the size of the US

Jacob Shapiro:

government increases markedly.

Jacob Shapiro:

And so you had, um, you know, this real movement in the United States,

Jacob Shapiro:

whether it was making factories safer or in educating children or like, or in

Jacob Shapiro:

basic hygiene, things like that, where you had, and you know, there was also

Jacob Shapiro:

the, the temperance side of this too, making people drink less, which, uh,

Jacob Shapiro:

maybe went, went a little bit too far.

Jacob Shapiro:

Um, or not, but may, maybe we have some temperance radicals

Jacob Shapiro:

listening to the podcast.

Jacob Shapiro:

I don't wanna, I don't wanna assume anything.

Jacob Shapiro:

Um.

Jacob Shapiro:

But you know, you're talking like that, that sort of notion is very antiquated.

Jacob Shapiro:

Like we live in a world where like, like you said, it's too

Jacob Shapiro:

small to make a huge difference.

Jacob Shapiro:

And many of the amazing changes that have happened inside of the

Jacob Shapiro:

United States happened because the United States government, for

Jacob Shapiro:

better or for worse, we can agree or disagree from a policy perspective on

Jacob Shapiro:

whether it's the right thing or not.

Jacob Shapiro:

But since World War I, the US government has basically just gotten

Jacob Shapiro:

bigger and bigger and bigger and has taken on more and more and more.

Jacob Shapiro:

And that has come with certain problems, but it's also come on, unleashing

Jacob Shapiro:

capital and focus on a national scale.

Jacob Shapiro:

Not according to dicta, like you said, as as in a dictatorship.

Jacob Shapiro:

But you know, in certain moments, yes.

Jacob Shapiro:

Like semiconductors is a story there too.

Jacob Shapiro:

And I hate being the cynical one in our conversation, but you say that

Jacob Shapiro:

this is gonna be better for the world.

Jacob Shapiro:

Uh.

Jacob Shapiro:

Yeah, maybe overall, but not necessarily for the United States.

Jacob Shapiro:

If China cures Alzheimer's and China and the United States are in a great

Jacob Shapiro:

grand geopolitical battle, um, and, uh, we can't, and the United States

Jacob Shapiro:

cannot replicate what China does.

Jacob Shapiro:

I mean, China's gonna use that against the United States like we already saw,

Jacob Shapiro:

like in COVID vaccine diplomacy and the hoarding of PPE and how really

Jacob Shapiro:

geopolitically nasty things got about a relatively minor, uh, pandemic.

Jacob Shapiro:

In the grand scheme of things, when you look at other pandemics and the mortality

Jacob Shapiro:

rate and things like that, like cynically, like I, I think we're imagining a world

Jacob Shapiro:

in which if the United States is not at the center here and there are other

Jacob Shapiro:

centers that are doing so much better, um, yeah, I mean, I, I guess maybe you'll

Jacob Shapiro:

tell me that the technology will diffuse and it'll, it'll go around everywhere.

Jacob Shapiro:

But the cynic in me sort of sees, well, no, like if China's at the

Jacob Shapiro:

center of these things, um, today, then like life relatively in

Jacob Shapiro:

the United States will be worse.

Jacob Shapiro:

It's, it's not a foregone conclusion that, that that technology will diffuse.

Rob Larity:

Well, from my perspective, if you said to me that the world is gonna get

Rob Larity:

a cure for Alzheimer's, but the Chinese are gonna be the only ones to develop

Rob Larity:

it, I would want to live in that world.

Rob Larity:

Um, but let me, let me give like a bear case on the US 'cause I can, I can argue

Rob Larity:

a bear case and this is how I see it.

Rob Larity:

I don't necessarily believe this, but this is how I would lay it out, which is

Rob Larity:

that you take sort of an exceptionalist view of the US biotech industry over

Rob Larity:

the last, you know, 40, 50 years and say, okay, this is like, you know,

Rob Larity:

the New York jazz scene in the 1950s.

Rob Larity:

Like the right places, the right people just happen to be together.

Rob Larity:

You know, this, this is Renaissance Florence.

Rob Larity:

Like something happens, some like, 'cause if you look at the rest of the

Rob Larity:

world, biotech is something that doesn't really happen almost on anywhere else.

Rob Larity:

Even Europe, which is extraordinarily rich and successful in so many levels like.

Rob Larity:

The level of biotech research that they're doing, really like at the edge of

Rob Larity:

what's happening is, is not remotely in proportion to their level of development.

Rob Larity:

So there's something kind of weird about biotech, and I suspect maybe there's

Rob Larity:

something about sort of these, like the equilibrium for private capital

Rob Larity:

to do this, it's just not there.

Rob Larity:

So you need some weird mixture of like the right people in the right place and

Rob Larity:

the right sort of financing structures.

Rob Larity:

And I guess my bear case would be like, you know, is that the case?

Rob Larity:

Is this renaissance Florence?

Rob Larity:

Because if Florence goes down, you can't just replicate that.

Rob Larity:

Like if the magic sauce is lost, like that could just be a, a net loss.

Rob Larity:

It's not just like, oh, these people will go do this somewhere else, or this

Rob Larity:

activity will happen in India, or you know, whatever, Turkey or something like,

Rob Larity:

maybe it just doesn't happen anymore.

Rob Larity:

And, and to support that, like, just an anecdote.

Rob Larity:

So, you know, I'm originally was in Cambridge for all so many years,

Rob Larity:

and most of my friends are somehow related to scientific research.

Rob Larity:

And Juliet is obviously, as you know, um, so I see a lot of people in, in that area.

Rob Larity:

And, um, the, the thing that strikes me is a how dependent, truly cutting

Rob Larity:

edge research is on immigrants.

Rob Larity:

Um, that is a huge factor.

Rob Larity:

Like if you look at the top labs at Harvard for instance, they are

Rob Larity:

60, 70% non-US born researchers.

Rob Larity:

Um, so the US has been this enormous magnet for talent and

Rob Larity:

that is really under threat.

Rob Larity:

Um, you know, some of my, my closest friends, just to give one anecdote,

Rob Larity:

so I'm really good friends with a Brazilian couple, young Brazilian couple.

Rob Larity:

They're both scientists.

Rob Larity:

They come from Sao Paulo.

Rob Larity:

They've been here for like seven or eight years, uh, on a green

Rob Larity:

card, which they got recently.

Rob Larity:

One is the head of a lab, one works at a private biotech company.

Rob Larity:

Both of them are, they just had to go back to Brazil.

Rob Larity:

They were terrified they wouldn't be allowed back into the country.

Rob Larity:

Um, they're both like reporting that everyone they know is just,

Rob Larity:

they don't know what to do.

Rob Larity:

Um, they're, they're feeling whether it's justified or not, there's an impression

Rob Larity:

that they're gonna be kicked outta the country, that they're gonna be hunted.

Rob Larity:

Like there's some issue that's gonna emerge because

Rob Larity:

there's so much stress around.

Rob Larity:

We, we take this for granted.

Rob Larity:

As you know, American citizens.

Rob Larity:

There's so much stress around the process of getting your green card, doing the

Rob Larity:

application, going through the process.

Rob Larity:

Trying to get it through.

Rob Larity:

Don't, don't screw something up, like the stressful levels are through the roof.

Rob Larity:

Uh, one of their friends from Brazil went back to Brazil last year to go work,

Rob Larity:

uh, in a lab in, in, in Port Alegre.

Rob Larity:

And that was weird.

Rob Larity:

Like he just, he just went back to Brazil and I don't know, like

Rob Larity:

maybe they'll stay long term.

Rob Larity:

They've, they've kind of put down roots, but at the margin it's gonna be more

Rob Larity:

difficult to attract that talent if that's the zeitgeist around what's going on.

Rob Larity:

And people see that we're gutting the public institutions that stand behind

Rob Larity:

a lot of the kind of basic research.

Rob Larity:

'cause you know, we have to remember too, it, it's sort of like government

Rob Larity:

and, and the bureaucracies, or I'm sorry, government and private industry

Rob Larity:

where people go back and forth.

Rob Larity:

Like people will come here to do research and then they'll hop to.

Rob Larity:

A biotech private sector job like that happens a lot because most people,

Rob Larity:

especially if they don't, if they're coming from abroad, they're not usually

Rob Larity:

coming from a private sector background.

Rob Larity:

'cause there are no biotechs abroad.

Rob Larity:

It's, you know, they're, they're, they've just been educated and

Rob Larity:

now they're looking for, you know, they're gonna continue in the ac in

Rob Larity:

the academic, you know, uh, role.

Rob Larity:

But that is really, like, that's a bottleneck that's dependent on grants and

Rob Larity:

labs and universities and, you know, all of this stuff that we're talking about.

Rob Larity:

So, you know, it's easy to underestimate how much, if that bottleneck gets

Rob Larity:

squeezed, that you're ultimately squeezing the flow of people also to the private

Rob Larity:

sector and to, you know, the big biotechs in Kendall Square and, and all of that.

Rob Larity:

Like, it's just very fragile.

Rob Larity:

I think that that would be my, my bear case is that it's much

Rob Larity:

more fragile than we think.

Rob Larity:

It's much more of a like.

Rob Larity:

Unique combination of ingredients and we've like spoiled the, the souffle and

Rob Larity:

now it's just gonna collapse and you can't get it back in remotely the same,

Rob Larity:

you know, fashion that it once was.

Jacob Shapiro:

Well, and, and I don't know how much this actually

Jacob Shapiro:

matters, but you know, there used to be a belief in scientific progress.

Jacob Shapiro:

Like these things were seen by society as fundamentally apolitical

Jacob Shapiro:

and as fundamentally virtuous, and they're not seen that way anymore.

Jacob Shapiro:

I mean, we're having real conversations in 2025, the year of our Lord, about

Jacob Shapiro:

measles outbreaks in the United States.

Jacob Shapiro:

You know, I'm, I'm sorry if there are listeners who, who are on the

Jacob Shapiro:

anti-vax thing, but I like, it's one of the few things I, I don't

Jacob Shapiro:

have a whole lot of patience for.

Jacob Shapiro:

Like, we have a fix to this problem.

Jacob Shapiro:

It was fixed.

Jacob Shapiro:

It's a vaccine like I have children.

Jacob Shapiro:

You wanna risk that your kids are gonna get measles.

Jacob Shapiro:

Like this is not some experimental thing.

Jacob Shapiro:

Like we had it.

Jacob Shapiro:

And like even stuff like that is getting demonized.

Jacob Shapiro:

And that's before you get to, okay, we've got all these new types of

Jacob Shapiro:

technologies that we need a whole new regulatory apparatus to even comprehend

Jacob Shapiro:

the things that we're capable of.

Jacob Shapiro:

And.

Jacob Shapiro:

Things that could be very dangerous if they're not handled correctly.

Jacob Shapiro:

Like the speed at which we can do things doesn't mean we should necessarily do them

Jacob Shapiro:

like we should totally have very serious conversations about what this looks like.

Jacob Shapiro:

Uh, but the point just being like in that fragile renaissance Florence metaphor that

Jacob Shapiro:

you're talking about, like there was a time when US society believed in progress

Jacob Shapiro:

and believed in science, and the majority felt good about that and felt good about

Jacob Shapiro:

the United States being the cutting edge.

Jacob Shapiro:

I don't get the sense that that's true anymore.

Jacob Shapiro:

I saw a map about for, for measles vaccination rates in the country,

Jacob Shapiro:

and I was absolutely gobsmacked, um, at the, at the high levels

Jacob Shapiro:

of like unvaccinated rates.

Jacob Shapiro:

Um, for something, for something like measles.

Jacob Shapiro:

So like maybe the, the system doesn't care about what.

Jacob Shapiro:

The rank and file think, but I gotta think that if you have a society that is

Jacob Shapiro:

beginning to show signs of fundamentally doubting the very thing that underpins the

Jacob Shapiro:

advances in the first place, um, I mean maybe that will express itself in a lack

Jacob Shapiro:

of political will to protect this funding.

Jacob Shapiro:

Maybe it does just make it so that foreign researchers are like,

Jacob Shapiro:

well, why would I want to go there?

Jacob Shapiro:

Like, China's the one that has a five point plan that says, we wanna do

Jacob Shapiro:

the absolute cutting edge stuff and we will stop at nothing to make sure

Jacob Shapiro:

that the cutting edge happens here.

Jacob Shapiro:

We'll give you all the tools and all the, the hubs and all of the, everything else

Jacob Shapiro:

just like solve these problems because this is what the future of the planet and

Jacob Shapiro:

of the nation like completely requires.

Jacob Shapiro:

And you couldn't be farther from that in the current US regulatory environment.

Rob Larity:

Well, to tie this into something else that we've talked about in

Rob Larity:

recent months, um, scientists are experts.

Rob Larity:

They're authority figures by definition.

Rob Larity:

'cause they have a secret knowledge.

Rob Larity:

And you know, I kind of made my thesis earlier that.

Rob Larity:

I think a lot of what's happening in the US is really a cultural thing.

Rob Larity:

And we've talked about this many times in the sense of like, it is an

Rob Larity:

anti-authoritarian and anti expert, anyone who, who is perceived to be

Rob Larity:

sort of part of the hierarchy of, uh, authorities and people, you know, elites,

Rob Larity:

they're being torn down 'cause it's a, it's a populous kind of movement.

Rob Larity:

And you can see that like Renaissance Florence only worked and those superstar

Rob Larity:

artists, you know, fancy pants elites, they only got to do what they did because

Rob Larity:

the public was financing the churches that were paying them to paint stuff.

Jacob Shapiro:

Mm-hmm.

Rob Larity:

And you know, same thing for like, you know, mid 16 hundreds

Rob Larity:

Dutch culture, like people really valued what those guys were doing

Rob Larity:

and they were buying what they were doing and that's why it could exist.

Rob Larity:

And, you know, to transport that to today.

Rob Larity:

The public doesn't support, you know, these, these structures doesn't

Rob Larity:

support these, these forms of elites.

Rob Larity:

And you can see that in the gutting of public funding.

Rob Larity:

It's gonna be very difficult to, to maintain that.

Rob Larity:

And that's why, like China is one thing, but I think Europe has an

Rob Larity:

extraordinary opportunity here just because it's more, it's more

Rob Larity:

accessible to most of these people.

Rob Larity:

Like realistically speaking, my Brazilian friends, if they didn't go to Cambridge,

Rob Larity:

they would not be going to China.

Rob Larity:

'cause it's just too weird.

Rob Larity:

It's too like, out of their experience.

Rob Larity:

Um, it's not like China is its own civilization, whereas like

Rob Larity:

coming here to Paris, you know, that's a much easier leap.

Rob Larity:

And I haven't had a chance to really dig into this, but one of the things that's

Rob Larity:

like top on my list is I know the EU has announced some, some significant funding

Rob Larity:

behind, like trying to attract scientists.

Rob Larity:

From abroad and, and, um, like really lean into this.

Rob Larity:

And I don't know if it's, if it's of any size or whatever,

Rob Larity:

but they'd be stupid not to.

Rob Larity:

Um, and, and you know, just thinking, putting this back into the framework

Rob Larity:

of like populism and anti, anti elites, like as I said before,

Rob Larity:

Europe is still pretty in favor of people who know what they're doing.

Rob Larity:

Uh, you know, uh, right wing movements left aside.

Rob Larity:

Like those people aren't running these nations yet.

Rob Larity:

Whereas the US is really struggling with that for reasons we've talked about.

Rob Larity:

And I think that's gonna be a core problem for the US in supporting the sciences.

Rob Larity:

Um, and, and these, these sorts of like research oriented technology

Rob Larity:

development ventures, because to get the people you need to have the

Rob Larity:

structures in place and you need to have the, the general acknowledgement

Rob Larity:

that like, this is a good thing.

Rob Larity:

We like these people.

Rob Larity:

This is good for society to have this.

Rob Larity:

And that's just really lacking, uh, as you point out in, in a

Rob Larity:

way that it wasn't 20 years ago.

Jacob Shapiro:

Yeah.

Jacob Shapiro:

Well, maybe two things to, to close out on.

Jacob Shapiro:

There was a, I dunno if you saw this op-ed by Kyle Chan in the New

Jacob Shapiro:

York Times, which was really good.

Jacob Shapiro:

Um, and it was about China sort of dominating things like high-end

Jacob Shapiro:

manufacturing cars, chips, MRI machines, commercial jets.

Jacob Shapiro:

He makes the very spicy take that the battle for AI supremacy, if we continue

Jacob Shapiro:

on the current trajectory, will not be fought between the United States and

Jacob Shapiro:

China, but between high tech, Chinese cities like Shenzhen and Hong Jo.

Jacob Shapiro:

Like it's not, it's not about us versus China.

Jacob Shapiro:

It's actually probably about like Chinese provinces and cities and

Jacob Shapiro:

like development hubs themselves.

Jacob Shapiro:

Um, and Kaiser quo, who's somebody that I really respect, um, Seneca podcast, if tho

Jacob Shapiro:

for those of you who haven't sort of, uh, discovered him, wrote, not a rejoinder,

Jacob Shapiro:

but actually sort of a meaningful engagement with Kyle Chan's piece.

Jacob Shapiro:

And I, he had a really great corrective.

Jacob Shapiro:

He, um, I. I'll actually read something that he, he said here, he doesn't, he, he

Jacob Shapiro:

says he doesn't, uh, dispute that China's poised to dominate in many of these areas,

Jacob Shapiro:

but he cautions against overstating the coherence or inevitability of China's rise

Jacob Shapiro:

or the permanence of America's decline.

Jacob Shapiro:

Um, he doesn't say this out of patriotic sentiment or triumph as nostalgia.

Jacob Shapiro:

Rather, he believes that his historical outcomes are rarely

Jacob Shapiro:

as clean as the Chinese century versus the American century.

Jacob Shapiro:

And much will hinge on whether either country can summon the political will

Jacob Shapiro:

and institutional capacity, um, to adapt to the scale of the China, uh, to

Jacob Shapiro:

the, uh, to the scale of the challenge.

Jacob Shapiro:

China is formidable, but not infallible.

Jacob Shapiro:

The United States is reeling but not terminal.

Jacob Shapiro:

I thought that was like a really good way of encapsulating some of these things.

Jacob Shapiro:

On the flip side of this, there was an article in the Wall Street Journal this

Jacob Shapiro:

week about, um, a bunch of data centers that were gonna go up in West Virginia

Jacob Shapiro:

actually about a, a law that the West Virginia legislation was trying to pass.

Jacob Shapiro:

Uh, to allow the use of natural gas and coal to power

Jacob Shapiro:

AI projects in West Virginia.

Jacob Shapiro:

And we are talking Podunk, West Virginia, some of the most impoverished

Jacob Shapiro:

places in the entire country.

Jacob Shapiro:

This is coal country.

Jacob Shapiro:

It got left behind.

Jacob Shapiro:

Nobody took care of them.

Jacob Shapiro:

Uh, it's absolutely, it's a beautiful part of the country.

Jacob Shapiro:

I've spent a lot of time actually like hiking and traveling

Jacob Shapiro:

in this part of the country.

Jacob Shapiro:

'cause um, I had some family like in this, in this neck of the woods, no longer.

Jacob Shapiro:

But, you know, I've spent time in this part of the country, even though it's

Jacob Shapiro:

beautiful, it's poor, it's impoverished.

Jacob Shapiro:

And the Wall Street Journal article was all about how the locals are saying,

Jacob Shapiro:

actually, we don't want any of that.

Jacob Shapiro:

We don't want any data centers built anywhere near here.

Jacob Shapiro:

And on the one hand I'm like, okay, I get it.

Jacob Shapiro:

You don't wanna ruin the pristine, you know, rivers and the hiking and

Jacob Shapiro:

the mountains and things like that.

Jacob Shapiro:

But on the other hand, you guys are poor.

Jacob Shapiro:

Your GDP per capita relative to the national average, terrible,

Jacob Shapiro:

your life expense, life expectancy relative to the national average.

Jacob Shapiro:

Terrible.

Jacob Shapiro:

And you don't want the shiny tech money that's coming in and has discovered

Jacob Shapiro:

this beautiful part of the country.

Jacob Shapiro:

It is like, ah, we finally have something we can use all

Jacob Shapiro:

this coal and natural gas for.

Jacob Shapiro:

Why don't you guys become the center of an AI renaissance inside the United States

Jacob Shapiro:

And the the poor impoverished residents are telling the Wall Street Journal.

Jacob Shapiro:

No way.

Jacob Shapiro:

Get off my lawn.

Jacob Shapiro:

I don't want this money.

Jacob Shapiro:

I want my poverty.

Jacob Shapiro:

Uh, along with, you know, being able to hear the crickets, which I get it.

Jacob Shapiro:

I want to hear the crickets too.

Jacob Shapiro:

I talked on the last podcast about how depressing it is that we killed

Jacob Shapiro:

all the fireflies in New Orleans as we were trying to wipe out malaria.

Jacob Shapiro:

Like, I get it.

Jacob Shapiro:

But you can sort of have both.

Jacob Shapiro:

And I, I'm, I'm like a little bit tongue in cheek, but my point is just, you

Jacob Shapiro:

know, it's not the biotech example, but this is an impoverished area that has

Jacob Shapiro:

a resource that could be critical to a boom in an industry that is going from

Jacob Shapiro:

strength to strength, AI and data centers and information economy and everything.

Jacob Shapiro:

And it's like, nah, actually we're good.

Jacob Shapiro:

We're good with where we're at.

Jacob Shapiro:

Like, I, I, I feel like I see that mentality.

Jacob Shapiro:

Everywhere in the United States economy, in the United States culture, in the,

Jacob Shapiro:

you know, the, the gravity that the past has make America great again.

Jacob Shapiro:

Let's go back to the way that things were before.

Jacob Shapiro:

Like, I don't know, like there, there is just something in that, that I

Jacob Shapiro:

have a hard time engaging with and which makes, when, which is starting

Jacob Shapiro:

to color some of these deeper dives into things like AI and biotech.

Jacob Shapiro:

Um, in the current context, which it's not the fault of the current administration.

Jacob Shapiro:

The current administration is just, I think, a reflection

Jacob Shapiro:

of this cultural change.

Jacob Shapiro:

And with its disjointed policy is accelerating some of these trends.

Jacob Shapiro:

Um, but it's, it's hard to be optimistic in some areas about the United States

Jacob Shapiro:

when this is the cultural push.

Jacob Shapiro:

Am am I being, I don't know.

Jacob Shapiro:

Is that too much?

Jacob Shapiro:

I, I'm, I guess I'm feeling glum today.

Rob Larity:

No, I think it, it hits, hits it on the head, frankly.

Rob Larity:

'cause and tying this into China, um, I think it's a matter of coherence.

Rob Larity:

Like when I think about what we're really doing.

Rob Larity:

For clients or from an investment standpoint.

Rob Larity:

So much of it is trying to find where in the world is there the coherence

Rob Larity:

of action and the uni unity of action to, to do big things and to build

Rob Larity:

things and, and to develop and to grow.

Rob Larity:

And that's, that's rare.

Rob Larity:

And, and in the United States, I think in many ways that's now

Rob Larity:

breaking down in many places.

Rob Larity:

Like NIMBY is a form of lack of coherence.

Rob Larity:

It's atomization of interests that will not work together, even

Rob Larity:

though it's probably in the greater good to build that data center.

Rob Larity:

You have friction.

Rob Larity:

And, and this is not to look at China with rose tinted glasses because

Rob Larity:

you know, the normal state of China is one of high friction and lack

Rob Larity:

of coherence and warring states.

Rob Larity:

And one of the things I worry about is like, if Xi Jinping dies tomorrow of a

Rob Larity:

heart attack, I. What the hell happens?

Rob Larity:

Do you enter something like, just look, one of the things that terrifies me, and I

Rob Larity:

don't think anyone's really talking about this, I haven't seen it, are these stories

Rob Larity:

of, um, I dunno if you've seen this, but uh, Chinese local governments are

Rob Larity:

kidnapping executives who come from other states and, and like basically holding,

Rob Larity:

like blackmailing them, holding them ransom 'cause they're so cash strapped.

Rob Larity:

That is a major red flag to me.

Rob Larity:

And maybe it's just, it's anecdotal.

Rob Larity:

Maybe it's not big, but that's the sort of thing you should be looking at if

Rob Larity:

you want to make the bear case on China is that without the sort of coherence

Rob Larity:

of 10% growth, which was driven by the factor, you know, the treadmill, the hill

Rob Larity:

factors that we've talked about, does that coherence break down into atomization

Rob Larity:

and they just can't get anything done.

Rob Larity:

Um, there's no real sign of that yet, but that's the risk on the Chinese side.

Rob Larity:

And it's not a. Tail risk.

Rob Larity:

It's a real, like significant, like that's the bear case and

Rob Larity:

it's worth taking very seriously.

Rob Larity:

Um, and in the US you have the bear case that you pointed out, which I

Rob Larity:

think paralysis, inability to build.

Rob Larity:

Like that's why software has been so successful and everything else has

Rob Larity:

not because software you can just spin up a server and you know, AWS

Rob Larity:

la la land and no one can stop you.

Rob Larity:

Um, it's a lot harder to do that with physical things out in, out in space.

Rob Larity:

Um, so he, God that's like pretty negative on both places.

Jacob Shapiro:

It is, it is negative on both places, which actually underscores.

Jacob Shapiro:

I, I had a question at an event I did a couple weeks ago where somebody asked

Jacob Shapiro:

me, who wins in the US China trade war?

Jacob Shapiro:

And we've said this on the podcast a couple different times and had guests

Jacob Shapiro:

who brought data to back this up.

Jacob Shapiro:

Nobody wins.

Jacob Shapiro:

There are no winners in what's happening right now.

Jacob Shapiro:

So instead of focusing on the things that could actually make life better,

Jacob Shapiro:

we are now focusing on recreating things so that we can have national,

Jacob Shapiro:

um, you know, self-sufficiency in some areas, and we're using these different

Jacob Shapiro:

things as leverage against each other and thinking about what this means

Jacob Shapiro:

from a national power perspective.

Jacob Shapiro:

You can see this in how, I mean, look at how the tech community in the United

Jacob Shapiro:

States has basically just morphed into a defense tech play and has allied

Jacob Shapiro:

itself with, um, you know, uh, with a really defense oriented, like, protect

Jacob Shapiro:

oriented environment, rather than pushing the boundaries of what's new.

Jacob Shapiro:

Um, I think you can sort of see that all over the place.

Jacob Shapiro:

And the, and the depressing thing of what you're saying is, well, what if in

Jacob Shapiro:

fighting each other and in the great power competition, there can be no florences.

Jacob Shapiro:

There can't be a Florence anywhere if everybody is thinking is watching

Jacob Shapiro:

their back and thinking about how some other country is, is gonna attack them.

Jacob Shapiro:

Um, and I think that was one of the nice things about Kaiser's rejoinder

Jacob Shapiro:

to that Kyle, that Kyle Chan article reminding us that, okay, like we're

Jacob Shapiro:

sitting here in the United States.

Jacob Shapiro:

I know West Virginia, I've been to West Virginia.

Jacob Shapiro:

I can read that Wall Street Journal article and make

Jacob Shapiro:

the jokes that I just made.

Jacob Shapiro:

I bet there's a Chinese version of me who can do the same thing in China and can,

Jacob Shapiro:

you know, think about, oh, well we got these grand plans, but I can't, I mean,

Jacob Shapiro:

China had a real problem in getting people to take vaccines around COVID-19, right?

Jacob Shapiro:

Like, so I'm talking about vaccine hesitancy here.

Jacob Shapiro:

Just because, uh, there's a dictatorship in China doesn't mean that the

Jacob Shapiro:

average Chinese person wants to take a vaccine any more than a American

Jacob Shapiro:

citizen wants to take a vaccine.

Jacob Shapiro:

So, um, yeah, I don't know.

Jacob Shapiro:

Maybe you should tell your Brazilian friends to go back to Brazil.

Jacob Shapiro:

That comes with its own, uh, problems.

Jacob Shapiro:

So,

Rob Larity:

well, I guess that that's the bear case to everything that we're doing.

Rob Larity:

I, I've been reading some books about, so, uh.

Rob Larity:

This book by Eric Klein, I just read 1177 bc. Did you ever, did you hear about him?

Rob Larity:

No, no.

Rob Larity:

He wrote one called 1177 BC and then one called after 1177 bc But this is about

Rob Larity:

the collapse of the Bronze Age, uh, civilizations and sort of what happened.

Rob Larity:

And, you know, they used to call it the, the original Dark Age.

Rob Larity:

Basically there was climate problems, mass migration that destabilized societies,

Rob Larity:

which led to warfare and agricultural, you know, problems, which led to costs.

Rob Larity:

And the takeaway in his book after 1177 BC is just like, nobody won.

Rob Larity:

Like, yeah, there were like, the Venetians did relatively better and

Rob Larity:

the Creon did relatively better, in part because they were more mobile

Rob Larity:

and sort of how they could do things, which is a separate discussion, but

Rob Larity:

like, it just sucked for everybody.

Rob Larity:

Everyone did absolutely worse off than they would've otherwise.

Rob Larity:

And that's like the negative scenario of what could potentially be in our future.

Rob Larity:

Like, I hope not.

Rob Larity:

I hope we're in a situation where we're arguing over who gets all

Rob Larity:

the new Alzheimer's treatments and they won't share with each other.

Rob Larity:

But it's not unthinkable to think like, yeah, maybe just no one wins.

Rob Larity:

And it's just, you know, God going into a dark place with this.

Rob Larity:

Yep.

Rob Larity:

With this one.

Rob Larity:

But

Jacob Shapiro:

our podcast title, it sucks for everybody.

Jacob Shapiro:

Nice chatting with all of you.

Jacob Shapiro:

We will see you in two weeks with our latest and greatest.

Jacob Shapiro:

Yeah.

Jacob Shapiro:

Anyway.

Jacob Shapiro:

Um, well, no, it's, it's important to think about the, it's important

Jacob Shapiro:

to think about the downside.

Jacob Shapiro:

Okay, well Rob, I, let's commit to each other that we'll

Jacob Shapiro:

come back here in two weeks.

Jacob Shapiro:

Uh, and let's try and argue the opposite, or let's see if there's any optimism

Jacob Shapiro:

that we can find at some of these things.

Jacob Shapiro:

'cause I think that that's the other thing about the volatility spiral

Jacob Shapiro:

it, uh, I said this actually on another podcast yesterday that I did.

Jacob Shapiro:

Somebody asked me what, uh, what I've been focusing on right now in

Jacob Shapiro:

my honest answer was I haven't felt like I could focus for three months.

Jacob Shapiro:

Um, it used to be that, okay, I spent the first couple hours of

Jacob Shapiro:

my day getting on top of, okay, here's what's going on in the world.

Jacob Shapiro:

And, you know, I'd pour myself a cup of coffee, maybe two, and by 10 o'clock I'd

Jacob Shapiro:

be like, okay, like I have a pretty good, my finger's on the pulse of the world.

Jacob Shapiro:

I can go do some deep research.

Jacob Shapiro:

I haven't been able to do that for three months because just keeping your finger

Jacob Shapiro:

on the pulse of what's going on, like is a five to seven hour job now, where it used

Jacob Shapiro:

to be a two to three hour job for somebody who does this for a living and has been

Jacob Shapiro:

doing it for a living for like 10 years.

Jacob Shapiro:

Um.

Jacob Shapiro:

Which makes it harder to like stay focused on the things that are optimistic.

Jacob Shapiro:

'cause you're not thinking about the bigger trends.

Jacob Shapiro:

You're just having to deal with all of this.

Jacob Shapiro:

Um, and, and it's not just, it's not new things.

Jacob Shapiro:

It's like, okay, one day it's this, then it's 180 degree turn, then oh, another

Jacob Shapiro:

360 turn then oh, 90 degree angle.

Jacob Shapiro:

Let's go this direction.

Jacob Shapiro:

And it's sort of the same thing over and over again.

Jacob Shapiro:

And the trend lines just kind of stays, uh, stays in the same place.

Jacob Shapiro:

So anyway,

Rob Larity:

well, the last time we were in a volatility cycle, I think

Rob Larity:

people said some of the same things about these new motor cars zipping

Rob Larity:

around at these unheard speeds.

Rob Larity:

And, you know, my God, I can't even keep up with the news and war

Rob Larity:

here and terrorist bombings there.

Rob Larity:

And, you know, there's some element of of that that always happens

Rob Larity:

in these things like volatility spirals are also very good.

Rob Larity:

I think that's the hardest thing is like, it's, it is so easy to

Rob Larity:

say the doom and gloom and, oh, 1177 BC and everyone's screwed.

Rob Larity:

Like there's an equally and probably more valid in terms of probability

Rob Larity:

scenario, which is the future's so bright, I gotta wear shades.

Rob Larity:

And like the volatility spiral swings both ways and it'll be both at the same time.

Rob Larity:

There's gonna be countries that are gonna be absolutely demolished by

Rob Larity:

all this stuff going on, and we're already seeing so much of this.

Rob Larity:

And at the same time, there's gonna be such incredible things coming out of this.

Rob Larity:

I, I think, and you can see some of that too, like it's, it's hard

Rob Larity:

to have a nuanced and complex view of the world, but, and that doesn't

Rob Larity:

make for good podcast listening 'cause people just want kind of a

Rob Larity:

relatively straightforward narrative.

Rob Larity:

But both those things can happen simultaneously and you know,

Rob Larity:

that's, that's the reality of it.

Rob Larity:

So yeah, we can talk about the future.

Rob Larity:

So bright, I gotta wear shades.

Rob Larity:

Side of things next time, just to even it out, but

Jacob Shapiro:

alright, well, I'll hold you to it.

Jacob Shapiro:

We'll go from there.

Jacob Shapiro:

Thank you so much for listening to the Jacob Shapiro podcast.

Jacob Shapiro:

Uh, this show is produced and edited by Jacob Mian, and it's

Jacob Shapiro:

in, in many ways, the Jacob Show.

Jacob Shapiro:

Um, if you enjoyed today's episode, please don't forget to subscribe.

Jacob Shapiro:

Rate or leave a review takes just a couple seconds of your time, but it

Jacob Shapiro:

really helps us also share with a friend.

Jacob Shapiro:

If you're interested in learning more about hiring me to speak at your

Jacob Shapiro:

event, or if you wanna learn more about the wealth management services

Jacob Shapiro:

that, uh, I offer through bespoke or at cognitive investments, you can find

Jacob Shapiro:

more information@jacobshapiro.com.

Jacob Shapiro:

You can also write to me directly at jacob@jacobshapiro.com.

Jacob Shapiro:

I'm also on, on X for now with the handle.

Jacob Shapiro:

Jacob Shap.

Jacob Shapiro:

That's Jacob, SHAP.

Jacob Shapiro:

No DATs dashes or anything else, but I'm not hard to find.

Jacob Shapiro:

Um, see you out there.