You know, there's also just a such a huge mental health component.
Speaker BSo we're talking about 40 years ago.
Speaker AKnowledge is power.
Speaker ASo when a woman is going into her doctor and she's talking to her GP or her gynecologist and is, you know, in the throes of menopause and.
Speaker BPerimenopause, yet they have natural hormones back at the right dose and type, and they are transformed.
Speaker BYou know, we're putting people in these chemical straight jackets, giving them highly toxic drugs without thinking about safe hormones.
Speaker AWith perimenopause and menopause, so many women, and I know, I feel included too.
Speaker AYou know, do we just feel like we've lost ourselves?
Speaker AWe're like, who are we?
Speaker AYou know, what is this?
Speaker BIf I had a rash on my face, you would look at me and go, oh, Louise, that looks painful.
Speaker BHave you seen a dermatologist?
Speaker BWhereas if I tell you I feel so joyless and flat and low, you might go, oh, it's a bit awkward now.
Speaker BI don't quite know what to say, you know.
Speaker AOkay, ladies, this is not your mom's menopause.
Speaker AToday we're diving into the real, raw and revolutionary truth about hormones, perimenopause, and what the heck is actually happening to our bodies in midlife.
Speaker AWith one of the world's leading voices on women's health.
Speaker AMy guest today is Dr.
Speaker ALouise Newson, a world renowned menopause specialist, best selling author and founder of the Newson Health Menopause and Center.
Speaker AShe's the force behind some of the most important research and policy changes in women's health care.
Speaker AAnd her work has empowered millions of women to reclaim their health, their hormones and their confidence.
Speaker ASo if you've ever been told it's just anxiety, or if you've ever left a doctor's office feeling more confused than when you walked in, or.
Speaker AOr if you've ever looked in the mirror and wondered who that tired, brain foggy, bloated woman is staring back at you.
Speaker AThis conversation is for you.
Speaker AGet ready to feel informed, fired up and seen.
Speaker ALet's get into it.
Speaker AWelcome, Dr.
Speaker ANewson.
Speaker AIt's wonderful to have you here today.
Speaker BOh, well, thank you for inviting me.
Speaker BIt's a real honor to be here.
Speaker AOh, I'm just so excited.
Speaker AI appreciate you.
Speaker AFor those who don't know, Dr.
Speaker ALouise Newson is in London.
Speaker ASo we are excited to have you on and I just want to dive right in because I think that there are so many misconceptions and so many, you know, things that we've heard about menopause, perimenopause, the hormones, everything.
Speaker AAnd women are really not informed about their bodies.
Speaker ASo, you know, and so many of us, when we go to the doctor, we're either misdiagnosed or we're dismissed by our doctors, especially during perimenopause.
Speaker ASo, so what do you.
Speaker AWhy do you think that the medical system is failing women in this way?
Speaker BYou're right, though, it's due a lot to misunderstanding.
Speaker BAnd it's not just misunderstanding by women, but healthcare professionals as well.
Speaker BAnd the problem is, and even now, if you ask someone what menopause means, they'll tell you it's hot flashes.
Speaker BIt's a natural transition that women go through, which absolutely it is.
Speaker BAnd it isn't because it's far more than hot flashes.
Speaker BIt may be natural, but it doesn't mean we can't treat it.
Speaker BAnd it's not a transition.
Speaker BIt's not something we will just phase in our lives.
Speaker BSo women have been told wrong information, but so have doctors.
Speaker BYou know, I qualified quite a few years ago in 1994, but I didn't have any formal menopause training.
Speaker BAnd then for many years, in fact decades, people, doctors have been told HRT is dangerous, don't prescribe it for women.
Speaker BSo then they not been learning about menopause because they think there's no treatment which is so wrong on so many levels, which we can talk about.
Speaker BSo this misunderstanding has carried on.
Speaker BAnd then when people are confused, they often go to the wrong sources or they get the wrong information or they speak to the wrong people and then it causes more confusion.
Speaker BSo it's absolute mess.
Speaker BAnd this is a travesty for women because within, amongst all this mess and confusion, women are suffering and they're having health risks as well from not having their hormone health addressed properly.
Speaker AAnd you know, that is.
Speaker ASo the hot button topic right now are HTRTs.
Speaker AI mean, there's so much confusion going around about hormone replacement therapy.
Speaker AShould I do it, should I not do it?
Speaker AWhat are my risks?
Speaker ALike, am I going to be at a higher risk for breast cancer?
Speaker AYou know, that's a lot of concern on women's minds.
Speaker ASo can we kind of break that down and kind of dispel some of the untruths that are associated with hrts?
Speaker AAnd is it for everybody?
Speaker BYeah.
Speaker BSo I think before I talk about hrt, it's worth talking about menopause and hormones because what happens when we don't have those hormones?
Speaker BIt can affect our body in so many ways.
Speaker BBut when we talk about hormones, we're only talking about three hormones.
Speaker BWe've got hundreds of hormones in our body, and they are chemical messengers that go into our blood and affect every.
Speaker BEvery single cellular process.
Speaker BSo every cell responds to hormones, so they are biologically active, natural substances.
Speaker BSo when we talk about estrogen, we talk about estradiol, which is the most important form of estrogen, progesterone, and testosterone as well, which is an important female hormone.
Speaker BSo when we give hormone replacement therapy, all we're thinking about is those three hormones.
Speaker BAnd there are different doses, there are different types of.
Speaker BAll we're doing is replacing the hormones.
Speaker BAnd we do this for two reasons, really.
Speaker BThe first is to improve symptoms.
Speaker BBecause there are a myriad of symptoms that women who are menopausal, perimenopausal can experience, mainly affecting our brains, actually.
Speaker BThe brain fog, the low mood, the anxiety, the poor sleep, the irritability, the feeling quite joyless and flat.
Speaker BSo we can improve the way people feel with hormones, which actually is not a bad thing if women feel better.
Speaker BBut more importantly for me as a physician, it's about improving our future health.
Speaker BBecause these hormones work on every cell.
Speaker BSo therefore, in every organ of our body.
Speaker BThey help reduce inflammation, they help keep our organs.
Speaker BSo our heart, our bones, our brains work better.
Speaker BSo we know that when people have replacement hormones at the right dose and type for.
Speaker BFor them, their future health improves.
Speaker BThey have a lower risk of heart disease, a lower risk of osteoporosis, a lower risk of type 2 diabetes, Parkinson's, dementia, other conditions as well.
Speaker BAnd that's really important that we think about it beyond just a treatment for a few hot flushes.
Speaker ASo I'm glad you're kind of laying it all out, because I think people think hormone replacement therapy, and they think it's an all for one and a one for all.
Speaker AAnd there's one treatment, and.
Speaker ABut really there's varying levels of these different hormones.
Speaker AAnd depending on what the needs are for your body and for your stage, that's like.
Speaker AThat would be the hormone.
Speaker AIt's very individualized.
Speaker BIt's completely individualized.
Speaker BAnd it's also really important.
Speaker BYou know, when I talk about giving hormones to women who are perimenopausal and menopausal, these are a natural.
Speaker BThey're natural in that they are a complete replica of the hormones we have when we're younger, when I talk about prescribing hormones as part of contraception, these are all synthetic, They've been chemically altered.
Speaker BYet no one, across the world seems to worry about contraception, which by the way has more risks because it's not a natural replica.
Speaker BBut these are natural hormones.
Speaker BWe have had synthetic hormones in the past.
Speaker BAnd in fact, the HRT that everyone is concerned about from the whi, the Women's Health Initiative study was made from pregnant horses urine.
Speaker BLike, we don't use that.
Speaker BYou could argue that pregnant horses urine is natural, but it's not natural for women to have.
Speaker BSo, you know, HRT has moved on, but when we talk about it, we have to be very clear and particular whether it's a natural or synthetic hormone.
Speaker BAnd like you say the type and the dose because if you're not on the right dose, if you're not on the right type, so say you're testosterone deficient and you're only having estradiol, you can have all the estrogen you like, but it's not going to help those testosterone depleted cells.
Speaker BSo that's where it's really crucially important that everybody is seen as an individual and the dose and type is individualized for them.
Speaker ANow, as far as the health risks go, who are the women that should not be taking hrt?
Speaker AAre they the women that have already had breast cancer or that are at risk for breast cancer and other female cancers due to family history?
Speaker BSo as a, as a doctor, my role really is to help women make the right decisions for them and to share any uncertainty, to talk about shared decision making.
Speaker BSo there is no one who absolutely can't have anything.
Speaker BYou know, that's the most important thing is that there's never been a study to show that people are going to literally die overnight by having their own hormones back.
Speaker BSo then we look at the evidence, but sometimes there's lack of evidence.
Speaker BSo if we answer the easy things first, lots of people are told they can't have HRT because they've had a history of a clot, for example, or they have migraine or there's someone in their family has got a history of clot.
Speaker BNow older types of hormones and tablet oestrogen do contain a small risk of clot associated with them.
Speaker BBut the natural hormones, the estrogen through the skin, the estradiol, the natural progesterone, natural testosterone and do not have a risk of clot.
Speaker BAnd then people worry about the cancer risk.
Speaker BNow the breast cancer risk has been associated with the synthetic progestogens that are in contraception.
Speaker BBut even then the WHI study didn't show it was statistically significant.
Speaker BBut they are the only studies that show there was a risk with breast cancer.
Speaker BSo when we give the natural hormones, it's unlikely to be increasing our risk of cancer, because younger people are less at risk of cancer than older people who don't have hormones naturally, of course.
Speaker BSo people who have a family history of breast cancer or they've had a history of most types of cancer, they can still usually safely have hormones.
Speaker BThe big uncertainty is women who've had breast cancer.
Speaker BBut there are different types, there are different grades of breast cancer, and there are different times.
Speaker BSince people have had breast cancer cancer, we look at the receptor status of breast cancer.
Speaker BSo is it oestrogen receptor positive or negative?
Speaker BAnd firstly, it's worth explaining that an estrogen receptor positive breast cancer does not mean it's been caused by oestrogen.
Speaker BIt means it's got oestrogen receptors on it.
Speaker BWe have estrogen receptors on every cell in our body.
Speaker BIf a cancer becomes mutated, then there's going to lose some of its receptor status and become estrogen receptor negative.
Speaker BBut we don't know whether giving oestrogen to women with estrogen positive breast cancers or oestrogen receptor positive breast cancers increases their risk of a recurrence or a worse outcome going forwards.
Speaker BSome studies have shown that women do better after having hrt, but the studies haven't been set up in the right way for the right length of time.
Speaker BSo then we're dealing with uncertainty now.
Speaker BThere are different types of hormones, like I've said.
Speaker BSome studies have shown that women who have testosterone after breast cancer have a better outcome, a less instance of recurrence, and less incidence of problems going forwards with their breast cancer.
Speaker BWe also know that women who take hrt, whether they've had breast cancer or not, as I've said, have a lower risk of osteoporosis and heart disease and feel better.
Speaker BSo we see people in our clinic who have had breast cancer.
Speaker BSome of them might have been 10, 20 years ago.
Speaker BThey've been told they can never have hormones, yet they've got osteoporosis, they've given up their job, they're feeling so awful, They've tried every supplement under the sun, they've been on antidepressants, they've been on alternatives.
Speaker BAnd they say, do you know what, Dr.
Speaker BNewson?
Speaker BIt might increase my risk, but I know what it's like to have had breast cancer and I'll forego that risk.
Speaker BIt means my bones will be stronger if it means that I'll be a happier person, if it means I can reduce some of these antidepressants and that's what I said at the beginning.
Speaker BIt's an individualized choice, really.
Speaker BI feel really sad when people are just told, no, you can never have HRT because there's no evidence that it's absolutely harmful.
Speaker BAnd even if we did have that evidence, we still know it's beneficially as well.
Speaker BAnd that's where it comes to a very individualized consultations.
Speaker AIn the case that a woman, let's say she is not able to take an HRT due to, you know, hormone receptive breast cancer, is there a natural supplement that would alleviate some of the symptoms or help through menopause?
Speaker BSo we need to think about when we talk about a natural supplement, because hormones are natural.
Speaker BOf course, there are lots of things that are marketed as natural, but they can be risky.
Speaker BYou know, there's lots of things that grow in my garden that are natural, but they could be poisonous if I ingest them.
Speaker BSo we have to be careful what we take.
Speaker BWhen we think about supplements for menopause, a lot of them are marketed to vulnerable women.
Speaker BAnd so we have to think about, firstly, are they going to help symptoms and secondly, are they going to help future health?
Speaker BSome might improve symptoms, so things like sage might improve some hot flushes and sweats.
Speaker BSome of the other drugs that sometimes are prescribed non hormonal drugs might help flushes and sweats, but they very seldom.
Speaker BThere's no evidence often that they're going to improve the brain fog, the fatigue, the muscle and joint pains, the urinary tract infections, for example.
Speaker BBut also it's looking at future health.
Speaker BSo if someone doesn't want to take hormones for whatever reason, then we need to look at how am I going to reduce that person's risk of heart disease, increase their bone strength.
Speaker BSo I might be thinking about vitamin D supplement, I might be thinking about magnesium, or I might be thinking about a probiotic for their future health rather than for their menopause.
Speaker BBecause we need to be thinking about menopause as something that lasts with us forever.
Speaker BSo it's not just a transition because once the hormones are low, they're low forever.
Speaker BSo whether we have symptoms or not, we still have this risk of diseases.
Speaker BAnd so some of people are thinking, oh, I just have a quick fix to help a few symptoms that might last for a short period of time.
Speaker BWell, no, let's think about how we improve our future health in the longer term.
Speaker BAnd working with patients, whether they take hormones or not, we need to be thinking very holistically about keeping healthy and preventing Diseases.
Speaker AI'm so glad you brought that up.
Speaker AThat it isn't just a transition, it is actually a life stage that extends far past that.
Speaker BIndeed.
Speaker ARight.
Speaker AAnd it's something that I think as women, we really need to, you know, grasp and like, really understand that you're really planning for your future health.
Speaker BAnd it's so important because we've been fed all this misinformation, because when you read studies, they'll say, oh, symptoms might only in inverted commas last seven to ten years.
Speaker BSo then a lot of women think, all right, so if I, my last period is when I'm 50, I'll be done by I'm 60 and then I'm through the menopause.
Speaker BAnd I, I was recently in New York and I went out to dinner with some gorgeous ladies and they go, oh, no, I'm through the menopause.
Speaker BIt's like, you're not, you're still alive.
Speaker BHow can you be through it?
Speaker BYou are always going to be menopausal.
Speaker BAnd then they were like, oh, my goodness.
Speaker BWhat you mean I've always got low hormones?
Speaker BIt's like, yep.
Speaker BSo it's a different mindset, but we have to be waking up to it because we're living longer as women, which is great.
Speaker BBut we all want to be healthy, don't we?
Speaker BSo we've got to be thinking about how these lack of hormones have effects on our bodies.
Speaker AAbsolutely.
Speaker AAnd let's talk a little bit about testosterone because that is such a hot button topic.
Speaker AYou know, I think for a lot of women, they think the word testosterone and they're thinking about their partners or their husbands, you know, like, you know, men, this is like a male hormone, but it in fact is not.
Speaker AWomen have quite a bit of testosterone.
Speaker BYeah.
Speaker BAnd it's such a shame, isn't it, that they called it testosterone from the bull's testes, which is where they first extracted it from.
Speaker AOh, wow.
Speaker BIt's real shame.
Speaker BIf they called it anything else, we wouldn't be having this debate.
Speaker BBut what's really interesting is that it's the most biologically active hormone women have.
Speaker BWe have more testosterone than estrogen in our bodies when we're young, when we're in our late teens, early 20s, and then levels start to decline with age.
Speaker BSo from the late 20s, early 30s, our levels decline naturally.
Speaker BSo it's not really a menopause related decline, it's an age related decline.
Speaker BBut about 50% of our testosterone is made in our ovaries.
Speaker BSo those women that have a surgical menopause so they have their ovaries removed at a young age, will reduce and lower their testosterone quicker than other people.
Speaker BBut testosterone works on every cell in our body.
Speaker BIt's made in our brain as well, and it's a very important hormone for the way our brains work.
Speaker BSo people symptoms of testosterone deficiency are often low mood, reduced energy, poor sleep, brain fog, poor concentration, but also headaches, migraines, muscle and joint pains, urinary symptoms, because we have testosterone receptors in our bladder as well.
Speaker BMyriad of symptoms.
Speaker BBut the only studies really that have been done on testosterone in women have been looking at our libido and our sexual function.
Speaker BSo then a lot of menopause societies and some specialists will say, well, we can only give it to women who have hypoactive sexual desire disorder, which basically means they have really awful libido that's giving them severe psychological distress for at least six months.
Speaker BWhich in my mind feels completely barbaric because in medicine we don't watch people suffer for at least six months, we intervene a bit earlier.
Speaker BAnd testosterone isn't just about sexual.
Speaker BOf course it can help people's libido, it can help people with orgasm and sexual desire.
Speaker BBut as women, it's not just a hormone related thing whether we want sex or not.
Speaker AAbsolutely.
Speaker AAnd I'm glad you're bringing that up also because I think sex is a really tough issue at this stage in our lives.
Speaker AYou know, it's not only with the loss of hormones that you lose sometimes the desire to have sex, but it can actually be painful.
Speaker BAbsolutely.
Speaker BAnd this is really important.
Speaker BAnd you know, studies even now show that women are very nervous about talking about sex to their healthcare professional.
Speaker BAnd what's really sad is a lot of healthcare professionals don't want to bring up sex in the consultation.
Speaker BYeah.
Speaker BActually the more I talk about it to patients, the more they say, I'm so pleased we're talking about it because I don't know who else to talk about.
Speaker BAnd symptoms of vaginal dryness, soreness, irritation are the most commonest symptoms that persist in menopause.
Speaker BWe know about 70% of menopausal women have symptoms, symptoms related to vaginal dryness, soreness.
Speaker BYet only about 10% of women receive treatment.
Speaker BAnd HRT can improve symptoms.
Speaker BBut more importantly, vaginal hormones can.
Speaker BVaginal hormones are very low dose given in the vagina, but they can also help urinary symptoms as well.
Speaker BAnd they can be safely used, usually for women who've had breast cancer too.
Speaker BSo even if women don't want to Take hrt, or they take decided that it's not for them, they should still consider vaginal hormones, which can be transformational for sex, but also just for reducing urinary tract infections and cystitis, which are so common in people, especially as they age.
Speaker AAbsolutely.
Speaker AAnd also this phenomenon of vaginal atrophy, which I recently learned about.
Speaker AI mean, the symptoms keep coming, don't they?
Speaker BWell, do you know what they used to call it?
Speaker BVva.
Speaker BSo vulvovaginal atrophy.
Speaker BNow, if you look up the word atrophy in a dictionary, it's actually withering and wasting away.
Speaker BLike, which part of our anatomy really wants to be withering and wasting away?
Speaker BRight.
Speaker BSo if they have changed the nomenclature, so it's gsm, genitourinary syndrome of menopause.
Speaker BBut it's not just menopause.
Speaker BI see a lot of young women who are perimenopausal or women who are just testosterone deficient who have this genitourinary symptoms.
Speaker BSo we need to be really tuned about that as well.
Speaker AAbsolutely.
Speaker AAnd is it possible for somebody, let's say they haven't started hrts yet, they're not doing hormone therapy, but they have gained the weight that sometimes comes with perimenopause and menopause.
Speaker AIs there a way to lose the weight without taking an HRT or before you start taking an hrt?
Speaker BYes, it's a great question.
Speaker BAnd, you know, probably every woman wants or thinks about their weight or wants to lose a bit of weight.
Speaker BI mean, it's just.
Speaker BI don't know, there's something about our genetic profile, probably.
Speaker BBut we know that our metabolism changes with our hormones, especially estradiol and testosterone.
Speaker BThey have direct effects in our brain, which helps our metabolism.
Speaker BAnd our brain has very direct pathways with our liver, but also our pancreas and our glucose metabolism and insulin as well.
Speaker BSo there are so many people.
Speaker BAnd I feel really embarrassed because for many years people would come to me as a GP, a family physician and say, oh, Dr.
Speaker BNewson, I put on all this weight and my lifestyle hasn't changed.
Speaker BAnd I'd look at them and go, really?
Speaker BSurely you're sneaking in some extra whatever.
Speaker BBut actually, no, their metabolism is changing.
Speaker BAnd also the way they respond, the way they have some insulin resistance, can it increase quite early on?
Speaker BAnd often they think they're not perimenopausal or they think they might not have testosterone deficiency, but they probably have.
Speaker BAnd we know that when people have replacement hormones, their sugar levels can improve and their metabolism can improve.
Speaker BWe know there's like a massive thing, isn't there, for all the GLP1s, which I don't actually prescribe, because I think it's a lot better if you can look at the underlying cause.
Speaker BSo a lot of people actually have maybe some PMS or premenstrual syndrome or pmdd, premenstrual dysphoric disorder.
Speaker BSo they might find it's those week or days before their periods, they have sugar cravings, they're eating more, they're having more comfort foods because they're feeling lower in their mood and that will change their metabolism because their estradiol is dropping before their periods.
Speaker BSo they might not be officially perimenopausal, but they will have hormonal changes.
Speaker BSo we need to be thinking about these hormonal changes and helping them replace them with natural hormones, which cannot often improve.
Speaker BA lot of people are given synthetic hormones when they're younger, so contraception, because doctors will often say, well, this will smooth out your hormones.
Speaker BWell, it won't.
Speaker BIt will block all your hormones working.
Speaker BSo a lot of people on contraception tend to put on weight or they find it harder to build muscle, harder to exercise.
Speaker BSo we need to be really, I think, thinking about hormones, thinking about lifestyle before we do anything else about weight.
Speaker ASo if somebody is taking the GLP1s and the Ozempic, is that going to have an effect on their menopause, their perimenopause?
Speaker AAre the two.
Speaker ADo they go hand in hand?
Speaker BProbably not.
Speaker BI mean, there's very little work.
Speaker BWhen you look, there are some studies that show if people are on GLP1s and HRT, they'll have better weight loss.
Speaker BOne of the concerns, as I'm sure you know, is that when women, or some women who take GLP1s, they will lose fat, but they'll also lose lean muscle mass as well.
Speaker BAnd so without our hormones, we have an increased risk of something called osteosarcopenia, which means loss of muscle and bone density too.
Speaker BIf we have loss of muscles, it often means we're less strong, we're more likely to fall.
Speaker BIf we have our bones are weaker, we're more likely to have osteoporosis.
Speaker BSo we don't want a drug that's going to make that worse for us as well.
Speaker BSo we have to be really careful.
Speaker BThere is a role, I'm sure, for GLP1s for some people, but so many women are taking them as a quick feature fix.
Speaker BAnd I know, like doctors in the UK and probably with you as well, are just going, oh yeah, just try a low dose, just have these.
Speaker BBut they're not treating the underlying problem.
Speaker BAnd in medicine you want to treat the underlying cause.
Speaker BSo it's balancing hormones, obviously, making sure people's thyroid is working well as well.
Speaker BBecause all our hormones work very closely together.
Speaker BThey don't work in isolation.
Speaker AAbsolutely.
Speaker AAnd what are three actionable lifestyle changes that women could make today that would have a positive effect on their health 10 years from now?
Speaker BSo.
Speaker BWell, the most important thing I think is to be really honest with yourself.
Speaker BWe all know what we should do, but sometimes it's hard.
Speaker BI think adding something to your diet is really important.
Speaker BSo increasing the amount of fibre that we have and natural foods that we have, as in food that you could potentially grow in your garden, that you would recognize that hasn't been chemically altered.
Speaker BSo you want the real deal.
Speaker BYou want those fresh strawberries, not strawberry flavored goodness only knows what, because that makes a real difference.
Speaker BI think also finding some exercise that you enjoy.
Speaker BLike we can all do more exercise, but I look at my husband on his exercise bike and if I do more than 20 minutes, it will induce a migraine.
Speaker BI'm very sensitive to migraines, so I circumvent it because I do a lot of yoga instead.
Speaker BAnd he looks at me doing yoga and thinks, oh, that's not real exercise.
Speaker BBut you know what, I'm a lot more flexible than him and my pelvic floor is probably a lot better than his.
Speaker BSo.
Speaker BBut you've got to find something that you enjoy.
Speaker BSo doing exercise, looking at what you're eating and the other thing is really important to look at what you're drinking.
Speaker BSo I mean, I don't drink alcohol.
Speaker BI don't expect everyone to be teetotal, but alcohol has a lot of calories.
Speaker BBut it also can affect our hormones and our metabolism.
Speaker BBut not just alcohol.
Speaker BYou know, go into any store and it's full of brightly colored drinks.
Speaker BLike all these drinks are chemicals in our body.
Speaker BEven if they're low sugar or whatever they're labeled, we should just be drinking water.
Speaker BSo do not be hoodwinked to think that these locale sugar free goodness.
Speaker BOh, what are not affecting our metabolism because they will be.
Speaker BSo looking at what you drink as well as eat and exercise are really important.
Speaker AYou know, there's also just such a huge mental health component with perimenopause and menopause and so many women.
Speaker AAnd I know, I feel included too.
Speaker AYou know, do we just feel like we've lost ourselves.
Speaker AWe're like, who are we?
Speaker AYou know, what is this?
Speaker ASo what advice would you give to women who feel like they've lost themselves and are really struggling with their mental health during this time?
Speaker BMost important thing is, is to recognize it and really think about hormones.
Speaker BSo I was reading a book recently.
Speaker BIt was a book I've read a few years ago, but it's about mental health and hormones and the brain.
Speaker BAnd it was written in the 1980s, so we're talking about 40 years ago.
Speaker BAnd it's showing the role of hormones in our brain, how it helps our brains to grow the cells, to grow the nerves, to grow the connections between the nerves to work well.
Speaker BAnd also it helps other neurotransmitters.
Speaker BSo neurotransmitters and chemicals that send messages from one part of the brain to another.
Speaker BAnd we know about neurotransmitters such as serotonin, our happy hormone, or dopamine, our reward hormone.
Speaker BIf we have low estradiol in our brain, it then has an effect where we have low serotonin and low dopamine so often reduces our mood.
Speaker BWe feel just joyless and flat because we don't have dopamine.
Speaker BSo we could do something that we'd normally enjoy and we're just like, oh, what's the point?
Speaker BPoint?
Speaker BSo if we know why it works, try and treat the underlying cause.
Speaker BSo having the right dose of Estrada will increase our serotonin, increase our dopamine, for example, increase the nerve pathways.
Speaker BSo many women are given antidepressants, and antidepressants will work if people are truly clinically depressed.
Speaker BBut they won't improve the low mood, the anxiety, the feeling of worthlessness and joyless if it's related to hormones.
Speaker BSo we need to be questioning ourselves as women if we think we're depressed and we're being offered hormone.
Speaker BWe've been offered antidepressants, but we feel there might be a hormonal component.
Speaker BSure, you can have the antidepressant, but think about hormones as well.
Speaker BThink about hormones improving our mental health, because they often do.
Speaker BAnd the hormones that really make a difference in, in my vast clinical experience in practices is actually the addition of testosterone.
Speaker BYou know, I see so many women who have been given not just antidepressants, but lithium, olanzapine, electroconvulsive therapy.
Speaker BThere's a vogue over here now that people have ketamine infusions for their so called treatment resistant depression, yet they have natural hormones back at the right dose and type, and they are transformed.
Speaker BWe're putting people in these chemical straitjackets, giving them highly toxic drugs without thinking about safe hormones.
Speaker BSo we need to be helping others as well.
Speaker BBecause sometimes when you have a mental health condition, you can't recognize it in yourself.
Speaker BSo you need your partner, your friend, your work colleague to go, louise, you're not quite the same.
Speaker BYou know, is there something else going on or could it be related to your hormones?
Speaker AYou know, I'm glad you're saying that too, because I opened up my DMs and asked the audience, you know, I said, are there questions that you have?
Speaker AAnd you would be so shocked at how many husbands, boyfriends, partners, reached out to me and said, you know, my wife, my girlfriend, my friend is going through this and I don't know how to help her.
Speaker BIt's really hard.
Speaker BIt's so hard.
Speaker BAnd, and you know what I mean?
Speaker BThis is funny, but it's not funny.
Speaker BBut my husband's a doctor and a few days ago I was, I thought I would just try a different formulation of testosterone because I've been on the same dose for a while and, and I thought, well, I'd just try this gel rather than the cream that I use.
Speaker BAnd over the last three days, I've been sleeping in the day, I've been irritable, I've been tired, I've had joint pain, I've had a three day migraine.
Speaker BAnd my husband just looked at me, went, ugh, are you perimenopausal again?
Speaker BBecause you're just the same as you were eight years ago.
Speaker BAnd I went, oh, do you know what, Paul?
Speaker BI've just changed my dose of hormones.
Speaker BAnd he was like, oh my God, go back to what you were on before.
Speaker BAnd.
Speaker BBut I knew that I'd changed, but he didn't know, but he recognized.
Speaker BBut eight years ago, we had six months of almost hell where I was shouting, it was awful, and he didn't recognize.
Speaker BAnd I wish he had the knowledge he has now because if, you know, a few days, a few weeks, he would have then said, oh, Louise, perhaps, you know, you need to learn a bit more about hormones.
Speaker BAnd it's really hard for partners because, you know, divorce rate increases in the 40s and, you know, I've spoken to so many partners, either male or female partners of women who just say, look, this isn't the person that I fell in love with.
Speaker BBut every time I talk to her, she's irritable, she's flat, she burst into tears, like, what have I done with social Tempered.
Speaker BAnd it's not even.
Speaker BA lot of them obviously, aren't having sex, but they're not having any physical contact.
Speaker BYou know, they just.
Speaker BAnd it's really hard because that woman is often feeling so isolated and so scared, and so it's so hard to conceptualize.
Speaker BAnd it's very different to clinical depression because a lot of women I see, even women who are really in the depths of despair don't want to be like this.
Speaker BThey'll do anything to feel better.
Speaker BWhereas women who are clinically depressed don't have the same insight.
Speaker BThey'll just do whatever.
Speaker BI don't.
Speaker BDon't really care.
Speaker BThese women are petrified of how they're feeling, but they don't know who to talk to.
Speaker BAnd.
Speaker BAnd mental health, I think, is still really difficult.
Speaker BLike, if I had a rash on my face, you would look at me and go, oh, Louise, that looks painful.
Speaker BHave you seen a dermatologist?
Speaker BWhereas if I tell you I feel so joyless and flat and low, you might go, oh, it's a bit awkward now.
Speaker BI don't quite know.
Speaker BYou're what.
Speaker BSo, you know, but we need help.
Speaker BAnd I.
Speaker BAnd it.
Speaker BBut it's pointing people to hormones.
Speaker BAnd, you know, people can still have psychiatric medication if they need it, but they can still have hormones as well.
Speaker BAnd I'm really saddened that psychiatrists are not approaching hormones in a really embrace of inclusive way.
Speaker BThey're just going, oh, no, we don't prescribe hormones.
Speaker BLet's prescribe some more other drugs instead.
Speaker AIt's still.
Speaker AThat's the crazy thing, too, that it's not treated holistically.
Speaker AYou know, the mind, the body and all coming together, and it, like, it would be so much more helpful.
Speaker BYeah, And I think it's getting worse because medicine's very siloed.
Speaker BYou know, you have palpitations and you see a cardiologist, you have urinary tract infections, you'll see a urologist, you have worsening migraines, headaches, you'll see a neurologist.
Speaker BNo one will think, well, what's joining the dots?
Speaker BWhat.
Speaker BWhat.
Speaker BWhat are the hormones in this lady?
Speaker BSo.
Speaker BSo then people are given a heart drug for their palpitations, antibiotics for their urinary tract infections.
Speaker BOften quite horrible drugs for migraines, you know, and so then people are getting side effects, they're getting other drugs.
Speaker BSo, you know, and it's awful.
Speaker BEven if you think about pain, you know, people in menopause are far more likely to have chronic pain.
Speaker BThey're far more likely to prescribe opioids and tramadol, highly addictive drugs that doctors are dishing out like Smarties.
Speaker BBut you ask for some HRT and they'll be going, oh, oh, you sure you want that?
Speaker BThere's risks.
Speaker BIt's madness.
Speaker AOh my gosh, it's absolute madness.
Speaker ASo knowledge is power.
Speaker ASo when a woman is going into her doctor and she's talking to her GP or her gynecologist and is, you know, in the throes of menopause and perimenopause, what should she be telling them or what should she be asking them, you know, if she's feeling dismissed?
Speaker BSo the most important thing is having that knowledge before you go to a consultation.
Speaker BSo, you know, download Balance, the free app that I created.
Speaker BGo to my website, drlowisenewson.co.uk, we've got lots of articles on there.
Speaker BFind something that resonates with you, but make sure it's evidence based information that's not biased as well.
Speaker BI don't do any paid work with pharma, just for complete disclosure.
Speaker BMake sure that you're comfortable in your decision and then be really, you know, you might have to write things down.
Speaker BIt can be quite intimidating going to see a doctor, but then just say, look, I think or I know that I'm menopausal or perimenopausal, I would like to try some hormones and then think about, you know, if people are scared or they're not prescribing, then I think we should be asking as patients, why are you not prescribing me an evidence based treatment?
Speaker BWhy are you denying me a treatment that will reduce my risk of a heart attack and osteoporosis as well as help me feel better?
Speaker BBecause I think the only way we can change the conversation quickly is by women leading the consult, the consultations and conversations actually.
Speaker BBut you have to have the knowledge first.
Speaker BBut, you know, share your knowledge, go with someone else, go with a friend, go with a partner and make sure that you make the right decisions for you.
Speaker BYou know, we're all different, we're allowed to choose different things in life and we can choose about, you know, what we do with our hormonal health, also knowing that you can change your mind at any time.
Speaker BSo if you decide you want to stop your hormones or you don't want them now, but you might want them in a few years time, that's fine as well.
Speaker BIt's not a decision that you've, you know, drawn out in black and white and you can't change.
Speaker AThat's good to know.
Speaker AAnd are there any supplements that we should all have in our medicine cabinet that are not only effective but, you know, would be something that would carry us through?
Speaker BYeah, So I would actually, as a rule of thumb, I would.
Speaker BAnything that's labeled menopause, I would.
Speaker BI just put in the bin because it's often marketing.
Speaker BWe should all be taking vitamin D.
Speaker BActually.
Speaker BVitamin D is really good for our bone health and reduces inflammation.
Speaker BAnd then it's very individualized.
Speaker BActually.
Speaker BSome women choose to take probiotic or fish oil, but I wouldn't take anything just because you're menopausal.
Speaker AAnd the connection between menopause and heart health is something that I think a lot of women overlook and they also go hand in hand.
Speaker ASo keep up.
Speaker AI would.
Speaker AI mean, if you would agree to keep, you know, the heart check and really paying attention to that as well, because I think that's something that's very overlooked and that's the number one killer of women.
Speaker BYeah.
Speaker BSo heart disease and dementia, number one killers globally.
Speaker BIn women.
Speaker BWe're five times more likely to have a heart attack when we're menopausal if we don't have hormones.
Speaker BReally important that we look at our blood pressure, you know, we make sure that our hearts are as healthy as possible as we age.
Speaker BDefinitely, definitely.
Speaker AAnd what does thriving in midlife look to you?
Speaker BJust being the best version of yourself.
Speaker BI think the whole midlife is a.
Speaker BIs a difficult word, isn't it?
Speaker BBecause when's the middle of our lives, like, who knows?
Speaker BWe haven't got a crystal ball.
Speaker BBut I think, you know, I'm quite a macabre person.
Speaker BSadly, my father died when I was very young and every day could be our last.
Speaker BSo we've got to make the most of it.
Speaker BWe can't be thinking, well, I'll do this in the future, or maybe I'll take up exercise in future, or maybe I'll change my diet, or maybe I'll change my job or whatever, or think about hormones in the future.
Speaker BWe've got to put ourselves first.
Speaker BAnd I think one of the big things is just to be a bit selfish, actually put ourselves first, think about what we're going to do.
Speaker BBecause if we are the more healthy version of ourselves, we can then look after other people.
Speaker BAnd that's really important.
Speaker AAbsolutely.
Speaker AAnd what does living an iconic midlife look like to you?
Speaker BOh, I wish I knew.
Speaker BIf I knew, I could tell you.
Speaker BI think being true to yourself and not comparing yourself with Others.
Speaker BIt's so easy as middle aged women to compare ourselves with others and think that we're not good enough, we haven't got this, we haven't done this.
Speaker BBut we've got to be comfortable in our own skin, otherwise we'll just, it can torment us.
Speaker AAnd what is one midlife rule that you are breaking?
Speaker BOh, people have called me a disruptor, but I used to be quite good at, you know, I was never a naughty person at school, but I don't like, there's no boundaries.
Speaker BI think what we can do now in, in this sort of modern world with social media, with media, I mean, look at us doing a podcast and we're not even in the same room.
Speaker BLike we couldn't have done that before, before.
Speaker BSo I think disrupting is, is something that I'm doing but with other women, I'm carrying women with me and everything that I do and that makes it really enjoyable.
Speaker AIt is, it's such a wonderful feeling to know that there's a community behind you.
Speaker AAnd what advice would you give your 25 year old self?
Speaker BOh, well, this is interesting because I've got three daughters, my oldest one's 22.
Speaker BI would just be more kick ass.
Speaker BI would be making sure, sure that I really knew as much as possible about my hormones.
Speaker BSo my oldest daughter takes hormones, she takes natural hormones and lots of her friends are taking synthetic contraception or they're feeling dreadful.
Speaker BAnd she said to them the other day, do you know what, guys?
Speaker BI feel the same every day of my cycle.
Speaker BLike, I don't even know where my cycle is because I feel great every day.
Speaker BAnd they were like, no, how, how does that happen?
Speaker BAnd they're like, let me like take Tell me the secret Jess.
Speaker BAnd she's like, well, just Google my mum and you'll find out about hormones.
Speaker BSo, you know, no one's too young to have this conversation.
Speaker BAnd I think even as a young person, if you're helping your parent, your auntie, your teacher, someone you work with, or for you as you become older, or looking around and helping your friends, you know, Jessica's helped a lot of friends who have been on antidepressants, all sorts, and now they're on hormones.
Speaker BSo being really, you know, inquisitive, because that's how this conversation about hormones is changing, because women are asking the right questions.
Speaker AAnd if somebody is starting natural hormones that young, does that substitute for contraception or is it just to keep hormones?
Speaker BThis is a whole other conversation because what's very interesting is that Hrt has never been tested as contraception.
Speaker BBut we have to remember when contraception was launched in the 60s, it was never tested as contraception.
Speaker BIt was only to help our periods.
Speaker BBut because the drug companies knew they'd make a lot of money, they changed the licensing without the evidence.
Speaker BSo, you know, but with a lot of people now, younger people will go for a coil, even a copper coil, for example, to use that as contraception.
Speaker BAnd then if they have PMS or PMDD like my daughter has, they might use natural hormones just to top up their own hormones.
Speaker BSo they're still having hormones, but they're just having a low dose to just top up and regulate their own hormones in a natural way.
Speaker BBecause if they're given synthetic hormones, they'll block their natural hormones and often make them feel worse.
Speaker BSo it's a different way of thinking about hormones.
Speaker AOh, that's fascinating.
Speaker AAnd I bet she feels so much better too.
Speaker BYes, she does.
Speaker BShe absolutely does.
Speaker BAnd she has really bad migraines, so that really helps with migraines as well.
Speaker AIf you have a moment, I would love to go through just a few myths, if you could say true or false about these, because as you know online, there are many, many stories flying around.
Speaker AOk.
Speaker AOkay.
Speaker ASo the first myth, Mythbuster.
Speaker ATrue or false.
Speaker AYou can't be in perimenopause if you're on birth control.
Speaker BBoth.
Speaker AOh, okay.
Speaker AYou don't need to treat vaginal atrophy if you're not having sex.
Speaker BThat is a big false.
Speaker AOkay.
Speaker AProgesterone is only needed if you have a uterus.
Speaker BThat's a false.
Speaker ANon menopausal women in their 30s should get a basic hormone blood panel to to get a baseline understanding of their hormone levels before perimenopause starts.
Speaker AOh, is that right?
Speaker AYou don't need the baseline.
Speaker BWhat is baseline?
Speaker BAnd it will change.
Speaker BIf you have eight blood tests in a day, you'll get eight different results.
Speaker BSo, wow.
Speaker BOkay.
Speaker AThat's how much our hormones fluctuate.
Speaker AOkay.
Speaker AOnce you're in menopause, your hormones stay low and steady.
Speaker BThey stay low, but not always steady because they can change because our muscles will produce some hormones.
Speaker BOur heart produces hormones.
Speaker BSo they will fluctuate, but they will generally be low.
Speaker AOh, wow.
Speaker AOkay.
Speaker AMenopause does not affect your eyes.
Speaker BNo, that's false.
Speaker BSo it does.
Speaker AI knew it.
Speaker AI knew it.
Speaker AMy vision is just going more and more each day.
Speaker AOkay.
Speaker ASo that is a direct result.
Speaker AThat's good to know.
Speaker AYou can't take HRT if you've Had a family member with breast cancer.
Speaker BOkay, so you can take it.
Speaker AYou can take it.
Speaker AOkay.
Speaker AYou only lose bone density after menopause.
Speaker BYou lose about 16 in perimenopause.
Speaker AOh, my gosh.
Speaker AJust.
Speaker AThe good news keeps coming.
Speaker AMenopause makes your feet grow.
Speaker BMake sure.
Speaker BWhat?
Speaker BFeet grow?
Speaker AFeet grow.
Speaker BNo, probably shrink a bit, actually, with bone loss and cartilage loss.
Speaker AAh, okay.
Speaker ANight sweats only happen at night.
Speaker BWell, if you call them night sweats, then they will.
Speaker BBut sweats can happen any time of the day.
Speaker AOkay.
Speaker AHormones don't affect your gums or teeth.
Speaker BNo, they do.
Speaker AThey do.
Speaker ASo there is.
Speaker AThere's gum loss.
Speaker BYeah.
Speaker AThe teeth become weaker, all the things.
Speaker AGreat.
Speaker AYou can't get pregnant during perimenopause.
Speaker AOkay.
Speaker ASo listen up, ladies.
Speaker ABe protected.
Speaker AMenopause starts at 50 for some women.
Speaker BBut a lot of women know it can be other ages.
Speaker AOkay.
Speaker AIf your periods are regular, you're not in perimenopause.
Speaker AOh, okay.
Speaker AYou only need estrogen for hot flashes.
Speaker ABoth bioidentical hormones are always natural and safe.
Speaker BSo they are natural.
Speaker BUsually you just have to be careful who makes them.
Speaker BReally.
Speaker BIt's like anything, the hormones bit's fine, but it's how they're made and they're.
Speaker AFormulation and they're formulated.
Speaker AWeight gain in midlife is all about eating more and exercising less.
Speaker ANo, False.
Speaker AMenopause means your sex life is over.
Speaker BNo, not at all.
Speaker AIt can actually get better.
Speaker BYeah, we should all be having if we want it.
Speaker BYou know, sex isn't a bad thing.
Speaker BYou know, look how easy it is to get Viagra.
Speaker BLike for men, it's very accepting.
Speaker BIt's something that.
Speaker BYeah, we, we feel embarrassed talking about sex.
Speaker AAnd we shouldn't, we shouldn't.
Speaker AIt's the age old double standard.
Speaker AMenopause only lasts a few years.
Speaker BIf you're going to die a few years after your menopause, yes, but otherwise, no.
Speaker AAnd testosterone is a male hormone and.
Speaker BA female hormone, so that's true, but it's not exclusively.
Speaker AAnd your body doesn't need hormones after menopause.
Speaker AIt's natural to age.
Speaker BNo, no, we have to.
Speaker BWe have to remember about natural and aging.
Speaker BYou know, there's lots of things that occur as we age, like raised blood pressure, but we don't watch someone's blood pressure get higher and higher.
Speaker AOh, my gosh.
Speaker AWell, Dr.
Speaker ANewson, this has been the most informative hour.
Speaker AThrilled to have had you on the iconic midlife.
Speaker ANo doubt our audience will just resonate so much with this episode.
Speaker ASo I thank you so much for your knowledge.
Speaker BOh, well, thanks for inviting me.
Speaker BIt's been a lot of fun.
Speaker BThank you.
Speaker AAbsolutely.
Speaker AAnd can you tell the audience where they can find you?
Speaker BYeah, the easiest thing is just go to my website.
Speaker BSo it's Dr.
Speaker BDrink louisenewson.co.uk, and then I've got all my resources and information there.
Speaker AThank you Dr.
Speaker ANewson, for sharing your wisdom, your knowledge and your amazing expertise with us today on the Iconic Midlife.
Speaker AAnd thank you to the audience for listening to the Iconic Midlife.
Speaker AIf today's episode made you laugh, think or feel a little more like a powerhouse because you are, follow the show on your favorite podcast app and leave us a five star review.
Speaker AWink, wink.
Speaker ANew episodes drop here every week and you can catch the full video version on YouTube tomorrow.
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