Welcome to the VP Life Podcast, the show where we bring you actionable
Speaker:health advice from leading minds.
Speaker:I'm your host, Rob.
Speaker:My guest today is Sally Norton.
Speaker:Sally is nutritional consultant and oxalate educator who's on a mission
Speaker:to educate the world at large on the potential dangers of oxalates.
Speaker:Expect to learn what oxalates are and what foods they're commonly found
Speaker:in, how oxalates can damage cells and drive disease, and the best strategies
Speaker:to detox from oxalates safely.
Speaker:Now onto the conversation with Sally Norton.
Speaker:Good morning Sally, and thank you for joining us today.
Speaker:I'm very familiar with your work and so I'm excited and honored to have
Speaker:this opportunity to chat with you.
Speaker:Uh, I know you've been fairly popular on the podcast circuit as of late,
Speaker:and while most in the holistic health space are likely familiar with you
Speaker:and your work, there will be those who maybe aren't as familiar with you, uh,
Speaker:especially in our audience over in the uk.
Speaker:Would you mind introducing yourself and running us through your story?
Speaker:Well, I have been a, a nutrition geek since kindergarten, since I
Speaker:was a little preschooler, long time interest in trying to be healthy.
Speaker:And in middle school when I was about 12, I had this insight in science
Speaker:classes like, oh, you mean you can avoid major chronic diseases potentially
Speaker:because nutrition has a major role in whether you get really sick and a
Speaker:major role in prevention of disease.
Speaker:And so I've been trying to do well since I was a little child,
Speaker:eat just the right things.
Speaker:And unfortunately I did everything right but struggled with health
Speaker:problems from early on in life.
Speaker:And it became disabling in college, in graduate school and again and again,
Speaker:over and over again, I'm running into major problems that are interrupting
Speaker:my career and I was at a loss for answers and I'm in my late forties.
Speaker:I'm an expert in holistic and I healthy living and and therapies
Speaker:and integrative medicine and.
Speaker:Public health and nutrition, successful aging.
Speaker:And I didn't know what was wrong with me and neither did my colleagues in
Speaker:functional medicine and holistic healing and standard medicine nobody was giving,
Speaker:pointing me to the answer until one symptom in 2009 pointed me to an outfit
Speaker:online called the Vulva Pain Foundation.
Speaker:Vulva Pain is a gen genital pain burning that ruins your life, and it took me
Speaker:another nearly four years to really have this breakthrough insight that brought
Speaker:me into this mind bending realization that led me to more and more surprises
Speaker:as I started to get better by taking out my lifetime of spinach bee greens.
Speaker:It was really Swiss chard, sweet potatoes, and holy cow, all kinds of old
Speaker:problems started unwinding themselves.
Speaker:So I talk about this.
Speaker:In my book, toxic Superfoods, and on my website on the about page, there's a
Speaker:little summary of, wow, it took, I had to really get over all the knowingness of all
Speaker:my knowledge and be desperate enough to recognize that the enemy was right on my
Speaker:plate and my organic garden in my kitchen.
Speaker:Wow.
Speaker:Yeah.
Speaker:Yeah.
Speaker:Talk about being fed a lie.
Speaker:I think, uh, I came up with that on this, sorry.
Speaker:That's my best joke for the day.
Speaker:Unfortunately, we're feeding lies to pregnant women and babies too.
Speaker:I mean, this is, we can kind of laugh at our own suffering and go, oh,
Speaker:well, at least she made it to her sixties and got through that somehow.
Speaker:But if only we had known this earlier in my life, and only if
Speaker:we can now help others because.
Speaker:We're in an age now with the foods that we're supplying this damage to
Speaker:my life are universally revered and trusted and assumed to be innocent.
Speaker:Yeah.
Speaker:And, and I think that's definitely, uh, a point we'll
Speaker:get onto later on in the podcast.
Speaker:Thank you for that.
Speaker:Your star.
Speaker:I reckon we should, we might as well get into the, the meat and
Speaker:potatoes or I suppose the spinach might be applicable of, of today's
Speaker:conversation, um, which is oxalates.
Speaker:And, uh, um, we've obviously, you've already already alluded to them, uh, but
Speaker:at a high level, could you explain to the audience what exactly oxalates are?
Speaker:Um, I know you've mentioned some food sources already, but what are these,
Speaker:uh, these plant chemicals that seem to pose such an issue for so many people?
Speaker:Right.
Speaker:So plants make this oxalic acid.
Speaker:Oxalic acid is a small little molecule.
Speaker:It's a chelating acid.
Speaker:Two little carbons with four oxygen, which is really interesting.
Speaker:And it's so heavily oxygenated.
Speaker:It's really di carbolic acid.
Speaker:So this thing likes to grab positively charged ions like calcium, magnesium.
Speaker:All the minerals out there tend to get bound up with oxalic acid.
Speaker:And then we call that an oxalate when it's in connection with a metal.
Speaker:And these oxalates form bonds with each other.
Speaker:Little pairs of them, groups of pairs.
Speaker:About eight or 12 pairs come together and they form nano crystals.
Speaker:This is crystallization and start to build into crystals.
Speaker:Those crystals are commonly seen in kidney stones.
Speaker:So oxalic acid, that's plants make soils, make it from the, the
Speaker:fungus and so on in the soils.
Speaker:It even is made.
Speaker:It's so easy to make it in nature.
Speaker:Clouds with a little bit of pollution and moisture will form oxalic acid.
Speaker:We've had a problem here in the Eastern United States.
Speaker:Uh.
Speaker:Acid rain.
Speaker:It turns out oxalic acid is the major acid in acid rain, and it melts monuments and
Speaker:causes problems with soil pH and so on.
Speaker:So it's everywhere.
Speaker:It's ubiquitous in nature.
Speaker:A lot of plants make it so much of it that they're completely inedible.
Speaker:And then there's the ones we've bred for the produce aisle, which have less.
Speaker:But some of those we cannot seem to breed well enough to get them
Speaker:low enough to really be safe.
Speaker:And somehow we're ignoring it.
Speaker:So yeah, oxalic acid, oxalates, it's set in the plural.
Speaker:It forms these different forms from an acid to a molecule to a crystal.
Speaker:Different kinds of minerals can be connecting to it, and it can
Speaker:change places and move around.
Speaker:So we call 'em oxalates, plural.
Speaker:We're talking kind of generally about crystals and an acid, a free acid,
Speaker:and they have different properties and different tendencies in the bodies.
Speaker:So it's important to kind of know there's this soluble acid.
Speaker:And then there's these insoluble calcium oxalate crystals, which
Speaker:become a crystallization in the body.
Speaker:Yeah.
Speaker:And are, are the, are oxalates, uh, I suppose produced at all in
Speaker:the human body in endogenously.
Speaker:Do do you humans produce these, these molecules or do they just come from diet?
Speaker:Well, they, you can eat it directly in the foods that are all plant
Speaker:foods, animal foods don't have it.
Speaker:And then there's the, the transformation of precursor molecules into oxalic acid.
Speaker:And that does occur in the body to a small degree.
Speaker:We produce about an average of 12 milligrams daily in this
Speaker:sort of endogenous process.
Speaker:But the very interesting thing about it, if you understand what these
Speaker:precursor molecules are that become oxalate, you realize the big one that's
Speaker:producing more than half, probably at least 40%, maybe much more than
Speaker:that, of this endogenous production.
Speaker:This little 12 milligrams is coming from vitamin C supplementation.
Speaker:Oh yeah, no, and I think there are a bunch of other, uh, offending
Speaker:supplements out there, such as glycine that can also contribute as well.
Speaker:As far as know, glycine is
Speaker:not so bad.
Speaker:It's a pretty small amount.
Speaker:It's a hydroxyproline is worse, which is in collagen.
Speaker:So if you're using whole collagen and you're using more than maybe four
Speaker:teaspoons a day, which is, what is that?
Speaker:Um,
Speaker:20 grams or so?
Speaker:20 mils, yeah.
Speaker:So that's enough to start generating more oxalate in the body, but it's
Speaker:still a relatively small amount.
Speaker:But you can, people literally can feel the difference when they quit overdoing
Speaker:the collagen supplements or they stop the vitamin C. Those two things can be
Speaker:major ways of protecting yourself from this so-called endogenous production.
Speaker:But to me, if it's coming from something you're eating and have
Speaker:an option to not eat, I. That's not really endogenous production so much
Speaker:just because the transformation's occurring inside the body.
Speaker:So it's kind of a misnomer that's been abused by people who wanna just be, have
Speaker:carte blanche to eat what they want.
Speaker:Ah, your body's making it anyway, so what?
Speaker:Well, with toxins, your body does make toxins.
Speaker:That's why you pee it out.
Speaker:That's why you make feces.
Speaker:That's why you peel off your skin and you sweat and you have, you have lymph
Speaker:glands and all this stuff because you're moving toxins outta the body.
Speaker:Even the fluids from the eyes, you are moving toxins outta the body.
Speaker:Of course, the body both receives and creates tox, toxins, but it
Speaker:doesn't mean that gives you permission to start picking out on toxins.
Speaker:Yeah, of course.
Speaker:Yeah.
Speaker:I suppose that sort of does, that sort of almost begs the question, is there any.
Speaker:Reliable data on why we have oxalate in the body.
Speaker:Uh, is that something you know of hand Maybe.
Speaker:Is there a sort of a place, is there a biological requirement for oxalate at any
Speaker:level or is it something that we ju is it purely something that is introduced
Speaker:to our diet that shouldn't be there, that causes more problems than it's worth?
Speaker:Right.
Speaker:So this is a, a potentially complex conversation because we see, we see
Speaker:sort of free radical production by mitochondria as signaling molecules that
Speaker:helps the body make more glutathione and start fighting back and do good things.
Speaker:So there sometimes something that's too much of it is bad, a little bit is
Speaker:good, and the right environment is good.
Speaker:So is a little bit of oxalate good or not?
Speaker:It, it's never shown up as being a signaling molecule that's creating
Speaker:some kind of defense response.
Speaker:And the only possible advantage that I've seen is that the oxalate
Speaker:that's concentrated in the saliva.
Speaker:Might actually form a tartar on the teeth that's somewhat protective.
Speaker:Okay, good.
Speaker:But in the, in the mitochondria, in the cells, they would do fine
Speaker:without something that's ruining the membranes and interfering with enzyme
Speaker:production or enzyme function and causing all kinds of, um, oxidative
Speaker:stress using glutathione against.
Speaker:There haven't, there isn't really, um, there are people who wish
Speaker:there was, and they're not the real scientists who are saying, well,
Speaker:we don't see it.
Speaker:You've already answered this in a sense, but I'd love to clear, get a,
Speaker:excuse me, a clearer picture here.
Speaker:Um, as I've alluded to earlier, I've listened to several of your
Speaker:conversations you've had recently, especially with individuals, um, with
Speaker:let's say more restrictive ideas and ideologies when it comes to diets.
Speaker:So your Anthony Chaffee of the world who are obviously fairly firm
Speaker:believers, uh, in the idea that plants.
Speaker:All of them are, are trying to kill us.
Speaker:Um, now I do think a carnival diet is definitely a useful tool, um, for certain
Speaker:people at certain times of in their lives and, and that it can be very effective
Speaker:as an elimination diet and all of that.
Speaker:Um, I suppose this is a bit of a broader question, but where
Speaker:do you stand on the spectrum?
Speaker:Do you feel, uh, that we should be getting rid of most plant
Speaker:matter for the whole part?
Speaker:Um, or do do plants have a, a place in the human diet?
Speaker:Uh, I suppose what I'm asking is are vegetables trying to kill us?
Speaker:Well, you know, we don't necessarily wanna do a prescription for all of humanity yet,
Speaker:but if we're thinking just generally in principles about what is humanity meant
Speaker:to be eating and what's really optimizes health versus what you can get away with,
Speaker:I mean, there's all kinds of angles you could take to these questions if you're
Speaker:interested in optimization and protecting.
Speaker:The health of the future generations.
Speaker:And you're really interested in seeing functional longevity, not just hospital
Speaker:based longevity and drug supported fake longevity, but actual vital
Speaker:functioning, healthy, full life, living up to the some nice rip mature age.
Speaker:There's a lot of questions there about whether plants at all necessary.
Speaker:Can you live that optimal life and can you produce healthy generations
Speaker:going forward without plants?
Speaker:And there's evidence that you can, there's, there's peoples on this
Speaker:earth who've lived in areas that don't have any plants like the ice poles.
Speaker:The northern, the northern regions of Alaska and that kind of place do have done
Speaker:pretty well without much plants at all.
Speaker:And, uh, certain tribals, people like the Messiah traditionally in the
Speaker:old days would have very few plants.
Speaker:So we know that human beings.
Speaker:Don't necessarily have to have plants to be healthy.
Speaker:And that in itself is a huge controversial idea because we've
Speaker:been told in modern life that plants have essential planty stuff.
Speaker:These phytonutrients, you gotta have 'em, they're gonna give you
Speaker:longevity and all this stuff.
Speaker:But that is based, that is standing on a pillar of jello.
Speaker:'cause we came up with this idea that there were these antioxidants in plants
Speaker:as a back of the envelope placeholder.
Speaker:That hasn't held up at all.
Speaker:They have not been able to demonstrate any kind of consistent way where, say
Speaker:polyphenols or whatever, consistently in all people have this beneficial effect.
Speaker:And if and when it has a beneficial effect, it's because it's interacting
Speaker:luckily with certain genetics and certain microbiome in the colon.
Speaker:And if you don't have those genetics in that microbiome and you don't know
Speaker:which ones to use, there's tens of thousands of polyphenols and so on.
Speaker:We, we have no way to actually use that concept effectively for all people.
Speaker:Um, and what's happening is that we have this selective idea
Speaker:of this benefits only mindset.
Speaker:So there might be something great in plants, maybe sometimes,
Speaker:probably, okay, but which ones?
Speaker:How much?
Speaker:And so on.
Speaker:We've got this blind spot around.
Speaker:Well, what about the antinutrients implants?
Speaker:Toxic chemicals, generally, their effect on illness and aging has
Speaker:been overlooked for a long time.
Speaker:In general, by everyone excluding science and with oxalate.
Speaker:Science is very familiar with the toxicity of oxalate and yet clueless about the
Speaker:impact of oxalate in our foods, on our health in the short, in the long
Speaker:run on reproductive health and so on.
Speaker:And modern research is so over focused on kidney stones and they have an agenda
Speaker:that would have them pretend We don't know that diet is supplying the required
Speaker:material to become kidney stones.
Speaker:If you say that, then why do you need funding forevermore?
Speaker:Why do you need to captivate all funding and oxalates for 70 years
Speaker:when you're busy pretending it's not made of the stuff you're eating?
Speaker:And we know that the diet is the main cause of that.
Speaker:So there's a lot of things around us that are affecting our viewpoint about diet.
Speaker:Personally, I do think plants have a right to take care of themselves in a,
Speaker:you know, we ourselves, we need to be less disneyfied in our thinking, like
Speaker:we have to be a little more logical.
Speaker:You have to think the science is not a Disney movie or Nature's not
Speaker:a Disney movie, but nature is claws, lightning, fire, death, destruction,
Speaker:hurricanes, you know, such a nice place.
Speaker:Nature's a rough place.
Speaker:Yeah.
Speaker:So Oxalate is a tool harnessed by plants brilliantly for their
Speaker:own survival and self-defense.
Speaker:They cannot afford to play nicey nicey like they do in Disney movies.
Speaker:They have to take care of business and survive.
Speaker:If they were completely non-toxic, they'd be extinct.
Speaker:Yeah.
Speaker:And what do you think about fruits in that regard?
Speaker:Uh, I mean, fruits, uh, have a, uh, a different sort of biological imperative.
Speaker:I mean, they, they contain seeds.
Speaker:They, uh, the idea being, they're obviously that they sort of, the aim is
Speaker:for them to be ingested so that those seeds can then be, uh, dispersed across
Speaker:the landscape and, and that plant can, well, in this case, that fruit can then
Speaker:seed and, and produce more offspring.
Speaker:Um, do you think fruits carry the same level of, of, of issues
Speaker:potentially That is, well, you can
Speaker:say the same for nuts too, because nuts are, um, squirrels and other vermin
Speaker:are very busy, interested in nuts and burying them for the trees and so on.
Speaker:And so trees and plants are using the mobile animal kingdom to support
Speaker:that seed distribution as they use wind and water and other natural
Speaker:tools to dis disperse their seeds.
Speaker:There are plenty of berries on plants that you would never let a child eat because
Speaker:only a bird can survive eating them.
Speaker:So fruits aren't necessarily needing us to survive to have that dis
Speaker:dispersion 'cause there's other creatures helping them disperse.
Speaker:So it's a mixed bag.
Speaker:But for the fruits in the produce aisle that we've bred and bred and bred to
Speaker:make sweeter and more interesting and more full of calories and enjoyment, most
Speaker:of them are okay in terms of oxalate.
Speaker:And the main exceptions are blackberries, kiwis, figs, pomegranate
Speaker:plantain, raspberries is as well.
Speaker:And star fruit is absolutely poisonous.
Speaker:So, but most of the other fruits are fine and the, the fruit.
Speaker:So here's a, a chance to get into the.
Speaker:Geeky nitty gritty distinction and oxalates.
Speaker:Yes, please.
Speaker:So there's soluble oxalic acid and then there's calcium oxalate crystals.
Speaker:And the fruit seems to have the insoluble oxalates.
Speaker:So they're probably very small crystals attached to membranes and fibrous
Speaker:materials, and they're not, probably not as absorbed into the bloodstreams.
Speaker:So the acid moves between cells of the gut and gets into your bloodstream pretty
Speaker:easily and fairly quickly, right up in the stomach and upper small intestine.
Speaker:Whereas this insoluble stuff would take a long time, maybe all
Speaker:the way to the colon before it's available for absorption, if at all.
Speaker:So you don't get as much of it messing with your blood system, your blood
Speaker:cells, your vascular system, and your organs just messing with your gut.
Speaker:So the fruit is more likely to deliver these crystals that are pretty hard
Speaker:hardcore, like the Kiwi has the.
Speaker:The toothpicks shaped crystals, the RAF hides, and these are bundles of
Speaker:hundreds of these little toothpicks with points on both ends that are
Speaker:designed to penetrate the mucosal cells.
Speaker:Two cells deep, but technically the cell lining of your intestinal
Speaker:tract is only one cell deep.
Speaker:So you're eating ground glass when you're eating kiwi and things like
Speaker:this, and that's causing oxidative stress or, or you know, mechanical
Speaker:abrasion, which is a type of toxicity.
Speaker:So it's a different kind of toxicity.
Speaker:So fruits in moderation, no problem, probably.
Speaker:Um, and yeah, I think we need carbs.
Speaker:I think we're drawn to carbs.
Speaker:We have sugar tasting tongue.
Speaker:We're attracted to it.
Speaker:We're designed to eat carbs because that's what the tongue is telling us.
Speaker:You want this sweet stuff, but in nature it just was hard to get carbs because
Speaker:those fruits, uh, in nature aren't as sweet as the ones in the produce aisle.
Speaker:They're not as big and juicy.
Speaker:They're small and bitter and tough and have skin and seeds and.
Speaker:So, yeah, I, you know, if you, depending on what really is the question is, the
Speaker:question is historically ancestrally, were fruits important part of the diet,
Speaker:probably just very seasonal, a little bit of drying of berries and things like that.
Speaker:Not as big a roll as we might like with like bananas and apples
Speaker:everywhere you turn, and bright oranges everywhere that we have now.
Speaker:But I think fruits are, um, a nice way to have flavor and color and vegetables
Speaker:the same way vegetables bring you texture and diversity and color and
Speaker:interest and culinary possibilities.
Speaker:And you can expand that kind of, sort of hedonistic desire to have
Speaker:interesting food, um, has its value.
Speaker:You build culture on that, but it's not necessarily critical to human health.
Speaker:Yeah, I suppose I, I've still yet to sort of come to a conclusion on, on,
Speaker:on the, on the plant side of things.
Speaker:Um, definitely not a microbiologist, I'm a chemist, so I look at it more
Speaker:from a sort of a perspective of fats, uh, carbs and proteins and all of that.
Speaker:And you raise an interesting point where you said you need, uh, well,
Speaker:where, when you said that we need carbohydrates as a species, and I
Speaker:think I, I, I would agree with that.
Speaker:For the most part, I think a lot of people can get away with the ketogenic diet.
Speaker:Um, however, I think for a lot of people being in that sort of long
Speaker:term state, ketosis can potentially have downsides, especially for, for
Speaker:younger women who, who are of, uh.
Speaker:Yeah.
Speaker:Who are, who are of fertile age.
Speaker:Um, I think when you start restricting carbohydrates, you can start
Speaker:increasing, uh, SHBG and th uh, thyroid binding globulin and, and drive and
Speaker:cause all sorts of, uh, endocrine dysfunction, um, as a result of this.
Speaker:Mm-hmm.
Speaker:Over restriction of carbohydrates.
Speaker:So I think for certain groups of people it is def it's definitely required.
Speaker:Um,
Speaker:and you can play with the tool of ketosis Yeah.
Speaker:And go in and out of ketosis.
Speaker:Oh, definitely.
Speaker:And have that metabolic flexibility without having to stay in some
Speaker:deeply the therapeutic, I mean, any therapy that needs to happen every
Speaker:day of your life forevermore doesn't make sense as a therapy anymore.
Speaker:And we lose sight of that.
Speaker:You can have benefits from a certain technique or herb or anything else,
Speaker:but usually the short term value is really where it's at when you
Speaker:start doing something chronically.
Speaker:It has a different effect and sometimes that effect is harmful.
Speaker:Yeah, no, I, I couldn't agree more.
Speaker:Um.
Speaker:You've already touched on it, um, to some extent, but I'd love to sort of go into
Speaker:a little bit more detail with regards to how oxalates are potentially damaging
Speaker:the mitochondria or our mitochondria, the powerhouses of our, of our bodies,
Speaker:and how they are sort of creating this sort of, this, this disruption at a
Speaker:cellular level, um, and creating, uh, an energy deficit within the body.
Speaker:Because I think, uh, based again on my research and my background, ultimately
Speaker:all disease or disease, uh, ends up with these, these organ, these all organelles
Speaker:in the cells becoming ineffective at doing their job, which is to create energy.
Speaker:And obviously there, there are a lot of potential causes, uh, for that.
Speaker:They, they're normally toxin in nature, whether that's mold or another infection.
Speaker:Obviously today, um, we're talking specifically about oxalates and to a
Speaker:larger, to a big extent, I suppose, plant def uh, defense, uh, chemicals, but.
Speaker:Would you mind elaborating again at a relatively high level, obviously, so
Speaker:it's accessible, um, how oxalates are essentially creating this mitochondrial
Speaker:dysfunction and this subsequently this lack of available energy.
Speaker:This is sort of almost a idea of, hello, life is energy.
Speaker:You're not alive without energy, and anything that cuts your energy
Speaker:is cutting back on your life.
Speaker:And this profoundly important to think about energy, energy production,
Speaker:energy availability for your cells.
Speaker:And of course, the mitochondria are the major factories that's managing energy
Speaker:sources and turning them into energy currency that allows your cells to
Speaker:function properly and do all their jobs.
Speaker:And when that currency runs short.
Speaker:The cell's ability to do its job are highly compromised, and then
Speaker:you're on your way to disease.
Speaker:You absolutely need cells that have enough mitochondria that are
Speaker:working well in order to grow, thrive, and maintain your tissues.
Speaker:When your tissues don't make enough energy, they start falling apart.
Speaker:And oxalate is a major energy suck from the body and it's you're eating it and
Speaker:you can't eliminate it through metabolism.
Speaker:You can't metabolize it.
Speaker:You just move it around the body and try to get rid of it.
Speaker:But in the meantime, every tissue is exposed to, or that is exposed to, it
Speaker:is potentially damaging cell membranes, especially if there's a crystal formation
Speaker:going on because there's a charge there.
Speaker:Cell membranes have this double lipid structure and this bilipid layer has
Speaker:a very particular structure where certain molecules are on the inside
Speaker:and certain ones are on the outside.
Speaker:Well, it causes a, a flip where one of the molecules is supposed to be on
Speaker:the inside, only flips to the outside.
Speaker:And this is really quite serious because membranes are where energy is produced.
Speaker:Inside membranes sit, these big proteins, these enzymes in these series of enzymes
Speaker:that are happening on all the membranes.
Speaker:If this, the fatty molecules that make up the membrane are wrong, then
Speaker:the, the proteins themselves that do this work don't work right either.
Speaker:So now you've got a damaged cell membrane, which is the sort of factory
Speaker:walls and floors that allows your factory to do this energy handling.
Speaker:And so you've got membrane changes, you've got oxidation
Speaker:going on, and that's depleting the antioxidant capacity of the cells.
Speaker:So you start using up glutathione and then you're.
Speaker:Own capacity to handle that.
Speaker:Stress goes way down.
Speaker:And so things go from broken to more broken to more broken, and you
Speaker:start damaging proteins, oxidizing the lipids, all these other
Speaker:molecules start to be messed up.
Speaker:The immune system recognizes, starts taking the cells away, but
Speaker:particularly in the mitochondria.
Speaker:So there should have plenty of mitochondria, especially in cells like
Speaker:muscle cells, nerve cells and so on.
Speaker:You're penetrating the mitochondria with this little oxalic acid molecule and
Speaker:messing with the handling of calcium.
Speaker:So the cells have to have very tight control over these ions of calcium.
Speaker:That's an individual molecule with charge, usually two charges on a calcium ion.
Speaker:And this little.
Speaker:This little molecule is a signaling molecule that helps the
Speaker:cell decide what to do when and what it's supposed to be doing.
Speaker:It's very interesting.
Speaker:You have to control that with these sub organelles like the mitochondria
Speaker:and another one called the endoplasmic reticulum and control what's going
Speaker:on between those two organelles with where calcium's moving back and forth.
Speaker:While here you have a calcium chelator that grabs the calcium and causes calcium
Speaker:buildup where it shouldn't be, and calcium depletion and just interferes with the
Speaker:entire communication system in a cell.
Speaker:Um, and then you've got the, the oxalic acid will sit on these enzymes needed to
Speaker:produce energy and to produce glucose.
Speaker:So there's four or five of these.
Speaker:These enzymes that where there's a spot there where the active site, where
Speaker:oxalate fits in there just perfectly.
Speaker:So these pyruvate, um, carboxylase and so on that generate in the first run,
Speaker:when you take glucose and try to turn it into the currency of a TP, you've got
Speaker:this last step that helps produce these ATVs that gets blocked by an oxalate.
Speaker:And then in your electron transport chain down in the mitochondria, you've
Speaker:got complex two and so on and so on.
Speaker:Being interfered with, so you're breaking the machinery itself.
Speaker:So we have this factory, the cell, the floors, the walls are messed
Speaker:up and now you're, the actual equipment is broken through oxalate
Speaker:interfering with enzyme function.
Speaker:So it's kind of a mess.
Speaker:Yeah, so if I was to summarize that for the audience, at a high level,
Speaker:what's happening is that to start off with oxalates getting to the body, uh,
Speaker:then it's essentially, it's damaging the, the cell membrane layer, which is
Speaker:causing almost well the cell to act at a dysfunctional level, but it's also gonna
Speaker:cause, um, altered cellular communication.
Speaker:Um, you're also going to then have, uh, oxalate sort of get into the cell and
Speaker:start interfering with, uh, the cell's ability to utilize calcium properly.
Speaker:Uh, I assume that's through some sort of voltage gated cha uh, calcium
Speaker:channels, something to that extent.
Speaker:Um, and that is then causing either the influx of, of calcium
Speaker:into the cell and damaging a cell.
Speaker:'cause obviously, uh, as you know, if there's too much calcium in
Speaker:the cell, it, it causes, it can call cell death, cell apoptosis.
Speaker:Um.
Speaker:And then beyond that, it's also, uh, at an enzymatic level, it's, it's, it's,
Speaker:uh, causing calcium to, uh, if I follow correctly, to bind to, uh, specific places
Speaker:in the cell that, uh, cause this cause the cell then to not produce energy properly.
Speaker:Uh, would that be a relatively, sort of a decent summary or have
Speaker:I, did I miss anything at all?
Speaker:Yeah, well, one of the things I didn't mention is that when you
Speaker:get this oxidative damage and or low a TV production, you have.
Speaker:Changes in the expression, the methylization and the aging of the
Speaker:cell and the protein management.
Speaker:You know, you're supposed to clear unfolded proteins and do all that stuff.
Speaker:All that kind of cell aging gets out of control and you get epigenetic changes
Speaker:and the cell starts acting differently.
Speaker:So sometimes it turns cells like a normal epithelial cell into a bone
Speaker:producing cell and starts causing calcifications of other kinds because
Speaker:you've messed up the genetic expression.
Speaker:So the cell gets confused about what kind of cell it is, goes through
Speaker:these, and it turns on cytokines that just promote that process.
Speaker:So the cytokines come along to deal with the crystals that are forming
Speaker:in those tissues along with these, this basic oxalic acid interfering
Speaker:with the mechanism of the factory.
Speaker:But you've also got this crystallization bringing in
Speaker:additional inflammation because inflammation comes in when the cell.
Speaker:The system detects this leakage of potassium and other problems with the
Speaker:cell, with the membrane structures.
Speaker:It comes along to try to get rid of the broken cell.
Speaker:And that broken tissue creates a room for, um, crystallization because
Speaker:the cul debris stimulates more precipitation of acid into crystals.
Speaker:And then you get crystal adhesions, and now you have more cytokines
Speaker:coming in trying to fize and get rid of these crystal accumulations.
Speaker:And that additional work by the cells turns on the kind of damage that causes
Speaker:cells to go from normal good cells to problematic bone cells and other
Speaker:cancer cells and things like that.
Speaker:Yeah, no, it, it.
Speaker:Yeah, it, it basic.
Speaker:Basically what you're doing is you are just creating cellular dysfunction
Speaker:at such a high level that these poly or mitochondria are almost
Speaker:completely unable to produce energy.
Speaker:Um, I'd, I'd, I'd like to sort of go, uh, take a bit of a, a stab at, uh, to,
Speaker:um, conditions that I think and are.
Speaker:And I think Oxidate based on my sort of, and uh, uh, reading of the literature,
Speaker:and this is obviously not my field, there definitely could be a very
Speaker:strong oxalate, uh, aspect to this.
Speaker:Uh, number one being hypothyroidism.
Speaker:Mm-hmm.
Speaker:And number two, being broadly speaking, cognitive decline.
Speaker:Mm-hmm.
Speaker:Your, uh, dementia dementias, your Alzheimer's, et cetera.
Speaker:Mm-hmm.
Speaker:Um, I know I've heard you talk about, uh, this before e especially
Speaker:with regards to hypothyroidism, but could you maybe briefly
Speaker:explain the link between, um, yeah.
Speaker:Sort of oxalate overload and then, uh, these, uh, these, these conditions?
Speaker:Yes.
Speaker:The oxalate overload is, so we have diets overload with oxalate, and
Speaker:we're eating enough of this acid.
Speaker:It's getting into your bloodstream to a level that is not only
Speaker:damaging the vascular system and the cells in there, but it's really.
Speaker:Stressing the excretion capacity of the kidneys and the kidneys are
Speaker:the last tissue to see oxalate.
Speaker:Yeah, because it's coming first in your gut, then getting into your vascular
Speaker:system, which goes straight to your liver.
Speaker:So now the liver has this open sinusoidal structures because the liver
Speaker:is, is filtering everything coming through and transforming nutrients
Speaker:and catching any problematic things.
Speaker:And it's being, all these cells and liver are wide open, exposed to the
Speaker:oxalic acid that was in your spin it smoothie and your, and your, you know,
Speaker:quinoa bread and your almond, whatever.
Speaker:I mean your chia bowl.
Speaker:Whoa.
Speaker:After each meal, even just, um, hash browns and chips and fries kind of stuff.
Speaker:You're loading up that liver, using up glutathione, and potentially
Speaker:leaving enough oxalate behind where you get some accumulation.
Speaker:But most of it's gonna leave the liver.
Speaker:And you know what else happens in the liver is that's where this
Speaker:endogenous production is occurring.
Speaker:So the liver is adding more oxalate to that blood.
Speaker:So the blood that leaves the liver could even have more oxalate than it
Speaker:had when it started from your geo bowl.
Speaker:And it goes just a few inches up to your heart.
Speaker:So now that blood is flowing through your heart and then it goes into your
Speaker:lungs and it flows through your lungs, and then it flows back into the heart
Speaker:and down into peripheral circulation.
Speaker:Well, it's gets everywhere and it gets into glands like the thyroid
Speaker:gland, the pancreas, the pituitary.
Speaker:You know, glands seem to pick up oxalate connected tissue, picks it up.
Speaker:Tissues that have a lot of, uh, calcium handling, like the bones and the breasts.
Speaker:The breasts make milk.
Speaker:So those cells have a special affinity for handling and concentrating calcium.
Speaker:And so it accumulates in the thyroid gland almost universally.
Speaker:By the time you're middle age, you have an 85% chance of having
Speaker:detectable visible levels of crystals.
Speaker:Like it can be so small, it's almost undetectable, but it's there.
Speaker:So it is, but a detectable that's really quite something.
Speaker:And it's also collecting in other tissues as well.
Speaker:Your eyes, your brain, the meninges around your brain, that's the
Speaker:sheaths, the your teeth, your jaws, your sinuses, your bone marrow.
Speaker:And so this stuff is damaging the function of these tissues.
Speaker:And in the thyroid thyroid's not a huge thing.
Speaker:Very busy, important master gland.
Speaker:You could be interfering, like we just said, the energy production makes
Speaker:it harder to produce enough thyroxin or you know, various hormones that
Speaker:it's producing and you are seeming to collect it there and that the crystal
Speaker:accumulation increases inflammation.
Speaker:So you have sort of a Hashimoto's like kind of pattern 'cause you're
Speaker:bringing in inflammation to deal with this oxalate collection.
Speaker:So there's no question that oxalate is a major player in this.
Speaker:Now epidemic of thyroid problem, thyroid illness, and neurological damage.
Speaker:It's very much a neurotoxin, it collects in the brain as well.
Speaker:Yeah.
Speaker:I suppose that sort of really could, uh, explain some of the etymology behind a
Speaker:disease like multiple sclerosis as well.
Speaker:I think we just, you you touched on, uh, nerve degen, myelin degeneration, e
Speaker:uh, earlier this, uh, idea that within multiple sclerosis anyway, that it's a
Speaker:disease whereby the myelin sheathing, uh, sheath, the fatty sheath thing
Speaker:that surrounds nerves, starts to break down, exposing those nerves to, to
Speaker:oxygen, to blood, which then causes, uh, such of die off within, within brain
Speaker:cells, within nervous system tissue.
Speaker:Um, so yeah, I, I, I, I, that's a great
Speaker:example of tissue maintenance problems.
Speaker:The cells that keep and maintain that insulation and people may not realize,
Speaker:you know, if you think of a, a cord that you use to plug something in.
Speaker:Underneath this vinyl is the, the charge where all the
Speaker:electrons are running through.
Speaker:So nerves kind of need this vinyl around them to function properly,
Speaker:and that's that myelin sheath.
Speaker:And when it goes away, woo, you don't want that kind of
Speaker:exposure to this, um, electricity generation process and vice versa.
Speaker:So the tissue maintenance occurs on nerves as well as connective tissues
Speaker:and other tissues as well, where you've got an energy deficit and you
Speaker:have a toxicity, and then you have inflammation coming into those tissues.
Speaker:So those cells that are, whose jobs are to maintain that tissue, can't do
Speaker:their job because they're so damaged.
Speaker:Yeah.
Speaker:You just, you just completely create this sort of dysregulation, this sort of excess
Speaker:sort of allosteric load within the body that just causes this complete shutdown
Speaker:of all these systems and, uh, yeah.
Speaker:No, it's, well, even
Speaker:incomplete shutdown is enough.
Speaker:It doesn't even have to be complete.
Speaker:In fact, a lot of this is happening under the hood where
Speaker:you feel fine until you don't.
Speaker:Like there's a breaking point, like it can be going on.
Speaker:Disease is often asymptomatic, meaning you have to have some way to measure
Speaker:the disease process, you know, a blood pressure cuff or something to be
Speaker:able to even detect what's going on.
Speaker:And so the body tries real hard to look good, even if under
Speaker:the hood things are rough.
Speaker:And so that's, it doesn't need to be complete breakdown.
Speaker:And I think it's important to pause on this because in the literature
Speaker:we often look at the fatal dose.
Speaker:Well, it takes five grams to die from it.
Speaker:So it's okay, well wait a minute.
Speaker:What if I just feel like I'm dying?
Speaker:Isn't that bad enough?
Speaker:Do I have to actually die to prove that I'm poisoned?
Speaker:Yeah.
Speaker:No, I don't think so.
Speaker:Yeah, no, thank you for, uh, for catching that.
Speaker:No, it, it's definitely, uh, an important point to remember, uh, which really
Speaker:sort of is, is quite a nice segue to my next question, um, really, which is
Speaker:about how to identify whether or not it's necessarily an oxalate tissue.
Speaker:Um, uh, I mean.
Speaker:Yeah, if you don't mind, I'll, I'm just gonna throw my, uh, six pence
Speaker:worth into the, into the conversation.
Speaker:Great.
Speaker:And, and I understand that oxalates are an issue, es especially if there's
Speaker:a ge, a genetic predisposition.
Speaker:However, uh, I'm also aware that there are a bunch of other potential
Speaker:triggers, uh, some of which are, are plants, defense chemicals, so your
Speaker:FODMAPs, your lectins, your tannins, uh, and then you obviously have, uh,
Speaker:o other issues, um, just, uh, your, your proteins and your simple sugars.
Speaker:Uh, your, uh, lic
Speaker:acid.
Speaker:Yeah.
Speaker:Cain, lactose, your, all of that.
Speaker:So, I suppose my question is there, especially from a, a plant defense
Speaker:mechanism standpoint, which I, I suppose is, is apt because that's
Speaker:the conversation we're having today.
Speaker:How can you be sure that it is a, an oxidative issue?
Speaker:I, I suppose at the end of the day, versus.
Speaker:A screaming case of you've just eaten too much cabbage and your
Speaker:fob maps are through the roof.
Speaker:Right, right.
Speaker:So again, there's lots of different angles on this and different
Speaker:stages of when this is relevant.
Speaker:I, I would say on the, the side of, am I getting sick with something
Speaker:and what's making me sick on the, on this kind of progression towards
Speaker:illness, what was causing it?
Speaker:I'd say the biggest, um, collaborator with oxalate to, to
Speaker:really get you is the lectins.
Speaker:And so if you have a high lectin, high oxalate diet that will get you
Speaker:period, it will eventually get you.
Speaker:I just feel so strongly about that, that Yeah.
Speaker:And even if it doesn't get you, it doesn't mean that it's safe.
Speaker:So this is another principle that goes with this just on this.
Speaker:The first side is the end side.
Speaker:Like, oh, you're sick and now what do you do?
Speaker:And now you've done something.
Speaker:How do you know oxalate was the reason you're better?
Speaker:But on this.
Speaker:Coming into the disease side,
Speaker:you have to remember that toxins that cause disease don't cause
Speaker:the same disease in the same amount of time in every person.
Speaker:So if you think about tobacco exposure or the use of cigarettes, and that's
Speaker:a broader form of toxicity because the filters and the chemicals and the other
Speaker:things done when you make a cigarette adds to the possible and very well
Speaker:documented toxicity of smoking cigarettes.
Speaker:So we put warning labels on cigarettes and we restrict who can buy them and we add
Speaker:taxes to them to make an incentive for you to not use this product because we know
Speaker:it can cause problems like lung cancer.
Speaker:But does every smoker die of lung cancer?
Speaker:They do not.
Speaker:Very few, very few people who smoke die of lung cancer, very few.
Speaker:So does that mean we should all just smoke cigarettes and ignore that toxin?
Speaker:Apparently it doesn't mean that, but people use that logic when they
Speaker:think about something like oxalate.
Speaker:Well, uncle Charlie's been eating X, Y, Z his whole life and he's still cutting
Speaker:down trees and he's 78 years old.
Speaker:Okay, so therefore you can pick out on it or let your pregnant daughter do that,
Speaker:or let your child have it as baby food.
Speaker:I don't think so, because when something is toxic, it is toxic,
Speaker:and you cannot predict who can withstand the toxin and who cannot.
Speaker:So you wanna use a precautionary approach and say, you know what?
Speaker:We should find out what generally is a tolerable level of a toxin
Speaker:and try not to exceed that.
Speaker:And that's my whole message with my book is that.
Speaker:We're built to handle a hundred milligrams or maybe 200 milligrams max a day.
Speaker:But most of you're eating 600 or a thousand.
Speaker:And those of you on spinach, you could be doing 3000 a day.
Speaker:And if you're a sick, frail person or a little baby, you literally could
Speaker:kill somebody with that or give them permanent health problems with thyroid
Speaker:dysfunction and even, um, fibrosis of the lungs because the lungs will try
Speaker:to help the poor kidneys get rid of it.
Speaker:And the lungs is in that first three organs that get slammed with it after
Speaker:each meal, so you can get in trouble.
Speaker:So I just wanna say like, is it oxalates?
Speaker:Well, something that's toxic ought to be on our radar period.
Speaker:Now when you're sick like I am and you finally do a low oxalate diet, when
Speaker:it's oxalate, at some point you start to see the body expelling the oxalate.
Speaker:So you will see it as cloudy urine.
Speaker:Tartar on the teeth, gritty stools, uh, skin breakouts.
Speaker:Some people literally get boils that push out whole crystals.
Speaker:Other people start snowing with white dust coming off their
Speaker:skin periodically or constantly.
Speaker:Some people constantly for years, and you can tell, oh my gosh, I
Speaker:have oxalate overload and now my overloaded body is puking it up all
Speaker:over the place and you can see it.
Speaker:So you can detect this oxalate overload with the deaccumulation process.
Speaker:And the other way you know it's oxalate is 'cause when you change your diet,
Speaker:suddenly wonderful things can happen.
Speaker:You sleep better.
Speaker:You aren't running to the bathroom all night long, your
Speaker:bladder's functioning better.
Speaker:You stop getting bladder infections, you stop getting yeast infections, you stop
Speaker:getting sinus infections, your vision gets better, your hearing is better.
Speaker:Your teeth stop hurting, like something good can happen when you
Speaker:quit poisoning your body, it's.
Speaker:You can kind of tell the, the confusion is that people think, well,
Speaker:there's probably something else.
Speaker:But once you get a toxin, that's also making you nutrient deficient
Speaker:by the way, in minerals and so on.
Speaker:Once you lower your exposure to this toxin and you, it helps your whole
Speaker:mitochondrial system, your, your barrier function of your epithelial tissues, all
Speaker:these things start functioning better.
Speaker:And the other problems like your mold and this and that,
Speaker:start clearing themselves up.
Speaker:That's interesting.
Speaker:Little bit off script and probably maybe a slightly technical question.
Speaker:Uh, is there like a relationship, you mentioned yeast, so you just
Speaker:put, am I, uh, uh, I got interested.
Speaker:Uh, is your relationship between oxalates and uh, fungal infections
Speaker:like candida, do you think
Speaker:Yes.
Speaker:That oxalates make you vulnerable to these infections?
Speaker:Not that they're producing the oxalate necessarily.
Speaker:There is a slight chance that some bacteria.
Speaker:That are related to candida or they're promoted by a candida infection,
Speaker:might produce a little oxalate.
Speaker:But what's happening is that the oxalate is wrecking your barrier
Speaker:function and your immune function and your sitting duck for infections.
Speaker:It also causes acidity and pH problems, and that promotes, um, an environment
Speaker:that allows these infections to occur.
Speaker:Yeah, no, that, okay, that makes total sense.
Speaker:I'll do some more research on that ortho there.
Speaker:But no, it was just something that, uh, just struck me as
Speaker:being a potential length there.
Speaker:Uh, there's only
Speaker:certain, there's only certain molds that produce oxalate and
Speaker:most of them are soil molds.
Speaker:And candida is a yeast that is not known to produce any oxalate.
Speaker:So it's not a direct, it's the other way around.
Speaker:It's that oxalates help create an environment where
Speaker:you get candida infections.
Speaker:Okay.
Speaker:I've learned something.
Speaker:Thank you.
Speaker:Yeah.
Speaker:Um, I suppose sort of the natural progression of this question
Speaker:would maybe be to talk about something like oxalate testing.
Speaker:Um, there are a bunch of different options out there.
Speaker:You, you get serum and urinary direct sort of, uh, test look at, uh, on oxalate.
Speaker:And then you've also got your organic acids tests that are looking
Speaker:at urinary oxalate metabolites.
Speaker:Um, do you think that these tests are, are clinically useful for individuals,
Speaker:uh, from a clinical point of view?
Speaker:Maybe helping them to sort of identify, um, whether oxalates are, again, are,
Speaker:are, are maybe for them genetically more of an issue than for somebody else?
Speaker:Um, do you think that Yeah.
Speaker:Do you think that they're useful in that they have a, a purpose or again, is it.
Speaker:Are oxalates sort of detrimental to the point where we should all
Speaker:just be eliminating as much of them from our diets as possible?
Speaker:Uh, as a general of thumb, if you get my understanding there.
Speaker:Right.
Speaker:So there's again, different agendas at play and how important testing is.
Speaker:Culturally testing has become very important.
Speaker:Patients want some validation that says, here, see this is really
Speaker:a real thing and see it's in my urine and it's seriously high.
Speaker:And that gives them, um, a pass for not being nuts with their husbands or their
Speaker:children or their doctor or something.
Speaker:So patients want that validation because they wanna know something
Speaker:really concrete and physical is wrong with them, rather than being
Speaker:told they're just anxious and crazy.
Speaker:So it has that value potentially if you don't get the false negative results.
Speaker:But I, for example, when I did the organic acids test in 2009, had
Speaker:absolutely no oxalate problem whatsoever.
Speaker:According to the test.
Speaker:Not anything was showing up, nothing completely clean.
Speaker:Bill of Health, I was so poisoned with oxalate and had been most of my life.
Speaker:And yet the test doesn't catch it.
Speaker:And this is the problem with assuming that biology is like an object on the desk.
Speaker:You cannot, you cannot expect your urine to, to be like a pen.
Speaker:That never changes except for the, it comes out, it's constantly
Speaker:in flux based on all kinds of metabolic priorities going on.
Speaker:The kidneys are very active.
Speaker:It's not just a blood filtering system.
Speaker:It's a whole, um, management of your metabolism going on with kidneys.
Speaker:There, there are major drivers of metabolism, major communicator about
Speaker:what's going on in the body, and they wanna do different things at night
Speaker:versus the morning versus after meals, versus in the spring or during Equinox.
Speaker:Like there's a lot going on.
Speaker:That causes a lot of variability.
Speaker:And one of the main things that the body does is help the kidneys not be constantly
Speaker:abused by too much oxalate all the time.
Speaker:So literally there's kind of like weekends where you get a little break and that
Speaker:break might always be at 10 in the morning when you took your test or something.
Speaker:Like there's these cycles going on, which we don't have a clue
Speaker:how this is so complicated.
Speaker:Maybe some SU supercomputer in the future will get a better sense
Speaker:of how the body is so brilliant.
Speaker:But to take a static test and say, oh no, oxalate problem, you can't do that.
Speaker:Now if you get a test that shows elevated oxalate and EL elevated
Speaker:all kinds of stuff that's oxalate metabolism related, then you wanna
Speaker:really believe that that is for real.
Speaker:Yeah, yeah.
Speaker:No, it's uh, yeah.
Speaker:So essentially it's not really.
Speaker:Let me see if I can get this right.
Speaker:You're not likely to get a, a false negative, but you should likely to get
Speaker:a, a false negative, a real positive, but you should not ignore a false positive.
Speaker:Positive.
Speaker:Don't ignore it.
Speaker:If you
Speaker:don't get a positive, you don't necessarily know anything.
Speaker:Yeah, that, that's fair enough.
Speaker:No, I, you can't
Speaker:like eliminate an oxalate problem by a test.
Speaker:Alright?
Speaker:Yeah.
Speaker:You can only
Speaker:eliminate an oxalate problem by doing the diet correctly, long enough.
Speaker:To see if it's making any difference.
Speaker:Yeah.
Speaker:And, and just out of interest, um, well actually, you know what, we
Speaker:can tie that into the next question, um, which I suppose sort of brings
Speaker:us around to sort of how to start getting, uh, rid of ox isolate safely.
Speaker:I know you, we've already, you've already touched on that with regards to sort of
Speaker:oxalate dumping and the fact that, um, if you do it potentially too quickly,
Speaker:maybe you can al almost end up with these, well, you can end up with these
Speaker:sort of her summer esque like reactions where the body actually starts to excrete
Speaker:oxalates every which way, uh, possible.
Speaker:And that can, as you mentioned earlier, sorts of, uh, manifest as, as skin issues
Speaker:as a worsening of current symptoms.
Speaker:Um, what in your mind, I suppose, no, not in your mind, um, it's a bit generic.
Speaker:You are the expert here.
Speaker:How would you.
Speaker:Um, counsel, an individual who has a high oxalate level to start weaning
Speaker:down and reducing the level of oxalates in their body so that they don't
Speaker:necessarily have these sort of very adverse reactions or those to some extent,
Speaker:uh, can you not get away from them?
Speaker:Well, first of all, you have to accept that this is a learning process.
Speaker:It's an education process.
Speaker:You have to get educated.
Speaker:You have to take the time to learn, and you can't just be given three tips and
Speaker:you're ready to roll and get in action.
Speaker:With ignorantly you, you don't wanna be a soldier following orders.
Speaker:You wanna be a informed person.
Speaker:So you're gonna need to take time to even examine your diet and think about, well,
Speaker:how much potatoes you've been eating.
Speaker:If you're using too much quinoa, beets, or these dark leafy greens,
Speaker:these three ones that are high in Oxley, other ones are fine, but
Speaker:you need to get to know the data.
Speaker:And you can't just do a Google search because there's a lot
Speaker:of bad stuff on the internet.
Speaker:I do have some free stuff on my website, toxic Superfoods.
Speaker:The book has many lists in there that are simple, and if you want detailed
Speaker:data, I've assembled it in a book you can buy just on my website, and you
Speaker:can learn and you can get a quick sense of like what things are high and low
Speaker:by just looking at the color coding.
Speaker:Things that are, uh, white, green, or yellow are fine, but the things
Speaker:that are in the darker orange in.
Speaker:Red are things you need to be really thinking about.
Speaker:Are you eating them?
Speaker:So you can think about your diet, what you've been doing recently,
Speaker:what you seem to like do doing, and find these worst offender foods and
Speaker:pick one that you can live without and learn how to live without it.
Speaker:Like Swiss chard who can live without Swiss chard, like get, just get practical.
Speaker:And so you start to learn what those are, and you start to be, 'cause you're
Speaker:modifying your shopping cart, your cooking habits, what you order when you eat out.
Speaker:Your whole life rhythm can be built around your meals and your meal prep
Speaker:and meal planning and your budgeting.
Speaker:So it's important to start thinking in that way.
Speaker:Like, how does a human being gradually change in their habits, in their thinking?
Speaker:So give yourself some patience.
Speaker:That's the main thing.
Speaker:I know we wanna just talk, well, you know, the science part and
Speaker:so on, but it's really important that you're a human being.
Speaker:And you are a microbiome, like you're also changing your microbiome whenever
Speaker:you change your diet in any way.
Speaker:And the more gently you can do that, the better.
Speaker:Now your body's been dealing with every meal you've been eating, some probably
Speaker:oxalates at most meals, and these waves of meals are keeping your blood level high.
Speaker:And when you start taking these foods out, the amount of oxalate
Speaker:in your bloodstream comes down.
Speaker:If it comes down really abruptly, the body can hear.
Speaker:That's a signal, right?
Speaker:That's a signal.
Speaker:Big high oxalate.
Speaker:Very little oxalate.
Speaker:And you stay little oxalate for just three days.
Speaker:It's all it takes for the body to go, oh, the bloodstream is open.
Speaker:It's an open, it's open area.
Speaker:We can now get it out of the thyroid gland.
Speaker:Yay.
Speaker:And then you bring in inflammation and try to bring on a thyroid gland.
Speaker:So you look at your worst offending foods and decide that you can live without
Speaker:peanut butter, Swiss chard, almonds, almond milk, almond, this and that.
Speaker:Cashews, fake cashew cheese.
Speaker:And you keep picking them off one by one.
Speaker:And basically you wanna get a sense of, well, wow, I've been eating over
Speaker:800 milligrams on a typical days.
Speaker:And on days when I do my double fudge whatever brownies, I'm at 1500 and
Speaker:on the days I do my spinach smoothie on Saturday mornings, I'm at 2,500.
Speaker:Like, then you can just knock off the 2,500 days.
Speaker:You wanna get out of that toxic danger zone of a consumption and bring it down.
Speaker:And if even if you bring it down to like 200, even 400, you can start to benefit
Speaker:without maybe, um, inspiring a riot.
Speaker:You might say, the teacher's like, yeah man, we could get rid of this stuff.
Speaker:You don't really, you want, it's better to leave all this accumulation where it
Speaker:is and just stop accumulating and stop flushing all your organs in your vascular
Speaker:system meal after meal after meal.
Speaker:And you could do it another way.
Speaker:You could do it or just say, I wanna make sure.
Speaker:Every breakfast is oxalate free, or every dinner is is low oxalate.
Speaker:Um, and learn how to do that.
Speaker:So there's a, there's a whole individual process, like what works for your
Speaker:lifestyle, your personality and your family, how you actually do it.
Speaker:But what all you need to know is that this is not a hundred percent elimination diet.
Speaker:This is not a gluten-free allergy thing whatsoever.
Speaker:This is about toxicity.
Speaker:You have to get out of that really toxic zone.
Speaker:And so that means almost any high oxalate food could be reintroduced
Speaker:because you could go back to having hot cocoa if all the other
Speaker:oxalate foods are outta your diet.
Speaker:There's room for any of them, but just get rid of the ones you know you can
Speaker:live without, and then start getting.
Speaker:Uh, gradually moving towards a, a sensible diet that's gonna work for you,
Speaker:hopefully not triggering the excessive deaccumulation that can be create an
Speaker:illness because you could literally cause disruptions in the ions in your blood.
Speaker:'cause you're putting acid back in your blood.
Speaker:You drop the calcium levels as it grabs that calcium.
Speaker:You have hypocalcemia, which can cause pacemaker problems, arrhythmias,
Speaker:super spikes, and hypertension.
Speaker:And you feel like you're having a heart attack because you're
Speaker:having electrolyte crises.
Speaker:You may be acting like you've had a stroke and dragging your left side around.
Speaker:Uh, it can get really serious when you mess up your blood electrolytes
Speaker:and have this inflammation going on at the same time.
Speaker:Yeah, I, I suppose, well, what I've taken from that is age,
Speaker:it, it probably shouldn't be sort of this binary execution.
Speaker:IE don't just jump straight onto a carnival diet if you think
Speaker:you've got an oxid overload.
Speaker:Uh, and B um, yeah, as you've, uh, just alluded to.
Speaker:Yeah, just take it slowly.
Speaker:Um.
Speaker:Supplements, I think.
Speaker:Uh, you mentioned calcium.
Speaker:Um, the other one that springs to mind is vitamin B six, um, which I
Speaker:know is involved in the clearance of, of, uh, oxalate, specifically BB six.
Speaker:If I, my biochem is correct.
Speaker:I think it helps convert gly oxalate into glycine instead of oxalate.
Speaker:I think, uh, right back
Speaker:and forth, it's, I think it's on both enzymes.
Speaker:It can turn glycine to oxalate or turn oxalate back into glycine.
Speaker:Okay.
Speaker:Um, and, or, you know, hydroxyproline, which is more likely, but you also have
Speaker:B one or thiamine is turning oxalate into non-toxic chemicals without
Speaker:enough B one, well, not oxalate.
Speaker:See, what we're, the mistake we're making is, is this, this precursor to oxalate,
Speaker:this precursor, there's actually three glyoxal, oxalate and so on that are
Speaker:in there that are toxic in themselves, acidifying themselves, but there.
Speaker:There are precursor these, these enzymes can shunt that and protect
Speaker:that from becoming all oxalate.
Speaker:If you have the co-factors, that's what vitamins are.
Speaker:They're co-factors on the enzymes that make metabolic transformations
Speaker:in turn one molecule into a different kind of molecule.
Speaker:So you need these B vitamins on these transforming proteins so
Speaker:they can protect us from excessive production of oxalate in cells.
Speaker:Um, the liver, the kidney and red blood cells are may
Speaker:mostly where this is happening.
Speaker:That doesn't really protect you from the excessive vitamin C that can just turn
Speaker:into oxalate without even enzymatic.
Speaker:Both vitamin C, there's both enzyme pathways that turn it into
Speaker:oxalate and there's just transfer, just spontaneous, like literally
Speaker:in a vitamin bottle of vitamin C.
Speaker:It can turn into oxalate just sitting there.
Speaker:Um, so the vitamin C is interesting because it gets into all cells.
Speaker:And if any cell in the body can accumulate vitamin C and start
Speaker:having oxalate formation in the cell with or without the enzyme.
Speaker:So that's where the B vitamins are not protecting you from
Speaker:that vitamin C necessarily.
Speaker:So yeah, the supplements are very important.
Speaker:We've now created a mineral deficiency by overeating oxalate, and calcium is
Speaker:the binder that helps you remove oxalate from the body safely and gives it a whole
Speaker:lot of buffering capacity to handle these wobbling hypo calcium attacks that happen
Speaker:as your body's trying to release oxalate.
Speaker:So you need a lot of calcium, and the supplement form is
Speaker:excellent for doing this.
Speaker:It is the number one medicine for people who are oxalate poisoned, does not
Speaker:cause calcification of your arteries.
Speaker:Calcification of the body is because of what we talked about
Speaker:before where the cells are damaged and now they're turning into bone
Speaker:cells, and that's the damage side.
Speaker:The calcium helps prevent further damage that the supplement calcium,
Speaker:so alkaline minerals, with calcium being the main one, potassium is being
Speaker:leaked out and lost in the process.
Speaker:So potassium's very important.
Speaker:Most people are deficient in it.
Speaker:Usually we, there's a need for magnesium and often we like to
Speaker:see these in a citrate form.
Speaker:You can also use some of them in a bicarb form because there's a lot of acidity
Speaker:going on, and the alkaline minerals help address some of that acidity.
Speaker:The bicarb helps doing that.
Speaker:And then there's citrates.
Speaker:So citric acid comes from lemon juice, but we also use citrates to deliver
Speaker:these minerals and supplement forms.
Speaker:So often we suggest you start with the citrate form of.
Speaker:At least the calcium or the um, you can do that with magnesium as well and so on.
Speaker:But you can play around because it's a separate issue.
Speaker:But the citrate prevents crystal growth and helps the hard crystals that are
Speaker:hard, like quartz, it softens them because citric acid has such a strong affinity
Speaker:for calcium that it's even stronger than the oxalate affinity for calcium.
Speaker:So when it sits on a calcium oxalate molecule income citrate, it actually
Speaker:loosens the bond between oxalate and calcium and makes it more chalky, softer,
Speaker:and then you can break it down easily.
Speaker:So it destabilizes that sort of crystal light, obviously
Speaker:cleaved off.
Speaker:Yeah.
Speaker:Crystal.
Speaker:Yeah.
Speaker:So it's really just weakening the bonds.
Speaker:Yeah.
Speaker:But it turns quartz into chalk so you can get rid of it.
Speaker:So the citrates are really great and.
Speaker:Um, when the cells have the right pH they can generate citrate themselves and the,
Speaker:the urine needs to be high in citric acid.
Speaker:That would be a good test to run, is how much CI citrate your kidneys
Speaker:can put out, um, because that's protecting you from kidney stones.
Speaker:So if people with a history of kidney stones, we might look at that.
Speaker:Um, so those are the main things where you can use B vitamins,
Speaker:the minerals and citric acid.
Speaker:Those are the main ones.
Speaker:And then there's other things that can help along the way comes to
Speaker:EDTA, et cetera.
Speaker:Yeah, and just, just generally supporting the damage nervous system with things like
Speaker:choline or, it depends on that person's issues, but e even, you know, occasionally
Speaker:needing aspirin, things like this 'cause there's so much inflammation going on.
Speaker:So you need a little bit of support, but I like to use.
Speaker:Is few oral things.
Speaker:You can even use mineral baths and topical things to really support this
Speaker:process if people's, oftentimes you have problem with digestion with these folks.
Speaker:'cause you almost always have some digestive dysfunction, either because
Speaker:the nerves aren't working right and now the muscles of the sphincters
Speaker:are damaged in their function or the whole, um, many of the tissues
Speaker:in the gut are a little distressed.
Speaker:There's, there's immune tissues and just the general absorptive
Speaker:surface is, is not good.
Speaker:And then you have potentially some problems with bile production,
Speaker:uh, production of anything from the pancreas, including your
Speaker:insulin, but also the digestive.
Speaker:Enzymes and so on.
Speaker:So it depends on what's going on, what other supplements might be useful.
Speaker:Yeah, and I think what's important to take away for the listener is that,
Speaker:uh, what, what you've just alluded to can does and can get very complicated.
Speaker:But at a high level, if you just start to slowly reduce the total oxalate,
Speaker:uh, your total oxalate intake, you are very likely to sort of resolve
Speaker:the majority of these issues without necessarily needing to get to this point.
Speaker:Especially if you're still in the, in, in the state where you are
Speaker:not feeling a hundred percent, but you're not necessarily in that.
Speaker:Um, I can't get out Bed Point.
Speaker:The earlier the better.
Speaker:Yes, of
Speaker:course.
Speaker:So
Speaker:because this is really, those of us who've really messed up our lives with oxalate
Speaker:would, would just wish to not have anyone go through what we've been through.
Speaker:This can be very devastating and bring people to the brink of
Speaker:serious problems that could be.
Speaker:Yeah.
Speaker:Very hard to live with.
Speaker:And the, the recovery process is not quick.
Speaker:It might be 10 or 15 years of recovery.
Speaker:Yeah, no, um, yeah, you, you, you've got to rebuild the body
Speaker:at, uh, at a cell by cell level.
Speaker:Yeah.
Speaker:Um, Sally, I know we're starting to run short on time, but sort of
Speaker:end off with, I'd love to ask you just a few rapid ish fire questions.
Speaker:These never end up being rapid fire, but we'll try, we'll do our best.
Speaker:See
Speaker:if we can win the game.
Speaker:Yeah.
Speaker:We'll, we'll do our best.
Speaker:Um, the first one is going to be about as rapid as my, as I am first thing
Speaker:in the morning with our caffeine.
Speaker:Um, but, and this is, is something we had discussed previously, but
Speaker:why isn't this a bigger issue?
Speaker:Uh, why isn't this being, uh, sort of looked at?
Speaker:More at, at a more institutional level.
Speaker:Um, why is it being swept on the rug?
Speaker:And I, I'm sure we could get somewhat conspiratorial, but, um, at, at the, yeah.
Speaker:What are your thoughts on that?
Speaker:Well, the
Speaker:fast answer is read my book.
Speaker:There's a chapter on this and it talks about the failures in medicine and
Speaker:nutrition and so on of ignoring this.
Speaker:And some of it literally, the system is rigged to keep disease processes going
Speaker:because researchers need careers and you can't solve the problem you're, you're
Speaker:studying because then you're out of a job.
Speaker:Yeah, no, that makes total sense.
Speaker:Okay, nice and simple.
Speaker:Next one.
Speaker:Um, what's the one high oxalate food that's, uh, people would be
Speaker:surprised to learn is problematic?
Speaker:Well, buckwheat, quinoa, chia seeds.
Speaker:I would say most people are shocked at the spinach one, but anyone who knows anything
Speaker:about nutrition is not shocked about that.
Speaker:So if you're shocked, go back to 1 0 1 nutrition class 'cause
Speaker:hello and brand is another one.
Speaker:But brand was fashionable in the eighties, I guess it's a little
Speaker:fashionable again, but those are key ones.
Speaker:And I would say generally gluten-free stuff, almost always
Speaker:high oxalate and keto stuff.
Speaker:The chocolate and the, the almonds and so on.
Speaker:Yeah.
Speaker:Yeah.
Speaker:No, I, I was going to, I was, my pick for that would've been chocolate.
Speaker:I think most people ah, yeah.
Speaker:Get, get a nasty surprise when you say, uh, that 90% lin that you're eating.
Speaker:Yes.
Speaker:It's low in sugar, but it's
Speaker:high in lead.
Speaker:Cadium and oxalate.
Speaker:There we go.
Speaker:Yeah.
Speaker:But I try not to break that news because I don't wanna get hit or shot.
Speaker:Yeah, it's, uh, it's, you are dancing the fire a bit there.
Speaker:Um, well here's another one.
Speaker:Oh, another one.
Speaker:Let's,
Speaker:mm-hmm.
Speaker:Turmeric.
Speaker:Yes, of course.
Speaker:Yeah.
Speaker:And I think you can back up the whole word, turmeric, but yeah.
Speaker:Coaching co and
Speaker:extracts are not, yeah.
Speaker:So if you're interested in playing with the extracts, there are no problem.
Speaker:Perfect.
Speaker:Um, what's the most common misconception about oxalates that
Speaker:you encounter on a day-to-day basis?
Speaker:Oh, most common misconception about oxalates?
Speaker:Well, you have to have renal failure or kidney stones for it to matter.
Speaker:If you haven't had a kidney stone, you can have all you want.
Speaker:No, you have a lot of other tissues that care, including your precious teeth and
Speaker:your eyes and your thyroid gland, and your vascular system and your immune cells.
Speaker:Send your liver and a few other things.
Speaker:Your desire to live.
Speaker:Yes.
Speaker:Your
Speaker:desire to live and not be feeble and not be old before your time.
Speaker:Because I believe knowing about oxalate and getting 'em out of your
Speaker:life, you found the fountain of youth.
Speaker:Yeah.
Speaker:No, I couldn't agree more.
Speaker:And the last one, um.
Speaker:Maybe a bit of a controversial one and something we've already discussed
Speaker:in passing already, but what do you think about the carnivore diet,
Speaker:uh, in relation to all of this?
Speaker:The carnivore diet is an excellent demonstration of the need and value
Speaker:of meat products, meat in the diet.
Speaker:It's also a very handy elimination diet that'll help you, um, take a
Speaker:break from lots of chemicals and lots of confusion about what dietary things
Speaker:might be influencing your health.
Speaker:The thing is too long in a carnivore diet could actually increase your
Speaker:intolerance potentially if have oxalate poisoning to some plant foods.
Speaker:So I don't know if that's really true.
Speaker:We really need research on that.
Speaker:Um, and.
Speaker:It is essentially a zero carb diet and day in and day out.
Speaker:A zero carb is gonna be kind of rough.
Speaker:You're gonna have some degree of insulin sensitivity, so it's gonna take a while
Speaker:to get you tolerant to some carbs.
Speaker:Again, if you're needing to go back and diversify your
Speaker:diet, you need to be patient.
Speaker:But I, I really love that people seem to be thriving on carnivore because
Speaker:too many people are undereating protein guys who are working out like crazy.
Speaker:Mm-hmm.
Speaker:And aren't putting on bulk because they want only like
Speaker:three ounces of meat twice a day.
Speaker:That's not enough meat.
Speaker:Yeah.
Speaker:To me,
Speaker:I think you need five ounces, two or three times minimum.
Speaker:Like, I'd like to see people be more comfortable with meat and protein.
Speaker:Yeah, I think sort of aim for that one gram of, uh, protein per per
Speaker:kilogram, per pound of body, uh, weight is a reasonable assumption.
Speaker:Um, whether it's lean mass or not is up for debate.
Speaker:But yeah, no, I definitely, I couldn't agree more.
Speaker:The RDA on on protein is woefully low, and especially as we start looking
Speaker:at all the populations that already have protein malabsorption issues and
Speaker:assumingly, um, oxid issues like elderly.
Speaker:Yeah, yeah,
Speaker:for sure.
Speaker:Yeah.
Speaker:And I'm just shocked at how many people work out multiple times a
Speaker:day and they won't eat protein.
Speaker:Like, mm. You could look extra cute if you ate.
Speaker:Just don't eat the whole thing.
Speaker:Eat enough.
Speaker:So that's, um, the beautiful thing about carnivore is that people can pile their
Speaker:plates with animal foods and thrive on it.
Speaker:Yeah.
Speaker:It
Speaker:seemingly,
Speaker:uh.
Speaker:I, I'm, I'm definitely looking forward to seeing some longer term EC data there.
Speaker:Um, I mean, Reddit is obviously full of, um, and some, potentially some
Speaker:studies, but I think the anecdotal evidence will come first, um, of
Speaker:people who have been on this diet 5, 10, 15, 20 years, uh, en masse.
Speaker:I mean, obviously you've got your, your Sean Bakers of the world.
Speaker:Um, but I think they are more the exception than the rule.
Speaker:If I can interrupt you and say, the biggest downside of carnivore is
Speaker:that chronic ketosis means chronic low grade acidity, which breaks down
Speaker:your connective tissue and promotes osteoporosis and maybe cancer.
Speaker:So I really think you're gonna end up with connective tissue issues.
Speaker:Your old tennis elbow and your old football injuries are gonna come back
Speaker:and kick you hard if you're not at least correcting the pH and not getting
Speaker:enough minerals, and maybe even just getting outta ketosis once in a while.
Speaker:But I, I do think the downside of chronically using an
Speaker:elimination diet like that.
Speaker:Is, um, quite serious.
Speaker:If, again, if you wanna be fit and healthy, you may lose your
Speaker:ability to have a healthy joint.
Speaker:And bones.
Speaker:Yeah, in
Speaker:theory,
Speaker:I think some of that, and this has definitely turned into a
Speaker:very un rapid fire question.
Speaker:Um, sorry.
Speaker:No, it's my fault as well.
Speaker:Uh, could be mediated by that ingestion of protein and, and then the breakdown
Speaker:or that protein into sugar through gluconeogenesis and all of that.
Speaker:But no, fundamentally, I do completely agree with you.
Speaker:I, I think that, um, if you look at it sort of from an evolutionary
Speaker:anthropological, uh, sort of whatever term best, uh, you best identify with,
Speaker:um, viewpoint, you'll sort of note that people sort of ate seasonally.
Speaker:They went in and out of these, um, these dietary patterns.
Speaker:Uh, nobody stuck to anything.
Speaker:Uh, at least again, based on my view of the literature, literature
Speaker:indefinitely, there was, there were always sort of shifts in
Speaker:and outta these dietary patterns.
Speaker:Um, which I think sort of speaks, speaks volumes to how we
Speaker:should eat, generally speaking.
Speaker:Anyway.
Speaker:Um.
Speaker:For this, uh, yeah, caveat being exclude Ox Oxfords.
Speaker:But yeah, Sally, um, you've been an absolute angel and a star and thank
Speaker:you so much for this conversation.
Speaker:Um, I have a feeling that this is a, a pretty easy one to answer 'cause
Speaker:all people really need is Google.
Speaker:But, um, where's the best place that people can find you?
Speaker:Sally key norton.com.
Speaker:Sally key norton.com is my website.
Speaker:There's a lot of free information there.
Speaker:There's free downloads.
Speaker:That's the only place you can get the data for oxalates.
Speaker:Don't try to get some knockoff off Amazon.
Speaker:Um, and you can find me on Instagram mostly for social media.
Speaker:I don't spend a lot of time on the other channels much, but
Speaker:I also have a YouTube channel.
Speaker:I really encourage people to come visit Sally k Norton, the,
Speaker:or It's SK Norton, either one.
Speaker:Uh, YouTube channel where we have testimonials.
Speaker:We have about 13 there.
Speaker:We have about 22 shorts.
Speaker:These are just little one minute videos and you may find one or two
Speaker:in there that will help you help somebody else discover this topic.
Speaker:Those little one minutes you could probably barter for
Speaker:one minute of someone's time.
Speaker:So, uh, hopefully you're using that YouTube video channel of
Speaker:mine to, uh, help other people
Speaker:of course benefit.
Speaker:Yeah.
Speaker:And we'll be sure to link to all of that in the show notes when
Speaker:the, the podcast is obviously live.
Speaker:Sally, thank you so much again.
Speaker:I really do appreciate it.
Speaker:Thank you.
Speaker:It's wonderful to be with you and I'm so glad your audience is gonna
Speaker:take an interesting in oxalate.
Speaker:Thank.