The thing is, people always ask me, like, what's the one thing I should do?
Speaker AThere is no one thing.
Speaker AThe one thing is sunblock, probably if there's a one thing really depends on how old you are.
Speaker AYour skin quality, your facial structure, your budget, you know, your comfort level with trying new things.
Speaker AThere's so many variables.
Speaker BShould we be eating all organic?
Speaker AI'm sure that people in my wellness world want to hang me for this, but I think that the jury is still out.
Speaker BYou know, I'm so glad you brought up sexual health, because I think that that is such a topic that women don't feel comfortable talking about all the.
Speaker AThings that are in your.
Speaker AIn your head.
Speaker ABecause we know that your brain is your largest and most sex organ.
Speaker ASo you start with there.
Speaker ASo start with the mind.
Speaker BWhat are the signs that women should look for to see if their hormones are off?
Speaker AAll women should be getting basic hormone testing at least once a year.
Speaker AAnd that's like thyroid.
Speaker AThat's, you know, if you're over 35 or so, probably testosterone.
Speaker AYeah.
Speaker AI mean, unfortunately, doctors just don't receive training, you know, very much training at all in any of this stuff.
Speaker AEven the gynecologist, even the endocrinologist.
Speaker AConsistency.
Speaker AYou don't have to go hard every day.
Speaker AYou just gotta go.
Speaker BToday's guest is one of the boldest, smartest, and most forward thinking voices in women's health and regenerative medicine.
Speaker BDr. Amy Killen is a board certified physician and expert in anti aging, hormone optimization, aesthetics and sexual wellness.
Speaker BAnd she's not afraid to talk about the stuff most doctors avoid.
Speaker BIn this episode, we break down the science behind midlife aging.
Speaker BFrom hormones and libido to peptides, PRP and exosomes.
Speaker BWe talk about what actually works, what's just clever marketing, and how to advocate for your body when the system keeps telling you you're fine.
Speaker BWe also go deep on why so many women are misdiagnosed or ignored.
Speaker BWhat's really driving, low energy, low sex drive, and accelerated aging.
Speaker BAnd how regenerative medicine is rewriting what's possible for women in midlife and beyond.
Speaker BThis conversation is smart, grounded, and packed with information you're not getting from your average doctor or your for you page.
Speaker BFollow the iconic Midlife wherever you get your podcasts and send this one to the friend who's wondering if it's just hormones or something deeper.
Speaker BAmy, welcome to the Iconic Midlife.
Speaker BSo excited to have you today.
Speaker BThank you so much for joining us.
Speaker AYeah, thanks for having me.
Speaker AI'm excited to be here.
Speaker BGreat.
Speaker BHow's your day going so far?
Speaker AIt's been busy already.
Speaker AI was up early today, but so it's good.
Speaker BI saw you were at a lake, I think yesterday.
Speaker BIs that right?
Speaker BYou were traveling?
Speaker AOh, yeah.
Speaker AI was just.
Speaker AIt's like an hour from my house, so it wasn't that big of a travel.
Speaker ABut yeah, we go there every year.
Speaker AIt's amazing.
Speaker BOh, that sounds so refreshing and so nice.
Speaker BRight now.
Speaker BI could use a lake.
Speaker BI'm in Texas right now.
Speaker BIt's a little hot.
Speaker ATexas is hot.
Speaker BIt is, it is.
Speaker BParticularly in August.
Speaker AYep.
Speaker BAmazing.
Speaker BSo I would love to dive right in.
Speaker BYou know, I opened up my DMs to my followers and the amount of questions that we got blew my mind.
Speaker BI mean, there's so many things to discuss.
Speaker BYou know, I feel like midlife is sort of one of those times of life where, you know, you kind of go into it, you don't really know what's happening.
Speaker BAnd so just trying to find your way.
Speaker BSo I just, you know, I wanted to start with kind of, you know, your expertise and your background.
Speaker BAnd I love that you talk so much about regenerative medicine.
Speaker BThis is so important, you know, and it really.
Speaker BAs the future of aging.
Speaker BSo for some women in midlife who were just hearing that term for the first time, can you talk a little bit about what regenerative medicine is?
Speaker AYeah, regenerative medicine basically just means using tools.
Speaker AThere's various tools we could talk about, but getting your body to repair itself, to heal itself in.
Speaker AIn sort of novel ways.
Speaker ASo essentially, whether we send growth factors in from PRP or from stem cells or even like, light therapy or.
Speaker AOr other things like that, essentially getting your body to be like, oh, I actually need to start repairing this tissue and wake up and act like more youthful version of, you know, myself.
Speaker BAnd how does that differ from, like, what we've been taught, you know, with health, especially with women's health?
Speaker BLike, how is that different from, like, our mom's generation or Even our generation 10 years ago, you know?
Speaker AWell, we use regenerative medicine.
Speaker AYou know, it's most.
Speaker AIt's most commonly used for, like, repairing, you know, a hurt knee or shoulder injury.
Speaker ALike musculoskeletal pain is where we start.
Speaker AThis is where it started is using like, stem cell therapies and similar to repair muscle, muscle tissue, you know, tendons, ligaments.
Speaker ABut I've been using regenerative therapies for.
Speaker AFor skin health, for scalp health, so to help regrow hair, for sexual Health and even for potentially kind of longevity purposes for the last 10 years.
Speaker AAnd it's all the same.
Speaker AYou know, we're using the same kind of technologies and biologics, but we're trying to kind of kind of approach aging and healing in a different way.
Speaker BYou know, I'm so glad you brought up sexual health, because I think that that is such a topic that women don't feel comfortable talking about with their doctors, with even their friends, you know, their partners.
Speaker BSo I think that that is such an important thing to talk about.
Speaker BSo as it relates to aging and clinical health, what are some ways that we can help improve our sexual health, you know, and not feel so ashamed and like, stigmatized about talking about it?
Speaker AYeah, I mean, I think sexual health is.
Speaker AIt's just like any other health, right?
Speaker ALike, we, we should, we should be able.
Speaker AWe go to the doctor.
Speaker AWe have, you know, my knee is not working properly, and it's no big deal.
Speaker ABut like, we don't want, we don't go to the doctor and say, my clitoris or my vag.
Speaker AWe were very nervous about, say, like, this other area is not working properly.
Speaker ASo part of it is just kind of getting over that.
Speaker ABut, you know, I think of sexual health as being kind of.
Speaker AI have kind of a four pronged approach to sexual health.
Speaker ASo the first one is mind.
Speaker AThe mind.
Speaker ASo you always start with thinking about the brain, whether that's, you know, social relationships, that's your stress, that's your past trauma, like all the things that are in your.
Speaker AIn your head.
Speaker ABecause we know that your brain is your largest and most important sex organization.
Speaker ASo start with there.
Speaker ASo start with the mind.
Speaker AAnd then the second part of it is boost blood flow, you know, blood flow to the sexual organs.
Speaker AWe know in men it's super important for, you know, for erections to have blood flow.
Speaker AAnd in, actually, in men, the most common cause of sexual dysfunction is lack of blood flow, because we can see it like that's what causes lack of erections.
Speaker AWhat's interesting is that in the women, that's probably also one of the most common causes of sexual dysfunction, but it's not talked about in women because it's harder to measure in women.
Speaker ASo, but, but blood flow is very important.
Speaker ASo anything you can do to help with your, you know, cardiovascular health is going to be helping with your sexual health as well.
Speaker AThen the third piece of that is hormones, so making sure that your hormones are optimized.
Speaker AAnd then the fourth piece is the actual structures themselves and, you know, making sure the pelvic floor muscles are, you know, appropriately tight and making sure that you're all the structures themselves, the vagina, the clitoris, et cetera, are all in working order, if you will.
Speaker BSo where should.
Speaker BBecause that is like, like a very needed approach.
Speaker BWe need to do all four of those things.
Speaker BWhat do you think is the most important place for a woman to start when it comes to sexual health?
Speaker AI mean, I think it's very dependent on what's going on.
Speaker AYou know, women's sexual health is, is, is extremely complicated.
Speaker AIt's not just as easy as taking a Viagra and everything is perfect, you know, So I, I, I think the, the first place to start if you're by yourself, is to start, you know, thinking about, you know, easy things are, Start thinking about how stress is affecting your sex life, how lack of sleep, how you're, you know, lack of exercise, like some, like how the, how you're, the way that you feel about yourself.
Speaker ASome of these things are much more in our control than other things.
Speaker ABut just keeping in mind that, that the daily practices like that can make a huge difference in how, you know, whether or not you're, you have a libido or not, or, you know, how, how your arousal is coming across.
Speaker BWhat do you think is the most misunderstood thing about women's libido?
Speaker BLike, is there like a certain, almost like a mythbuster?
Speaker BYou know, I think a lot of.
Speaker AI think people think that women don't, don't have as much libido as men.
Speaker ALike, we're not as interested in sex as men.
Speaker AAnd that is true sometimes, and certainly it waxes and wanes throughout our lives.
Speaker AI think that it's totally normal to have some periods where we're not interested in sex and some periods where we're much more interested.
Speaker AAnd it kind of comes and goes.
Speaker ABut I think that women do get this, they get kind of a bad rap is like, we're not really that interested in insects.
Speaker ABut I think that's, that's not true a lot of times.
Speaker AYeah.
Speaker BAnd I think it's like you're saying it's, it's a multifaceted approach.
Speaker BAnd I love your idea of like, treating the body holistically as it relates to sexual health because it is so important to kind of prioritize yourself, take care of your fitness and your wellness, while also, you know, just like, really looking at your body as a whole.
Speaker AYeah.
Speaker AI mean, you know, we, we know that there's a very close relationship between sexual health and longevity.
Speaker AAnd that you know, like there's actually, there was actually a study in 20, 20, 20 in the Journal of Sexual Medicine that was like 15,000 men and women.
Speaker AAnd they found that people who had sex at least once a week had a, they had a 50% lower all cause mortality rate compared to people who were not having sex.
Speaker ASo they were half as likely to die.
Speaker AAnd it doesn't mean that sex makes you live longer, but it does mean that there's a close correlation between having, having an active, healthy sex life and being healthy in general, both from an emotional, mental, physical standpoint.
Speaker ASo essentially, sexual activity can sometimes be an indicator.
Speaker ALike if you're having sexual problems, it can be an indicator that something else is going on in your health.
Speaker BIt sounds like it really just also helps, like quality of life, you know, like your enjoyment and your pleasure and, you know, I feel like a lot of women, especially at this time, have just left, lost that mojo, you know, kind of like lost themselves a bit.
Speaker BYou know, they're kind of, maybe they're dealing with some aging parents, maybe they're dealing with kids going away and being empty nesters and reconnecting with their partners.
Speaker BI mean, is that like, what would you say to a woman like that who just feels lost, like she's lost her sexual mojo?
Speaker AI mean, I feel like we've all been there, right?
Speaker ALike, it is, it's, it's a hard time.
Speaker AIt's a, it's a tumultuous time, whatever that word is.
Speaker AIt's a, it is a hard time to be a woman.
Speaker ALike, and I think a lot, you know, a lot of us have had partners for 15, 20 plus years.
Speaker ASo there's also that part of it.
Speaker ALike maybe there's some boredom in there.
Speaker AWe have kids that are getting older and going to college.
Speaker ALike, that's stressful.
Speaker AWe have aging parents.
Speaker AThat's stressful.
Speaker AOur hormones are crazy.
Speaker AThat's stressful.
Speaker AOur bodies are changing.
Speaker ASo I think, you know, give yourself a little bit of grace.
Speaker ABut if you're interested in, in maintaining, you know, sexual vitality and, and sexual activity, just know that there are a lot of things that can be done both from a psychological, emotional, mental standpoint, but also from a physical standpoint.
Speaker BAnd I love this too of what you said about aging kind of being optional, you know.
Speaker BSo what do you think are some of the biggest needle movers to help women, especially in midlife and on a cellular level, you know, reach their full potential for longevity?
Speaker AI mean, there's so many, there's so many needle Movers, I think certainly hormones.
Speaker AI mean, I talk about hormones all the time and you know, I'm a big fan of estrogen and testosterone and progesterone.
Speaker AAnd I think all women should at least have that discussion with their doctors that, you know, about the possibility of taking hormones whether they choose to or not.
Speaker AThat's up to them.
Speaker ABut I think hormones are key.
Speaker ABut other things, like mitochondrial health is super important for overall health.
Speaker AAnd actually the, you know, the mitochondria are the little powerhouses of your cells, right?
Speaker AThey make your cellular energy.
Speaker AAnd starting about age 25 or 30, every lose about 1% of mitochondrial function.
Speaker AAnd mitochondrial function goes down significantly when we lose estrogen.
Speaker ASo estrogen and mitochondria are like BFFs.
Speaker AAnd so when you lose estrogen at late perimenopause menopause, mitochondrial health suffers significantly.
Speaker AAnd all of a sudden you're much more tired.
Speaker AYou can't get things done.
Speaker AYou're, you know, you're wired and tired maybe.
Speaker ABut so working on mitochondrial health specifically, I think is a, it's a key part of health that most doctors don't even talk about.
Speaker BSo how do we analyze that in ourselves?
Speaker BLike, how do we find out if our mitochondrial health is optimal?
Speaker AEven There aren't a lot of great tests.
Speaker AThere are a couple of advanced lab tests out there that will look, that can look at mitochondrial function if you have like a functional health doctor.
Speaker ABut, but there really aren't that many tests.
Speaker AYou kind of have to go by symptoms and also probably just know that if you are in midlife, you probably don't have peak mitochondrial health unless you're doing everything right.
Speaker ASo certainly healthy lifestyle, you know, getting enough sleep, getting, working on stress management, exercising, like high intensity interval training can be helpful.
Speaker AMaybe even a little bit of intermittent fasting to give mitochondria a break can be helpful.
Speaker AThere are, there's a whole number of supplements that can kind of support mitochondrial health as well, including things like ketones, like exogenous ketones that you can drink, which are great because it kind of, it's like an alternate fuel source for your body and gives your mitochondria a little break.
Speaker ASo there's a lot of different strategies that we can use, but you kind of have to work with someone who understands, you know, that this, what this is.
Speaker BAbsolutely.
Speaker BAnd I'm glad you brought up the hormones too, because I think that that is obviously such a hot button topic right now.
Speaker BYou know, recently it's the FDA approved, like vaginal estrogen and said it was of course safe and everything, which is a change from what was told to us, you know, 20 years ago.
Speaker BSo for the women though, I mean, I know there is a small population of women who actually can't take pregnancy hormones.
Speaker BWhat would you say to them?
Speaker BLike, is there, are there natural resources or supplements or things like that that they can take?
Speaker AI mean, I, I think that no.
Speaker AHormones are, are a piece of the puzzle.
Speaker AThey are not the entire puzzle.
Speaker AAnd certainly if you can't take hormones because you've had breast cancer, for instance, which is the most common reason that women can't take them, then you, you just want to understand what those hormones would be doing in your body.
Speaker AAnd, and then you can start to kind of replace that in terms of your lifestyle or your food or your supplements.
Speaker ASo for example, loss of estrogen at menopause is a major driver of bone loss and osteoporosis because estrogen, you know, keeps your bones healthy.
Speaker AAnd we know that.
Speaker ASo if, if you know this is come, this is coming and your bones are going to start becoming less healthy because you're losing estrogen, then you have to be very strategic about keeping your bones healthy with weight training, with, you know, heavy lifting, resistance training, with like jumping exercises.
Speaker ASo you're, you have some high impact on your joints with, you know, the appropriate nutrition with, with supplements like vitamin D and vitamin K and magnesium and some of these things and you know, sort of essentially taking bone health and like making it one of your like part time jobs because you don't have the help of estrogen, you have to do it yourself.
Speaker BAnd are you concerned at all about the heart too?
Speaker BLike with heart health and loss of it?
Speaker BIs that.
Speaker AAbsolutely, yeah, absolutely.
Speaker BWhat would you recommend for that?
Speaker AHeart attacks are the number one killer of women.
Speaker ASo one in every three women will die of a heart attack or a heart related illness.
Speaker ASo it is absolutely.
Speaker AWe know estrogen is very cardio protective.
Speaker ASo you know, again, like taking cardiac health very seriously, looking at your blood pressure, you know, in all of these things, traditional medicine has kind of a cutoff of what's considered too high or, you know, or abnormal.
Speaker ABut there's also like this whole range below that that's maybe not like too high, but it's still, still like not optimal.
Speaker ARight.
Speaker ASo understanding what is the optimal blood pressure, what is the optimal blood sugar?
Speaker ALike, maybe you aren't diabetic, but you also don't want to be pre diabetic.
Speaker AYou want to be like optimal, you want to be way down Here for blood sugar, Same thing for cholesterol.
Speaker AKeeping your cholesterol like be, you know, your cholesterol low, your, your ldl, C, your apob, but essentially like understanding what are the drivers of heart disease and then going like hog wild in terms of making sure that you don't have those things so that you don't develop heart disease.
Speaker BThat's such a great point.
Speaker BSo when I opened up my DMs, one of the questions that I asked was about three specific things.
Speaker BIt was about peptides, PRPs and exosomes.
Speaker BAnd I know you are on the forefront of all of those things.
Speaker BSo before we start diving into each one of those in five years, what do you think of those three, or maybe even all of them will be the most mainstream thing like the go to for women.
Speaker AI love that question.
Speaker AI don't think prp.
Speaker APRP has been around forever and I don't think it's going to be.
Speaker AThat's just essentially you take your blood, we spin it, we get your platelets and we put that back, you know, in some part of your body to help repair.
Speaker AIt's a great therapy.
Speaker AI just don't think that it is going to be the next generation thing.
Speaker ACertainly stem cell therapies include including exosomes.
Speaker AExosomes, if you don't know, essentially stem cells, the way that they communicate with each other and with other cells is they release these little bubbles of information that are called exosomes.
Speaker AAnd within those you have like growth factors and messenger RNA and cytokines and all these like things that tell other cells what to do.
Speaker AAnd so you could actually, we have products that we can, we could just use the exosomes or we can also use the entire stem cell, depending on what we're doing.
Speaker ABut they're both really great ways to help repair.
Speaker AAnd there's new, there's new versions of these stem cell therapies coming out all the time, like, that are more specific for, you know, like for instance, if we wanted to inject them into your scalp to regrow hair, there are new versions coming out that are specific for hair, hair regrowth versus or for, you know, repairing and whatever.
Speaker ASo we're getting better and better at that.
Speaker AAnd so I think in the future we'll have much, many more of these products that are approved and that can be used even by like your general doctor.
Speaker BOkay, are we ready to take the deep dive?
Speaker BHere we go.
Speaker BWhat is an exosome exactly?
Speaker BFor the women who maybe have never heard of this or maybe they, you know, you're starting to see it more in skin care, I'd say, you know, you see exosomes or you do it maybe after some plastic surgery or some treatments.
Speaker BBut for like, those women that are not so familiar with the exosomes, how can exosomes help them?
Speaker ASo exosomes, like I said, they're basically these messenger bubbles that come from stem cells.
Speaker ASo when we give, for instance, if I was to give you stem cells into your face, if I injected your face with stem cells, which is something I do, the way that those stem cells work is they release these exosomes and other growth factors, and then those things kind of float around and then they get captured by the cells in your face and those exosomes get internalized, and then those exosomes change.
Speaker AChange the way that your cell behaves.
Speaker ASo, for instance, if I want your fibroblast in your skin to make more collagen and elastin to give your face, you know, better health and structure, then theoretically we could give you exosomes directly.
Speaker AAnd that's like a, it's like a blueprint that's being transferred to the cell, but it doesn't have any DNA in it.
Speaker AIt's, it's got just growth factors.
Speaker ASo essentially it's a way to communicate that we want to increase healing, increase rejuvenation, regeneration.
Speaker ABut you're using your own body to do that.
Speaker BOkay, and for exosomes, that's primarily for skin, Correct?
Speaker BLike skin and face.
Speaker AAnd exosomes are not FDA approved for anything, but they can't, they're, they are allowed to be used topically.
Speaker ASo that's why we see them so much if, you know, like after micro needling of the face or after micro needling of the scalp.
Speaker ASo they're, they're, they are used other ways.
Speaker ACertainly they're around, but, but that they're approved mostly just for aesthetics.
Speaker BOkay, now peptides, this is like the hot, hot, hot topic right now.
Speaker BThey're so having a moment.
Speaker BIt's like, I feel like I look on social media and I see peptides here and peptides there.
Speaker BSo also for women who may not be so aware of what peptides are, can you just kind of go through what they're used for and how they really help with regenerative treatments and health?
Speaker ASo peptides are just short proteins.
Speaker ASo proteins are like these very long complex amino acid chains, right?
Speaker ABut peptides are very short amino acid chains.
Speaker AMaybe they're four or five or six amino acids long.
Speaker ASo they're very short.
Speaker AAnd so they each have, and they come from like you have them within your own body.
Speaker ASo essentially the ones that we use in practice are just taking what your body's already making and we're just, we're just taking that and we're multiplying it essentially.
Speaker ASo, so there's all different peptide.
Speaker AThey do different, many different things.
Speaker AFor example, one of the most common ones is BPC157.
Speaker AThat's the one that everyone hears about.
Speaker ALike, it's the, it's the most common one normally in your body.
Speaker AIt's found in your stomach juice, it's actually in your gastric juice.
Speaker ABut it does a lot for healing the gut, for instance.
Speaker AIt also does a lot for helping to repair and heal musculoskeletal pain.
Speaker AIf you had a, you know, rotator cuff injury or Achilles tendonitis or things like that, then that BPC157 potentially be helpful.
Speaker AThe thing about peptides that you should know, however, is that most of these are not regulated by the fda.
Speaker ALike, they're not, they're not, they, they haven't gone through the FDA process to become full drugs, except for a few, a few versions like the GLP1s, like, like semaglutide, tirzepatide.
Speaker AThose are peptides, but they've gone through the full FDA drug application process.
Speaker ARight.
Speaker ASo those are drugs, but there's a whole class of peptides that haven't gone through yet.
Speaker AYet.
Speaker AWho, so they're not as well studied.
Speaker AThey are, a lot of them are not even studied in humans.
Speaker ASo we do have to be careful and say, you know, these are still very much experimental, even though we think that they could help with a lot of things.
Speaker BAbsolutely.
Speaker BAnd for peptides, what is the best method of taking them?
Speaker BLike, is it the injections?
Speaker BIs it, you know, I've even seen like GLP gummies and powders and things like that.
Speaker BWhat do you, what do you think is the best way to take these things?
Speaker AI mean, most of them are going to be the best, best taken by injections, like little subcutaneous injections, like a little insulin needle, like in your stomach, for instance.
Speaker AThere are some peptides that are, that can be taken either like as a nasal spray or a sublingual like, like underneath the tongue or even a pill.
Speaker ASome of, some of them, like the BPC actually does survive through in the stomach.
Speaker AIt does survive the stomach acid because it comes from stomach acid.
Speaker ASo that one is one that's bioavailable orally but most of them are going to be better, have better bioavailability if they're injected.
Speaker BOkay.
Speaker BOne of the questions that I got also was about Tess Morlin and test more than they wanted to know.
Speaker BIs tesmoreland better than CJC and what your thoughts were on that?
Speaker ASo Tessamorelin and CJC 1295 are both examples of peptides that help to increase your own growth hormone production.
Speaker AAnd they are used.
Speaker ATesmorelin is actually FDA approved.
Speaker AIt is a, it is a drug.
Speaker ACJC 1295 is not that one is commonly used with something called ipamorelin.
Speaker ABut basically, long story short, I prefer Tess Marellin.
Speaker AIt is, it's better, but it's also a lot more expensive.
Speaker ASo it is, it's one of those things that you have to kind of decide the, that how much you can afford kind of thing.
Speaker BAnd they do, they both sort of target weight loss and muscle building and things like that.
Speaker AThey are.
Speaker ASo they increase your body's ability to make growth hormone.
Speaker ASo you're making it yourself.
Speaker AAnd so it works better.
Speaker AYou know, people who are generally a little bit younger, not, not in your 70s or 80s, but yeah, you're increasing growth hormone, which growth hormone is important for everything from muscle building to, yeah, potentially weight loss to, you know, your joint health to brain health.
Speaker AI mean, it really, it spans all the systems in the body.
Speaker ASometimes we'll use it, for instance, with people if we're using, if they're using GLP1 medications, they're using like Ozempic and they're losing weight.
Speaker ABut we want to make sure that they're also maintaining a little bit of muscle.
Speaker ASo sometimes we'll add like one of these growth hormone peptides to try to help them maintain muscle because they're, you know, as they're also lifting weights and doing all the lifestyle things because we don't want to, we don't want them to get skinny but not have muscle.
Speaker BGood point.
Speaker BAlso, we're hearing a lot about NAD and NAD plus injections.
Speaker BSo what are your thoughts on that?
Speaker BDo you think that that is an effective treatment to take?
Speaker AYou know, I've had, I've had a lot of back and forth on this.
Speaker AI actually, you know, I have a supplement company for women called Hotbox and we chose to put a precursor to nad and they're called nr, which is nicotinamide riboside.
Speaker AAnd the reason we chose that one is because it actually crosses the cell membrane and gets into the cell much easier than either NAD itself.
Speaker AWhich doesn't do that, or in a min, which is the other one.
Speaker ASo I prefer, I think that in our.
Speaker AJust taken as a daily supplement orally is.
Speaker AIs better than doing, you know, IV NAD or even NAD injections, because NAD is a.
Speaker AIt's a big, big molecule.
Speaker AIt doesn't actually.
Speaker AIt's not able to get into the cells, into the mitochondria like we wanted to as that big chunky molecule.
Speaker BOh, interesting.
Speaker BSo are we wasting our money if we're buying NAD supplements without the nr?
Speaker AIn the studies that have been done looking at NAD iv, for instance, what they found is the nad, it does eventually get broken down into components that can be transported into the cell and used.
Speaker ASo I, I don't.
Speaker AI wouldn't say necessarily you're wasting your money.
Speaker AHowever, instead of having to take something that gets broken down and transported, it's.
Speaker AWhy don't you just take the thing that's already broken down?
Speaker ALike, you're essentially like nr.
Speaker AYou're skipping the step of having to break something down.
Speaker AIt just goes straight into the cells.
Speaker AAnd you can take it in a daily supplement, like in Hotbox, and you get your levels up, they stay up, and you don't have to, you know, spend $1,000 on an IV.
Speaker BGood point.
Speaker BWe like that.
Speaker BAlso, needles, you know, I mean, who likes a needle?
Speaker AI don't like a needle.
Speaker BSame.
Speaker BSo who is a good candidate for peptides?
Speaker BIs there like a certain age bracket or maybe body composition?
Speaker BWhat are your thoughts on that?
Speaker BLike, how do you know if peptides.
Speaker BPeptides would be good for you or not good for you?
Speaker AThere are like.
Speaker AI mean, there are hundreds of peptides, probably about 20, 25, that are commonly used.
Speaker ABut I mean, there, there's, there's one.
Speaker AThere's peptides for sleep.
Speaker AThere's peptides for sexual health.
Speaker AThere's peptides for healing musculoskeletal injuries.
Speaker AThere's peptides for skin, for hair.
Speaker ALike, there's a, you know, it's for immune function and helping to fight illnesses.
Speaker ASo there's, there's peptides that for all different things.
Speaker ASo I think, you know, most people are candidates.
Speaker AWe don't tend to give peptides to people.
Speaker ACertainly if you're pregnant, we don't give you anything experimental because it just hasn't been studied.
Speaker AIf you have active cancer, we're not messing with your.
Speaker AWe're not giving you anything experimental.
Speaker ASo there are people who we don't get, you know, we just say, this is not a good choice for you.
Speaker ABut Other than that it, most of them we think are pretty safe because they're all, they all come from your body.
Speaker ABut they also, you know, you do want to have a medical practitioner who knows about peptides.
Speaker ALike I do not recommend just going onto the Internet and buying research peptides and you know, injecting them into your body.
Speaker AI think that's probably not a good idea.
Speaker BThat's a good point.
Speaker BIs there like an age where it sort of tops off, like it stops maybe at a certain, maybe 70 or something?
Speaker BOr can you take it throughout your whole life?
Speaker AI mean, as far as we know you can take it throughout your life.
Speaker AI haven't, you know, we, I haven't had any people in our, in their like 80s or so that are on a lot of peptides most of the time.
Speaker AThat's just not something that they're interested in doing.
Speaker ABut, but you know, we, as far as we know that they can be used forever.
Speaker AIt depends on again what the peptide is trying to do in your body and whether or not it's going to make sense with your body.
Speaker BAbsolutely.
Speaker BAnd you know, we were talking a little bit earlier about PRP and I think sometimes when people think prp they're thinking the vampire facial for example, you know, and so that's kind of what, where the knowledge stops.
Speaker BBut PRP is actually used for a lot more than just something like that.
Speaker BSo are you a fan of PRP and what would you recommend PRP for in midlife women?
Speaker AYeah, I mean PRP is when you think about the like regenerative biologic.
Speaker ASo things that are biologic that we inject.
Speaker AYou know, PRP is kind of the, one of the, like the most used one.
Speaker AIt's been around for decades.
Speaker AIt's super safe.
Speaker AIt just comes from your own blood and it's just platelets from your own blood that we re inject.
Speaker ASo PRP is, is great, but you do generally need a few treatments.
Speaker ASo like if you're doing it for your scalp, you need at least three treatments.
Speaker AIf you're doing it for your face, you know, you generally want to do about two or three treatments.
Speaker ASame thing for your knee.
Speaker ASo it's like, it's a good therapy.
Speaker AIt's very safe.
Speaker AIt's not as strong as like the next level up which would be probably stem cells or exosomes or some of these other kind of higher level regenerative therapies where they're going to be more expensive, but they also generally have better outcomes with a single treatment versus prp.
Speaker ABut they're all kind of the same.
Speaker AThey all work in a similar way.
Speaker BSo PRP is relatively safe for most people?
Speaker AYeah.
Speaker AOh, yeah.
Speaker APRP is extremely safe.
Speaker AThe only thing that, the only potentially dangerous part are the injection.
Speaker ASo, you know, you could get a, you could get a joint injection, infection in your knee if someone used a dirty needle or if you had, you know, like, like there's some technique, things like that.
Speaker ABut the PRP itself is extremely safe.
Speaker BYou know, hormone optimization is so important in your practice and what you talk about.
Speaker BSo what are the signs that women should look for to see if their hormones are off?
Speaker BYou know, and how should they be, like, you know, reevaluating their own lives to make sure that hormone optimization is there?
Speaker AWell, I think, I think all women should be getting, you know, basic hormone testing at least once a year.
Speaker AAnd that's like thyroid.
Speaker AThat's, you know, if you're over 35 or so, probably testosterone, you know, cortisol, if there's any concerns, like there's some hormones like insulin, things like that that you should be getting every year.
Speaker AAnd then as you get into perimenopause, which is, you know, can happen in the five to 10 years before menopause, so often starts as early as 35 or so, then having a, a physician who understands the symptoms to look for, because there's, you know, 30 plus symptoms in perimenopause that are.
Speaker AThat could be still stem from progesterone going down and testosterone going down and estrogen going down, and then eventually menopause.
Speaker AI don't, you know, you don't have to necessarily check labs like estrogen and progesterone to know that they're low.
Speaker ABut I do, I do recommend checking them at some point, especially if you're going to start therapy.
Speaker BYou know, I think it's interesting, too, a lot of women, when they go to their doctors and they say, you know, I feel off or, you know, I feel like my levels aren't quite right.
Speaker BA lot of them are gaslit by their doctors and, and said, you know, what if you're still having your period, you're fine.
Speaker BYou know, come back and talk to me when you miss a year's worth of a period.
Speaker BAnd so I think a lot of women are, you know, unsure what to do.
Speaker BSo what advice would you give women in sort of that situation that feel like they're being gaslit by their doctor?
Speaker AYeah, I mean, unfortunately, doctors just don't receive training or, you know, very much training at all in any of this stuff, even the gynecologist, even the endocrinologists, like, these are great doctors and they know a lot, but these, the training on how to care for a woman in perimenopause and menopause and how to use and how to optimize hormones, you know, across all ages is really not taught.
Speaker AAnd I think that that's it.
Speaker AIt's really a matter of we need to give more education for doctors.
Speaker ALike, I'm working on a course right now for doctors for that same reason.
Speaker ABut, you know, I, I guess you just kind of do keep asking.
Speaker AAnd also, if your doctor is not familiar with how to treat this or, you know, understand how to even diagnose problems, you may have to find a new doctor.
Speaker ALike, that's.
Speaker AUnfortunately, your doctor may not be able to be educated quickly enough for, for your needs.
Speaker BIs there an age that is too young to start getting a baseline test for your hormones or is that some, like, somebody, women in their twenties should be doing?
Speaker AWell, it depends on what hormones you're talking about.
Speaker AIf you're talking about like things like thyroid, your insulin, you know, these hormones you should be checking every year as, like starting as an adult, like every year you'd have those checked.
Speaker AIf you're talking about things like estrogen and progesterone, then it is true that if you're having really normal cycles and aren't having any problems, you probably don't need to check those labs.
Speaker ALike, if you're 25, 30 years old and you, you know, don't have any cycle problems or they're, you know, everything is pretty fine, then your, your hormones are probably fine.
Speaker AIf, however, you're, you are 25 or 30 years old and you have irregular cycles or no cycles, or, or, you know, you're skipping several months at a time, or you're having like, severe bleeding or pain or all those kinds of symptoms, then absolutely you should be, you should get your estrogen, your progesterone, your testosterone, like your fsh, your lh.
Speaker AAll these hormones should be checked.
Speaker AAnd there is a right time to check the hormones.
Speaker AThere's a right way to look at, like, it's not something as easy as just like, what's the normal, like, what's the optimal level?
Speaker ABecause it's, you know, they're changing every day right during your cycle.
Speaker ASo you need to have a doctor who understands what, when to check the hormones.
Speaker AWhat are the, what are the optimal levels, what's too high, what's too low, what else to look out for.
Speaker AIt's it's complicated.
Speaker ARight.
Speaker BAnd it's holistic.
Speaker ARight.
Speaker BIt's like the whole body because of something you have inflammation maybe that ties.
Speaker BRight.
Speaker BThere's just so many moving parts.
Speaker ARight.
Speaker A100%.
Speaker ALike, you know, you could be having, you know, irregular periods because you are stressed out and you're, and you're not making, you know, you're not ovulating properly because you're stressed.
Speaker AAnd then your progesterone is not high enough.
Speaker AAnd so now you're having insomnia and we worsening stress.
Speaker ALike, it is a, it is a complex system.
Speaker AAnd so you do have to think of it, like you said, like holistically, not just, you know, how are your ovaries doing?
Speaker BAbsolutely.
Speaker BSo let's talk skin because, you know, we like to look good.
Speaker BLet's, let's be honest, you know, so I love that you are, you know, preventative in that way, especially with the regenerative health.
Speaker BAnd so we're not, we want to talk about interventions that will make sense and help us.
Speaker BSo what are the three things that you think women over 40 should stop wasting their time on as it relates to, you know, having great skin, looking good, feeling youthful, all those things.
Speaker AOoh, that's a hard one.
Speaker AYou know, I don't, I think that most of the.
Speaker AI'm, I'm a fan of many of almost all of the different cosmetic interventions.
Speaker AWhether it's something like microneedling or an apply, you know, applying PRP afterwards or, or, or just doing good skincare with, with sunblock and retinoids, which are fabulous.
Speaker AI do, you know, there are some of the, some of the, like the deeper treatments.
Speaker AI'm not as big a fan.
Speaker ALike, I don't think that the, the radio frequency microneedling treatments are right for everyone.
Speaker AThat's like the Morpheus and the things where it has the needles that heat up inside your skin, those were all the rage for a while.
Speaker ABut then people started noticing that that was actually causing a lot of volume loss, like fat loss in the face, which is making, which makes you look older.
Speaker AAnd so, you know, I think that there's a right way to do it, but I also think that there's a wrong way to do it.
Speaker ASo, you know, there's all these things kind of come in and out of vogue, but any, you know, all of these treatments, these lasers, radio frequency treatments, you know, like ultrasound based heating treatments, like ultrapy, all of them have a place again, but with someone who knows how to use these tools.
Speaker BSo, okay, so you're not a big fan of Morpheus 8?
Speaker AYou know, I've done a lot of it myself, but I think, I do think it's, I do think it could be helpful at the, like, the, like, the less deep needle, you know, levels.
Speaker ABut I don't think it's a good idea to go deep in the skin.
Speaker AIf you have someone who is getting older, you don't want to lose fat in the face.
Speaker BOkay.
Speaker BSo that maybe you want to be very careful when you, when you do that one.
Speaker BHow about like Botox fillers?
Speaker AThat whole realm, you know, I actually think all of those things are great.
Speaker AIt, again, if, if done properly.
Speaker AI am not worried about Botox.
Speaker AI know that a lot of people have concerns that it's dangerous to your brain or things like that.
Speaker ABut I mean, it's been, you know, this is one of the most used, utilized and studied, you know, treatments that we've had for decades now.
Speaker ASo I don't think, I think it's fine.
Speaker AI certainly don't think you have to do it.
Speaker AI don't think we should, any of us should feel pressure to do anything.
Speaker ABut I think that Botox and these, these toxin treatments are appropriate in, in, you know, small doses.
Speaker AI think fillers could be great fillers and sculpture.
Speaker ABut again, you have to know what you want your doctor to know what they're doing to be.
Speaker AYeah, because there are potential side effects that could be really dangerous if you get in the wrong hands.
Speaker BDo you think we need to be worried about the migration of, you know, we've heard like sometimes it can migrate in your face and things like that.
Speaker BIs that something to worry about?
Speaker AI, I haven't seen a lot of migration.
Speaker AI, I do think that it could, that these fillers do stick around longer than we thought when we used to think that they were just stick around for six months to a year.
Speaker ABut, and I don't do, you know, I don't do facial surgery.
Speaker ASo I, but I just know that a lot of my surgery friends, when they're going in and doing facelifts or, you know, things like that later, they're finding filler in there that was there from, you know, five years ago.
Speaker AAnd so I do think it's.
Speaker AThey're lasting a lot longer than we think and that, you know, and certainly at some point it doesn't make sense just to keep adding more and more and more filler.
Speaker AYou know, at some point, if you want that look, you may just need to get a facelift.
Speaker BYeah, exactly, exactly.
Speaker BJust go for the big one.
Speaker AYeah.
Speaker AAnd I have a Had.
Speaker AYou know, I haven't had a facelift, but I've done.
Speaker AI've done filler.
Speaker AI've done sculpture.
Speaker AI've done all the different.
Speaker AI did many lasers.
Speaker AI've done talk, you know, toxic.
Speaker AI did.
Speaker AI've done all of it on myself.
Speaker BSo for you, is there.
Speaker BIs sculpture sort of the filler kind of thing that you liked the most?
Speaker AI do like sculpture.
Speaker ASculptra is.
Speaker ASculptura is not.
Speaker AYou know, you're not filler.
Speaker AYou're looking at, like, one area, and you're kind of trying to, you know, get that one area to be filled.
Speaker ASculpture is more like you're looking at the whole face, and you're doing little bits here and there.
Speaker ASo it's.
Speaker AIt's.
Speaker AThey're different in how they work.
Speaker AAnd sculpture is kind of getting your own body to create the.
Speaker AThe collagen also.
Speaker ASo they both have their place.
Speaker AThere's not.
Speaker AThe thing is, people always ask me, like, what's the one thing I should do?
Speaker AThere is no one thing.
Speaker ALike, the one thing is.
Speaker AThe one thing is sunblock, probably if there's a one thing, and then maybe retinoids second.
Speaker ABut there after that, like, it really depends on how old you are, Your skin quality, your facial structure, your budget, you know, your comfort level with.
Speaker AWith trying new things.
Speaker AIt's.
Speaker AThere's so many variables.
Speaker BSo many.
Speaker BDo we need to be worried that any of these treatments will affect our hormone health?
Speaker ANo.
Speaker ANo, not that I know of.
Speaker BOkay, so we're pretty safe on that end.
Speaker BYou know, I loved.
Speaker BI was watching one of your videos last week about alcohol, you know, because that is something that we all feel nowadays.
Speaker BI feel like, you know, whatever, going out, talking to the friends, doing, like, a girls night.
Speaker BYou have a couple glasses of.
Speaker BOf wine, and the next day you feel like you've been hit by a truck.
Speaker BI mean, it's just.
Speaker AYeah.
Speaker BRemember, like, back in the day, in your 20s, you'd have, like, three or four glasses of wine, and you were fine the next day.
Speaker BNow it's a different story.
Speaker BSo why is this happening?
Speaker BIs it just like that?
Speaker BWe just basically can't process it like we did before?
Speaker BLike, take it.
Speaker BTell me, like, start to finish.
Speaker BWhy is this happening?
Speaker AThere's a.
Speaker AThere's a few reasons.
Speaker AOne is, yeah, you can't process it the way you did.
Speaker AWe.
Speaker AWe.
Speaker AThe.
Speaker AThe alcohol dehydrogenase enzyme in your liver that metabolizes alcohol starts to slow down as you get older.
Speaker AAnd so your liver is literally able to process alcohol much slower.
Speaker ASo you're getting it staying in your body longer.
Speaker AAnother thing that happens is as you get older, you're losing muscle because that happens with age.
Speaker AAnd so, and muscle carries a lot of water.
Speaker ASo when you lose muscle, you actually start to become more dehydrated and you have a lower volume of water in your body.
Speaker AEstrogen also keeps you hydrated, so if you, you lose that, that's also making it worse.
Speaker ASo you become more dehydrated and then you drink alcohol.
Speaker AAnd then so it's like essentially it's more concentrated in your bloodstream because your bloodstream, you have less blood, less hydration in your blood.
Speaker ASo that's happening.
Speaker AAnd then there's also a lot of things in your brain.
Speaker AThe way that alcohol affects your, your, your neurotransmitters, your dopamine, things like that changes with age also, especially in midlife, and that's also makes it harder.
Speaker AAnd so it just becomes a lot worse for us.
Speaker AIt's true.
Speaker BYou just feel terrible the next day, you know, and I feel like a lot of women are really looking, looking at that and saying, you know, I want to cut back on alcohol or maybe only drink once a week as opposed to like two or three times a week.
Speaker BYou know, it's kind of implementing these lifestyle changes.
Speaker BRight?
Speaker AYeah, I think, I mean, a lot of women in midlife just decide to stop drinking.
Speaker AIt's just not worth, you know, it's not worth it anymore because our, you know, our sleep is already disrupted.
Speaker ALike we're already waking up with potentially hot flashes or nights was they're just waking up and can't go to sleep at 3am and then if you add alcohol to that, that's obviously going to make that worse.
Speaker AAnd so a lot of us are just like, you know, that's, that's not for me.
Speaker AI know I still drink a little bit here and there socially, but I have, I definitely have cut back.
Speaker AI don't, I don't drink every day by any means.
Speaker AAnd when I do, it's always one drink.
Speaker ABecause if I do more than one, I know it's not going to go well for me.
Speaker BRight, right.
Speaker BWhy is it that 3am that's the time every time I had wine, I know 3am Wake up.
Speaker AWhy?
Speaker AI don't, I don't know why exactly.
Speaker AYou know, alcohol is a depressant.
Speaker ASo it actually, it does, it makes you kind of, it makes you sleep, but it also does interrupt your REM sleep.
Speaker ABut I don't know why it is 3am for me as well.
Speaker BIt's true.
Speaker BIt's always that time.
Speaker BAre there any things that we can take the next day to help us feel better if we do indulge a little too much?
Speaker AI mean, there are a lot of products out there that are like, you know, the hangover kind of pill packs and, you know, IVs and things like that.
Speaker AI honestly, I don't know if they work or not.
Speaker AThere are a lot of them.
Speaker ATarget liver health and trying to get your liver to, you know, work faster.
Speaker AI. I haven't seen if there.
Speaker AIf those things really work.
Speaker AProbably just hydrate, make sure that you're.
Speaker AThat you're getting some good food in your body and maybe get some sunlight.
Speaker ALike that's what I recommend.
Speaker BYeah, it sounds like a good play.
Speaker BMaybe head to the beach and, you know, have some water, cool water on your skin.
Speaker BYou know, you see both men and women in your practice.
Speaker BSo what are the things that you think that women over 40 are doing better than men as it relates to taking care of themselves and helping, you know, with their health?
Speaker AThat's a great question.
Speaker AYou know, I do.
Speaker AI think that women are becoming, especially now, are becoming more knowledgeable about perimenopause and menopause and these hormonal changes.
Speaker ASo one thing, a trend I've seen now is women just asking a lot more detailed questions about their health than men.
Speaker ALike, you know, men, a lot of them know about testosterone, but they don't necessarily.
Speaker AThey haven't been, you know, inundated with all this information that we're.
Speaker AWe're now seeing on social media for women.
Speaker ASo I think a lot of them just don't understand other things they should be asking about, you know, insulin sensitivity or thyroid function or, you know, like muscle mass and visceral fat or things like that.
Speaker ABut I think that I feel like women are becoming more educated because of the great people that are out there, you know, the doctors and the influencers and people who are talking about this so much now.
Speaker BAbsolutely.
Speaker BThat's something we really want to do here on the show is like, you got knowledge is power.
Speaker BLike, women should know these things, and they should be armed with, you know, all of this knowledge when they're going into their doctors or when they're even going out with their girlfriends.
Speaker BYou know, it's such a great time to talk.
Speaker AYeah, absolutely.
Speaker AAnd I think that women, women, you know, we all seeking answers like, we're a lot more complicated than Men, for sure.
Speaker AYou know, our hormones can go crazy in a lot of different ways, whereas men's usually.
Speaker AIt's just like a couple of ways, but.
Speaker ABut luckily, we also are more.
Speaker AYou know, we're.
Speaker AWe all.
Speaker AWe are.
Speaker AWe tend to talk more with our friends and to discuss.
Speaker AAnd we have the social component that I think is a little bit different than a lot of men do.
Speaker BThe men also suffer from, like, hormone drops in their midlife.
Speaker BDo they kind of go through.
Speaker AReally, they do.
Speaker AWell, you know, but in both men and women, testosterone starts going down starting at about age 25 to 30.
Speaker ABut it's like the slow, gradual descent.
Speaker ASo testosterone in men and women is.
Speaker AIs very different than estrogen and progesterone, which at menopause, you know, kind of falls off a cliff.
Speaker ALike, you go from like, it's fine, it's fine, it's fine to oh, my gosh, I'm out.
Speaker ATestosterone is a much slower decline.
Speaker ABut that.
Speaker ABut it happens in both men and women.
Speaker ASo men often about age 40, start feeling effects that are related to low testosterone.
Speaker ANot all men, but.
Speaker ABut some men.
Speaker ASo that's.
Speaker AThat's.
Speaker AIt's a common.
Speaker AIt's common for men in that age to come in and say, I just don't feel like myself these days.
Speaker BInteresting.
Speaker BUm, so how do we, you know, for.
Speaker BFor those of us that have partners who are men and going through midlife as well, like, what are the things that we can do to kind of help them?
Speaker BBecause, you know, men tend to be more closed.
Speaker BThey don't want to talk to about it.
Speaker BYou know, it's almost like I have to force my husband to go to the doctor, you know, so how can we support them during this time?
Speaker AWell, I mean, I would recommend getting your testosterone check.
Speaker AThat's easy enough to do.
Speaker AGet a total and a free testosterone.
Speaker AThere's a couple of other lab tests that we do at the same time that checks your pituitary gland function and things like that.
Speaker ABut, you know, get some lab tests done.
Speaker ABut the good thing about testosterone, this is different than with women.
Speaker AThere are a number of lifestyle changes that you can make to improve testosterone in men.
Speaker ASo, like lifting, lifting heavy weights, you know, getting exercise, losing belly fat, reducing stress, making sure you have enough, like, of some of the micronutrients, like, like selenium and zinc and vitamin D and things like that.
Speaker ABut like, so lifestyle changes actually can make a difference in men, especially younger men, in helping their body to make more testosterone.
Speaker BSo what do you think about this whole thought too about microdosing GLPs.
Speaker BHave you heard that?
Speaker BLike, I've seen it on social media where women are like, I'm just microdosing just because, you know, I'm in midlife and I feel like it's helping me.
Speaker BIs it helpful to do something like that or what do you think about that?
Speaker AYou know, I think that we need to learn more about microdosing.
Speaker AAnd you're certainly, you know, it's basically just any dosing that's outside of the normal parameters.
Speaker AYou know, it's lower than the normal FDA approved versions.
Speaker ABut I do think that these medications are, are fabulous and that there are a lot of indications for these medications outside of just weight loss that we're learning about every single day.
Speaker ASo I do, I have a lot of, I have a lot of patients who are taking small doses, these micro doses to try to help with things like inflammation or arthritis pain or, or polycystic ovarian syndrome or mast cell dysfunction or autoimmune diseases.
Speaker AAll these things that are, that are these, these medications, Ozempic, et cetera, are helpful at, but we don't have the data to say what the dose is yet or, you know, exactly how helpful they are at those baby doses.
Speaker BWhat is the one thing that you wish all midlife women knew about their health?
Speaker AI think the most important thing for women is to know that, that, that you have a lot of control of your health, but also you don't have all the control and you oftentimes need to get a kind of a co pilot, you know, medical provider who can help you with the pieces that you can't control.
Speaker ASo a healthy lifestyle is absolutely important.
Speaker AIt goes a long way to staying healthy, feeling good.
Speaker ABut it is not necessarily going to mean that you don't have perimenopausal symptoms or menopausal symptoms.
Speaker AYou know, it doesn't, it does not go all the way.
Speaker ASo yes, you have a lot of control, but also find that person that can help you if you need it.
Speaker BAnd what about the women who have had hysterectomies?
Speaker BAre they still going to, you know, have menopausal symptoms and the hot flashes and the brain fog and all that kind of stuff?
Speaker AOh, yes, they, when you have a surgical hysterectomy, you have your ovaries taken out.
Speaker AWith ovaries taken out, you essentially go, you go through entire perimenopause in the course of like 24 hours.
Speaker ASo essentially you go from normal production to no hormone production or very minimal.
Speaker AAnd so the symptoms could be very severe.
Speaker AAnd you know, unfortunately a lot of doctors, at least in the kind of old school doctors, weren't even replacing those hormones.
Speaker ALike even in fair, you know, I've seen, I have several, I've had young women who messaged me and said, you know, I had a hysterectomy with my ovaries taken out at age 30 and no one told me that I should be on hormones.
Speaker AAnd like there.
Speaker AThat's, it's, it's crazy.
Speaker AIt's absolutely crazy.
Speaker BThat's insane.
Speaker BThat is crazy.
Speaker BAnd what are like the three supplements that you think that every woman should have in her medicine cabinet no matter what?
Speaker AI love creatine, I love vitamin D3 with K2.
Speaker AI consider that to be just one thing, but it's actually two ingredients and probably magnesium is the third thing I like.
Speaker BOkay, yes.
Speaker BMagnesium is something we really lack, right?
Speaker AYeah, a lot of people lack it and it's, there's multiple different types of magnesium.
Speaker AMy favorite is magnesium glycinate because it's like, it's just easy, easily digested, it's great for sleep, it's great for kind of calming you.
Speaker ABut there's many types of magnesium.
Speaker ABut almost, almost, you know, a lot of people are deficient within magnesium.
Speaker BWhen we take vitamin.
Speaker BCuz you said D&K2, should we also be taking vitamin A and vitamin E with it?
Speaker BSo it's like a, like the four of them together or do we just need the D and the K2 together?
Speaker AYou don't necessarily.
Speaker AI mean, yeah, those are all the fat soluble vitamins but, and you certainly can take them together.
Speaker AMost of the formulations are going to be vitamin D3 and K2 together.
Speaker AAnd then you may have the other vitamins in like a multivitamin or something.
Speaker AYou know, I don't think the problem, the thing with vitamin D is we don't tend to get enough of it in our diets.
Speaker AAnd unless you're out in the sun, you know, at least 10, 15, 20 minutes a day, day, you don't get it from the sun either.
Speaker ASo women are like oftentimes deficient in vitamin D for that reason.
Speaker AWe're inside too much, we're on our computers too much.
Speaker ASo you know, a lot of the vitamins you can get in your food, if you have a healthy diet, you don't need to necessarily take a multivitamin.
Speaker AAlthough obviously our diets are a little bit different than they used to be.
Speaker AAnd the food sources aren't quite as quality as they used to be.
Speaker BAbsolutely.
Speaker BAnd oh, should we be eating all organic?
Speaker AThat's an interesting question.
Speaker AI think that the jury is still out and I'm sure that people in the wellness world would want to hang me for this, but I think that there are certainly foods that are going to be better organic.
Speaker AAll the dirty dozen foods, the ones that are on the list that have the thin skin, like apples and things that have a thick skin, organic is probably better.
Speaker ABut the thing is though, organic foods, oftentimes they're using, whether it's pesticides or versions of pesticides that are, because they still have to keep the bugs away.
Speaker AAnd so they're sometimes using less regulated pesticides or alternatives than, you know, this sort of other, other crop, you know, manufacturers.
Speaker AAnd so I don't necessarily think that organic is always healthier, although certainly in some cases it probably is.
Speaker BAnd with the meats and everything, do you think it's best to go organic?
Speaker AYou know, with meats, I recommend if you can afford it to do like, you know, the grass fed or pasture raised and free range, you know, obviously the sustainably raised is, agriculture is going to be better for the, for the environment and probably healthier as well.
Speaker AUnfortunately, those also cost quite a bit more.
Speaker ASo you kind of have to balance like what can your budget afford with, you know, what's the healthiest.
Speaker BAbsolutely.
Speaker BSo what advice would you give your 25 year old self?
Speaker AOh, that's a great question.
Speaker AYou know, I, I think that I would just, I would tell myself just to, to hang on and it's going to get, it's just going to get super fun.
Speaker ALike I feel like I'm having such a good time.
Speaker AI'm 49.
Speaker AYou know, certainly there's hard days, but I also, I, I love, I love the space of life.
Speaker AI think it's, it's, it's as challenging as it is.
Speaker AI also feel like it, it's very empowering and I, I love, you know, the person that, that I am trying to become.
Speaker AI don't necessarily love who I am all the time, but I like this journey of a lot.
Speaker AYeah.
Speaker BWhat is the best part of midlife for you right now?
Speaker AYou know, I just, I feel like I'm just stretching myself a lot.
Speaker ALike I have, you know, I have several companies.
Speaker AI do, you know, I do a lot of social media, I do a lot of teaching.
Speaker AI'm getting to do, I'm getting to do all the things that I like to do.
Speaker ALike I used to be an ER doctor, which was fun for a little While.
Speaker ABut then I left and I didn't.
Speaker AI had no idea what I was going to do with.
Speaker AFor my profession, for my job.
Speaker AI had no income, you know, for a while.
Speaker AAnd so it's, it's just fun for me.
Speaker AI get to.
Speaker AI'm.
Speaker AI'm getting to create exactly what I want to, you know, even though it's a lot of work, I just love this field of medicine so much.
Speaker BIt is, it's an exciting field.
Speaker BThere's so many developments and changes and things like that.
Speaker BHow are you living iconically right now?
Speaker AIconically?
Speaker AOh, my goodness.
Speaker AI don't know.
Speaker AI don't know if I'm living iconically.
Speaker AYou are?
Speaker AI don't know if I am.
Speaker AI. I don't know if I am.
Speaker ABut I do try.
Speaker AI try to.
Speaker AI try to have fun.
Speaker AI try to.
Speaker AOne of my biggest beliefs is like, you know, in terms of whether that's the way we live and where we educate other people is to bring a playfulness and a fun, like a funness to it.
Speaker AI feel like that's lacking in a lot of, in health care and wellness.
Speaker ALike the play.
Speaker AThe play part of it I think is so important.
Speaker ASo I think one of, one of my.
Speaker AI don't know if it's a gift or a Fitch is something that I've kind of forced on the world is that I try to bring that fun to my teachings, to the things I'm doing to, you know, to my teams.
Speaker ASo hopefully that's, that's something.
Speaker BIt is.
Speaker BIt makes it more digestible for people too.
Speaker BYou know, they're.
Speaker BThey're having fun with it, like you're saying and smiling and having a good time.
Speaker BSo on the iconic midlife, we like to wrap up the show with a game.
Speaker BAre you down?
Speaker AOh, okay.
Speaker AI'm ready.
Speaker BAll right, so it's a rapid fire game and it's going to be called Science or Science Snake Oil.
Speaker BSo basically I'll kind of name a hot button topic or, or a buzzword and you let me know what you think.
Speaker BIf it's, you know, grounded in research and worth, like doing or snake oil meaning, like we should just pass.
Speaker AOkay, I'm ready.
Speaker BPerfect.
Speaker BOkay.
Speaker BCollagen powders and drinks.
Speaker ASnake oil for skin.
Speaker AScience for bones and joints.
Speaker AReally?
Speaker BSo there is a difference.
Speaker AYeah.
Speaker AI just wrote a sub stack on this and went into all the studies.
Speaker AThere's so, so yeah, check out my sub stack.
Speaker AAnd it, it's.
Speaker AI went into it pretty deep.
Speaker BOkay.
Speaker BGood to know.
Speaker BOzone therapy for anything I, I would.
Speaker ASay to be determined.
Speaker AI mean, I, I think that there is some good science out there.
Speaker AI'm not sure we know quite how to harness it best, but I think it's.
Speaker AI do think it's.
Speaker AIt's a.
Speaker AIt's a maybe.
Speaker BOkay, a maybe.
Speaker BNAD plus IV drips.
Speaker AI don't like them as much as I like the pills.
Speaker AI like the NR pills better than NAD iv.
Speaker AOh, really?
Speaker BSo you think it's.
Speaker BThe pills are more effective or.
Speaker AI just think that it's a less expensive, easier way to get the NAD that you're wanting to get.
Speaker BOkay, good to know.
Speaker BRed light masks for anti aging science.
Speaker AAs long as it is a good quality mask.
Speaker BOkay.
Speaker BSemi glutide for biohacking aging and not weight loss science.
Speaker BOkay.
Speaker BHormone pellets for everyone.
Speaker AIt's snake oil for everyone.
Speaker AHowever, I don't think that they're always bad.
Speaker AI think that I, you know, pellets can.
Speaker AThey do have uses.
Speaker AThere are people who do great on them.
Speaker AI think the idea that nobody should have pellets is silly.
Speaker BOkay.
Speaker BOr do you prefer various methods of, like, the hormone delivery system?
Speaker BIs there one that you think is more universal, maybe for people, or is it just totally individual?
Speaker AIt depends on the hormones.
Speaker ALike, you know, for, for estrogen, I like transdermal.
Speaker AI also like oral.
Speaker AFor testosterone, I like injections or trans or transdermal progesterone or like oral or vaginal.
Speaker BOh, okay, good to know.
Speaker BSuppository, vitamins and vaginal detox.
Speaker APearls.
Speaker ASnake oil.
Speaker BOh, yeah.
Speaker BWhat do you think about the.
Speaker BThat whole.
Speaker AThe egg.
Speaker BRight?
Speaker BThere's like the, the egg that you.
Speaker AThe jade.
Speaker BThe jade egg, that's right.
Speaker AI mean, it's just silly.
Speaker AIt's.
Speaker AIt's.
Speaker AIt's just a marketing propaganda.
Speaker BOkay, good to know.
Speaker BIV glutathione for skin health.
Speaker AI don't know specifically for skin.
Speaker AI do think that glutathione is important.
Speaker AI don't.
Speaker AAnd again, I haven't.
Speaker AI haven't seen.
Speaker BSeen.
Speaker AI guess it's kind of middle.
Speaker AI haven't seen a lot of studies on IV glutathione, but we do know it's important in our bodies for many parts of detoxification and things like that.
Speaker ASo I'm not sure.
Speaker BOkay.
Speaker BVaginal steaming snake oil.
Speaker AGood.
Speaker BOne less thing to have to worry about.
Speaker BOkay.
Speaker BCold plunges for hormone health.
Speaker AIt's.
Speaker AI would say snake oil for hormones, but I do like.
Speaker AI do like cold plunges for recovery from workouts, reducing Muscle soreness and for stress relief and kind of neurologic stress adaptation.
Speaker BOkay, so you do like it for women because I've also kind of heard maybe it's more effective for men just because of their, like their makeup.
Speaker BWhat do you think about that?
Speaker AYeah, yeah, I just actually am working on a sub psych on this too that we don't actually.
Speaker ASo most of the studies have been done in men.
Speaker AWe have a lot more data on men than we do women, but we don't really have good evidence that they're problematic for women.
Speaker AIn both men and women, the cold plunges should be a little warmer than we thought.
Speaker AThey should be between 50 and 60 degrees and you should be going between around 10 minutes.
Speaker ASo it's a little warmer and a little longer than we thought is probably ideal for both men and women.
Speaker ABut I do think that, that women can, can certainly do cold plunges.
Speaker AJust understanding.
Speaker AListen to your body.
Speaker ADa da, da da.
Speaker BOkay, and should we be doing it at a certain frequency or like once a week or more?
Speaker AIt's, it's usually about two to three days a week is probably about right.
Speaker AYou don't want to do it necessarily every day because you, you get habituated to it.
Speaker ABut if you, you know, two or three times a week, you want to do it ideally within an hour of like a aerobic exercise.
Speaker ALike if you go out and run a long time, you want to do that within an hour.
Speaker AYou don't want to do it after strength training exercises because that will actually blunt muscle growth.
Speaker ASo you want to wait at least four hours after your weight training exercise to do any kind of cold water.
Speaker BSo if we do the, the heavy strength training, should we be going in like an infrared sauna after that?
Speaker BLike it's like the opposite.
Speaker BOr just.
Speaker AYou can't.
Speaker AYeah, you, you certainly can.
Speaker AYou can do sauna.
Speaker ASauna is fine anytime.
Speaker ABut cold.
Speaker AThe cold water, you know, if you to do it, do it before your weight training workout or, you know, or just do it like the next day.
Speaker BOh my God.
Speaker BSo much good knowledge.
Speaker BOkay, now I'm like planning it out already for the rest of the week.
Speaker AAnd check out, check out my substack.
Speaker ASubscribe.
Speaker AI'm gonna have a great article on that coming out.
Speaker BOh my gosh.
Speaker BAbsolutely.
Speaker BAnd last one.
Speaker BWell, second to last one celebrity endorsed wellness brands.
Speaker AI think it's probably hit or miss on the celebrity and what the brand is.
Speaker AThere's a lot of, there's a lot of fluff out there for sure.
Speaker ABut I think there's probably some good ones in there as well.
Speaker BOkay.
Speaker BAnd fill in the blank on this one.
Speaker BOptimizing midlife isn't about perfection.
Speaker BIt's about consistency.
Speaker BConsistency.
Speaker BSo doing something, a little bit of something every day.
Speaker AYeah, you don't have to go hard every day.
Speaker AYou just gotta go.
Speaker AYeah, exactly.
Speaker BMake that move.
Speaker BSo how many times a week should we be doing the heavy lifting?
Speaker AI would say at least three days a week is, is appropriate.
Speaker AThree to five, depending on the person.
Speaker ABut I would say again, if you can get three to four good, good lifting days in there, that's great.
Speaker BOkay, good to know.
Speaker BAnd cardio.
Speaker ACardio.
Speaker AYou know, there's two different kind of types.
Speaker AThere's the lower key, like zone two, which is like going for a, you know, a fast walk or, you know, things like that.
Speaker AI think you should try to get some of that most days, and then the sort of sprinting and high intensity intervals that at least twice a week I like.
Speaker BWell, thank you so much, Amy.
Speaker BIt's been such a pleasure.
Speaker BYou gave us so much amazing knowledge.
Speaker BNo doubt this is going to resonate with women everywhere.
Speaker BDo you mind telling everybody where they can find you and anything you want them to keep their eye out for?
Speaker AOkay, so it's Dr. Amy, Dr. Amy B. Killen on Instagram.
Speaker AAnd then doctoramykillen.com is my website.
Speaker AAnd then I also have my supplement company, Hotbox is Hotbox Life as well.
Speaker BWell, thank you so much.
Speaker BI really appreciate it.
Speaker BThe name is perfect for this time of life right now.
Speaker BI'm like, I feel like I'm in a hot box most days.
Speaker BYeah, that was Dr. Amy Killen.
Speaker BAnd if you're feeling a little more powerful, a little more informed and a lot more curious right now, then good.
Speaker BThat's the point.
Speaker BBecause your hormones, your libido, your skin, your energy, none of it is just in your head.
Speaker BAnd midlife isn't something to fix, it's something to optimize.
Speaker BYou can follow Dr. Killen at Dr. Amybkillen and check the show notes for links to her clinical work programs and everything she's exploring in the world of regenerative medicine.
Speaker BIf this is this episode gave you clarity, confidence, or even just the language to ask better questions.
Speaker BSend it to a friend and tag us on social media and let us know what resonated follow rate and comment on Apple Podcasts, Spotify, Amazon Music, or wherever you get your podcasts.
Speaker BIt helps the iconic midlife reach more women who are ready to feel powerful in their own skin.
Speaker BFollow the show, share the knowledge.
Speaker BAnd remember, midlife doesn't mean invisible.
Speaker BIt means unstoppable.