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Hello and welcome to the VP Life podcast,

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the show where we bring you actionable

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health advice from needing minds.

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I'm your host Rob.

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My guest today is Simo, a testicular

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cancer survivor who, through trial and

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error, developed a system to help him

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optimize his hormonal

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health and regain his vitality.

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Expect to learn how Simo overcame a

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cancer diagnosis and then tripled his

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testosterone levels, how testosterone is

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optimally produced in the human body, and

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how Simo is able to help clients optimize

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their own levels without the use of TRT.

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Now, on to the conversation with Simo.

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Good morning Simo.

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This one's been a long time coming and

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after a lot of back and forth we were

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finally able to make it happen and I'm

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excited to chat all

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things testosterone with you.

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Timing is actually pretty spot on too as

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we recently hosted Sonya Spill from Vinyl

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Coaching to discuss female health and

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optimization thereof.

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So it'll be good to complete the picture

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in this regard, the male side of things.

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First things first though, your story.

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I know it started on the back end of a

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cancer diagnosis which is what then led

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you down this path to helping men then

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optimize their own testosterone levels.

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So yeah, if you could give us the

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breakdown there and then we can jump into

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the nuts and bolts of

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today's conversation.

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Yes, that was a rehearsed

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part and yes, I'm proud of it.

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Thanks for having me on

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Robert, it's good to be here.

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So, yeah, about 10 years ago when I was

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20, I got the dreaded C word that you

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certainly don't expect but you definitely

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do not expect it when you're at 20 and

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that really was a pivotal point in my

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life because as a young man, I thought I

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was invincible, I thought I could do

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anything and then suddenly my masculinity

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was being questioned in ways that I could

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never have quite

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comprehended to be honest.

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And then I had a procedure, I came out of

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that and then after the operation, I

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started dealing with a lot of low T

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symptoms that really plagued my life

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after that which were low energy, low

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drive, lack of confidence, very insecure

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and so it was a mixture of emotional

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symptoms and physical symptoms around

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gaining muscle and all of these other

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desirable effects that can come from

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having optimized T levels.

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So through trying an error and making

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hundreds of mistakes and trying every

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diet under the sun and all of these

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different modalities and protocols, I

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finally three or four years ago stumbled

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across a protocol that I now call the

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TESTA2X method that got me feeling happy,

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healthy, driven, ambitious, all of these

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kind of aspirational traits as men that

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we need to dominate

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the lives that we want.

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So that's where I'm at now.

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Yeah, those alpha characteristics.

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I'm not a cancer biologist by any stretch

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of the imagination but it is pretty

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fascinating that so many young guys,

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especially sort of well under 40 tend to

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sort of end up with testicular cancer.

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I know it's a bit of a long shot, but can

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you speculate as to why

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that maybe is the case?

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Yeah, I think it's a

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really good question.

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I think it's a really good question

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because I think a lot of people associate

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cancer with something

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you get when you're older.

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They associate it with like genetic

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dysfunction as you get older and it's

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interesting because you've got cancers

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like testicular cancer that are more

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prevalent in younger men from 2030.

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So there's a bit of a kind of paradox you

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could say there, which

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I think is fascinating.

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I think the reason for that, my suspicion

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is our environment has

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become extremely toxic.

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What I mean by that is our exposure to

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heavy metals, to xenoestrogens, to

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plastics, to aluminum and deodorant,

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there's a myriad of substances that are

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now pervasive in a lot of things that we

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kind of take for granted and we just

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assume are innocent and maybe okay when

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actually they're not.

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And if you stack all of these different

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kind of micro stresses up that have all

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these toxins in, whether it's your

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deodorant, your skin care products, your

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foods, your, you

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know, there's a long list.

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If you stack that up over a long period

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of time, you know, the body can become

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overwhelmed and I'm convinced, I'm

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convinced there's a compelling hypothesis

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that the reason I got testicular cancer

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was because at the time I was living a

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very toxic lifestyle and if I think back

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to that time, there was things that I was

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doing that may not have been conducive to

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good testicular health, put it that way.

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Yeah, definitely.

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Yeah, it's definitely a nuanced question

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and it's sort of something I did a bit of

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research into just sort of in preparation

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for this podcast and specifically that

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question because yeah, like I said, it is

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fairly nuanced and I discovered anywhere

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that the testes are formed primarily from

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what are called germ cells and those are

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more likely to develop into other cells

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whereas you have, they are pluripotent,

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whereas you have your things like, well,

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not things, but cells like heart cells

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that generally aren't affected as they

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mature and they're less likely to become

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mutagenic and

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diversifying to other sorts of cells.

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But yeah, I suppose that's a tangent,

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probably something best

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had with an oncologist.

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Yes.

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Yeah, I probably actually

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need to get one of those on.

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Yeah, anyway, testosterone.

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So as you've already alluded to, or one

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of us has, it's an epidemic and there are

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lots of guys with low T at the moment.

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Now you've already alluded to some of the

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reasons as to why that has become, as to

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why it's become such an issue, but do you

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have beyond that any suspicions as to why

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we are, as a society, are struggling,

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well, the men in our society are

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struggling with low T levels?

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Yeah, I think it's a really good question

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because, and I think it's quite a complex

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answer because I think it's so

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multifaceted because I do think if you

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think about what underpins our vitality

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and our vibrancy in terms of how it's

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aligned with high testosterone, it's

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like, well, how do you, what are key

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habits or ways of living that have been

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proven that can be detrimental to

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testosterone levels?

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And I think we're now with screen use and

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our sedentary lifestyle

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and convenience culture.

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I think that's getting increasingly more

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endemic and I think people are finding it

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increasingly more difficult to eat whole,

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eat whole good food, to go and do some

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exercise and move more, get outside.

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All of these kind of basic things that I

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think we take for granted, I think are

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just not as popular as they were, let's

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say 50, 60 years ago.

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And there's a reason why our grandfathers

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had double the

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testosterone that men do now

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in terms of lifestyles that they were

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living relative to now because you just

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didn't have the same amount of stresses.

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And I do think now with phones and the

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culture that we live in, there is a lot

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more, stress seems to be more persistent

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throughout the day, not only

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in terms of the way that we

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approach our work, but also things, you

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know, 56 years ago where they didn't, you

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know, agricultural

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practices were different.

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We didn't use the same amount of

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chemicals that we did.

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Skin, you know, all of the personal care

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products were very different.

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You didn't have the same additives,

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preservatives, all the

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rest of it like you do now.

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So I do think that there is a myriad of

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different elements that are in our

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lifestyle that have evolved really quite

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drastically from 50, 60 years ago.

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And I do think it's for the worse.

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And that's having a huge impact on our

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toxicity load and therefore, you know,

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our body's ability to thrive and feel

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good, you know, as it pertains to

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testosterone and other

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hormones and everything else.

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You know, it's not just testosterone.

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It's so it's very comprehensive.

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Yeah, no, I mean, I couldn't agree more

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on that makes total sense.

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We recently had Dr.

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Jenny Goodman on the podcast and will be

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interviewing Adam

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Parker in the next few weeks.

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And they're both steeped in that side of

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it, the terrain theory of

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why we get unwell to society.

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Yeah, just this high toxic burden that

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then has this trickle down effect on the

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way that mitochondria function and the

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hormones, etc, etc, etc.

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And yeah, it's just it's very simple when

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you understand how these systems break,

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what's more challenging is then sort of

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putting them back together.

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As I found both my own experience and

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with working with with

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with people along the way.

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It's a simple system to break.

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It's that it's not as easy

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one to put back together.

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It's very much a case of Humpty Dumpty.

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Dumpty had a great fall and fell apart

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and all the king's horses and all the

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king's men couldn't put Humpty Dumpty

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back together again.

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I know that obviously hormone

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optimization is to one is

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maybe somewhat easier than that.

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But when you get more complex sort of

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along covid sorts of

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issues, it is it is a problem.

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I would I would add as well, I think

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something that I see a lot of clients is

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like we overlook a lot of people look at

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testosterone and isolation.

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You know, they they see I have got low T

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and therefore they

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think that that's the cause.

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And actually, we mentioned all the

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environmental factors.

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But like, for instance, I see a lot of

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guys that have got dysfunction.

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We know like gut inflammation is

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inversely correlated with with

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testosterone levels.

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The same with cortisol.

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We know cortisol is is is very inversely

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correlated with testosterone.

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And the same with thyroid function.

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If you've got thyroid dysfunction, you

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will not get high testosterone.

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Like you need your

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thyroid to be optimized.

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So there's these other glands and organs

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that we have that are absolutely critical

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for ensuring that testosterone is allowed

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to do the job that it needs to.

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Because if if if those other areas are

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not functioning properly, then there's

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huge downstream consequences.

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I think when you work with someone more

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functional or

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integrative, they understand that.

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Whereas in the conventional space, it's

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not not all of them, but some of them

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tend to be very myopic with regards to

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like you have low T and therefore you

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need to need to correct that with an

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injectable or pellet, whatever it might

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be without kind of

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asking, well, why is it low?

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So, yeah.

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Yeah,

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no, it's it's modern

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medicine is very siloed.

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And I mean, everybody's made this point

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on every podcast going.

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But yeah, if you if you break an arm,

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you're going to any

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there's no question about that.

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But yeah, if you've got a functional

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metabolic disease, you're almost better

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off trying to sort it out yourself

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because the system as it stands is not

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catered to support that that type of

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dysfunction within the body.

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Yeah, you yeah, before we get off topic

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again, I want to come back to the

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discussion a little bit later on.

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But before yeah, before we go completely

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off topic, I'd love to get

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your thoughts on TRT as a whole.

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Now, obviously, it has its place.

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But it's often seen as a sort of a first

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line treatment option for any young man

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or old man for that or

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anyone that's ageism, isn't it?

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I can't say that.

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For anyone who presents as hypogonado or

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with symptoms of low T.

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But yeah, what are your

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thoughts on TRT as a whole?

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Yeah, I think TRT is exploding right now.

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And I think it's part of it's part of a

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greater symptom of this convenience

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culture where, like with anything you

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tend to when you start something you tend

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to there's a bias towards searching for the benefits for the good things about it.

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And you don't tend to search about the

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negatives or the side effects.

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And that, you know, I'm guilty of that.

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I've done that in the past.

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I think, you know, we do that.

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But yeah, whether it supplements, you

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know, you always ask what's the benefits

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of this, you never you never

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ask what's the side effects.

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Right.

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And I think with TRT, I do

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think there's a place for it.

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And I do think if you have pathological

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hypogonadism, where there is genuine

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dysfunction, then then fine, like I think

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that makes that makes perfect that

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there's a reasonable case to be made,

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where even if you were to do lifestyle

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tweaks or adjustments or changes,

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and that didn't work, then I think the

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case for TRT is compelling.

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But I, I at the moment,

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I think too many men

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and a lot of the culture,

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or too many men want

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that instant gratification.

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And I think the it's very easy to just

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associate, okay, well, I have these symptoms of low T.

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And therefore,

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I'll just get injectable or appellate or

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topical, whatever it is that the

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anabargels or whatever it might be.

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And it's a very,

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you know, rather than doing that, the

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hard thing of lifestyle change, i.e.

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changing what you're eating or your

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habits, you know, the TRT presents, it's

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almost like, you know, with pills going

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to a pharmacy, it's

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the same kind of concept.

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It's like, well,

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it's the kind of it's the easy way to rectify something that's nine times out

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of 10, it's going to be solved through

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something that you're doing that's not

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conducive to high testosterone.

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And I know that's a hard thing to

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comprehend, because we don't like to look

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at ourselves in the mirror and be like,

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ah, it's me, we know, we don't want to

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take responsibility, we kind of want to

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outsource and point fingers and blame

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others and say, well, it's not me, it's

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something else that's happening.

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And actually, in my humble experience,

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nine times out of 10, it is

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something that we're doing.

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And it can be innocent, you know, it's not our fault. It's not as if we're

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intentionally trying to harm ourselves.

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You know, it's we're all we're all doing

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the best with what we

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know and what we can.

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But I, I do think a lot of men overlook

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just how easy it is to feel better just

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literally by changing what

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you eat quite, quite literally.

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I see that all the time.

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Yeah, no, again, very sage words.

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And I think what's also important to

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realize is that quite often, if you have

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an underlying issue,

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as you mentioned earlier, maybe some sort

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of disposable underlying infection or

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high amount of toxic exposure that's then

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caused that that low T further

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downstream, then replacing this

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testosterone may not actually give you

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the results that you're after, because

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you're still not dealing with the

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underlying condition, you're just dealing

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with the symptoms thereof.

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So, yeah, it's, it's, it's, it's still, it's still, it's still, it's still, it's

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still it's, it's still, it's a bit of a

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double edged sword, but I still think

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anyone who, even if they have a

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compelling reason to use TRT should still

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look at treating the underlying

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dysfunction as well.

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It's, as you said yourself,

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it's just so multi factorial.

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Just another question off there, have you

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ever worked with guys who've tried to

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come off TRT or who are Yes.

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Yeah.

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Yes.

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And it depends is again, it's nuanced.

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Like, I think it depends how long you've

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been on it, what you've been using, like

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HCG, there's some like, whether like a

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lot of the guys, it's not always TRT and

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there's other, there's

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other factors as well.

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Exactly.

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Exactly.

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And so, depending on the image rule, I

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think there's

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different ways to approach it.

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But it's, it is, it is definitely doable.

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And you can definitely restore, you know,

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a lot of people say, oh, what you lose,

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you know, you tank your fertility, you

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lose your testicular

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function, all the rest of it.

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And those definitely are side effects and

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something to be mindful of, but you using

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the right working with the right person

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and getting the right advice, you can

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rectify it and get that and restore

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natural function, but it

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is definitely delicate.

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It's definitely a delicate one.

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Yeah, no, it's, yeah, you're right.

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And I think what most people don't

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realize is that you don't just come off

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TRT and then sort of instantly

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reestablish a baseline, baseline

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functionality, you're almost at a deficit

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now where you, where you're not

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necessarily just trying to correct low

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levels, you're trying

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to jumpstart the system.

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And then you're, you start to look, you

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got to look at various compounds, maybe

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pharmaceuticals that help

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to essentially get that,

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that, that neurology almost back online.

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Simo, I'd like to

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backtrack slightly if that's okay.

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And maybe chat about some of the

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underlying physiology.

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I know, I know it can

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be a bit denser subject.

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So if you were to help myself in the

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audience understand how testosterone is

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produced in the body, I think it would

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set the tone for the

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rest of the conversation.

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Now, obviously, we don't have to go into

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the sorts of the depths of star protein

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expression and cholesterol transport.

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But yeah, at high level, how does this

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thing that is sort of commonly called the

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hypothalamic gonadal axis operate?

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And how does that then lead on to the

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production of testosterone?

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Yeah, so you've got, there's a delicate

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process with luteinizing hormone, LH, and

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follicle stimulating hormone, FSH.

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Okay.

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And they act like they're almost a good

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way to think about it is they are

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produced from the HbH

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axis in the, in your brain.

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And they, they, it's like pedals on a

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car, like accelerate and brake.

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Okay.

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And what they do is they then the signals

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then come down to the brains and

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testicles, you've got the lady cells and

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the satorine cells, okay.

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And that's, there's a dynamic or there's

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a dynamic that goes on there that helps

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then produce testosterone, which is the

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derivative of cholesterol.

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And that's, that's an interesting point

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we can, we can, we can touch on.

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But, and depending on your, the health of

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the LH and the FSH function, and also, I

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mean, five alpha reductase comes into

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this as well at some point, which I think

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is another interesting point

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that we can, we can touch on.

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But yeah, those, those

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pedals, you want working properly.

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And so, because if they're working

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properly, that whole system with dynamic

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with the brain and the testicles in order

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to produce testosterone, which goes in,

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which is derived from cholesterol, then

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you've got a pregnenolone, and then in

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pregnenolone, you've got DHEA, and then

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you've got downstream

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of that, you then got T.

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And so, assuming that system works, you

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know, everything's done,

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is everything's done fine.

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But you can, you know, a good marker,

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whether it's primary or secondary

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hypogonadism, hypogonadism can come into

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your levels of, you know, whether you've

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got low, very low levels of FSH or LH or

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very high levels of FSH or LH.

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So, the FSH and LH is

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definitely critical.

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Like, if anyone's looking to get markers

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done, like, they're

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definitely a key component.

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But like you said at the start, before we

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went online, like, the

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SHPG is key, albumin is key,

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like some of the binding proteins, and

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then, you know, free T, I think is very

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underrated, people tend to focus on total

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T, and then yeah, your, your DHEA,

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sulfate and pregnant alone.

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So anyway, there's, there's,

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there's, how would you call it?

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There's, there's

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components within that chain.

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Yes.

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And it's very delicate.

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So that's why you've, when you're going

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to approach something like overcoming low

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T, it's what you need to work with

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someone that understands all of these

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different components, so that you're not

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kind of jumping to something whereby it

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may be easily resolvable through some of

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these other components that

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may not be working properly.

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Yeah, I think when someone's struggling,

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they take, they tend to take a very

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reductionist view of things and they, and

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they look for that one solution that's

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been marketed to them as, as being the,

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the one-stop fixall.

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And, and yeah, I mean, obviously, the

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world is on a bell-shaped curve.

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So for some people, that might work, but

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for the majority people, as you've just

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alluded to, they need a more

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comprehensive approach.

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Thank you for that.

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You actually almost answered my next

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question, which was to now differentiate

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the, the difference between, between

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primary and secondary hypergonadism,

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because yeah, I think, sorry, that's,

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that's important to realize, because

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depending on which one you have, you may

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be then better off maybe going down the

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TRT route to begin with.

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But yeah, I'd love it if you could just

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break down those concepts for us.

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And yeah, for sure.

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And I think the easy way to decide for

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this is primary hypergonadism, gonadism,

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is, whereas it pertains

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to tessel slip dysfunction.

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So what, what, what, what we're talking

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about there is like the majority of

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tessel serine in men is

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produced in the ladyx cells.

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Okay.

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It's like, it counts for about 95% of

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circulating tessel serine.

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Okay.

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Whereas, and so if you have, if you have

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dysfunction in the ladyx cells, and to

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some degree, this is

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totally cells, that's

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through that can be from environmental

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toxins, there's a myriad of things that

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can, that can get in the way there, then

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that's what we, that's what we define as

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primary hypergonadism.

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But secondary, what you have

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is positive with the brain.

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So there's a, there's a, there's a

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feedback loop that is where you have the,

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the hypothalamus, okay, it releases

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something called gonadotropin.

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Okay.

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And what happens there is you have the,

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there's a dynamic with the, the

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hypothalamus and the gonadotropin, the

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pituitary, and you have key hormones,

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luteinizing hormone and follicle,

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follicle stimulating hormone.

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And what happens is the luteinizing

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hormone signals to the ladyx cells in the

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testes to start producing tessel serine.

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Like I, like I mentioned, I think

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offline, like you have this, I like to

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call it this kind of, this kind of pedal

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dynamic, like you have in a car, like

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this accelerator and

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this stop-start dynamic.

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And assuming LH function and FSH, FSH

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function are optimized and working well

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and being secreted in the right way,

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you'll be able to then produce tessel

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serine in the right way.

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But sometimes there is factors that come

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into impeding that function, that dynamic

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in the brain that can sometimes inhibit

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LH and FSH function, or sometimes the

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accelerator goes too high and equally

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that can be, that can have negative

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downstream consequences as well.

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So, so primary, think testicles, balls,

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think ladyx cells, okay, secondary, think

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brain, okay, and the signals with the FSH

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and LH that is coming from the pituitary

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gland and the hypothalamus.

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Yeah, no, I think that's, that's, again,

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sound advice and will definitely help.

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The last bit of physiology I'd sort of

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like to touch on is this idea of SHBG.

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Now this is what's called a glycoprotein

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and it's often overlooked.

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Men will go straight to get a

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testosterone check from somewhere like

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MediCheck or wherever, they get one

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online and or just give them this one-off

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reading of testosterone, which obviously

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provides you with some

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level of information,

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but it's also, also a little,

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not disconcerting, what's the word, it

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doesn't tell you the whole picture

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because there's this

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idea of free testosterone.

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So could you sort of enlighten us as to

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the difference between as to what SHBG is

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and why it's important?

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Yeah, so SHBG plays a significant role in

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regulating testosterone.

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It's a protein produced primarily in the

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liver that binds to sex hormones,

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including testosterone in the

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bloodstream, okay, and what you have is

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it combined, it can bind very tightly to

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testosterone and other hormones like for

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instance like estrogen and different like

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estrogen metabolites,

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making it biologically inactive while

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bound, but only the unbound or like the

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free T, the free testosterone, is

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available to enter the cells and exert

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its effects on tissues such as you know

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promoting muscle growth, libido and other

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like antigenic functions.

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So what you'll find is if you have high

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SHBG, more testosterone gets bound,

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reducing the free T.

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So like you'll find that this can like,

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it's very typical that if someone has

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high SHBG, they'll have like decreased

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energy, libido, even muscle mass,

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and the total T can actually appear to be

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normal in that case, but if you have low

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SHBG and more

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testosterone remains unbound.

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So what can then happen is it can then

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free up, you get increasing free

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testosterone and then this can amplify

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testosterone's effects and that's the

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part that you're able then to get the

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effects like associated with high

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testosterone because the free T marker

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really is more synonymous with a more

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credible marker of what's actually

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biologically active that your body can

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actually utilize and do something with.

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So there's definitely factors like

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affecting SHBG levels like for instance

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like this you know like estrogen can

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increase SHBG like health conditions like

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liver because it comes from the liver

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like if you've got liver dysfunction that

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can play into it like thyroid is a huge

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aspect in that as well and like as we've

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mentioned already like lifestyle is key

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so there's definitely like yeah there's

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definitely a myriad of aspects again it

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is quite complex but I do think you know

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like we discussed offline like it's an

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underrated aspect that feeds into the

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testosterone realm that I think a lot of

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people tend to overlook and the same with

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albumin as well to some degree.

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Yeah no these carrier proteins are

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definitely important and they are also

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they're also modulated as you mentioned

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by things like diet and various other

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factors stress is another big one.

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And I think it's also important excuse me

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to sort of note that SHBG can be too low

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as well and then you can which is a point

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you were making earlier excuse me

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regarding thalvatifoloreductase if you

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then have again as you know too much free

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testosterone that can then 5-alfrode use

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into excess DHT which is can also be a

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problem well not only for its

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associations with hair loss but there's

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also some evidence evidence and I mean

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this goes backwards and forwards between

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estrogen DHT and estrogen but there are

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potentially some issues there with the

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prostate as well so point being is that

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you want to have SHBG as I'm sure you'll

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agree and that sort of that happy zone

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not too low and not too high so yeah it's

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something that I think

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guys just generally need to be aware of

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when trying to optimize their levels and

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again why it's imperative to work with

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someone like yourself when sort of

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working their way through this with this

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journey of low T but yeah

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okay so I think we've covered

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we've got a pretty good baseline now of

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of what testosterone is

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how it's produced in the body

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I'd love to pivot into your system though

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I don't expect you to give away all your

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IP but at a high level would you just

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mind us running through how you work with

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people and then maybe an anonymous case

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study just provide a practical example of

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if that would be all right

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just yeah for sure absolutely so what I

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would say is that most men that come to

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me and they are if I kind of set the

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scene for like a context that that I do

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very well or I excel in is where they

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come to me where they're ambitious kind

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of type a type guys and they find that

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despite wanting to put the their kind of

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proverbial foot on the accelerator

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they're not able to get the response they

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want they feel like they're dragging

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themselves the drive isn't there as it

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used to they're just not as sharp as they

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used to be the conviction isn't there and

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they've got this excess weight and

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they've tried different things and they

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can't seem to figure out how to get a

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sustainable result okay so the excess

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weight is there the energy is erratic

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they get a morning burst afternoon they

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start to fight they rely on cultures like

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caffeine same in the evening like you

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know they get back lie on the sofa they

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just kind of zonked out and their

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intimacy sex drive just isn't what it

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used to be like it's something that

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they'll that they will engage in but they

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just the the appetite is gone so that's

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like a typical symptomology of what I

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tend to find and what I do in terms of

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the method is it's usually over three

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months in the first month we focus on

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nutrition and really like I I would say

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80% of guys I work with tend to have some

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form of gut pathology going on where they

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have whether it's constipation bloating

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diarrhea I don't know they seem they have

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normalized some gut symptoms and I do

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think gut health is probably the most

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underrated aspect of testosterone

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optimization and I think hormone

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optimization generally I do think people

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tend to just associate kind of gas and

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some of these gut symptoms is kind of

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normal and that they don't need closer

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inspection and I find when you when you

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put when I put guys on a on a on a on a

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on a protocol yeah and when they start to

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go to the bathroom more regularly and

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their stalls are more normal they tend to

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that is directly correlated with how they

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feel you know they tend to feel better

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they tend to have more energy they tend

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to feel more confident in themselves so

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what we do is I have a bias towards

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making sure the guts in a happy place and

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then we make sure that they're eating in

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the right way so I a lot of these men

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come to me from an intimate and fasting

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background and I think this is an

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interesting point and not not to digress

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but a lot of them tend to eat a big lunch

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and dinner and they forego a breakfast

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and I find that when we reverse that and

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we do a big breakfast and a big lunch and

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we forego dinner they see a radical

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improvement in their subjective state so

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which I know kind of contradicts a lot of

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kind of the a lot of the holistic health

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space is dominated with kind of fasting

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is this kind of panacea and I think I

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definitely think in some cases depending

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on what issue you have I definitely think

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there's I definitely think that's huge

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utility but I think there's nuance to it

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that is often forgotten around like if

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you're if you're nutrient density if your

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stress levels are not in check and the

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nutrient density of the food that you're

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eating isn't high enough then you're

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probably gonna you're gonna be

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undernourished and that will start to in

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some way I don't know break is the right

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word but you'll start to deteriorate and

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I do think a lot of people just think

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that oh well if I shorten my window I'm

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gonna be healthier it's like well no

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that's that's very black and white and

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we've missed a whole there's some found

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key foundations within that within that

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hypothesis that you're that you're

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overlooking and I'm now seeing it

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observationally with clients like every

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single one that shifts to breakfast and

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lunch not lunch and dinner sees radical

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improvements in their sex drive energy

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clarity all the rest of it so I

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definitely think that's a I definitely

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think that that's one of the points that

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I mentioned I think throws the most

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people just because of a lot of the

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holistic health rhetoric that seems to

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dominate you know intermittent fasting

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being this kind of you

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know amazing panacea yeah

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yeah no again I couldn't agree more and I

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think intermittent fasting definitely has

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its place and but when you sort of skip

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breakfast in in perpetuity uh in my

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understanding what happens is that you

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sort of you create this this dissociation

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between your your normal circadian

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biology and your ability to produce

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hormones because I think what most so

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many men miss is that the bulk of

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testosterone production often often not

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all the time sort of happens in the

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morning so when you sort of lose that uh

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that that zeitgeist as it's called that

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circadian cue that uh that basically

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tells your body to to wake up you're then

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losing a lot of that hormonal signaling

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that occurs and and and and that's the

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fact that you've picked up that up is

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incredible and I think sort of shifting

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that schedule around is is genius so

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congratulations that's that's that's a

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great catch cool so I'd love it if we

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could maybe just chat about some

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supplements quickly now I know these are

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thoughts of word uh they're hit and miss

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some of them have some value um and

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ultimately I think the things that move

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the needle are are going to be yeah your

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dietary precursors and and things that

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support testosterone production zinc

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magnesium etc but beyond that though that

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there are a few that that keep on sort of

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crawling crawling out the woodwork things

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like boron tom garelli for dogeo gristers

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um would you mind if we just ran through

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these a few of this quickly and just

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provides your your your thoughts on them

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like perfect thank you

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okay so first one first boron

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I'm not you know what I'm I'm a I'm a fan

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of natural derived boron I'm I'm not a

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fan of synthetic derived boron um uh I

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there is clear efficacy for boron having

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a good effect on 3d levels I've you know

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I I can that's kind of irrefutable but um

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I'm very skeptical generally increasingly

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and this is kind of more this is more of

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a recent change that I've made up upon in

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light of new research about just

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synthetic supplements generally um I'm

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increasingly hesitant anyway I can come

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on to that at the end but we could I

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don't I don't want to digress too much

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but I definitely think um yeah boron has

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its place but you know getting it from

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things like raisins and natural sources

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will will do you better and I don't I

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think a lot of men place a lot of

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emphasis on it as again there's panacea

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at the expense of right well let's focus

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on some of the nutrition fundamentals and

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then we'll layer on top um so and then

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you've got with boron you've got is it um

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you've got borax you've got um you've got

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uh I think what's it called boron

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glistenate you've got different types of

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boron and they have different efficacies

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you know in terms of the form that you

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buy so when you get the supplement itself

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you know it's like with magnesium you've

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got citrate carbonate sulfate and they've

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all they've all they all the body

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responds in different ways depending on

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the form and boron's the same so it's

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important if you're going to do it that

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you get the right type

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perfect answer thank you uh next one

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which is to all the rage is tongue gatali

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yeah tongue gat well it is because of

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huberman you know anything that huberman

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says everyone kind of uh bows down to is

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this kind of he's kind of the overlord um

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which is which is interesting but um so

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tongue cat again it clearly has efficacy

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and I think um and I don't think that's I

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think that's undeniable but I'm skeptical

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I know anecdotally a lot of men that had

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huge digestive issues with with tongue

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cat and again I know with tongue cat um

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and um the sourcing of it depending a lot

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of tongue cat is is um is from asia and

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uh the regulations on like for instance

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when you're looking at herbs you're then

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looking at like heavy metals and um which

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which are definitely uh an underrated

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component in in under in evaluating

Speaker:

whether whether to take it but I I think

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if you can source good stuff that is

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certified certified clean of heavy metals

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and substances that shouldn't be there

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and they and they do exist I think it's

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worth experimenting with at lower doses

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and then I always recommend like titrate

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up never start high and because you're

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gonna there's a high risk but um I don't

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think there's a place for it but I think

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again a lot of the negatives and side

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effects from anac that I've seen

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anecdotally tend to be um tend to be

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overlooked and I think it's I think

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there's a lot of hype there I think

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there's a lot of hype but I would say the

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same thing you probably might yeah you

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might mention fidosia I say the same

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thing about fidosia again like I think

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there's there is some good studies

Speaker:

showing efficacy but I'm skeptical um

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like because a lot of it's done in animal

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models with tomcat it's human I think

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they've done some human randomized

Speaker:

control trials but in fidosia I think

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that it's it's mainly animal models which

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again like animal models give us a good

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indicator they're not they're not

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completely not you know they're not all

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bad but we need more human models I think

Speaker:

really to understand is it you know is it

Speaker:

this really powerful substances that more

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men should take or should more men just

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eat more eggs meat um and these other

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kind of very easy things that you can get

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at your supermarket that I

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think are are way more powerful

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yeah definitely.

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Tonka is an interesting one it seems to

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act as an L.H. agonist um and sort of in

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that way I suppose work in a similar

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fashion to say it may be something like

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hcg but yeah I mean you also can then a

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lot of guys can completely crush their

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shgb on shpg on on tonkats so yeah it's

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uh it's it's something as you mentioned

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you want to titrate out if you're going

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to use it of course um cool uh let's

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stick let's just stick to one more uh

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something that's definitely well known

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and that's ashwagandha

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yeah ashwagandha is I know it's a very

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popular one isn't it I think a lot of

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people take it um for like stress

Speaker:

mitigation as well and I do it's now made

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its way into the testosterone circle and

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I'm you know I'm I'm definitely on the

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spectrum of I'm very uh skeptical of

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ashwagandha and I don't like it I never

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recommend it and because I find it can it

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can create this emotional numbing called

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um I never get the word right it's called

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anhedonia anhedonia that's it yeah and

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there's a lot of cases of men that get

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it's almost like anhedonia is a is like

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um serotonin syndrome where you become I

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mean I've had it myself because I went

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six seven years ago I took

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antidepressants and um and it it really

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messes with your ability to think clearly

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to feel driven to um to feel sharp so

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again I think there's some men that

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clearly take it and and feel good and

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there's benefits but I'm anything in my

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mind that raises serotonin to levels that

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ashwagandha does I don't think is

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inherently a good thing and I do think

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without going down a tangent I think

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serotonin itself is an interesting rabbit

Speaker:

hole just because I think a lot of people

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just associate serotonin with being

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inherently good like you want lots of it

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and actually that you want some but you

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don't want to you don't want to overcook

Speaker:

it like anything

Speaker:

because it can create problems

Speaker:

yeah it's another interesting point is

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the fact that ashwagandha also can to

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some degree inhibit 5 AR expression again

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yes so um that that whole rabbit hole and

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I'm sure we could have the finasteride

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discussion as well yes um but yeah uh

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definitely these compounds are best

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utilized under the guys guide guys one of

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the words one of those words of someone

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who knows what they're doing um cool so I

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don't think we can really have the

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supplement discussion without having the

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diet discussion um I know we sort of uh

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picked around this topic a few times

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already um but what are your views on

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diet now I know there's a uh sorry just

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to complete that there's a lot there and

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uh there's a lot there are a lot of

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people in the carnival keto side space

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and then conversely on the other end of

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the spectrum you've got your vegans and

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bruterians um and I think most of these

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diets have utility at the for the right

Speaker:

person at the right time yeah um but yeah

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broadly speaking uh from a well an

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optimization standpoint and then just a a

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point of of just just life in general

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what are your views on diet

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when it comes to this area

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yeah so I would say I've tried most diets

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I've done vegan pescatarian carnival keto

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uh I've done a lot of them and uh yeah

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I've been deep you know carnivate steak

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and eggs for like seven months which is

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wild um and I do so I do think the best

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diet is the one that's best for you and I

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think a lot of people a lot of people say

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well how do I know that's right for me or

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how do I know it's best for me and I

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understand that and what I would say is

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depending on where I'm a bit different is

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I think the main the main fundamental

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template needs to needs to orientate

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around animal foods because they're the

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most nutrient dense um in terms of the

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amount of your exposure to bioavailable

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nutrients in terms of um nutrients the

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body can actually utilize and do things

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with effectively animal foods are

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infinitely greater than plant foods but

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what I would say is um I see animal foods

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as builders and I see plant foods as like

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cleansers so I'm not like you know I'm

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not like a carnival that things plant

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foods are these kind of evil demons I you

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need you need vegetables because fiber's

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great insoluble fiber's great for getting

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rid of toxins and things in your gut

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shouldn't be there you know fruit I think

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is phenomenal I think it gets wrongly

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demonized um uh you know it's a fantastic

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source of all sorts of nutrients so but

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where I'm where I may be different to

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most people is depending on your latitude

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I think determines on whether you go

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higher carb or lower carbs what I mean by

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that is like you know if you're in

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Iceland for just as an extreme example

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like a more ketogenic template is going

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to be more favorable as opposed to if you

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live on the equator and you've got lots

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of sun um then naturally your your access

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to fat is going to be a lot less like I'm

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in Colombia right now and trying to find

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fatty meat's really difficult trying to

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find anything fatty is difficult because

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it's a warm country so I think the nuance

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that is missed is like where you are and

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to some degree your genetic makeup you

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know um and so what I recommend what I

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recommend to most people is don't be

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dogmatic don't don't because once you

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find that you're in a carnival community

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or a keto community like that's you're

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then part of a cult okay and so what I

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recommend is ever I think all of these

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communities have good things and bad

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things and I think it's wise to

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experiment and be intentional about how

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to experiment and then see and see how

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you react like if you do a more

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meat-based diet um make some subjective

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markers like your energy your sleep and

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then track that for a couple of weeks and

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then maybe go more plant based and see

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how you how you find it and I think by

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doing that you'll then become more aware

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of what you're eating and naturally

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you'll start to find what what your

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version is um so yeah I

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guess that's what I would say

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yeah sort of a very Jack Cruz come Paul

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Saladino take on it I love characters

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yeah no well I mean I do until I try and

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start and try until I start trying to

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listen to what he's talking about I know

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it's funny it's sort of I understand the

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biology uh my background is in biochem so

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I get that aspect of it but when we start

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going to the physics

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robot homes yeah okay

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he doesn't want to dumb it down he is

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insistent and not wanting to dumb it down

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yeah no it's definitely okay so right I'm

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gonna re-listen to that five times and

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then I'm worth it some of it I think he's

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he's just down the road from you well

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he's in El Salvador yeah he's in El

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Salvador yeah so yeah he he's a character

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of note uh on that's for

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sure my my actual claim to fame is I

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lived with Paul Saladino for three months

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in Costa Rica I did you

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yeah three years ago yeah okay

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that that's an interesting one yeah I

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know I emailed Paul our ones just

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regarding uh working with him and at that

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point he was charging $1,200 an hour so

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that was about three or four years ago as

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well so yeah how times have changed but

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um yeah I think you emailed him now you'd

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be lucky if lucky if his receptionist

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replied yeah um but yeah anyway that's uh

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it's strange how the world works anyway

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moving on so yeah I think we've covered a

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lot today and um really what I'd sort of

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like to talk about next I think are your

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views on on biohacking um now I hate the

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term with with the passion but it's what

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the industry's adopted so we kind of got

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to stick with it to some extent anyway um

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but yeah what are your thoughts on the on

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the idea that you can use technology to

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essentially take shortcuts and sort of

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support or augment your production with

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various gizmos and gadgets so

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you know if you'd asked me this four or

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five years ago I would have said oh I'm

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all for it it's great it's amazing um but

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my view on it now is completely different

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in the way that I do think a lot of

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people in health optimization space

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particularly in the holistic health

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optimization space they end up being

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quite neurotic and you end up the

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biohacking or the pursuit of biohacking

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in of itself becomes this kind of

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self-obsessed uh journey that I think can

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mentally impede you and I think it it can

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lead to your your optimization kind of

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forming your entire identity um and so I

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I think I actually think in order to go

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forward I'm a believer in like a lot of

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the best techniques are ancestral like go

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back you know what I mean like eating a

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whole food diet like having a sauna um I

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mean there's a long list but um and I do

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think biohacking has is is dwarfing or no

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morphing into this kind of more

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transhumanistic um abyss whereby um

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there's just this fierce pursuit to want

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to find this marginal gain that the shape

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might not help yeah yeah and and and it's

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incredibly ambiguous you know whether

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you've got the sulfurophane in in um what

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is it in broccoli broccoli sprout yeah

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yeah all the risk there's the resveratrol

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in your yeah like and then you know

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you've got people like David Sinclair who

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who make I you know I

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think he has great intentions

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he's the biggest con artist going

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I think he is as well yeah I think he is

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as well I'm glad you said that I'm glad

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you said that because I he they propagate

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these things these molecules as if as if

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they're this panel this cure all to all

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your problems and it's like it's it's so

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ambiguous it's so ambiguous and and it

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just trades the hell out of me to be

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polite you know um um so I'm glad you

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said that because I think him and his

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other names who are they are they are

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distracting people from just just eat

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just eat right and be consistent that it

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move as much as you can get outside um

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they just do the do the basics and be

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consistent at them stop stop getting so

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caught up in these kind of these other um

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these other things that yeah may or may

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not work because it just you know it

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takes you away from the being present

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from living spending time with family

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kids like there's just a lot of other

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things that I think are more meaningful

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that that will um that will that will

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feed your soul I think that's what I

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think that's what I'm gonna get at in

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summary is a lot of it's quite soulless

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you know uh and I think yeah

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yeah no I sort of look at it as sort of

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technological orthorexia yes

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that's a better way of putting it yeah

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and it's it definitely has its place I

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mean uh things like red light I think can

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be useful but again if you're not

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standing in the sunshine or getting some

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sunshine in daily um there's very little

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point in spending 2000 pounds in a post

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red light uh therapy setup if you're not

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getting in your the rest of the natural

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light spectrum so yeah yeah again it's

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it's they're useful tools but they're

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never going to replace the basics I think

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through all my sort of experimentation

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trials tribulations etc I've come with

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the conclusion that you can't outsmart

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mother nature you you can definitely try

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but you will fail miserably um but yeah

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uh support to the best we'll have to have

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the uh the conversation about who we

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don't like uh offline I think we I've

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just started this but it's it's too early

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to get cancelled uh right okay

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so I would also I would also say like I

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do on one level I understand like we now

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live in a modern environment surrounded

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by emfs and all sorts of things that we

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didn't use to so I do think there's a

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case to some form of biohacking inverted

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commas to some degree just because you

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need modern modern solutions to modern

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problems but I think yeah

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it's just the god sorry go on

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no of course I couldn't agree more and we

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had I had a conversation with Tristan

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Scott who I'm sure you're familiar with

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the real eye computer and we went down

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the wi-fi rabbit and it's yeah no I'm

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definitely a believer in the fact that

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non-atv myth is a problem and as you

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pointed out we then should sort of hack

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our environments whether it's with hard

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wired connections um or not to sort of

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get around those issues but uh ultimately

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we should somehow strive to just create

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an environment where we don't have to

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deal with those problems to begin with um

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which is unfortunately easier said than

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done I mean uh I I have a wi-fi

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connection running now to have this

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conversation with you so it's it's

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definitely finding that a happy middle

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ground I think which and and then yeah

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creating solutions as best you can around

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it um I suppose that is where hacking

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your environment probably is is a good

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thing um okay so I know you've probably

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had just about enough of me by now but uh

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before we sort of start to uh close up

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I'd love to ask your your thoughts on

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testing um and and where you start with

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this when working with clients

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yeah so what I do is I a lot of I'm a bit

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different in the sense of like I alluded

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to at the start like if someone has low t

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it's usually in nearly all cases it's not

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testosterone it's a problem it's it's

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other it's other things going on in their

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hormonal apparatus that is that is

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impacting testosterone so like I alluded

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to the start about thyroid or gut or

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liver okay so for example like with

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testing how that comes into testing is

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like getting you know TSH like in terms

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of the thyroid profile getting the

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relevant markers done in thyroid in terms

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of liver giving the relevant markers

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tested within the liver function and the

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same to some degree gut if we can

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depending on on the symptoms but I we we

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establish a hormonal baseline based on

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like for instance like you've got

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prolactin you've got you know even what

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else is involved in their thyroid liver

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prolactin I mean there's there's there's

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estrogen yeah exactly exactly um so that

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there's there's numerous key hormones

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that depending on the testing will help

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determine how we then approach things and

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they give us a really good indicator

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really solid indicator of like for

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instance you know you've got thyroid

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dysfunction well well that's well there's

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your there's your answer as to why the

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other two or it's the same with like gut

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function I mean so it's once you

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establish that baseline it's then very

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easy to understand okay cool this is how

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we need to then tailor the approach to

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make sure that you're getting that you're

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getting an individual an individualized

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um personalized personalized yeah

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approach that um ensures that it's

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relevant for you and that you're not

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being kind of crowbarred into a box and I

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think that's where and I think testing I

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absolutely think testing has its place

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and I but I do think testing isn't as

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objective as people think it is like

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you've got you know I believe in saliva

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testing for cortisol and dha sulfate I

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think it's more credible than blood

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testing because you um and so I do think

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there's some cases to be made for like

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for instance like if you want to be heavy

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metals you know doing urine and blood not

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hair um so again it's it's nuanced um uh

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I think blood testing has its place but I

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think along with like I mentioned the

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examples there and along with your

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subjective state you know for instance

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the thyroid taking your temperature in

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the morning seeing if it's um at the

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right level your heart rate if you've got

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you know an extremely low heart rate it's

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not always favorable that can be

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indicative of you've got um some maybe

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some like low old old dusterone or you've

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got um you know uh thyroid dysfunction so

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it's yeah it's testing's key it has its

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it has its place but it definitely has

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its pitfalls and I definitely think the

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subjective state can say a lot as well I

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think um it's it I think it's making sure

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that you're recognizing all of it so that

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it's a very holistic picture

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comprehensive yeah are you doing any

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specific gut testing sort of organic

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acids uh GI maps anything like that

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yeah do you know the GI maps is something

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that we'll do I think that's a really

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good one I think that's definitely one of

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the better ones in the space um so um

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we'll we'll dig into we'll dig it we'll

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we'll do that if it's if it's appropriate

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but I I do find depending on the the

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extreme how extreme the the symptoms are

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as it pertains to the gut um in most

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cases it's it's usually pretty usually

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pretty resolvable through just making

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some nutritional and supplement tweaks

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but if we if for the reason those don't

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work then we will we will then resort to

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more comprehensive testing

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using like you said GI maps

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yeah I think we're on a similar

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wavelength there and I think what most

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people um especially if they're not if

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drugs aren't their first protocol um fail

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to realize is that the interventions are

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largely uh the same uh through uh

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irrespective of the person so testing

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doesn't necessarily have to come straight

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off the bat because you unless you are

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maybe looking for something specific like

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a thyroid issue like you mentioned um but

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when you start to make those necessary uh

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changes as as within your protocol for

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example most people will start to sort of

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universally improve as a result of those

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of those um processes uh being

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implemented so I I think testing is great

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but it doesn't necessarily have to be run

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initially it can be run as a

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troubleshooting point further down the

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line if necessary uh necessitated uh

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versus yeah as a well we've got to test

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you at baseline to establish where you

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are well we know where you are where you

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are is rubbish so let's improve from

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there and then track later on

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yes exactly yeah

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cool okay I see well I think yeah as I

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mentioned we've covered a lot so maybe to

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end off um we could just run through some

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rapid fire questions and lightning round

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as it were and uh we can yeah uh call it

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a day then would that be okay yeah sounds

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good okay cool brilliant so if you had to

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choose just one lifestyle change to boost

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testosterone levels more than the

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eat more eggs

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perfect okay what's the most common

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mistake guys make when trying to increase

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testosterone levels relying on

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supplements can women benefit from these

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same principles yes what's the one over

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the counter supplement you would turn to

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if you could pick only one

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topical magnesium chloride

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perfect and a controversial one to end up

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end off with a scrotal

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sunbathing yay on a sorry

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yay yay if it's appropriate

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fair enough yeah um do you know this has

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been an amazing conversation where can

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people find you yeah

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so on twitter I'm just uh simo um that's

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that's the best place

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okay brilliant we'll link to uh all your

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social uh excuse me the socials in the

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show notes and uh yeah thanks again this

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has been an amazing conversation

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yeah thanks for having me Rob it's been

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great it's been great to chat to you