This podcast is for you, the Modern Man. I'm Dr Anne
Anne Truong:Truong, your host. I'm an intimate health medical doctor
Anne Truong:and best selling author of the book, Erectile Dysfunction Fix.
Anne Truong:I'll do a deep dive into sexual health and performance and how
Anne Truong:it affects men of all ages and backgrounds. So let's get
Anne Truong:started, and be sure to visit my website at
Anne Truong:sexualhealthformmenpodcast.com for more information and
Anne Truong:resources from the show. See you on the inside.
Anne Truong:Men, are you struggling with ED? In this episode, I'm having a
Anne Truong:unique conversation with Dr. Mohit Khera from Baylor College
Anne Truong:of Medicine, a world renowned urologist and an expert in
Anne Truong:erectile dysfunction. He will share his perspective on
Anne Truong:treatment for erectile dysfunction and discover how you
Anne Truong:can regain your confidence and your sexual vitality again. You
Anne Truong:do not have to live with ED. So stay tuned for this whole
Anne Truong:episode. I will guarantee, you will learn something powerful.
Anne Truong:Hello there, modern man. In today's episode, we have one of
Anne Truong:the best urologists in the country, Dr. Mohit Khera,
Anne Truong:because I have been admiring his work for years, and we both
Anne Truong:graduated from the same program. So Dr. Mohit Khera is the
Anne Truong:professor in Department of Urology at Baylor College of
Anne Truong:Medicine, and holds the F. Brantley Scott Chair at urology,
Anne Truong:we'll dive into what that means, and he has published hundreds of
Anne Truong:research papers on men's sexual health, and is really the
Anne Truong:leading researcher and clinician in men's sexual health. I am so
Anne Truong:honored to have him here today in our episode. So welcome, Dr
Anne Truong:Khera.
Anne Truong:Dr. Mohit Khera: Thank you so much for having me on the show.
Anne Truong:Okay, so I'm gonna ask you some questions that I
Anne Truong:wanted you to share from your perspective. What is the latest
Anne Truong:in men's health at this time? What's working? What we're
Anne Truong:finding out that may not work? Because I know you on the cusp
Anne Truong:of research and about to do great research coming up, and
Anne Truong:I'm going to be following you and as listener, follow him,
Anne Truong:because he is the best in what he does in male sexual health.
Anne Truong:Dr. Mohit Khera: Thank you. That's a loaded question,
Anne Truong:because there's so much innovation and change going on
Anne Truong:in men's health and sexual health as we speak right now.
Anne Truong:But I think the biggest thing for me is this full paradigm
Anne Truong:shift from being proactive and reactive historically, when in
Anne Truong:sexual dysfunction, we've been very reactive. We wait till the
Anne Truong:man gets erectile dysfunction. He comes into my office, I give
Anne Truong:him Viagra, and he goes on his way. That is reactive. And what
Anne Truong:we're now seeing is we're changing the paradigm. We're
Anne Truong:being proactive. We're preventing the erectile
Anne Truong:dysfunction from happening in the first place, and how do we
Anne Truong:do that? Diet, exercise, sleep, stress reduction. People are
Anne Truong:becoming much more aware of their bodies and preventing it.
Anne Truong:They're taking more care into their hormone profiles, looking
Anne Truong:at their testosterone level, women, for example, their
Anne Truong:estrogen, testosterone, progesterone, and we're also
Anne Truong:focusing on regenerative therapies. I know we talked
Anne Truong:about that earlier, just about stem cells and PRP and shock
Anne Truong:wave. And now we're looking into new things such as radio
Anne Truong:frequency, potentially hyperbaric oxygen. So there's a
Anne Truong:lot of new things on the horizon. But I think the biggest
Anne Truong:thing for me, and I think the most interesting, is this
Anne Truong:paradigm shift of shifting from, let me just give you Viagra. I'm
Anne Truong:actually going to give you a treatment like diet exercise,
Anne Truong:sleep and stress reduction.
Anne Truong:Wow. So that's a loaded question. What does that
Anne Truong:mean? Can you clarify diet, exercise, sleep and stress
Anne Truong:reduction, so our listener can have an idea what really that
Anne Truong:mean?
Anne Truong:Dr. Mohit Khera: Yeah, let's take a step back. If you look at
Anne Truong:all the podcasts that we're listening to today. You're going
Anne Truong:to hear two big buzz words. The first word is lifespan. The
Anne Truong:second one is health span. You hear health span and lifespan
Anne Truong:over and over again. And so Anne, you and I both want our
Anne Truong:health span to last as long as our lifespan. I don't want to
Anne Truong:live till 80, but only be healthy till 60. That would not
Anne Truong:be good for me. Well, interestingly, most people think
Anne Truong:about their sex ban. Your sex band is the portion of your life
Anne Truong:where you'll be able to engage in satisfying sexual activity.
Anne Truong:We, most of us, want our sex band to last as long as our
Anne Truong:lifespan, and so that's very important. And so how do you do.
Anne Truong:Diet? Well, many of the techniques that you're hearing
Anne Truong:online and hearing on these podcasts of how to improve your
Anne Truong:health span is are the same things that improve your sex
Anne Truong:span. So when I talk about diet, diets that typically are anti
Anne Truong:inflammatory, that have high antioxidants, a low glycemic
Anne Truong:index, typically have more impact on improving sexual
Anne Truong:function. The one that's quoted the most is the Mediterranean
Anne Truong:diet. We have the most data on the Mediterranean diet for
Anne Truong:sexual dysfunction. Now, I don't think the Mediterranean diets
Anne Truong:right for everybody, and I think what's unique about the
Anne Truong:Mediterranean diet is it does have it's very high
Anne Truong:antioxidants. It's a low inflammatory diet. We talk about
Anne Truong:sleep. Do you need at least seven to eight hours of sleep a
Anne Truong:night to help improve your sexual function. If you get less
Anne Truong:than six hours of sleep per night, it actually is
Anne Truong:detrimental to your sexual function. It can actually impair
Anne Truong:sexual function. Some people say, Well, Doctor, I heard, the
Anne Truong:more sleep I get, the better sexual function I'll have. But
Anne Truong:that's not exactly true. Roughly around nine hours, it plateaus.
Anne Truong:So sleeping 12 hours doesn't make your erections better. You
Anne Truong:really want to be in that sweet spot of seven to eight hours,
Anne Truong:and remember that it's not just the amount of hours you sleep.
Anne Truong:We also talk about quality of sleep, right? So you want to
Anne Truong:have good quality, good REM good, deep sleep. And you also
Anne Truong:want to mitigate sleep disorders, the number one sleep
Anne Truong:disorder causing sexual dysfunction in the world is
Anne Truong:sleep apnea. Sleep Apnea significant increases sexual
Anne Truong:dysfunction. The number two disorder in the world is
Anne Truong:insomnia. So just be careful, if you have these conditions,
Anne Truong:addressing those conditions can make a big difference.
Anne Truong:Wow. So I want to kind of circle back a little bit
Anne Truong:when you say, why is there a paradigm shift from reactive to
Anne Truong:preventative? Now, what has happened that created that?
Anne Truong:Dr. Mohit Khera: I think the biggest is social media and
Anne Truong:podcasts. People are listening to social media. They're
Anne Truong:listening but they had, did not have this vehicle in the past.
Anne Truong:And that is really important. If you look at the health podcast,
Anne Truong:look just like this one. Now. People are getting their
Anne Truong:education through you, not through the newspaper anymore,
Anne Truong:not through the TV anymore. They're getting their education
Anne Truong:through you. And what you'll see on many of these podcasts is
Anne Truong:they're talking about improving health, improving the quality of
Anne Truong:health, and being proactive about your health. Whether some
Anne Truong:people talk about red light therapy, they talk about
Anne Truong:meditation, and mindfulness. I mean, everything is about
Anne Truong:So I love how you use the word sex span. That's the first I've
Anne Truong:improving your health, and so these in effect, are actually
Anne Truong:improving your sex being it's the same thing. Let's take
Anne Truong:exercise for a second. We published a paper two years ago
Anne Truong:showing that exercise alone, just exercise, significantly
Anne Truong:reverses erectile dysfunction. In our study, we looked at 11
Anne Truong:meta analysis, and it was on average 40 minutes four times a
Anne Truong:week. That's all you gotta remember. 40 minutes four times
Anne Truong:a week. It's 160 minutes over a period of six months,
Anne Truong:significantly increased the IIEF for the erectile function
Anne Truong:scores. What's so interesting is the more severe the erectile
Anne Truong:dysfunction you had, the greater the improvements in IIEF scores,
Anne Truong:and that's just with exercise right now, if I tell someone to
Anne Truong:do 40 minutes of moderate to vigorous exercise four times a
Anne Truong:week, I will significantly reverse and improve their sex
Anne Truong:band. But guess what, Anne, I'm also going to improve their
Anne Truong:health. I'm also going to improve their lifespan. I mean,
Anne Truong:I get other benefits besides just improving their sex band.
Anne Truong:So I think the same principles that we use for health span and
Anne Truong:lifespan absolutely apply to sexpan.
Anne Truong:heard of it, and it's almost like, Hey, if you improve your
Anne Truong:sexual health, you will live longer. So that may motivate
Anne Truong:people to correlate both of it, because everybody want to live
Anne Truong:longer and be healthy and have quality of life. But what we
Anne Truong:find out in this view, is that it's so hard to motivate people
Anne Truong:to exercise.
Anne Truong:Yes, no, I agree, but I will tell you very interesting story.
Anne Truong:There was a study that came out of Saint Louis, and they were
Anne Truong:looking at young men, 18 to 40, and they looked at them coming
Anne Truong:in with a diagnosis of ED and they would screen them for
Anne Truong:diabetes. And what they found was that roughly 30% of the men
Anne Truong:who came in for a diagnosis of erectile dysfunction had
Anne Truong:actually pre diabetes or diabetes on diagnosis, that's a
Anne Truong:lot of people, 30% now I want you to think about when you and
Anne Truong:I were 3025, 30. We don't go see the doctor a 28 year old I'm not
Anne Truong:going to go in and go get my blood pressure checked. I have
Anne Truong:other things to do. I'm not going to go in and get my
Anne Truong:cholesterol, my sugar checked. But if a 28 year old man gets
Anne Truong:erectile dysfunction, he is the first person at my door tomorrow
Anne Truong:morning saying I got a problem. And why is that important?
Anne Truong:Because I believe that sexual dysfunction is the gateway to
Anne Truong:treating all the other medical conditions. If he's going to
Anne Truong:come in for that moment, I have a window and opportunity. Unity,
Anne Truong:to screen that hemoglobin A1C to look at those lipids, to see
Anne Truong:what else is going on with his health. And if I tell him that,
Anne Truong:if you improve your blood sugar, you will actually improve your
Anne Truong:sexual function, many men are more motivated do that than if I
Anne Truong:just say, Hey, you got pre diabetes. Keep an eye on it.
Anne Truong:Let's try to improve it, they will be more motivated to take
Anne Truong:care of their health. Do sexual function, and that, in a way,
Anne Truong:has a trickle down effect on all the other comorbidities.
Anne Truong:So that's going to lead me to the next two
Anne Truong:questions. So, since we're talking about younger men,
Anne Truong:what's going on? Why are we seeing younger men now with ED?
Anne Truong:We should see that more in the men over 60 or 50. Why? What's
Anne Truong:going on?
Anne Truong:Dr. Mohit Khera: Let's look at many different reasons why.
Anne Truong:We'll start with just a general statement about the population
Anne Truong:is becoming more unhealthy decade after decade. If I showed
Anne Truong:you a graph of obesity, diabetes and metabolic syndrome, a graph
Anne Truong:and I show you decade by decade, the percentage of men who have
Anne Truong:obesity, diabetes and metabolic syndrome from the ages of 18 to
Anne Truong:40, you're going to see it skyrocketing in the United
Anne Truong:States like this, and that lines in the mimic ED rates in men, as
Anne Truong:well as population because diabetes is the number one risk
Anne Truong:factor of having ED four times more likely obesity. All of
Anne Truong:these conditions also significantly drop serum
Anne Truong:testosterone levels, no question. So as I drop the serum
Anne Truong:testosterone level, as I become more obese, diabetes, these are
Anne Truong:comorbidities that will take a hit on erectile function. Number
Anne Truong:three is that there is now a era of social media, and what's
Anne Truong:happening is the porn has significantly increased, and
Anne Truong:when you see a significant amount of pornography. What
Anne Truong:happens is your expectation is far greater than your reality,
Anne Truong:and so that delta can cause many of these men to develop erectile
Anne Truong:dysfunction. So we ask them, Do you have many men? Say, look, I
Anne Truong:have ED. I can't get erection. I say, How about by yourself? Oh,
Anne Truong:no problem. Okay, then now I got the idea, if you have
Anne Truong:masturbation, I have no issue. How about in the morning when
Anne Truong:you wake up? No issue. But with my partner, I have ED, what
Anne Truong:they're telling you is they have psychogenic ED, and I've seen
Anne Truong:the rate of psychogenic ED go up, and I think it has to do
Anne Truong:with porn. I think it has a lot to do with social media and the
Anne Truong:lack of interaction we all have now, most of our interactions
Anne Truong:with the phone and not with other people.
Anne Truong:Well, not to mention now AI. I was at a
Anne Truong:conference, and now I'm looking at chat GPT, and you can
Anne Truong:converse with it. Now there's a voice chat GPT, you can converse
Anne Truong:with that. Even give it a name, will be as if you're talking to
Anne Truong:a person. So imagine that if you're at home, you can talk to
Anne Truong:somebody else that could you could give it a name, it's like
Anne Truong:you don't even have to leave the house anymore now, right?
Anne Truong:Dr. Mohit Khera: Right, but, but now there's a whole era of
Anne Truong:marketing coming out with sexual AI. In other words, you can find
Anne Truong:a partner online who will talk to you. And there was one study
Anne Truong:that I just wasn't a study. It was just a it was an article
Anne Truong:describing a gentleman who had fell in love with his AI bot
Anne Truong:wanted, and you have to pay every time you talk, and
Anne Truong:roughly, spend almost $2 million and trying to keep this
Anne Truong:conversation going and this relationship going. So I think
Anne Truong:it's you just gotta be careful, because I think AI and what's
Anne Truong:happening in the world of Sexual Medicine is going to change
Anne Truong:drastically.
Anne Truong:So what you were saying that the person was not a
Anne Truong:person. It was an AI you were talking to?
Anne Truong:Dr. Mohit Khera: Right. Fell in love with, could not stop
Anne Truong:talking to, was sexually attracted to, and it was, I
Anne Truong:believe it was, roughly $2 million astonishing number. But
Anne Truong:in other words, you just have to realize that these AI bots and
Anne Truong:the area of Sexual Medicine is growing. There are now Virtual
Anne Truong:Reality places that you can go into to have sexual encounters
Anne Truong:with AI bots as well. So it's changing our field of sexuality,
Anne Truong:and how we perceive sexuality. How we have sex is changing.
Anne Truong:So what are your views on that when we're now
Anne Truong:moving to virtual reality and so forth. Obviously not good,
Anne Truong:because we're social being, and we're taking away that touch and
Anne Truong:feel, that sensation. What are your views on that?
Anne Truong:Dr. Mohit Khera: So I'm personally against it at this
Anne Truong:point. I mean, I just feel that there's something important
Anne Truong:about the human connection. There's something important
Anne Truong:about being intimate with another person. It's my personal
Anne Truong:opinion. I think there are others that say this is great.
Anne Truong:You do things on your own. And personally, I do feel that it's
Anne Truong:important to have the human connection, keep the intimacy
Anne Truong:and keep that relationship going with another person. I think
Anne Truong:it's important.
Anne Truong:You just give me an idea for my next episode to talk
Anne Truong:about virtual reality, virtual AI, so another question was that
Anne Truong:you give me the scenario of a younger man who's more motivated
Anne Truong:because he has ED and that is a gateway for opening a gateway
Anne Truong:for better health for him down the road. What about I wouldn't
Anne Truong:say older, but a man over 5055, that has. ED. What would be your
Anne Truong:approach for him versus a younger male in their 20s?
Anne Truong:Dr. Mohit Khera: Sure, you know most of the time, the younger
Anne Truong:patients are more likely to have psychogenic ED, so you just want
Anne Truong:to be careful about asking about getting morning erections and
Anne Truong:masturbation. But older men typically have comorbid
Anne Truong:conditions that they've acquired that have now caused them to
Anne Truong:have erectile dysfunction. And my only wish, my only hope, was
Anne Truong:that I had had to had the opportunity to meet them earlier
Anne Truong:in life, to where I could change the trajectory so they're not
Anne Truong:coming to me at 55 and we could have done things earlier to
Anne Truong:prevent the ED from happening at that time. Maybe it would have
Anne Truong:been lifestyle modification, could have been hormonal, could
Anne Truong:be with your partner. So those are things that you think about.
Anne Truong:But if he comes in, obviously, I want to first look at everything
Anne Truong:that could be hurting his erectile function, modifiable
Anne Truong:risk factors. Maybe it's an SSRI, an anti androgen. Maybe
Anne Truong:they're on finasteride. Maybe they're on something that's
Anne Truong:causing them to have the ED. So you want to take away the
Anne Truong:enticing so whatever's causing the ED away, then you want to
Anne Truong:look at other modifiable risk factors. And we talked about
Anne Truong:this earlier, but it's lifestyle modification, diet, exercise,
Anne Truong:sleep, stress reduction. I want to optimize the hormones,
Anne Truong:particularly the testosterone level. Optimizing the
Anne Truong:testosterone can significantly help this patient. And then once
Anne Truong:you've done all that, you have to make sure you ask about the
Anne Truong:partner, and I'll just give you a story. When I finished my
Anne Truong:Wow. So what you're saying is that if you treat one
Anne Truong:fellowship, I was very proud of myself, and I was able to get
Anne Truong:these men, these amazing erections, great, livid, and
Anne Truong:they would go home and they would have noone have sex with,
Anne Truong:because their wives would say, one woman called me. She said,
Anne Truong:Look, things were great until he met you, and now we fight all
Anne Truong:the time because he wants to have sex and I don't, and we
Anne Truong:haven't had sex in 10 years. And now we fight all the time, and
Anne Truong:it's because of you. And I thought to myself, she's right.
Anne Truong:I mean, either leave both libidos low or leave put both
Anne Truong:libidos high, but you never put one high and one low, right?
Anne Truong:That's a big mistake. And so very quickly that year, I flew
Anne Truong:out, I spent some time with Erwin Goldstein, who's the god
Anne Truong:bother of female sexual dysfunction. Went a lot of his
Anne Truong:courses at ish wish. And for 6017, years now, I've been
Anne Truong:treating women. Because by treating the woman, I'm actually
Anne Truong:treating the man. By treating the man, I'm actually treating
Anne Truong:the woman. The best examples I can give you. And have you and
Anne Truong:have you seen this over and over again? Erwin Goldstein did a
Anne Truong:study with Levitra. He took men and he gave half the men
Anne Truong:Levitra, Half the men placebo. He said, I don't want to meet
Anne Truong:your female partner, but can you give her this questionnaire at
Anne Truong:the beginning and the end of the study? It's called the fsfi
Anne Truong:female sexual function index, most commonly used. He gave the
Anne Truong:questioner to all the women at home, what he found was that
Anne Truong:those men who had the Vitra had an improvement in the rectal
Anne Truong:function. Those women at home also had a significant
Anne Truong:improvement in their female sexual function, meaning
Anne Truong:arousal, libido, orgasmic function, and those men who got
Anne Truong:placebo, those women, saw no improvements in their sexual
Anne Truong:function. So think about this, and I am actually treating a
Anne Truong:woman by just treating the male partner, I'm seeing significant
Anne Truong:improvements, just like I'd see if I gave her a pill or I gave
Anne Truong:her testosterone. And we did studies showing the opposite. If
Anne Truong:I treat her and I skyrocket her libido. Guess what happens? His
Anne Truong:erection is improved, so it's linked. You can't just treat one
Anne Truong:person without addressing the other person at home.
Anne Truong:partner, the other partner will also improve, even though you're
Anne Truong:not directly treating their spouse or significant other.
Anne Truong:Dr. Mohit Khera: Absolutely. Absolutely well documented, well
Anne Truong:shown. So when I treat that male partner in my office or that
Anne Truong:female partner in my office, I know that the sexual function of
Anne Truong:the other partner at home will improve. The problem is, is that
Anne Truong:we have to actually address what's going on like the biggest
Anne Truong:mistake you can do is give the man via Go and tell me the home
Anne Truong:not even ask about the female partner. What if this partner
Anne Truong:does not want to have sex? What if this partner is there's an
Anne Truong:issue, there's something you want to address them both as a
Anne Truong:couple, if you want to improve the efficacy of that whole
Anne Truong:relationship, giving him Viagra and telling him to go is not the
Anne Truong:solution. You need to say, Tell me about your partner. Is she
Anne Truong:post menopausal? Does she have pain with intercourse? Anyone
Anne Truong:who has pain is going to avoid the activity the house or
Anne Truong:libido. Any issue with arousal? Has there any issues with
Anne Truong:orgasmic dysfunction? How is the quality of the relationship? Oh,
Anne Truong:have you seen my sex therapist? She's amazing. So there's things
Anne Truong:you can do to make that much better, but the handing the
Anne Truong:Viagra and saying goodbye is a mistake.
Anne Truong:I love that, and I encountered this a lot, where
Anne Truong:we'll treat the men and their functioning, but the women who
Anne Truong:are maybe in their 50s or 60s, or going to menopause and 10,
Anne Truong:you know, we're done. We have kids out of the house. We're
Anne Truong:done. I'm not interested in sex anymore. How do you address that
Anne Truong:scenario?
Anne Truong:Dr. Mohit Khera: So it depends on what the problem is. Let's
Anne Truong:define what female sexual dysfunction is. FSD has four.
Anne Truong:Components, decrease libido, decrease arousal, orgasmic
Anne Truong:dysfunction, or pain within a horse. If you have one of these
Anne Truong:four, and you're bothered by the condition, you suffer from FSD.
Anne Truong:So if a woman comes in and says, I have low libido, but I really
Anne Truong:don't care, not bothered by it, I say, okay, then you don't
Anne Truong:suffer from FSD. How many women in the United States suffer from
Anne Truong:FSD, 43 to 48% that is a lot of women. 43 to 48% how many of
Anne Truong:those women actually get therapy? Less than 9% so that is
Anne Truong:a big population of women that are suffering in silence. I call
Anne Truong:that suffering in silence. Many of them say, I don't know where
Anne Truong:to go. Many of them, when they go to their OB GYN say they
Anne Truong:don't want to treat it, they don't treat FSD, and so they
Anne Truong:just try to find ways to get cures for this problem. And it's
Anne Truong:actually very sad there should be better resources. The other
Anne Truong:problem is, there's very minimal research in FSD. We have a lot
Anne Truong:more research in ED, erectile dysfunction, but the amount of
Anne Truong:money that we spend on FSD is a fraction of what we spend in
Anne Truong:men, but in either case, if she has those symptoms, then we try
Anne Truong:to figure out what is the best way to address it. I think that
Anne Truong:looking at the triangle is very important. For me. The triangle
Anne Truong:is estrogen, progesterone and testosterone. Most people only
Anne Truong:look at estrogen, progesterone, you have to look at testosterone
Anne Truong:in women. Is extremely important. It's the number one
Anne Truong:driver for sexual desire in women, even more than estrogen.
Anne Truong:In fact, a woman makes more testosterone in her body than
Anne Truong:she does estrogen. So we have to look at the triangle. We look at
Anne Truong:the outside triangle, which is cortisol. We look at that
Anne Truong:thyroid, which is very important, a growth hormone, any
Anne Truong:other outside hormones that we can look at are very important.
Anne Truong:And then don't forget, I think I tell the woman, this is a 5050,
Anne Truong:you're going to help me with diet, exercise, sleep and
Anne Truong:stress. Most women I can see start doing some exercise. They
Anne Truong:do some change your diet. It's the sleep and stress in women
Anne Truong:that I see take a big hit. And if a woman is fatigued, let's
Anne Truong:say she's exhausted. It's 10 o'clock at night and she has a
Anne Truong:choice between sex and sleeping, she's most likely to sleep. I'm
Anne Truong:just going to tell you right now, a man, he still makes you
Anne Truong:sex, even if he's tired, but a woman is typically going to say
Anne Truong:and especially on stress. Think about this, many men use sex to
Anne Truong:relieve their stress. That's a common thing. Many men use sex
Anne Truong:because women typically have to relieve their stress in order to
Anne Truong:have sex. It's kind of the opposite. And I tell these men,
Anne Truong:I say, Look, you want to engage in sexual activity with your
Anne Truong:wife, take her to Hawaii, take her on a trip. Relieve her
Anne Truong:stress, help her with anything she can, and drop her stress
Anne Truong:level. Her desire will go up, but take her out of the
Anne Truong:stressful environment. So again, we're different, and I think
Anne Truong:it's really important to understand her situation, what's
Anne Truong:going on, but to not address the female partner when you're
Anne Truong:taking care of the male patient, I think, is a mistake.
Anne Truong:And now, do you always do that? When you treat
Anne Truong:the male you also encourage their female partner to come in
Anne Truong:Dr. Mohit Khera: I do many times they don't, but I will go
Anne Truong:as well.
Anne Truong:through the same question or ask the male patient, tell me about
Anne Truong:her desire for sex. Tell me about arousal. Do you have any
Anne Truong:pain within a course? How old is she? She post menopausal? She
Anne Truong:don't any hormones? Is she on any SSRIs that's going to set
Anne Truong:down her libido and say, I'm always willing to help. But many
Anne Truong:women don't feel comfortable. Sometimes they say, Look, I have
Anne Truong:a little libido, but I'm happy with it. I say, great. So that's
Anne Truong:fine. So some couples do come in together, which is great, and
Anne Truong:that's a great discussion. Some women come in after I see the
Anne Truong:male, then they'll come in afterward and say, Look, my
Anne Truong:husband told me that you may be able to help. And I say, Great,
Anne Truong:let's talk. But when they come in, it's not just about handing
Anne Truong:her hormones and pills like it's not just about giving her
Anne Truong:estrogen, progesterone, handing her some testosterone, some
Anne Truong:vaginal estrogen, and saying goodbye, we go heavy, heavy
Anne Truong:lifestyle modification. Um, she's gotta help me with the
Anne Truong:lifestyle modification, whether it be weight reduction. Now, I
Anne Truong:have found one thing that's actually helped a lot of men and
Anne Truong:women, more than even hormones and when it comes to sexual
Anne Truong:dysfunction, and that's weight loss. You know, when a woman
Anne Truong:loses 3040, pounds, she feels amazing. She feels like a new
Anne Truong:person, new clothes, new outlook, self image skyrockets,
Anne Truong:and obviously helps with the joint pain and the blood sugars
Anne Truong:and the hypertension and the cholesterol. I mean, a lot of
Anne Truong:other things improve as well, but we use a lot of GLP1 in the
Anne Truong:Select population of patients, and putting him or her on the
Anne Truong:GLP1 has really made a difference in my practice.
Anne Truong:So you put them on GLP one and on a hormone
Anne Truong:replacement therapy at the same time, or use diagram, yes,
Anne Truong:Dr. Mohit Khera: it's synergistic. So remember this,
Anne Truong:and we're almost done with this. We're doing a trial now at
Anne Truong:Baylor, where if you give someone a GLP1 agonist, they
Anne Truong:actually can start seeing a loss in muscle mass too.
Anne Truong:Unfortunately, because you're decreasing your caloric intake
Anne Truong:and the muscle mass will go down in hypogonadal patients or women
Anne Truong:with low T if you put them on testosterone and ask them to
Anne Truong:lift weights, to lift muscle mass, then we don't see a
Anne Truong:significant decline in muscle mass, because testosterone is
Anne Truong:anabolic, it actually increases muscle mass and decreases body
Anne Truong:fat. So very important that if. You can use these together.
Anne Truong:They're very synergistic. I'm not saying I mean treating a man
Anne Truong:who has a normal testosterone level will not help putting him
Anne Truong:on more testosterone. But in most cases, I would say in most
Anne Truong:cases, but typically, I say that these medications, the GLP1 and
Anne Truong:testosterone, are very effective together.
Anne Truong:So you feel that most men and women after the age
Anne Truong:of maybe 50 to 55, when the testosterone level dropped for
Anne Truong:women and men that they should be on a hormone replacement
Anne Truong:therapy?
Anne Truong:Dr. Mohit Khera: If they're symptomatic. Well, party lines
Anne Truong:if they're symptomatic but I would say that I do think that
Anne Truong:there is beneficial effects beyond just being symptomatic.
Anne Truong:For example, testosterone is one of the best markers of overall
Anne Truong:health. If a man has low testosterone, we know that he's
Anne Truong:at a higher risk of having a heart attack, non-negotiable.
Anne Truong:Increases risk for MI. Low testosterone increases risk
Anne Truong:demands for diabetes and obesity, non-negotiable.
Anne Truong:Increases his risk for bone and bone fracture. We know that
Anne Truong:osteopenia and osteoporosis significantly go up in these
Anne Truong:patients. We also know that low test also increases the risk for
Anne Truong:depression. It was my study significant increases for
Anne Truong:depression. So forget sex. I told you if I had a blood test
Anne Truong:that I could order that would give you a window to your heart,
Anne Truong:to depression, to diabetes, obesity, bone fracture. We know
Anne Truong:that low test also has been associated with prostate cancer
Anne Truong:risk as well. You show me in another blood test I can get
Anne Truong:that's a better marker of men's overall health. It's not TSH,
Anne Truong:it's not lipids, it's not C reactive proteins, it's not your
Anne Truong:gas, doctor, not a single blood test is a better marker of
Anne Truong:everything I just told you in men's health, and that blood
Anne Truong:test also gives you a window of symptoms, energy, libido,
Anne Truong:erectile function. So every man over the age of 40, I believe,
Anne Truong:should have a serum testosterone level checked annually. And we
Anne Truong:started a nonprofit. It's called the testosterone project. The
Anne Truong:testosterone project has three missions. One, increased testing
Anne Truong:for all men over the age of 40, every man. Number two, that we
Anne Truong:should actually deregulate testosterone. It's shocking to
Anne Truong:me that testosterone, and natural hormone that we make, is
Anne Truong:treated just like Vicodin, where it's regulated in the same
Anne Truong:capacity. And three, the mission of the testosterone project is
Anne Truong:to bring testosterone to women through the FDA and make it
Anne Truong:available. I mean, think about this. Testosterone has been
Anne Truong:around since 1935 so that's when it was first synthesized by moon
Anne Truong:in lucica, 1935 shortly after testosterone was used in women
Anne Truong:in the late 1930s if you and I walked into Walgreens today and
Anne Truong:said, Give me all the testosterone for men put out
Anne Truong:over 20 products sitting on top of the counter, I said, Give me
Anne Truong:all the testosterone products available for women, zero, not
Anne Truong:one. FDA approved testosterone product in for women, if we went
Anne Truong:to Australia, that would be if we went to UK, we could get a
Anne Truong:test. Also for women, not in the US, we have to improvise. We
Anne Truong:have to use the testosterone. For men, use 110th dose. We have
Anne Truong:to compound it with the cream. We have to be creative. But she
Anne Truong:can't go in. She says, Look, my husband goes in. He pays $10
Anne Truong:copay. I go in, I gotta pay full price. Why? Why do I have to pay
Anne Truong:and he doesn't. We both make testosterone. In fact, I make
Anne Truong:one makes more testosterone any woman in the body, but I have to
Anne Truong:pay full price. Why? It doesn't make any sense. And so that's
Anne Truong:one of the goals of a testosterone browser.
Anne Truong:I love that. I have to check that out as well too.
Anne Truong:But that we know there's always been a sexual disparity in
Anne Truong:research for men versus women health, like how many medication
Anne Truong:there are for ED versus how many medication there are for female
Anne Truong:sexual dysfunction.
Anne Truong:Dr. Mohit Khera: I want to give you an example of that. So Anne,
Anne Truong:remember this for many years, if in 2014 if you went again to
Anne Truong:Walgreen, just said, Give me all the sexual dysfunction drugs for
Anne Truong:men, over 30 drugs. In 2014 we had zero approved for women. It
Anne Truong:wasn't till 2015 when flibanserin got first FDA
Anne Truong:approved, the first drug for women ever, for FSD. Then it
Anne Truong:came out till 2015 several years later, we had Vyleesi, which
Anne Truong:came out, and then we have two. But can you imagine the amount
Anne Truong:of research that we have devoted to female sexual dysfunction?
Anne Truong:It's just a fraction. And the amount of treatment options we
Anne Truong:have for women is just a fraction of what we have for
Anne Truong:men, which is unfortunate, because, as I mentioned earlier,
Anne Truong:up to 48% of women, the US suffer from this condition. And
Anne Truong:now I turn around and say, I don't have much to offer. I
Anne Truong:mean, fortunately, we have starting to see some traction,
Anne Truong:but we need more research.
Anne Truong:So when you say 48%, is that all from over 40 or
Anne Truong:just across anything over?
Anne Truong:Dr. Mohit Khera: I think, I believe it was over 40. The
Anne Truong:studies showed 40. I forgot the cut off age where he started. To
Anne Truong:be honest with you.
Anne Truong:Yeah, I think it's over 40. Yeah, we've heard that
Anne Truong:around 50% it's probably an underestimate actually, because
Anne Truong:that study with a long time ago.
Anne Truong:Dr. Mohit Khera: But I do think that it's underestimate. I think
Anne Truong:many women who suffer from FSD don't talk about it. I mean,
Anne Truong:there's a stigma about sexual dysfunction. I give you an
Anne Truong:example. I was giving a lecture, and I said to everyone in the
Anne Truong:crowd, can you raise your hand if. You suffer from
Anne Truong:hypertension, and actually quite a hand. Few hands went up. Then
Anne Truong:I asked, Can you raise your hand if you have sexual dysfunction?
Anne Truong:Almost no. One hand went up. It was a woman. One hand, okay. And
Anne Truong:you know very well statistically that that's not true, because up
Anne Truong:to 48% of women will have FSD. And we know if you look at the
Anne Truong:men's statistics, 40% of men have ed at 40, 50% at 50, 60% at
Anne Truong:60, 70% at 70, 100% at 100. It's one of the most prevalent
Anne Truong:conditions out there. But we will not raise our hand for
Anne Truong:sexual dysfunction. We have no problem raising our hand for
Anne Truong:hypertension. We have to destigmatize it's okay to have
Anne Truong:sexual dysfunction. It's a normal part of aging. It's okay.
Anne Truong:Now there's ways to mitigate that and change it, but it's
Anne Truong:Shouldn't it be destigmatized. You should not be embarrassed.
Anne Truong:I love that. So it's okay to have sexual
Anne Truong:dysfunction. It doesn't mean you're less of a woman or less
Anne Truong:of a man. And as we work in sexual health, they always
Anne Truong:think, Oh, my God, it's like cancer, but it's as it's part of
Anne Truong:aging, but definitely can be managed like diabetes or
Anne Truong:obesity. It can be managed almost the same way it has a
Anne Truong:heart condition, right?
Anne Truong:Dr. Mohit Khera: So think about this, if a 60 year old man comes
Anne Truong:into me and says, I cannot believe I have erectile
Anne Truong:dysfunction, what's going on? I say, did you know you're the
Anne Truong:minority? Do you know that 60% of men at 60 actually have
Anne Truong:erectile dysfunction. More men that your age have it than do
Anne Truong:not. And then they sit there and say, oh, and actually feel
Anne Truong:better. They realize I'm not alone. Many people suffer from
Anne Truong:this condition, and it's not unique to me, and I think that's
Anne Truong:very important. We didn't talk about something very important.
Anne Truong:You know, sexual dysfunction is one of the best barometers of a
Anne Truong:man's overall health, that if a man gets erectile dysfunction
Anne Truong:today, you know that 15% will have a heart attack or a stroke
Anne Truong:within seven years, 15% many people have also shown that if a
Anne Truong:man has ED today, he's much more likely to get diabetes, almost
Anne Truong:two times likely to get diabetes than a man who does not ED is
Anne Truong:increased risk for not only heart attack and stroke, but
Anne Truong:increased mortality. Men with ED are much more likely to die, 25%
Anne Truong:increased risk if they have ED today. So it is a window of not
Anne Truong:only cardiovascular risk, mortality, diabetes, also
Anne Truong:depression and anxiety. So it's not just this erectile
Anne Truong:dysfunction. He's trying to tell you that something's going to
Anne Truong:come in the future, and we need to talk about it and take care
Anne Truong:I love that. And not a lot of doctors are aware
Anne Truong:of it now.
Anne Truong:of the different treatment for ED other than Hey, they go and
Anne Truong:talk to their primary care doctor, they give them Viagra,
Anne Truong:and some don't even do blood work or look at their hormones
Anne Truong:or even assess whether it's psychological or not. They're
Anne Truong:either on the ED meds and then progressive tri mix as well,
Anne Truong:without really looking at the other lifestyle factors that are
Anne Truong:important that we talk about. And as you know, is just take
Anne Truong:extra training. My daughter right now is in medical school.
Anne Truong:She's in third year medical school here in Virginia, and I'm
Anne Truong:just flabbergasted at the amount of education they're even
Anne Truong:getting now we're talking about 2024, 2025 she did her third
Anne Truong:year, about to become a doctor in about a year, nothing been
Anne Truong:taught, even in the first and second year about hormones and
Anne Truong:hormone replacement therapy or even preventative therapy.
Anne Truong:They're being taught almost the same thing that I had one I was
Anne Truong:in med school from '89 to '93 It is astonishing that there is
Anne Truong:nothing on hormone replacement therapy. She's rotating through
Anne Truong:her OB, and she's about to do urology during the OB. Nothing
Anne Truong:on hormone replacement therapy for women, or even sexual
Anne Truong:dysfunction discussion, even in her clinical rotation, and we
Anne Truong:have to learn all that post residency or even post
Anne Truong:fellowship. Have there been changes in curriculum in Baylor
Anne Truong:about that at all.
Anne Truong:Dr. Mohit Khera: Yes. So you know you're absolutely correct.
Anne Truong:Very few medical schools teach sexual dysfunction. Very few
Anne Truong:people get their training even in residency with sexual
Anne Truong:dysfunction hormones. Most of the time, you know, where they
Anne Truong:learn it, they learn it from podcasts. They learn from
Anne Truong:meetings, CME meetings that we put on. You've been to one. We
Anne Truong:talked about this in Orlando. I mean, there are meetings that
Anne Truong:you'll get that's where they get their education from. It's not
Anne Truong:during their true medical education training. Now I'm
Anne Truong:going to talk about an organization called the Sexual
Anne Truong:Medicine Society of North America, by far the best
Anne Truong:organization on the planet. I would say, when it comes to
Anne Truong:sexual medicine and education. And the Sexual Medicine Society
Anne Truong:of North America has now started a new initiative to
Anne Truong:significantly increase medical school education in sexual
Anne Truong:medicine in all 50 states, and so basically, help support it.
Anne Truong:Have champions located in medical centers in all 50
Anne Truong:states, and those champions will have monthly meetings. We
Anne Truong:currently are doing this already, and we meet with the
Anne Truong:medical students, and we teach them sexual medicine once a
Anne Truong:month. We've been doing it at Baylor now for three years. Once
Anne Truong:a month, every month, we meet with all the medical students
Anne Truong:who are interested. They come, we have some dinner, and we talk
Anne Truong:about sexual medicine. Ours. These are called rigs, regional
Anne Truong:interest groups. And so we're trying to significantly increase
Anne Truong:medical school education, because I think it starts in
Anne Truong:medical school. It's even because that's when better than
Anne Truong:even going getting ready to teach it in medical school. Make
Anne Truong:it a true curriculum, and we're actually helping the SMS and A
Anne Truong:is helping develop the curriculum for those medical
Anne Truong:schools.
Anne Truong:Oh, that's wonderful. I am really glad to
Anne Truong:hear that. And you're still the chairman?
Anne Truong:Dr. Mohit Khera: I just finished my presidency. So I just
Anne Truong:finished my presidency of the SMS and A.
Anne Truong:Gotcha. And I'm proud to say that I'm also a
Anne Truong:member as well of this association. I love the blog
Anne Truong:that you guys published, and I love that initiative, and I
Anne Truong:wanted to share that. So I want to touch upon what is your
Anne Truong:approach on the psychogenic ED component, because that is
Anne Truong:really intertwined with physical ED. You have physical ED, you
Anne Truong:don't have psychological ED, and they're kind of almost
Anne Truong:interchangeable, and I find it sometimes that it's more
Anne Truong:challenging to address the psychological component, because
Anne Truong:it just not involves the man, but also their partner as well.
Anne Truong:So what is your approach on that?
Anne Truong:Dr. Mohit Khera: So I think let's take a step back and look
Anne Truong:at exactly what's happening in this situation. Let's say a man
Anne Truong:has erectile dysfunction just once. Maybe he drank too much
Anne Truong:that night, or he just had erectile dysfunction when he
Anne Truong:engages in sexual activity. The next time, many men are saying,
Anne Truong:I hope I don't get erectile dysfunction again while they're
Anne Truong:having sex, as they say that they're fixated on not getting
Anne Truong:erectile dysfunction, they're going to get erectile
Anne Truong:dysfunction. In other words, they're more consumed then
Anne Truong:they'd have sex again. And now say, Look, I've had it twice.
Anne Truong:Sex now becomes anxiety provoking. They start getting
Anne Truong:nervous when they say, they say, I hope it doesn't happen. So I
Anne Truong:call it the vicious cycle. More sex they have, and the more ED
Anne Truong:they have, the more ED they're going to have. It just kind of
Anne Truong:gets into their head. So what you have to do is ask them
Anne Truong:certain questions. First of all, they say, with masturbation, do
Anne Truong:you have any problems? No, okay, that's psychogenic. If you get
Anne Truong:up in the morning, you wake up, do you have more strong morning
Anne Truong:erections? Yes, then that's psychogenic. It means the
Anne Truong:hardware is working fine. Everything is working fine. It
Anne Truong:just doesn't work well when you're with your partner. That
Anne Truong:is psychogenic ED. So a person who has true ED would not be
Anne Truong:able to get great erections with masturbation or wake up with
Anne Truong:morning erections because the erections don't work. So we
Anne Truong:that's very important. What's my favorite way to break
Anne Truong:psychogenic ED? My favorite way to break psychogenic ED is daily
Anne Truong:Cialis. When I give a man daily Cialis, many of these men will
Anne Truong:start waking up with morning erections, and when they engage
Anne Truong:in sexual activity, many of them don't need to take a pill. They
Anne Truong:just have sex. When they want to have sex, they feel normal
Anne Truong:again. When they feel normal again. And every time they
Anne Truong:notice, hey, past 10 times I had sex, everything was great. I had
Anne Truong:no ED. Then I start taking back the Cialis, little by little.
Anne Truong:You can take it every other day, then you can take it to twice a
Anne Truong:week, and you can stop. Many men don't want to stop the Cialis.
Anne Truong:And I think Cialis is a fantastic medication. It's FDA
Anne Truong:approved for ED, FDA approved for BPH, FDA approved for
Anne Truong:pulmonary hypertension that protects the lining of the blood
Anne Truong:vessels, protects the endothelium. It's a win, win,
Anne Truong:win on all three. So I really recommend those, particularly
Anne Truong:for the men over the age of 50. So I think that psychogenic ED
Anne Truong:can be broken with that kind of showing them everything's fine.
Anne Truong:You make a referral to a sex therapist. Most of them will not
Anne Truong:see the sex therapist, but they does help seeing a sex therapist
Anne Truong:and getting a penile ultrasound and showing them that everything
Anne Truong:is perfect, actually, is very therapeutic to them as well. Oh,
Anne Truong:look, Mr. Smith, your peak systolic was 40. Was fantastic.
Anne Truong:Your end diastolic was only two. You have very healthy blood
Anne Truong:vessels and penis. They feel better. They actually feel
Anne Truong:better knowing that everything is fine.
Anne Truong:I love that, and I actually do that a lot. I've
Anne Truong:learned, you know, ultrasound from the urology here, and it's
Anne Truong:the best thing you can do, because it's objective evidence
Anne Truong:that, hey, everything is working. The plumbing is working
Anne Truong:really, really well. And so what dose?
Anne Truong:Dr. Mohit Khera: the quality of the relationship? Though, that's
Anne Truong:really important. The quality of the relationship. I don't care
Anne Truong:how much medication I give you, if the quality of the
Anne Truong:relationship is poor, it will have a big impact, and not
Anne Truong:knowing that piece of information will make it more
Anne Truong:difficult to treat that patient.
Anne Truong:Well, let's say the quality is poor. As the doctor,
Anne Truong:what can you do about it?
Anne Truong:Dr. Mohit Khera: We have three phenomenal sex therapists that
Anne Truong:we use, and actually they're different ages and they have
Anne Truong:different personalities, so I kind of tailor my referral to
Anne Truong:that right person I think will suit the best for that with that
Anne Truong:sex therapist. They're all amazing, but I do think that
Anne Truong:seeking sex therapy would be important. I think also making
Anne Truong:sure that the partner does not suffer from FSD was some of the
Anne Truong:reasons that could impair the quality relationship is if the
Anne Truong:male partner is constantly wanting to engage in sexual
Anne Truong:activity and putting pressure when she does not want to engage
Anne Truong:in sexual activity, that can make it very challenging. So you
Anne Truong:have to take a deeper dive when on her and find out what's going
Anne Truong:on, and vice versa when I'm treating the female patient,
Anne Truong:that it's very important and libido is actually, is
Anne Truong:interesting. Don't forget about what I teach the residents
Anne Truong:called PETT. PETT stands for prolactin, estradiol, thyroid
Anne Truong:and testosterone. Check the PETT on anyone who has low libido,
Anne Truong:because those could be off.
Anne Truong:So PETT? So check that testosterone, thyroid,
Anne Truong:estrogen, that's right.
Anne Truong:Dr. Mohit Khera: All very important when you talk about
Anne Truong:libido and sexual orgasm function as well.
Anne Truong:That's exactly what I check too. So often time we
Anne Truong:see men, they come in and the only thing that's checked is
Anne Truong:total testosterone. That's it. No SHBG, which stands for sex
Anne Truong:hormone binding globulin or estradiol, anything like that.
Anne Truong:It's the whole picture. Testosterone, if you're
Anne Truong:listening to this men, the total testosterone alone isn'y going
Anne Truong:to tell you the whole picture, what's going on in the body.
Anne Truong:I hope you enjoyed the episode. I know it's long, but it's
Anne Truong:packed with great information. Let me know how you think about
Anne Truong:it. I love to hear from you. I would appreciate it if you
Anne Truong:subscribe, hit the notification button and share it with
Anne Truong:somebody you know that can benefit from this, because you
Anne Truong:may help somebody without even knowing about it. And also, do
Anne Truong:not suffer with ED. Do not suffer in silence. There are
Anne Truong:solutions out there, so check out the Modern Man Club. It's a
Anne Truong:space where I share information on how to get out of ED and for
Anne Truong:you to regain sexual confidence again. And together, you can get
Anne Truong:out of ED and have solution for sexual confidence. So check it
Anne Truong:out at noedman.com I hope to see you in there, and I will see you
Anne Truong:in the next episode.