Anne Truong:

This podcast is for you, the Modern Man. I'm Dr Anne

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Truong, your host. I'm an intimate health medical doctor

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and best selling author of the book, Erectile Dysfunction Fix.

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I'll do a deep dive into sexual health and performance and how

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it affects men of all ages and backgrounds. So let's get

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started, and be sure to visit my website at

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sexualhealthformmenpodcast.com for more information and

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resources from the show. See you on the inside.

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Men, are you struggling with ED? In this episode, I'm having a

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unique conversation with Dr. Mohit Khera from Baylor College

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of Medicine, a world renowned urologist and an expert in

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erectile dysfunction. He will share his perspective on

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treatment for erectile dysfunction and discover how you

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can regain your confidence and your sexual vitality again. You

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do not have to live with ED. So stay tuned for this whole

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episode. I will guarantee, you will learn something powerful.

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Hello there, modern man. In today's episode, we have one of

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the best urologists in the country, Dr. Mohit Khera,

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because I have been admiring his work for years, and we both

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graduated from the same program. So Dr. Mohit Khera is the

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professor in Department of Urology at Baylor College of

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Medicine, and holds the F. Brantley Scott Chair at urology,

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we'll dive into what that means, and he has published hundreds of

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research papers on men's sexual health, and is really the

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leading researcher and clinician in men's sexual health. I am so

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honored to have him here today in our episode. So welcome, Dr

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Khera.

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Dr. Mohit Khera: Thank you so much for having me on the show.

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Okay, so I'm gonna ask you some questions that I

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wanted you to share from your perspective. What is the latest

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in men's health at this time? What's working? What we're

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finding out that may not work? Because I know you on the cusp

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of research and about to do great research coming up, and

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I'm going to be following you and as listener, follow him,

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because he is the best in what he does in male sexual health.

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Dr. Mohit Khera: Thank you. That's a loaded question,

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because there's so much innovation and change going on

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in men's health and sexual health as we speak right now.

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But I think the biggest thing for me is this full paradigm

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shift from being proactive and reactive historically, when in

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sexual dysfunction, we've been very reactive. We wait till the

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man gets erectile dysfunction. He comes into my office, I give

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him Viagra, and he goes on his way. That is reactive. And what

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we're now seeing is we're changing the paradigm. We're

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being proactive. We're preventing the erectile

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dysfunction from happening in the first place, and how do we

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do that? Diet, exercise, sleep, stress reduction. People are

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becoming much more aware of their bodies and preventing it.

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They're taking more care into their hormone profiles, looking

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at their testosterone level, women, for example, their

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estrogen, testosterone, progesterone, and we're also

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focusing on regenerative therapies. I know we talked

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about that earlier, just about stem cells and PRP and shock

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wave. And now we're looking into new things such as radio

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frequency, potentially hyperbaric oxygen. So there's a

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lot of new things on the horizon. But I think the biggest

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thing for me, and I think the most interesting, is this

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paradigm shift of shifting from, let me just give you Viagra. I'm

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actually going to give you a treatment like diet exercise,

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sleep and stress reduction.

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Wow. So that's a loaded question. What does that

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mean? Can you clarify diet, exercise, sleep and stress

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reduction, so our listener can have an idea what really that

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mean?

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Dr. Mohit Khera: Yeah, let's take a step back. If you look at

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all the podcasts that we're listening to today. You're going

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to hear two big buzz words. The first word is lifespan. The

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second one is health span. You hear health span and lifespan

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over and over again. And so Anne, you and I both want our

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health span to last as long as our lifespan. I don't want to

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live till 80, but only be healthy till 60. That would not

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be good for me. Well, interestingly, most people think

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about their sex ban. Your sex band is the portion of your life

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where you'll be able to engage in satisfying sexual activity.

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We, most of us, want our sex band to last as long as our

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lifespan, and so that's very important. And so how do you do.

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Diet? Well, many of the techniques that you're hearing

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online and hearing on these podcasts of how to improve your

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health span is are the same things that improve your sex

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span. So when I talk about diet, diets that typically are anti

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inflammatory, that have high antioxidants, a low glycemic

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index, typically have more impact on improving sexual

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function. The one that's quoted the most is the Mediterranean

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diet. We have the most data on the Mediterranean diet for

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sexual dysfunction. Now, I don't think the Mediterranean diets

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right for everybody, and I think what's unique about the

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Mediterranean diet is it does have it's very high

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antioxidants. It's a low inflammatory diet. We talk about

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sleep. Do you need at least seven to eight hours of sleep a

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night to help improve your sexual function. If you get less

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than six hours of sleep per night, it actually is

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detrimental to your sexual function. It can actually impair

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sexual function. Some people say, Well, Doctor, I heard, the

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more sleep I get, the better sexual function I'll have. But

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that's not exactly true. Roughly around nine hours, it plateaus.

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So sleeping 12 hours doesn't make your erections better. You

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really want to be in that sweet spot of seven to eight hours,

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and remember that it's not just the amount of hours you sleep.

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We also talk about quality of sleep, right? So you want to

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have good quality, good REM good, deep sleep. And you also

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want to mitigate sleep disorders, the number one sleep

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disorder causing sexual dysfunction in the world is

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sleep apnea. Sleep Apnea significant increases sexual

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dysfunction. The number two disorder in the world is

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insomnia. So just be careful, if you have these conditions,

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addressing those conditions can make a big difference.

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Wow. So I want to kind of circle back a little bit

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when you say, why is there a paradigm shift from reactive to

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preventative? Now, what has happened that created that?

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Dr. Mohit Khera: I think the biggest is social media and

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podcasts. People are listening to social media. They're

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listening but they had, did not have this vehicle in the past.

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And that is really important. If you look at the health podcast,

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look just like this one. Now. People are getting their

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education through you, not through the newspaper anymore,

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not through the TV anymore. They're getting their education

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through you. And what you'll see on many of these podcasts is

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they're talking about improving health, improving the quality of

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health, and being proactive about your health. Whether some

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people talk about red light therapy, they talk about

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meditation, and mindfulness. I mean, everything is about

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So I love how you use the word sex span. That's the first I've

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improving your health, and so these in effect, are actually

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improving your sex being it's the same thing. Let's take

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exercise for a second. We published a paper two years ago

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showing that exercise alone, just exercise, significantly

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reverses erectile dysfunction. In our study, we looked at 11

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meta analysis, and it was on average 40 minutes four times a

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week. That's all you gotta remember. 40 minutes four times

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a week. It's 160 minutes over a period of six months,

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significantly increased the IIEF for the erectile function

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scores. What's so interesting is the more severe the erectile

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dysfunction you had, the greater the improvements in IIEF scores,

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and that's just with exercise right now, if I tell someone to

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do 40 minutes of moderate to vigorous exercise four times a

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week, I will significantly reverse and improve their sex

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band. But guess what, Anne, I'm also going to improve their

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health. I'm also going to improve their lifespan. I mean,

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I get other benefits besides just improving their sex band.

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So I think the same principles that we use for health span and

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lifespan absolutely apply to sexpan.

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heard of it, and it's almost like, Hey, if you improve your

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sexual health, you will live longer. So that may motivate

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people to correlate both of it, because everybody want to live

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longer and be healthy and have quality of life. But what we

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find out in this view, is that it's so hard to motivate people

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to exercise.

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Yes, no, I agree, but I will tell you very interesting story.

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There was a study that came out of Saint Louis, and they were

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looking at young men, 18 to 40, and they looked at them coming

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in with a diagnosis of ED and they would screen them for

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diabetes. And what they found was that roughly 30% of the men

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who came in for a diagnosis of erectile dysfunction had

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actually pre diabetes or diabetes on diagnosis, that's a

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lot of people, 30% now I want you to think about when you and

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I were 3025, 30. We don't go see the doctor a 28 year old I'm not

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going to go in and go get my blood pressure checked. I have

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other things to do. I'm not going to go in and get my

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cholesterol, my sugar checked. But if a 28 year old man gets

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erectile dysfunction, he is the first person at my door tomorrow

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morning saying I got a problem. And why is that important?

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Because I believe that sexual dysfunction is the gateway to

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treating all the other medical conditions. If he's going to

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come in for that moment, I have a window and opportunity. Unity,

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to screen that hemoglobin A1C to look at those lipids, to see

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what else is going on with his health. And if I tell him that,

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if you improve your blood sugar, you will actually improve your

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sexual function, many men are more motivated do that than if I

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just say, Hey, you got pre diabetes. Keep an eye on it.

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Let's try to improve it, they will be more motivated to take

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care of their health. Do sexual function, and that, in a way,

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has a trickle down effect on all the other comorbidities.

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So that's going to lead me to the next two

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questions. So, since we're talking about younger men,

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what's going on? Why are we seeing younger men now with ED?

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We should see that more in the men over 60 or 50. Why? What's

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going on?

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Dr. Mohit Khera: Let's look at many different reasons why.

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We'll start with just a general statement about the population

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is becoming more unhealthy decade after decade. If I showed

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you a graph of obesity, diabetes and metabolic syndrome, a graph

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and I show you decade by decade, the percentage of men who have

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obesity, diabetes and metabolic syndrome from the ages of 18 to

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40, you're going to see it skyrocketing in the United

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States like this, and that lines in the mimic ED rates in men, as

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well as population because diabetes is the number one risk

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factor of having ED four times more likely obesity. All of

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these conditions also significantly drop serum

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testosterone levels, no question. So as I drop the serum

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testosterone level, as I become more obese, diabetes, these are

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comorbidities that will take a hit on erectile function. Number

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three is that there is now a era of social media, and what's

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happening is the porn has significantly increased, and

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when you see a significant amount of pornography. What

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happens is your expectation is far greater than your reality,

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and so that delta can cause many of these men to develop erectile

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dysfunction. So we ask them, Do you have many men? Say, look, I

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have ED. I can't get erection. I say, How about by yourself? Oh,

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no problem. Okay, then now I got the idea, if you have

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masturbation, I have no issue. How about in the morning when

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you wake up? No issue. But with my partner, I have ED, what

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they're telling you is they have psychogenic ED, and I've seen

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the rate of psychogenic ED go up, and I think it has to do

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with porn. I think it has a lot to do with social media and the

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lack of interaction we all have now, most of our interactions

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with the phone and not with other people.

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Well, not to mention now AI. I was at a

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conference, and now I'm looking at chat GPT, and you can

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converse with it. Now there's a voice chat GPT, you can converse

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with that. Even give it a name, will be as if you're talking to

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a person. So imagine that if you're at home, you can talk to

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somebody else that could you could give it a name, it's like

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you don't even have to leave the house anymore now, right?

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Dr. Mohit Khera: Right, but, but now there's a whole era of

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marketing coming out with sexual AI. In other words, you can find

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a partner online who will talk to you. And there was one study

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that I just wasn't a study. It was just a it was an article

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describing a gentleman who had fell in love with his AI bot

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wanted, and you have to pay every time you talk, and

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roughly, spend almost $2 million and trying to keep this

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conversation going and this relationship going. So I think

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it's you just gotta be careful, because I think AI and what's

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happening in the world of Sexual Medicine is going to change

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drastically.

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So what you were saying that the person was not a

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person. It was an AI you were talking to?

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Dr. Mohit Khera: Right. Fell in love with, could not stop

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talking to, was sexually attracted to, and it was, I

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believe it was, roughly $2 million astonishing number. But

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in other words, you just have to realize that these AI bots and

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the area of Sexual Medicine is growing. There are now Virtual

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Reality places that you can go into to have sexual encounters

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with AI bots as well. So it's changing our field of sexuality,

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and how we perceive sexuality. How we have sex is changing.

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So what are your views on that when we're now

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moving to virtual reality and so forth. Obviously not good,

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because we're social being, and we're taking away that touch and

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feel, that sensation. What are your views on that?

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Dr. Mohit Khera: So I'm personally against it at this

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point. I mean, I just feel that there's something important

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about the human connection. There's something important

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about being intimate with another person. It's my personal

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opinion. I think there are others that say this is great.

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You do things on your own. And personally, I do feel that it's

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important to have the human connection, keep the intimacy

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and keep that relationship going with another person. I think

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it's important.

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You just give me an idea for my next episode to talk

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about virtual reality, virtual AI, so another question was that

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you give me the scenario of a younger man who's more motivated

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because he has ED and that is a gateway for opening a gateway

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for better health for him down the road. What about I wouldn't

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say older, but a man over 5055, that has. ED. What would be your

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approach for him versus a younger male in their 20s?

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Dr. Mohit Khera: Sure, you know most of the time, the younger

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patients are more likely to have psychogenic ED, so you just want

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to be careful about asking about getting morning erections and

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masturbation. But older men typically have comorbid

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conditions that they've acquired that have now caused them to

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have erectile dysfunction. And my only wish, my only hope, was

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that I had had to had the opportunity to meet them earlier

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in life, to where I could change the trajectory so they're not

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coming to me at 55 and we could have done things earlier to

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prevent the ED from happening at that time. Maybe it would have

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been lifestyle modification, could have been hormonal, could

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be with your partner. So those are things that you think about.

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But if he comes in, obviously, I want to first look at everything

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that could be hurting his erectile function, modifiable

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risk factors. Maybe it's an SSRI, an anti androgen. Maybe

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they're on finasteride. Maybe they're on something that's

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causing them to have the ED. So you want to take away the

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enticing so whatever's causing the ED away, then you want to

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look at other modifiable risk factors. And we talked about

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this earlier, but it's lifestyle modification, diet, exercise,

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sleep, stress reduction. I want to optimize the hormones,

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particularly the testosterone level. Optimizing the

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testosterone can significantly help this patient. And then once

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you've done all that, you have to make sure you ask about the

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partner, and I'll just give you a story. When I finished my

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Wow. So what you're saying is that if you treat one

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fellowship, I was very proud of myself, and I was able to get

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these men, these amazing erections, great, livid, and

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they would go home and they would have noone have sex with,

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because their wives would say, one woman called me. She said,

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Look, things were great until he met you, and now we fight all

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the time because he wants to have sex and I don't, and we

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haven't had sex in 10 years. And now we fight all the time, and

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it's because of you. And I thought to myself, she's right.

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I mean, either leave both libidos low or leave put both

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libidos high, but you never put one high and one low, right?

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That's a big mistake. And so very quickly that year, I flew

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out, I spent some time with Erwin Goldstein, who's the god

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bother of female sexual dysfunction. Went a lot of his

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courses at ish wish. And for 6017, years now, I've been

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treating women. Because by treating the woman, I'm actually

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treating the man. By treating the man, I'm actually treating

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the woman. The best examples I can give you. And have you and

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have you seen this over and over again? Erwin Goldstein did a

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study with Levitra. He took men and he gave half the men

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Levitra, Half the men placebo. He said, I don't want to meet

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your female partner, but can you give her this questionnaire at

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the beginning and the end of the study? It's called the fsfi

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female sexual function index, most commonly used. He gave the

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questioner to all the women at home, what he found was that

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those men who had the Vitra had an improvement in the rectal

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function. Those women at home also had a significant

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improvement in their female sexual function, meaning

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arousal, libido, orgasmic function, and those men who got

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placebo, those women, saw no improvements in their sexual

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function. So think about this, and I am actually treating a

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woman by just treating the male partner, I'm seeing significant

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improvements, just like I'd see if I gave her a pill or I gave

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her testosterone. And we did studies showing the opposite. If

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I treat her and I skyrocket her libido. Guess what happens? His

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erection is improved, so it's linked. You can't just treat one

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person without addressing the other person at home.

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partner, the other partner will also improve, even though you're

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not directly treating their spouse or significant other.

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Dr. Mohit Khera: Absolutely. Absolutely well documented, well

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shown. So when I treat that male partner in my office or that

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female partner in my office, I know that the sexual function of

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the other partner at home will improve. The problem is, is that

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we have to actually address what's going on like the biggest

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mistake you can do is give the man via Go and tell me the home

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not even ask about the female partner. What if this partner

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does not want to have sex? What if this partner is there's an

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issue, there's something you want to address them both as a

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couple, if you want to improve the efficacy of that whole

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relationship, giving him Viagra and telling him to go is not the

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solution. You need to say, Tell me about your partner. Is she

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post menopausal? Does she have pain with intercourse? Anyone

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who has pain is going to avoid the activity the house or

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libido. Any issue with arousal? Has there any issues with

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orgasmic dysfunction? How is the quality of the relationship? Oh,

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have you seen my sex therapist? She's amazing. So there's things

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you can do to make that much better, but the handing the

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Viagra and saying goodbye is a mistake.

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I love that, and I encountered this a lot, where

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we'll treat the men and their functioning, but the women who

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are maybe in their 50s or 60s, or going to menopause and 10,

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you know, we're done. We have kids out of the house. We're

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done. I'm not interested in sex anymore. How do you address that

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scenario?

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Dr. Mohit Khera: So it depends on what the problem is. Let's

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define what female sexual dysfunction is. FSD has four.

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Components, decrease libido, decrease arousal, orgasmic

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dysfunction, or pain within a horse. If you have one of these

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four, and you're bothered by the condition, you suffer from FSD.

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So if a woman comes in and says, I have low libido, but I really

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don't care, not bothered by it, I say, okay, then you don't

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suffer from FSD. How many women in the United States suffer from

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FSD, 43 to 48% that is a lot of women. 43 to 48% how many of

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those women actually get therapy? Less than 9% so that is

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a big population of women that are suffering in silence. I call

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that suffering in silence. Many of them say, I don't know where

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to go. Many of them, when they go to their OB GYN say they

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don't want to treat it, they don't treat FSD, and so they

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just try to find ways to get cures for this problem. And it's

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actually very sad there should be better resources. The other

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problem is, there's very minimal research in FSD. We have a lot

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more research in ED, erectile dysfunction, but the amount of

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money that we spend on FSD is a fraction of what we spend in

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men, but in either case, if she has those symptoms, then we try

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to figure out what is the best way to address it. I think that

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looking at the triangle is very important. For me. The triangle

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is estrogen, progesterone and testosterone. Most people only

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look at estrogen, progesterone, you have to look at testosterone

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in women. Is extremely important. It's the number one

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driver for sexual desire in women, even more than estrogen.

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In fact, a woman makes more testosterone in her body than

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she does estrogen. So we have to look at the triangle. We look at

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the outside triangle, which is cortisol. We look at that

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thyroid, which is very important, a growth hormone, any

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other outside hormones that we can look at are very important.

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And then don't forget, I think I tell the woman, this is a 5050,

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you're going to help me with diet, exercise, sleep and

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stress. Most women I can see start doing some exercise. They

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do some change your diet. It's the sleep and stress in women

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that I see take a big hit. And if a woman is fatigued, let's

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say she's exhausted. It's 10 o'clock at night and she has a

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choice between sex and sleeping, she's most likely to sleep. I'm

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just going to tell you right now, a man, he still makes you

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sex, even if he's tired, but a woman is typically going to say

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and especially on stress. Think about this, many men use sex to

Anne Truong:

relieve their stress. That's a common thing. Many men use sex

Anne Truong:

because women typically have to relieve their stress in order to

Anne Truong:

have sex. It's kind of the opposite. And I tell these men,

Anne Truong:

I say, Look, you want to engage in sexual activity with your

Anne Truong:

wife, take her to Hawaii, take her on a trip. Relieve her

Anne Truong:

stress, help her with anything she can, and drop her stress

Anne Truong:

level. Her desire will go up, but take her out of the

Anne Truong:

stressful environment. So again, we're different, and I think

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it's really important to understand her situation, what's

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going on, but to not address the female partner when you're

Anne Truong:

taking care of the male patient, I think, is a mistake.

Anne Truong:

And now, do you always do that? When you treat

Anne Truong:

the male you also encourage their female partner to come in

Anne Truong:

Dr. Mohit Khera: I do many times they don't, but I will go

Anne Truong:

as well.

Anne Truong:

through the same question or ask the male patient, tell me about

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her desire for sex. Tell me about arousal. Do you have any

Anne Truong:

pain within a course? How old is she? She post menopausal? She

Anne Truong:

don't any hormones? Is she on any SSRIs that's going to set

Anne Truong:

down her libido and say, I'm always willing to help. But many

Anne Truong:

women don't feel comfortable. Sometimes they say, Look, I have

Anne Truong:

a little libido, but I'm happy with it. I say, great. So that's

Anne Truong:

fine. So some couples do come in together, which is great, and

Anne Truong:

that's a great discussion. Some women come in after I see the

Anne Truong:

male, then they'll come in afterward and say, Look, my

Anne Truong:

husband told me that you may be able to help. And I say, Great,

Anne Truong:

let's talk. But when they come in, it's not just about handing

Anne Truong:

her hormones and pills like it's not just about giving her

Anne Truong:

estrogen, progesterone, handing her some testosterone, some

Anne Truong:

vaginal estrogen, and saying goodbye, we go heavy, heavy

Anne Truong:

lifestyle modification. Um, she's gotta help me with the

Anne Truong:

lifestyle modification, whether it be weight reduction. Now, I

Anne Truong:

have found one thing that's actually helped a lot of men and

Anne Truong:

women, more than even hormones and when it comes to sexual

Anne Truong:

dysfunction, and that's weight loss. You know, when a woman

Anne Truong:

loses 3040, pounds, she feels amazing. She feels like a new

Anne Truong:

person, new clothes, new outlook, self image skyrockets,

Anne Truong:

and obviously helps with the joint pain and the blood sugars

Anne Truong:

and the hypertension and the cholesterol. I mean, a lot of

Anne Truong:

other things improve as well, but we use a lot of GLP1 in the

Anne Truong:

Select population of patients, and putting him or her on the

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GLP1 has really made a difference in my practice.

Anne Truong:

So you put them on GLP one and on a hormone

Anne Truong:

replacement therapy at the same time, or use diagram, yes,

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Dr. Mohit Khera: it's synergistic. So remember this,

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and we're almost done with this. We're doing a trial now at

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Baylor, where if you give someone a GLP1 agonist, they

Anne Truong:

actually can start seeing a loss in muscle mass too.

Anne Truong:

Unfortunately, because you're decreasing your caloric intake

Anne Truong:

and the muscle mass will go down in hypogonadal patients or women

Anne Truong:

with low T if you put them on testosterone and ask them to

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lift weights, to lift muscle mass, then we don't see a

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significant decline in muscle mass, because testosterone is

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anabolic, it actually increases muscle mass and decreases body

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fat. So very important that if. You can use these together.

Anne Truong:

They're very synergistic. I'm not saying I mean treating a man

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who has a normal testosterone level will not help putting him

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on more testosterone. But in most cases, I would say in most

Anne Truong:

cases, but typically, I say that these medications, the GLP1 and

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testosterone, are very effective together.

Anne Truong:

So you feel that most men and women after the age

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of maybe 50 to 55, when the testosterone level dropped for

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women and men that they should be on a hormone replacement

Anne Truong:

therapy?

Anne Truong:

Dr. Mohit Khera: If they're symptomatic. Well, party lines

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if they're symptomatic but I would say that I do think that

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there is beneficial effects beyond just being symptomatic.

Anne Truong:

For example, testosterone is one of the best markers of overall

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health. If a man has low testosterone, we know that he's

Anne Truong:

at a higher risk of having a heart attack, non-negotiable.

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Increases risk for MI. Low testosterone increases risk

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demands for diabetes and obesity, non-negotiable.

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Increases his risk for bone and bone fracture. We know that

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osteopenia and osteoporosis significantly go up in these

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patients. We also know that low test also increases the risk for

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depression. It was my study significant increases for

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depression. So forget sex. I told you if I had a blood test

Anne Truong:

that I could order that would give you a window to your heart,

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to depression, to diabetes, obesity, bone fracture. We know

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that low test also has been associated with prostate cancer

Anne Truong:

risk as well. You show me in another blood test I can get

Anne Truong:

that's a better marker of men's overall health. It's not TSH,

Anne Truong:

it's not lipids, it's not C reactive proteins, it's not your

Anne Truong:

gas, doctor, not a single blood test is a better marker of

Anne Truong:

everything I just told you in men's health, and that blood

Anne Truong:

test also gives you a window of symptoms, energy, libido,

Anne Truong:

erectile function. So every man over the age of 40, I believe,

Anne Truong:

should have a serum testosterone level checked annually. And we

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started a nonprofit. It's called the testosterone project. The

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testosterone project has three missions. One, increased testing

Anne Truong:

for all men over the age of 40, every man. Number two, that we

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should actually deregulate testosterone. It's shocking to

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me that testosterone, and natural hormone that we make, is

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treated just like Vicodin, where it's regulated in the same

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capacity. And three, the mission of the testosterone project is

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to bring testosterone to women through the FDA and make it

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available. I mean, think about this. Testosterone has been

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around since 1935 so that's when it was first synthesized by moon

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in lucica, 1935 shortly after testosterone was used in women

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in the late 1930s if you and I walked into Walgreens today and

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said, Give me all the testosterone for men put out

Anne Truong:

over 20 products sitting on top of the counter, I said, Give me

Anne Truong:

all the testosterone products available for women, zero, not

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one. FDA approved testosterone product in for women, if we went

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to Australia, that would be if we went to UK, we could get a

Anne Truong:

test. Also for women, not in the US, we have to improvise. We

Anne Truong:

have to use the testosterone. For men, use 110th dose. We have

Anne Truong:

to compound it with the cream. We have to be creative. But she

Anne Truong:

can't go in. She says, Look, my husband goes in. He pays $10

Anne Truong:

copay. I go in, I gotta pay full price. Why? Why do I have to pay

Anne Truong:

and he doesn't. We both make testosterone. In fact, I make

Anne Truong:

one makes more testosterone any woman in the body, but I have to

Anne Truong:

pay full price. Why? It doesn't make any sense. And so that's

Anne Truong:

one of the goals of a testosterone browser.

Anne Truong:

I love that. I have to check that out as well too.

Anne Truong:

But that we know there's always been a sexual disparity in

Anne Truong:

research for men versus women health, like how many medication

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there are for ED versus how many medication there are for female

Anne Truong:

sexual dysfunction.

Anne Truong:

Dr. Mohit Khera: I want to give you an example of that. So Anne,

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remember this for many years, if in 2014 if you went again to

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Walgreen, just said, Give me all the sexual dysfunction drugs for

Anne Truong:

men, over 30 drugs. In 2014 we had zero approved for women. It

Anne Truong:

wasn't till 2015 when flibanserin got first FDA

Anne Truong:

approved, the first drug for women ever, for FSD. Then it

Anne Truong:

came out till 2015 several years later, we had Vyleesi, which

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came out, and then we have two. But can you imagine the amount

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of research that we have devoted to female sexual dysfunction?

Anne Truong:

It's just a fraction. And the amount of treatment options we

Anne Truong:

have for women is just a fraction of what we have for

Anne Truong:

men, which is unfortunate, because, as I mentioned earlier,

Anne Truong:

up to 48% of women, the US suffer from this condition. And

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now I turn around and say, I don't have much to offer. I

Anne Truong:

mean, fortunately, we have starting to see some traction,

Anne Truong:

but we need more research.

Anne Truong:

So when you say 48%, is that all from over 40 or

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just across anything over?

Anne Truong:

Dr. Mohit Khera: I think, I believe it was over 40. The

Anne Truong:

studies showed 40. I forgot the cut off age where he started. To

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be honest with you.

Anne Truong:

Yeah, I think it's over 40. Yeah, we've heard that

Anne Truong:

around 50% it's probably an underestimate actually, because

Anne Truong:

that study with a long time ago.

Anne Truong:

Dr. Mohit Khera: But I do think that it's underestimate. I think

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many women who suffer from FSD don't talk about it. I mean,

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there's a stigma about sexual dysfunction. I give you an

Anne Truong:

example. I was giving a lecture, and I said to everyone in the

Anne Truong:

crowd, can you raise your hand if. You suffer from

Anne Truong:

hypertension, and actually quite a hand. Few hands went up. Then

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I asked, Can you raise your hand if you have sexual dysfunction?

Anne Truong:

Almost no. One hand went up. It was a woman. One hand, okay. And

Anne Truong:

you know very well statistically that that's not true, because up

Anne Truong:

to 48% of women will have FSD. And we know if you look at the

Anne Truong:

men's statistics, 40% of men have ed at 40, 50% at 50, 60% at

Anne Truong:

60, 70% at 70, 100% at 100. It's one of the most prevalent

Anne Truong:

conditions out there. But we will not raise our hand for

Anne Truong:

sexual dysfunction. We have no problem raising our hand for

Anne Truong:

hypertension. We have to destigmatize it's okay to have

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sexual dysfunction. It's a normal part of aging. It's okay.

Anne Truong:

Now there's ways to mitigate that and change it, but it's

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Shouldn't it be destigmatized. You should not be embarrassed.

Anne Truong:

I love that. So it's okay to have sexual

Anne Truong:

dysfunction. It doesn't mean you're less of a woman or less

Anne Truong:

of a man. And as we work in sexual health, they always

Anne Truong:

think, Oh, my God, it's like cancer, but it's as it's part of

Anne Truong:

aging, but definitely can be managed like diabetes or

Anne Truong:

obesity. It can be managed almost the same way it has a

Anne Truong:

heart condition, right?

Anne Truong:

Dr. Mohit Khera: So think about this, if a 60 year old man comes

Anne Truong:

into me and says, I cannot believe I have erectile

Anne Truong:

dysfunction, what's going on? I say, did you know you're the

Anne Truong:

minority? Do you know that 60% of men at 60 actually have

Anne Truong:

erectile dysfunction. More men that your age have it than do

Anne Truong:

not. And then they sit there and say, oh, and actually feel

Anne Truong:

better. They realize I'm not alone. Many people suffer from

Anne Truong:

this condition, and it's not unique to me, and I think that's

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very important. We didn't talk about something very important.

Anne Truong:

You know, sexual dysfunction is one of the best barometers of a

Anne Truong:

man's overall health, that if a man gets erectile dysfunction

Anne Truong:

today, you know that 15% will have a heart attack or a stroke

Anne Truong:

within seven years, 15% many people have also shown that if a

Anne Truong:

man has ED today, he's much more likely to get diabetes, almost

Anne Truong:

two times likely to get diabetes than a man who does not ED is

Anne Truong:

increased risk for not only heart attack and stroke, but

Anne Truong:

increased mortality. Men with ED are much more likely to die, 25%

Anne Truong:

increased risk if they have ED today. So it is a window of not

Anne Truong:

only cardiovascular risk, mortality, diabetes, also

Anne Truong:

depression and anxiety. So it's not just this erectile

Anne Truong:

dysfunction. He's trying to tell you that something's going to

Anne Truong:

come in the future, and we need to talk about it and take care

Anne Truong:

I love that. And not a lot of doctors are aware

Anne Truong:

of it now.

Anne Truong:

of the different treatment for ED other than Hey, they go and

Anne Truong:

talk to their primary care doctor, they give them Viagra,

Anne Truong:

and some don't even do blood work or look at their hormones

Anne Truong:

or even assess whether it's psychological or not. They're

Anne Truong:

either on the ED meds and then progressive tri mix as well,

Anne Truong:

without really looking at the other lifestyle factors that are

Anne Truong:

important that we talk about. And as you know, is just take

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extra training. My daughter right now is in medical school.

Anne Truong:

She's in third year medical school here in Virginia, and I'm

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just flabbergasted at the amount of education they're even

Anne Truong:

getting now we're talking about 2024, 2025 she did her third

Anne Truong:

year, about to become a doctor in about a year, nothing been

Anne Truong:

taught, even in the first and second year about hormones and

Anne Truong:

hormone replacement therapy or even preventative therapy.

Anne Truong:

They're being taught almost the same thing that I had one I was

Anne Truong:

in med school from '89 to '93 It is astonishing that there is

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nothing on hormone replacement therapy. She's rotating through

Anne Truong:

her OB, and she's about to do urology during the OB. Nothing

Anne Truong:

on hormone replacement therapy for women, or even sexual

Anne Truong:

dysfunction discussion, even in her clinical rotation, and we

Anne Truong:

have to learn all that post residency or even post

Anne Truong:

fellowship. Have there been changes in curriculum in Baylor

Anne Truong:

about that at all.

Anne Truong:

Dr. Mohit Khera: Yes. So you know you're absolutely correct.

Anne Truong:

Very few medical schools teach sexual dysfunction. Very few

Anne Truong:

people get their training even in residency with sexual

Anne Truong:

dysfunction hormones. Most of the time, you know, where they

Anne Truong:

learn it, they learn it from podcasts. They learn from

Anne Truong:

meetings, CME meetings that we put on. You've been to one. We

Anne Truong:

talked about this in Orlando. I mean, there are meetings that

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you'll get that's where they get their education from. It's not

Anne Truong:

during their true medical education training. Now I'm

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going to talk about an organization called the Sexual

Anne Truong:

Medicine Society of North America, by far the best

Anne Truong:

organization on the planet. I would say, when it comes to

Anne Truong:

sexual medicine and education. And the Sexual Medicine Society

Anne Truong:

of North America has now started a new initiative to

Anne Truong:

significantly increase medical school education in sexual

Anne Truong:

medicine in all 50 states, and so basically, help support it.

Anne Truong:

Have champions located in medical centers in all 50

Anne Truong:

states, and those champions will have monthly meetings. We

Anne Truong:

currently are doing this already, and we meet with the

Anne Truong:

medical students, and we teach them sexual medicine once a

Anne Truong:

month. We've been doing it at Baylor now for three years. Once

Anne Truong:

a month, every month, we meet with all the medical students

Anne Truong:

who are interested. They come, we have some dinner, and we talk

Anne Truong:

about sexual medicine. Ours. These are called rigs, regional

Anne Truong:

interest groups. And so we're trying to significantly increase

Anne Truong:

medical school education, because I think it starts in

Anne Truong:

medical school. It's even because that's when better than

Anne Truong:

even going getting ready to teach it in medical school. Make

Anne Truong:

it a true curriculum, and we're actually helping the SMS and A

Anne Truong:

is helping develop the curriculum for those medical

Anne Truong:

schools.

Anne Truong:

Oh, that's wonderful. I am really glad to

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hear that. And you're still the chairman?

Anne Truong:

Dr. Mohit Khera: I just finished my presidency. So I just

Anne Truong:

finished my presidency of the SMS and A.

Anne Truong:

Gotcha. And I'm proud to say that I'm also a

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member as well of this association. I love the blog

Anne Truong:

that you guys published, and I love that initiative, and I

Anne Truong:

wanted to share that. So I want to touch upon what is your

Anne Truong:

approach on the psychogenic ED component, because that is

Anne Truong:

really intertwined with physical ED. You have physical ED, you

Anne Truong:

don't have psychological ED, and they're kind of almost

Anne Truong:

interchangeable, and I find it sometimes that it's more

Anne Truong:

challenging to address the psychological component, because

Anne Truong:

it just not involves the man, but also their partner as well.

Anne Truong:

So what is your approach on that?

Anne Truong:

Dr. Mohit Khera: So I think let's take a step back and look

Anne Truong:

at exactly what's happening in this situation. Let's say a man

Anne Truong:

has erectile dysfunction just once. Maybe he drank too much

Anne Truong:

that night, or he just had erectile dysfunction when he

Anne Truong:

engages in sexual activity. The next time, many men are saying,

Anne Truong:

I hope I don't get erectile dysfunction again while they're

Anne Truong:

having sex, as they say that they're fixated on not getting

Anne Truong:

erectile dysfunction, they're going to get erectile

Anne Truong:

dysfunction. In other words, they're more consumed then

Anne Truong:

they'd have sex again. And now say, Look, I've had it twice.

Anne Truong:

Sex now becomes anxiety provoking. They start getting

Anne Truong:

nervous when they say, they say, I hope it doesn't happen. So I

Anne Truong:

call it the vicious cycle. More sex they have, and the more ED

Anne Truong:

they have, the more ED they're going to have. It just kind of

Anne Truong:

gets into their head. So what you have to do is ask them

Anne Truong:

certain questions. First of all, they say, with masturbation, do

Anne Truong:

you have any problems? No, okay, that's psychogenic. If you get

Anne Truong:

up in the morning, you wake up, do you have more strong morning

Anne Truong:

erections? Yes, then that's psychogenic. It means the

Anne Truong:

hardware is working fine. Everything is working fine. It

Anne Truong:

just doesn't work well when you're with your partner. That

Anne Truong:

is psychogenic ED. So a person who has true ED would not be

Anne Truong:

able to get great erections with masturbation or wake up with

Anne Truong:

morning erections because the erections don't work. So we

Anne Truong:

that's very important. What's my favorite way to break

Anne Truong:

psychogenic ED? My favorite way to break psychogenic ED is daily

Anne Truong:

Cialis. When I give a man daily Cialis, many of these men will

Anne Truong:

start waking up with morning erections, and when they engage

Anne Truong:

in sexual activity, many of them don't need to take a pill. They

Anne Truong:

just have sex. When they want to have sex, they feel normal

Anne Truong:

again. When they feel normal again. And every time they

Anne Truong:

notice, hey, past 10 times I had sex, everything was great. I had

Anne Truong:

no ED. Then I start taking back the Cialis, little by little.

Anne Truong:

You can take it every other day, then you can take it to twice a

Anne Truong:

week, and you can stop. Many men don't want to stop the Cialis.

Anne Truong:

And I think Cialis is a fantastic medication. It's FDA

Anne Truong:

approved for ED, FDA approved for BPH, FDA approved for

Anne Truong:

pulmonary hypertension that protects the lining of the blood

Anne Truong:

vessels, protects the endothelium. It's a win, win,

Anne Truong:

win on all three. So I really recommend those, particularly

Anne Truong:

for the men over the age of 50. So I think that psychogenic ED

Anne Truong:

can be broken with that kind of showing them everything's fine.

Anne Truong:

You make a referral to a sex therapist. Most of them will not

Anne Truong:

see the sex therapist, but they does help seeing a sex therapist

Anne Truong:

and getting a penile ultrasound and showing them that everything

Anne Truong:

is perfect, actually, is very therapeutic to them as well. Oh,

Anne Truong:

look, Mr. Smith, your peak systolic was 40. Was fantastic.

Anne Truong:

Your end diastolic was only two. You have very healthy blood

Anne Truong:

vessels and penis. They feel better. They actually feel

Anne Truong:

better knowing that everything is fine.

Anne Truong:

I love that, and I actually do that a lot. I've

Anne Truong:

learned, you know, ultrasound from the urology here, and it's

Anne Truong:

the best thing you can do, because it's objective evidence

Anne Truong:

that, hey, everything is working. The plumbing is working

Anne Truong:

really, really well. And so what dose?

Anne Truong:

Dr. Mohit Khera: the quality of the relationship? Though, that's

Anne Truong:

really important. The quality of the relationship. I don't care

Anne Truong:

how much medication I give you, if the quality of the

Anne Truong:

relationship is poor, it will have a big impact, and not

Anne Truong:

knowing that piece of information will make it more

Anne Truong:

difficult to treat that patient.

Anne Truong:

Well, let's say the quality is poor. As the doctor,

Anne Truong:

what can you do about it?

Anne Truong:

Dr. Mohit Khera: We have three phenomenal sex therapists that

Anne Truong:

we use, and actually they're different ages and they have

Anne Truong:

different personalities, so I kind of tailor my referral to

Anne Truong:

that right person I think will suit the best for that with that

Anne Truong:

sex therapist. They're all amazing, but I do think that

Anne Truong:

seeking sex therapy would be important. I think also making

Anne Truong:

sure that the partner does not suffer from FSD was some of the

Anne Truong:

reasons that could impair the quality relationship is if the

Anne Truong:

male partner is constantly wanting to engage in sexual

Anne Truong:

activity and putting pressure when she does not want to engage

Anne Truong:

in sexual activity, that can make it very challenging. So you

Anne Truong:

have to take a deeper dive when on her and find out what's going

Anne Truong:

on, and vice versa when I'm treating the female patient,

Anne Truong:

that it's very important and libido is actually, is

Anne Truong:

interesting. Don't forget about what I teach the residents

Anne Truong:

called PETT. PETT stands for prolactin, estradiol, thyroid

Anne Truong:

and testosterone. Check the PETT on anyone who has low libido,

Anne Truong:

because those could be off.

Anne Truong:

So PETT? So check that testosterone, thyroid,

Anne Truong:

estrogen, that's right.

Anne Truong:

Dr. Mohit Khera: All very important when you talk about

Anne Truong:

libido and sexual orgasm function as well.

Anne Truong:

That's exactly what I check too. So often time we

Anne Truong:

see men, they come in and the only thing that's checked is

Anne Truong:

total testosterone. That's it. No SHBG, which stands for sex

Anne Truong:

hormone binding globulin or estradiol, anything like that.

Anne Truong:

It's the whole picture. Testosterone, if you're

Anne Truong:

listening to this men, the total testosterone alone isn'y going

Anne Truong:

to tell you the whole picture, what's going on in the body.

Anne Truong:

I hope you enjoyed the episode. I know it's long, but it's

Anne Truong:

packed with great information. Let me know how you think about

Anne Truong:

it. I love to hear from you. I would appreciate it if you

Anne Truong:

subscribe, hit the notification button and share it with

Anne Truong:

somebody you know that can benefit from this, because you

Anne Truong:

may help somebody without even knowing about it. And also, do

Anne Truong:

not suffer with ED. Do not suffer in silence. There are

Anne Truong:

solutions out there, so check out the Modern Man Club. It's a

Anne Truong:

space where I share information on how to get out of ED and for

Anne Truong:

you to regain sexual confidence again. And together, you can get

Anne Truong:

out of ED and have solution for sexual confidence. So check it

Anne Truong:

out at noedman.com I hope to see you in there, and I will see you

Anne Truong:

in the next episode.