Rob:

Good morning, everybody.

Rob:

Today we're joined by Marilia Shimon, a registered nutritional

Rob:

therapist specializing in gut health, specifically IBS and SIBO.

Rob:

Marilia has an interesting story, which we'll touch on shortly and hold

Rob:

certifications from both the Institute of Functional Medicine and Monash University.

Rob:

Marilia, thanks for being here.

Rob:

Can you tell us a little more about yourself and how you

Rob:

ended up in alternative GI care?

Marillia:

Thank you for having me.

Marillia:

Uh, so it was through my own health journey.

Marillia:

I was a proud owner of an iron stomach.

Marillia:

I could eat and drink whatever I wanted.

Marillia:

And indigestion was not part of my vocabulary, uh, until I had

Marillia:

an episode of food poisoning and everything changed literally overnight.

Marillia:

And I've spent good seven years jumping from doctor to doctor.

Marillia:

running all sorts of tests that all came back normal, which

Marillia:

is unfortunately very common.

Marillia:

And I just couldn't, couldn't really get to the root cause of my problem.

Marillia:

I was told that my symptoms were due to IBS, but they kept getting

Marillia:

progressively worse year after year.

Marillia:

And I was just like, how is it possible that they keep

Marillia:

getting worse if it's just IBS?

Marillia:

And by saying just IBS, I'm not underestimating the, uh, the

Marillia:

consequences of having IBS, you know, obviously it's, it's a burden.

Marillia:

It's not a, an easy condition to navigate, but my symptoms really were

Marillia:

drastically getting worse year after year.

Marillia:

So I thought there is something else to it.

Marillia:

And I realized that the food poisoning from the beginning, I understood

Marillia:

the food poisoning was the initial trigger for my digestive symptoms,

Marillia:

given I had none before that.

Marillia:

And it was then through my own research trying to connect the pieces that I

Marillia:

came across SIBO and how for poisoning a bacterial infection can lead to that,

Marillia:

uh, and then everything made sense.

Rob:

Of course.

Rob:

And how did your, uh, symptoms present initially from a, from an idea standpoint?

Rob:

Was a lot of sort of pain, distention, bloating, those sorts of things or?

Marillia:

Yeah, so lots of distention, bloating.

Marillia:

I went from being able to eat absolutely everything to not being

Marillia:

able to eat pretty much anything.

Marillia:

Whatever I ate was, was causing me problems.

Marillia:

So like multiple food intolerances, I had acid reflux, indigestion,

Marillia:

distention, all of those really terrible symptoms that unfortunately

Marillia:

a lot of people are experiencing.

Rob:

Yeah, I think that's just all too common again in society where we

Rob:

are sort of just faced with not only large levels of, uh, of toxins in

Rob:

the environment, but also just foods that trigger these, these gut issues.

Rob:

I know today we're going to be touching heavily on SIBO.

Rob:

That's our discussion point.

Rob:

But before we carry on, can we just quickly sort of break down the

Rob:

difference between IBS and SIBO?

Rob:

I think a lot of people sort of see them as one thing, but obviously,

Rob:

and to some extent they are, but there's quite a discrepancy.

Rob:

There's, could you just sort of break down the difference between them?

Marillia:

So they are both.

Marillia:

Uh, similar conditions and they can coexist.

Marillia:

Symptoms are very similar in the sense of like they have

Marillia:

bloating, abdominal distention, they can have either constipation,

Marillia:

diarrhea, or a combination of both.

Marillia:

But the main symptom to keep in mind that defers them is abdominal pain.

Marillia:

So in IBS, we must have abdominal pain in order to fit

Marillia:

the criteria of IBS diagnosis.

Marillia:

And in SIBO, we don't really have that.

Marillia:

So I would say that's the main thing to keep an eye on.

Marillia:

And, you know, with that abdominal pain comes visceral hypersensitivity, which

Marillia:

is a hallmark symptom of IBS, which means you have an overly sensitive gut.

Marillia:

So you feel, you know, what my clients usually say is like, you

Marillia:

feel like that there's another person living inside your body.

Marillia:

If that makes sense, that your gut has a life of its own, which

Marillia:

it does, obviously, but you shouldn't be feeling that 24 seven.

Marillia:

And in IBS with visceral hypersensitivity, you do have that.

Marillia:

gut brain brain gut brain connection much more highlighted.

Rob:

Okay.

Rob:

And then, uh, by extension, what is SIBO?

Rob:

How would you define SIBO?

Rob:

And if you are sitting on somebody next to a plane and they asked you what you did.

Rob:

But how would you define what SIBO is?

Marillia:

So SIBO stands for small intestinal bacterial overgrowth, and it

Marillia:

means exactly what the name suggests.

Marillia:

There is an overgrowth of bacteria in the small intestine.

Marillia:

And we shouldn't have that many bacteria in that part of the intestines because

Marillia:

that's where we break down food and there is absorption of nutrients and all.

Marillia:

So essentially, it's not an infection, it's just an overgrowth of bacteria

Marillia:

in the wrong place in the gut.

Marillia:

We should have large amounts of bacteria in the large intestine,

Marillia:

but not in the small intestine.

Rob:

Yeah, I think that's what people will often sometimes sort of refer to

Rob:

when they are talking to about dysbiosis.

Rob:

So would you almost say that SIBO is a form of dysbiosis then?

Marillia:

Yeah, some, some, uh, experts do say that it's a form of dysbiosis,

Marillia:

is a disorder of the whole GI ecosystem.

Marillia:

So I think there are different ways of, you know, explaining it.

Marillia:

But yeah, dysbiosis is definitely one of them.

Marillia:

And

Rob:

I know we'll begin on the treatment in a shortly and bear

Rob:

with me, but, uh, to just give the listener a bit more of a background,

Rob:

there are various types of SIBO.

Rob:

Can you sort of elucidate the different types and how they

Rob:

maybe present differently?

Marillia:

Yeah, of course.

Marillia:

So as of now, we know that there are three types, hydrogen dominant SIBO,

Marillia:

methane dominant and hydrogen sulfide.

Marillia:

So the hydrogen dominant one has.

Marillia:

Uh, presents the symptoms like bloating and diarrhea, or sometimes it could

Marillia:

be a bit of constipation as well.

Marillia:

The methane, it's predominantly bloating and constipation.

Marillia:

And the hydrogen sulfide is bloating and more severe diarrhea than the hydrogen.

Marillia:

So they all have bloating in common, but then it's more like,

Marillia:

is it on the constipation side?

Marillia:

Is it on the mixed side or is it on the diarrhea side?

Marillia:

Fair enough.

Rob:

And then I suppose the, the golden question is, and it's obviously a

Rob:

fairly long answer and it depends on the individual, but is there sort of

Rob:

a common cause of these conditions, these sorts of SIBO types of conditions

Rob:

in general, or are they all as unique as the individual in question?

Marillia:

Yeah, so I think the most important thing to understand

Marillia:

is that SIBO is not a root cause.

Marillia:

It's a result of impaired gut motility.

Marillia:

So as the gut slows down in the movement of the gut slows

Marillia:

down, it can allow bacteria to overgrow in the small intestine.

Marillia:

Why that happens?

Marillia:

We know that the physiological underlying causes are dysfunction of

Marillia:

the migrating motor complex, which are the cleaning waves, you know,

Marillia:

or the housekeeping of the gut.

Marillia:

And why that happens?

Marillia:

There are different reasons.

Marillia:

We know that the most common cause of MMC dysfunction is food poisoning.

Marillia:

So got a stomach bug.

Marillia:

Typical story.

Marillia:

Like mine was able to eat everything.

Marillia:

Got a stomach bug overnight.

Marillia:

Things kind of changed and then after a few months got things

Marillia:

got progressively worse and then that's because you developed SIBO.

Marillia:

But there are other, other underlying causes as well.

Marillia:

It can be structural issues, scarring from surgery, diabetes,

Marillia:

or even it could be side effect of medications that slow down the gut.

Rob:

Okay, and that being peristalsis that the MCC is affecting, is that correct?

Marillia:

Yeah, it's it's the movement.

Marillia:

It's actually affecting the MMC and like upper digestive, not just peristalsis.

Rob:

Okay, so it's sort of going from a sort of a neurological

Rob:

level all the way down to the gut.

Marillia:

Yeah, that's

Rob:

interesting that I did not know and I suppose this would be a perfect

Rob:

segue to talk about how generally you start working with patients and

Rob:

how you start treating individuals.

Rob:

There are a lot of ways of doing this, but what is your sort of main modality

Rob:

when you start talking about when you have somebody who obviously comes to you with.

Rob:

These digestive complaints, and obviously they also present, uh, in other words,

Rob:

brain fog, aching joints, a lot of very broad, non specific complaints.

Rob:

How do you go about sort of breaking that down and then working with an

Rob:

individual from, from the beginning?

Marillia:

So the most important thing always is to rule out

Marillia:

medical conditions, right?

Marillia:

That's the first thing.

Marillia:

So you want to see your GP or a specialist and rule out

Marillia:

things like Crohn's, ulcerative colitis, celiac disease and all.

Marillia:

So you've done all that.

Marillia:

That's usually the top three things that they will investigate.

Marillia:

That's all clear.

Marillia:

Most likely they will tell you then it's IBS because you know, with IBS, we don't

Marillia:

have a test, but we have that criteria that we follow tick some of the boxes.

Marillia:

Okay.

Marillia:

IBS off you go.

Marillia:

But then we know that there is more to it, right?

Marillia:

Now, we know that 30 to 80 percent of IBS can be SIBO.

Marillia:

So then next step in what I usually do is, okay, have you tested for SIBO?

Marillia:

So that's how we start.

Marillia:

Most of the time it comes back positive, but obviously you need

Marillia:

to rule out other things as well.

Marillia:

So lactose intolerance is so common, but not tested and it could be that

Marillia:

that's As simple as that, you know, you just have a lactose intolerance.

Marillia:

Are you using, uh,

Rob:

sorry to interrupt, but are you using breath testing predominantly

Rob:

to test for, for CV or various, uh, different breath tests?

Marillia:

Yes, predominantly breath test.

Marillia:

If you look at the research, that's what's being used as well.

Marillia:

So, you know, at the moment, I think that's the best tool we have.

Marillia:

So as I was saying, like, you need to think about other things like food

Marillia:

intolerances, histamine intolerance, lactose intolerance, fructose intolerance.

Marillia:

You just obviously need to correlate the symptoms.

Marillia:

But then if we have a positive, uh, SIBO breath test and they correlate with the

Marillia:

symptoms that the client is experiencing, we then need to tackle that either

Marillia:

liaising with, with their, uh, GP, you know, in, in order to get antibiotics,

Marillia:

or then we go down antimicrobial route, uh, herbal antibiotics essentially.

Rob:

Do you find, uh, slight tangent, do you find food

Rob:

sensitivity testing to be accurate?

Rob:

There, there are lots of different panels out there.

Rob:

Uh, companies like Cyrex tend to test not only IGE, but IGA as well, I believe.

Rob:

Whereas others just, and I think I've got this right, just test IGE.

Rob:

So you sort of get these false positives with a lot of food testing services.

Rob:

Uh, do you think they're effective or is ultimately just an elimination diet?

Rob:

sort of the way to go in trying to determine what food triggers

Rob:

you may or may not have.

Marillia:

Well, so we know the gold standard is the elimination diet, right?

Marillia:

So that's, that's what I do.

Marillia:

And it is.

Marillia:

It is boring, it requires commitment, patience, time, but there's no

Marillia:

other way, so that's the way I go.

Rob:

Fair enough.

Rob:

And then speaking of elimination diets, do you have a preferred one?

Rob:

Do you sort of just stick your plans purely on meat and tell them to get on

Rob:

with it, or do you just, do you remove certain potentially triggering food

Rob:

groups like FODMAPs or carbohydrates?

Rob:

Uh, what's the, sort of the lowest common denominator for you there?

Marillia:

Yeah.

Marillia:

So I'm trained on the use of the low FODMAP diet with Monash University.

Marillia:

And that's usually really what I do because there's so much scientific

Marillia:

evidence to back up the low FODMAP diet.

Marillia:

We know that up to 75 percent of individuals feel better

Marillia:

on a low FODMAP diet, but it.

Marillia:

It is a diet that requires guidance.

Marillia:

You know, it's not as simple as, okay, here's a food of a list of foods you

Marillia:

can eat and food that you cannot eat.

Marillia:

It's really not like that.

Marillia:

It's much more about portion control than yes or no.

Marillia:

Uh, so that's usually the route I take is, is the low FODMAP diet.

Rob:

Can you just explain what the low FODMAP diet is?

Rob:

I can never get the acronym right, but, uh, it is, it's basically, and

Rob:

I'll obviously get you explain it.

Rob:

Removing certain, excuse me, fermentable foods from the diet.

Rob:

Is that correct?

Marillia:

Yeah, so you're removing essentially, not removing, you're lowering

Marillia:

the intake of fermentable carbohydrates.

Marillia:

FODMAP stands for fermentable oligosaccharides, desaccharides,

Marillia:

monosaccharides, and polios.

Marillia:

And exactly, these are fermentable carbohydrates in everyone's gut.

Marillia:

But as we were talking earlier, the gut of IBS is overly sensitive.

Marillia:

So that fermentation causes a lot of discomfort, you know, in the connection

Marillia:

of the gut with the gut and the brain.

Marillia:

Uh, so you're just lowering that intake to see if symptoms get better as well.

Marillia:

And as I said, 75 percent of, of individuals do have

Marillia:

a positive result with that.

Rob:

That's interesting.

Rob:

So it's not necessarily completely removing that food, but it's, it's about

Rob:

sort of just lowering the quantity.

Rob:

Is that correct?

Marillia:

Exactly.

Marillia:

Yeah.

Marillia:

So as I said earlier, it's not about eat this, don't eat that.

Marillia:

It's about how much you're eating of those specific fault maps in the meal.

Marillia:

Uh, and if you're, you know, making sure you're not fault map stacking.

Marillia:

So for example, if you're a person that snacks a lot and you're just

Marillia:

grazing throughout the day and you're just adding those fault maps,

Marillia:

you know, on top of each other.

Marillia:

And then obviously towards the end of the day, you're super bloated, super

Marillia:

distended because you didn't have.

Marillia:

that break that your digestive system needs in order to, to break down food,

Marillia:

the food that you ate previously.

Marillia:

So it is really much about.

Marillia:

Okay.

Rob:

And then with an elimination diet, such as the FODMAP diet,

Rob:

you often have to then obviously, well, not often, you have to then

Rob:

reintroduce foods at a certain point.

Rob:

Obviously people can't just live on these diets.

Rob:

Um, well, I mean they can, but then we end up with more issues later.

Rob:

Not

Marillia:

ideal.

Marillia:

Definitely

Rob:

not.

Rob:

How are you then reintroducing foods in a patient or in an individual

Rob:

with these, with these issues?

Marillia:

Yeah.

Marillia:

So it's, it's very systematic.

Marillia:

You, um, You choose one fault map at a time.

Marillia:

So we have six fault maps.

Marillia:

You choose one at a time and then you reintroduce them

Marillia:

over a period of three days.

Marillia:

You assess symptoms day one, you're fine, you move on to portion of day two.

Marillia:

And then if you feel fine, you move on to portion of day three.

Marillia:

If at day two, you already feel that your symptoms are, are already starting to come

Marillia:

back, you then don't move on to day three and you'll find your threshold and your

Marillia:

trigger of that, of, of those fault maps.

Marillia:

So it's, it's time consuming, as I said earlier, you know, any

Marillia:

elimination diet is, you need to reintroduce step by step and then

Marillia:

find what works for you, what doesn't.

Marillia:

But if you do all of them, you know, Within eight weeks, you can get it done.

Marillia:

And I always say to my clients, if you do it, eight weeks are going to pass.

Marillia:

If you don't do it, eight weeks are going to pass.

Marillia:

So you might as well get over it.

Rob:

Yeah, of course.

Rob:

And when you're sort of reintroducing foods, do you find any sort of,

Rob:

uh, concurrent issues with maybe things like oxalates, uh, obviously

Rob:

things like a raspberries, a high in oxalates, I believe.

Rob:

Sweet potatoes as well.

Rob:

Do you ever find that when you're reintroducing Specific foods that you

Rob:

will sort of hit a a plateau where maybe there is another a food insensitivity

Rob:

That's oil not food insensitivity.

Rob:

Excuse me a plant Antinutrient in this for us in this case is causing an issue

Marillia:

I don't see that often or the one the one thing I see people react

Marillia:

the most is Fructone which is one of the fault maps And that is found in things

Marillia:

like garlic, onion, leeks, and that is by far, and the research also backs this

Marillia:

up, the one that most people react to.

Marillia:

So they may be able to reintroduce all the other FODMAPs fine, but perhaps

Marillia:

the fructan is the one that they need to kind of manage in smaller portions.

Rob:

Okay, fair enough.

Rob:

And what do you think about this cheating using FODMAPs,

Rob:

uh, FODMAP digesting enzymes?

Rob:

Uh, do you think those have a place or are they just not

Rob:

really dealing with the issue?

Marillia:

I think they have a place.

Marillia:

I mean, they, they are heavily backed by scientific evidence as well.

Marillia:

The ones that are in the market, they have their own research.

Marillia:

And I definitely think there is a place, you know, especially like if you're

Marillia:

traveling, if you're eating out and you know, you, why not have that support?

Rob:

Okay.

Rob:

So I suppose you can have your cake and eat it.

Rob:

Maybe it's not ideal all the time.

Marillia:

Yeah.

Marillia:

I mean, exactly.

Marillia:

But you don't, you don't want to be used, be using those enzymes all

Marillia:

the time because essentially you are breaking down that fiber that you want

Marillia:

to be digested by gut bacteria, right?

Marillia:

In the large intestine.

Marillia:

So if you're using that fiber every, uh, that enzyme every day, you're

Marillia:

not really getting the benefit of that, of that dietary fiber, but

Marillia:

yes, you can have the cake and eat it too in certain occasions for sure.

Rob:

And speaking of enzymes, uh, what do you think about the

Rob:

use of things like betaine HCL?

Rob:

Not necessarily only to support the digestive process, but

Rob:

also to sort of offset the development of further dysbiosis.

Rob:

Yeah.

Rob:

In conditions such as candida, quite often there is an argument to be made

Rob:

about increasing stomach acid by way of betaine HCL supplementation to sort

Rob:

of just support that digestive process and to help keep that bacteria at bay.

Rob:

Do you have any thoughts there?

Rob:

Is it something you ever use at all, perhaps?

Marillia:

Yeah.

Marillia:

I do use with, uh, especially my CBO clients a lot.

Marillia:

We know that we see, but there is, uh, an issue also with stomach acid

Marillia:

production and stomach acid is like the first line of defense, right?

Marillia:

It's everything that we're putting in our mouths is the connection of the

Marillia:

external world with our internal world.

Marillia:

So we need to have that.

Marillia:

protective barrier and the stomach acid is there to kill any, you know, opportunistic

Marillia:

bacteria, pathogens, so on and so forth.

Marillia:

So we know that we see, but we also need to support that.

Marillia:

So I do use that as part of my protocols.

Rob:

Okay.

Rob:

And one more question on digestion and I promise you we'll move on, but

Marillia:

just regarding

Rob:

histamine, obviously when There are, there's an imbalance in histamine levels.

Rob:

You're going to have higher or lower levels of stomach acid.

Rob:

I suppose one might say that by addressing the root cause of, uh,

Rob:

the SIBO you, that you would then rectify the underlying histamine issue.

Rob:

But do you ever sort of go after maybe a histamine or an MCAS issue

Rob:

directly, uh, trying to sort of lower or increase histamine levels

Rob:

to, to thereby support digestion?

Marillia:

Yeah.

Marillia:

And I see, I see his feminine tolerance a lot with, as a consequence of SIBO.

Marillia:

So it's, as you said, it's about understanding the underlying cause,

Marillia:

what it is that it's causing that.

Marillia:

And then I think you kind of need to, you need to assess what is more urgent,

Marillia:

let's say, you know, so if you have a client, if I have a client with.

Marillia:

SIBO and histamine intolerance, and the histamine intolerance seems to be the

Marillia:

thing that is driving, you know, the rashes, this, all the skin symptoms and

Marillia:

potentially also diarrhea, then I go first on a low, put them on a low histamine

Marillia:

diet to bring the symptoms, you know, calm it down, let's say, and then tackle

Marillia:

SIBO, but it is a step by step process.

Rob:

Perfect.

Rob:

Understood.

Rob:

Right.

Rob:

One more question about diet.

Rob:

And this is a selfish question because this was where my body of research

Rob:

and my academic background was in.

Rob:

But ketogenic diets, what do you think about them in terms of their ability

Rob:

to sort of maybe help to modulate the symptoms of some of these issues?

Rob:

Obviously you, you, with the ketogenic diet, you're not necessarily

Rob:

getting rid of the FODMAPs.

Rob:

But just by reducing the carbohydrate burden on the body, is that ever

Rob:

an effective strategy or is it sort of really only sort of dealing

Rob:

with one third of the problem?

Marillia:

I don't really implement the ketogenic diet simply because the research

Marillia:

shows that it's actually one of the most detrimental diets for the gut microbiome.

Marillia:

So it's not, it's not something I work with.

Marillia:

I do understand it has its place, you know, for different conditions,

Marillia:

but it's not something that I, I, I practice in my clinic.

Rob:

Okay, perfect.

Rob:

Understood.

Rob:

I'll stop preaching about that one then.

Rob:

All right, so moving on to sorts of Treatment modalities beyond just diet.

Rob:

What else are you using?

Rob:

Things like probiotics, antimicrobials, et cetera.

Marillia:

Yeah.

Marillia:

Uh, so yes, antimicrobials, definitely using that.

Marillia:

So I always discuss with my clients that they have two options, right?

Marillia:

So if we're tackling seabird, they can go down the antibiotic route, refluxamine.

Marillia:

but they can also go down the herbal supplementation.

Marillia:

So I present both, we discuss and, you know, let them decide

Marillia:

what it is that they want to do.

Marillia:

Uh, if they want to, to go down the, the herbal route, then yes, uh, using

Marillia:

a combination of of herbs, allicin, berberine, oregano oil, anine.

Marillia:

Always have a biofilm disruptor there as well.

Marillia:

Uh, and then, you know, combining those herbs for about four to six

Marillia:

weeks and, and see how symptoms get better, retest, see where we are at,

Marillia:

do we need more, what do we do next.

Rob:

And just to clarify rifampicin, rifampicin is an antibiotic that

Rob:

doesn't pass into the bloodstream.

Rob:

It just works in the gastrointestinal tract.

Rob:

Is that correct?

Marillia:

Yes.

Marillia:

So 99 percent of the absorption is in the, in the GI tract.

Marillia:

So absolutely.

Rob:

Okay.

Rob:

Um, then regarding the antimicrobials again, how are

Rob:

you recycling them specifically?

Rob:

Do you find that people become tolerant to these compounds pretty quickly?

Rob:

Uh, do you have some that you prefer?

Rob:

Um, how do you, uh, treat somebody with, well, a patient

Rob:

with, with these, uh, compounds?

Marillia:

Yeah.

Marillia:

So I find that most of them are well tolerated, apart from allicin.

Marillia:

Allicin is definitely the one that most people react to.

Marillia:

Uh, and then it's really about, okay, let's say there's an ideal.

Marillia:

that you should be taking, but you know, if that doesn't work for you

Marillia:

and it's actually giving you more symptoms than results, then you

Marillia:

need to find whatever works for you.

Marillia:

So if it is, you know, one capsule a day, or if it's the whole, the

Marillia:

full dosage, but every other day.

Marillia:

So we, we really need to work with each individual and

Marillia:

find out what works for them.

Marillia:

But I find that all the others are very well tolerated apart from the allicin.

Rob:

And the issue with allicin being the prebiotic fiber

Rob:

that then triggers the, uh,

Marillia:

Yeah.

Marillia:

Potentially.

Marillia:

Yes.

Marillia:

Oh, okay.

Marillia:

And it is, it is quite difficult to digest as well.

Marillia:

It can be a bit, it can be a bit heavy and also it depends, you know,

Marillia:

so like if you take it before a meal or after a meal that all these

Marillia:

things can also make a difference.

Rob:

Is that sort of, and allicin obviously just for

Rob:

people is garlic extract.

Rob:

Is that correct?

Rob:

It's the active ingredient in garlic.

Marillia:

Yeah, and usually the fault map is removed, you know,

Marillia:

through this process, but still some people cannot tolerate it.

Marillia:

It could be for other reasons, different compounds.

Rob:

Okay.

Rob:

And use of probiotics, specifically things like Saccharomyces boulardii?

Marillia:

Yeah, I do use it a lot.

Marillia:

I think there's a lot of, you know, as we know, there's a lot of research

Marillia:

for Trevor's diarrhea and, and the use of Saccharomyces boulardii.

Marillia:

So that is one I use.

Marillia:

I use quite often, especially when I am dealing with clients that have

Marillia:

like post infectious IBS slash SIBO.

Rob:

And other classes of probiotics, do you find that they are effective

Rob:

or do you really just sort of rely on Saccharomyces specifically?

Marillia:

Yeah, no, I do use some lactobacillus, Bifidobacteria.

Marillia:

There is also some research, you know, the research with SIBO

Marillia:

and probiotics is very limited.

Marillia:

So there's a lot that we know about IBS, but not specifically SIBO.

Marillia:

But it is also a matter of trial and error, you know, that there is the

Marillia:

research and you know what to use.

Marillia:

But again, does that work for that person?

Marillia:

Great.

Marillia:

It doesn't work.

Marillia:

Okay, let's do something else.

Marillia:

So I also use sport, sport based probiotics sometimes and I find

Marillia:

that they are very well tolerated.

Rob:

Okay, perfect.

Rob:

And when looking at probiotics, like specifically the A lot has been made

Rob:

in recent, well, definitely in recent years about working with specific species

Rob:

beyond just the strain and, and just for the listeners, probiotics are broken

Rob:

down at a high level into the genus, so sort of the, the overarching family,

Rob:

then specific species, and then specific strains, I hope we got that right, and

Rob:

for the most part, the literature that I've looked at seems to indicate that

Rob:

the species is where it's Is what you need to focus on as a clinician, but

Rob:

then you get a lot of companies that start marketing specific strains of

Rob:

specific species, uh, as being the go to.

Rob:

Do you find this to have any merit in your experience or is it again just

Rob:

work at the species level enough?

Marillia:

I think the strains, the strains level is, is becoming very predominant

Marillia:

and we'll see more and more of like, you know That specific strain that has been

Marillia:

researched for that specific thing or that one for that other thing So definitely

Marillia:

it's uh, it's something I keep in mind.

Rob:

Okay, so it is taking hold.

Rob:

That's interesting Moving on, I'd love to get some feedback.

Rob:

Well, I'd love to pick your brain about some specific questions.

Rob:

Let's call them rapid fire questions.

Marillia:

Yeah.

Rob:

Olympic system retraining.

Rob:

It's been made quite popular again in recent months or in recent, in recent

Rob:

years, programs like the Gupta method.

Rob:

I believe there are a few in the States and one in Australia called DN DNRS.

Rob:

What do you think about limbic system retraining

Rob:

specifically for, for gut issues?

Marillia:

I think it's really important.

Marillia:

We know just like the low FODMAP diet has a lot of scientific evidence.

Marillia:

There's also scientific evidence for things like yoga, meditation,

Marillia:

gut directed hypnotherapy.

Marillia:

These are all things that can help with symptoms, with GI symptoms.

Marillia:

So, you know, I mentioned before 75 percent of the individuals respond

Marillia:

to a low FODMAP diet, but then there is the other part that doesn't.

Marillia:

And then we start to consider, okay, so how about yoga, meditation, hypnotherapy,

Marillia:

all of those things can also help.

Marillia:

So they definitely have a place.

Marillia:

And, you know, it's like every health condition, that's what I believe at

Marillia:

least is a combination of factors, right?

Marillia:

That will make a difference.

Marillia:

It's not like one thing will solve the problem is, is the whole toolkit.

Rob:

Okay.

Rob:

Next one, vagal nerve stimulation.

Rob:

A lot of these devices on the market, like the Sense8 and the Apollo, I suppose

Rob:

they're working on a similar level to the limbic system retraining, but have

Rob:

you ever utilized those in your practice?

Rob:

What do you think of those?

Rob:

Okay.

Marillia:

So I do recommend to clients and I think the main reason

Marillia:

is because nowadays most of us really struggle with doing nothing, you

Marillia:

know, telling someone to sit down for 10 minutes and literally do nothing,

Marillia:

not watch TV, not scroll the phone.

Marillia:

It's, it's a challenge.

Marillia:

So I find that these devices kind of make them feel that they're

Marillia:

doing something while they're doing nothing, if that makes sense.

Marillia:

So that, that's mostly when I, I recommend, you know, if I feel that

Marillia:

the client does have some difficulty in just like relaxing and taking

Marillia:

10 minutes to switch off, I'm like, okay, how about you get this device?

Marillia:

Because at least you, you feel that, you know, you're doing something while

Marillia:

you're relaxing at the same time.

Marillia:

But other than that, I just tell them to gargle twice a day, like strong.

Marillia:

Vibrations.

Rob:

Could you just discuss what the vagus nerve is and why potentially

Rob:

it could be an issue in people with vagus nerve dysregulation could be

Rob:

an issue in people with IBS and SIBO?

Marillia:

Yeah.

Marillia:

So we know that the vagus nerve is what connects the gut and the brain, right?

Marillia:

And it's this two way communication pathway.

Marillia:

And it is.

Marillia:

This connection is so intense where the brain sends messages to the gut,

Marillia:

the gut sends messages to the brain.

Marillia:

Actually the gut sends more messages to the brain than the brain to the gut.

Marillia:

And there can be a dysfunction, like chronic stress can, can create a

Marillia:

dysfunction in this communication and then lead to digestive symptoms.

Marillia:

But also this biosis in the gut can interrupt this communication and create

Marillia:

health problems, mental health problems.

Marillia:

So things like depression and anxiety, we know that, you know, there is

Marillia:

a big correlation between a gut dysbiosis and depressive symptoms.

Marillia:

So that's where this nerve it's engages in this to in this way

Marillia:

in the communication between them

Rob:

Yeah And the way I understand it when you sort of activate the the

Rob:

vagus nerve you are activating the the parasympathetic Sympathetic branch of the

Rob:

nervous system and by doing so you start to lower levels of stress hormones like

Rob:

cortisol adrenaline all of these Chemicals in the body that drive stress that then

Rob:

drive the production of molecules such as cytokines that just increase inflammation.

Rob:

And then you get this sort of, you fall into this vicious

Rob:

cycle where the body's inflamed.

Rob:

It's, which then triggers the vagus nerve, which then triggers

Rob:

release of these chemicals.

Rob:

And it's very hard to get out of.

Rob:

And again, uh, from my view of the literature, there does seem to be some.

Rob:

It is to show that by stimulating the vagus nerve, you can help get it out of

Rob:

this loop and then allow the body to heal.

Rob:

Yeah, at a high level, that seems to be how these devices work.

Rob:

And yeah, again, there does seem to be a fair amount of clinical efficacy for them.

Marillia:

Yeah.

Marillia:

And as you said, it's about activating the parasympathetic nervous system, right?

Marillia:

And we know that that's the rest and digest and you need to be in

Marillia:

the rest and digest mode in order to be able to digest, break down

Marillia:

food properly and avoid bloating, distention and digestive symptoms.

Marillia:

So it definitely, I'm sure the devices have a place, you know,

Marillia:

and however, whatever works for the person, you know, and if the device

Marillia:

is the thing that works, why not?

Rob:

Of course.

Rob:

Next one.

Rob:

This one is probably, yeah, it's going to raise some eyebrows.

Rob:

Uh, the carnivore diets.

Rob:

Uh, do you like it?

Rob:

Do you not like it?

Marillia:

I mean, for me, it's a hard no.

Marillia:

And I, I get that, you know, I, I started eating a carnivore diet

Marillia:

and all my GI symptoms disappeared.

Marillia:

Yeah.

Marillia:

Obviously you removed the triggers, right?

Marillia:

It's as simple as that, but you didn't really, yeah, you,

Marillia:

you didn't really address the underlying cause of the problem.

Marillia:

So if you bring the foods back, you're actually potentially going

Marillia:

to feel even worse because you depleted your gut from fiber.

Marillia:

The diversity of gut bacteria is definitely lower, and then you're

Marillia:

going to be able to tolerate even less foods than, than before.

Marillia:

So it is a hard no for me.

Rob:

Fair enough.

Rob:

Another contentious topic.

Rob:

Prebiotics.

Rob:

There seems to be this divisive line in the functional GI

Rob:

community about prebiotics.

Rob:

Some practitioners swear by them, others run a mile from them.

Rob:

We sort of touched on this earlier that, uh, at least initially there

Rob:

may not be the best intervention, but what are your thoughts on prebiotics?

Marillia:

Yeah, so obviously like prebiotics are amazing because

Marillia:

they are essentially feeding our beneficial gut bacteria, right?

Marillia:

And I think the main problem why There is confusion is because we are, we are

Marillia:

talking about two different things.

Marillia:

We're talking about people that are just looking to improve their gut

Marillia:

health, but they don't have GI issues.

Marillia:

And then people that have GI issues, and the advice is just

Marillia:

not the same for these two groups.

Marillia:

Uh, if you know, like prebiotics are found in things like garlic, onions, leeks.

Marillia:

And if I tell a SIBO client or an IBS client, yeah, you know, go

Marillia:

ahead and eat garlic onion leeks.

Marillia:

they're going to feel terrible.

Marillia:

So who are we trying to help here?

Marillia:

You know, so if it's generalized good health advice, prebiotics, yes.

Marillia:

Amazing.

Marillia:

Go for it.

Marillia:

But if you have SIBO, like this is not going to be a good idea unless

Marillia:

you have dealt with the sequel.

Marillia:

So.

Marillia:

You know, the most common ones are like inulin, FOS.

Marillia:

I definitely stay away from those, depending on the profile of the client.

Marillia:

Talking about IBS, SIBO clients, then they don't usually tolerate those well.

Marillia:

But I do like PHGG, partially hydrolyzed guar gum.

Marillia:

I find it very well tolerated.

Marillia:

Uh, we know it's, uh, like low FODMAP, you know, there are even

Marillia:

some in the market that are certified low FODMAP by Monash University.

Marillia:

So I do use that a lot and actually there is one clinical trial that showed

Marillia:

that the combination of rifaximin with PHEG to be more effective than

Marillia:

rifaximin alone in eradicating SIBO.

Marillia:

So it definitely has, has its place.

Rob:

So ultimately context matters when it comes to as with everything.

Rob:

Exactly.

Rob:

Perfect.

Rob:

We've covered a lot and I want to be respectful of your time.

Rob:

As we sort of draw to an end, what, if we could summarize this in its entirety,

Rob:

what five tips would you give to somebody wanting to improve their gut health?

Rob:

And I know that's like saying how long is a piece of string, but if

Rob:

you were to just, uh, and it's like one of the, on one of those desiring

Rob:

questions, what would you take with you?

Rob:

But just broadly speaking.

Marillia:

Yeah.

Marillia:

So I'm going to say.

Marillia:

what I would do to improve gut health in, in the scenario of my clients.

Marillia:

Okay.

Marillia:

So in the, in that context, the generalized advice, we know eat a,

Marillia:

uh, plant rich diet, you know, colors, dietary fiber, probiotics, prebiotics, but

Marillia:

that doesn't really suit my, my people.

Marillia:

So I'm going to focus on that.

Marillia:

I would say number one, which is It may sound silly, but it's minimize the risk

Marillia:

of catching a stomach bug because that can, it can be life changing, you know,

Marillia:

and we don't really understand that because no one is really talking about it.

Marillia:

So that will be the one, the the first thing.

Marillia:

The second thing would be minimize the intake of unnecessary antibiotics.

Marillia:

Obviously they are important, they have a time and place, but as I

Marillia:

said, unnecessary because we know that they are essentially a bomb.

Marillia:

If you're dealing with symptoms, understand what's causing them.

Marillia:

I always think that symptoms are signs that something isn't right.

Marillia:

So don't ignore them and look for the, the, the, why, you know, ask why you

Marillia:

are experiencing symptoms, address the underlying cause of the problem.

Marillia:

And work with a specialist to overcome dietary restrictions, you know, because

Marillia:

at the end, that's what you really want.

Marillia:

You want to be able to eat a variety of foods,

Rob:

definitely something.

Rob:

I mean, yeah, those words are ones to live by for sure.

Rob:

Okay.

Rob:

Final question.

Rob:

Uh, taking everything into account that you've, that you've learned over the

Rob:

years, uh, how do you live your life?

Rob:

Uh, and there'll definitely be some overlap with the previous answer.

Rob:

I'm sure But how are you optimizing your day to day lifestyle, uh, sort

Rob:

of based on these sort of functional medicine philosophies that we discussed

Rob:

to sort of, yeah, live your best life?

Marillia:

So I truly think it's about nailing the basics, you know, and to be

Marillia:

very, very cliche health is well for me.

Marillia:

I lost my health and I know it's, you know, it doesn't matter what you have.

Marillia:

If you don't have your health, it's absolutely pointless.

Marillia:

So for me, it's really about nailing the foundations.

Marillia:

And as I said before, as well, it is multifactorial.

Marillia:

It's not, I will do this one thing that is going to be the solution,

Marillia:

but it's a combination of things.

Marillia:

Thanks.

Marillia:

It does require discipline because, you know, it's much easier to not think

Marillia:

about all the things that you need to do to achieve long term health.

Marillia:

Uh, but I prioritize sleep.

Marillia:

I make sure my meals are balanced, that I get enough color on my

Marillia:

plate, protein, dietary fiber.

Marillia:

I exercise daily.

Marillia:

I do strength training, cardio exercises, and then I also try to rest and have fun.

Rob:

Marilia, that is amazing advice, and I think Yes, there's

Rob:

definitely something that I need to sort of take on board as well.

Rob:

Where can people find you if they want to work with you?

Marillia:

Yeah, so they can find me, uh, online on my website,

Marillia:

which is gutfulnessnutrition.

Marillia:

com or Instagram and my handle is gutfulnessnutrition.

Rob:

Perfect.

Rob:

We'll be sure to link to all of those in the show notes as well.

Rob:

Marilia, thank you so much for your time.

Rob:

We really appreciate it and we'll have to do this again soon.

Marillia:

Absolutely.

Marillia:

Thank you, Rob.