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Hey there, Alex, it's great to finally

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connect and to have

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you on the podcast today.

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I know it's a little early there.

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And as you've just mentioned, you've just

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got your first born

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that's come into your life.

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So I really appreciate

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the time that you're taking.

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Now, familiar, I'm sure that most people

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in this space who are familiar with

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molecular hydrogen are to at least some

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extent familiar with you and your work,

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especially as you've been on the podcast

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circuit a lot in recent times.

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But for those in the audience who maybe

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just aren't familiar with you and your

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story, would you mind just running us

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through how you end up in this space?

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Yeah.

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So this would be going back about a

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decade, maybe a little bit more.

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I was in a completely different field.

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It gave me a lot of freedom

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financially and time wise.

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And so my time was

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spent largely exercising.

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You know, and competing a little bit of

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competing and CrossFit, but helping

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friends get prepped for

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fights in martial arts.

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I was training four to six hours a day

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and I got hit with the mystery virus.

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It caused an autoimmune like response.

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I developed sudden onset narcolepsy.

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I was sleeping 16 plus hours a day.

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If I sat down for more than

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a minute, I'd fall asleep.

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That was a narcolepsy aspect.

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And I had central nervous system fatigue.

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So my strength was normal, but I couldn't

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do anything explosive.

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Like couldn't jump an inch

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off the ground, basically.

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Sorry to interrupt.

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Was there anything sort of postural then

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sort of a sort of a POTS component?

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Do you think?

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A postural orthostatic hypertension sort

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of element to that, just with that sort

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of CNS fatigue or it just sort of screams

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that sort of

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autonomic dysregulation to me.

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Or do you think there was another

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underlying trigger there?

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Yeah, I mean for hypertension, my blood

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pressure by memory wasn't that abnormal,

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but that was something.

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Especially when this happened, my resting

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heart rate was in the mid thirties.

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My blood pressure was

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like a hundred over 70.

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I remember it spiked a little bit, but

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nothing that the doctor

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itself was concerning.

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What was the most concerning is my

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C-reactive proteins, which

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were 35 milligrams a liter.

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Wow.

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It's like...

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Or line cancerous.

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Yeah, it's a hundred times abnormal, you

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know, and now mine are undetectable.

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So, you know, 150, 200 plus times higher

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levels of inflammatory

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markers than what I currently have.

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So that lasted a few months and all of a

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sudden the dust cleared and things

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started settling back down to normal.

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And by normal, I mean my C-R-P dropped to

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like three, which is still what you'd

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expect when you're sick,

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when something is going on.

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But not 34.

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But when that happened, I had developed

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osteoarthritis in 11 joints.

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So the high levels of inflammation for

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months had basically ravaged every joint

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that I'd had a previous injury in.

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Doctors told me that I should never work

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out again, you know, put me on high

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levels of like anti-inflammatories and

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cortisone injections.

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And I just knew that

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wasn't a forever solution.

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At 29 years old and having my life

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largely been about fitness and exercise.

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So I just dove deep into what we now call

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biohacking and looking for absolutely

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anything that could regulate the

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inflammatory response.

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I came across research on hydrogen,

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hydrogen water and bought

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a machine for like $5,000.

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Went on my Mary Way.

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I was doing countless other things,

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various supplements, various, you know,

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therapies, doing cold exposure, you know,

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sauna, like doing all this, this stuff.

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And also was doing the

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anti-inflammatories in

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the cortisone injections.

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I must have loved you.

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Yeah, about nine months in, I fainted in

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the gym a few times.

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I wasn't processing my nutrients.

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I developed multiple ulcers.

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So I had to abruptly stop the

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anti-inflammatories.

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Then my inflammation spiked again.

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All my joints froze.

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I couldn't put on a shirt, you know,

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couldn't, had to lie down

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to put on socks type thing.

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And I had to go back to the drawing board

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because obviously none of the biohacks I

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was doing were properly working.

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Only the drugs were working

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and dove back into the research.

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And I found new studies on hydrogen water

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and molecular hydrogen.

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And they kind of pissed me off because I

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had this $5,000 machine and it was doing

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nothing for me, but it just dawned on me.

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Well, what dose am I getting and what

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dose are they using in the research?

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So I started buying the full papers to

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read the material and methods, quickly

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discovered that not a single one of the

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clinical trials was using an electrolysis

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machine like I'd bought.

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Um, they were all reporting

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concentrations and dosages of age two.

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I had no idea what I was getting.

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I found a reagent to test the hydrogen

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and it was undetectable.

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I had to triple the

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input to detect anything.

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So it was, you know, 0.03 parts per

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million is what I was getting, which is a

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small fraction of the minimum observed

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therapeutic threshold to have any

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physiological effect and the minimum

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threshold to do anything in the body is

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not what's going to work or work for the

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best, you know, for, for anything.

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So that, uh, gave me a bit of hope and

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there was nothing commercially available

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other than these,

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these electrolysis devices.

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And, uh, I started doing some tweaking

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and then I found there was some emerging

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stuff coming out and I started testing

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yet it had loads of problems.

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But, uh, basically between my own, like

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Jerry rigging of getting these reactions

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done and trying to maximize it, I started

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getting to about three parts per million

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and drinking several

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liters of the water a day.

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Um, I was pressurizing

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it in like thermoses.

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Um, a few actually exploded in my fridge

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from the pressure build up.

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Like, so that was a fun issue, but, uh,

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within like a week and a half of getting

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in this high dosage, daily dosage of

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hydrogen, my joints all loosened and I

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started feeling energy again and feeling

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better and I started thinking, wow,

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there's, there's something here.

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Um, but, uh, I had a bit of a sober

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second thought, um, cause I was using

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elemental magnesium, uh, doing this

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reaction and I knew enough about the

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basic chemistry to know that I'm making

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hydrogen, but I'm not a chemist and I

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didn't know if there were any side

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reactions that were making something

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toxic or harmful, uh, am

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I doing something wrong?

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Exactly.

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Are there heavy metals?

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Um, so I tested the magnesium I was

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getting and I pulled in this magnesium.

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I'd found sources in, in like Eastern

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Europe and in China, right?

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Because the, the stuff controlled in the

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U S like eventually, which is what I'm

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using, I'm using a pharmaceutical grade

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of the magnesium, but I had to go through

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an extensive background check to, to get

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it and export it, you know, through the

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state department, because it's heavily

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controlled right in the U S.

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Um, and the stuff I was getting in from

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Eastern Europe and China was never

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labeled as magnesium.

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It was always something like

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silver paint powder, right?

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Like, um, because I learned it was

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illegal for them to export.

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So, um, I tested it.

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The heavy metals were high, but not

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dangerously high, like high to be doing

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every day for the rest of my life.

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Yeah.

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Chronically.

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Exactly.

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Um, and, uh, uh, uh,

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found my founding partner, Dr.

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Holland, he, he's a

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PhD, uh, organic chemist.

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Uh, he's, he's

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originally from the UK actually.

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Um, and, uh, he's from the pharmaceutical

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industry and I asked him to take a look.

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At first he told me, I'm

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going to save you the money.

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This is the worst pseudoscience I've ever

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heard in my life and gave me a long list

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of reasons why this wouldn't have a

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physiological effect.

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And even if it did, why you'd want to

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inhale rather than drink.

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Um, fortunately I had read every single

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paper at that time on molecular hydrogen

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and its physiological

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effects, um, including.

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Data head to head from drinking water to

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inhalation and the difference in bio

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availability and

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different organs and tissues.

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So I shared this with him.

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I rebutted every one of his points and he

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said, well, you know, I'm shocked.

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I still don't really believe it, but

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peers, there's enough for

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me to take a look for you.

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Sure.

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I'll, I'll take a look.

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This is my right.

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And, uh, he went on looking at my

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formulation and the chemistry and every

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day I just sent him a new study.

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Um, just to pique his interest.

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I was really excited at this time because

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it had had such a profound effect on my

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own health and I want to keep doing it.

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Uh, and serendipitous serendipitously, I

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sent him a one paper on a certain heart

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disease model that I was not aware of,

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but he was a lead chemist developing

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small molecules to target

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that disease at the time.

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And it was, uh,

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a phase two ish style, like, uh, double

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blind clinical trial.

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And, uh, he called and asked if I wanted

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to meet for lunch and that

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he had some findings for me.

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And, uh, you know, he'd made some tweaks

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to, to my formulation, but importantly,

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he wanted to talk about that paper.

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And he said the other papers he were, he

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was just having to trust the conclusions

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because he wasn't really a subject matter

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expert, but, uh, he remarked that he was

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on this model and told me he was

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developing small molecules for it.

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And he wishes the molecules, his company

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was developing worked as well as this

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paper, and he basically said, are you

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sure you just want this as a do it

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yourself project,

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like nobody's doing this.

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Shouldn't like you're sure you don't want

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to commercialize this.

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And, uh,

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I thought long and hard about it.

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Um, you know, I, I thought

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who am I to enter this field?

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I have no background

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in this field, right?

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Um, I, uh, don't want to go into

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something that requires expertise and

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just be pushing something

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that I don't understand.

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Um,

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but I'd also promised myself because I

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abandoned some business ideas that years

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later, other people thought of and, and

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you know, what went and distributed.

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So I promised myself that I'd never let

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an opportunity like that slip again.

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Um, so I started doing my due diligence.

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I spoke to attorneys, uh, the first

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attorney I spoke to, um,

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cause I was thinking about raising, you

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know, funds and if I was going to need

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to, and I didn't want to, but if I was

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going to need to, what it would go and

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strap this.

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Yeah.

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Yeah.

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And, uh, he basically like I told him

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what I was doing and the research.

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And, uh, um, by this time we'd actually

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developed a tablet that was working.

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And after an hour meeting, he said,

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listen, I'm not going to charge you for

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this meeting and I'm not going to charge

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you to get all this set up.

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So long as you shake my hand and say that

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I'm going to be your

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corporate attorney as you get going.

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So that gave me even more faith that,

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okay, like maybe like there's something

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here, there's something here, right.

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And I'm getting this

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kind of encouragement.

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And then I, I, uh, hand pressed bottles

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for about, you know, 40, 50 friends,

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family members, friends of friends that

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we're dealing with various chronic like

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pain issues, like,

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especially like exercise related.

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And the response was just overwhelming.

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Everyone's like, what did you give me?

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This is, this is like magic.

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Like this is fixing this or fixing that.

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And all of these, uh, confirmations along

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the way kept me going.

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Um, the first year, year

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and a half was arduous.

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Um, it only took a few weeks for us to

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finalize the formulation and a mortar and

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pestle and making 20 at a time, but

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making millions at high speed is a

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different beast entirely.

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And it was 15 failed scale of attempts

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over a year and 3000 iterative

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adjustments to formulation and process

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before we got our first working

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formulation that didn't work nearly as

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well as those firsthand pressed tablets.

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You know, and, and to be frank, um, even

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the tablet we have today doesn't work

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quite as well as the first hand pressed

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tablets because everything you do in

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manufacturing can take away, but we're

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pretty darn close to, to what we did day

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one, but now we're at least 10,000 get of

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adjustments into formulation process to

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continue refining, continue perfecting

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and be able to make it high speed, but

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now I had a working product and I can

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make it, but the next question was, do I

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want to just be like a zealot believer

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or, or do I want to put my money where my

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mouth is and see if this does work

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because I can't look

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at myself in the mirror.

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I can't sleep if I think that I'm just

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being a fraud, right.

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And don't know.

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So I set out on the next task.

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I emailed every first and corresponding

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author on every single human study on

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hydrogen at the time and quite a number

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of the rodent studies offering free

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product, free placebo and donations.

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If they wanted to use my tablet in the

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research, I got some bites that kept

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going and, uh, I'm a

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big believer in truth.

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So how most companies conduct research is

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when they're paying for research is under

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a research agreements, um, and results

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can only be published

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if the funding body.

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Like agree with the findings.

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Right.

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I just don't believe that's ethical.

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We don't know the truth if we don't know

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what doesn't get published because if it

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takes a company 10 times to find the

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result they want, then it doesn't work.

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Didn't work nine times.

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Right.

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Um, so cherry picking

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dates are just based.

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Yeah, exactly.

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And this has allowed us, like we have

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over 20 clinical trials.

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Now we have more clinical trials underway

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than we have published, but because at

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every step of the way, um, I'm allowing

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researchers to publish no matter what the

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outcomes are, right?

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They can publish if it doesn't work, they

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can publish if it shows harm.

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This allows them to get grants, you know,

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from governmental bodies and agencies and

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their, their

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institutions to pay their salaries.

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So the research we've done would have

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probably cost in the nine figures, but

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it's cost us maybe a

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million or $2 million.

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I haven't done the math, right?

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But we've done the research for one, 100,

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the cost of what most private companies

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do because we are taking this risk and we

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want truth to prevail.

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And if we find out, if we found out it

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didn't work or it's harming people, then

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I wouldn't have been able to continue on

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in the business anyways.

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Right.

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So I didn't want to be beholden to this

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whole like shareholder primacy, which is

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the biggest evil that's befall in the

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Western world that I have to do

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everything to protect earnings, you know,

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either this is showing that it's working

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and helping people or it's not right.

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Because I can always find something else

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to be my purpose and make money, but I'm

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not going to do anything for

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the purpose of making money.

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Right.

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Money is a tool for your purpose.

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It's not the purpose.

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Right.

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So that's why I

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structured things the way I do.

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And at this time now we have 21 structure

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function claims legal to like FTC, FDA

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standards in the U S uh, like I

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mentioned, we have over 20 clinical

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trials, a bunch of preclinical trials.

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We have more clinical trials on the

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hydrogen tablets than every other

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commercial hydrogen

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water product combined.

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And we have more

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underway than we have published.

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So our lead is just growing because of

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our philosophy for truth and for science.

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And, uh, again, really it's, it was a put

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in your money where your mouth is like

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I'm a believer, but I'm

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ready to be proven wrong.

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Right.

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And let's see what the data shows.

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Well, thank you for that.

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That was the most comprehensive

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introduction I've ever had from anyone.

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So that was amazing.

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And it definitely just speaks testament

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not only to your character, but the

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amount of effort you put into this and

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just trying to overcome your own issues.

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Um, I'd love to come back to the tablets

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a little later on the conversation.

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That's okay.

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So I've got a few more questions there,

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uh, but just kind of a quick tangent.

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I mean, I can't do a podcast without

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talking, uh, going on tangent quickly.

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Uh, did you ever find out what was really

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triggering, uh, your, your RA or the

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other subsequent issues, what is sort of

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mold issue or anything like that?

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Or they, they, they think

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it was a viral infection.

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Right.

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Um, it might've hit me

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a little bit different.

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Uh, so my roommate at the time who was

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also a high level computing athlete, um,

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it hit him different.

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He, uh, had to go to

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the hospital a few times.

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He had pneumonia.

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He missed a few weeks of work.

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Um, he didn't have the

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long lasting effects I did.

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I think what might've contributed to what

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happened to me is about a month prior.

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Um, I stupidly competed in the CrossFit

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competition about two days

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after I'd had food poisoning.

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And that left me so wrecked that I had

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like borderline Rabdo.

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Like I couldn't walk up the stairs.

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Like I slept on the couch because like in

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my house, I was on the second floor and

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like, I couldn't make it up the stairs.

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So like for a couple of days, I slept on

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the couch downstairs as my legs were like

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shaking and, you know, not recovering.

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Um, yeah, yeah.

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Again, I should have dropped out of that

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competition, but I was 29 and stupid and

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thought I was invincible.

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So I imagine that gut disruption and

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severe stress following of trying to

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compete after food poisoning is what

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triggered the response

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to the virus that I got.

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Yeah.

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And I, I, I, I'm not going to judge you.

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I grew up a competitive

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cyclist and, uh, it's different.

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It's a lovely sport.

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It's very safe until you fall off in

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which case it's not.

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But yeah, and I sort of

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trained myself into living.

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I gave myself, uh, a benign bradycardia,

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uh, used, yeah, same vibe.

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Used to sort of train until you threw up

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in your nose, bled, and then sort of

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wiped it down and just carried on.

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And this is, and then all of a sudden you

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hit that critical threshold and your 20s,

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where everything just

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starts to fall apart.

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There's a quote from a jujitsu competitor

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that I like quite a bit.

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Um, when you hit 30,

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you no longer get injured.

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You start collecting

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permanent disabilities.

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Like that.

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Um, yeah.

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And I think, yeah, there's definitely a

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law of diminishing returns, as you know,

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when it comes to, uh, to exercise.

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And I suppose it's, it's, it's quite a

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nice sort of way to sort of segue into

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the rest of the conversation.

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It's a bit of an automatic stress is a

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good thing, but too much is detrimental.

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Yeah.

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I mean, this is a book I'm writing that I

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hope to release by about July called the

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Stress Hacked and it's not

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just the body, it's the mind.

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So it's two books.

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Um, they meet in the center.

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You know, inverted kind of like yin yang,

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because we can't be strong in body

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without strength of mind and we can't be

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strong in the mind without health and

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strength and figure in the body.

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Um, but all of that, uh, I mean, hydrogen

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is a hormetic stress.

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It's just a very mild one.

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Right.

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And with every hormetic stress, whether

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it's emotional, psychological, whether

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it's physical, uh, you need a certain

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threshold for it to be therapeutic.

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But if you go too

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much, it can be harmful.

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And typically when you do too much, it's

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more harmful than the absence of it.

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And, uh, the right dose for any type of

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stress, whether it's physical or mental

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depends not just on the individual, but

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intra individual every day.

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What other stress do you have?

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What is your current state?

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Right.

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So that CrossFit competition that, that

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ruined me was no harder than any other

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one I'd done or my usual training.

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But because I just had food poisoning a

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couple of days before it was too hard.

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The entirety of that sort

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of LST at load as it were.

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Exactly.

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Right.

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And this is what a lot of

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people don't understand.

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And what I see is the big problem that a

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lot of people, even medical doctors are

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recommending universal protocols.

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Right.

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That this is your longevity stack of like

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core meat expressors and everyone should

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do this exact thing every day.

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And it's insane.

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And it really speaks to poor

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comprehension of how hormesis works and

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how our physiology works.

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Yeah.

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No, I couldn't agree more on this.

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I think it's definitely something we can

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come back to a bit later on.

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Um, yeah, my apologies.

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Uh, I'm the king of tangents.

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I am ADHD on top of everything else, but,

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uh, I'd like to maybe take a step back

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quickly if that's okay, Alex.

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And then, and talk more about, um, how

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molecular hydrogen is working now, uh, in

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our sort of initial discussion, I want

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you to go down the, the sort of the

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mechanism of hydrogen ions and how they

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sort of drive the production of ATP

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through the electron

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transfer chain, all of that.

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And you thankfully put me on the right

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track and, and sort of, uh, uh, yeah.

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Sort of pointed the conversation more

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towards sort of the semitic side of

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things, which is what we'll discuss now.

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Um, but as sort of a molecular level, I

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mean, you've, you've already sort of, uh,

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alluded to it with this discussion about

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hormesis, but how is molecular hydrogen

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fundamentally working to improve the

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function of the cell of the mitochondria

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and subsequently improve

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the health of the individual?

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It's closest to, to hormesis, but it's

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not really hormesis because we haven't

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found the upper limit

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where it's, uh, harmful.

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It's sort of like an anticipatory stress

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with which our body expects to be a

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stress, but is so mild that it never

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seems to appear toxic.

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Um, now we clearly

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evolved to anticipate this.

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Um,

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if you look at our last

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universal common ancestor,

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it actually fed on hydrogen

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as its fuel source, right?

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That spawned all life on the planet.

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Um, our mitochondria came from

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eukaryotes, which was sort of like a

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handshake deal between, you know, a

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hydrogen producing and a hydrogen

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consuming, you know, organism and, uh,

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uh, went out to that, that carried on

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through us now in living things,

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including the, uh, the, the, the, the,

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the, the, the, humans, we all have

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bacteria that produces hydrogen gas and

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much more relevant to human evolution.

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Um, we make our H2

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endogenously by fermenting fiber.

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Now, if you look at, uh, the diet or

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ancestral diets in our hunter-gatherer

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stages before the last 10,000 years of

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modern horticulture, we were consuming

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100 to 150 grams of

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dietary fiber per day.

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Right?

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Tremendous amounts.

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Today, the average person in the Western

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world gets 10 to 15 grams, but that

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includes raw food vegans,

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who are getting like 60 to 80.

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The average person on a standard American

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diet, eating a fast food and takeout food

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diet, is getting zero to

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three grams of fiber a day.

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Want to talk about the carnivores?

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Yeah.

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Yeah.

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Bacteria is like any other living thing.

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If you stop feeding it, it dies.

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We now know that even supplementing with

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fiber, for a lot of these people, once

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you hit middle age, you've had a poor

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diet, you haven't eaten fiber your life,

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the hydrogen producing bacteria have died

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off and what has taken over are

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methanogens, which are producing methane

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right instead and

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actually consuming hydrogen.

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So you end up with this hydrogen

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deficiency and hydrogen seems to be this

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ancient signal that we have.

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So yes, there's a very, very mild direct

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stress to the

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mitochondria that attenuates NFKB.

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So that's how it's regulating our

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inflammatory responses.

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It's activating the NRF2 pathway.

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That's how it's regulating the redox

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status, the harmony between our

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endogenous antioxidants and our

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beneficial stressors, right?

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Like nitric oxide and

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H2O2 and H2S and so forth.

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So hydrogen is kind of this supervisor.

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It's a signal that comes and the dials

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start getting turned.

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So hydrogen doesn't activate or inhibit

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anything universally.

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You look at all of these markers that we

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see in the literature and there's

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examples of hydrogen activating them or

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attenuating inhibiting them, right?

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Depending on the context, but always for

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a beneficial response.

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So for instance, in the longevity space,

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a lot of people talk about autophagy.

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When you think that you always want to

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activate autophagy, which is simply not

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true, there's a lot of instances where

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you do not want autophagy activated.

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So hydrogen in many instances activates

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autophagy, but in key instances in the

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research, it has completely inhibited

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autophagy, such as after drowning

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resuscitation, after

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heart failure, right?

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These are instances you don't want

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autophagy happening and

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hydrogen's inhibited them.

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It's the same thing with

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oxidative stress and inflammation.

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Now,

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these are important parts of our

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physiological function.

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What's dangerous about them is when

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they're chronically dysregulated, either

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too much or too little.

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More often than not, it's too much, but

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there are plenty of

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instances where it's too little.

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So for instance, a lot of antioxidants,

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like they, one don't work.

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The research has shown that high dose

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antioxidant therapy leads to higher

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all-cause mortality.

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Reductive stress.

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Yeah, reductive stress, exactly.

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So antioxidants can be good for some

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people, some of the time, because if

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you're in chronic oxidative stress and

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you have some more antioxidants, it can

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bring you back down.

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But if you're just loading up the dose

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and taking more and more and more, and

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you're doing that every day, you reach a

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point where you went to reductive stress,

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which is just as

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harmful as oxidative stress.

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Hydrogen actually is not doing this.

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It's regulating our

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endogenous productions.

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It's not working as a direct antioxidant.

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So there's some cool research in say rats

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to enforce swim tests.

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And this is a model that we use to

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evaluate stress, you

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know, exercise induced stress.

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In the hydrogen plus force swim test

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group, the rats actually see a higher

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spike in oxidative

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stress and inflammation.

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So their stress response gets

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potentiated, but then they rebound to

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homeostatic function faster.

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So it's as if they worked out

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harder and recovered quicker.

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So hydrogen is not blunting the the

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hermitic stress response, the adaptive

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stress response of

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stressors like exercise.

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It's in fact potentiating

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them, but then protecting

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against dysregulation and bringing you

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back to harmony faster.

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So all the jumbos can relax about them

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taking it's not like taking high dose of

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urgency off your workout and then just,

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yeah, it's not gonna

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bludger hypertrophy gains at all, right?

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It's actually gonna potentiate them.

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So that's really interesting.

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And this is what we're seeing.

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And hydrogen is doing

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this for a lot of markers.

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I know in our talks you

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mentioned PGC1 alpha, right?

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And a lot of these markers that are

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linked to things like caloric restriction

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and fasting, hydrogen seems to mimic them

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sometimes, you know,

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in the right context.

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Now, what I find very interesting, and I

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still don't have a full grasp on what

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this means from an evolutionary

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standpoint, but throughout our

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hunter-gatherer phase, our times of

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caloric restriction were typically the

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inability to hunt and

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secure meat and fat.

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So we would have relied on more

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plant-based food sources, which back then

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had far more fiber and

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were less calorically dense.

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So we would have been getting enough

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nutrients and enough fiber, but we

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wouldn't have been getting enough

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calories and enough protein, right?

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Going into this deep like fasting-like

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state, this caloric restriction that

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activates all these pathways.

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Well,

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interestingly, during these

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times of famine and fasting,

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their hydrogen, endogenously, would have

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been amplified, like our ancestors,

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because they would have been eating more

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and more plant-based

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foods full of more fiber.

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So they would have been getting these

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huge erratic spikes of hydrogen, which

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perhaps protected them

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in these times of famine.

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And perhaps this is a signal that we've

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brought with us to modern times.

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So what's the

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protein-sparing effect, do you think?

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Well, we do know there's one interesting

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study in Drosophilia, where they

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stop food source on these fruit flies to

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see how long they survive.

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And the group that's been

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supplemented with molecular hydrogen,

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they survive for substantially longer.

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Then, you know, the

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fruit flies have the control.

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So there's some

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interesting factors there.

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Again, not only is it activating these

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caloric restriction-type pathways, but

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it's preventing death

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and harm from extended.

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So it's regulating our response to these

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physiological stressors.

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Yeah, that's fascinating.

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Okay, well, you've

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definitely answered all my questions.

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And I'm glad to see that you sort of at

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least agree on the fact that, well,

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sorry, post-cholesterol words, that you

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like my idea that it's going to also

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support mitochondrial biogenesis by way

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of potentially upregulating PGC1 alpha,

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which for the audience is a, I think, is

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technically speaking transcription

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factor, that then drives the production

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of more of these

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mitochondria within the body,

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which for most people, and which is

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something I think a lot of people seem to

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forget about is they don't realize that

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there is this high level of mitochondrial

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turnover that's constantly happening.

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And as you alluded to earlier, like

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everything else,

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mitochondria become damaged.

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And when you're in a highly inflamed

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state, you're going to not only lose the

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capacity of those mitochondria, but

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you're also going to

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lose mitochondria in tandem.

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I mean, I'm sure you're familiar with Dr.

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Robert Navier's work on

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the cell danger response.

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I'd be actually quite

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interested to see what he thinks.

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Are you familiar with

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the cell danger response?

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No, no, not off the top of my head.

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Okay, so Dr.

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Navier, it's more of a thing in the sort

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of the CFSME community.

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Obviously, people are struggling with,

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yeah, your chronic

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fatigue syndromes, but Dr.

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Navier posits essentially that when the

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cell is stressed, the mitochondria

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particularly is going to go into what's

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called a cell danger response state.

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And it's going to inhibit it, which is

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going to inhibit the ability to utilize

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fatty acids to drive ATP to production

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through oxidative phosphorylation, and

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that they're then going to

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sort of rely more on glycolysis.

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And in doing so, you are going to down

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regulate the metabolism of that cell to

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the extent that it actually is not able

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to, yeah, that you then start to lose the

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ability of that cell to effectively

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communicate with neighboring cells, but

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also just to produce ATP

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in the effective range.

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And you cycle through what is essentially

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cell danger, CDR1, 2, and 3.

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And individuals who are in this CDR state

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tend to sort of get stuck in CDR1 and 2,

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which are these

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states of cellular arrest.

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And I'm just sort of trying to plug it

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all together here, but I would be kind of

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interested to see what

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molecular hydrogen would do

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just with regards to his work.

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I'd be happy to send you

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this information on his work.

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Yeah, send it all, I'll

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take a deeper look for sure.

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Yeah, no, I think it's definitely one of

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the metabolic theories that explains a

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lot of cellular dysfunction and not only

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chronic fatigue, but why people get stuck

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in a state of chronic inflammation and in

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a state of chronic hyper

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immune reactivity as well.

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Alex, I'd love to have a deeper dive into

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hydrogen and the gut.

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Now, I know you've talked about this

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previously, and maybe I'm butchering

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this, so please feel free

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to correct me if I'm wrong.

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But from what I understand, hydrogen is

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involved in the production of short-chain

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fatty acids, is that correct?

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So we don't know the exact mechanisms

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yet, but we have shown in research that

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it can increase certain short-chain fatty

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acids like propionic

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acid, butyrate acetate.

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There's been quite a number of studies

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showing improvements to the microbiome.

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We have again shown with the tablets that

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we can reduce calprotectin, so there is a

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lot of gut protective

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effects that are happening.

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We can activate hormones in the gut, like

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we've regulated ghrelin and GLP1 in

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clinical trials and pre-clinical trials.

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So there's a lot of gut-based responses

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that are happening that mechanistically

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we do need to uncover more, but it could

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in part be due to this constant ebb and

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flow of gases that we have in our gut

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right now, and how modern lifestyle has

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dramatically shifted this dynamic away

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from what we evolved to expect.

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So by supplementing with high-dose

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hydrogen, especially for the gut water

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because it's getting into your gut, this

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could be basically substituting for what

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we're lacking in our lifestyle.

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Okay, and just on that train of thought,

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if you've got more of these short-chain

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fatty acids, one would assume that you're

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going to sort of develop more acrimensia

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and other beneficial bacteria.

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They're not only going to increase.

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There is some research that hydrogen can

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increase acrimensia too.

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Okay, or directly.

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Yeah, well, that supplementing with

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hydrogen water leads to

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higher levels of acrimensia.

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Now, whether that's

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direct or not, we don't know.

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Most of the things hydrogen is doing is

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indirect because when it's tipping the

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scales on our system and it's dialing up,

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dialing down in all these various ways,

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there are countless

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downstream changes that occur.

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So with everything hydrogen, it seems to

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be largely systemic, at least to the

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tissues that are

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being properly saturated.

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So it's still unraveling the rat's nest

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of what's downstream of what

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in terms of hydrogen's action.

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Yeah, and then just on the GLP1 side of

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things, have you done any investigations

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or research as your team into the

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metabolic effects of hydrogen, maybe say

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relative something like GLP1 agonist?

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Is there any data out there to show that

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these compounds are effective at helping

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to regulate those satiety hormones?

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So we have, I think it's now seven

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clinical trials showing substantial

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improvements in body composition and

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metabolic health, including ones that are

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under peer review right now.

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We've regulated, like I mentioned, GLP1.

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We returned the peaks and valleys to

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ghrelin showing proper hunger responses.

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We've modulated the neurochemistry

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involved in satiety.

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We consistently show improvements in

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various metabolic markers as well, such

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as blood sugar insulin, cholesterol,

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triglycerides, everything like that.

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Again, it's going to be a lot more subtle

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than throttling a GLP1 agonist full time,

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but hydrogen isn't a sledgehammer, right?

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What it is, is it's a fine tool to

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recalibrate and then over time, your body

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slowly gets more and more efficient and

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does things more and more properly in how

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we evolve to behave.

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But it's not going to be

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shocking changes overnight.

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We're seeing the best metabolic effects

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after three months, six months.

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The longer you take hydrogen, the better

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the results are getting.

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Yeah, no, I mean, that makes perfect

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sense, of course, because I think people

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take this sort of very reductionist view of appetite at the moment

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anywhere that it's just GLP1.

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But when you're in an inflamed state, and

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as most people struggling with metabolic

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disease are, you're going to have high

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levels of inflammation, you're going to

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have low levels of dopamine, you're going

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to have dysregulated ghrelin,

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dysregulated leptin signaling, all of

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which are going to

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feed into this cascade.

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It's not just about the GLP1.

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And subsequently, yeah, if you can work

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to improve that environment, to sort of

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re-model or regain that homeostasis, I

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would have met with something like

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molecular hydrogen, I would assume that

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you are then rebalancing the entire

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satiety system within the body.

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And I suppose it's just taking a sort of

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a root scores approach to it apart from a

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post as you sort of mentioned, just

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that's rocking GLP1 and hoping to god you

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don't end up with

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pancreatitis in 10 years time.

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Yeah, and that's the thing.

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Hydrogen is, it's not

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acting like how we define a drug.

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It's not having a direct effect on a

Speaker:

certain receptor,

Speaker:

right, or enzyme in the body.

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Like hydrogen is playing this regulatory

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role, like a supervisor within our cell

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that's directing subtle changes, and then

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our body starts to correct its own path.

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Yeah, definitely.

Speaker:

What do you think about the idea of sort

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of running a GLP1 alongside

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something like molecular hydrogen?

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I know it's a bit of a blunt, a sort of

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low hanging question, and definitely

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something that you'd want to

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sort of just clip on a reel.

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But I think that's something that people

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would want to be interested in.

Speaker:

Is that, I mean, just speaking from your

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own position, would that be something

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that you would sort of well endorse, but

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at least

Speaker:

hypothetically say is a good idea?

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So actually, this gets into what I think

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is the future of the research.

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And we've now published a number, I think

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half a dozen of preclinical trials.

Speaker:

And we have many more that are either

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under peer review, under manuscript prep,

Speaker:

or in planning, where we're utilizing

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concurrent use of the hydrogen tablet

Speaker:

delivering an approved pharmaceutical

Speaker:

ingredient, right, an active

Speaker:

pharmaceutical ingredient.

Speaker:

What we're finding over and over again is

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that hydrogen is acting synergistically

Speaker:

to potentiate the responses of these

Speaker:

drugs, while also

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mitigating the side effects, right?

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So it could lead to futures where a lot

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of these drugs, we can be delivering them

Speaker:

in much smaller dosages, also reducing

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the side effects, getting better results

Speaker:

and improving people's health, because

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there are many, many instances where we

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do need direct pharmaceutical

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intervention, you know,

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for a lot of specific states.

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So actually, there's certain, you know,

Speaker:

GLP1 agonist molecules that are available

Speaker:

in say powder form that we've identified

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on our shortlist to be doing research to

Speaker:

look at the combination usage of them

Speaker:

with the hydrogen

Speaker:

tablet as a delivery method.

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And this is a future channel I am going

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into that we're actively going down.

Speaker:

It is exploring the use of the hydrogen

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tablet as what's called a, you know, a

Speaker:

pharmaceutical

Speaker:

excipient that enhances the

Speaker:

availability of the compound

Speaker:

or reduce side effects, like basically a

Speaker:

functional excipient.

Speaker:

So I don't want to

Speaker:

register hydrogen as a drug.

Speaker:

I don't think it fits

Speaker:

into the drug dynamic.

Speaker:

I don't think it works as a standalone

Speaker:

drug on any one disease, but

Speaker:

basically getting it through the

Speaker:

regulations like this, a whole wide array

Speaker:

of pharmaceuticals could be added to the

Speaker:

tablet delivery method, work

Speaker:

complementary or synergistically, reduce

Speaker:

side effects, and basically

Speaker:

be great for everyone involved.

Speaker:

From pharmaceutical companies who who are

Speaker:

putting in less of their expensive

Speaker:

ingredient to get the same effect and

Speaker:

probably charging the same on the market.

Speaker:

So making more profit in that sense, but

Speaker:

for consumers getting better health

Speaker:

results with lower side effects, you

Speaker:

know, and better

Speaker:

long-term improved health.

Speaker:

So it's something I'm

Speaker:

really excited about.

Speaker:

And that's what we're going to be going

Speaker:

down more the next few

Speaker:

years, five years, 10 years.

Speaker:

I mean, that's incredible.

Speaker:

I mean, I was aware of the fact you were

Speaker:

compounding America hydrogen with various

Speaker:

nutraceutical agents, things like PQQ, I

Speaker:

think chromium as well.

Speaker:

There are a few tablets in the market

Speaker:

that you've got that include those

Speaker:

specific molecules, but I didn't have any

Speaker:

inclination or understanding that you're

Speaker:

going down the the

Speaker:

pharmaceutical rabbit hole.

Speaker:

So that's incredibly interesting.

Speaker:

And yeah, I look forward to

Speaker:

seeing the results of that.

Speaker:

Unfortunately, I'm a synthetic chemist.

Speaker:

I'm a biochemist, so I

Speaker:

can't offer you insight there.

Speaker:

But yeah, that sounds fascinating,

Speaker:

something I'll definitely keep my finger

Speaker:

on the pulse, the pulse on.

Speaker:

Now,

Speaker:

Alex, I've heard you sort of talk about

Speaker:

and discuss various other ways in which

Speaker:

hydrogen can be introduced to the body.

Speaker:

Speaking of other

Speaker:

ideas you have, I suppose.

Speaker:

So looking at it from a topical

Speaker:

standpoint, I know it's inhaled.

Speaker:

Do you think that there's a sort of a

Speaker:

solid future there as well?

Speaker:

I mean, I foresee molecular hydrogen

Speaker:

being utilized from a topical standpoint

Speaker:

to maybe deal with autoimmune conditions

Speaker:

like exomens, rices, where there's a high

Speaker:

inflammatory load locally on the skin.

Speaker:

And obviously, I assume too, just

Speaker:

speculating here that there would be some

Speaker:

sort of anti-aging effects from a

Speaker:

different sort of...

Speaker:

Yeah, wrinkle reduction.

Speaker:

There's actually research showing reduced

Speaker:

wrinkles with bathing in hydrogen water

Speaker:

and algae leaves on fruits.

Speaker:

So I think the future, we're going to

Speaker:

drink it, we're going to bathe in it, and

Speaker:

we're going to inhale it.

Speaker:

And when you look at all three of these

Speaker:

routes of administration, they all have

Speaker:

different pharmacokinetics.

Speaker:

They saturate different

Speaker:

tissues to different extents.

Speaker:

So there is some crossover, but we're

Speaker:

going to be able to identify better and

Speaker:

better as time goes on.

Speaker:

For this model,

Speaker:

we want to say bathe and

Speaker:

inhale or bathe and drink.

Speaker:

And we're going to be able to develop

Speaker:

better suggested protocols.

Speaker:

Now, I do want to say

Speaker:

again with all hermudic agents,

Speaker:

developing these standards in

Speaker:

double-blind RCTs are important from a

Speaker:

population standpoint, but every person

Speaker:

is going to have different results and

Speaker:

you're going to want to adjust it based

Speaker:

on your current state.

Speaker:

But we will be able to identify at least

Speaker:

that inhalation is better for this,

Speaker:

drinking is better for that.

Speaker:

For instance, what I'll say, bathing,

Speaker:

obviously it's getting to a higher

Speaker:

concentration, far higher in your skin,

Speaker:

in your muscle and

Speaker:

connective tissues and such.

Speaker:

Inhaling, it's obviously

Speaker:

getting higher to your lungs.

Speaker:

It's getting substantially higher to your

Speaker:

muscles and skeletal tissue than

Speaker:

drinking, but not bathing.

Speaker:

It's getting higher to your brain than

Speaker:

drinking, but drinking the water is also

Speaker:

activating gut derived hormones like

Speaker:

ghrelin, which have

Speaker:

an effect on the brain.

Speaker:

So I think for brain issues,

Speaker:

you want to inhale and drink.

Speaker:

Drinking is obviously

Speaker:

getting to your gut the best.

Speaker:

It's interacting with

Speaker:

the microbiome the best.

Speaker:

It's getting to your liver

Speaker:

at the highest concentration.

Speaker:

So all of the metabolic outcomes of

Speaker:

hydrogen are our best through drinking

Speaker:

high concentration water, but we're going

Speaker:

to be finding out more

Speaker:

and more as time goes on.

Speaker:

And this is a real area of research focus

Speaker:

to figure out which method at what dose

Speaker:

is optimal for what condition.

Speaker:

And I've dove into the inhalation space

Speaker:

where we're just gearing up to announce

Speaker:

the soft launch of Inhale H2.

Speaker:

That's a project that myself and Dr.

Speaker:

Tyler LeBaron have

Speaker:

worked on for seven years.

Speaker:

He's joined us as our

Speaker:

chief scientific officer.

Speaker:

So this is the first product he has ever

Speaker:

endorsed because he's the co-inventor and

Speaker:

it is truly new and novel.

Speaker:

We are the first inhalation device on the

Speaker:

market that matches what

Speaker:

can be done in the research.

Speaker:

You can basically choose

Speaker:

anywhere from 1% up to 4%

Speaker:

with every decimal point in between of

Speaker:

hydrogen and your time.

Speaker:

But the key is

Speaker:

it's a full

Speaker:

re-breathing mask with a bladder.

Speaker:

We've developed the system

Speaker:

to mimic human breathing.

Speaker:

So every breath you take is that

Speaker:

controlled exact percentage of hydrogen.

Speaker:

Whereas with these cannulas,

Speaker:

you might breathe in a liter, two liters

Speaker:

at once in a deep breath,

Speaker:

but that's in one second.

Speaker:

And now you didn't get

Speaker:

100% of that hydrogen in.

Speaker:

That breath is maybe 0.1% or 1% depending

Speaker:

on the flow rate of H2 because these

Speaker:

nasal cannulas are constant flow rate and

Speaker:

they're trickling in.

Speaker:

And they're a fraction of what your

Speaker:

actual resting rate of inhalation based

Speaker:

on minute ventilation

Speaker:

and tidal volume are.

Speaker:

And most of the H2 is just wrapping up

Speaker:

straight out of your mouth.

Speaker:

Yeah, it's sort of a Hindenburg wake that

Speaker:

happened right there.

Speaker:

Yeah, so we developed this machine to

Speaker:

mimic human breathing and to work like

Speaker:

they're not using any of these machines

Speaker:

from China or Japan

Speaker:

in the clinical trials.

Speaker:

They're mixing gas tanks and sending them

Speaker:

to 60 or 100 liter a minute flow rates so

Speaker:

that every breath you take

Speaker:

is guaranteed to be that dose.

Speaker:

We figured how to do this with these

Speaker:

one-way valves and this inflatable

Speaker:

bladder, where even at a 12 liter a

Speaker:

minute flow rate, you can guarantee that

Speaker:

every breath you take

Speaker:

is the exact percentage.

Speaker:

Yeah, I believe again, correct me if I'm

Speaker:

wrong, but I think the issue with the

Speaker:

Japanese units is that they just

Speaker:

under-dosed the amount of hydrogen.

Speaker:

They got so wrong.

Speaker:

Yeah, they got so wrong.

Speaker:

Yeah, so you ended up underdosing it.

Speaker:

Yeah, so basically, we breathe at rest,

Speaker:

like say sleeping 68 liters a minute.

Speaker:

As we're sitting talking at a computer

Speaker:

like this, we might breathe 10 liters a

Speaker:

minute, 12 liters a minute even.

Speaker:

Most of these machines at the 4% gas are

Speaker:

at a constant flow rate of

Speaker:

one or two liters a minute.

Speaker:

Now, at a constant flow rate, so it's

Speaker:

just coming in at a constant rate, you'd

Speaker:

actually need 60 to 100 liters a minute

Speaker:

to make sure that every

Speaker:

breath you're taking is at 4%.

Speaker:

So that's what we've resolved.

Speaker:

All you can breathe is from the bag.

Speaker:

Everything you get is from our reservoir,

Speaker:

which is a bladder that

Speaker:

fills up and then contracts.

Speaker:

So you can open the door and see the bag

Speaker:

filling up, contracting with your breath

Speaker:

and know that everything

Speaker:

you're getting is just 4%.

Speaker:

That's incredible.

Speaker:

What's the ET on that project again?

Speaker:

So our betas got great feedback.

Speaker:

We've made all the changes.

Speaker:

We're actually just finalizing more of

Speaker:

the processing details.

Speaker:

We're putting out a soft launch offer.

Speaker:

So we have such overwhelming support

Speaker:

between myself and Dr.

Speaker:

LeBaron's connections.

Speaker:

Everyone wants this machine.

Speaker:

The last thing we want to do is order

Speaker:

30,000 of them and find that there's a

Speaker:

problem, like a small problem on the one

Speaker:

that derails our launch.

Speaker:

So we're doing a lot of things.

Speaker:

We're doing a limited launch of a large

Speaker:

but relatively small amount compared to

Speaker:

what the demand is of some really trusted

Speaker:

networks who know both Tyler and I well

Speaker:

and know that we're

Speaker:

going to treat them right.

Speaker:

Because again, even if

Speaker:

everything's great on the machine,

Speaker:

ordering 30,000 machines, selling 10,000

Speaker:

machines a month or something, it's going

Speaker:

to be difficult to scale up enough

Speaker:

service techs like engineers and customer

Speaker:

service and everything to make sure

Speaker:

everyone's getting the experience and the

Speaker:

support that they deserve

Speaker:

and that we want to give them.

Speaker:

So that's why we're doing this soft

Speaker:

launch test order to make sure that we

Speaker:

have the infrastructure enough to scale

Speaker:

up to make sure that everyone is getting

Speaker:

a very high level experience.

Speaker:

Yeah, well, I'll

Speaker:

definitely start saving my pennies.

Speaker:

Just quickly on that one again.

Speaker:

So is this going to be sort of direct to

Speaker:

consumer or do you sort of foresee it

Speaker:

being a sort of a

Speaker:

clinical tool to begin with?

Speaker:

Yeah, so we have a lot of networks of

Speaker:

spas and functional practitioners that

Speaker:

want to be onboarding these, but they'll

Speaker:

also be the direct consumer.

Speaker:

Okay, that's brilliant.

Speaker:

Well, that gives me a bit of hope then.

Speaker:

Alex, I want to be aware of your time, of

Speaker:

course, but I don't think we could have a

Speaker:

conversation about molecular hydrogen

Speaker:

without at least not quickly discussing

Speaker:

hydrogen generators.

Speaker:

Now, as I mentioned earlier, I've

Speaker:

listened to a few past cards you've done

Speaker:

just in preparation for this one.

Speaker:

And I know that they, it's just based on

Speaker:

what you said, the past

Speaker:

that they do seem to struggle.

Speaker:

I know you've mentioned something called

Speaker:

Henry's Law and that there's

Speaker:

an issue with gaskets there.

Speaker:

And the fact that these units can't

Speaker:

necessarily produce the amount of

Speaker:

hydrogen that they do on day one, on

Speaker:

maybe day five or day 10.

Speaker:

Is this something that you

Speaker:

envisage maybe solving yourself?

Speaker:

Is this a problem that

Speaker:

you would like to tackle?

Speaker:

Or is it sort of a bit outside of your

Speaker:

wheelhouse at this point?

Speaker:

So funny enough, I have a patent on a

Speaker:

bottle that uses the

Speaker:

tablet to generate hydrogen

Speaker:

that I developed years ago.

Speaker:

And we knew all these

Speaker:

problems were existed.

Speaker:

And we didn't use Chinese engineers.

Speaker:

We use engineers well

Speaker:

in Canada at the time,

Speaker:

ordered all the parts in, built them

Speaker:

ourselves by hand with

Speaker:

this engineering firm.

Speaker:

What we were getting like concentrated 13

Speaker:

parts per million in these

Speaker:

prototypes we built, right?

Speaker:

So stable, clear, you can drink, we

Speaker:

thought there was going to be great

Speaker:

applications for this, but even getting

Speaker:

gaskets that were rated like five times

Speaker:

higher than what we needed,

Speaker:

not a single one of the units lasted 10

Speaker:

uses before the gaskets were separating.

Speaker:

But even if the gaskets get better, what

Speaker:

we started noticing is the pressure,

Speaker:

because we're getting to 130, 140 PSI of

Speaker:

pressure, it was

Speaker:

starting to unscrew the bolts

Speaker:

from the force.

Speaker:

So we were getting leaking

Speaker:

from all sorts of angles.

Speaker:

And I want to

Speaker:

say that just think about this concept.

Speaker:

This table that my computer is on, maybe

Speaker:

it's rated for 200 pounds.

Speaker:

And say I take a 40 pound weight, and I

Speaker:

drop it from a couple

Speaker:

inches once, table's fine.

Speaker:

But you just keep picking that up and

Speaker:

doing it five times a day, every day.

Speaker:

That reaches a point and not too long

Speaker:

where the table breaks.

Speaker:

Is it a point limit to material fatigue?

Speaker:

Yeah, yeah, exactly.

Speaker:

So this is how these pressurized bottles

Speaker:

work is yes, no matter how

Speaker:

high up you go in the rating,

Speaker:

it's that repeated below

Speaker:

pressure, which eventually breaks.

Speaker:

And just think about how a drop of water

Speaker:

can carve through a mountain,

Speaker:

right?

Speaker:

Just a constant drop over and over.

Speaker:

In time, it will break.

Speaker:

So the question isn't if these machines

Speaker:

can ever not break, they

Speaker:

will always break, right?

Speaker:

It's just how much does it cost to make

Speaker:

sure that they last six months instead of

Speaker:

six days to a couple weeks?

Speaker:

And how much does that cost to do?

Speaker:

So none of these manufacturers seem to

Speaker:

have to be improving on this, which tells

Speaker:

me that to make improvements is going to

Speaker:

drive up the cost so much for not a good

Speaker:

return on longevity.

Speaker:

And like I said,

Speaker:

we were rated, I can't remember, but our

Speaker:

gaskets were rated to something like 750

Speaker:

PSI or something like that.

Speaker:

And still, they all

Speaker:

broke under under 10 uses.

Speaker:

So let me get this right.

Speaker:

So it's a bad solution relative to, say,

Speaker:

the tablets, which have a low barrier to

Speaker:

engine terms and costs have a high yield

Speaker:

in terms of hydrogen that they are.

Speaker:

And they're consistent every time.

Speaker:

So even at their best, these bottles that

Speaker:

are getting up to five parts per million.

Speaker:

Well, that's five parts per million and

Speaker:

typically 250 milliliters.

Speaker:

So that's 1.25 milligrams of each tube.

Speaker:

We're getting 12 parts per million in 500

Speaker:

milliliters if you prepare and drink it

Speaker:

as we suggest, which is

Speaker:

six milligrams of each tube.

Speaker:

So we're getting close to like five times

Speaker:

as much hydrogen when

Speaker:

these bottles are new.

Speaker:

And then all of a sudden, a month later,

Speaker:

now we're getting 30,

Speaker:

40 times more hydrogen.

Speaker:

So even when they're brand new, they are

Speaker:

not getting close to the

Speaker:

dosage that we're getting.

Speaker:

And they break pretty fast.

Speaker:

And not just even if they solve the

Speaker:

gasket issue, there's a secondary issue

Speaker:

of the membranes

Speaker:

slowly start breaking down.

Speaker:

And as they break down, maybe they're

Speaker:

releasing heavy metals.

Speaker:

We don't have the data on that yet.

Speaker:

They're a consumer device.

Speaker:

So they're not legally mandated to post a

Speaker:

long-term safety kind of info like that.

Speaker:

We know that DuPont has put season to

Speaker:

cyst to all the Chinese manufacturers

Speaker:

that they're not allowed to use their

Speaker:

membrane because their membranes aren't

Speaker:

rated for contact with something that's

Speaker:

for human consumption.

Speaker:

So if DuPont is stopping their sales,

Speaker:

saying that this is an intended for human

Speaker:

consumption, that tells

Speaker:

us DuPont knows something.

Speaker:

Or at least to me, it suggests DuPont

Speaker:

might know something that the Chinese

Speaker:

manufacturers don't yet.

Speaker:

So they've almost all switched to their

Speaker:

own membranes now, because DuPont has

Speaker:

removed the ability to use theirs from so

Speaker:

many of these manufacturers.

Speaker:

And those I assume are

Speaker:

questionable as well.

Speaker:

I'd just like to see the data.

Speaker:

I don't want to say definitely this is

Speaker:

going to deliver this or be harmful.

Speaker:

It's just too many questions that I

Speaker:

wouldn't personally use it

Speaker:

until those are answered.

Speaker:

But then the final kicker is to make

Speaker:

these machines, one, you don't want glass

Speaker:

because that becomes a bomb or shrapnel.

Speaker:

So you have to use plastic.

Speaker:

And then with this repeated

Speaker:

pressurization over and over again, how

Speaker:

many microplastics and PFAS are you

Speaker:

getting into the water?

Speaker:

So that's another question.

Speaker:

Yeah, definitely.

Speaker:

Like I said, I think it's just finding a

Speaker:

complex solution to a problem that

Speaker:

already has a simple

Speaker:

answer, in this case, tablets.

Speaker:

Alex, you've been amazing truly, and

Speaker:

maybe it's just me, but I get way more

Speaker:

starstruck talking to someone like you

Speaker:

than I ever would a Tom Cruise type.

Speaker:

Before I let you go, though, and I do

Speaker:

need to let you go, I'm aware of that,

Speaker:

would you be okay if we just ran through

Speaker:

a few rapidish fire questions quickly?

Speaker:

Yeah.

Speaker:

Okay, brilliant.

Speaker:

Thank you.

Speaker:

All right.

Speaker:

So just off the bat,

Speaker:

you mentioned this a second ago, but

Speaker:

what's the best way to

Speaker:

use molecular hydrogen pads?

Speaker:

I think that the best way is

Speaker:

one, room temperature water.

Speaker:

I designed it for room temperature water.

Speaker:

Now, the reason for that is we can't

Speaker:

really guzzle or chug

Speaker:

cold water or hot water.

Speaker:

So we designed it to react ideally in

Speaker:

room temperature water.

Speaker:

You don't want it to be highly alkaline

Speaker:

and not distilled either.

Speaker:

So you want a little bit of electrolytes

Speaker:

like TDS in the water, but really

Speaker:

anywhere from three parts per million to

Speaker:

200 parts per million.

Speaker:

So basically every bottled water on the

Speaker:

market and every re mineralizing RO

Speaker:

system and every tap water source other

Speaker:

than if you're in a well with super hard

Speaker:

water is going to work fine.

Speaker:

Just don't use alkaline ionized water or

Speaker:

highly alkaline mineral water.

Speaker:

Don't use carbonated water, which I know

Speaker:

is a lot more popular in the UK and

Speaker:

Europe than here because then the

Speaker:

hydrogen is competing with the CO2 for

Speaker:

partial pressure and the CO2

Speaker:

wins and it sparges out the H2.

Speaker:

That would screw with the

Speaker:

zeta potential, is that right?

Speaker:

Yeah, so I mean, one, it's going to

Speaker:

disrupt H2, only so much can stay in.

Speaker:

It's not going to allow saturated H2.

Speaker:

There's going to be more collisions which

Speaker:

increases the bubble size

Speaker:

of the quasi dissolved H2.

Speaker:

So it's just going to

Speaker:

lead to a bad result.

Speaker:

I'd say 500 milliliters is what we

Speaker:

designed this for, but the best volume of

Speaker:

water is what you can guzzle rapidly.

Speaker:

So for instance, in the elderly trials,

Speaker:

we use 250 milliliters and most of the

Speaker:

middle aged like metabolic

Speaker:

trials, we use 330 milliliters.

Speaker:

So I guzzle a liter first thing in the

Speaker:

morning, but I'm a big guy and so

Speaker:

exercise a lot and I can chug a liter

Speaker:

first thing in the morning

Speaker:

with a lot of my supplements.

Speaker:

Most people can't.

Speaker:

So I put a few tablets in a

Speaker:

liter and then chug it down.

Speaker:

But again, most people can't do that.

Speaker:

I will say you want to

Speaker:

take it on an empty stomach.

Speaker:

I do have IP demonstrating that hydrogen

Speaker:

in an aqueous solution that has dissolved

Speaker:

polysaccharides retains the H2

Speaker:

nanobubbles and creates gels and foams.

Speaker:

So that's going to

Speaker:

happen in your stomach.

Speaker:

And actually there is data like someone

Speaker:

unaware of my pending IP at the time

Speaker:

about this made these

Speaker:

hydrogen rich like jello.

Speaker:

It was a physicist in Vegas that I ended

Speaker:

up talking to a bunch and he dropped the

Speaker:

project because he found out about my IP.

Speaker:

But they were measuring the hydrogen

Speaker:

leaving in the urine after.

Speaker:

I'm like, well, if it's all leaving in

Speaker:

the urine, then it's not

Speaker:

circulating in your body.

Speaker:

So hydrogen works by

Speaker:

like other hermetic stressors, you want

Speaker:

this spike and then

Speaker:

this return to baseline.

Speaker:

So you want to peak in a valley.

Speaker:

So you don't want to eat it with a meal

Speaker:

heavy and like carbohydrates or fiber

Speaker:

because they're going to retain the H2

Speaker:

and it's not going to hit that rapid

Speaker:

spike into yourselves.

Speaker:

Yeah, definitely.

Speaker:

Next one.

Speaker:

Have you ever thrown down a tablet down

Speaker:

the hatch and then

Speaker:

chased it down with water?

Speaker:

Have you sort of ever done that?

Speaker:

So I have, I don't recommend it because I

Speaker:

have when I'm in a rush, I know Dr.

Speaker:

LaBaron talks about it.

Speaker:

He does it when he's in an absolute rush

Speaker:

and doesn't like he's late walking up the

Speaker:

door, I'm late walking up the door and I

Speaker:

don't have like a minute to spare.

Speaker:

Why you wouldn't want to do that is if

Speaker:

you don't drink enough water, right?

Speaker:

And then you might get some

Speaker:

unpleasantness in your gut.

Speaker:

So we can't recommend that.

Speaker:

People are really, really bad at judging

Speaker:

what enough water is.

Speaker:

You know, I see even

Speaker:

when I see people like,

Speaker:

even people I'm friends with or family

Speaker:

members, I'll see them drop like a tablet

Speaker:

in like 50 milliliters of water.

Speaker:

And I'm like, what do you

Speaker:

think is going on there?

Speaker:

Like, you know, stop doing that.

Speaker:

Right.

Speaker:

So I see that and know that if I tell

Speaker:

people, yeah, you can swallow it and

Speaker:

chase it with water, they're going to

Speaker:

swallow the tablet and take a sip.

Speaker:

Right.

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And now that's not nearly enough water.

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So you're not going to get

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the same therapeutic effect.

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But moreover, you're going to potentially

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make your stomach upset.

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Right.

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And long term use of that, maybe you're

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going to develop an ulcer or something.

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So don't do that.

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I mean, there is a way to do it safely,

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but there's not a way to advise it to

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people who are going to listen and do it

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safely, if that makes sense.

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Yeah.

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Is any, sorry, quick tangent on that one.

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Is any exothermic

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reaction or heat developed?

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That would also be an issue, I'd imagine.

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Okay.

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Moving on quickly then.

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Besides molecular hydrogen, what single

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molecule excites you the most when it

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comes to supporting health,

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supporting human longevity?

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That's in the pipeline, perhaps, or

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something that may already exist.

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Yeah.

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I mean, I know we've

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talked about Tessa Fencine.

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I really like that molecule.

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I'm getting it off the black market.

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I basically quit drinking and have no

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desire to drink alcohol

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since I started Tessa Fencine.

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I have much less cravings for food.

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Other than that, it's hard

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to pinpoint a single molecule.

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I probably take 100 pills a day, and then

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liters of supplemental liquids and stuff.

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So it's really, really difficult to

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pinpoint one thing, and

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especially with everything,

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it depends on the context.

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For instance,

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something like methyl folate.

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When I was getting off Tessa ulcerin

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replacement and trying

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to regain my fertility,

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high dose methyl folate, like five

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milligrams a day, has been linked to

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improving male fertility.

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But you only want to do that for a month

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or two, because if you're doing that long

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term and you're not

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countering it with other B-wedding...

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Yeah.

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I mean, because

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absolutely, with something like TMG.

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Too many methyl donors.

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Yeah.

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All right.

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It's going to lead to some problems.

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Definitely.

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I mean, the moment you start playing

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around with the methyl folate cycle, the

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folate cycle, you've got to be careful

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and you've got to have an understanding

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of your genetics as well.

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Okay.

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So I'll skip one.

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And the final question is, what's the

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next for you on the health front?

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Obviously, you've been through this

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journey, and I know

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there's still a long way to go.

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I think you said you were a candidate for

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a few different operations.

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What is next to you in terms of you

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trying to optimize your health, if you

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don't mind me asking?

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So with me, it's always

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just trying to improve.

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And I've been getting

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rounds of stem cells.

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They've helped a little bit.

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I need to keep doing that.

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I'm really actually excited about some

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other protocols that we're seeing in

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rodents, but haven't

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jumped to humans yet.

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There's protocols where they're doing

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micro drilling into joints, even if

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there's just very small pieces of it and

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injecting them not just with stem cells,

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but various peptides and

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block building molecules.

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They're able to completely

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regrow joints in rodents now.

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But there isn't even the highest end

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clinic in the world that's trying these

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protocols in humans.

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So I'd say that is something I am

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desperately looking forward to, to try

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and actually regrow the

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joints that I've lost.

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Yeah, I can only imagine.

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Alex, you've been a star.

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Truly, I appreciate this

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conversation more than you know.

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Where can people find you if they do want

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to learn more about you, if they do not

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want to learn more

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about hydrogen tablets?

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I assume you would point them to HRW.

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And then I know we mentioned it earlier,

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but just yet, plug your

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book that's coming out shortly.

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Yeah, so alexternava.com is my website.

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My Instagram is the same at Alexternava.

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I have a ResearchGate account that you

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can read some of the papers that I've

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published or co-authored on.

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Again, it's Alexternava, my ResearchGate.

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For the tablets, I mean, I

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supply to like 100 brands

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with the Trink HRW.

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I've written a lot of

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blog content for them.

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There's a lot of good content I wrote.

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Some of it is pretty dated.

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I would have written it four or five,

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six, seven years ago.

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But even the dated stuff

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is still mostly accurate.

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There's just new information that could

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be rewritten, but that's

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really on them to update it.

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I can't be rewriting

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stuff for them forever.

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But yeah, those would be the best spots.

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If you're on my social media or on my

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website, you'll see the new podcast

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editions that go live.

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You'll get announcements

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from my books as they're coming.

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So I actually released one book, but then

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I read it after it had gone

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through the editing process.

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And I learned a lot because I had

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approved every

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paragraph that was being edited.

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But just looking at the paragraph through

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kind of like a keyhole,

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and I didn't think to

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read it chronologically.

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And then it came out and then I pulled it

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because I started

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reading it chronologically.

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I'm like, oh man, this is lost nuance.

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It's changed my voice.

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It's a little repetitive.

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So I pulled it.

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That's being rewritten.

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But actually, I think it's more fitting

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because the book that I wanted to release

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first, Stress Hacked, I was going to

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release second because the final thought

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war was complete and Stress Hacked was

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only about 90% complete

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when I made this decision.

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But now Stress Hacked is

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complete going through editing.

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So now I'm having to redo the editing of

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the final thought war.

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So they're going to get reversed, which I

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originally wanted it that way anyways.

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But I've written to various levels of

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finished seven books right now.

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So they'll be slowly

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released over the next few years.

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That's impressive.

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I'll definitely be getting

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every single one of them.

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And as I mentioned during our sort of

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initial

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correspondence, that's impressive.

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So I'm still trying to come

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up with the concept for one.

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Alex, again, thank you

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so much for your time.

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This was, again, at the risk of being the

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most truly a pleasure.

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And I'm just grateful for the opportunity

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to talk to you this morning.

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Awesome.

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Yeah.

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Thank you very much for having me.