Welcome to the VP
Speaker:Live podcast, the
Speaker:show where we
Speaker:bring you
Speaker:actionable health
Speaker:advice for
Speaker:revealing minds.
Speaker:I'm your
Speaker:host, Rob.
Speaker:My guest today is
Speaker:Justin McGuire, a
Speaker:South
Speaker:African-based
Speaker:holistic health
Speaker:and performance
Speaker:coach who works
Speaker:with clients to
Speaker:help them
Speaker:optimize all
Speaker:aspects of their
Speaker:health and lives.
Speaker:Today's
Speaker:conversation
Speaker:centers around
Speaker:how the immune
Speaker:system ultimately
Speaker:governs
Speaker:metabolism.
Speaker:And while we
Speaker:certainly get
Speaker:into the weeds
Speaker:today, I really
Speaker:encourage you to
Speaker:listen through,
Speaker:as the
Speaker:information
Speaker:Justin provides
Speaker:is nothing short
Speaker:of pure gold.
Speaker:Expect to learn
Speaker:how the immune
Speaker:system actually
Speaker:operates, why
Speaker:chronic
Speaker:inflammation
Speaker:might actually be
Speaker:the cause of
Speaker:weight gain in so
Speaker:many populations,
Speaker:and Justin's top
Speaker:picks for
Speaker:nutrients that
Speaker:help to improve
Speaker:immune system
Speaker:function.
Speaker:Now, on to the
Speaker:conversation with
Speaker:Justin McGuire.
Speaker:Hey, Justin,
Speaker:thanks for
Speaker:being here.
Speaker:We've rubbed
Speaker:shoulders over
Speaker:the years, but
Speaker:we've never
Speaker:really sat down
Speaker:to have a
Speaker:conversation
Speaker:as such.
Speaker:So I'm excited to
Speaker:have this
Speaker:opportunity to
Speaker:pick your brain
Speaker:on this topic,
Speaker:which is
Speaker:something I'm
Speaker:becoming more and
Speaker:more passionate
Speaker:about by the day.
Speaker:And that's this
Speaker:concept of
Speaker:immunomatabolism.
Speaker:The idea, loosely
Speaker:speaking, that
Speaker:the metabolism is
Speaker:mediated, to some
Speaker:degree, by the
Speaker:immune system and
Speaker:vice versa.
Speaker:And again, just
Speaker:the idea that
Speaker:subsequently a
Speaker:lot of disease
Speaker:can be viewed
Speaker:through this lens
Speaker:and potentially
Speaker:solved through
Speaker:this lens
Speaker:as well.
Speaker:I know for the
Speaker:listeners that
Speaker:that probably
Speaker:sounds pretty
Speaker:convoluted, but I
Speaker:promise we'll
Speaker:break it down
Speaker:shortly.
Speaker:First, though,
Speaker:I'd love to learn
Speaker:a little more
Speaker:about you.
Speaker:I know through
Speaker:something of your
Speaker:story, through
Speaker:our mutual friend
Speaker:Ben Law, that
Speaker:beyond that, I'm
Speaker:ashamed to say I
Speaker:don't actually
Speaker:know too much
Speaker:about your
Speaker:backstory, but
Speaker:I'd love to
Speaker:understand a bit
Speaker:more about how
Speaker:you ended up in
Speaker:this sort of
Speaker:integrative
Speaker:health and
Speaker:performance
Speaker:space.
Speaker:It's good
Speaker:to be here.
Speaker:Thank you, Rob.
Speaker:Looking forward
Speaker:to sharing some
Speaker:insight.
Speaker:So my story is an
Speaker:interesting one.
Speaker:I just actually
Speaker:had a
Speaker:conversation with
Speaker:one of my
Speaker:metaphysicians.
Speaker:And yes, I'm
Speaker:probably the most
Speaker:hippie scientist
Speaker:you're ever going
Speaker:to come across.
Speaker:And in our
Speaker:conversation this
Speaker:morning, it was
Speaker:the fact that
Speaker:I've literally
Speaker:gone through four
Speaker:major personas
Speaker:just during this
Speaker:one single
Speaker:lifetime itself.
Speaker:So my previous
Speaker:persona narrative
Speaker:was very
Speaker:different as
Speaker:opposed to whom I
Speaker:am now today.
Speaker:And I think this
Speaker:can, many people,
Speaker:not many, but
Speaker:some may attest
Speaker:to having
Speaker:experienced the
Speaker:contrast of self.
Speaker:So my former life
Speaker:in my 20s and my
Speaker:teens, I was
Speaker:competitive in
Speaker:the fitness world
Speaker:and bodybuilding
Speaker:and martial arts
Speaker:and so on.
Speaker:I was a personal
Speaker:trainer.
Speaker:And it served
Speaker:purpose
Speaker:for a while.
Speaker:However, it
Speaker:didn't provide me
Speaker:with the mental
Speaker:stimulus that I
Speaker:inherently was
Speaker:craving.
Speaker:Suffice to say,
Speaker:like a soul,
Speaker:well, again,
Speaker:maybe not like a
Speaker:soul, these
Speaker:definitive
Speaker:statements really
Speaker:get me sometimes.
Speaker:And the more
Speaker:conscious you
Speaker:become, the more
Speaker:aware you are of
Speaker:the words you
Speaker:choose to use.
Speaker:For some of us,
Speaker:we go through
Speaker:dark nights of
Speaker:assault, some of
Speaker:which are
Speaker:self-inflicted in
Speaker:terms of the
Speaker:sequence of
Speaker:events that
Speaker:lead to it.
Speaker:Others are
Speaker:inflicted
Speaker:upon us.
Speaker:But for whatever
Speaker:reason it is that
Speaker:we, or however it
Speaker:is that we end up
Speaker:there, we go
Speaker:through a moment
Speaker:of reflection.
Speaker:So that happened
Speaker:in my 30th and
Speaker:31st year,
Speaker:between the 30
Speaker:and the 31st year
Speaker:of my life.
Speaker:And then shortly
Speaker:thereafter,
Speaker:having gone
Speaker:through that very
Speaker:extreme moment in
Speaker:my life, of which
Speaker:the majority of
Speaker:it was actually
Speaker:impacted by my
Speaker:own poor
Speaker:decisions,
Speaker:admittedly.
Speaker:But not knowing
Speaker:as to, at that
Speaker:time in my life,
Speaker:not knowing as to
Speaker:why it is that I
Speaker:had a propensity
Speaker:to create, to
Speaker:have, to choose
Speaker:wrongly.
Speaker:And only later on
Speaker:that I started to
Speaker:discover that
Speaker:there were so
Speaker:many more layers
Speaker:into the
Speaker:complexity of
Speaker:life,
Speaker:particularly our
Speaker:lives, that can
Speaker:influence one's
Speaker:perception and
Speaker:thus one's own
Speaker:personal
Speaker:identity.
Speaker:And when we are
Speaker:in a state of
Speaker:water pilot, and
Speaker:particularly if
Speaker:we're not
Speaker:self-conscious,
Speaker:we're not
Speaker:conscious of
Speaker:self, not
Speaker:self-conscious,
Speaker:we're not
Speaker:conscious of
Speaker:self, it can lead
Speaker:us astray.
Speaker:So in any case, I
Speaker:would let myself
Speaker:astray based upon
Speaker:a whole lot of
Speaker:variables that
Speaker:are unnecessary
Speaker:to divulge into,
Speaker:because it's not
Speaker:about what led
Speaker:you there, it's
Speaker:the fact that it
Speaker:happened, and
Speaker:what are you
Speaker:gonna do
Speaker:about it?
Speaker:Where taking
Speaker:responsibility
Speaker:requires letting
Speaker:go of things that
Speaker:got you there,
Speaker:but taking full
Speaker:hold of what it
Speaker:is that you were,
Speaker:or what it is
Speaker:that you are, and
Speaker:wanting to
Speaker:change, unless
Speaker:you don't
Speaker:want to change.
Speaker:And if life is
Speaker:going the right
Speaker:direction, I want
Speaker:me to keep on
Speaker:doing what it is
Speaker:that you feel
Speaker:necessary, but
Speaker:mine wasn't.
Speaker:And I was
Speaker:confronted with
Speaker:an opportunity to
Speaker:either pass away,
Speaker:because
Speaker:literally, that's
Speaker:how thin my
Speaker:lifeline was, or
Speaker:to make a change.
Speaker:And I made a
Speaker:change, and
Speaker:subsequently
Speaker:making a change,
Speaker:and the universe
Speaker:really threw a
Speaker:spanner into the
Speaker:works and
Speaker:challenged me to
Speaker:yet
Speaker:another degree.
Speaker:And about 18
Speaker:months after I'd
Speaker:made a change,
Speaker:I went through a
Speaker:bit of a depth,
Speaker:an emotional
Speaker:depth that
Speaker:resulted in a...
Speaker:What happens when
Speaker:you've been
Speaker:sober, and then
Speaker:you slip up?
Speaker:Oh, come on, it's
Speaker:such a
Speaker:simple word.
Speaker:Uh, this is like
Speaker:the blind,
Speaker:in the blind.
Speaker:Relapse, relapse,
Speaker:relapse.
Speaker:Gosh, it's just
Speaker:the simplest
Speaker:words, right?
Speaker:It's just funny.
Speaker:So it resulted,
Speaker:this is what
Speaker:happens off the
Speaker:COVID, right?
Speaker:It's like all the
Speaker:complex words, no
Speaker:problem, but the
Speaker:simple things of
Speaker:joining krumjags
Speaker:is like really
Speaker:the word you
Speaker:wanna...
Speaker:And perhaps I've
Speaker:blocked it out of
Speaker:my psyche, to
Speaker:some
Speaker:extent, as well.
Speaker:Yeah, this is
Speaker:where you just
Speaker:eat all the urode
Speaker:monophosphate and
Speaker:just pray, yeah,
Speaker:and I can
Speaker:understand that.
Speaker:(Laughing) So anyway, it
Speaker:resulted in a
Speaker:relapse.
Speaker:And in that
Speaker:relapse, I had
Speaker:to, once again,
Speaker:revisit what it
Speaker:was that I had
Speaker:not been
Speaker:addressing.
Speaker:And I think as
Speaker:many men, from
Speaker:our generation at
Speaker:least, and
Speaker:generations
Speaker:prior, we were
Speaker:taught to pretty
Speaker:much suppress the
Speaker:expression of
Speaker:emotions and to
Speaker:just
Speaker:tough it out.
Speaker:Blood-swayed
Speaker:interiors is the
Speaker:motto of our
Speaker:generation.
Speaker:So yeah, with
Speaker:that, just the
Speaker:avoidance sets
Speaker:in, right?
Speaker:So you'll find
Speaker:elaborate ways to
Speaker:avoid what's
Speaker:actually going on
Speaker:within yourself,
Speaker:particularly by
Speaker:way of expression
Speaker:of ego, which
Speaker:didn't help much,
Speaker:I'm grateful for
Speaker:my body, which
Speaker:that's
Speaker:like I have.
Speaker:But in being able
Speaker:to build muscle
Speaker:quite quickly, I
Speaker:was able to build
Speaker:up a persona and
Speaker:ego to avoid a
Speaker:lot of things
Speaker:really
Speaker:easily as well.
Speaker:(Laughing) So, and see
Speaker:whether the
Speaker:relapse happened,
Speaker:came out of that,
Speaker:and things then
Speaker:really started to
Speaker:settle for me,
Speaker:like really
Speaker:started to shift.
Speaker:The foundation
Speaker:started to shift
Speaker:into a whole new
Speaker:dimension of
Speaker:self-experience.
Speaker:And then
Speaker:subsequently, I
Speaker:was doing really
Speaker:well, and then
Speaker:literally six
Speaker:months
Speaker:thereafter, yet
Speaker:another layer of
Speaker:complexity.
Speaker:The universe is
Speaker:like, okay, you
Speaker:ready for the
Speaker:next test?
Speaker:You ready for the
Speaker:next test?
Speaker:You ready for the
Speaker:next test?
Speaker:And then I
Speaker:developed
Speaker:Polymalgeoromatica.
Speaker:Now this is an
Speaker:autoimmune
Speaker:disease that
Speaker:mostly afflicts
Speaker:people over the
Speaker:age of 55.
Speaker:It's an extreme
Speaker:debilitating
Speaker:autoimmune
Speaker:condition, this
Speaker:chronic low grade
Speaker:inflammation that
Speaker:impacts not only
Speaker:pain in the body,
Speaker:but also causes a
Speaker:lot of
Speaker:neuroinflammatory
Speaker:outcomes and
Speaker:symptoms.
Speaker:So I went to
Speaker:every specialist,
Speaker:I mean, I spent
Speaker:money that I
Speaker:didn't have to
Speaker:try and get into
Speaker:the best
Speaker:specialist.
Speaker:And 12th of the
Speaker:best specialists
Speaker:in the country
Speaker:later, I was told
Speaker:it's all
Speaker:psychosomatic.
Speaker:Now, I mean, the
Speaker:intensity of the
Speaker:pain was so bad
Speaker:that I literally
Speaker:couldn't sleep
Speaker:for three or five
Speaker:days at a time.
Speaker:So it had three
Speaker:or five days of
Speaker:perpetual
Speaker:insomnia.
Speaker:Long story short,
Speaker:this sounds like
Speaker:a big dramatic
Speaker:narrative, and I
Speaker:would actually
Speaker:cut it short
Speaker:because it's not
Speaker:about that.
Speaker:It's about what
Speaker:it actually
Speaker:taught me.
Speaker:And what it
Speaker:taught me is
Speaker:that, no matter
Speaker:how good the
Speaker:intention of the
Speaker:person, because I
Speaker:don't believe any
Speaker:of these
Speaker:specialists, and
Speaker:this is where the
Speaker:polarity of
Speaker:fitness
Speaker:communities or
Speaker:biohacking
Speaker:communities or
Speaker:precision
Speaker:medicine or
Speaker:functional
Speaker:medicine
Speaker:communities can
Speaker:really lead
Speaker:people astray.
Speaker:Doctors are not
Speaker:at fault.
Speaker:I'm gonna make
Speaker:the statement
Speaker:right there.
Speaker:Doctors are not
Speaker:at fault.
Speaker:Like to get into
Speaker:medical school,
Speaker:do you know how
Speaker:much discipline
Speaker:and dedication it
Speaker:requires?
Speaker:Literally
Speaker:finishing it.
Speaker:It's not the
Speaker:intention of
Speaker:these individuals
Speaker:to not
Speaker:help people.
Speaker:It's actually the
Speaker:intention to be
Speaker:of service.
Speaker:It's the
Speaker:institution that
Speaker:is the problem.
Speaker:And the
Speaker:institution has
Speaker:led people astray
Speaker:into
Speaker:compartmentalizing
Speaker:their health.
Speaker:And because I
Speaker:wasn't able to be
Speaker:fit in, because
Speaker:they weren't able
Speaker:to fit me
Speaker:into a box.
Speaker:Paradigm, yeah.
Speaker:Into a paradigm,
Speaker:I became the
Speaker:psychosomatic
Speaker:patient.
Speaker:Despite all the
Speaker:symptoms that
Speaker:we're saying
Speaker:otherwise.
Speaker:Yes, most
Speaker:certainly there
Speaker:is some truth to
Speaker:that as well.
Speaker:I won't say that
Speaker:they were
Speaker:entirely wrong.
Speaker:There is most
Speaker:certainly some
Speaker:truth to it.
Speaker:But the truth
Speaker:came in that,
Speaker:yes, there were
Speaker:some psycho,
Speaker:there were many,
Speaker:not some, there
Speaker:were many
Speaker:psychological
Speaker:traumas that were
Speaker:coming up to the
Speaker:surface, which
Speaker:were expressing
Speaker:themselves
Speaker:on my body.
Speaker:I didn't know
Speaker:this at the time.
Speaker:I mean, this is
Speaker:like, you know, I
Speaker:was a bodybuilder
Speaker:two years prior
Speaker:to that.
Speaker:Competing, sorry,
Speaker:a year
Speaker:prior to that.
Speaker:I had done my
Speaker:last
Speaker:bodybuilding show.
Speaker:So I was in that
Speaker:whole fitness
Speaker:community, like,
Speaker:you know, Grant
Speaker:Go, Grant and Go,
Speaker:5am Club, you
Speaker:know, Hell's
Speaker:Bells, off
Speaker:your squat.
Speaker:So I don't really
Speaker:know like, you
Speaker:know, like the
Speaker:somatic impact
Speaker:that can happen
Speaker:from emotional
Speaker:response.
Speaker:I mean, I heard
Speaker:of it, but I kind
Speaker:of, to be honest
Speaker:with you, I
Speaker:thought it was a
Speaker:bit of a hogwash.
Speaker:I thought it was
Speaker:like, it's the
Speaker:things that
Speaker:esoteric believe
Speaker:in kind of
Speaker:thing, right?
Speaker:But a little bit,
Speaker:I know how
Speaker:truthful that
Speaker:actually was.
Speaker:So much
Speaker:truth to it.
Speaker:So it went wrong
Speaker:that it was part,
Speaker:it had
Speaker:psychosomatic,
Speaker:there was certain
Speaker:elements of
Speaker:psychosomatic
Speaker:contribution
Speaker:toward my state.
Speaker:But this is where
Speaker:like, again, in
Speaker:the human
Speaker:dualistic
Speaker:perceptive
Speaker:paradigm, we
Speaker:separate things.
Speaker:We forget that
Speaker:there's actually
Speaker:continuity in
Speaker:everything.
Speaker:And this is where
Speaker:one of my
Speaker:favorite writings
Speaker:of all time, it's
Speaker:actually an
Speaker:essay, it's not a
Speaker:book by Antoine
Speaker:Fabre de la Vie,
Speaker:and he wrote his
Speaker:essay in the
Speaker:late 1700s.
Speaker:And the essay is
Speaker:entitled, "The
Speaker:Metaphysical and
Speaker:Intellectual
Speaker:Constitution
Speaker:of Man."
Speaker:Within this
Speaker:essay, he has a
Speaker:graphical
Speaker:depiction of the
Speaker:intersection.
Speaker:Within his
Speaker:semantics, he
Speaker:doesn't use mind,
Speaker:body and soul, he
Speaker:uses soul, spirit
Speaker:and body.
Speaker:But basically
Speaker:they depict what
Speaker:we understand to
Speaker:be mind, body and
Speaker:soul, and the
Speaker:difference of
Speaker:emotional
Speaker:intersect that
Speaker:can happen
Speaker:depending upon
Speaker:where we are in
Speaker:our state of
Speaker:consciousness,
Speaker:whether it is
Speaker:more so in the
Speaker:anima, the
Speaker:animus, or
Speaker:whether it's more
Speaker:in God
Speaker:consciousness and
Speaker:everything in
Speaker:between.
Speaker:So in looking at
Speaker:that model,
Speaker:knowing that
Speaker:whatever happens
Speaker:to the mind
Speaker:happens to the
Speaker:body, certainly,
Speaker:but whatever's
Speaker:happening to the
Speaker:body can
Speaker:perpetuate what's
Speaker:happening in the
Speaker:mind as well.
Speaker:And this is one
Speaker:of the first big
Speaker:pieces of the
Speaker:puzzle that came
Speaker:together.
Speaker:I had probably,
Speaker:I had done it on
Speaker:my own, because I
Speaker:didn't
Speaker:have any help.
Speaker:I went to
Speaker:everybody and
Speaker:they put me on
Speaker:pregnancy zone
Speaker:and they put me
Speaker:on
Speaker:anti-psychotics
Speaker:and everything
Speaker:else, which just
Speaker:made me worse.
Speaker:Yeah, so as I was
Speaker:saying, so I
Speaker:didn't have
Speaker:pretty much any
Speaker:help from the
Speaker:specialists,
Speaker:although they had
Speaker:good attention,
Speaker:they weren't able
Speaker:to fit me into a
Speaker:model, into
Speaker:like a mold.
Speaker:So I had to
Speaker:pretty much
Speaker:figure myself
Speaker:out, which was
Speaker:quite
Speaker:frustrating,
Speaker:because you look
Speaker:into my
Speaker:historical
Speaker:education behind
Speaker:biochemistry,
Speaker:which I had a
Speaker:very basic
Speaker:biochemical, I
Speaker:mean, it was
Speaker:self-taught in
Speaker:the early part of
Speaker:my, I later on
Speaker:got degrees, in
Speaker:my thirties
Speaker:subsequently
Speaker:after this, I got
Speaker:foundation
Speaker:degrees and then
Speaker:I got a
Speaker:bachelor's and so
Speaker:on at Biochem.
Speaker:But in my
Speaker:twenties, it's
Speaker:very basic.
Speaker:And I thought I
Speaker:had to basically
Speaker:start my whole
Speaker:journey in
Speaker:front of it.
Speaker:But anyway, long
Speaker:story short, when
Speaker:the student is
Speaker:ready, the
Speaker:teacher will
Speaker:appear, and along
Speaker:my journey, I
Speaker:started to be, I
Speaker:was introduced to
Speaker:certain function
Speaker:medicine doctors,
Speaker:integrated
Speaker:medicine doctors,
Speaker:all of which
Speaker:actually provided
Speaker:educational
Speaker:resources as
Speaker:well, which I put
Speaker:myself through,
Speaker:when I had the
Speaker:financial reasons
Speaker:to do so, which
Speaker:was quite tough.
Speaker:I mean, as you
Speaker:probably are
Speaker:aware of, having
Speaker:had long haul
Speaker:COVID-19 for two
Speaker:years, it's
Speaker:really difficult
Speaker:to manage earning
Speaker:a living whilst
Speaker:being chronically
Speaker:fatigued, right?
Speaker:And brain fog to
Speaker:boot on top of
Speaker:that, let alone
Speaker:the physical pain
Speaker:that can also
Speaker:sporadically
Speaker:creep in when
Speaker:there's not
Speaker:enough cortisol
Speaker:to mitigate the
Speaker:inflammation.
Speaker:So I did what I
Speaker:could, and it was
Speaker:a journey.
Speaker:It was probably
Speaker:the best PhD I've
Speaker:ever earned in
Speaker:life going
Speaker:through that
Speaker:journey,
Speaker:which birthed the
Speaker:opportunity to
Speaker:start autonomic
Speaker:coaching.
Speaker:And autonomic
Speaker:coaching is a
Speaker:conceptual birth
Speaker:child of mine,
Speaker:within which I
Speaker:truly am trying
Speaker:to continue to
Speaker:expand a honest
Speaker:interdisciplinary
Speaker:approach.
Speaker:Because again, I
Speaker:just wanna
Speaker:emphasize,
Speaker:doctors are not
Speaker:at fault.
Speaker:You can't blame,
Speaker:it's like putting
Speaker:somebody in a
Speaker:label and saying
Speaker:because they put
Speaker:11 years of their
Speaker:life into
Speaker:educating
Speaker:themselves to do
Speaker:a certain
Speaker:discipline, now
Speaker:they're evil.
Speaker:Like where's the
Speaker:logic of that?
Speaker:They're
Speaker:not at fault.
Speaker:It's just that
Speaker:there are many
Speaker:other ways apart
Speaker:from allopathy as
Speaker:to how one can
Speaker:approach
Speaker:remedying for
Speaker:health, okay?
Speaker:And this is where
Speaker:autonomic
Speaker:coaching comes
Speaker:in, and we
Speaker:provide
Speaker:allopathic
Speaker:support, we
Speaker:provide
Speaker:naturopathic
Speaker:support, we
Speaker:provide
Speaker:psychological
Speaker:support, we
Speaker:provide lifestyle
Speaker:coaching as well.
Speaker:So it's the whole
Speaker:kitchen computer,
Speaker:the whole
Speaker:paradigm to
Speaker:support the
Speaker:individual.
Speaker:This is where
Speaker:inductive
Speaker:reasoning is, we
Speaker:are able to
Speaker:enable inductive
Speaker:reasoning within
Speaker:this paradigm.
Speaker:You know,
Speaker:evidence-based
Speaker:medicine is based
Speaker:on the reductive
Speaker:model so that one
Speaker:can take
Speaker:deductive
Speaker:outcomes from it,
Speaker:which is great
Speaker:for the populace,
Speaker:for the masses.
Speaker:But there's a
Speaker:shortfall within
Speaker:the outliers of
Speaker:those who don't
Speaker:fit into
Speaker:the mold.
Speaker:And this is where
Speaker:inductive
Speaker:reasoning
Speaker:comes in.
Speaker:So most of the
Speaker:people that come
Speaker:to see us,
Speaker:come to see us
Speaker:after they've
Speaker:been to many
Speaker:different
Speaker:practitioners,
Speaker:alternative as
Speaker:well as
Speaker:conventional, and
Speaker:they just haven't
Speaker:gotten
Speaker:the result.
Speaker:That they, well,
Speaker:they haven't been
Speaker:given their
Speaker:life back.
Speaker:Do we help, are
Speaker:we successful
Speaker:with all of those
Speaker:we help?
Speaker:No, we're not,
Speaker:but are we
Speaker:successful with the
Speaker:majority of them?
Speaker:Yes, we are.
Speaker:And those who
Speaker:we're not
Speaker:successful with,
Speaker:we have got an
Speaker:extensive network
Speaker:that we are able
Speaker:to get solutions
Speaker:to people.
Speaker:And this is, the
Speaker:reason why I'm
Speaker:also putting this
Speaker:out there is to
Speaker:not allude anyone
Speaker:to the idea that
Speaker:we are the
Speaker:holy grail.
Speaker:Okay, there is no
Speaker:such thing.
Speaker:If something
Speaker:doesn't work with
Speaker:a certain
Speaker:specialist or a
Speaker:certain thought
Speaker:process, don't
Speaker:give up.
Speaker:That's the
Speaker:message I'm
Speaker:trying to
Speaker:put out there.
Speaker:If anybody is
Speaker:growing through a
Speaker:tough time and
Speaker:they've tried
Speaker:everything, which
Speaker:is impossible, is
Speaker:to try everything
Speaker:you need multiple
Speaker:lifetimes.
Speaker:Okay,
Speaker:don't give up.
Speaker:Like, have faith
Speaker:and truly like
Speaker:the power of, I'm
Speaker:not religious,
Speaker:but I'm very
Speaker:spiritual.
Speaker:And whether you
Speaker:are or you're
Speaker:not, I think it's
Speaker:irrelevant to the
Speaker:question.
Speaker:Sometimes this
Speaker:process is a
Speaker:process of
Speaker:positive
Speaker:introspection,
Speaker:positive
Speaker:psychology can
Speaker:really shift the
Speaker:narrative of
Speaker:where it is that
Speaker:you're willing to
Speaker:invest your
Speaker:energy into.
Speaker:So yes, we
Speaker:help most.
Speaker:Do we help
Speaker:everyone know?
Speaker:But that doesn't
Speaker:mean that there
Speaker:isn't a solution
Speaker:for everybody.
Speaker:And I think as a
Speaker:community of
Speaker:professionals,
Speaker:health
Speaker:professionals,
Speaker:we're making, as
Speaker:we are coming
Speaker:together more and
Speaker:more so, like
Speaker:every year I see
Speaker:that there's
Speaker:better
Speaker:cooperation and
Speaker:less competition
Speaker:happening.
Speaker:And the stronger
Speaker:that we can
Speaker:create
Speaker:cooperation, the
Speaker:more likely that
Speaker:we can do away
Speaker:with states such
Speaker:as
Speaker:neurodiversity,
Speaker:or at least
Speaker:reduce the degree
Speaker:in the percentile
Speaker:of those who are
Speaker:neurodivergent in
Speaker:the populace,
Speaker:which is, I mean,
Speaker:just that, that
Speaker:label alone, that
Speaker:category needs so
Speaker:much new
Speaker:care, right?
Speaker:Because the
Speaker:levels of autism
Speaker:have rise, the
Speaker:level of
Speaker:depression
Speaker:has rise.
Speaker:You know, despite
Speaker:the fact that
Speaker:Western medical
Speaker:technologies have
Speaker:been approved
Speaker:upon, we're still
Speaker:having an influx
Speaker:of these
Speaker:particular
Speaker:states, which
Speaker:need not be if we
Speaker:can come together
Speaker:and unify our
Speaker:skill sets within
Speaker:a paradigm that's
Speaker:truly holistic.
Speaker:That's holistic.
Speaker:You know, there's
Speaker:that word thrown
Speaker:around, way too
Speaker:easily has been
Speaker:thrown around for
Speaker:decades, but what
Speaker:does it
Speaker:really mean?
Speaker:You know, and
Speaker:what I believe
Speaker:means is simply
Speaker:the embodiment of
Speaker:cooperation
Speaker:throughout
Speaker:different
Speaker:disciplines.
Speaker:That's holistic.
Speaker:It's not one
Speaker:discipline,
Speaker:during many
Speaker:different things
Speaker:in the body, is
Speaker:many disciplines
Speaker:supporting the
Speaker:complexity
Speaker:of the body.
Speaker:So that's where I
Speaker:came, and that's
Speaker:where the
Speaker:business is here.
Speaker:(Laughing) That's
Speaker:incredible.
Speaker:And I think
Speaker:you've already
Speaker:answered most of
Speaker:my follow-ups.
Speaker:What I really
Speaker:want to sort of
Speaker:just jump back at
Speaker:you on is just
Speaker:sort of your
Speaker:thoughts on the
Speaker:education model,
Speaker:because when it
Speaker:comes to sort of
Speaker:traditional
Speaker:medicine, and I'm
Speaker:definitely not
Speaker:qualified or also
Speaker:smart enough to
Speaker:make a judgment
Speaker:call on the way
Speaker:medicines talk,
Speaker:but I have a
Speaker:feeling you are,
Speaker:or at least you
Speaker:have some
Speaker:insights
Speaker:into the system.
Speaker:And the way I
Speaker:view it is
Speaker:exactly the way
Speaker:you view it, to
Speaker:an extent.
Speaker:I think that
Speaker:physicians have
Speaker:the best
Speaker:intentions at
Speaker:heart, but they
Speaker:put into this
Speaker:mold, they put
Speaker:this state of
Speaker:having to
Speaker:function based on
Speaker:a set of
Speaker:guidelines and a
Speaker:set of
Speaker:principles, and
Speaker:that's
Speaker:very myopic.
Speaker:And it causes
Speaker:this very sort of
Speaker:siloed approach
Speaker:to healthcare,
Speaker:which just
Speaker:doesn't work.
Speaker:And I've said
Speaker:this before on
Speaker:the podcast, I'm
Speaker:sure you've said
Speaker:it before on
Speaker:others, but I do
Speaker:think it
Speaker:needs to change.
Speaker:If you were, this
Speaker:is a bit of a hot
Speaker:take, but if you
Speaker:were sort of
Speaker:given carte
Speaker:blanche as to how
Speaker:you would
Speaker:potentially
Speaker:re-engineer the
Speaker:way medicines
Speaker:talk, what would
Speaker:you put more an
Speaker:emphasis on,
Speaker:excuse me?
Speaker:What would you
Speaker:sort of take an
Speaker:emphasis off?
Speaker:How would you
Speaker:sort of, briefly,
Speaker:because I mean,
Speaker:this could take
Speaker:us down to a
Speaker:whole other
Speaker:rabbit hole, but
Speaker:how would you
Speaker:sort of recreate
Speaker:medicine to
Speaker:become from a
Speaker:model standpoint,
Speaker:to be more
Speaker:effective and to
Speaker:help more people?
Speaker:Move away from a
Speaker:predominant
Speaker:statistical
Speaker:machine at the
Speaker:ideology.
Speaker:Evidence-based
Speaker:medicine, now
Speaker:we're talking
Speaker:about
Speaker:conventional
Speaker:Western medicine.
Speaker:We're not talking
Speaker:about alternative
Speaker:medicine, such as
Speaker:Chinese medicine
Speaker:and naturopathy
Speaker:or homeopathy,
Speaker:but we're talking
Speaker:about Western
Speaker:medicine, and it
Speaker:really started
Speaker:off really well.
Speaker:And being the
Speaker:known illusion,
Speaker:pharmacology is
Speaker:not the demon.
Speaker:It's just a
Speaker:prayer of use,
Speaker:that's the
Speaker:problem.
Speaker:As an example, if
Speaker:you wanted the
Speaker:word to be given
Speaker:in excess of
Speaker:belladonna,
Speaker:that's also not
Speaker:gonna be to any
Speaker:benefit of
Speaker:continuity
Speaker:of health.
Speaker:So it really is
Speaker:like you can't
Speaker:shout, "Oh, it's
Speaker:a big farmer that
Speaker:wants to
Speaker:kill us all."
Speaker:Well, no, a big
Speaker:farmer is only a
Speaker:cooperation,
Speaker:okay?
Speaker:A cooperation, a
Speaker:cooperation.
Speaker:It's a
Speaker:cooperation.
Speaker:And in being a
Speaker:cooperation, it
Speaker:has its profit
Speaker:margins that it
Speaker:needs to attain,
Speaker:like any other
Speaker:business.
Speaker:But it's not,
Speaker:it's like saying
Speaker:BMW is to blame
Speaker:for the road
Speaker:accidents,
Speaker:right?
Speaker:All the deaths on
Speaker:the road.
Speaker:No, no, and you
Speaker:can say, well,
Speaker:you know, they
Speaker:market their
Speaker:drugs and they
Speaker:try to get, they
Speaker:push the
Speaker:likelihood of
Speaker:sale onto doctors
Speaker:and so on.
Speaker:But what else are
Speaker:they meant to do?
Speaker:If they didn't do
Speaker:that, those
Speaker:medicines
Speaker:wouldn't also
Speaker:reach people that
Speaker:actually
Speaker:do need it.
Speaker:And this is where
Speaker:the discernment
Speaker:and improvement
Speaker:of the sermon is
Speaker:required with the
Speaker:end health
Speaker:practitioner,
Speaker:meaning the
Speaker:doctor, the
Speaker:GP, right?
Speaker:Everybody goes
Speaker:and sees.
Speaker:But the way in
Speaker:which,
Speaker:particularly when
Speaker:it comes to like
Speaker:socialistic
Speaker:countries like
Speaker:England or like
Speaker:France, where the
Speaker:healthcare is
Speaker:free, right?
Speaker:It's very much a
Speaker:conveyor
Speaker:belt system.
Speaker:I have a friend
Speaker:of mine who's a
Speaker:doctor based in
Speaker:Germany and
Speaker:before he went
Speaker:into private
Speaker:practice, he said
Speaker:that he had to
Speaker:see 2,000 people
Speaker:a month in order
Speaker:to make, I think
Speaker:it was like 8,000
Speaker:euro a month.
Speaker:2,000 people to
Speaker:make 8,000
Speaker:euro a month.
Speaker:So it's like 10,
Speaker:15 minutes, five
Speaker:sometimes minute
Speaker:consultations and
Speaker:it's just in and
Speaker:out, in and out.
Speaker:So what are you
Speaker:gonna do?
Speaker:Like, I can't do
Speaker:anything in 10
Speaker:minutes.
Speaker:Like I can have a
Speaker:conversation with
Speaker:somebody, but,
Speaker:and if I look at
Speaker:a lab report, I'm
Speaker:probably gonna
Speaker:look at like, you
Speaker:know, single
Speaker:markers and see
Speaker:if there's
Speaker:anything that
Speaker:really
Speaker:stands out.
Speaker:I'm not gonna
Speaker:have time to look
Speaker:at correlation or
Speaker:create a
Speaker:correlation
Speaker:analysis
Speaker:by it all.
Speaker:No way, because
Speaker:there's no time.
Speaker:And that design
Speaker:at least, there
Speaker:isn't any time.
Speaker:So I think the
Speaker:way in which to
Speaker:nonetheless
Speaker:support
Speaker:organizational
Speaker:construct in
Speaker:terms of
Speaker:financial
Speaker:resources,
Speaker:because we also
Speaker:have to think
Speaker:here, it's not
Speaker:just about giving
Speaker:everybody the
Speaker:equal opportunity
Speaker:of health.
Speaker:That's a great, I
Speaker:mean, that's a
Speaker:wonderful,
Speaker:wonderful
Speaker:sentiment and
Speaker:idea, but the
Speaker:reality is in
Speaker:order to do that,
Speaker:we also have to
Speaker:consider the
Speaker:economics
Speaker:of it all.
Speaker:Okay, and the
Speaker:economics of it
Speaker:all mean that we
Speaker:need to create
Speaker:organizational
Speaker:structures that
Speaker:can provide a
Speaker:personalized
Speaker:service to some
Speaker:degree, to a
Speaker:greater degree
Speaker:than is what
Speaker:currently given,
Speaker:but at the same
Speaker:time, not
Speaker:overburden the
Speaker:financial
Speaker:constraints of
Speaker:these
Speaker:organizations
Speaker:that have been
Speaker:set up by
Speaker:different
Speaker:governmental
Speaker:organizations
Speaker:across the world.
Speaker:And I think the
Speaker:way in which you
Speaker:can do this is
Speaker:by, biohacking is
Speaker:most certainly,
Speaker:it's not the
Speaker:foolproof
Speaker:structure, but it
Speaker:definitely has
Speaker:increased
Speaker:consciousness
Speaker:around wellness
Speaker:for many
Speaker:a people.
Speaker:And one can also
Speaker:argue that there
Speaker:are gonna be
Speaker:goods and bads to
Speaker:everything, okay?
Speaker:But however, if
Speaker:we just take the
Speaker:average, what
Speaker:happens when the
Speaker:person involved,
Speaker:it gets involved
Speaker:in a greater
Speaker:state of
Speaker:awareness of
Speaker:what's going on
Speaker:within
Speaker:themselves, they
Speaker:start to read
Speaker:articles.
Speaker:They start to
Speaker:watch
Speaker:YouTube videos.
Speaker:They start to
Speaker:engage with what
Speaker:it is that's
Speaker:actually going on
Speaker:within
Speaker:themselves.
Speaker:Now, if we can
Speaker:somewhat merge
Speaker:that community
Speaker:element, such as
Speaker:what's happening
Speaker:in biohacking
Speaker:into a greater
Speaker:community,
Speaker:thereby not
Speaker:creating the
Speaker:necessity of
Speaker:tribal mentality,
Speaker:but doing away
Speaker:with that tribal
Speaker:mentality, but
Speaker:still keeping the
Speaker:underlying
Speaker:positive premise
Speaker:of it all, then
Speaker:you can have one
Speaker:doctor, for
Speaker:example,
Speaker:that has,
Speaker:you know, somehow
Speaker:a doctor manages
Speaker:a particular
Speaker:county in
Speaker:England,
Speaker:or say a
Speaker:particular
Speaker:village, not a
Speaker:county, but a
Speaker:particular
Speaker:village in
Speaker:England.
Speaker:That doctor in
Speaker:the current
Speaker:construct of how
Speaker:the NHS is set
Speaker:up, patient eats
Speaker:a book, comes and
Speaker:sees a doctor on
Speaker:a one-to-one.
Speaker:But a one-to-one
Speaker:is 10
Speaker:minutes long.
Speaker:But it doesn't,
Speaker:you can't get
Speaker:anywhere
Speaker:with that.
Speaker:So what about,
Speaker:instead of having
Speaker:this design,
Speaker:you're having
Speaker:single
Speaker:consultation, you
Speaker:have a group
Speaker:model whereby the
Speaker:doctor becomes
Speaker:more proactively
Speaker:involved in the
Speaker:ongoing health of
Speaker:the community,
Speaker:right?
Speaker:It sets certain
Speaker:objectives, sets
Speaker:certain
Speaker:incentives for
Speaker:the community to
Speaker:elevate their
Speaker:health together.
Speaker:The biggest issue
Speaker:that I see in
Speaker:modern-day
Speaker:psychological
Speaker:health, at least,
Speaker:is the separation
Speaker:from man, from
Speaker:man's self, is
Speaker:isolation.
Speaker:We live in a
Speaker:world that's more
Speaker:populated now
Speaker:than ever before,
Speaker:yet we are more
Speaker:lonely than
Speaker:ever before.
Speaker:And that, just by
Speaker:that on its own,
Speaker:births many, many
Speaker:a disease.
Speaker:Okay, we're
Speaker:beings, we're a
Speaker:species that
Speaker:needs embrace.
Speaker:Okay, we're not
Speaker:learned
Speaker:creatures.
Speaker:No matter what
Speaker:anybody says,
Speaker:this warrior
Speaker:mentality, and go
Speaker:sit on top of a
Speaker:mountain and
Speaker:meditate for
Speaker:weeks or months
Speaker:or years on end,
Speaker:there may be,
Speaker:there are a few
Speaker:that have done
Speaker:it, they can do
Speaker:it, but whether
Speaker:or not it's
Speaker:healthy for a
Speaker:person or not,
Speaker:that's up
Speaker:for debate.
Speaker:And I don't
Speaker:think,
Speaker:personally, and
Speaker:again, I'm not
Speaker:omnipotent or
Speaker:omnipresent
Speaker:whatsoever, thank
Speaker:God for that,
Speaker:excuse the irony,
Speaker:of what I just
Speaker:said, but I do
Speaker:believe that
Speaker:humanity needs
Speaker:more compassion,
Speaker:and the only way
Speaker:in which we can
Speaker:improve upon the
Speaker:medical system is
Speaker:by implementing
Speaker:consideration for
Speaker:others in a
Speaker:community
Speaker:construct, really
Speaker:bring the
Speaker:community back
Speaker:together.
Speaker:So when something
Speaker:happens, it's not
Speaker:left to the nth
Speaker:degree when
Speaker:somebody's
Speaker:completely
Speaker:derailed, and
Speaker:then they're
Speaker:trying to have a
Speaker:10 minute
Speaker:consultation with
Speaker:the doctor
Speaker:to fix that.
Speaker:Because this
Speaker:faces it, things
Speaker:don't just happen
Speaker:overnight, unless
Speaker:you catch like
Speaker:typhoid fever,
Speaker:by the way, most
Speaker:deaths actually
Speaker:occur from
Speaker:non-communicable
Speaker:diseases,
Speaker:non-communicable
Speaker:diseases.
Speaker:78%, I think it
Speaker:was in 86, I
Speaker:can't remember,
Speaker:but it's between
Speaker:78 or 86, that
Speaker:was the number
Speaker:that I last saw
Speaker:on the steps of
Speaker:global
Speaker:deaths, right?
Speaker:Non-communicable
Speaker:diseases is
Speaker:responsible for
Speaker:the majority of
Speaker:deaths worldwide.
Speaker:And by that you
Speaker:mean things like
Speaker:AOCVD, heart
Speaker:disease, cancer,
Speaker:et cetera.
Speaker:Yeah, any disease
Speaker:that's not caused
Speaker:directly by a
Speaker:pathogen assault.
Speaker:Yeah.
Speaker:So, methylene
Speaker:blue, recovering
Speaker:from COVID.
Speaker:Not to be used
Speaker:perpetually, but
Speaker:the use of sort
Speaker:of circumstances,
Speaker:we had a
Speaker:conversation
Speaker:about this in the
Speaker:second, as well.
Speaker:We didn't need--
Speaker:So things like
Speaker:this, like you
Speaker:know, certain
Speaker:remedies, like
Speaker:methylene blue,
Speaker:that can be
Speaker:destructive,
Speaker:it most certainly
Speaker:can cause harm if
Speaker:it's used in the
Speaker:wrong construct,
Speaker:right?
Speaker:But it most
Speaker:certainly can
Speaker:alleviate harm if
Speaker:it's used in the
Speaker:right construct.
Speaker:But how do people
Speaker:know this?
Speaker:Like, I mean,
Speaker:I've got degrees
Speaker:in
Speaker:biochemistry, right?
Speaker:I've got degrees
Speaker:in nutritional
Speaker:science, but not
Speaker:everybody has a
Speaker:degree in
Speaker:biochemistry and
Speaker:nutritional
Speaker:science, so now,
Speaker:you know, you've
Speaker:got the media
Speaker:mention about its
Speaker:potential
Speaker:benefit, and
Speaker:there are
Speaker:incredible
Speaker:benefits behind
Speaker:this molecule.
Speaker:It truly is a
Speaker:molecule.
Speaker:But we need more
Speaker:of a community
Speaker:for people to be
Speaker:able to use these
Speaker:remedies that
Speaker:don't require a
Speaker:script
Speaker:successfully,
Speaker:rather than use
Speaker:it and feel
Speaker:like crap.
Speaker:Feel worse often
Speaker:than they did
Speaker:prior to
Speaker:using it.
Speaker:And this requires
Speaker:more of a
Speaker:community aspect.
Speaker:And I think this
Speaker:is the only way
Speaker:in which we'll be
Speaker:able to change
Speaker:the trajectory of
Speaker:modern-day
Speaker:medicine.
Speaker:When it comes to
Speaker:like the
Speaker:educational
Speaker:component of it,
Speaker:which is another
Speaker:part of the
Speaker:question
Speaker:that you asked,
Speaker:I think medical
Speaker:school starts off
Speaker:very well, but it
Speaker:ends terribly.
Speaker:(Laughs)
Speaker:Sort of, yeah,
Speaker:you sort of have
Speaker:this sort of,
Speaker:this base of
Speaker:biochemistry or
Speaker:physiology, and
Speaker:then you slowly
Speaker:sort of become a
Speaker:trained
Speaker:pharmacologist
Speaker:where you start
Speaker:to associate any
Speaker:disease outcome
Speaker:with a drug, and
Speaker:that's
Speaker:where you stop.
Speaker:That seems to be
Speaker:my take on it to
Speaker:a large extent.
Speaker:Well, the shame
Speaker:in it all is that
Speaker:it's even worse
Speaker:so than that,
Speaker:because it'd be
Speaker:great if they had
Speaker:more, most GPs
Speaker:have six months
Speaker:to maybe a year,
Speaker:depending upon
Speaker:which school you
Speaker:go to, in
Speaker:exposure to
Speaker:pharmacological
Speaker:studies.
Speaker:Do you know this?
Speaker:It's six months
Speaker:to a year.
Speaker:No, I didn't.
Speaker:Maximum year.
Speaker:Maximum year.
Speaker:That's
Speaker:incredible.
Speaker:Which is crazy,
Speaker:because if you
Speaker:think about it, a
Speaker:pharmacist, most,
Speaker:unless you do,
Speaker:some pharmacists
Speaker:are able to write
Speaker:scripts, but you
Speaker:have to go
Speaker:through extensive
Speaker:post-grad
Speaker:certification
Speaker:processes, very
Speaker:few of
Speaker:them have it.
Speaker:Yet, all doctors
Speaker:are able to write
Speaker:a script that
Speaker:have less
Speaker:knowledge than
Speaker:the pharmacist
Speaker:does on what it
Speaker:is that they're
Speaker:prescribing.
Speaker:That's
Speaker:disconcerting to
Speaker:say the least.
Speaker:And again, it's
Speaker:not the fault of the
Speaker:physician, is it?
Speaker:No, it's not.
Speaker:Definitely not
Speaker:the fault of the
Speaker:physician.
Speaker:Yeah.
Speaker:That was just a
Speaker:perfect podcast
Speaker:in
Speaker:itself, Justin.
Speaker:And I sort of, I
Speaker:love the way you
Speaker:took that, the
Speaker:fact that we sort
Speaker:of really sort
Speaker:of, and I should
Speaker:probably send
Speaker:this to my father
Speaker:because he was
Speaker:involved in
Speaker:community
Speaker:development for
Speaker:years, but it's
Speaker:almost like we've
Speaker:got to sort of
Speaker:rethink the
Speaker:paradigm
Speaker:completely and
Speaker:sort of place
Speaker:more emphasis on
Speaker:the community.
Speaker:How you then go
Speaker:about educating
Speaker:the masses, for
Speaker:the want of
Speaker:better word, is
Speaker:probably another
Speaker:question best
Speaker:left to
Speaker:another day.
Speaker:But it does
Speaker:make sense,
Speaker:bringing the
Speaker:awareness of
Speaker:health to the
Speaker:individual, and
Speaker:almost from a
Speaker:preventative
Speaker:standpoint.
Speaker:So encouraging
Speaker:people to take,
Speaker:how do I
Speaker:put this?
Speaker:Encouraging
Speaker:people to take
Speaker:responsibility
Speaker:for their own
Speaker:health and
Speaker:creating
Speaker:messaging
Speaker:around that.
Speaker:And I think
Speaker:that's where the
Speaker:biohacking
Speaker:community is
Speaker:effective.
Speaker:I think it does
Speaker:get a bit lost in
Speaker:the weeds in
Speaker:terms of maybe
Speaker:focusing on the
Speaker:minutiae more
Speaker:often than the
Speaker:actual needle
Speaker:movers, which
Speaker:just aren't sexy
Speaker:at the end of the
Speaker:day, are they?
Speaker:Nobody wants to
Speaker:necessarily sort
Speaker:of go to bed when
Speaker:it gets dark and
Speaker:wake up when it
Speaker:gets light.
Speaker:They want to sort
Speaker:of play around
Speaker:with the red
Speaker:light and the
Speaker:$10,000 coin
Speaker:plunge or
Speaker:whatever it is.
Speaker:So how you get
Speaker:around that one?
Speaker:It is
Speaker:TVT.
Speaker:Well, I want to come back down to
Speaker:leadership
Speaker:authority, and we
Speaker:look into
Speaker:different social
Speaker:constructs and
Speaker:theories around
Speaker:that as well,
Speaker:which begs the
Speaker:question of like,
Speaker:how much
Speaker:authority are we
Speaker:as a collective
Speaker:giving those who
Speaker:have voices?
Speaker:And what are
Speaker:their intentions?
Speaker:Like, obviously
Speaker:we all need to
Speaker:make money in
Speaker:this lifetime.
Speaker:There's nothing
Speaker:wrong with making
Speaker:money, but I
Speaker:think it's really
Speaker:easy for me at
Speaker:least, and maybe
Speaker:this is a vouch
Speaker:of advice for
Speaker:anybody that may
Speaker:consider
Speaker:reviewing what it
Speaker:is that they're
Speaker:hearing.
Speaker:Any moment when
Speaker:an influencer of
Speaker:any split in the
Speaker:biohacking or policing
Speaker:especially comes
Speaker:with a polarized
Speaker:view, I stop
Speaker:listening
Speaker:to them.
Speaker:I stop listening
Speaker:to them.
Speaker:This is good for
Speaker:you, this is bad
Speaker:for you, blah,
Speaker:blah, blah, blah,
Speaker:blah, blah,
Speaker:blah, blah.
Speaker:Like, you know,
Speaker:again, like for
Speaker:example,
Speaker:palm oil, palm
Speaker:oil, okay, it's
Speaker:terrible, but it
Speaker:is terrible, but
Speaker:it also has
Speaker:certain potential
Speaker:applications
Speaker:outside of the
Speaker:food industry.
Speaker:Okay, so it's not
Speaker:all bad.
Speaker:Yes, there is
Speaker:obviously an
Speaker:impact that has
Speaker:on nature, but
Speaker:tell me what
Speaker:doesn't have an
Speaker:impact on nature
Speaker:given the
Speaker:technological
Speaker:construct of
Speaker:humanity.
Speaker:You know, so
Speaker:there are ways in
Speaker:which we need to
Speaker:mitigate that for
Speaker:sure, but
Speaker:nothing,
Speaker:everything needs
Speaker:to be considered
Speaker:in content and
Speaker:context and
Speaker:content.
Speaker:And a polarized
Speaker:view often comes
Speaker:with a bit of a
Speaker:buy-in or a sale
Speaker:for the person to
Speaker:buy into, okay.
Speaker:I'm not gonna
Speaker:name any names,
Speaker:but not too long
Speaker:ago, there was a
Speaker:very well-known
Speaker:influencer in the
Speaker:space who had
Speaker:everything to say
Speaker:about melatonin
Speaker:and how it can
Speaker:induce the
Speaker:likelihood of an
Speaker:increase of
Speaker:myocardial
Speaker:infarction.
Speaker:And he cited
Speaker:certain studies,
Speaker:but anybody that
Speaker:doesn't know how
Speaker:to read studies
Speaker:will just take
Speaker:what he said for
Speaker:face value, but
Speaker:anybody that does
Speaker:know how to read
Speaker:a study will
Speaker:actually look
Speaker:into the
Speaker:demographic of
Speaker:which was
Speaker:utilized for the
Speaker:study and realize
Speaker:that a lot of
Speaker:these people
Speaker:actually had
Speaker:pre-existing
Speaker:heart conditions
Speaker:in the
Speaker:first place.
Speaker:These are not
Speaker:healthy
Speaker:individuals.
Speaker:Yeah, no, it's
Speaker:just so
Speaker:context-dependent
Speaker:at the end of the
Speaker:day, isn't it?
Speaker:And I love the
Speaker:nutrition and
Speaker:energy too.
Speaker:It's ultimately
Speaker:comes back to
Speaker:sort of finding
Speaker:that middle
Speaker:ground, because
Speaker:ultimately I feel
Speaker:that we're all on
Speaker:the bell curve
Speaker:and obviously
Speaker:you're going to
Speaker:have extreme
Speaker:outliers at
Speaker:either end,
Speaker:people who are
Speaker:going to thrive
Speaker:just caring for
Speaker:this energy on a
Speaker:carnival diet and
Speaker:people who are
Speaker:gonna thrive
Speaker:maybe on a vegan
Speaker:diet on the
Speaker:other end.
Speaker:But yeah, I think
Speaker:ultimately we do
Speaker:all sort of fall
Speaker:somewhere in the
Speaker:middle, don't we?
Speaker:And it's
Speaker:interesting to
Speaker:see many of the
Speaker:influences in
Speaker:this space.
Speaker:You're Paul
Speaker:Saladinas of the
Speaker:world, for
Speaker:example, who sort
Speaker:of started out
Speaker:and maybe, I'm
Speaker:not sure how many
Speaker:people are aware
Speaker:of this, but he
Speaker:started out
Speaker:vegan, then he
Speaker:went fully
Speaker:carnival.
Speaker:And then he sort
Speaker:of ended up
Speaker:essentially an
Speaker:omnivore in
Speaker:the middle.
Speaker:So I do think it
Speaker:speaks to your
Speaker:point in that
Speaker:respect.
Speaker:Anyway,
Speaker:Justin, I think
Speaker:we've already
Speaker:been going for 14
Speaker:minutes and
Speaker:technically we
Speaker:haven't even
Speaker:started his
Speaker:conversation.
Speaker:So taking all
Speaker:that into
Speaker:account, and that
Speaker:was truly the
Speaker:most interesting
Speaker:introduction to
Speaker:Paul Saladinas,
Speaker:so thank you.
Speaker:Let's dive into
Speaker:this concept of
Speaker:immunometabolism.
Speaker:Now, I think when
Speaker:going into a
Speaker:topic as complex,
Speaker:potentially as
Speaker:complex as this,
Speaker:it's great to
Speaker:have a baseline
Speaker:and understanding
Speaker:of the basic
Speaker:physiology, the
Speaker:basic
Speaker:biochemistry.
Speaker:So to start off
Speaker:with, would you
Speaker:mind breaking
Speaker:down for the
Speaker:listeners what
Speaker:the immune system
Speaker:fundamentally is?
Speaker:And then we could
Speaker:maybe branch into
Speaker:more discussion
Speaker:about how that
Speaker:relates to
Speaker:metabolism.
Speaker:But yeah,
Speaker:immunology 101,
Speaker:as it were, would
Speaker:you mind just
Speaker:sort of providing
Speaker:us with a
Speaker:breakdown of the
Speaker:concepts there?
Speaker:It's an
Speaker:environmental
Speaker:foreman.
Speaker:Let me explain.
Speaker:So I was like,
Speaker:what do you mean
Speaker:environment
Speaker:foreman?
Speaker:It pretty much
Speaker:directs what
Speaker:needs to happen
Speaker:between two
Speaker:different
Speaker:environment, well
Speaker:within an
Speaker:environment based
Speaker:upon two
Speaker:different
Speaker:environments.
Speaker:We live in an
Speaker:environment, like
Speaker:there is a
Speaker:microcosm to the
Speaker:macrocosm.
Speaker:So we live in the
Speaker:world, and the
Speaker:world is a part
Speaker:of the solar
Speaker:system, and the
Speaker:solar system is
Speaker:part of the
Speaker:galaxy, and the
Speaker:galaxy is part of
Speaker:the universe, and
Speaker:there are
Speaker:probably multiple
Speaker:universes.
Speaker:Maybe, maybe not.
Speaker:I don't know, I'm
Speaker:not a quantum
Speaker:physicist, but I
Speaker:would assume that
Speaker:they are.
Speaker:So within we take
Speaker:the macro to the
Speaker:macrocosm,
Speaker:everything has
Speaker:the potential of
Speaker:symbiosis, or
Speaker:conflict to that
Speaker:symbiosis.
Speaker:Now when conflict
Speaker:exists to that
Speaker:symbiosis, we
Speaker:have to consider
Speaker:what is it
Speaker:between the two
Speaker:environments
Speaker:that's acting in
Speaker:opposition to one
Speaker:another.
Speaker:And this is where
Speaker:the immune system
Speaker:comes in, because
Speaker:it tries to sort
Speaker:out the
Speaker:oppositional
Speaker:activities
Speaker:between our
Speaker:internal
Speaker:environment as to
Speaker:what's happening
Speaker:outside of
Speaker:ourselves.
Speaker:So in the immune
Speaker:system, the
Speaker:immune system
Speaker:itself, from a
Speaker:scientific
Speaker:perspective, you
Speaker:have two major
Speaker:components.
Speaker:You have the
Speaker:adaptive and the
Speaker:innate
Speaker:immune system.
Speaker:The innate immune
Speaker:system has been
Speaker:around for a
Speaker:lot longer.
Speaker:The adaptive
Speaker:immune system
Speaker:came about
Speaker:subsequently
Speaker:thereafter.
Speaker:The innate immune
Speaker:system comprises
Speaker:elements such as
Speaker:macrophage, such
Speaker:as neutrophils,
Speaker:such as natural
Speaker:killer cells and
Speaker:granular
Speaker:cytoplasmophils
Speaker:and basophils.
Speaker:They have less
Speaker:specificity in
Speaker:order to address
Speaker:whatever burden
Speaker:might be plaguing
Speaker:the body, but
Speaker:they have more
Speaker:immediate
Speaker:reactions.
Speaker:And then in their
Speaker:immediate
Speaker:reaction,
Speaker:particularly
Speaker:dendritic cells,
Speaker:they create what
Speaker:they call
Speaker:presentation.
Speaker:They they
Speaker:optimize.
Speaker:Basically they
Speaker:decorate what,
Speaker:like for example,
Speaker:a pathogen,
Speaker:enabling the
Speaker:adaptive immune
Speaker:players, which
Speaker:are your B and
Speaker:your T
Speaker:lymphocytes, to
Speaker:come in and say,
Speaker:okay, cool, these
Speaker:guys
Speaker:shouldn't be here.
Speaker:And the B and the
Speaker:T lymphocytes are
Speaker:initially your
Speaker:artillery,
Speaker:because when we
Speaker:get into the
Speaker:solid danger
Speaker:response part of
Speaker:the discussion,
Speaker:I'll explain it a
Speaker:little bit more,
Speaker:initially you
Speaker:proliferate
Speaker:T cells.
Speaker:So the innate
Speaker:immune system
Speaker:will launch of
Speaker:its defense.
Speaker:And in doing so,
Speaker:create APC and
Speaker:then in that, the
Speaker:body will create
Speaker:a reaction in
Speaker:releasing a lot
Speaker:of naive or
Speaker:increasing the
Speaker:production of
Speaker:your
Speaker:naive T cells.
Speaker:Then over time,
Speaker:with the APC is
Speaker:coming into
Speaker:contact with
Speaker:these particular
Speaker:lymph node
Speaker:points, then the
Speaker:specific type of
Speaker:T cells will
Speaker:proliferate.
Speaker:You have two
Speaker:subsets in my T
Speaker:helper cells, T
Speaker:regulatory cells,
Speaker:and then
Speaker:cytotoxic
Speaker:lymphocytes.
Speaker:And then you also
Speaker:have your
Speaker:antibodies, the
Speaker:cell that's
Speaker:within your B
Speaker:cell complexes,
Speaker:your IgMs, your
Speaker:IgGs, IgAs
Speaker:and IgEs.
Speaker:Depending upon
Speaker:what it is,
Speaker:that's within
Speaker:those particular
Speaker:antibodies and
Speaker:that those
Speaker:particular T cell
Speaker:responses will
Speaker:come into
Speaker:the mix.
Speaker:Now it's very
Speaker:important that a
Speaker:response is
Speaker:calibrated to a
Speaker:point where it
Speaker:doesn't cause
Speaker:self-autoreactivity
Speaker:in the body.
Speaker:Otherwise you
Speaker:have a state of
Speaker:perpetual assault
Speaker:that the immune
Speaker:system perceives
Speaker:that it is
Speaker:required to
Speaker:facilitate, even
Speaker:though there
Speaker:isn't a
Speaker:continual threat.
Speaker:Or there is no
Speaker:longer the degree
Speaker:of threat that it
Speaker:perceives that it
Speaker:actually has.
Speaker:So it's very much
Speaker:a concert.
Speaker:And it's very
Speaker:much like a
Speaker:football game,
Speaker:whereby the ball
Speaker:is passed into
Speaker:specific players
Speaker:depending upon
Speaker:the certain
Speaker:sequence of how
Speaker:the game is
Speaker:playing out.
Speaker:So those are your
Speaker:two major
Speaker:components that
Speaker:you've been
Speaker:using, the innate
Speaker:and the adaptive
Speaker:and obviously the
Speaker:players.
Speaker:What's very
Speaker:interesting in
Speaker:the innate immune
Speaker:system is that
Speaker:the stem cells
Speaker:that produce most
Speaker:of the innate
Speaker:immune players
Speaker:are lymphoid
Speaker:stem cells.
Speaker:Sorry, I'm sorry,
Speaker:myeloid
Speaker:stem cells.
Speaker:Whereas the stem
Speaker:cells that
Speaker:produce most of
Speaker:the adaptive
Speaker:immune players
Speaker:are lymphoid,
Speaker:except albeit for
Speaker:or natural
Speaker:killer cells.
Speaker:And this is
Speaker:highly relevant
Speaker:because your
Speaker:natural killer
Speaker:cells have the
Speaker:greatest degree
Speaker:of specificity in
Speaker:contrast to the
Speaker:other innate
Speaker:immune players in
Speaker:being able to
Speaker:detect faulty
Speaker:mutations.
Speaker:So when you have
Speaker:a lower natural
Speaker:killer cells,
Speaker:your risk of
Speaker:cancer increases,
Speaker:your body's
Speaker:ability to resist
Speaker:things like
Speaker:perpetual cell
Speaker:wall deficient
Speaker:attacks such as
Speaker:Lyme disease
Speaker:reduces, your
Speaker:body's ability to
Speaker:mitigate
Speaker:expression of
Speaker:chronic envelope
Speaker:based viruses
Speaker:like
Speaker:Epstein-Bach,
Speaker:cyclo-mekovirus
Speaker:decreases.
Speaker:So when you have
Speaker:lower natural
Speaker:killer cells, you
Speaker:become
Speaker:vulnerable.
Speaker:And what happens
Speaker:is when you
Speaker:become
Speaker:vulnerable, the
Speaker:other innate
Speaker:players try to
Speaker:step in because
Speaker:there's a
Speaker:deficiency of one
Speaker:of their
Speaker:teammates.
Speaker:They try to come
Speaker:in and help where
Speaker:their teammates
Speaker:not able to take
Speaker:on the workload.
Speaker:But in them doing
Speaker:that, because of
Speaker:their degree of
Speaker:specificity isn't
Speaker:as targeted as to
Speaker:what natural
Speaker:killer cells, and
Speaker:it's also by way
Speaker:of the stem cells
Speaker:that they
Speaker:originate from as
Speaker:to why, this
Speaker:creates a
Speaker:likelihood of
Speaker:perpetual,
Speaker:chronic,
Speaker:low-grade
Speaker:inflammation.
Speaker:Now, this
Speaker:low-grade
Speaker:inflammation can
Speaker:also further
Speaker:exhaust the
Speaker:adaptive immune
Speaker:system over time.
Speaker:And HIV is a
Speaker:classical
Speaker:example.
Speaker:You know, it's an
Speaker:extreme example,
Speaker:but it's a
Speaker:classical example
Speaker:of this whereby
Speaker:HIV hijacks
Speaker:certain
Speaker:CD4 cells.
Speaker:The CD4 cells
Speaker:present
Speaker:themselves along
Speaker:the lymph nodes.
Speaker:The innate immune
Speaker:system launches
Speaker:in a fence, but
Speaker:meanwhile it's
Speaker:launching in the
Speaker:fence in the
Speaker:wrong areas,
Speaker:thereby reducing
Speaker:the adaptive
Speaker:capacity to
Speaker:launch a
Speaker:cytotoxic
Speaker:lymphocyte
Speaker:response at the
Speaker:point where the
Speaker:immune system
Speaker:exhausts itself
Speaker:and then you
Speaker:develop eight.
Speaker:Okay.
Speaker:Would this be a,
Speaker:excuse me, would
Speaker:this be a point
Speaker:where something
Speaker:like a cytokine
Speaker:resistance of
Speaker:sorts would
Speaker:develop,
Speaker:potentially where
Speaker:you've got an
Speaker:anti-inflammatory
Speaker:cytokin coming
Speaker:into the mix, or
Speaker:am I a bit off
Speaker:base there?
Speaker:I'm just trying
Speaker:to piece this
Speaker:together as you
Speaker:go with regards
Speaker:to the natural
Speaker:killer cells.
Speaker:Cytokin
Speaker:resistance,
Speaker:you're talking
Speaker:about like
Speaker:interleukin-10 as
Speaker:a predominant
Speaker:anti-cytokin.
Speaker:Yes and no, and it's contextual,
Speaker:because it
Speaker:depends upon the
Speaker:quantitative
Speaker:release of other
Speaker:cytokines in
Speaker:ratio to that
Speaker:interleukin-10
Speaker:response.
Speaker:As an example, if
Speaker:you have a lot of
Speaker:interleukin-4
Speaker:being expressed
Speaker:at the same time
Speaker:as
Speaker:interleukin-10,
Speaker:and subsequently
Speaker:you also might
Speaker:have an
Speaker:interleukin-13
Speaker:activity
Speaker:happening in
Speaker:conjunction with
Speaker:interleukin-4,
Speaker:this may
Speaker:propagate a
Speaker:neutrophilic
Speaker:response.
Speaker:And the
Speaker:neutrophilic
Speaker:response can
Speaker:increase the,
Speaker:exacerbate a
Speaker:release of
Speaker:hydrogen
Speaker:peroxide, which
Speaker:is what they do.
Speaker:That's where
Speaker:hydrogen peroxide
Speaker:is actually part
Speaker:of the
Speaker:immune system.
Speaker:Immune system
Speaker:actually release
Speaker:hydrogen peroxide
Speaker:as a form of very
Speaker:strong
Speaker:anti-microbial.
Speaker:This is why, like
Speaker:if you've had
Speaker:hydrogen peroxide
Speaker:IDs and so on,
Speaker:it's because it's
Speaker:supporting an
Speaker:exhausted immune
Speaker:system, this FYI.
Speaker:Interesting.
Speaker:Yeah, no, that's
Speaker:a tip that I do
Speaker:not know.
Speaker:So with this
Speaker:whole paradigm,
Speaker:it's not just
Speaker:about like, okay,
Speaker:interleukin-10 is
Speaker:there, we're
Speaker:still having
Speaker:information.
Speaker:Well, no, it's,
Speaker:it's looking at
Speaker:it as doing what
Speaker:it needs to do,
Speaker:but what else is
Speaker:going on in this
Speaker:whole paradigm?
Speaker:And this is where
Speaker:like measuring a
Speaker:cytokine map
Speaker:provides to be
Speaker:incredibly useful
Speaker:when you're
Speaker:seeing the
Speaker:complex activity
Speaker:of the entire
Speaker:immune system.
Speaker:You know, two
Speaker:tests that I
Speaker:always, not
Speaker:always, but that
Speaker:I enjoy running
Speaker:because I get so
Speaker:much insight from
Speaker:them,
Speaker:particularly in
Speaker:cases of chronic
Speaker:fatigue, not
Speaker:necessarily
Speaker:always long walk
Speaker:over, just
Speaker:chronic fatigue
Speaker:cases, because in
Speaker:my clinical
Speaker:experience, in
Speaker:supporting those
Speaker:with chronic
Speaker:fatigue, 90% of
Speaker:the time it has
Speaker:an association
Speaker:with a exhausted
Speaker:natural killer
Speaker:cell response and
Speaker:subsequently a
Speaker:perpetuated
Speaker:monocyte
Speaker:inflammatory
Speaker:response.
Speaker:So in these
Speaker:cases, they
Speaker:always, no matter
Speaker:how much iron or
Speaker:iron-rich foods
Speaker:they eat, they
Speaker:always have low
Speaker:serum iron.
Speaker:If this is you,
Speaker:and I'm speaking
Speaker:to the audience
Speaker:now, if you eat a
Speaker:lot of red meat,
Speaker:you're taking
Speaker:trimethylglycine
Speaker:to help with
Speaker:hyperchloridea in
Speaker:case you may have
Speaker:that and try to
Speaker:absorb
Speaker:iron better.
Speaker:And yet your
Speaker:serum iron
Speaker:concentration is
Speaker:always on the low
Speaker:side or maybe
Speaker:even deficient,
Speaker:despite the fact
Speaker:that you might be
Speaker:eating it's a
Speaker:kilogram of
Speaker:steak a day.
Speaker:Whether you are
Speaker:or you're not, if
Speaker:it is that you're
Speaker:full of this
Speaker:paradigm and yet
Speaker:no matter what
Speaker:you do, albeit
Speaker:from maybe direct
Speaker:super
Speaker:thermal iron,
Speaker:your iron levels
Speaker:are always
Speaker:suppressed.
Speaker:Consider the fact
Speaker:that your
Speaker:monocytes are
Speaker:microphage on a
Speaker:state of
Speaker:perpetual
Speaker:reactivation.
Speaker:Okay, they're in
Speaker:a state of M1,
Speaker:microphage,
Speaker:immunotype.
Speaker:And this is
Speaker:really elusive
Speaker:because like, if
Speaker:you just look
Speaker:into a white
Speaker:blood salt
Speaker:differential to
Speaker:try and determine
Speaker:whether or not
Speaker:this is
Speaker:happening,
Speaker:it doesn't always
Speaker:show itself on a
Speaker:standard white
Speaker:blood salt
Speaker:differential
Speaker:because unless
Speaker:you're gonna do
Speaker:immunological
Speaker:survey every day
Speaker:for a period of
Speaker:seven days, in
Speaker:these particular
Speaker:cases, you're not
Speaker:always
Speaker:necessarily gonna
Speaker:get the window
Speaker:within which the
Speaker:immune systems
Speaker:are compromised,
Speaker:showing the true
Speaker:effect of what
Speaker:isn't or what is
Speaker:actually
Speaker:going on.
Speaker:So this is where
Speaker:running a
Speaker:lymphocyte flow
Speaker:cytometry as well
Speaker:as a cytokine
Speaker:map, proves to be
Speaker:incredibly
Speaker:insightful
Speaker:because this
Speaker:gives more of the
Speaker:specificity in
Speaker:terms of like
Speaker:microphage
Speaker:inflammatory
Speaker:proteins and so
Speaker:on and other side
Speaker:of kinds of that
Speaker:nature that could
Speaker:be expressed in
Speaker:the background,
Speaker:actually
Speaker:impacting anemia,
Speaker:iron-based
Speaker:anemia.
Speaker:Again, despite
Speaker:the fact of any
Speaker:supplementation
Speaker:or nutritional
Speaker:augmentation,
Speaker:when one is
Speaker:experiencing
Speaker:perpetual
Speaker:iron-based
Speaker:anemia,
Speaker:especially in
Speaker:situations where
Speaker:they have
Speaker:supplements, that
Speaker:comes to consider
Speaker:that there is an
Speaker:immunological or
Speaker:an immunological
Speaker:distorted
Speaker:perception
Speaker:going on.
Speaker:And I think
Speaker:that's really
Speaker:important is
Speaker:that, yes, the
Speaker:immune system can
Speaker:exhaust itself,
Speaker:however, it's not
Speaker:always the point,
Speaker:it's like the
Speaker:whole concept
Speaker:behind adrenal
Speaker:exhaustion.
Speaker:Do the adrenal
Speaker:glands really
Speaker:exhaust
Speaker:themselves or is
Speaker:it the receptor
Speaker:makeup that
Speaker:actually starts
Speaker:to lose the
Speaker:sensitivity to
Speaker:the effect of the
Speaker:glucocorticoids?
Speaker:Or is it the fact
Speaker:that it redirects
Speaker:your other
Speaker:catecholamines or
Speaker:other hormone
Speaker:specifically to
Speaker:try and maintain
Speaker:the state of pH
Speaker:in the body?
Speaker:The organic
Speaker:gradient
Speaker:in the body.
Speaker:So again, the
Speaker:immune system is
Speaker:the same, is
Speaker:that, I guess, in
Speaker:most only you can
Speaker:get exhausted and
Speaker:certain
Speaker:components of the
Speaker:immune system can
Speaker:tire, but you
Speaker:have to ask
Speaker:yourself why?
Speaker:Why is the immune
Speaker:system exhausted
Speaker:in its cytotoxic
Speaker:effect, for
Speaker:example?
Speaker:And often the
Speaker:answer is because
Speaker:there's an
Speaker:imbalance between
Speaker:its innate and
Speaker:adaptive
Speaker:components.
Speaker:Yeah, that was
Speaker:truly, I could
Speaker:have used all of
Speaker:that when
Speaker:prepping for this
Speaker:episode, that
Speaker:would have made
Speaker:life a lot easier
Speaker:instead of trying
Speaker:to sort of figure
Speaker:out the
Speaker:immunology from
Speaker:scratch, which I
Speaker:will fully admit,
Speaker:I am not that
Speaker:proficient in.
Speaker:So I will for one
Speaker:will be relisting
Speaker:to all of that
Speaker:because
Speaker:truthfully I'm
Speaker:talking about 80%
Speaker:of it, some of it
Speaker:was beyond me,
Speaker:however, that was
Speaker:incredible,
Speaker:thank you.
Speaker:And the audience
Speaker:listening, you
Speaker:may be a bit
Speaker:flummoxed by
Speaker:that, but I think
Speaker:if you were to
Speaker:give it a second
Speaker:listen after
Speaker:having listened
Speaker:to the rest of
Speaker:the episode, of
Speaker:course, you will
Speaker:pick up on a lot
Speaker:of what Justin
Speaker:just said.
Speaker:And I know going
Speaker:forwards, that's
Speaker:going to really
Speaker:help the rest of
Speaker:the discussion
Speaker:that we're going
Speaker:to have about the
Speaker:sort of concept
Speaker:of
Speaker:immunomatabolism,
Speaker:which really is a
Speaker:perfect segue
Speaker:into that, into
Speaker:this concept of
Speaker:immunomatabolism.
Speaker:And the way I
Speaker:understand it,
Speaker:sort of at a very
Speaker:layman's
Speaker:level is that
Speaker:the immune system
Speaker:obviously at
Speaker:higher levels,
Speaker:what controls the
Speaker:inflammatory
Speaker:response
Speaker:in the body.
Speaker:And when that
Speaker:inflammatory
Speaker:response is out
Speaker:of control, then
Speaker:there's a strong
Speaker:carry over to
Speaker:what is
Speaker:colloquially
Speaker:known as
Speaker:metabolism.
Speaker:That being the
Speaker:result or the
Speaker:collection of
Speaker:various organ
Speaker:systems
Speaker:throughout the
Speaker:body, everything
Speaker:from thyroid to
Speaker:pancreatic and
Speaker:insulin function,
Speaker:et cetera.
Speaker:And I'd love to
Speaker:sort of chat
Speaker:about those
Speaker:upstream
Speaker:triggers points
Speaker:in a bit.
Speaker:But to start off
Speaker:with, would you
Speaker:sort of mind
Speaker:breaking down the
Speaker:way you see
Speaker:immunomatabolism?
Speaker:Because I think
Speaker:I've got the gist
Speaker:of it, but not
Speaker:entirely.
Speaker:So would you
Speaker:provide the
Speaker:audience with a
Speaker:breakdown of this
Speaker:term and then we
Speaker:can discuss it in
Speaker:a bit more depth
Speaker:from there.
Speaker:Well, I've got to
Speaker:give credit to
Speaker:Professor
Speaker:Robert Naviou.
Speaker:You know, that's
Speaker:the cornerstone
Speaker:of my
Speaker:understanding
Speaker:behind this
Speaker:concept.
Speaker:There are others
Speaker:that definitely
Speaker:contributed
Speaker:toward it.
Speaker:But by far he's
Speaker:being the most
Speaker:influential in
Speaker:alluding to my
Speaker:understanding as
Speaker:to what this
Speaker:paradigm actually
Speaker:entails.
Speaker:I mentioned
Speaker:Albert Zangorgi
Speaker:before when I was
Speaker:talking about
Speaker:methylene blue.
Speaker:He also went into
Speaker:this prior
Speaker:to Naviou.
Speaker:And prior to that
Speaker:generation was
Speaker:John Beard back
Speaker:in the early part
Speaker:of the 1900s, who
Speaker:was the first to
Speaker:treat cancer by
Speaker:injecting
Speaker:digestive enzymes
Speaker:into tumors.
Speaker:So this whole
Speaker:paradigm is
Speaker:actually started
Speaker:by looking at
Speaker:cancer as a
Speaker:physiological
Speaker:process, right?
Speaker:And then
Speaker:determining what
Speaker:was going on
Speaker:within cancer.
Speaker:But then
Speaker:obviously then as
Speaker:time went on, it
Speaker:actually was made
Speaker:apparent
Speaker:that the rate of
Speaker:respiratory chain
Speaker:activity has a
Speaker:dramatic impact
Speaker:over the
Speaker:availability of
Speaker:ATP, but not only
Speaker:the availability
Speaker:of ATP, it's
Speaker:potential
Speaker:oxidative
Speaker:byproducts.
Speaker:So mitochondria
Speaker:produce a lot of
Speaker:oxidants because
Speaker:they produce a
Speaker:lot of energy,
Speaker:which means that
Speaker:their membranes
Speaker:are highly
Speaker:susceptible to
Speaker:oxidative stress
Speaker:if they're not
Speaker:maintained in a
Speaker:neutral anhydrous
Speaker:state, okay?
Speaker:Like a battery.
Speaker:You have to think
Speaker:of your
Speaker:mitochondria like
Speaker:a battery.
Speaker:If the polarity
Speaker:or the ion
Speaker:exchange is not
Speaker:in well balanced
Speaker:within
Speaker:mitochondria,
Speaker:that battery gets
Speaker:hot, okay?
Speaker:And what can
Speaker:induce this if we
Speaker:do not, or if our
Speaker:mitochondria
Speaker:don't have the
Speaker:capacity to
Speaker:readily shift
Speaker:from different
Speaker:energy dynamics,
Speaker:meaning from
Speaker:something as
Speaker:immediate as the
Speaker:creatine
Speaker:phosphate system
Speaker:to the
Speaker:glycolysis, to
Speaker:triclobolic acid,
Speaker:to electron
Speaker:transport chain
Speaker:and shifting.
Speaker:Because the thing
Speaker:is you shouldn't
Speaker:just do one.
Speaker:Like there is a
Speaker:flow of them all
Speaker:happening
Speaker:simultaneously
Speaker:but to varying
Speaker:degrees.
Speaker:But when there's
Speaker:a requirement in
Speaker:the shift to take
Speaker:place into a more
Speaker:predominant state
Speaker:of respiratory
Speaker:chain activity,
Speaker:energy
Speaker:production, and
Speaker:that shift can't
Speaker:take place
Speaker:effectively, then
Speaker:what happens is
Speaker:these
Speaker:mitochondria
Speaker:become highly
Speaker:radical.
Speaker:So they start to
Speaker:not only damage
Speaker:their own DNA but
Speaker:they start to
Speaker:damage DNA within
Speaker:proximity from
Speaker:expression from
Speaker:the nucleus of
Speaker:the cell.
Speaker:And this is where
Speaker:over time you can
Speaker:start to have
Speaker:mutations occur
Speaker:as well.
Speaker:Albeit that even
Speaker:prior to these
Speaker:mutations
Speaker:occurring an
Speaker:increase in the
Speaker:likelihood of a
Speaker:concept called
Speaker:immunological
Speaker:citizens may take
Speaker:place as well.
Speaker:So metabolism,
Speaker:immunology, what
Speaker:was the term?
Speaker:How did you
Speaker:connect
Speaker:those two terms?
Speaker:The idea of sort
Speaker:of
Speaker:immunomatabolism.
Speaker:Immunomatabolism
Speaker:of our, see the
Speaker:moments of the
Speaker:light
Speaker:dislikes here.
Speaker:Immunomatabolism
Speaker:really is, as you
Speaker:mentioned, the
Speaker:segue between how
Speaker:the internal
Speaker:environment of
Speaker:our physiology is
Speaker:responding to
Speaker:stimuli from our
Speaker:external
Speaker:environment.
Speaker:And subsequently
Speaker:within that
Speaker:response, how
Speaker:well we are
Speaker:managing the
Speaker:production as
Speaker:well as recycling
Speaker:of energy.
Speaker:So going back to
Speaker:Professor
Speaker:Navia's work,
Speaker:there he created
Speaker:a concept called
Speaker:the cell danger
Speaker:response state,
Speaker:which involves
Speaker:different states
Speaker:of respiratory
Speaker:chain activity in
Speaker:the mitochondria,
Speaker:going from a
Speaker:neutral, or I'm
Speaker:gonna say a
Speaker:neutral state, a
Speaker:energetically
Speaker:efficient state.
Speaker:So think of your
Speaker:mitochondria when
Speaker:they're like
Speaker:nuclear power
Speaker:plants, meaning
Speaker:they produce a
Speaker:lot of energy
Speaker:with a high
Speaker:energy yield, but
Speaker:a low
Speaker:energy cost.
Speaker:That's when
Speaker:they're in their
Speaker:energetic,
Speaker:optimized state.
Speaker:Okay, so they are
Speaker:nuclear
Speaker:power plants.
Speaker:That would be CDR3.
Speaker:No, no, that's a
Speaker:neutral CDR.
Speaker:That's CDR0,
Speaker:think about it.
Speaker:Okay, all right.
Speaker:That's your, the
Speaker:top part of
Speaker:the wheel.
Speaker:And then what
Speaker:happens is when
Speaker:you initially
Speaker:have a threat, it
Speaker:doesn't have to
Speaker:be a
Speaker:pathogenic threat.
Speaker:It can be a
Speaker:toxin, it can be
Speaker:a heavy metal, it
Speaker:could be
Speaker:psychological
Speaker:threats, it could
Speaker:be persistent
Speaker:organic
Speaker:pollutants.
Speaker:You name it.
Speaker:When there's an
Speaker:initial threat of
Speaker:which the immune
Speaker:system perceives
Speaker:that it needs to
Speaker:create a specific
Speaker:response to, then
Speaker:the mitochondria
Speaker:shift into a
Speaker:CDR1 state.
Speaker:This is where
Speaker:they become more
Speaker:glycolytically
Speaker:dominant.
Speaker:Now, which is
Speaker:very natural, and
Speaker:just by the way,
Speaker:the mitochondria
Speaker:are continually
Speaker:shifting in and
Speaker:out of these
Speaker:different cell
Speaker:danger
Speaker:response states.
Speaker:But it's
Speaker:important that
Speaker:they're able to
Speaker:shift and they
Speaker:don't get stuck.
Speaker:Okay, the reason
Speaker:as to why they
Speaker:get stuck is
Speaker:very, are very
Speaker:complex, because
Speaker:now we're looking
Speaker:at an interplay
Speaker:between endocrine
Speaker:and neurological,
Speaker:immunological,
Speaker:which actually
Speaker:there's Leo
Speaker:Prambro, of which
Speaker:we both know of.
Speaker:He also created a
Speaker:category
Speaker:entitled
Speaker:psychoneuroimmunology,
Speaker:which pretty much
Speaker:embodies a lot of
Speaker:this work
Speaker:as well.
Speaker:But he puts it
Speaker:into a construct
Speaker:of not only that
Speaker:of apparent
Speaker:physiology, but
Speaker:also
Speaker:psychological,
Speaker:even spiritual
Speaker:processes, which
Speaker:I'm very much
Speaker:aligned into his
Speaker:theories as well.
Speaker:Yet, we go back
Speaker:to Navio's work,
Speaker:the cell danger
Speaker:one is when you
Speaker:become more
Speaker:glycolytically
Speaker:dominant.
Speaker:So what happens
Speaker:here is that the
Speaker:mitochondria are
Speaker:going to be more
Speaker:readily engaged,
Speaker:augmented,
Speaker:responsive, are
Speaker:gonna be more
Speaker:responsive to
Speaker:within the use of
Speaker:glucose as an
Speaker:energy fuel
Speaker:source, right?
Speaker:Glucose and
Speaker:pyruvate and so
Speaker:on, rather than
Speaker:being able to
Speaker:utilize a vast
Speaker:degree of
Speaker:precursors to
Speaker:pyruvate, such as
Speaker:fats and
Speaker:amino acids.
Speaker:So what happens
Speaker:here is that you
Speaker:create a
Speaker:maladaptive
Speaker:response if you
Speaker:get stuck in the
Speaker:CDR1 state,
Speaker:whereby the
Speaker:mitochondria are
Speaker:like, okay, we
Speaker:need glucose, we
Speaker:need glucose, and
Speaker:you start having
Speaker:increased sugar
Speaker:cravings.
Speaker:And subsequently,
Speaker:this is where it
Speaker:starts, right?
Speaker:And then the
Speaker:increase of sugar
Speaker:cravings can also
Speaker:have an impact on
Speaker:driving down
Speaker:methylation
Speaker:because sugar
Speaker:depletes
Speaker:methyl donors.
Speaker:And this is where
Speaker:it can really
Speaker:become a storm.
Speaker:Not only a
Speaker:cytokine storm,
Speaker:but also a storm
Speaker:on your
Speaker:neurotransmitter
Speaker:makeup.
Speaker:So you start to
Speaker:be able to
Speaker:produce less
Speaker:dopamine, you
Speaker:start to have
Speaker:dysregulated
Speaker:production of
Speaker:serotonin, you
Speaker:start to have
Speaker:exacerbated
Speaker:expression of
Speaker:extracellular
Speaker:glutamate, not
Speaker:intracellular,
Speaker:extracellular
Speaker:glutamate.
Speaker:You start to
Speaker:downregulate your
Speaker:gamma-minipituric
Speaker:acid receptor
Speaker:sensitivity
Speaker:because you're
Speaker:not producing
Speaker:enough of it
Speaker:because the
Speaker:extracellular
Speaker:glutamate is
Speaker:preventing you
Speaker:from doing so.
Speaker:And these are all
Speaker:the unfortunate
Speaker:consequences that
Speaker:occur with
Speaker:habitual excess
Speaker:of sugar intake.
Speaker:Now, this state
Speaker:CDR1 is also
Speaker:associated to an
Speaker:immunological
Speaker:phenotype called
Speaker:TH2 dominant, of
Speaker:which I've just
Speaker:written a
Speaker:book about.
Speaker:And it's a book
Speaker:that will be
Speaker:facing for
Speaker:practitioners as
Speaker:well as for
Speaker:the laymen.
Speaker:So we'll have all
Speaker:the complex words
Speaker:that I've thrown
Speaker:around today.
Speaker:We'll have some
Speaker:words that people
Speaker:understand.
Speaker:And the book for
Speaker:the laymen is
Speaker:entitled
Speaker:"Responsible
Speaker:Living, Moving
Speaker:Away From
Speaker:Reactivity."
Speaker:And this is
Speaker:really important
Speaker:because our
Speaker:bodies have
Speaker:veered into
Speaker:states of
Speaker:reactivity
Speaker:without us even
Speaker:realizing it.
Speaker:And the CDR1,
Speaker:when we get stuck
Speaker:here, we also
Speaker:propensiate the
Speaker:release of
Speaker:histamine, which
Speaker:creates fibrosis,
Speaker:which causes poor
Speaker:microvasculature,
Speaker:which does not
Speaker:enable things
Speaker:such as an
Speaker:example, thyroid
Speaker:hormone, from
Speaker:being able to
Speaker:reach certain
Speaker:receptors in the
Speaker:mitochondrial
Speaker:space to induce
Speaker:support of
Speaker:oxidant-phosphorylated
Speaker:pathways, which
Speaker:thyroid hormone
Speaker:is highly
Speaker:responsible
Speaker:for doing.
Speaker:Start protein
Speaker:expression and
Speaker:all of that.
Speaker:Exactly right,
Speaker:exactly right.
Speaker:So this is CDR1.
Speaker:And often people
Speaker:get stuck here
Speaker:because, again,
Speaker:when we're young
Speaker:and our DNA can
Speaker:replicate at a
Speaker:quicker pace, we
Speaker:can recover.
Speaker:But as soon as we
Speaker:get to like 33,
Speaker:that varies from
Speaker:person to person.
Speaker:That's the first
Speaker:switch that
Speaker:occurs as to when
Speaker:our DNA
Speaker:replication
Speaker:starts to
Speaker:slow down.
Speaker:And this is where
Speaker:we have an
Speaker:increase of
Speaker:senescence
Speaker:starting
Speaker:to come up.
Speaker:And then
Speaker:obviously that
Speaker:proliferates as
Speaker:we get over the
Speaker:age of 55, it
Speaker:really
Speaker:proliferates.
Speaker:So in our current
Speaker:time, when you're
Speaker:young, 20s and
Speaker:you're a
Speaker:youngster, you
Speaker:don't feel it as
Speaker:much, but without
Speaker:a doubt, you're
Speaker:being exposed to
Speaker:it and you'll
Speaker:start to
Speaker:feel it later.
Speaker:And it's been
Speaker:reported that
Speaker:those who were
Speaker:born in our
Speaker:generation may
Speaker:not even live as
Speaker:long as our
Speaker:parents'
Speaker:generation,
Speaker:right?
Speaker:Despite the
Speaker:medical
Speaker:advancements.
Speaker:And there's
Speaker:obviously, it's a
Speaker:polarized
Speaker:perspective,
Speaker:again, the
Speaker:courses of
Speaker:polarity,
Speaker:but it does make
Speaker:consideration as
Speaker:to where it is.
Speaker:And these
Speaker:suggestive
Speaker:probabilities
Speaker:that would come
Speaker:about just by
Speaker:opinion, that
Speaker:came about from
Speaker:actually looking
Speaker:into the increase
Speaker:of
Speaker:non-conventional
Speaker:disease and the
Speaker:subsequent
Speaker:shortening of
Speaker:lifespan,
Speaker:depending
Speaker:upon that.
Speaker:And also
Speaker:financial
Speaker:constraints that
Speaker:come about with
Speaker:non-conventional
Speaker:disease, because
Speaker:it's one thing to
Speaker:have medical
Speaker:advancements, but
Speaker:it's another
Speaker:thing to
Speaker:look at, right?
Speaker:So we're actually
Speaker:living in a very
Speaker:interesting time
Speaker:where we have a
Speaker:lot of
Speaker:innovation, but
Speaker:yet we're still
Speaker:exposed to the
Speaker:onslaught of
Speaker:continual stress.
Speaker:Now, one of the
Speaker:bigger stressors
Speaker:that I think is
Speaker:not considered
Speaker:are the unseen
Speaker:stressors
Speaker:like EMF.
Speaker:Without a doubt,
Speaker:non-native EMF is
Speaker:by far the
Speaker:biggest toxin of
Speaker:our age, by far.
Speaker:Without a doubt,
Speaker:there's a-- Ooh,
Speaker:there's a
Speaker:decisive
Speaker:statement.
Speaker:Yeah, absolutely.
Speaker:And I'm also,
Speaker:like I mentioned
Speaker:before, be
Speaker:careful when you
Speaker:have people
Speaker:saying, decisive
Speaker:statements in
Speaker:this instance,
Speaker:and I'm very,
Speaker:very, very
Speaker:critical of being
Speaker:objective.
Speaker:But in this
Speaker:instance, I am
Speaker:passionately
Speaker:committed to the
Speaker:statement that
Speaker:non-native EMF is
Speaker:by far the
Speaker:greatest toxin of
Speaker:our age.
Speaker:The influx of
Speaker:patients
Speaker:struggling with
Speaker:chronic fatigue,
Speaker:struggling with
Speaker:different forms
Speaker:of neurodiversity
Speaker:since the
Speaker:introduction of
Speaker:5G towers is very
Speaker:apparent.
Speaker:Not only in my
Speaker:practice, but
Speaker:many other
Speaker:doctors and
Speaker:physicians, which
Speaker:I work in
Speaker:community with,
Speaker:have also
Speaker:experienced the
Speaker:same thing.
Speaker:So in essence,
Speaker:not to go down
Speaker:that rabbit hole,
Speaker:because Alice is
Speaker:waiting with a
Speaker:mad hatcher to
Speaker:really go down
Speaker:the tangent.
Speaker:So just to avoid
Speaker:that tangent, and
Speaker:the point I'm
Speaker:trying to make is
Speaker:we live in a time
Speaker:where we are
Speaker:perpetually
Speaker:exposed to many
Speaker:stressors, more
Speaker:so than what we
Speaker:actually might
Speaker:give credit to,
Speaker:and may give
Speaker:awareness to.
Speaker:And because of
Speaker:this, it is by
Speaker:natural default,
Speaker:because I mean,
Speaker:evolution takes a
Speaker:lot longer than
Speaker:technological
Speaker:evolution
Speaker:has taken.
Speaker:So the
Speaker:mitochondria have
Speaker:adapted pretty
Speaker:well, very
Speaker:quickly, but they
Speaker:still haven't
Speaker:adapted to what
Speaker:it is we expose
Speaker:them to in our
Speaker:current daily
Speaker:basis,
Speaker:current times.
Speaker:So what we're
Speaker:finding, what
Speaker:I've found, and
Speaker:other
Speaker:practitioners as
Speaker:well, is that
Speaker:people can
Speaker:momentarily move
Speaker:out of these
Speaker:states, you know,
Speaker:if they implement
Speaker:all the biohacks
Speaker:and they change
Speaker:their lifestyle
Speaker:and so on, but
Speaker:the older that
Speaker:they get, the
Speaker:more inclined
Speaker:they are to stay
Speaker:stuck in the CDR1
Speaker:state, okay?
Speaker:Which is very
Speaker:closely
Speaker:associated to
Speaker:chronic low grade
Speaker:information.
Speaker:And again, in
Speaker:influencing
Speaker:metabolic
Speaker:resistance,
Speaker:because when the
Speaker:mitochondria
Speaker:become more
Speaker:glycolytically
Speaker:dominant, they
Speaker:can look for
Speaker:glucose.
Speaker:They're not gonna
Speaker:utilize fat
Speaker:effectively.
Speaker:So beta-oxidation
Speaker:goes down, which
Speaker:means you have
Speaker:extracellular
Speaker:ketones
Speaker:propagating,
Speaker:which also causes
Speaker:more lipid
Speaker:peroxidation, and
Speaker:other cumulative
Speaker:issues between
Speaker:cells comes into
Speaker:the equation.
Speaker:So it's quite an
Speaker:intense paradigm,
Speaker:to understand,
Speaker:but it's an
Speaker:important concept
Speaker:to understand.
Speaker:When we get into
Speaker:cell danger two
Speaker:response state,
Speaker:this is where we
Speaker:have a
Speaker:proliferated
Speaker:mTOR.
Speaker:Just one question
Speaker:before we jump
Speaker:into CD2, if
Speaker:that's okay.
Speaker:You mentioned
Speaker:earlier that
Speaker:isolation is
Speaker:potentially,
Speaker:aside from
Speaker:non-native EMFs,
Speaker:of course, is
Speaker:potentially one
Speaker:of the biggest
Speaker:triggers of the
Speaker:slow grade
Speaker:inflammation.
Speaker:Do you think, and
Speaker:I'm just thinking
Speaker:of myself,
Speaker:subjectively from
Speaker:this, when saying
Speaker:this, but when I
Speaker:was younger, I
Speaker:was definitely
Speaker:more able, and
Speaker:this speaks to
Speaker:what you were
Speaker:saying earlier
Speaker:about us really
Speaker:being more
Speaker:gregarious than
Speaker:we think we are,
Speaker:I was really able
Speaker:to function more
Speaker:in a sort of an
Speaker:isolated
Speaker:capacity.
Speaker:I found I wasn't
Speaker:that being
Speaker:isolated, I
Speaker:wasn't subject to
Speaker:feeling the way I
Speaker:do now, which as
Speaker:we talked about,
Speaker:I'm going through
Speaker:some, my own sort
Speaker:of
Speaker:post-phylophoty
Speaker:with COVID,
Speaker:et cetera.
Speaker:And maybe that is
Speaker:a mitigating
Speaker:factor thereof,
Speaker:but sort of
Speaker:almost
Speaker:independently of
Speaker:that, and maybe
Speaker:prior to COVID, I
Speaker:found that the
Speaker:more time I
Speaker:spent alone,
Speaker:as I got older, I
Speaker:would, yeah, I
Speaker:would definitely
Speaker:become more
Speaker:systemically
Speaker:inflamed.
Speaker:My HRV would tend
Speaker:to drop,
Speaker:et cetera.
Speaker:Do you think that
Speaker:there's a sort of
Speaker:a direct, well,
Speaker:that social
Speaker:isolation is
Speaker:going to fuel
Speaker:that CDR1
Speaker:response as well,
Speaker:or at least as we
Speaker:get older, is it
Speaker:going to
Speaker:exacerbate it?
Speaker:I think it's a
Speaker:question of
Speaker:correlation,
Speaker:perpetuating
Speaker:causation.
Speaker:So I don't think
Speaker:it's causation,
Speaker:and it's, I don't
Speaker:think it's a
Speaker:direct causation,
Speaker:but I think it
Speaker:most certainly
Speaker:has a correlate
Speaker:to perpetuating
Speaker:this misaligned
Speaker:immunological
Speaker:expression.
Speaker:So as you
Speaker:mentioned before,
Speaker:when you were
Speaker:younger, being
Speaker:able to be within
Speaker:your own space
Speaker:and be in a state
Speaker:of, I won't say
Speaker:isolation, but in
Speaker:a solitary state,
Speaker:a solitude, that
Speaker:is solitude.
Speaker:That's a better
Speaker:way, because
Speaker:isolation kind of
Speaker:sounds like
Speaker:you're
Speaker:self-flagellating,
Speaker:right?
Speaker:But solitude
Speaker:sounds a
Speaker:lot better.
Speaker:Yeah,
Speaker:it's better.
Speaker:So when you're
Speaker:younger, you're
Speaker:able to stay at a
Speaker:state, well, you
Speaker:may have been
Speaker:able, not
Speaker:everybody, but in
Speaker:your case, you
Speaker:may have stayed
Speaker:at a state of
Speaker:solitude, but yet
Speaker:you're not
Speaker:dealing with
Speaker:spike protein.
Speaker:You're not
Speaker:dealing with
Speaker:possible
Speaker:associated
Speaker:re-expressions of
Speaker:envelope-based
Speaker:viruses.
Speaker:As you get older,
Speaker:by way of being
Speaker:exposed to heavy
Speaker:metals, which we
Speaker:all are, and a
Speaker:patient asked me
Speaker:the other day,
Speaker:"Where did I have
Speaker:exposure to heavy
Speaker:metals?"
Speaker:I'm like, "Where
Speaker:did you not?"
Speaker:Why do you not
Speaker:have exposure to
Speaker:heavy metals in
Speaker:the day which we
Speaker:live in?
Speaker:They're
Speaker:accumulates,
Speaker:they're
Speaker:accumulates.
Speaker:So as we get
Speaker:older, we
Speaker:accumulate
Speaker:toxins, the body
Speaker:accumulates
Speaker:toxins,
Speaker:particularly if
Speaker:we're not in the
Speaker:nurse, how to
Speaker:remove them, and
Speaker:to have,
Speaker:it's super
Speaker:important to be
Speaker:responsible, and
Speaker:at word
Speaker:responsible,
Speaker:meaning the
Speaker:ability to
Speaker:respond to it in
Speaker:today's
Speaker:current times.
Speaker:And what I'm
Speaker:referring to here
Speaker:is taking
Speaker:strategies in and
Speaker:into an habitual
Speaker:aspect, affording
Speaker:the body to be
Speaker:lightened from
Speaker:its environmental
Speaker:toxin load.
Speaker:Things like Epsom
Speaker:salts, baths,
Speaker:things like
Speaker:sauna, okay?
Speaker:And obviously, it
Speaker:is also need to
Speaker:come with certain
Speaker:considerations,
Speaker:not everybody
Speaker:should be doing
Speaker:them either.
Speaker:That's why I'm
Speaker:not making a
Speaker:blanket statement
Speaker:that sauna is the
Speaker:holy grail for
Speaker:everybody.
Speaker:Some were to go
Speaker:into a sauna,
Speaker:particularly
Speaker:those who have a
Speaker:perpetuated
Speaker:CDR1 state.
Speaker:It's just going
Speaker:to, it's going to
Speaker:exacerbate your
Speaker:muscle
Speaker:response, okay?
Speaker:So you need to
Speaker:like, it's
Speaker:contextual, but
Speaker:regardless, those
Speaker:are the instates.
Speaker:When we get to
Speaker:the point where
Speaker:we become highly
Speaker:reactive, we
Speaker:wanna prevent
Speaker:people from
Speaker:getting to that
Speaker:point, okay?
Speaker:When you are at
Speaker:that point, it is
Speaker:likely that
Speaker:you're gonna need
Speaker:a practitioner
Speaker:like myself or my
Speaker:team to come in
Speaker:and guide the
Speaker:process because
Speaker:it's complex,
Speaker:it's very
Speaker:complex.
Speaker:But we don't want
Speaker:you to get there.
Speaker:Like, I don't
Speaker:want to see a
Speaker:billion people.
Speaker:You know, I'd
Speaker:rather see less
Speaker:people, ill and
Speaker:support more
Speaker:people being
Speaker:healthy.
Speaker:Yeah,
Speaker:preventative,
Speaker:okay.
Speaker:So habitual detox
Speaker:needs to be part
Speaker:of every modern
Speaker:day man's
Speaker:routine.
Speaker:We do not, we're
Speaker:not, the society
Speaker:is not going to
Speaker:reduce its toxic
Speaker:assault on us.
Speaker:So long as
Speaker:technology
Speaker:affords a payoff,
Speaker:we're gonna
Speaker:continue to have
Speaker:more toxins.
Speaker:Just make peace
Speaker:with that.
Speaker:Yes, I'm hopeful
Speaker:that humanity's
Speaker:future will
Speaker:afford better
Speaker:practices, but in
Speaker:the meantime,
Speaker:let's not negate
Speaker:the reality of
Speaker:corporations and
Speaker:the effect that
Speaker:they have on the
Speaker:economy, okay?
Speaker:And also that
Speaker:effect in which
Speaker:it has in
Speaker:providing
Speaker:employment across
Speaker:the globe.
Speaker:So we can't
Speaker:discredit all
Speaker:these things.
Speaker:We have to
Speaker:consider these
Speaker:things, and which
Speaker:means that we
Speaker:need to be
Speaker:malleable in what
Speaker:it is that we
Speaker:contribute to our
Speaker:own health.
Speaker:Bringing back
Speaker:again the
Speaker:community
Speaker:consciousness
Speaker:around
Speaker:health, right?
Speaker:Yeah, so now your
Speaker:tolerance in that
Speaker:isolated state in
Speaker:contrast to when
Speaker:you're younger is
Speaker:also fueled not
Speaker:only by the fact
Speaker:that you should
Speaker:be around people,
Speaker:because obviously
Speaker:your spirit is
Speaker:telling you this
Speaker:such, but it's
Speaker:also fueled by
Speaker:the fact that
Speaker:there's certain
Speaker:energetic bodies
Speaker:that we exist
Speaker:within, not only
Speaker:the
Speaker:physical state.
Speaker:And I say that, I
Speaker:think it was
Speaker:Wayne Dyer that
Speaker:mentioned one of
Speaker:his audio books.
Speaker:He had a friend
Speaker:that was a
Speaker:neurologist, and
Speaker:they had to, he
Speaker:went to his home
Speaker:for dinner, and
Speaker:they got into
Speaker:conversation
Speaker:about God, okay?
Speaker:And obviously
Speaker:that word has a
Speaker:lot of meaning
Speaker:for
Speaker:different people,
Speaker:or has meaning
Speaker:for, yeah, has
Speaker:difference of
Speaker:meaning for
Speaker:many people.
Speaker:In any case, so
Speaker:his friend was an
Speaker:atheist, and he
Speaker:said, "No, I
Speaker:don't believe in
Speaker:anything, "but I
Speaker:cannot quantify."
Speaker:See, so he's
Speaker:like, "Okay, so
Speaker:Tommy, "when you
Speaker:open up a man's
Speaker:brain, or the
Speaker:skull, "when you
Speaker:look into the
Speaker:brain, "have you
Speaker:ever witnessed
Speaker:consciousness?"
Speaker:That alone is
Speaker:such a profound
Speaker:realization, and
Speaker:the entire human
Speaker:body regenerates
Speaker:itself every
Speaker:seven, well, over
Speaker:a period of
Speaker:seven years.
Speaker:Okay, so the
Speaker:cellular
Speaker:construct changes
Speaker:every seven
Speaker:years, and yet
Speaker:consciousness--
Speaker:Heart included.
Speaker:Blooded.
Speaker:Cardiac muscle
Speaker:included?
Speaker:Now you're asking
Speaker:me a question, I
Speaker:think so.
Speaker:From my
Speaker:understanding, I
Speaker:think all cells
Speaker:actually
Speaker:recycle over a
Speaker:period of
Speaker:seven years.
Speaker:Cardiac cells, I
Speaker:think actually
Speaker:have a quicker
Speaker:recycling
Speaker:capacity more so
Speaker:than others.
Speaker:Liver and cardiac
Speaker:cells have
Speaker:couldn't actually
Speaker:repair quite
Speaker:quickly,
Speaker:but now you're
Speaker:asking me, I need
Speaker:to look back into
Speaker:my physiology.
Speaker:(Laughing) Yeah, no.
Speaker:Don't remember
Speaker:everything of
Speaker:heart, but
Speaker:nonetheless, all
Speaker:cells, the
Speaker:entire, like some
Speaker:cells, like
Speaker:they're repaired
Speaker:slower than
Speaker:others, but all
Speaker:cells over a
Speaker:seven year period
Speaker:would have
Speaker:changed, would
Speaker:have actually
Speaker:changed.
Speaker:(Laughing) Would have been
Speaker:recycled,
Speaker:regenerated,
Speaker:regenerated,
Speaker:that's what I was
Speaker:looking for,
Speaker:regenerated.
Speaker:So just have that
Speaker:concept in your
Speaker:mind, if your
Speaker:entire construct
Speaker:is gonna be
Speaker:different in
Speaker:seven years from
Speaker:now, which it is,
Speaker:but yet your
Speaker:consciousness is
Speaker:transferred
Speaker:into your new
Speaker:construct.
Speaker:What does
Speaker:that depict?
Speaker:What does
Speaker:that mean?
Speaker:Does it mean that
Speaker:Newtonian concept
Speaker:of physical
Speaker:reality of
Speaker:physics is very
Speaker:much a small
Speaker:vantage point of
Speaker:a greater
Speaker:paradigm?
Speaker:Are we looking
Speaker:now to the realm
Speaker:of quantum?
Speaker:What are we, in
Speaker:essence, in the
Speaker:realm of quantum?
Speaker:We're the space
Speaker:between spaces.
Speaker:What does
Speaker:that mean?
Speaker:We're a thought,
Speaker:we're an idea.
Speaker:And this is when
Speaker:you start to
Speaker:think of your, in
Speaker:this type of
Speaker:manner, and you
Speaker:start to see a
Speaker:human, not as a
Speaker:physical body,
Speaker:but as a spirit
Speaker:having a human
Speaker:experience, you
Speaker:start to see that
Speaker:the spirit comes
Speaker:into experience
Speaker:by way of its
Speaker:desire of
Speaker:education.
Speaker:And it is
Speaker:important that
Speaker:when you start to
Speaker:see a person
Speaker:going through a
Speaker:period of
Speaker:struggle, that
Speaker:you support their
Speaker:education, that
Speaker:you don't try to
Speaker:have them avoid
Speaker:their education,
Speaker:which is where
Speaker:opioids can come
Speaker:into the equation
Speaker:otherwise.
Speaker:And I'm not
Speaker:saying opioids
Speaker:are always wrong,
Speaker:there are
Speaker:instances where
Speaker:they're helpful,
Speaker:but definitely
Speaker:not to the degree
Speaker:of which they're
Speaker:being abused.
Speaker:And this is where
Speaker:the ego, now
Speaker:we're going to
Speaker:the realm of
Speaker:psychology, has
Speaker:the part in
Speaker:trying to
Speaker:captivate its
Speaker:falsehood in
Speaker:your belief
Speaker:in being your
Speaker:God, in being
Speaker:your reality.
Speaker:And in essence,
Speaker:the ego is just a
Speaker:program that we
Speaker:adopt for
Speaker:survival in the
Speaker:physical
Speaker:construct, but it
Speaker:most certainly
Speaker:does not need to
Speaker:define us.
Speaker:And when you
Speaker:don't let it
Speaker:define you,
Speaker:because the ego
Speaker:is also manifest
Speaker:by cultural,
Speaker:societal, and
Speaker:belief
Speaker:systems, right?
Speaker:Which get
Speaker:impressed upon us
Speaker:from the day in
Speaker:which we
Speaker:were born.
Speaker:So it begs the
Speaker:question is what
Speaker:is us and what
Speaker:isn't us?
Speaker:Like are we the
Speaker:narrative that we
Speaker:have adopted?
Speaker:Are we more?
Speaker:And I believe
Speaker:that we're more,
Speaker:I believe in the
Speaker:latter, but it is
Speaker:important to
Speaker:nurse a person's
Speaker:experience so
Speaker:that they can
Speaker:have the life of
Speaker:an elevated life
Speaker:where they're not
Speaker:impacted by the
Speaker:burden of disease
Speaker:and so on, which
Speaker:means that
Speaker:sometimes when
Speaker:somebody's going
Speaker:through shit,
Speaker:it's because they
Speaker:are meant to go
Speaker:through shit.
Speaker:They're meant not
Speaker:to just stay
Speaker:there, but
Speaker:they're meant to
Speaker:go through it.
Speaker:Now you can't go
Speaker:through something
Speaker:if you avoid it.
Speaker:It's like having
Speaker:a tunnel.
Speaker:It's like you're
Speaker:being on a main
Speaker:road and there's
Speaker:a tunnel
Speaker:coming up.
Speaker:And you gotta go
Speaker:through the
Speaker:tunnel to get to
Speaker:the other side
Speaker:and see the
Speaker:daylight again.
Speaker:But you get to
Speaker:the tunnel and
Speaker:instead of going
Speaker:through the
Speaker:tunnel, you just
Speaker:put on all your
Speaker:lights in the car
Speaker:so that you could
Speaker:have some light,
Speaker:but you blind
Speaker:yourself and then
Speaker:you try to go
Speaker:through the
Speaker:tunnel, but you
Speaker:keep on crashing
Speaker:because you have
Speaker:too much light
Speaker:going on in your
Speaker:car because
Speaker:you're not
Speaker:willing to
Speaker:experience a
Speaker:brevity of
Speaker:darkness.
Speaker:Yeah, that
Speaker:makes sense.
Speaker:I think that
Speaker:there's a lot
Speaker:there to unpack.
Speaker:And yeah, it is
Speaker:interesting how
Speaker:we sort of
Speaker:managed to link
Speaker:CDR one up with
Speaker:almost this sort
Speaker:of pseudo concept
Speaker:of free will.
Speaker:I guess.
Speaker:But yeah, getting
Speaker:back to sort of
Speaker:the cell danger
Speaker:response just to
Speaker:sort of tie up
Speaker:this section of
Speaker:the conversation.
Speaker:CDR two
Speaker:specifically, you
Speaker:sort of
Speaker:elucidated that
Speaker:CDR one is where
Speaker:there's a lot of
Speaker:sort of disparity
Speaker:in fuel sources
Speaker:being used and
Speaker:this cell becomes
Speaker:sort of almost
Speaker:more glycolytic
Speaker:and sort of more
Speaker:dependent on
Speaker:those fuel
Speaker:sources and less
Speaker:able to maybe
Speaker:utilize fatty
Speaker:acids if you're,
Speaker:which I think is
Speaker:quite interesting
Speaker:because you
Speaker:oftentimes see
Speaker:people who are
Speaker:unable to fast,
Speaker:unable to sort of
Speaker:utilize ketogenic
Speaker:diets
Speaker:effectively.
Speaker:They're often in
Speaker:this state.
Speaker:Now, it then
Speaker:obviously
Speaker:progresses as you
Speaker:alluded
Speaker:to CDR two.
Speaker:Would you sort of
Speaker:mind sort of
Speaker:carrying on the
Speaker:conversation
Speaker:from there?
Speaker:Yeah, absolutely.
Speaker:So CDR two from a
Speaker:pathological
Speaker:perspective has
Speaker:high association
Speaker:with cancer and
Speaker:PCOS and
Speaker:endometriosis.
Speaker:In essence, where
Speaker:replication or
Speaker:cell cycle arrest
Speaker:starts to become
Speaker:somewhat
Speaker:compromised.
Speaker:So CDR two is
Speaker:when it is a
Speaker:predominant mTOR
Speaker:state and not
Speaker:enough of an AMPK
Speaker:reactive state.
Speaker:So this is where
Speaker:mitochondria
Speaker:become highly
Speaker:saturated.
Speaker:Okay, so if one
Speaker:is stuck in a CDR
Speaker:two, let's
Speaker:understand from
Speaker:the natural way
Speaker:in which this
Speaker:whole sequence of
Speaker:events is meant
Speaker:to unfold is that
Speaker:when you
Speaker:initially have a
Speaker:threat, you
Speaker:induce
Speaker:inflammation,
Speaker:which by way of
Speaker:increasing the
Speaker:activity of
Speaker:glycolysis,
Speaker:you're gonna
Speaker:increase
Speaker:extracellular ATP
Speaker:quite rapidly.
Speaker:That
Speaker:extracellular ATP
Speaker:fills the
Speaker:response of the
Speaker:innate system,
Speaker:but also then
Speaker:triggers the
Speaker:adaptive immune
Speaker:system to create
Speaker:replication,
Speaker:plonal
Speaker:replication,
Speaker:okay.
Speaker:And then you get
Speaker:into the CDR two.
Speaker:Now the CDR two,
Speaker:you have again,
Speaker:it's glycolysis
Speaker:as well as your
Speaker:oxidase or
Speaker:phosphorylated
Speaker:systems that
Speaker:start to kick in.
Speaker:But they kick in
Speaker:in a more of a
Speaker:predominance mTOR
Speaker:fashion for
Speaker:recovery, okay,
Speaker:for recovery
Speaker:because CDR one,
Speaker:inflammation
Speaker:damages tissue.
Speaker:CDR two, the
Speaker:recovery of that
Speaker:damaged tissue
Speaker:needs to take
Speaker:place, okay.
Speaker:And then CDR
Speaker:three, if you're
Speaker:there, this is
Speaker:when you're
Speaker:nucleotide, your
Speaker:production of
Speaker:NAD, FAD, this
Speaker:starts to ramp up
Speaker:to support
Speaker:electron
Speaker:transport chain.
Speaker:Okay, but if you
Speaker:get stuck in a
Speaker:CDR three, it's
Speaker:because there is
Speaker:compromise in the
Speaker:phosphate
Speaker:systems.
Speaker:Not to support
Speaker:the electron
Speaker:transport chain.
Speaker:So this is
Speaker:where like,
Speaker:that autism is
Speaker:indicative
Speaker:of CDR three.
Speaker:Okay, so you have
Speaker:optimal oxidative
Speaker:phosphorylation,
Speaker:but you don't
Speaker:have enough of
Speaker:the spark because
Speaker:your glycolysis
Speaker:lights that
Speaker:bonfire to keep
Speaker:the mitochondria
Speaker:in an anhydrous
Speaker:state,
Speaker:catabolic state.
Speaker:If you don't have
Speaker:enough of that
Speaker:glycolytic
Speaker:reaction
Speaker:occurring, then
Speaker:the mitochondria,
Speaker:although their
Speaker:nucleotide
Speaker:reactions can be
Speaker:optimal through
Speaker:oxidative
Speaker:phosphorylation,
Speaker:subsequent
Speaker:availability of
Speaker:things like NAD
Speaker:would be
Speaker:massively
Speaker:declined because
Speaker:sequence of in
Speaker:the production of
Speaker:NAD is also
Speaker:highly reliant on
Speaker:glycolysis
Speaker:as well.
Speaker:And this is where
Speaker:something like
Speaker:the thylene blue
Speaker:would come in as
Speaker:an electron dolib
Speaker:because it's
Speaker:obviously able to
Speaker:bypass some of
Speaker:those complexes
Speaker:that are being
Speaker:blocked, is that
Speaker:correct?
Speaker:In part, yes, but
Speaker:most certainly
Speaker:the first and the
Speaker:third complexes,
Speaker:but it also can
Speaker:come into
Speaker:the CDR one.
Speaker:Let me
Speaker:explain why.
Speaker:So the CDR one
Speaker:will trigger a
Speaker:macrophage to
Speaker:induce a
Speaker:hepcidin, an
Speaker:increase of
Speaker:hepcidin
Speaker:activity, which
Speaker:basically affords
Speaker:their consumption
Speaker:of iron, thereby
Speaker:increasing their
Speaker:nature from an
Speaker:anti-inflammatory
Speaker:state to a
Speaker:radical state, in
Speaker:perpetuating
Speaker:their
Speaker:pro-inflammatory
Speaker:activity in the
Speaker:body, which by
Speaker:means of
Speaker:increasing
Speaker:attraction toward
Speaker:a particular site
Speaker:is highly
Speaker:feasible and also
Speaker:productive.
Speaker:So the macrophage
Speaker:in compromising,
Speaker:so by
Speaker:compromising
Speaker:iron,
Speaker:by creating an
Speaker:excess of
Speaker:extracellular
Speaker:iron as well not
Speaker:being made
Speaker:available for the
Speaker:health of red
Speaker:blood cells and
Speaker:so on, has a
Speaker:negative knock-on
Speaker:impact onto the
Speaker:pentose phosphate
Speaker:cycle, which also
Speaker:has a depleto
Speaker:factor on NADPH
Speaker:availability.
Speaker:So in these
Speaker:instances, iron
Speaker:is incredibly
Speaker:important for
Speaker:oxidative
Speaker:phosphorylation,
Speaker:incredibly,
Speaker:particularly with
Speaker:those particular
Speaker:oxidative
Speaker:phosphorylated
Speaker:points,
Speaker:those stages.
Speaker:So methylene blue
Speaker:comes into the
Speaker:equation by
Speaker:firstly reducing
Speaker:the release of
Speaker:hepcidin, also by
Speaker:neutralizing the
Speaker:reactivity of
Speaker:these monocytes,
Speaker:all the while
Speaker:even in an
Speaker:iron-depleted
Speaker:state, which most
Speaker:viral incidences
Speaker:can actually
Speaker:induce, it still
Speaker:supports the
Speaker:mechanisms of
Speaker:which get shut
Speaker:down when one
Speaker:goes into a
Speaker:predominant
Speaker:glycolytic state.
Speaker:So methylene blue
Speaker:can, most
Speaker:certainly, it's a
Speaker:versatile
Speaker:molecule that can
Speaker:be utilized in
Speaker:multiple CDR
Speaker:states, but
Speaker:specifically CDR1
Speaker:and CDR3, it is
Speaker:highly beneficial
Speaker:to incorporate
Speaker:its use.
Speaker:Okay, and just
Speaker:one follow-up
Speaker:from that, and
Speaker:I've just been
Speaker:going through
Speaker:this, trying to
Speaker:understand this
Speaker:concept of
Speaker:ferroptosis,
Speaker:sort of
Speaker:pre-programmed,
Speaker:form of
Speaker:pre-programmed
Speaker:cell death that
Speaker:is driven by sort
Speaker:of, I believe,
Speaker:characterized by
Speaker:iron-dependent
Speaker:accumulation in
Speaker:lipid peroxides.
Speaker:Now,
Speaker:loosely with
Speaker:methylene blue,
Speaker:and I'm just
Speaker:trying to link
Speaker:this together on
Speaker:the fly here, so
Speaker:I might be
Speaker:completely
Speaker:off base,
Speaker:would you
Speaker:potentially
Speaker:utilize methylene
Speaker:blue when there's
Speaker:this sort of
Speaker:heightened
Speaker:presence of
Speaker:ferroptosis?
Speaker:Absolutely, it
Speaker:would propensiate
Speaker:it, for sure.
Speaker:Actually, it
Speaker:propensiates ever
Speaker:more, so it
Speaker:wouldn't
Speaker:inhibit it.
Speaker:It would actually
Speaker:propensiate that
Speaker:particular
Speaker:activity of
Speaker:ferroptosis, for sure.
Speaker:Okay.
Speaker:Yeah.
Speaker:All right,
Speaker:okay, good.
Speaker:I'm glad I
Speaker:vaguely got
Speaker:something
Speaker:right today.
Speaker:Yep, we have to
Speaker:ask stuff, what
Speaker:is the process of
Speaker:ferroptosis
Speaker:actually
Speaker:inducing?
Speaker:A form of
Speaker:apoptosis or a
Speaker:necrosis.
Speaker:Exactly,
Speaker:apoptosis,
Speaker:hopefully not
Speaker:necrosis, but
Speaker:apoptosis,
Speaker:for sure.
Speaker:And what
Speaker:methylene blue
Speaker:will actually do
Speaker:is fuel that
Speaker:process of
Speaker:autophagy to
Speaker:occur by way in
Speaker:which it actually
Speaker:modulates
Speaker:oxidative
Speaker:phosphorylated
Speaker:pathways to
Speaker:ensure the
Speaker:continual supply
Speaker:of energy that's
Speaker:required during
Speaker:processes of
Speaker:autophagy.
Speaker:Okay, I think
Speaker:I've got that.
Speaker:That's, yeah,
Speaker:I've got it good.
Speaker:If you think
Speaker:about the
Speaker:difference
Speaker:between
Speaker:catecholamine,
Speaker:dorbicorticoids,
Speaker:and
Speaker:insulin, okay.
Speaker:So insulin brings
Speaker:things into the
Speaker:cell,
Speaker:dorbicorticoids,
Speaker:catecholamine
Speaker:release things
Speaker:from the cell.
Speaker:Okay, so when we
Speaker:are looking to,
Speaker:(Laughs)
Speaker:I'm trying to
Speaker:simplify
Speaker:something very
Speaker:complex.
Speaker:(Laughs) Sorry, sorry,
Speaker:this is
Speaker:completely
Speaker:my fault.
Speaker:We've gone off on
Speaker:a tangent.
Speaker:No, not at all,
Speaker:not at all.
Speaker:When we are
Speaker:looking to break
Speaker:particles down,
Speaker:we need somewhat
Speaker:of a catalytic
Speaker:reaction to
Speaker:occur, okay.
Speaker:In order for a
Speaker:catalytic action
Speaker:to occur, we need
Speaker:availability
Speaker:of ATP.
Speaker:So we need to be able to do that
Speaker:in the most
Speaker:basic sense.
Speaker:So in an increase
Speaker:of ferroptosis,
Speaker:you're most
Speaker:certainly
Speaker:inducing an
Speaker:oxidative state
Speaker:in the
Speaker:body, okay.
Speaker:That's pretty
Speaker:much what it
Speaker:does, and from
Speaker:that, apoptosis
Speaker:shouldn't ensue.
Speaker:And high dose
Speaker:vitamin C by way
Speaker:is a way of
Speaker:inducing
Speaker:ferroptosis.
Speaker:Yeah, that's one
Speaker:of the, that's
Speaker:one of, and
Speaker:people didn't
Speaker:realize this for
Speaker:such a long time
Speaker:when they were
Speaker:like, you know,
Speaker:using high dose
Speaker:vitamin C and was
Speaker:working
Speaker:for cancer.
Speaker:It's actually
Speaker:because it
Speaker:induces an
Speaker:oxidative state
Speaker:in order for the
Speaker:body to
Speaker:upregulate
Speaker:certain regions
Speaker:of lymphocyte
Speaker:response.
Speaker:This is why it
Speaker:regenerates
Speaker:lymphocytes.
Speaker:Vitamin C is well
Speaker:known to
Speaker:regenerate such
Speaker:toxic lymphocytes
Speaker:that have become
Speaker:exhausted, high
Speaker:dose vitamin C.
Speaker:And it's by way,
Speaker:in part, by way
Speaker:of this oxidative
Speaker:process through
Speaker:ferroptosis that
Speaker:this occurs.
Speaker:So in order for
Speaker:this to continue
Speaker:to provide
Speaker:its process of
Speaker:apoptosis
Speaker:support, there is
Speaker:a needed
Speaker:availability of
Speaker:energy that comes
Speaker:into the
Speaker:equation, not
Speaker:only to fuel
Speaker:this, but also to
Speaker:mitigate the
Speaker:excess of
Speaker:radicals that can
Speaker:also create an
Speaker:unwanted effect
Speaker:onto neighboring
Speaker:tissues, which
Speaker:whereby, if this
Speaker:wasn't there, the
Speaker:likelihood of
Speaker:necrosis would be
Speaker:a greater
Speaker:probability.
Speaker:So we don't want,
Speaker:you know,
Speaker:necrotic tissue
Speaker:to accumulate.
Speaker:We want the
Speaker:breakdown and the
Speaker:regeneration, the
Speaker:optimal cell
Speaker:cycle arrest or a
Speaker:cyclo-renewal
Speaker:state to come
Speaker:into the, to into
Speaker:expression.
Speaker:This is where
Speaker:methylene blue,
Speaker:in specific
Speaker:cases, most
Speaker:certainly can
Speaker:improve upon the
Speaker:likelihood of
Speaker:this actually
Speaker:occurring.
Speaker:The consideration
Speaker:to methylene blue
Speaker:is the
Speaker:availability
Speaker:to NADPH.
Speaker:Okay.
Speaker:If there is an
Speaker:insufficient
Speaker:availability of
Speaker:NADPH, which is
Speaker:predominantly
Speaker:fueled through
Speaker:the activity of
Speaker:the
Speaker:pentose-phosphate
Speaker:pathway, then
Speaker:you're going to
Speaker:have an excess of
Speaker:extracellular
Speaker:methylene blue,
Speaker:not leukolucalene
Speaker:blue, but
Speaker:extracellular
Speaker:methylene blue
Speaker:accumulate, which
Speaker:again-- It's the
Speaker:thiamine.
Speaker:Yeah, the
Speaker:thiamine, the
Speaker:thiamine supports
Speaker:the
Speaker:pentose-phosphate
Speaker:pathway.
Speaker:There are other
Speaker:elements that do
Speaker:as well.
Speaker:There are a lot,
Speaker:but the thiamine,
Speaker:as far as a focal
Speaker:point is
Speaker:concerned,
Speaker:propensiates a
Speaker:lot of the PPP
Speaker:activity.
Speaker:So in these
Speaker:constructs
Speaker:between the
Speaker:pentose-phosphate
Speaker:pathway NADPH,
Speaker:NAD, when there
Speaker:isn't enough
Speaker:NADPH to
Speaker:complement the
Speaker:activity of NAD,
Speaker:then leukocytes
Speaker:lose their
Speaker:capacity to
Speaker:integrate from a
Speaker:metabolomic level
Speaker:methylene blue
Speaker:into their
Speaker:construct, which
Speaker:is mostly the
Speaker:reason as to
Speaker:where, as a
Speaker:dichromatic
Speaker:material,
Speaker:methylene blue
Speaker:provides
Speaker:antioxidant
Speaker:support.
Speaker:So it's both an
Speaker:oxidative
Speaker:potentiator as
Speaker:well as an
Speaker:antioxidant
Speaker:potentiator.
Speaker:And in order for
Speaker:it to be
Speaker:balanced, in
Speaker:order for it to
Speaker:have a modulated
Speaker:effect on the
Speaker:body, the
Speaker:subsequent
Speaker:availability of
Speaker:NADPH is highly,
Speaker:highly, highly
Speaker:important.
Speaker:And this is
Speaker:something like
Speaker:anybody that's
Speaker:going through
Speaker:like CDO1 or
Speaker:CDO3, that's
Speaker:looking to, considering
Speaker:utilizing
Speaker:methylene blue,
Speaker:really first
Speaker:thing is to look
Speaker:into the state of
Speaker:their spleen,
Speaker:their specific
Speaker:markers that can
Speaker:give you
Speaker:indication of
Speaker:that MPV, ESR.
Speaker:When there's
Speaker:instance of
Speaker:splenic
Speaker:insufficiency,
Speaker:first, make sure
Speaker:that at the same
Speaker:time that you are
Speaker:supplementing
Speaker:with methylene
Speaker:blue, that you're
Speaker:supporting the
Speaker:PPP with
Speaker:necessary
Speaker:co-factors.
Speaker:And then this
Speaker:will help to
Speaker:mitigate the
Speaker:likelihood of
Speaker:unwanted side
Speaker:effect through
Speaker:the use of
Speaker:methylene blue.
Speaker:It's the same
Speaker:thing with ozone
Speaker:therapy.
Speaker:Ozone therapy is
Speaker:incredible.
Speaker:It most
Speaker:certainly, I
Speaker:mean, it does so
Speaker:many things.
Speaker:I'm just trying
Speaker:to say
Speaker:what it does.
Speaker:It's like, I will
Speaker:take another
Speaker:podcast.
Speaker:Yet, if you were
Speaker:to administer
Speaker:ozone therapy,
Speaker:eventually, I
Speaker:mean, there are
Speaker:certain instances
Speaker:where it requires
Speaker:more application,
Speaker:like for example,
Speaker:Lyme disease
Speaker:and cancer.
Speaker:But that's also
Speaker:because the
Speaker:metabolic state
Speaker:thus deems its
Speaker:necessity based
Speaker:upon what these
Speaker:particular
Speaker:constructs do to
Speaker:immunomatabolism.
Speaker:In situations
Speaker:outside of that
Speaker:construct, if you
Speaker:were to use ozone
Speaker:therapy every
Speaker:day, it's not
Speaker:gonna be very
Speaker:healthy for you.
Speaker:It's the same
Speaker:with
Speaker:methylene blue.
Speaker:Same with
Speaker:methylene blue.
Speaker:It most certainly
Speaker:can be utilized
Speaker:on a daily basis
Speaker:depending upon
Speaker:the content,
Speaker:sorry, the
Speaker:context, the
Speaker:context as to
Speaker:where you're
Speaker:using the
Speaker:methylene blue
Speaker:content
Speaker:within, right?
Speaker:So I'm going off
Speaker:on the tangent of
Speaker:methylene blue,
Speaker:but it does bring
Speaker:you to what it
Speaker:was talking
Speaker:about,
Speaker:immunomatabolism
Speaker:and dichromatic
Speaker:materials.
Speaker:Kirkman is
Speaker:another
Speaker:dichromatic
Speaker:material, by the
Speaker:way, but also
Speaker:plays incredible
Speaker:vantage role in
Speaker:mitigating
Speaker:astrogliosis in
Speaker:the brain,
Speaker:thus reducing the
Speaker:potential buildup
Speaker:of amyloid
Speaker:plaques as well
Speaker:as modulating
Speaker:cineclic protein,
Speaker:ensuring that the
Speaker:misfolding of
Speaker:those proteins
Speaker:don't ensue
Speaker:within the
Speaker:certain regions
Speaker:of the brain.
Speaker:So these are all,
Speaker:these dichromatic
Speaker:materials are
Speaker:credible, but too
Speaker:much Kirkman in
Speaker:certain
Speaker:individuals that
Speaker:have compromised
Speaker:in their modamine
Speaker:oxidase activity
Speaker:or in their
Speaker:phenol breakdown,
Speaker:which has a lot
Speaker:to do actually
Speaker:with gluten
Speaker:intolerance.
Speaker:So those who have
Speaker:like severe
Speaker:gluten
Speaker:intolerance, if
Speaker:you give them a
Speaker:high dose of
Speaker:Kirkman, there's
Speaker:a likelihood that
Speaker:the phenol load
Speaker:in the Kirkman
Speaker:may cause
Speaker:anxiety.
Speaker:Just on Kirkman
Speaker:quickly, have you
Speaker:ever seen any
Speaker:issues,
Speaker:particularly with
Speaker:Kirkman and
Speaker:overly inhibiting
Speaker:5-alpha
Speaker:reductase?
Speaker:Obviously that's
Speaker:another tangent
Speaker:of the rabbit
Speaker:hole, but some
Speaker:people are going
Speaker:to be more
Speaker:sensitive to the
Speaker:inhibition of
Speaker:that enzyme than
Speaker:say others.
Speaker:Do you think, and
Speaker:the whole
Speaker:post-menastride
Speaker:argument is a
Speaker:completely
Speaker:different
Speaker:conversation, I
Speaker:apologize to the
Speaker:audience because
Speaker:we've now gone on
Speaker:rabbit holes, but
Speaker:rabbit holes.
Speaker:However, do you
Speaker:think
Speaker:some of these
Speaker:nutrients to call
Speaker:compounds,
Speaker:high dose
Speaker:riboflavin, zinc,
Speaker:et cetera, what
Speaker:are the other
Speaker:ones, the lion's
Speaker:mane, can
Speaker:potentiate some
Speaker:of these issues
Speaker:that the same
Speaker:class of drug
Speaker:acting on the
Speaker:same receptor
Speaker:can, or do you
Speaker:not see that to
Speaker:be an issue
Speaker:clinically
Speaker:speaking?
Speaker:I guess the
Speaker:Kirkman,
Speaker:resveratrol,
Speaker:there are a
Speaker:couple of others
Speaker:that have an
Speaker:impact on 5-alpha
Speaker:reductase.
Speaker:Some have also
Speaker:reported that it
Speaker:can have an
Speaker:impact on free
Speaker:androgen levels
Speaker:as well in that
Speaker:activity.
Speaker:When you look
Speaker:into the pharma
Speaker:dynamics,
Speaker:you'll see that
Speaker:it really is
Speaker:dependent upon
Speaker:specific genetic
Speaker:probabilities
Speaker:into enzyme
Speaker:function as to
Speaker:how the person
Speaker:breaks down these
Speaker:particular
Speaker:molecules, which
Speaker:is quite
Speaker:interesting
Speaker:because those who
Speaker:have a propensity
Speaker:for a slower
Speaker:caffeine
Speaker:metabolism as an
Speaker:example, which
Speaker:also has certain
Speaker:similarity of
Speaker:enzymatic
Speaker:interaction as to
Speaker:how the liver
Speaker:breaks down
Speaker:Kirkman or
Speaker:resveratrol.
Speaker:In these
Speaker:instances, these
Speaker:people also have
Speaker:a greater
Speaker:tendency for
Speaker:estrogen
Speaker:dominance, not
Speaker:always, but they
Speaker:generally have,
Speaker:sorry, they often
Speaker:have a propensity
Speaker:for more estrogen
Speaker:dominance.
Speaker:So it begs the
Speaker:question of
Speaker:what's going on
Speaker:within certain
Speaker:methylation
Speaker:sequences
Speaker:depending upon
Speaker:the individual,
Speaker:and as to what
Speaker:impact this is
Speaker:having on
Speaker:modification
Speaker:rates and the
Speaker:different
Speaker:modification
Speaker:rates as well.
Speaker:So it's
Speaker:contextual, and
Speaker:this is where the
Speaker:incorporation of
Speaker:inductive
Speaker:reasoning is
Speaker:highly, highly
Speaker:important because
Speaker:when we take a
Speaker:deductive
Speaker:paradigm,
Speaker:Kirkman's great
Speaker:for everybody.
Speaker:Let's see, is it
Speaker:for neural
Speaker:formation?
Speaker:Well, no, it
Speaker:might be good for
Speaker:a lot because
Speaker:even in
Speaker:longitudinal
Speaker:studies, the
Speaker:majority of
Speaker:people had to
Speaker:respond
Speaker:positively to
Speaker:Kirkman, but the
Speaker:majority is not
Speaker:everyone.
Speaker:So you can't make
Speaker:this definitive
Speaker:statement and a
Speaker:blanket statement
Speaker:saying, "You
Speaker:know, Kirkman,
Speaker:you're good for
Speaker:everybody."
Speaker:And it can
Speaker:actually backfire
Speaker:because in
Speaker:Kirkman's
Speaker:activity in
Speaker:mitigating
Speaker:astrogliosis,
Speaker:as well as
Speaker:expressing more
Speaker:sirtuin activity,
Speaker:there are many
Speaker:things as to what
Speaker:kookanoids do in
Speaker:the body and for
Speaker:the
Speaker:immune system.
Speaker:One of the things
Speaker:in which it does
Speaker:is also inhibit
Speaker:C-X-C-L
Speaker:complexes, C-C-L
Speaker:complexes,
Speaker:which are also
Speaker:sort of chemokine
Speaker:subsets within
Speaker:the immune
Speaker:system itself.
Speaker:And in doing so,
Speaker:it can actually
Speaker:reduce this
Speaker:auto-reactivity
Speaker:of monocytes that
Speaker:I spoke about
Speaker:before in the way
Speaker:in which they
Speaker:hijack our iron,
Speaker:thereby becoming
Speaker:super-sproxidated
Speaker:radicals.
Speaker:So Kirkman can
Speaker:actually mitigate
Speaker:that from
Speaker:happening, but in
Speaker:instances whereby
Speaker:it can compromise
Speaker:through the
Speaker:antigen to
Speaker:estrogen ratio
Speaker:availability, and
Speaker:this is very
Speaker:much, it's not
Speaker:the, I just have
Speaker:to make this
Speaker:statement, is
Speaker:that we're not
Speaker:dealing with a
Speaker:majority here.
Speaker:In this
Speaker:statement, we are
Speaker:dealing with
Speaker:outliers, but
Speaker:outliers
Speaker:also matter.
Speaker:So generally,
Speaker:most people
Speaker:respond very well
Speaker:to Kirkman and it
Speaker:helps immune
Speaker:system
Speaker:multi-levels, but
Speaker:those whom do
Speaker:have a disparity
Speaker:or do develop a
Speaker:disparity in the
Speaker:ratio between
Speaker:testosterone and
Speaker:estrogen
Speaker:through its use
Speaker:can also actually
Speaker:thereby
Speaker:propensiate more
Speaker:histamine release
Speaker:because estrogen
Speaker:out of all our
Speaker:sex hormones is
Speaker:the hormone that
Speaker:propensiates
Speaker:histamine release
Speaker:more so than any
Speaker:other hormone.
Speaker:And this is also
Speaker:a reason why
Speaker:estrogen is more,
Speaker:I don't like to
Speaker:use the word
Speaker:important,
Speaker:has more of an
Speaker:active role,
Speaker:there we go.
Speaker:You can see I
Speaker:don't like
Speaker:hierarchy.
Speaker:(Laughs)
Speaker:I try to avoid
Speaker:these words at
Speaker:all costs.
Speaker:It's good, it
Speaker:challenges my
Speaker:vocabulary.
Speaker:So it has more of
Speaker:an active role in
Speaker:modulating one's
Speaker:libido, more so
Speaker:in testosterone,
Speaker:because people
Speaker:aren't
Speaker:aware of this.
Speaker:Most people think
Speaker:testosterone is
Speaker:the hormone that
Speaker:actually is
Speaker:estrogen.
Speaker:And the reason is
Speaker:to, one of the
Speaker:reasons as to why
Speaker:estrogen, it
Speaker:propensiates
Speaker:histamine
Speaker:receptors
Speaker:in the brain
Speaker:by way of its
Speaker:impact in causing
Speaker:the release of
Speaker:histamine,
Speaker:propensiating the
Speaker:release of
Speaker:histamine
Speaker:as well.
Speaker:So if you are in
Speaker:a CDR1 state and
Speaker:you histamine
Speaker:prone, which is
Speaker:what CH2
Speaker:dominance, and
Speaker:there are
Speaker:multiple
Speaker:contributory
Speaker:factors that can
Speaker:actually reduce a
Speaker:CH2 dominant
Speaker:state or CDR1
Speaker:state, which
Speaker:we'll go to
Speaker:in a moment.
Speaker:But if you are in
Speaker:the state, you
Speaker:really wanna take
Speaker:as much
Speaker:precaution
Speaker:within avoiding
Speaker:an estrogen
Speaker:dominant state.
Speaker:Because that
Speaker:estrogen
Speaker:dominance can
Speaker:actually just
Speaker:fuel more of the
Speaker:histamine
Speaker:activity and
Speaker:histamine
Speaker:dominance, and
Speaker:thereby impact
Speaker:other subsequent
Speaker:endocrine
Speaker:systems, such as
Speaker:the thyroid
Speaker:mitochondrial
Speaker:axis as well.
Speaker:So yeah, again,
Speaker:this contextual,
Speaker:the particular
Speaker:genome in
Speaker:question, or the
Speaker:CYP enzyme in
Speaker:question.
Speaker:1A2.
Speaker:Yes, correct,
Speaker:correct.
Speaker:Yeah, Justin,
Speaker:that was again,
Speaker:amazing.
Speaker:I think we're
Speaker:definitely gonna
Speaker:have to have part
Speaker:one, two, and
Speaker:potentially three
Speaker:to this podcast,
Speaker:but it's been an
Speaker:incredible
Speaker:conversation so
Speaker:far, thank you.
Speaker:You're welcome.
Speaker:Okay, I think
Speaker:that really wraps
Speaker:up this whole
Speaker:concept of
Speaker:immunomentabolism.
Speaker:And again, I
Speaker:apologize to the
Speaker:audience.
Speaker:We went on an
Speaker:unknown number of
Speaker:tangents, but I
Speaker:hope it's of some
Speaker:value to you.
Speaker:And in any case,
Speaker:it's definitely
Speaker:been a
Speaker:treat for me.
Speaker:Maybe this is
Speaker:just a selfish
Speaker:reason to
Speaker:podcast.
Speaker:I don't know that
Speaker:I've loved this.
Speaker:Well, happy
Speaker:to oblige.
Speaker:It's been an
Speaker:awesome
Speaker:opportunity to be
Speaker:able to have
Speaker:reciprocity of
Speaker:knowledge share,
Speaker:within
Speaker:knowledge share.
Speaker:Well, I was about
Speaker:to say, you're
Speaker:too kind, and
Speaker:we'll discuss
Speaker:that later.
Speaker:Anyway,
Speaker:so upstream of
Speaker:what causes this
Speaker:dysfunction, you
Speaker:obviously have
Speaker:various systems.
Speaker:And I think the
Speaker:two I'd like to
Speaker:maybe touch on
Speaker:are the gut,
Speaker:because I think
Speaker:it's relatable
Speaker:too for most of
Speaker:the audience,
Speaker:especially people
Speaker:coming from this
Speaker:from a
Speaker:traditional
Speaker:functional
Speaker:medicine
Speaker:standpoint,
Speaker:should we say.
Speaker:I mean, most
Speaker:people view gut
Speaker:dysfunction from
Speaker:the point of
Speaker:lipopolysaccharide
Speaker:ingress, or these
Speaker:so-called
Speaker:endotoxins that
Speaker:create this
Speaker:phenomenon called
Speaker:leaky gut.
Speaker:Actually, I
Speaker:almost got that
Speaker:word right.
Speaker:On test on
Speaker:permeability,
Speaker:whereby these
Speaker:foreign
Speaker:molecules, just
Speaker:broadly speaking,
Speaker:get into
Speaker:circulation
Speaker:through the
Speaker:smaller intestine
Speaker:and drive a lot
Speaker:of inflammation.
Speaker:Now, there's a
Speaker:lot more
Speaker:biochemistry
Speaker:there, obviously,
Speaker:and that's going
Speaker:to sort of
Speaker:subsequently
Speaker:drive a lot of,
Speaker:as you alluded to
Speaker:earlier, HPA-axis
Speaker:dysfunction,
Speaker:which is then
Speaker:going to have
Speaker:this downstream
Speaker:consequence on
Speaker:the immune
Speaker:system, or
Speaker:potentially
Speaker:vice versa.
Speaker:I think you could
Speaker:definitely
Speaker:explain this
Speaker:better than I
Speaker:could, but would
Speaker:you mind just
Speaker:maybe talking us
Speaker:through why this
Speaker:potentially can start off in the
Speaker:gut, this sort of
Speaker:immune
Speaker:dysfunction,
Speaker:this cell danger
Speaker:response?
Speaker:And then maybe we
Speaker:could also then
Speaker:wrap it up with a
Speaker:short
Speaker:conversation
Speaker:about it from an
Speaker:autonomic nervous
Speaker:system
Speaker:standpoint, too.
Speaker:But yeah, we
Speaker:could start there
Speaker:and then go on.
Speaker:That would
Speaker:be great.
Speaker:Absolutely,
Speaker:absolutely.
Speaker:It's interesting
Speaker:to see the
Speaker:microbiome profiling
Speaker:dependent upon
Speaker:the different
Speaker:stages of one's
Speaker:life and the
Speaker:predominance of
Speaker:different
Speaker:species.
Speaker:It's even more
Speaker:interesting when
Speaker:you overlay that
Speaker:mapping as to
Speaker:what particular
Speaker:species ought to
Speaker:be dominant in
Speaker:contrast to those
Speaker:who may be
Speaker:dominant into
Speaker:certain lifestyle
Speaker:factors as well.
Speaker:And I'm not just
Speaker:talking about
Speaker:blatant
Speaker:infarctions.
Speaker:I'm talking about
Speaker:the subtle
Speaker:infarctions.
Speaker:For example,
Speaker:going through a
Speaker:bereavement.
Speaker:Going through a
Speaker:bereavement most
Speaker:certainly has an
Speaker:impact on the
Speaker:limbic system
Speaker:subsequently
Speaker:impacts the
Speaker:gastrointestinal
Speaker:endocrine system,
Speaker:affording
Speaker:opportunity of
Speaker:change of pH
Speaker:variables.
Speaker:And as you
Speaker:alluded to
Speaker:alluded, well,
Speaker:alluded to
Speaker:before, I love
Speaker:the subtle
Speaker:differences of
Speaker:the difference of
Speaker:meaning between
Speaker:words, but as you
Speaker:alluded to before
Speaker:lipopolysaccharides,
Speaker:I actually just
Speaker:finished the
Speaker:dissertation a
Speaker:few years back on
Speaker:lipopolysaccharides
Speaker:and the impact
Speaker:that they have on
Speaker:major depressive
Speaker:disorder.
Speaker:But in my
Speaker:research, there
Speaker:are multiple
Speaker:different
Speaker:mechanisms
Speaker:in which it
Speaker:induced
Speaker:neurodiversity.
Speaker:And again, the
Speaker:reason why I
Speaker:bring up
Speaker:neurodiversity,
Speaker:histamine
Speaker:dominance, CDR1,
Speaker:and its impact on
Speaker:depleting methyl
Speaker:donors as well as
Speaker:availability of
Speaker:iron, it's very,
Speaker:very apparent.
Speaker:And if you don't
Speaker:have these
Speaker:precursors
Speaker:available,
Speaker:they're looking
Speaker:at HVA levels,
Speaker:looking at 5HIA
Speaker:levels, looking
Speaker:at VMA levels.
Speaker:These are all
Speaker:subsequently
Speaker:always impaired
Speaker:in those who have
Speaker:TH2 dominance, or
Speaker:at least
Speaker:one of them.
Speaker:Those are all
Speaker:organic acids for
Speaker:the
Speaker:autososaccharide.
Speaker:Correct, yeah, so
Speaker:your 5HA is an
Speaker:organic acid
Speaker:marker depicting
Speaker:activity of
Speaker:serotonin,
Speaker:which if it's too
Speaker:high, it's also a
Speaker:problem because
Speaker:you might have an
Speaker:excess of
Speaker:peripheral
Speaker:serotonin, which
Speaker:by its nature can
Speaker:certainly induce
Speaker:peripheral, it
Speaker:fuel peripheral
Speaker:inflammation.
Speaker:I mean parasites
Speaker:feed off of
Speaker:serotonin.
Speaker:There's a reason
Speaker:as to why we have
Speaker:more parasitic
Speaker:activity during
Speaker:the full moon,
Speaker:because there's a
Speaker:compromise in
Speaker:terms of the
Speaker:serotonin being
Speaker:methylated into
Speaker:melatonin during
Speaker:that time.
Speaker:Because this is
Speaker:why a lot of
Speaker:your, again, this
Speaker:is also based
Speaker:upon some
Speaker:science, but also
Speaker:functional
Speaker:paradigm science,
Speaker:which it's like
Speaker:the
Speaker:metaphysicians
Speaker:have been
Speaker:alluding to
Speaker:quantum physics
Speaker:well before the
Speaker:scientists jump
Speaker:on board and then
Speaker:they
Speaker:figure it out.
Speaker:So there is some
Speaker:association, but
Speaker:anyway, going
Speaker:back to 5HA,
Speaker:there's an
Speaker:association with
Speaker:serotonin, too
Speaker:much, really bad,
Speaker:too little, also,
Speaker:it's a question
Speaker:of balance.
Speaker:And then your HVA
Speaker:is your
Speaker:homo-banylic
Speaker:acid, which is an
Speaker:indication of
Speaker:dopamine
Speaker:activity.
Speaker:And you've got
Speaker:Dokpak as well,
Speaker:precursor.
Speaker:And then you've
Speaker:got your VMA,
Speaker:which is an
Speaker:indication of
Speaker:nwopin, a front
Speaker:end of the thing.
Speaker:So there are
Speaker:certain nutrient
Speaker:donors required
Speaker:for these
Speaker:enzymatic
Speaker:reactions to
Speaker:take place.
Speaker:Like for example,
Speaker:the production of
Speaker:dopamine, all
Speaker:dopamine,
Speaker:dopamine, and
Speaker:what that
Speaker:requires from the
Speaker:pateratin cycle
Speaker:as an
Speaker:example, right?
Speaker:And what impact
Speaker:that pateratin
Speaker:cycle has on the
Speaker:folate pathway in
Speaker:relation to
Speaker:acetylsomatini
Speaker:and homocysteine.
Speaker:So there's an
Speaker:interplay in this
Speaker:whole makeup, but
Speaker:essence of CDR1,
Speaker:it creates a
Speaker:compromise to
Speaker:that methylation
Speaker:cycling, those
Speaker:methylation
Speaker:wheels, because
Speaker:of the state of
Speaker:our chronic load
Speaker:rate information
Speaker:causing that
Speaker:compromise in the
Speaker:first place.
Speaker:So when we look
Speaker:into the gut in
Speaker:particular,
Speaker:and we see the
Speaker:impact that
Speaker:lipopolysaccharides
Speaker:or the impact
Speaker:that stress can
Speaker:have an impact on
Speaker:the gut affording
Speaker:opportunity to
Speaker:lipopolysaccharides
Speaker:come through, we
Speaker:often notice a
Speaker:decrease of
Speaker:neurotransmitters
Speaker:or availability
Speaker:of
Speaker:neurotransmitters
Speaker:and an expression
Speaker:of cytokines.
Speaker:And also
Speaker:morphological
Speaker:changes that
Speaker:occur in the
Speaker:brain themselves.
Speaker:So the
Speaker:morphological
Speaker:changes are more
Speaker:likely to occur
Speaker:in a perpetuated
Speaker:state of CDR1 or
Speaker:TH2 dominance, or
Speaker:particularly in
Speaker:the developmental
Speaker:stages of an
Speaker:infant's life,
Speaker:kind of the first
Speaker:seven
Speaker:years of life.
Speaker:So this is why
Speaker:even in the
Speaker:uterine
Speaker:considerations of
Speaker:the mother's
Speaker:stress state is
Speaker:highly important
Speaker:to take into
Speaker:consideration.
Speaker:Too much cortisol
Speaker:can actually
Speaker:cause the
Speaker:depletion of
Speaker:certain enzymes
Speaker:that are within
Speaker:the placenta that
Speaker:are meant to be
Speaker:able to contend
Speaker:with that for
Speaker:immunological
Speaker:purposes, thereby
Speaker:actually
Speaker:resulting in an
Speaker:increase of the
Speaker:exposure to the
Speaker:fetus developing
Speaker:brain to
Speaker:cortisol, thereby
Speaker:actually creating
Speaker:morphological
Speaker:changes before
Speaker:the baby's
Speaker:even born.
Speaker:So the reason why
Speaker:I'm bringing up
Speaker:like intrauterine
Speaker:activity and
Speaker:reason why it was
Speaker:regards to the
Speaker:gut is because
Speaker:it's all
Speaker:interconnected.
Speaker:You know, if
Speaker:there's an
Speaker:imbalance of
Speaker:perception, which
Speaker:by way of
Speaker:depletion of
Speaker:certain
Speaker:neurotransmitters
Speaker:that can be
Speaker:induced, that
Speaker:subsequent
Speaker:imbalance is also
Speaker:gonna create
Speaker:somewhat of a
Speaker:threat
Speaker:perception.
Speaker:Now, if the
Speaker:body's in a state
Speaker:of threat
Speaker:perception, as in
Speaker:these monocytes
Speaker:being
Speaker:professionally
Speaker:activated, to try
Speaker:and re-inoculate
Speaker:the body is
Speaker:incredibly
Speaker:difficult.
Speaker:You can probably
Speaker:take all the
Speaker:probiotics
Speaker:in the world.
Speaker:I even had
Speaker:patients of mine
Speaker:whom decided to
Speaker:take on the
Speaker:advice of doctors
Speaker:that have been
Speaker:around for a lot
Speaker:longer
Speaker:than I had.
Speaker:And I had good
Speaker:intentions in
Speaker:these doctors,
Speaker:but they didn't
Speaker:see this
Speaker:particular
Speaker:sequence of--
Speaker:Phenotab.
Speaker:Yeah, they didn't
Speaker:see this paradigm
Speaker:for what it was,
Speaker:so they couldn't
Speaker:conceptualize
Speaker:what this
Speaker:paradigm meant in
Speaker:their efforts.
Speaker:So anyway, these
Speaker:patients spent a
Speaker:lot of money on
Speaker:fecal matter
Speaker:transplant.
Speaker:I'm talking a lot
Speaker:of money.
Speaker:If anybody knows
Speaker:what FMT is, you
Speaker:know, it's not a
Speaker:cheap affair,
Speaker:especially when
Speaker:you're doing it
Speaker:in a clinic,
Speaker:but one of
Speaker:which-- I was
Speaker:about to say, I
Speaker:think most
Speaker:people, there are
Speaker:lots of people,
Speaker:well, not a lot,
Speaker:but I know a few
Speaker:people who sort
Speaker:of go on the DIY
Speaker:route, one might
Speaker:say, and it's not
Speaker:ended, maybe it's
Speaker:a poor pun, but
Speaker:it has not ended
Speaker:up to be a very
Speaker:pretty, with a
Speaker:very
Speaker:pretty ending.
Speaker:So yeah, it's a
Speaker:complete
Speaker:different
Speaker:wheelhouse, as
Speaker:far as I'm
Speaker:concerned.
Speaker:I wouldn't go
Speaker:anywhere near an
Speaker:FMT without very
Speaker:strict
Speaker:supervision.
Speaker:Yeah, you know, I
Speaker:definitely want
Speaker:to do it in a
Speaker:clinic setting.
Speaker:I think there are
Speaker:suppositories and
Speaker:what have that,
Speaker:they're selling
Speaker:at-home kits.
Speaker:The thing is,
Speaker:it's not about
Speaker:just giving the
Speaker:bacteria, whether
Speaker:or not the body
Speaker:receives it.
Speaker:It's like trying
Speaker:to give an organ
Speaker:transplant to a
Speaker:donor that
Speaker:doesn't
Speaker:match the donor.
Speaker:Sorry, to a
Speaker:recipient that
Speaker:doesn't
Speaker:match the donor.
Speaker:So what we need
Speaker:to do, if you
Speaker:just take that
Speaker:comparative
Speaker:situation in
Speaker:terms of the
Speaker:organ donor, and
Speaker:the organ
Speaker:recipient
Speaker:of the donor,
Speaker:we need to
Speaker:improve upon the
Speaker:receptivity of
Speaker:re-inoculation, in
Speaker:re-inoculation.
Speaker:So in order for
Speaker:probiotics to
Speaker:improve upon the
Speaker:microbiome, the
Speaker:immune system
Speaker:needs to be in a
Speaker:state of
Speaker:coherence,
Speaker:not reactivity.
Speaker:With the bodies
Speaker:in the state of
Speaker:hyper-reactivity,
Speaker:when you try to
Speaker:re-inoculate the
Speaker:gut, it's not
Speaker:gonna take hold.
Speaker:So which means
Speaker:that all the gram
Speaker:negative which
Speaker:are more
Speaker:anaerobic in
Speaker:nature are going
Speaker:to continue to
Speaker:perpetuate
Speaker:because the pH is
Speaker:gonna afford
Speaker:their continual
Speaker:activity.
Speaker:Now, it's very
Speaker:important.
Speaker:I love the fact
Speaker:that you brought
Speaker:up the microbiome
Speaker:in the gut
Speaker:because the
Speaker:microbiome
Speaker:expressed 150
Speaker:times more DNA
Speaker:than what our
Speaker:human cells
Speaker:express.
Speaker:So their profile
Speaker:within our bodies
Speaker:has a direct
Speaker:impact on our
Speaker:metabolic
Speaker:respiratory chain
Speaker:efficiency, as in
Speaker:when we have an
Speaker:excess of
Speaker:lipopolysaccharides,
Speaker:given the fact
Speaker:that they're
Speaker:anaerobic nature,
Speaker:can you see how
Speaker:that can link
Speaker:into predominance
Speaker:of glycolysis?
Speaker:Yes, I can.
Speaker:Just getting to
Speaker:feel that
Speaker:inflammatory
Speaker:process, yeah.
Speaker:So it's a
Speaker:question like,
Speaker:where do we go
Speaker:with this?
Speaker:Like where do we
Speaker:start in order to
Speaker:get people
Speaker:feeling healthy
Speaker:again and not
Speaker:having brain fog,
Speaker:not having
Speaker:autoimmune
Speaker:expressions?
Speaker:Lupus, very
Speaker:closely and
Speaker:intimately
Speaker:connected
Speaker:to CDR1.
Speaker:That's the
Speaker:extremes of CDR1.
Speaker:We're extremes of
Speaker:TH2 dominance.
Speaker:So how do we get
Speaker:people away from
Speaker:the potential
Speaker:expressions of
Speaker:these
Speaker:pathological
Speaker:states?
Speaker:And it really
Speaker:comes into seeing
Speaker:the body from a
Speaker:holistic
Speaker:perspective, not
Speaker:throwing that
Speaker:word around as
Speaker:people have, like
Speaker:really
Speaker:understanding the
Speaker:interplay of
Speaker:multiple
Speaker:physiological
Speaker:systems and
Speaker:specifically
Speaker:immunometabolism.
Speaker:See, I didn't, not
Speaker:metabolimmunism, but
Speaker:immunometabolism.
Speaker:And this is, I
Speaker:feel, not just
Speaker:feel, but I also
Speaker:know through
Speaker:clinical
Speaker:experience, a way
Speaker:in which to take
Speaker:people out of the
Speaker:state of dorsal,
Speaker:vagal dominance,
Speaker:which can also
Speaker:have an impact,
Speaker:which does mean,
Speaker:I mean, there's a
Speaker:bidirectional
Speaker:impact on the
Speaker:nervous system as
Speaker:well as immune
Speaker:system,
Speaker:influencing
Speaker:physiological
Speaker:metabolomics.
Speaker:So the gut, yeah,
Speaker:if you're damp,
Speaker:you're gonna have
Speaker:more elaborate
Speaker:polysaccharides.
Speaker:If you're damp,
Speaker:you're gonna have
Speaker:more fungi,
Speaker:meaning more
Speaker:reoccurring
Speaker:Candiases.
Speaker:And everything
Speaker:that that comes
Speaker:with as well, I
Speaker:mean, like just
Speaker:Candida and its
Speaker:own, one of the
Speaker:things that
Speaker:Candida does, one
Speaker:of the things, an
Speaker:increase of
Speaker:pentociety and
Speaker:what this does to
Speaker:the myelin sheath
Speaker:is quite
Speaker:destructive,
Speaker:okay?
Speaker:Not only does it
Speaker:induce the
Speaker:production of
Speaker:pentociety, which
Speaker:destroys the
Speaker:nerve coding,
Speaker:but also
Speaker:subsequently
Speaker:compromises how
Speaker:well the body can
Speaker:use arginine and
Speaker:lysine in
Speaker:doing so.
Speaker:And if anybody
Speaker:knows the
Speaker:importance of
Speaker:lysine in terms
Speaker:of a white blood
Speaker:selectivity
Speaker:against viral
Speaker:threat, when you
Speaker:compromise that,
Speaker:what are you
Speaker:doing to the
Speaker:adaptive
Speaker:immune system?
Speaker:You're tempering
Speaker:it, not tempering
Speaker:it, sorry, you
Speaker:are
Speaker:compromising it.
Speaker:So- Yeah, it's
Speaker:gonna be fairly
Speaker:dissimated.
Speaker:Well, the gut is
Speaker:incredibly
Speaker:important because
Speaker:if you're damp
Speaker:and you've got
Speaker:Candida, you're
Speaker:gonna compromise
Speaker:the adaptive
Speaker:immune system.
Speaker:You're gonna
Speaker:compromise the
Speaker:liver by way in
Speaker:which it
Speaker:increases acetyl
Speaker:aldehyde
Speaker:concentration in
Speaker:the liver, and
Speaker:subsequently
Speaker:there by further
Speaker:compounding
Speaker:methylation,
Speaker:not depletion,
Speaker:but methylation
Speaker:response,
Speaker:compromising the
Speaker:response of
Speaker:methylation by
Speaker:way of inhibiting
Speaker:methionine
Speaker:synthase, which
Speaker:is what acetyl
Speaker:aldehyde does.
Speaker:So there's so
Speaker:many sequences of
Speaker:the gut, but the
Speaker:gut doesn't one
Speaker:day wake up and
Speaker:it's like, okay,
Speaker:you know, I don't
Speaker:like you anymore.
Speaker:Here you go,
Speaker:enjoy a
Speaker:shitty life.
Speaker:Excuse the pun.
Speaker:(Laughs)
Speaker:It happens, and
Speaker:really one needs
Speaker:to venture into
Speaker:considering the
Speaker:Barker
Speaker:hypothesis.
Speaker:Within the Barker
Speaker:hypothesis, it
Speaker:has been recently
Speaker:expanded upon.
Speaker:This Barker
Speaker:hypothesis was
Speaker:around, I think
Speaker:the 60s or so,
Speaker:and he postulated
Speaker:the impact of a
Speaker:lifetime of
Speaker:exposures to a
Speaker:person's current
Speaker:state of health.
Speaker:And that was
Speaker:expanded upon in,
Speaker:I think it was in
Speaker:2000, or after
Speaker:2000 and late
Speaker:90s, in a new
Speaker:concept, which is
Speaker:again, just the
Speaker:evolution of the
Speaker:Barker hypothesis
Speaker:and the designs
Speaker:of health and
Speaker:disease
Speaker:hypothesis, which
Speaker:pretty much looks
Speaker:at the whole
Speaker:lifespan as to
Speaker:how certain
Speaker:factors may have
Speaker:influenced the
Speaker:person's current
Speaker:state of
Speaker:microbiome.
Speaker:And subsequently
Speaker:what impact that
Speaker:has on immunology
Speaker:and so on
Speaker:and so forth.
Speaker:So yes, but to
Speaker:answer your
Speaker:question, most
Speaker:certainly a
Speaker:compromise
Speaker:gastrointestinal
Speaker:tract.
Speaker:I mean, it's the
Speaker:point of entry
Speaker:that we have,
Speaker:it's the most
Speaker:dramatic point of
Speaker:entry in terms of
Speaker:a perceptive
Speaker:entry that we
Speaker:have to the
Speaker:environment.
Speaker:So yeah, most
Speaker:certainly it can
Speaker:induce a
Speaker:CDR1 state.
Speaker:It's probably one
Speaker:of the greater
Speaker:means in
Speaker:which to do so.
Speaker:It's not
Speaker:the only.
Speaker:One of the other
Speaker:ways is actually
Speaker:by way of simple
Speaker:things, like
Speaker:those of you whom
Speaker:are tattooed, who
Speaker:have a lot of
Speaker:tattoos on
Speaker:the body.
Speaker:I love tattoos
Speaker:for the cosmetic
Speaker:reasons of them,
Speaker:but they're
Speaker:really not good
Speaker:for the
Speaker:immune system.
Speaker:They're really
Speaker:not good for the
Speaker:immune system
Speaker:because it
Speaker:creates a low
Speaker:grade perpetual
Speaker:immune activity
Speaker:based upon the
Speaker:lead that's in
Speaker:these tattoos.
Speaker:And even if you
Speaker:had lead free
Speaker:tattoos, there
Speaker:are other- I was
Speaker:about to ask.
Speaker:Yeah, there are
Speaker:other- 10
Speaker:minutes.
Speaker:Puts within them.
Speaker:They're less
Speaker:impactful, but
Speaker:they're still
Speaker:impactful to
Speaker:some degree.
Speaker:So those who have
Speaker:tattoos, you
Speaker:should always be
Speaker:using chlorella.
Speaker:I'm sorry, you
Speaker:gotta always use
Speaker:chlorella and
Speaker:find a way in
Speaker:which to preserve
Speaker:your iron.
Speaker:Because if you
Speaker:have a lot of
Speaker:tattoos and
Speaker:you're
Speaker:experiencing
Speaker:reoccurring
Speaker:anemia, it ties
Speaker:into what I
Speaker:mentioned to you
Speaker:before about this
Speaker:perpetual
Speaker:monocyte
Speaker:reactivation.
Speaker:That makes total
Speaker:sense as well.
Speaker:Rob, I would love
Speaker:to do a study.
Speaker:Maybe one of your
Speaker:audience can find
Speaker:a way in which we
Speaker:can actually do
Speaker:so efficiently,
Speaker:whereby we
Speaker:actually map the
Speaker:correlation
Speaker:between those
Speaker:whom have
Speaker:tattoos, as well
Speaker:as the extent or
Speaker:the timeframe of
Speaker:chronic viral
Speaker:expression,
Speaker:fatigue, chronic
Speaker:viral expression.
Speaker:And I'm sure, I
Speaker:hypothesize that
Speaker:there is an
Speaker:intimate,
Speaker:nobody's done the
Speaker:study, by
Speaker:the way.
Speaker:That's why I'm
Speaker:putting
Speaker:out there.
Speaker:No one's done the
Speaker:study yet.
Speaker:No one's done the
Speaker:study to see what
Speaker:tattoos, how
Speaker:tattoos increase
Speaker:the vulnerability
Speaker:for post-viral
Speaker:fatigue.
Speaker:No one's done the
Speaker:study yet.
Speaker:Yeah, no, I don't
Speaker:think anyone's
Speaker:ever thought of
Speaker:doing that study.
Speaker:It's definitely novel.
Speaker:I mean, maybe we
Speaker:would have to get
Speaker:this in front of
Speaker:Ben Greenfield,
Speaker:because he's
Speaker:definitely
Speaker:well-to-do and
Speaker:fairly inked up.
Speaker:So maybe he's
Speaker:someone to sort
Speaker:of talk to.
Speaker:You've really
Speaker:alluded to this,
Speaker:Justin, but I
Speaker:think it's a
Speaker:great place to
Speaker:start ending off.
Speaker:But just this
Speaker:idea of the
Speaker:central nervous
Speaker:system and its
Speaker:role in
Speaker:triggering this
Speaker:sort of
Speaker:immunological
Speaker:metabolic
Speaker:dysfunction.
Speaker:Again, me just
Speaker:taking a sort of
Speaker:a very layman's
Speaker:approach to it,
Speaker:but the idea that
Speaker:when the nervous
Speaker:system, when the
Speaker:body is stressed,
Speaker:it's not going to
Speaker:sort of really,
Speaker:it doesn't, okay,
Speaker:it does to an
Speaker:extent, but with
Speaker:stress is
Speaker:perceived
Speaker:as stress.
Speaker:It doesn't matter
Speaker:if it's
Speaker:psychological,
Speaker:broadly speaking,
Speaker:or physiological.
Speaker:You're going to
Speaker:have the sort of
Speaker:the same
Speaker:biological
Speaker:reactions.
Speaker:There's going to
Speaker:be a surge in
Speaker:catecholamines, a
Speaker:surge in
Speaker:hormones.
Speaker:That's going to
Speaker:increase the
Speaker:transcription
Speaker:factors.
Speaker:And then you're
Speaker:going to have
Speaker:this downstream
Speaker:effect again on
Speaker:the immune system
Speaker:and subsequently
Speaker:on the metabolism
Speaker:once again.
Speaker:And we're going
Speaker:to end up in this
Speaker:state of being in
Speaker:CDR1 two or
Speaker:three, which I'm
Speaker:not sure, but I'm
Speaker:sure you can sort
Speaker:of elucidate that
Speaker:more succinctly
Speaker:than I can.
Speaker:Do you think that
Speaker:this theory of,
Speaker:and I suppose it
Speaker:ties into some of
Speaker:Leo Primbok's
Speaker:work, the
Speaker:psychoneuroimmunology,
Speaker:do you think
Speaker:there is merit to
Speaker:this idea that a
Speaker:sort of
Speaker:psychological
Speaker:stress in general
Speaker:can drive this
Speaker:metabolic
Speaker:dysfunction?
Speaker:Or is that sort
Speaker:of more of an
Speaker:edge case?
Speaker:An edge case?
Speaker:Good question.
Speaker:I think again, it
Speaker:is dependent upon
Speaker:the individual as
Speaker:to what the
Speaker:individual had
Speaker:been exposed to
Speaker:over a course of
Speaker:a lifespan.
Speaker:As an example,
Speaker:you know, on a
Speaker:swash leg, I'm
Speaker:going to use him
Speaker:as an example,
Speaker:and he even
Speaker:discusses this in
Speaker:a couple of his
Speaker:documentaries,
Speaker:whereby his, him
Speaker:and his brother
Speaker:were exposed to an
Speaker:abusive father.
Speaker:His brother ended
Speaker:up killing
Speaker:himself in a car
Speaker:crash because
Speaker:whilst he was
Speaker:drunk, whilst he
Speaker:was intoxicated.
Speaker:So, you know, in
Speaker:two
Speaker:circumstances,
Speaker:you have one
Speaker:person utilizing
Speaker:that stress for
Speaker:improvement upon
Speaker:what adaptability
Speaker:to some degree,
Speaker:based upon the
Speaker:circumstances
Speaker:he was in.
Speaker:And the other,
Speaker:where that stress
Speaker:overwhelmed him
Speaker:to the point
Speaker:where he
Speaker:pretty much
Speaker:equated to the
Speaker:state of
Speaker:destruction.
Speaker:So it really,
Speaker:it's not even a
Speaker:question of just
Speaker:genetic.
Speaker:I mean, for sure,
Speaker:genetics do play
Speaker:a role in one's
Speaker:stress tolerance.
Speaker:However, what
Speaker:micron RNA is
Speaker:being expressed
Speaker:to put upon
Speaker:certain sequences
Speaker:of one's life
Speaker:experiences will
Speaker:have also a
Speaker:greater
Speaker:determining
Speaker:epigenetic effect
Speaker:than just that of
Speaker:DNA alone.
Speaker:So yes, is stress
Speaker:a psychological
Speaker:stress
Speaker:contributor
Speaker:for sure.
Speaker:But what does
Speaker:that mean?
Speaker:I think that's
Speaker:the question that
Speaker:you're asking.
Speaker:What does that
Speaker:really mean?
Speaker:Like, how can we
Speaker:quantify this?
Speaker:And the truth is,
Speaker:from an
Speaker:evidence-based
Speaker:paradigm, you
Speaker:can't, you can't,
Speaker:because then
Speaker:you've got to
Speaker:bring it into
Speaker:reductive models
Speaker:and create the
Speaker:ducted reasoning,
Speaker:which doesn't
Speaker:take into account
Speaker:every possible
Speaker:life experience
Speaker:that the
Speaker:individual
Speaker:has had.
Speaker:Now, I don't know
Speaker:two people, even
Speaker:twins, that have
Speaker:had the exact
Speaker:identical life
Speaker:experiences, or
Speaker:at least have not
Speaker:perceived the
Speaker:exact life
Speaker:experiences
Speaker:the same.
Speaker:I think every
Speaker:individual,
Speaker:albeit those who
Speaker:might be a twin
Speaker:or not,
Speaker:experience a life
Speaker:and a individual
Speaker:from an
Speaker:individual
Speaker:perspective.
Speaker:So what
Speaker:does that mean?
Speaker:And now we are
Speaker:venturing into
Speaker:the realm of
Speaker:metaphysics
Speaker:again, like what
Speaker:is consciousness?
Speaker:What is life?
Speaker:What does this
Speaker:all mean?
Speaker:And like, what do
Speaker:we mean in our
Speaker:experience?
Speaker:Not just what
Speaker:does that
Speaker:experience mean
Speaker:to us, what do we
Speaker:mean within the
Speaker:experience?
Speaker:Like, what is our
Speaker:essence in
Speaker:all this?
Speaker:And I think
Speaker:regardless of
Speaker:trying to, once
Speaker:again, put a
Speaker:remedy to a
Speaker:challenge or a scenario
Speaker:or to a category,
Speaker:considering
Speaker:compassionately
Speaker:the individual
Speaker:and as to what it
Speaker:is that they are
Speaker:reporting, they
Speaker:are going
Speaker:through, is
Speaker:incredibly
Speaker:important.
Speaker:Compassion and
Speaker:cooperation is
Speaker:the way, I would
Speaker:love to believe,
Speaker:is the way of the
Speaker:future of
Speaker:medicine.
Speaker:But in order for
Speaker:that to come into
Speaker:complete
Speaker:fruition, we need
Speaker:to change the way
Speaker:in which we
Speaker:perceive or how
Speaker:we perceive
Speaker:others, let alone
Speaker:how we perceive
Speaker:ourselves.
Speaker:I mean, we first
Speaker:can change how we
Speaker:perceive
Speaker:ourselves.
Speaker:That in its own
Speaker:right is a rite
Speaker:of passage, which
Speaker:I think takes
Speaker:multiple
Speaker:lifetimes to do,
Speaker:in all honesty,
Speaker:but there's no
Speaker:reason as to why
Speaker:we cannot
Speaker:simultaneously at
Speaker:least attempt and
Speaker:try to change our
Speaker:perception
Speaker:of others.
Speaker:And also again,
Speaker:just venturing
Speaker:into the
Speaker:metaphysics here,
Speaker:again, Professor
Speaker:Hugh Limb as a
Speaker:professor who was
Speaker:treating the
Speaker:medically, sorry,
Speaker:the criminally
Speaker:insane in Hawaii,
Speaker:and he adopted
Speaker:this Hawaiian
Speaker:prayer called
Speaker:"Upon O'Pono."
Speaker:And there's a lot
Speaker:of obviously
Speaker:rumor around what
Speaker:it had or had not
Speaker:done, but by his
Speaker:own account, he
Speaker:was able to heal
Speaker:the criminally
Speaker:insane by way of
Speaker:changing his
Speaker:perception
Speaker:through this
Speaker:prayer of what it
Speaker:is that he
Speaker:believed these
Speaker:people to be.
Speaker:And perhaps that
Speaker:also ventures
Speaker:into yet another
Speaker:question is that
Speaker:are those we deem
Speaker:to be faulty, are
Speaker:those who we deem
Speaker:to be faulty the
Speaker:construct of our
Speaker:ego, trying to
Speaker:have them fit
Speaker:into a narrative
Speaker:of our own
Speaker:design, or is the
Speaker:construct of our
Speaker:ego and the
Speaker:narrative of our
Speaker:own design the
Speaker:problem
Speaker:over here?
Speaker:And I'm inclined
Speaker:to believe that
Speaker:egoic and
Speaker:identity of which
Speaker:the majority of
Speaker:humanity has
Speaker:adopted over
Speaker:throughout its
Speaker:incarnation,
Speaker:really is at
Speaker:fault in that we
Speaker:have lost, and
Speaker:I'm hoping that
Speaker:we can reemerge
Speaker:the compassionate
Speaker:understanding of
Speaker:our fellow man
Speaker:and what they're
Speaker:going through.
Speaker:Because truly
Speaker:it's only through
Speaker:understanding
Speaker:that we can
Speaker:cultivate
Speaker:patience to see,
Speaker:okay, like the
Speaker:psychology, what
Speaker:this person is
Speaker:experiencing
Speaker:might be trivial
Speaker:to you or to me
Speaker:or to somebody
Speaker:else, but to that
Speaker:person it's
Speaker:detrimental,
Speaker:okay?
Speaker:It's relative.
Speaker:Yeah, exactly,
Speaker:it's relative,
Speaker:incredibly
Speaker:relative.
Speaker:And bringing it
Speaker:back to the
Speaker:theory of
Speaker:relativity here,
Speaker:(Laughs)
Speaker:and the
Speaker:perspective
Speaker:influence that
Speaker:that has on life
Speaker:and the speed of
Speaker:life and
Speaker:everything that
Speaker:that can have
Speaker:from a
Speaker:perspective of
Speaker:physics,
Speaker:biophysics
Speaker:in the body,
Speaker:relative
Speaker:perspective most
Speaker:certainly has an
Speaker:impact on
Speaker:biophysics,
Speaker:undoubtedly.
Speaker:And there are
Speaker:actually some
Speaker:documented
Speaker:studies of this
Speaker:matter as well.
Speaker:And there is the
Speaker:Institute of
Speaker:Noetic Sciences
Speaker:that was founded
Speaker:by an astronaut,
Speaker:his name is Dr.
Speaker:Edgar Mitchell,
Speaker:of which they
Speaker:actually mapped
Speaker:out
Speaker:scientifically
Speaker:the impact of
Speaker:relative
Speaker:consciousness to
Speaker:biophysics, the
Speaker:movement of
Speaker:particles in the
Speaker:body itself.
Speaker:So it's, yes, to
Speaker:answer your
Speaker:question, most
Speaker:certainly it can
Speaker:lead into a CDR1,
Speaker:but as to what
Speaker:measure that, as
Speaker:to what point
Speaker:within a measure
Speaker:it could induce
Speaker:that is variable
Speaker:to the
Speaker:individual.
Speaker:It is not a set
Speaker:standard, it's
Speaker:not a set
Speaker:universal
Speaker:standard that
Speaker:everybody would
Speaker:be
Speaker:susceptible to.
Speaker:There's a varying
Speaker:degree of
Speaker:susceptibility
Speaker:across the board.
Speaker:Yeah, it would
Speaker:probably require
Speaker:a bit more than
Speaker:sort of an HRV
Speaker:intervention, I'd
Speaker:imagine to sort
Speaker:of try and
Speaker:ascertain that
Speaker:level of data.
Speaker:Justin, I think,
Speaker:to be honest,
Speaker:we've been going
Speaker:on for nearly
Speaker:three hours.
Speaker:(Laughs) So what I'd love
Speaker:to- Are you
Speaker:kidding me?
Speaker:Wow, this is
Speaker:incredible,
Speaker:fantastic, good.
Speaker:It's been
Speaker:absolutely
Speaker:amazing,
Speaker:thank you.
Speaker:To end off with,
Speaker:I'd love to ask
Speaker:you a few rapid
Speaker:fire questions,
Speaker:and then, yeah,
Speaker:let's call it a
Speaker:day, and we can
Speaker:then point people
Speaker:to where they can
Speaker:find you.
Speaker:But to start off
Speaker:with, what do you
Speaker:think is the most
Speaker:underrated
Speaker:nutrient from an
Speaker:immunological
Speaker:health
Speaker:standpoint?
Speaker:Most underrated
Speaker:nutrient.
Speaker:I know we had
Speaker:discussed this
Speaker:briefly before,
Speaker:and I wrote
Speaker:garlic, but I'm
Speaker:not sure.
Speaker:It's a really
Speaker:difficult
Speaker:question
Speaker:to answer.
Speaker:Within the
Speaker:context of CDR1,
Speaker:or in the context
Speaker:of, in what
Speaker:context?
Speaker:Let me ask you
Speaker:that, let me ask
Speaker:your question to
Speaker:your question, in
Speaker:what context?
Speaker:Okay.
Speaker:Let's go with,
Speaker:yeah, let's go
Speaker:with CDR1.
Speaker:It's what we've
Speaker:discussed most
Speaker:today, I think,
Speaker:so it's probably
Speaker:most relevant.
Speaker:Contextual,
Speaker:because CDR1 has
Speaker:many contributory
Speaker:factors to it.
Speaker:So I'm gonna go
Speaker:through those
Speaker:factors, and then
Speaker:I'll give you
Speaker:some indication.
Speaker:So if it's a
Speaker:question of
Speaker:compromised
Speaker:histamine
Speaker:intolerance in
Speaker:terms of a
Speaker:dietary histamine
Speaker:intolerance,
Speaker:those whom are
Speaker:able to
Speaker:metabolize
Speaker:sulfur, onion, I
Speaker:mean, works
Speaker:incredibly well,
Speaker:has a natural
Speaker:source of
Speaker:kerstin, and
Speaker:kerstin is the
Speaker:molecule, the
Speaker:nutrient in
Speaker:question, that
Speaker:helps a lot with
Speaker:modulating the
Speaker:mast cells.
Speaker:If it's a
Speaker:question of
Speaker:estrogen
Speaker:dominance that
Speaker:might be fueling
Speaker:the histamine, or
Speaker:perpetuating the
Speaker:histamine
Speaker:response, then
Speaker:broccoli and
Speaker:subsequent indole
Speaker:methane also
Speaker:support the
Speaker:modulation to the
Speaker:CDR1 response.
Speaker:If it's a
Speaker:question of
Speaker:prostate gladdon
Speaker:imbalance, I'm
Speaker:not a big fan of
Speaker:fish roll, but I
Speaker:am a big fan of
Speaker:perzolving
Speaker:mediators.
Speaker:Perzolving
Speaker:mediators.
Speaker:Yeah, so that
Speaker:there is a great,
Speaker:if there's an
Speaker:imbalance of
Speaker:lipid utility,
Speaker:that would be a
Speaker:place to start.
Speaker:If there's
Speaker:imbalance of
Speaker:methylation
Speaker:imbalance, then
Speaker:determining
Speaker:exactly whether
Speaker:or not, if it's a
Speaker:beta oxidative
Speaker:issue, then
Speaker:pantothenin can
Speaker:work
Speaker:incredibly well.
Speaker:If it's a pyrol
Speaker:issue, then
Speaker:pyrolyloxin can
Speaker:work really well.
Speaker:If it is a
Speaker:question of poor
Speaker:glutathione
Speaker:recycling and
Speaker:your GSSG levels
Speaker:being higher,
Speaker:then rubber
Speaker:flabbing can work
Speaker:incredibly well.
Speaker:I think I gave
Speaker:enough examples.
Speaker:I think so.
Speaker:You answered that
Speaker:as only an
Speaker:academic could,
Speaker:is that already
Speaker:possible?
Speaker:Yeah, it's a
Speaker:broad question.
Speaker:It's like, you
Speaker:know, within,
Speaker:even in the
Speaker:subject of CDR1
Speaker:or TH2 dominance,
Speaker:what, you know,
Speaker:there's so many
Speaker:contradictory
Speaker:factors that can
Speaker:have an influence
Speaker:on that.
Speaker:Like, one can
Speaker:even venture into
Speaker:amino acids now,
Speaker:like theanine, to
Speaker:prove a polygonal
Speaker:response, and
Speaker:thereby hopefully
Speaker:mitigating
Speaker:glutamate
Speaker:dominance, which
Speaker:also by way,
Speaker:influences CDR1
Speaker:expression,
Speaker:glutamate
Speaker:dominance.
Speaker:So yeah, which, like
Speaker:polysaccharides
Speaker:have an influence
Speaker:on activating
Speaker:NMDA receptors,
Speaker:which are one of
Speaker:the subsets of,
Speaker:there's two
Speaker:classes of
Speaker:glutamate
Speaker:receptors.
Speaker:It's one of the
Speaker:subsets of the
Speaker:main class of
Speaker:glutamate
Speaker:receptors.
Speaker:So, you know,
Speaker:theanine, green
Speaker:tea, could have
Speaker:sort of
Speaker:contextual
Speaker:importance
Speaker:as well.
Speaker:That's
Speaker:incredible,
Speaker:thank you.
Speaker:Okay, next one.
Speaker:What's one
Speaker:supplement you
Speaker:personally could
Speaker:not go without?
Speaker:Again, another
Speaker:contextual
Speaker:question.
Speaker:Can I not go
Speaker:within which,
Speaker:within which
Speaker:scenario?
Speaker:Just generally,
Speaker:if you got stuck
Speaker:in a desert
Speaker:island with one
Speaker:bottle of
Speaker:something.
Speaker:Yeah, my friend
Speaker:Dominic
Speaker:Nischwitz, he
Speaker:told me to say
Speaker:chlorella.
Speaker:(Laughing)
Speaker:I'm sorry for it.
Speaker:Chlorella,
Speaker:chlorella.
Speaker:Which is right, I
Speaker:think chlorella
Speaker:is incredible
Speaker:compound.
Speaker:Amazing, so many,
Speaker:it's got a great
Speaker:source of iodine,
Speaker:great binder,
Speaker:great B vitamin
Speaker:profile, great
Speaker:selenium profile,
Speaker:really is a
Speaker:super sweet.
Speaker:Supplement, could
Speaker:I not go without?
Speaker:You've got
Speaker:phosphatidylcholine
Speaker:here, I
Speaker:think, PC.
Speaker:Yeah, I think in
Speaker:my particular
Speaker:case, having
Speaker:historically
Speaker:having had issues
Speaker:with bioacid
Speaker:activity,
Speaker:and also
Speaker:subsequent
Speaker:certain cognitive
Speaker:memory recall
Speaker:issues, certain
Speaker:points when I had
Speaker:my water
Speaker:immunity,
Speaker:phosphatidylcholine
Speaker:was certainly
Speaker:mitigated a lot
Speaker:of this.
Speaker:So
Speaker:phosphatidylcholine
Speaker:is different, be
Speaker:on the top
Speaker:of the list.
Speaker:And I also do
Speaker:have certain PEMT
Speaker:genome that makes
Speaker:me more
Speaker:vulnerable to
Speaker:deficiency of
Speaker:cholera,
Speaker:phosphatidylcholine.
Speaker:So let's go with
Speaker:that one, let's
Speaker:go with that one.
Speaker:Okay, perfect.
Speaker:Emerging therapies you're
Speaker:most excited
Speaker:about or therapy?
Speaker:I always forget
Speaker:how, because I
Speaker:always wanted to
Speaker:say
Speaker:ionotrophysis,
Speaker:but it's not how
Speaker:you, it's
Speaker:ionophoresis.
Speaker:That was Newton,
Speaker:I must admit.
Speaker:Yeah, it's quite
Speaker:an interesting
Speaker:technology,
Speaker:almost works like
Speaker:on a battery type
Speaker:of a dark man
Speaker:concept in terms
Speaker:of the positive
Speaker:and
Speaker:negative charge.
Speaker:And what it does
Speaker:by inducing this
Speaker:ionic
Speaker:displacement, it
Speaker:opens up the
Speaker:membranes to be
Speaker:more accepting of
Speaker:nutrient
Speaker:delivery.
Speaker:So it's quite an
Speaker:interesting
Speaker:model.
Speaker:There's a few
Speaker:companies, Ion
Speaker:Layer, and there
Speaker:are others as
Speaker:well, that
Speaker:provide this
Speaker:technology by way
Speaker:of delivering NAD
Speaker:and glutathione.
Speaker:Molecules that
Speaker:are highly
Speaker:susceptible to
Speaker:the gastric
Speaker:environment as an
Speaker:example.
Speaker:So it's quite
Speaker:cool, I'm working
Speaker:with a scientist,
Speaker:his name's also
Speaker:Justin, Justin
Speaker:Kirkland,
Speaker:incredible mind.
Speaker:He's got some
Speaker:real cool
Speaker:innovative
Speaker:technologies that
Speaker:he's busy with at
Speaker:the moment.
Speaker:And I'm hopeful
Speaker:that in due
Speaker:course, majority
Speaker:of the nutrients
Speaker:that we prescribe
Speaker:within our
Speaker:practice can
Speaker:actually be given
Speaker:by way of patch
Speaker:delivery rather
Speaker:than
Speaker:ingesting it.
Speaker:Obviously, albeit
Speaker:things like
Speaker:lipids, I think
Speaker:it would be more
Speaker:difficult to do.
Speaker:And the larger
Speaker:particles might
Speaker:be a little bit
Speaker:more challenging.
Speaker:Binders, we're
Speaker:certainly gonna
Speaker:wanna ingest for
Speaker:the purpose of
Speaker:the need to
Speaker:buy toxins.
Speaker:But yeah, I think
Speaker:it's an
Speaker:interesting tech
Speaker:because it does
Speaker:pave the way and
Speaker:the potential for
Speaker:not to have to
Speaker:consume so many
Speaker:pills, so many
Speaker:capsules and
Speaker:supplements,
Speaker:whilst still
Speaker:getting the
Speaker:benefit in the
Speaker:increase of
Speaker:biological
Speaker:availability.
Speaker:Yeah, no, that's
Speaker:an interesting
Speaker:one and one I'll
Speaker:definitely be
Speaker:exploring.
Speaker:Okay, let's end
Speaker:off with one
Speaker:about the gut.
Speaker:What's the
Speaker:biggest myth
Speaker:about gut health
Speaker:that you
Speaker:regularly
Speaker:encounter?
Speaker:It must be, it
Speaker:must certainly
Speaker:must have to do
Speaker:with fermented
Speaker:fruits,
Speaker:fermented fruits.
Speaker:People have this
Speaker:being told, I
Speaker:mean, it's only
Speaker:natural.
Speaker:Every time you,
Speaker:well, when you
Speaker:used to look at
Speaker:least in social
Speaker:media, it was all
Speaker:about kimchi and
Speaker:sauerkrauts and
Speaker:kefir and
Speaker:everything else.
Speaker:Now I'm not
Speaker:saying these are
Speaker:bad, they come
Speaker:textual again.
Speaker:But particularly
Speaker:in a TH2 dominant
Speaker:state, you do not
Speaker:wanna be
Speaker:consuming a lot
Speaker:of these foods
Speaker:because by nature
Speaker:of them being
Speaker:fermented,
Speaker:they're gonna
Speaker:have a high
Speaker:histamine blow.
Speaker:Okay, so it's
Speaker:really like, it's
Speaker:such a myth like,
Speaker:eat more
Speaker:sauerkraut and
Speaker:you're gonna have
Speaker:healthy
Speaker:microbiome or
Speaker:drink more kefir
Speaker:and you're gonna
Speaker:have healthy
Speaker:microbiome.
Speaker:Or if you have
Speaker:stomach issues,
Speaker:please drink
Speaker:more kefir.
Speaker:No, like if you
Speaker:have stomach
Speaker:issues that it's
Speaker:been instigated
Speaker:by muscle
Speaker:activation
Speaker:syndrome, please
Speaker:do not drink more
Speaker:fucking kefir.
Speaker:Flipping,
Speaker:flipping,
Speaker:kefir, kanao.
Speaker:Like this, yeah,
Speaker:just a context, a
Speaker:context, content
Speaker:and context.
Speaker:Yeah, Justin,
Speaker:those are perfect
Speaker:answers.
Speaker:Thank you again.
Speaker:Answered only as
Speaker:an
Speaker:academic could.
Speaker:I've said this
Speaker:once before, that
Speaker:was to Tyler
Speaker:Pansner, but I
Speaker:think I might be
Speaker:in love with
Speaker:your brain.
Speaker:I really can't
Speaker:thank you enough
Speaker:for your time.
Speaker:You've already
Speaker:alluded to
Speaker:autonomic
Speaker:coaching, but
Speaker:where can people
Speaker:find you if
Speaker:they'd like to
Speaker:connect?
Speaker:autonomic_coaching
Speaker:through our
Speaker:website,
Speaker:www.autonomiccoaching.com.
Speaker:Else you can drop
Speaker:us an email, info
Speaker:at
Speaker:autonomiccoaching.com.
Speaker:Do keep an eye
Speaker:out for my book
Speaker:that is gonna be
Speaker:provisionally
Speaker:going to be
Speaker:launched at the
Speaker:end of September.
Speaker:And within that,
Speaker:there'll be even
Speaker:more details as
Speaker:to how you can
Speaker:connect with us.
Speaker:That's perfect,
Speaker:and we'll be
Speaker:short-linked to
Speaker:all of that in
Speaker:the show notes.
Speaker:Justin, thank you
Speaker:so much for
Speaker:your time.
Speaker:Thank you, Rob.
Speaker:Take care.