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Welcome to the VP

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Live podcast, the

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show where we

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bring you

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actionable health

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advice for

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revealing minds.

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I'm your

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host, Rob.

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My guest today is

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Justin McGuire, a

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South

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African-based

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holistic health

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and performance

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coach who works

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with clients to

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help them

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optimize all

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aspects of their

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health and lives.

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Today's

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conversation

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centers around

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how the immune

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system ultimately

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governs

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metabolism.

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And while we

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certainly get

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into the weeds

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today, I really

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encourage you to

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listen through,

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as the

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information

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Justin provides

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is nothing short

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of pure gold.

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Expect to learn

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how the immune

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system actually

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operates, why

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chronic

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inflammation

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might actually be

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the cause of

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weight gain in so

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many populations,

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and Justin's top

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picks for

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nutrients that

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help to improve

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immune system

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function.

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Now, on to the

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conversation with

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Justin McGuire.

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Hey, Justin,

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thanks for

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being here.

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We've rubbed

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shoulders over

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the years, but

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we've never

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really sat down

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to have a

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conversation

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as such.

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So I'm excited to

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have this

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opportunity to

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pick your brain

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on this topic,

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which is

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something I'm

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becoming more and

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more passionate

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about by the day.

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And that's this

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concept of

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immunomatabolism.

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The idea, loosely

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speaking, that

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the metabolism is

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mediated, to some

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degree, by the

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immune system and

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vice versa.

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And again, just

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the idea that

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subsequently a

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lot of disease

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can be viewed

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through this lens

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and potentially

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solved through

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this lens

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as well.

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I know for the

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listeners that

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that probably

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sounds pretty

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convoluted, but I

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promise we'll

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break it down

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shortly.

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First, though,

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I'd love to learn

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a little more

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about you.

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I know through

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something of your

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story, through

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our mutual friend

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Ben Law, that

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beyond that, I'm

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ashamed to say I

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don't actually

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know too much

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about your

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backstory, but

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I'd love to

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understand a bit

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more about how

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you ended up in

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this sort of

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integrative

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health and

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performance

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space.

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It's good

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to be here.

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Thank you, Rob.

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Looking forward

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to sharing some

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insight.

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So my story is an

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interesting one.

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I just actually

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had a

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conversation with

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one of my

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metaphysicians.

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And yes, I'm

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probably the most

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hippie scientist

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you're ever going

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to come across.

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And in our

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conversation this

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morning, it was

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the fact that

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I've literally

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gone through four

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major personas

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just during this

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one single

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lifetime itself.

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So my previous

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persona narrative

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was very

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different as

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opposed to whom I

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am now today.

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And I think this

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can, many people,

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not many, but

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some may attest

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to having

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experienced the

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contrast of self.

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So my former life

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in my 20s and my

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teens, I was

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competitive in

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the fitness world

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and bodybuilding

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and martial arts

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and so on.

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I was a personal

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trainer.

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And it served

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purpose

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for a while.

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However, it

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didn't provide me

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with the mental

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stimulus that I

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inherently was

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craving.

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Suffice to say,

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like a soul,

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well, again,

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maybe not like a

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soul, these

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definitive

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statements really

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get me sometimes.

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And the more

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conscious you

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become, the more

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aware you are of

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the words you

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choose to use.

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For some of us,

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we go through

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dark nights of

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assault, some of

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which are

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self-inflicted in

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terms of the

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sequence of

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events that

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lead to it.

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Others are

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inflicted

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upon us.

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But for whatever

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reason it is that

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we, or however it

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is that we end up

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there, we go

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through a moment

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of reflection.

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So that happened

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in my 30th and

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31st year,

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between the 30

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and the 31st year

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of my life.

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And then shortly

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thereafter,

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having gone

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through that very

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extreme moment in

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my life, of which

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the majority of

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it was actually

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impacted by my

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own poor

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decisions,

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admittedly.

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But not knowing

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as to, at that

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time in my life,

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not knowing as to

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why it is that I

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had a propensity

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to create, to

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have, to choose

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wrongly.

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And only later on

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that I started to

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discover that

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there were so

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many more layers

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into the

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complexity of

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life,

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particularly our

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lives, that can

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influence one's

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perception and

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thus one's own

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personal

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identity.

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And when we are

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in a state of

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water pilot, and

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particularly if

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we're not

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self-conscious,

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we're not

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conscious of

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self, not

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self-conscious,

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we're not

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conscious of

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self, it can lead

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us astray.

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So in any case, I

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would let myself

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astray based upon

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a whole lot of

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variables that

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are unnecessary

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to divulge into,

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because it's not

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about what led

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you there, it's

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the fact that it

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happened, and

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what are you

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gonna do

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about it?

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Where taking

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responsibility

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requires letting

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go of things that

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got you there,

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but taking full

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hold of what it

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is that you were,

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or what it is

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that you are, and

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wanting to

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change, unless

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you don't

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want to change.

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And if life is

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going the right

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direction, I want

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me to keep on

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doing what it is

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that you feel

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necessary, but

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mine wasn't.

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And I was

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confronted with

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an opportunity to

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either pass away,

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because

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literally, that's

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how thin my

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lifeline was, or

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to make a change.

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And I made a

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change, and

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subsequently

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making a change,

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and the universe

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really threw a

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spanner into the

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works and

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challenged me to

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yet

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another degree.

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And about 18

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months after I'd

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made a change,

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I went through a

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bit of a depth,

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an emotional

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depth that

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resulted in a...

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What happens when

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you've been

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sober, and then

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you slip up?

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Oh, come on, it's

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such a

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simple word.

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Uh, this is like

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the blind,

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in the blind.

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Relapse, relapse,

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relapse.

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Gosh, it's just

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the simplest

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words, right?

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It's just funny.

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So it resulted,

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this is what

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happens off the

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COVID, right?

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It's like all the

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complex words, no

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problem, but the

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simple things of

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joining krumjags

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is like really

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the word you

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wanna...

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And perhaps I've

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blocked it out of

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my psyche, to

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some

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extent, as well.

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Yeah, this is

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where you just

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eat all the urode

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monophosphate and

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just pray, yeah,

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and I can

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understand that.

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(Laughing) So anyway, it

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resulted in a

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relapse.

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And in that

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relapse, I had

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to, once again,

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revisit what it

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was that I had

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not been

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addressing.

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And I think as

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many men, from

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our generation at

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least, and

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generations

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prior, we were

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taught to pretty

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much suppress the

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expression of

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emotions and to

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just

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tough it out.

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Blood-swayed

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interiors is the

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motto of our

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generation.

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So yeah, with

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that, just the

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avoidance sets

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in, right?

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So you'll find

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elaborate ways to

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avoid what's

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actually going on

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within yourself,

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particularly by

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way of expression

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of ego, which

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didn't help much,

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I'm grateful for

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my body, which

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that's

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like I have.

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But in being able

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to build muscle

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quite quickly, I

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was able to build

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up a persona and

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ego to avoid a

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lot of things

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really

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easily as well.

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(Laughing) So, and see

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whether the

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relapse happened,

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came out of that,

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and things then

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really started to

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settle for me,

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like really

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started to shift.

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The foundation

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started to shift

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into a whole new

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dimension of

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self-experience.

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And then

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subsequently, I

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was doing really

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well, and then

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literally six

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months

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thereafter, yet

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another layer of

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complexity.

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The universe is

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like, okay, you

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ready for the

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next test?

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You ready for the

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next test?

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You ready for the

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next test?

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And then I

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developed

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Polymalgeoromatica.

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Now this is an

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autoimmune

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disease that

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mostly afflicts

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people over the

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age of 55.

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It's an extreme

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debilitating

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autoimmune

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condition, this

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chronic low grade

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inflammation that

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impacts not only

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pain in the body,

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but also causes a

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lot of

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neuroinflammatory

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outcomes and

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symptoms.

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So I went to

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every specialist,

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I mean, I spent

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money that I

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didn't have to

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try and get into

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the best

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specialist.

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And 12th of the

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best specialists

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in the country

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later, I was told

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it's all

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psychosomatic.

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Now, I mean, the

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intensity of the

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pain was so bad

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that I literally

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couldn't sleep

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for three or five

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days at a time.

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So it had three

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or five days of

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perpetual

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insomnia.

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Long story short,

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this sounds like

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a big dramatic

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narrative, and I

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would actually

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cut it short

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because it's not

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about that.

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It's about what

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it actually

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taught me.

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And what it

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taught me is

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that, no matter

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how good the

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intention of the

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person, because I

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don't believe any

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of these

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specialists, and

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this is where the

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polarity of

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fitness

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communities or

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biohacking

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communities or

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precision

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medicine or

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functional

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medicine

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communities can

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really lead

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people astray.

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Doctors are not

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at fault.

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I'm gonna make

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the statement

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right there.

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Doctors are not

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at fault.

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Like to get into

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medical school,

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do you know how

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much discipline

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and dedication it

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requires?

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Literally

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finishing it.

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It's not the

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intention of

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these individuals

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to not

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help people.

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It's actually the

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intention to be

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of service.

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It's the

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institution that

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is the problem.

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And the

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institution has

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led people astray

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into

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compartmentalizing

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their health.

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And because I

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wasn't able to be

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fit in, because

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they weren't able

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to fit me

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into a box.

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Paradigm, yeah.

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Into a paradigm,

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I became the

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psychosomatic

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patient.

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Despite all the

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symptoms that

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we're saying

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otherwise.

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Yes, most

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certainly there

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is some truth to

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that as well.

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I won't say that

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they were

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entirely wrong.

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There is most

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certainly some

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truth to it.

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But the truth

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came in that,

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yes, there were

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some psycho,

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there were many,

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not some, there

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were many

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psychological

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traumas that were

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coming up to the

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surface, which

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were expressing

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themselves

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on my body.

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I didn't know

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this at the time.

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I mean, this is

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like, you know, I

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was a bodybuilder

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two years prior

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to that.

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Competing, sorry,

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a year

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prior to that.

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I had done my

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last

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bodybuilding show.

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So I was in that

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whole fitness

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community, like,

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you know, Grant

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Go, Grant and Go,

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5am Club, you

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know, Hell's

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Bells, off

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your squat.

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So I don't really

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know like, you

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know, like the

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somatic impact

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that can happen

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from emotional

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response.

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I mean, I heard

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of it, but I kind

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of, to be honest

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with you, I

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thought it was a

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bit of a hogwash.

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I thought it was

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like, it's the

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things that

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esoteric believe

Speaker:

in kind of

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thing, right?

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But a little bit,

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I know how

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truthful that

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actually was.

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So much

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truth to it.

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So it went wrong

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that it was part,

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it had

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psychosomatic,

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there was certain

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elements of

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psychosomatic

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contribution

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toward my state.

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But this is where

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like, again, in

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the human

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dualistic

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perceptive

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paradigm, we

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separate things.

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We forget that

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there's actually

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continuity in

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everything.

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And this is where

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one of my

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favorite writings

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of all time, it's

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actually an

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essay, it's not a

Speaker:

book by Antoine

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Fabre de la Vie,

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and he wrote his

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essay in the

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late 1700s.

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And the essay is

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entitled, "The

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Metaphysical and

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Intellectual

Speaker:

Constitution

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of Man."

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Within this

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essay, he has a

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graphical

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depiction of the

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intersection.

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Within his

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semantics, he

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doesn't use mind,

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body and soul, he

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uses soul, spirit

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and body.

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But basically

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they depict what

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we understand to

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be mind, body and

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soul, and the

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difference of

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emotional

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intersect that

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can happen

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depending upon

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where we are in

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our state of

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consciousness,

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whether it is

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more so in the

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anima, the

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animus, or

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whether it's more

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in God

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consciousness and

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everything in

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between.

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So in looking at

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that model,

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knowing that

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whatever happens

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to the mind

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happens to the

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body, certainly,

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but whatever's

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happening to the

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body can

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perpetuate what's

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happening in the

Speaker:

mind as well.

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And this is one

Speaker:

of the first big

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pieces of the

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puzzle that came

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together.

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I had probably,

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I had done it on

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my own, because I

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didn't

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have any help.

Speaker:

I went to

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everybody and

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they put me on

Speaker:

pregnancy zone

Speaker:

and they put me

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on

Speaker:

anti-psychotics

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and everything

Speaker:

else, which just

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made me worse.

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Yeah, so as I was

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saying, so I

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didn't have

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pretty much any

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help from the

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specialists,

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although they had

Speaker:

good attention,

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they weren't able

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to fit me into a

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model, into

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like a mold.

Speaker:

So I had to

Speaker:

pretty much

Speaker:

figure myself

Speaker:

out, which was

Speaker:

quite

Speaker:

frustrating,

Speaker:

because you look

Speaker:

into my

Speaker:

historical

Speaker:

education behind

Speaker:

biochemistry,

Speaker:

which I had a

Speaker:

very basic

Speaker:

biochemical, I

Speaker:

mean, it was

Speaker:

self-taught in

Speaker:

the early part of

Speaker:

my, I later on

Speaker:

got degrees, in

Speaker:

my thirties

Speaker:

subsequently

Speaker:

after this, I got

Speaker:

foundation

Speaker:

degrees and then

Speaker:

I got a

Speaker:

bachelor's and so

Speaker:

on at Biochem.

Speaker:

But in my

Speaker:

twenties, it's

Speaker:

very basic.

Speaker:

And I thought I

Speaker:

had to basically

Speaker:

start my whole

Speaker:

journey in

Speaker:

front of it.

Speaker:

But anyway, long

Speaker:

story short, when

Speaker:

the student is

Speaker:

ready, the

Speaker:

teacher will

Speaker:

appear, and along

Speaker:

my journey, I

Speaker:

started to be, I

Speaker:

was introduced to

Speaker:

certain function

Speaker:

medicine doctors,

Speaker:

integrated

Speaker:

medicine doctors,

Speaker:

all of which

Speaker:

actually provided

Speaker:

educational

Speaker:

resources as

Speaker:

well, which I put

Speaker:

myself through,

Speaker:

when I had the

Speaker:

financial reasons

Speaker:

to do so, which

Speaker:

was quite tough.

Speaker:

I mean, as you

Speaker:

probably are

Speaker:

aware of, having

Speaker:

had long haul

Speaker:

COVID-19 for two

Speaker:

years, it's

Speaker:

really difficult

Speaker:

to manage earning

Speaker:

a living whilst

Speaker:

being chronically

Speaker:

fatigued, right?

Speaker:

And brain fog to

Speaker:

boot on top of

Speaker:

that, let alone

Speaker:

the physical pain

Speaker:

that can also

Speaker:

sporadically

Speaker:

creep in when

Speaker:

there's not

Speaker:

enough cortisol

Speaker:

to mitigate the

Speaker:

inflammation.

Speaker:

So I did what I

Speaker:

could, and it was

Speaker:

a journey.

Speaker:

It was probably

Speaker:

the best PhD I've

Speaker:

ever earned in

Speaker:

life going

Speaker:

through that

Speaker:

journey,

Speaker:

which birthed the

Speaker:

opportunity to

Speaker:

start autonomic

Speaker:

coaching.

Speaker:

And autonomic

Speaker:

coaching is a

Speaker:

conceptual birth

Speaker:

child of mine,

Speaker:

within which I

Speaker:

truly am trying

Speaker:

to continue to

Speaker:

expand a honest

Speaker:

interdisciplinary

Speaker:

approach.

Speaker:

Because again, I

Speaker:

just wanna

Speaker:

emphasize,

Speaker:

doctors are not

Speaker:

at fault.

Speaker:

You can't blame,

Speaker:

it's like putting

Speaker:

somebody in a

Speaker:

label and saying

Speaker:

because they put

Speaker:

11 years of their

Speaker:

life into

Speaker:

educating

Speaker:

themselves to do

Speaker:

a certain

Speaker:

discipline, now

Speaker:

they're evil.

Speaker:

Like where's the

Speaker:

logic of that?

Speaker:

They're

Speaker:

not at fault.

Speaker:

It's just that

Speaker:

there are many

Speaker:

other ways apart

Speaker:

from allopathy as

Speaker:

to how one can

Speaker:

approach

Speaker:

remedying for

Speaker:

health, okay?

Speaker:

And this is where

Speaker:

autonomic

Speaker:

coaching comes

Speaker:

in, and we

Speaker:

provide

Speaker:

allopathic

Speaker:

support, we

Speaker:

provide

Speaker:

naturopathic

Speaker:

support, we

Speaker:

provide

Speaker:

psychological

Speaker:

support, we

Speaker:

provide lifestyle

Speaker:

coaching as well.

Speaker:

So it's the whole

Speaker:

kitchen computer,

Speaker:

the whole

Speaker:

paradigm to

Speaker:

support the

Speaker:

individual.

Speaker:

This is where

Speaker:

inductive

Speaker:

reasoning is, we

Speaker:

are able to

Speaker:

enable inductive

Speaker:

reasoning within

Speaker:

this paradigm.

Speaker:

You know,

Speaker:

evidence-based

Speaker:

medicine is based

Speaker:

on the reductive

Speaker:

model so that one

Speaker:

can take

Speaker:

deductive

Speaker:

outcomes from it,

Speaker:

which is great

Speaker:

for the populace,

Speaker:

for the masses.

Speaker:

But there's a

Speaker:

shortfall within

Speaker:

the outliers of

Speaker:

those who don't

Speaker:

fit into

Speaker:

the mold.

Speaker:

And this is where

Speaker:

inductive

Speaker:

reasoning

Speaker:

comes in.

Speaker:

So most of the

Speaker:

people that come

Speaker:

to see us,

Speaker:

come to see us

Speaker:

after they've

Speaker:

been to many

Speaker:

different

Speaker:

practitioners,

Speaker:

alternative as

Speaker:

well as

Speaker:

conventional, and

Speaker:

they just haven't

Speaker:

gotten

Speaker:

the result.

Speaker:

That they, well,

Speaker:

they haven't been

Speaker:

given their

Speaker:

life back.

Speaker:

Do we help, are

Speaker:

we successful

Speaker:

with all of those

Speaker:

we help?

Speaker:

No, we're not,

Speaker:

but are we

Speaker:

successful with the

Speaker:

majority of them?

Speaker:

Yes, we are.

Speaker:

And those who

Speaker:

we're not

Speaker:

successful with,

Speaker:

we have got an

Speaker:

extensive network

Speaker:

that we are able

Speaker:

to get solutions

Speaker:

to people.

Speaker:

And this is, the

Speaker:

reason why I'm

Speaker:

also putting this

Speaker:

out there is to

Speaker:

not allude anyone

Speaker:

to the idea that

Speaker:

we are the

Speaker:

holy grail.

Speaker:

Okay, there is no

Speaker:

such thing.

Speaker:

If something

Speaker:

doesn't work with

Speaker:

a certain

Speaker:

specialist or a

Speaker:

certain thought

Speaker:

process, don't

Speaker:

give up.

Speaker:

That's the

Speaker:

message I'm

Speaker:

trying to

Speaker:

put out there.

Speaker:

If anybody is

Speaker:

growing through a

Speaker:

tough time and

Speaker:

they've tried

Speaker:

everything, which

Speaker:

is impossible, is

Speaker:

to try everything

Speaker:

you need multiple

Speaker:

lifetimes.

Speaker:

Okay,

Speaker:

don't give up.

Speaker:

Like, have faith

Speaker:

and truly like

Speaker:

the power of, I'm

Speaker:

not religious,

Speaker:

but I'm very

Speaker:

spiritual.

Speaker:

And whether you

Speaker:

are or you're

Speaker:

not, I think it's

Speaker:

irrelevant to the

Speaker:

question.

Speaker:

Sometimes this

Speaker:

process is a

Speaker:

process of

Speaker:

positive

Speaker:

introspection,

Speaker:

positive

Speaker:

psychology can

Speaker:

really shift the

Speaker:

narrative of

Speaker:

where it is that

Speaker:

you're willing to

Speaker:

invest your

Speaker:

energy into.

Speaker:

So yes, we

Speaker:

help most.

Speaker:

Do we help

Speaker:

everyone know?

Speaker:

But that doesn't

Speaker:

mean that there

Speaker:

isn't a solution

Speaker:

for everybody.

Speaker:

And I think as a

Speaker:

community of

Speaker:

professionals,

Speaker:

health

Speaker:

professionals,

Speaker:

we're making, as

Speaker:

we are coming

Speaker:

together more and

Speaker:

more so, like

Speaker:

every year I see

Speaker:

that there's

Speaker:

better

Speaker:

cooperation and

Speaker:

less competition

Speaker:

happening.

Speaker:

And the stronger

Speaker:

that we can

Speaker:

create

Speaker:

cooperation, the

Speaker:

more likely that

Speaker:

we can do away

Speaker:

with states such

Speaker:

as

Speaker:

neurodiversity,

Speaker:

or at least

Speaker:

reduce the degree

Speaker:

in the percentile

Speaker:

of those who are

Speaker:

neurodivergent in

Speaker:

the populace,

Speaker:

which is, I mean,

Speaker:

just that, that

Speaker:

label alone, that

Speaker:

category needs so

Speaker:

much new

Speaker:

care, right?

Speaker:

Because the

Speaker:

levels of autism

Speaker:

have rise, the

Speaker:

level of

Speaker:

depression

Speaker:

has rise.

Speaker:

You know, despite

Speaker:

the fact that

Speaker:

Western medical

Speaker:

technologies have

Speaker:

been approved

Speaker:

upon, we're still

Speaker:

having an influx

Speaker:

of these

Speaker:

particular

Speaker:

states, which

Speaker:

need not be if we

Speaker:

can come together

Speaker:

and unify our

Speaker:

skill sets within

Speaker:

a paradigm that's

Speaker:

truly holistic.

Speaker:

That's holistic.

Speaker:

You know, there's

Speaker:

that word thrown

Speaker:

around, way too

Speaker:

easily has been

Speaker:

thrown around for

Speaker:

decades, but what

Speaker:

does it

Speaker:

really mean?

Speaker:

You know, and

Speaker:

what I believe

Speaker:

means is simply

Speaker:

the embodiment of

Speaker:

cooperation

Speaker:

throughout

Speaker:

different

Speaker:

disciplines.

Speaker:

That's holistic.

Speaker:

It's not one

Speaker:

discipline,

Speaker:

during many

Speaker:

different things

Speaker:

in the body, is

Speaker:

many disciplines

Speaker:

supporting the

Speaker:

complexity

Speaker:

of the body.

Speaker:

So that's where I

Speaker:

came, and that's

Speaker:

where the

Speaker:

business is here.

Speaker:

(Laughing) That's

Speaker:

incredible.

Speaker:

And I think

Speaker:

you've already

Speaker:

answered most of

Speaker:

my follow-ups.

Speaker:

What I really

Speaker:

want to sort of

Speaker:

just jump back at

Speaker:

you on is just

Speaker:

sort of your

Speaker:

thoughts on the

Speaker:

education model,

Speaker:

because when it

Speaker:

comes to sort of

Speaker:

traditional

Speaker:

medicine, and I'm

Speaker:

definitely not

Speaker:

qualified or also

Speaker:

smart enough to

Speaker:

make a judgment

Speaker:

call on the way

Speaker:

medicines talk,

Speaker:

but I have a

Speaker:

feeling you are,

Speaker:

or at least you

Speaker:

have some

Speaker:

insights

Speaker:

into the system.

Speaker:

And the way I

Speaker:

view it is

Speaker:

exactly the way

Speaker:

you view it, to

Speaker:

an extent.

Speaker:

I think that

Speaker:

physicians have

Speaker:

the best

Speaker:

intentions at

Speaker:

heart, but they

Speaker:

put into this

Speaker:

mold, they put

Speaker:

this state of

Speaker:

having to

Speaker:

function based on

Speaker:

a set of

Speaker:

guidelines and a

Speaker:

set of

Speaker:

principles, and

Speaker:

that's

Speaker:

very myopic.

Speaker:

And it causes

Speaker:

this very sort of

Speaker:

siloed approach

Speaker:

to healthcare,

Speaker:

which just

Speaker:

doesn't work.

Speaker:

And I've said

Speaker:

this before on

Speaker:

the podcast, I'm

Speaker:

sure you've said

Speaker:

it before on

Speaker:

others, but I do

Speaker:

think it

Speaker:

needs to change.

Speaker:

If you were, this

Speaker:

is a bit of a hot

Speaker:

take, but if you

Speaker:

were sort of

Speaker:

given carte

Speaker:

blanche as to how

Speaker:

you would

Speaker:

potentially

Speaker:

re-engineer the

Speaker:

way medicines

Speaker:

talk, what would

Speaker:

you put more an

Speaker:

emphasis on,

Speaker:

excuse me?

Speaker:

What would you

Speaker:

sort of take an

Speaker:

emphasis off?

Speaker:

How would you

Speaker:

sort of, briefly,

Speaker:

because I mean,

Speaker:

this could take

Speaker:

us down to a

Speaker:

whole other

Speaker:

rabbit hole, but

Speaker:

how would you

Speaker:

sort of recreate

Speaker:

medicine to

Speaker:

become from a

Speaker:

model standpoint,

Speaker:

to be more

Speaker:

effective and to

Speaker:

help more people?

Speaker:

Move away from a

Speaker:

predominant

Speaker:

statistical

Speaker:

machine at the

Speaker:

ideology.

Speaker:

Evidence-based

Speaker:

medicine, now

Speaker:

we're talking

Speaker:

about

Speaker:

conventional

Speaker:

Western medicine.

Speaker:

We're not talking

Speaker:

about alternative

Speaker:

medicine, such as

Speaker:

Chinese medicine

Speaker:

and naturopathy

Speaker:

or homeopathy,

Speaker:

but we're talking

Speaker:

about Western

Speaker:

medicine, and it

Speaker:

really started

Speaker:

off really well.

Speaker:

And being the

Speaker:

known illusion,

Speaker:

pharmacology is

Speaker:

not the demon.

Speaker:

It's just a

Speaker:

prayer of use,

Speaker:

that's the

Speaker:

problem.

Speaker:

As an example, if

Speaker:

you wanted the

Speaker:

word to be given

Speaker:

in excess of

Speaker:

belladonna,

Speaker:

that's also not

Speaker:

gonna be to any

Speaker:

benefit of

Speaker:

continuity

Speaker:

of health.

Speaker:

So it really is

Speaker:

like you can't

Speaker:

shout, "Oh, it's

Speaker:

a big farmer that

Speaker:

wants to

Speaker:

kill us all."

Speaker:

Well, no, a big

Speaker:

farmer is only a

Speaker:

cooperation,

Speaker:

okay?

Speaker:

A cooperation, a

Speaker:

cooperation.

Speaker:

It's a

Speaker:

cooperation.

Speaker:

And in being a

Speaker:

cooperation, it

Speaker:

has its profit

Speaker:

margins that it

Speaker:

needs to attain,

Speaker:

like any other

Speaker:

business.

Speaker:

But it's not,

Speaker:

it's like saying

Speaker:

BMW is to blame

Speaker:

for the road

Speaker:

accidents,

Speaker:

right?

Speaker:

All the deaths on

Speaker:

the road.

Speaker:

No, no, and you

Speaker:

can say, well,

Speaker:

you know, they

Speaker:

market their

Speaker:

drugs and they

Speaker:

try to get, they

Speaker:

push the

Speaker:

likelihood of

Speaker:

sale onto doctors

Speaker:

and so on.

Speaker:

But what else are

Speaker:

they meant to do?

Speaker:

If they didn't do

Speaker:

that, those

Speaker:

medicines

Speaker:

wouldn't also

Speaker:

reach people that

Speaker:

actually

Speaker:

do need it.

Speaker:

And this is where

Speaker:

the discernment

Speaker:

and improvement

Speaker:

of the sermon is

Speaker:

required with the

Speaker:

end health

Speaker:

practitioner,

Speaker:

meaning the

Speaker:

doctor, the

Speaker:

GP, right?

Speaker:

Everybody goes

Speaker:

and sees.

Speaker:

But the way in

Speaker:

which,

Speaker:

particularly when

Speaker:

it comes to like

Speaker:

socialistic

Speaker:

countries like

Speaker:

England or like

Speaker:

France, where the

Speaker:

healthcare is

Speaker:

free, right?

Speaker:

It's very much a

Speaker:

conveyor

Speaker:

belt system.

Speaker:

I have a friend

Speaker:

of mine who's a

Speaker:

doctor based in

Speaker:

Germany and

Speaker:

before he went

Speaker:

into private

Speaker:

practice, he said

Speaker:

that he had to

Speaker:

see 2,000 people

Speaker:

a month in order

Speaker:

to make, I think

Speaker:

it was like 8,000

Speaker:

euro a month.

Speaker:

2,000 people to

Speaker:

make 8,000

Speaker:

euro a month.

Speaker:

So it's like 10,

Speaker:

15 minutes, five

Speaker:

sometimes minute

Speaker:

consultations and

Speaker:

it's just in and

Speaker:

out, in and out.

Speaker:

So what are you

Speaker:

gonna do?

Speaker:

Like, I can't do

Speaker:

anything in 10

Speaker:

minutes.

Speaker:

Like I can have a

Speaker:

conversation with

Speaker:

somebody, but,

Speaker:

and if I look at

Speaker:

a lab report, I'm

Speaker:

probably gonna

Speaker:

look at like, you

Speaker:

know, single

Speaker:

markers and see

Speaker:

if there's

Speaker:

anything that

Speaker:

really

Speaker:

stands out.

Speaker:

I'm not gonna

Speaker:

have time to look

Speaker:

at correlation or

Speaker:

create a

Speaker:

correlation

Speaker:

analysis

Speaker:

by it all.

Speaker:

No way, because

Speaker:

there's no time.

Speaker:

And that design

Speaker:

at least, there

Speaker:

isn't any time.

Speaker:

So I think the

Speaker:

way in which to

Speaker:

nonetheless

Speaker:

support

Speaker:

organizational

Speaker:

construct in

Speaker:

terms of

Speaker:

financial

Speaker:

resources,

Speaker:

because we also

Speaker:

have to think

Speaker:

here, it's not

Speaker:

just about giving

Speaker:

everybody the

Speaker:

equal opportunity

Speaker:

of health.

Speaker:

That's a great, I

Speaker:

mean, that's a

Speaker:

wonderful,

Speaker:

wonderful

Speaker:

sentiment and

Speaker:

idea, but the

Speaker:

reality is in

Speaker:

order to do that,

Speaker:

we also have to

Speaker:

consider the

Speaker:

economics

Speaker:

of it all.

Speaker:

Okay, and the

Speaker:

economics of it

Speaker:

all mean that we

Speaker:

need to create

Speaker:

organizational

Speaker:

structures that

Speaker:

can provide a

Speaker:

personalized

Speaker:

service to some

Speaker:

degree, to a

Speaker:

greater degree

Speaker:

than is what

Speaker:

currently given,

Speaker:

but at the same

Speaker:

time, not

Speaker:

overburden the

Speaker:

financial

Speaker:

constraints of

Speaker:

these

Speaker:

organizations

Speaker:

that have been

Speaker:

set up by

Speaker:

different

Speaker:

governmental

Speaker:

organizations

Speaker:

across the world.

Speaker:

And I think the

Speaker:

way in which you

Speaker:

can do this is

Speaker:

by, biohacking is

Speaker:

most certainly,

Speaker:

it's not the

Speaker:

foolproof

Speaker:

structure, but it

Speaker:

definitely has

Speaker:

increased

Speaker:

consciousness

Speaker:

around wellness

Speaker:

for many

Speaker:

a people.

Speaker:

And one can also

Speaker:

argue that there

Speaker:

are gonna be

Speaker:

goods and bads to

Speaker:

everything, okay?

Speaker:

But however, if

Speaker:

we just take the

Speaker:

average, what

Speaker:

happens when the

Speaker:

person involved,

Speaker:

it gets involved

Speaker:

in a greater

Speaker:

state of

Speaker:

awareness of

Speaker:

what's going on

Speaker:

within

Speaker:

themselves, they

Speaker:

start to read

Speaker:

articles.

Speaker:

They start to

Speaker:

watch

Speaker:

YouTube videos.

Speaker:

They start to

Speaker:

engage with what

Speaker:

it is that's

Speaker:

actually going on

Speaker:

within

Speaker:

themselves.

Speaker:

Now, if we can

Speaker:

somewhat merge

Speaker:

that community

Speaker:

element, such as

Speaker:

what's happening

Speaker:

in biohacking

Speaker:

into a greater

Speaker:

community,

Speaker:

thereby not

Speaker:

creating the

Speaker:

necessity of

Speaker:

tribal mentality,

Speaker:

but doing away

Speaker:

with that tribal

Speaker:

mentality, but

Speaker:

still keeping the

Speaker:

underlying

Speaker:

positive premise

Speaker:

of it all, then

Speaker:

you can have one

Speaker:

doctor, for

Speaker:

example,

Speaker:

that has,

Speaker:

you know, somehow

Speaker:

a doctor manages

Speaker:

a particular

Speaker:

county in

Speaker:

England,

Speaker:

or say a

Speaker:

particular

Speaker:

village, not a

Speaker:

county, but a

Speaker:

particular

Speaker:

village in

Speaker:

England.

Speaker:

That doctor in

Speaker:

the current

Speaker:

construct of how

Speaker:

the NHS is set

Speaker:

up, patient eats

Speaker:

a book, comes and

Speaker:

sees a doctor on

Speaker:

a one-to-one.

Speaker:

But a one-to-one

Speaker:

is 10

Speaker:

minutes long.

Speaker:

But it doesn't,

Speaker:

you can't get

Speaker:

anywhere

Speaker:

with that.

Speaker:

So what about,

Speaker:

instead of having

Speaker:

this design,

Speaker:

you're having

Speaker:

single

Speaker:

consultation, you

Speaker:

have a group

Speaker:

model whereby the

Speaker:

doctor becomes

Speaker:

more proactively

Speaker:

involved in the

Speaker:

ongoing health of

Speaker:

the community,

Speaker:

right?

Speaker:

It sets certain

Speaker:

objectives, sets

Speaker:

certain

Speaker:

incentives for

Speaker:

the community to

Speaker:

elevate their

Speaker:

health together.

Speaker:

The biggest issue

Speaker:

that I see in

Speaker:

modern-day

Speaker:

psychological

Speaker:

health, at least,

Speaker:

is the separation

Speaker:

from man, from

Speaker:

man's self, is

Speaker:

isolation.

Speaker:

We live in a

Speaker:

world that's more

Speaker:

populated now

Speaker:

than ever before,

Speaker:

yet we are more

Speaker:

lonely than

Speaker:

ever before.

Speaker:

And that, just by

Speaker:

that on its own,

Speaker:

births many, many

Speaker:

a disease.

Speaker:

Okay, we're

Speaker:

beings, we're a

Speaker:

species that

Speaker:

needs embrace.

Speaker:

Okay, we're not

Speaker:

learned

Speaker:

creatures.

Speaker:

No matter what

Speaker:

anybody says,

Speaker:

this warrior

Speaker:

mentality, and go

Speaker:

sit on top of a

Speaker:

mountain and

Speaker:

meditate for

Speaker:

weeks or months

Speaker:

or years on end,

Speaker:

there may be,

Speaker:

there are a few

Speaker:

that have done

Speaker:

it, they can do

Speaker:

it, but whether

Speaker:

or not it's

Speaker:

healthy for a

Speaker:

person or not,

Speaker:

that's up

Speaker:

for debate.

Speaker:

And I don't

Speaker:

think,

Speaker:

personally, and

Speaker:

again, I'm not

Speaker:

omnipotent or

Speaker:

omnipresent

Speaker:

whatsoever, thank

Speaker:

God for that,

Speaker:

excuse the irony,

Speaker:

of what I just

Speaker:

said, but I do

Speaker:

believe that

Speaker:

humanity needs

Speaker:

more compassion,

Speaker:

and the only way

Speaker:

in which we can

Speaker:

improve upon the

Speaker:

medical system is

Speaker:

by implementing

Speaker:

consideration for

Speaker:

others in a

Speaker:

community

Speaker:

construct, really

Speaker:

bring the

Speaker:

community back

Speaker:

together.

Speaker:

So when something

Speaker:

happens, it's not

Speaker:

left to the nth

Speaker:

degree when

Speaker:

somebody's

Speaker:

completely

Speaker:

derailed, and

Speaker:

then they're

Speaker:

trying to have a

Speaker:

10 minute

Speaker:

consultation with

Speaker:

the doctor

Speaker:

to fix that.

Speaker:

Because this

Speaker:

faces it, things

Speaker:

don't just happen

Speaker:

overnight, unless

Speaker:

you catch like

Speaker:

typhoid fever,

Speaker:

by the way, most

Speaker:

deaths actually

Speaker:

occur from

Speaker:

non-communicable

Speaker:

diseases,

Speaker:

non-communicable

Speaker:

diseases.

Speaker:

78%, I think it

Speaker:

was in 86, I

Speaker:

can't remember,

Speaker:

but it's between

Speaker:

78 or 86, that

Speaker:

was the number

Speaker:

that I last saw

Speaker:

on the steps of

Speaker:

global

Speaker:

deaths, right?

Speaker:

Non-communicable

Speaker:

diseases is

Speaker:

responsible for

Speaker:

the majority of

Speaker:

deaths worldwide.

Speaker:

And by that you

Speaker:

mean things like

Speaker:

AOCVD, heart

Speaker:

disease, cancer,

Speaker:

et cetera.

Speaker:

Yeah, any disease

Speaker:

that's not caused

Speaker:

directly by a

Speaker:

pathogen assault.

Speaker:

Yeah.

Speaker:

So, methylene

Speaker:

blue, recovering

Speaker:

from COVID.

Speaker:

Not to be used

Speaker:

perpetually, but

Speaker:

the use of sort

Speaker:

of circumstances,

Speaker:

we had a

Speaker:

conversation

Speaker:

about this in the

Speaker:

second, as well.

Speaker:

We didn't need--

Speaker:

So things like

Speaker:

this, like you

Speaker:

know, certain

Speaker:

remedies, like

Speaker:

methylene blue,

Speaker:

that can be

Speaker:

destructive,

Speaker:

it most certainly

Speaker:

can cause harm if

Speaker:

it's used in the

Speaker:

wrong construct,

Speaker:

right?

Speaker:

But it most

Speaker:

certainly can

Speaker:

alleviate harm if

Speaker:

it's used in the

Speaker:

right construct.

Speaker:

But how do people

Speaker:

know this?

Speaker:

Like, I mean,

Speaker:

I've got degrees

Speaker:

in

Speaker:

biochemistry, right?

Speaker:

I've got degrees

Speaker:

in nutritional

Speaker:

science, but not

Speaker:

everybody has a

Speaker:

degree in

Speaker:

biochemistry and

Speaker:

nutritional

Speaker:

science, so now,

Speaker:

you know, you've

Speaker:

got the media

Speaker:

mention about its

Speaker:

potential

Speaker:

benefit, and

Speaker:

there are

Speaker:

incredible

Speaker:

benefits behind

Speaker:

this molecule.

Speaker:

It truly is a

Speaker:

molecule.

Speaker:

But we need more

Speaker:

of a community

Speaker:

for people to be

Speaker:

able to use these

Speaker:

remedies that

Speaker:

don't require a

Speaker:

script

Speaker:

successfully,

Speaker:

rather than use

Speaker:

it and feel

Speaker:

like crap.

Speaker:

Feel worse often

Speaker:

than they did

Speaker:

prior to

Speaker:

using it.

Speaker:

And this requires

Speaker:

more of a

Speaker:

community aspect.

Speaker:

And I think this

Speaker:

is the only way

Speaker:

in which we'll be

Speaker:

able to change

Speaker:

the trajectory of

Speaker:

modern-day

Speaker:

medicine.

Speaker:

When it comes to

Speaker:

like the

Speaker:

educational

Speaker:

component of it,

Speaker:

which is another

Speaker:

part of the

Speaker:

question

Speaker:

that you asked,

Speaker:

I think medical

Speaker:

school starts off

Speaker:

very well, but it

Speaker:

ends terribly.

Speaker:

(Laughs)

Speaker:

Sort of, yeah,

Speaker:

you sort of have

Speaker:

this sort of,

Speaker:

this base of

Speaker:

biochemistry or

Speaker:

physiology, and

Speaker:

then you slowly

Speaker:

sort of become a

Speaker:

trained

Speaker:

pharmacologist

Speaker:

where you start

Speaker:

to associate any

Speaker:

disease outcome

Speaker:

with a drug, and

Speaker:

that's

Speaker:

where you stop.

Speaker:

That seems to be

Speaker:

my take on it to

Speaker:

a large extent.

Speaker:

Well, the shame

Speaker:

in it all is that

Speaker:

it's even worse

Speaker:

so than that,

Speaker:

because it'd be

Speaker:

great if they had

Speaker:

more, most GPs

Speaker:

have six months

Speaker:

to maybe a year,

Speaker:

depending upon

Speaker:

which school you

Speaker:

go to, in

Speaker:

exposure to

Speaker:

pharmacological

Speaker:

studies.

Speaker:

Do you know this?

Speaker:

It's six months

Speaker:

to a year.

Speaker:

No, I didn't.

Speaker:

Maximum year.

Speaker:

Maximum year.

Speaker:

That's

Speaker:

incredible.

Speaker:

Which is crazy,

Speaker:

because if you

Speaker:

think about it, a

Speaker:

pharmacist, most,

Speaker:

unless you do,

Speaker:

some pharmacists

Speaker:

are able to write

Speaker:

scripts, but you

Speaker:

have to go

Speaker:

through extensive

Speaker:

post-grad

Speaker:

certification

Speaker:

processes, very

Speaker:

few of

Speaker:

them have it.

Speaker:

Yet, all doctors

Speaker:

are able to write

Speaker:

a script that

Speaker:

have less

Speaker:

knowledge than

Speaker:

the pharmacist

Speaker:

does on what it

Speaker:

is that they're

Speaker:

prescribing.

Speaker:

That's

Speaker:

disconcerting to

Speaker:

say the least.

Speaker:

And again, it's

Speaker:

not the fault of the

Speaker:

physician, is it?

Speaker:

No, it's not.

Speaker:

Definitely not

Speaker:

the fault of the

Speaker:

physician.

Speaker:

Yeah.

Speaker:

That was just a

Speaker:

perfect podcast

Speaker:

in

Speaker:

itself, Justin.

Speaker:

And I sort of, I

Speaker:

love the way you

Speaker:

took that, the

Speaker:

fact that we sort

Speaker:

of really sort

Speaker:

of, and I should

Speaker:

probably send

Speaker:

this to my father

Speaker:

because he was

Speaker:

involved in

Speaker:

community

Speaker:

development for

Speaker:

years, but it's

Speaker:

almost like we've

Speaker:

got to sort of

Speaker:

rethink the

Speaker:

paradigm

Speaker:

completely and

Speaker:

sort of place

Speaker:

more emphasis on

Speaker:

the community.

Speaker:

How you then go

Speaker:

about educating

Speaker:

the masses, for

Speaker:

the want of

Speaker:

better word, is

Speaker:

probably another

Speaker:

question best

Speaker:

left to

Speaker:

another day.

Speaker:

But it does

Speaker:

make sense,

Speaker:

bringing the

Speaker:

awareness of

Speaker:

health to the

Speaker:

individual, and

Speaker:

almost from a

Speaker:

preventative

Speaker:

standpoint.

Speaker:

So encouraging

Speaker:

people to take,

Speaker:

how do I

Speaker:

put this?

Speaker:

Encouraging

Speaker:

people to take

Speaker:

responsibility

Speaker:

for their own

Speaker:

health and

Speaker:

creating

Speaker:

messaging

Speaker:

around that.

Speaker:

And I think

Speaker:

that's where the

Speaker:

biohacking

Speaker:

community is

Speaker:

effective.

Speaker:

I think it does

Speaker:

get a bit lost in

Speaker:

the weeds in

Speaker:

terms of maybe

Speaker:

focusing on the

Speaker:

minutiae more

Speaker:

often than the

Speaker:

actual needle

Speaker:

movers, which

Speaker:

just aren't sexy

Speaker:

at the end of the

Speaker:

day, are they?

Speaker:

Nobody wants to

Speaker:

necessarily sort

Speaker:

of go to bed when

Speaker:

it gets dark and

Speaker:

wake up when it

Speaker:

gets light.

Speaker:

They want to sort

Speaker:

of play around

Speaker:

with the red

Speaker:

light and the

Speaker:

$10,000 coin

Speaker:

plunge or

Speaker:

whatever it is.

Speaker:

So how you get

Speaker:

around that one?

Speaker:

It is

Speaker:

TVT.

Speaker:

Well, I want to come back down to

Speaker:

leadership

Speaker:

authority, and we

Speaker:

look into

Speaker:

different social

Speaker:

constructs and

Speaker:

theories around

Speaker:

that as well,

Speaker:

which begs the

Speaker:

question of like,

Speaker:

how much

Speaker:

authority are we

Speaker:

as a collective

Speaker:

giving those who

Speaker:

have voices?

Speaker:

And what are

Speaker:

their intentions?

Speaker:

Like, obviously

Speaker:

we all need to

Speaker:

make money in

Speaker:

this lifetime.

Speaker:

There's nothing

Speaker:

wrong with making

Speaker:

money, but I

Speaker:

think it's really

Speaker:

easy for me at

Speaker:

least, and maybe

Speaker:

this is a vouch

Speaker:

of advice for

Speaker:

anybody that may

Speaker:

consider

Speaker:

reviewing what it

Speaker:

is that they're

Speaker:

hearing.

Speaker:

Any moment when

Speaker:

an influencer of

Speaker:

any split in the

Speaker:

biohacking or policing

Speaker:

especially comes

Speaker:

with a polarized

Speaker:

view, I stop

Speaker:

listening

Speaker:

to them.

Speaker:

I stop listening

Speaker:

to them.

Speaker:

This is good for

Speaker:

you, this is bad

Speaker:

for you, blah,

Speaker:

blah, blah, blah,

Speaker:

blah, blah,

Speaker:

blah, blah.

Speaker:

Like, you know,

Speaker:

again, like for

Speaker:

example,

Speaker:

palm oil, palm

Speaker:

oil, okay, it's

Speaker:

terrible, but it

Speaker:

is terrible, but

Speaker:

it also has

Speaker:

certain potential

Speaker:

applications

Speaker:

outside of the

Speaker:

food industry.

Speaker:

Okay, so it's not

Speaker:

all bad.

Speaker:

Yes, there is

Speaker:

obviously an

Speaker:

impact that has

Speaker:

on nature, but

Speaker:

tell me what

Speaker:

doesn't have an

Speaker:

impact on nature

Speaker:

given the

Speaker:

technological

Speaker:

construct of

Speaker:

humanity.

Speaker:

You know, so

Speaker:

there are ways in

Speaker:

which we need to

Speaker:

mitigate that for

Speaker:

sure, but

Speaker:

nothing,

Speaker:

everything needs

Speaker:

to be considered

Speaker:

in content and

Speaker:

context and

Speaker:

content.

Speaker:

And a polarized

Speaker:

view often comes

Speaker:

with a bit of a

Speaker:

buy-in or a sale

Speaker:

for the person to

Speaker:

buy into, okay.

Speaker:

I'm not gonna

Speaker:

name any names,

Speaker:

but not too long

Speaker:

ago, there was a

Speaker:

very well-known

Speaker:

influencer in the

Speaker:

space who had

Speaker:

everything to say

Speaker:

about melatonin

Speaker:

and how it can

Speaker:

induce the

Speaker:

likelihood of an

Speaker:

increase of

Speaker:

myocardial

Speaker:

infarction.

Speaker:

And he cited

Speaker:

certain studies,

Speaker:

but anybody that

Speaker:

doesn't know how

Speaker:

to read studies

Speaker:

will just take

Speaker:

what he said for

Speaker:

face value, but

Speaker:

anybody that does

Speaker:

know how to read

Speaker:

a study will

Speaker:

actually look

Speaker:

into the

Speaker:

demographic of

Speaker:

which was

Speaker:

utilized for the

Speaker:

study and realize

Speaker:

that a lot of

Speaker:

these people

Speaker:

actually had

Speaker:

pre-existing

Speaker:

heart conditions

Speaker:

in the

Speaker:

first place.

Speaker:

These are not

Speaker:

healthy

Speaker:

individuals.

Speaker:

Yeah, no, it's

Speaker:

just so

Speaker:

context-dependent

Speaker:

at the end of the

Speaker:

day, isn't it?

Speaker:

And I love the

Speaker:

nutrition and

Speaker:

energy too.

Speaker:

It's ultimately

Speaker:

comes back to

Speaker:

sort of finding

Speaker:

that middle

Speaker:

ground, because

Speaker:

ultimately I feel

Speaker:

that we're all on

Speaker:

the bell curve

Speaker:

and obviously

Speaker:

you're going to

Speaker:

have extreme

Speaker:

outliers at

Speaker:

either end,

Speaker:

people who are

Speaker:

going to thrive

Speaker:

just caring for

Speaker:

this energy on a

Speaker:

carnival diet and

Speaker:

people who are

Speaker:

gonna thrive

Speaker:

maybe on a vegan

Speaker:

diet on the

Speaker:

other end.

Speaker:

But yeah, I think

Speaker:

ultimately we do

Speaker:

all sort of fall

Speaker:

somewhere in the

Speaker:

middle, don't we?

Speaker:

And it's

Speaker:

interesting to

Speaker:

see many of the

Speaker:

influences in

Speaker:

this space.

Speaker:

You're Paul

Speaker:

Saladinas of the

Speaker:

world, for

Speaker:

example, who sort

Speaker:

of started out

Speaker:

and maybe, I'm

Speaker:

not sure how many

Speaker:

people are aware

Speaker:

of this, but he

Speaker:

started out

Speaker:

vegan, then he

Speaker:

went fully

Speaker:

carnival.

Speaker:

And then he sort

Speaker:

of ended up

Speaker:

essentially an

Speaker:

omnivore in

Speaker:

the middle.

Speaker:

So I do think it

Speaker:

speaks to your

Speaker:

point in that

Speaker:

respect.

Speaker:

Anyway,

Speaker:

Justin, I think

Speaker:

we've already

Speaker:

been going for 14

Speaker:

minutes and

Speaker:

technically we

Speaker:

haven't even

Speaker:

started his

Speaker:

conversation.

Speaker:

So taking all

Speaker:

that into

Speaker:

account, and that

Speaker:

was truly the

Speaker:

most interesting

Speaker:

introduction to

Speaker:

Paul Saladinas,

Speaker:

so thank you.

Speaker:

Let's dive into

Speaker:

this concept of

Speaker:

immunometabolism.

Speaker:

Now, I think when

Speaker:

going into a

Speaker:

topic as complex,

Speaker:

potentially as

Speaker:

complex as this,

Speaker:

it's great to

Speaker:

have a baseline

Speaker:

and understanding

Speaker:

of the basic

Speaker:

physiology, the

Speaker:

basic

Speaker:

biochemistry.

Speaker:

So to start off

Speaker:

with, would you

Speaker:

mind breaking

Speaker:

down for the

Speaker:

listeners what

Speaker:

the immune system

Speaker:

fundamentally is?

Speaker:

And then we could

Speaker:

maybe branch into

Speaker:

more discussion

Speaker:

about how that

Speaker:

relates to

Speaker:

metabolism.

Speaker:

But yeah,

Speaker:

immunology 101,

Speaker:

as it were, would

Speaker:

you mind just

Speaker:

sort of providing

Speaker:

us with a

Speaker:

breakdown of the

Speaker:

concepts there?

Speaker:

It's an

Speaker:

environmental

Speaker:

foreman.

Speaker:

Let me explain.

Speaker:

So I was like,

Speaker:

what do you mean

Speaker:

environment

Speaker:

foreman?

Speaker:

It pretty much

Speaker:

directs what

Speaker:

needs to happen

Speaker:

between two

Speaker:

different

Speaker:

environment, well

Speaker:

within an

Speaker:

environment based

Speaker:

upon two

Speaker:

different

Speaker:

environments.

Speaker:

We live in an

Speaker:

environment, like

Speaker:

there is a

Speaker:

microcosm to the

Speaker:

macrocosm.

Speaker:

So we live in the

Speaker:

world, and the

Speaker:

world is a part

Speaker:

of the solar

Speaker:

system, and the

Speaker:

solar system is

Speaker:

part of the

Speaker:

galaxy, and the

Speaker:

galaxy is part of

Speaker:

the universe, and

Speaker:

there are

Speaker:

probably multiple

Speaker:

universes.

Speaker:

Maybe, maybe not.

Speaker:

I don't know, I'm

Speaker:

not a quantum

Speaker:

physicist, but I

Speaker:

would assume that

Speaker:

they are.

Speaker:

So within we take

Speaker:

the macro to the

Speaker:

macrocosm,

Speaker:

everything has

Speaker:

the potential of

Speaker:

symbiosis, or

Speaker:

conflict to that

Speaker:

symbiosis.

Speaker:

Now when conflict

Speaker:

exists to that

Speaker:

symbiosis, we

Speaker:

have to consider

Speaker:

what is it

Speaker:

between the two

Speaker:

environments

Speaker:

that's acting in

Speaker:

opposition to one

Speaker:

another.

Speaker:

And this is where

Speaker:

the immune system

Speaker:

comes in, because

Speaker:

it tries to sort

Speaker:

out the

Speaker:

oppositional

Speaker:

activities

Speaker:

between our

Speaker:

internal

Speaker:

environment as to

Speaker:

what's happening

Speaker:

outside of

Speaker:

ourselves.

Speaker:

So in the immune

Speaker:

system, the

Speaker:

immune system

Speaker:

itself, from a

Speaker:

scientific

Speaker:

perspective, you

Speaker:

have two major

Speaker:

components.

Speaker:

You have the

Speaker:

adaptive and the

Speaker:

innate

Speaker:

immune system.

Speaker:

The innate immune

Speaker:

system has been

Speaker:

around for a

Speaker:

lot longer.

Speaker:

The adaptive

Speaker:

immune system

Speaker:

came about

Speaker:

subsequently

Speaker:

thereafter.

Speaker:

The innate immune

Speaker:

system comprises

Speaker:

elements such as

Speaker:

macrophage, such

Speaker:

as neutrophils,

Speaker:

such as natural

Speaker:

killer cells and

Speaker:

granular

Speaker:

cytoplasmophils

Speaker:

and basophils.

Speaker:

They have less

Speaker:

specificity in

Speaker:

order to address

Speaker:

whatever burden

Speaker:

might be plaguing

Speaker:

the body, but

Speaker:

they have more

Speaker:

immediate

Speaker:

reactions.

Speaker:

And then in their

Speaker:

immediate

Speaker:

reaction,

Speaker:

particularly

Speaker:

dendritic cells,

Speaker:

they create what

Speaker:

they call

Speaker:

presentation.

Speaker:

They they

Speaker:

optimize.

Speaker:

Basically they

Speaker:

decorate what,

Speaker:

like for example,

Speaker:

a pathogen,

Speaker:

enabling the

Speaker:

adaptive immune

Speaker:

players, which

Speaker:

are your B and

Speaker:

your T

Speaker:

lymphocytes, to

Speaker:

come in and say,

Speaker:

okay, cool, these

Speaker:

guys

Speaker:

shouldn't be here.

Speaker:

And the B and the

Speaker:

T lymphocytes are

Speaker:

initially your

Speaker:

artillery,

Speaker:

because when we

Speaker:

get into the

Speaker:

solid danger

Speaker:

response part of

Speaker:

the discussion,

Speaker:

I'll explain it a

Speaker:

little bit more,

Speaker:

initially you

Speaker:

proliferate

Speaker:

T cells.

Speaker:

So the innate

Speaker:

immune system

Speaker:

will launch of

Speaker:

its defense.

Speaker:

And in doing so,

Speaker:

create APC and

Speaker:

then in that, the

Speaker:

body will create

Speaker:

a reaction in

Speaker:

releasing a lot

Speaker:

of naive or

Speaker:

increasing the

Speaker:

production of

Speaker:

your

Speaker:

naive T cells.

Speaker:

Then over time,

Speaker:

with the APC is

Speaker:

coming into

Speaker:

contact with

Speaker:

these particular

Speaker:

lymph node

Speaker:

points, then the

Speaker:

specific type of

Speaker:

T cells will

Speaker:

proliferate.

Speaker:

You have two

Speaker:

subsets in my T

Speaker:

helper cells, T

Speaker:

regulatory cells,

Speaker:

and then

Speaker:

cytotoxic

Speaker:

lymphocytes.

Speaker:

And then you also

Speaker:

have your

Speaker:

antibodies, the

Speaker:

cell that's

Speaker:

within your B

Speaker:

cell complexes,

Speaker:

your IgMs, your

Speaker:

IgGs, IgAs

Speaker:

and IgEs.

Speaker:

Depending upon

Speaker:

what it is,

Speaker:

that's within

Speaker:

those particular

Speaker:

antibodies and

Speaker:

that those

Speaker:

particular T cell

Speaker:

responses will

Speaker:

come into

Speaker:

the mix.

Speaker:

Now it's very

Speaker:

important that a

Speaker:

response is

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calibrated to a

Speaker:

point where it

Speaker:

doesn't cause

Speaker:

self-autoreactivity

Speaker:

in the body.

Speaker:

Otherwise you

Speaker:

have a state of

Speaker:

perpetual assault

Speaker:

that the immune

Speaker:

system perceives

Speaker:

that it is

Speaker:

required to

Speaker:

facilitate, even

Speaker:

though there

Speaker:

isn't a

Speaker:

continual threat.

Speaker:

Or there is no

Speaker:

longer the degree

Speaker:

of threat that it

Speaker:

perceives that it

Speaker:

actually has.

Speaker:

So it's very much

Speaker:

a concert.

Speaker:

And it's very

Speaker:

much like a

Speaker:

football game,

Speaker:

whereby the ball

Speaker:

is passed into

Speaker:

specific players

Speaker:

depending upon

Speaker:

the certain

Speaker:

sequence of how

Speaker:

the game is

Speaker:

playing out.

Speaker:

So those are your

Speaker:

two major

Speaker:

components that

Speaker:

you've been

Speaker:

using, the innate

Speaker:

and the adaptive

Speaker:

and obviously the

Speaker:

players.

Speaker:

What's very

Speaker:

interesting in

Speaker:

the innate immune

Speaker:

system is that

Speaker:

the stem cells

Speaker:

that produce most

Speaker:

of the innate

Speaker:

immune players

Speaker:

are lymphoid

Speaker:

stem cells.

Speaker:

Sorry, I'm sorry,

Speaker:

myeloid

Speaker:

stem cells.

Speaker:

Whereas the stem

Speaker:

cells that

Speaker:

produce most of

Speaker:

the adaptive

Speaker:

immune players

Speaker:

are lymphoid,

Speaker:

except albeit for

Speaker:

or natural

Speaker:

killer cells.

Speaker:

And this is

Speaker:

highly relevant

Speaker:

because your

Speaker:

natural killer

Speaker:

cells have the

Speaker:

greatest degree

Speaker:

of specificity in

Speaker:

contrast to the

Speaker:

other innate

Speaker:

immune players in

Speaker:

being able to

Speaker:

detect faulty

Speaker:

mutations.

Speaker:

So when you have

Speaker:

a lower natural

Speaker:

killer cells,

Speaker:

your risk of

Speaker:

cancer increases,

Speaker:

your body's

Speaker:

ability to resist

Speaker:

things like

Speaker:

perpetual cell

Speaker:

wall deficient

Speaker:

attacks such as

Speaker:

Lyme disease

Speaker:

reduces, your

Speaker:

body's ability to

Speaker:

mitigate

Speaker:

expression of

Speaker:

chronic envelope

Speaker:

based viruses

Speaker:

like

Speaker:

Epstein-Bach,

Speaker:

cyclo-mekovirus

Speaker:

decreases.

Speaker:

So when you have

Speaker:

lower natural

Speaker:

killer cells, you

Speaker:

become

Speaker:

vulnerable.

Speaker:

And what happens

Speaker:

is when you

Speaker:

become

Speaker:

vulnerable, the

Speaker:

other innate

Speaker:

players try to

Speaker:

step in because

Speaker:

there's a

Speaker:

deficiency of one

Speaker:

of their

Speaker:

teammates.

Speaker:

They try to come

Speaker:

in and help where

Speaker:

their teammates

Speaker:

not able to take

Speaker:

on the workload.

Speaker:

But in them doing

Speaker:

that, because of

Speaker:

their degree of

Speaker:

specificity isn't

Speaker:

as targeted as to

Speaker:

what natural

Speaker:

killer cells, and

Speaker:

it's also by way

Speaker:

of the stem cells

Speaker:

that they

Speaker:

originate from as

Speaker:

to why, this

Speaker:

creates a

Speaker:

likelihood of

Speaker:

perpetual,

Speaker:

chronic,

Speaker:

low-grade

Speaker:

inflammation.

Speaker:

Now, this

Speaker:

low-grade

Speaker:

inflammation can

Speaker:

also further

Speaker:

exhaust the

Speaker:

adaptive immune

Speaker:

system over time.

Speaker:

And HIV is a

Speaker:

classical

Speaker:

example.

Speaker:

You know, it's an

Speaker:

extreme example,

Speaker:

but it's a

Speaker:

classical example

Speaker:

of this whereby

Speaker:

HIV hijacks

Speaker:

certain

Speaker:

CD4 cells.

Speaker:

The CD4 cells

Speaker:

present

Speaker:

themselves along

Speaker:

the lymph nodes.

Speaker:

The innate immune

Speaker:

system launches

Speaker:

in a fence, but

Speaker:

meanwhile it's

Speaker:

launching in the

Speaker:

fence in the

Speaker:

wrong areas,

Speaker:

thereby reducing

Speaker:

the adaptive

Speaker:

capacity to

Speaker:

launch a

Speaker:

cytotoxic

Speaker:

lymphocyte

Speaker:

response at the

Speaker:

point where the

Speaker:

immune system

Speaker:

exhausts itself

Speaker:

and then you

Speaker:

develop eight.

Speaker:

Okay.

Speaker:

Would this be a,

Speaker:

excuse me, would

Speaker:

this be a point

Speaker:

where something

Speaker:

like a cytokine

Speaker:

resistance of

Speaker:

sorts would

Speaker:

develop,

Speaker:

potentially where

Speaker:

you've got an

Speaker:

anti-inflammatory

Speaker:

cytokin coming

Speaker:

into the mix, or

Speaker:

am I a bit off

Speaker:

base there?

Speaker:

I'm just trying

Speaker:

to piece this

Speaker:

together as you

Speaker:

go with regards

Speaker:

to the natural

Speaker:

killer cells.

Speaker:

Cytokin

Speaker:

resistance,

Speaker:

you're talking

Speaker:

about like

Speaker:

interleukin-10 as

Speaker:

a predominant

Speaker:

anti-cytokin.

Speaker:

Yes and no, and it's contextual,

Speaker:

because it

Speaker:

depends upon the

Speaker:

quantitative

Speaker:

release of other

Speaker:

cytokines in

Speaker:

ratio to that

Speaker:

interleukin-10

Speaker:

response.

Speaker:

As an example, if

Speaker:

you have a lot of

Speaker:

interleukin-4

Speaker:

being expressed

Speaker:

at the same time

Speaker:

as

Speaker:

interleukin-10,

Speaker:

and subsequently

Speaker:

you also might

Speaker:

have an

Speaker:

interleukin-13

Speaker:

activity

Speaker:

happening in

Speaker:

conjunction with

Speaker:

interleukin-4,

Speaker:

this may

Speaker:

propagate a

Speaker:

neutrophilic

Speaker:

response.

Speaker:

And the

Speaker:

neutrophilic

Speaker:

response can

Speaker:

increase the,

Speaker:

exacerbate a

Speaker:

release of

Speaker:

hydrogen

Speaker:

peroxide, which

Speaker:

is what they do.

Speaker:

That's where

Speaker:

hydrogen peroxide

Speaker:

is actually part

Speaker:

of the

Speaker:

immune system.

Speaker:

Immune system

Speaker:

actually release

Speaker:

hydrogen peroxide

Speaker:

as a form of very

Speaker:

strong

Speaker:

anti-microbial.

Speaker:

This is why, like

Speaker:

if you've had

Speaker:

hydrogen peroxide

Speaker:

IDs and so on,

Speaker:

it's because it's

Speaker:

supporting an

Speaker:

exhausted immune

Speaker:

system, this FYI.

Speaker:

Interesting.

Speaker:

Yeah, no, that's

Speaker:

a tip that I do

Speaker:

not know.

Speaker:

So with this

Speaker:

whole paradigm,

Speaker:

it's not just

Speaker:

about like, okay,

Speaker:

interleukin-10 is

Speaker:

there, we're

Speaker:

still having

Speaker:

information.

Speaker:

Well, no, it's,

Speaker:

it's looking at

Speaker:

it as doing what

Speaker:

it needs to do,

Speaker:

but what else is

Speaker:

going on in this

Speaker:

whole paradigm?

Speaker:

And this is where

Speaker:

like measuring a

Speaker:

cytokine map

Speaker:

provides to be

Speaker:

incredibly useful

Speaker:

when you're

Speaker:

seeing the

Speaker:

complex activity

Speaker:

of the entire

Speaker:

immune system.

Speaker:

You know, two

Speaker:

tests that I

Speaker:

always, not

Speaker:

always, but that

Speaker:

I enjoy running

Speaker:

because I get so

Speaker:

much insight from

Speaker:

them,

Speaker:

particularly in

Speaker:

cases of chronic

Speaker:

fatigue, not

Speaker:

necessarily

Speaker:

always long walk

Speaker:

over, just

Speaker:

chronic fatigue

Speaker:

cases, because in

Speaker:

my clinical

Speaker:

experience, in

Speaker:

supporting those

Speaker:

with chronic

Speaker:

fatigue, 90% of

Speaker:

the time it has

Speaker:

an association

Speaker:

with a exhausted

Speaker:

natural killer

Speaker:

cell response and

Speaker:

subsequently a

Speaker:

perpetuated

Speaker:

monocyte

Speaker:

inflammatory

Speaker:

response.

Speaker:

So in these

Speaker:

cases, they

Speaker:

always, no matter

Speaker:

how much iron or

Speaker:

iron-rich foods

Speaker:

they eat, they

Speaker:

always have low

Speaker:

serum iron.

Speaker:

If this is you,

Speaker:

and I'm speaking

Speaker:

to the audience

Speaker:

now, if you eat a

Speaker:

lot of red meat,

Speaker:

you're taking

Speaker:

trimethylglycine

Speaker:

to help with

Speaker:

hyperchloridea in

Speaker:

case you may have

Speaker:

that and try to

Speaker:

absorb

Speaker:

iron better.

Speaker:

And yet your

Speaker:

serum iron

Speaker:

concentration is

Speaker:

always on the low

Speaker:

side or maybe

Speaker:

even deficient,

Speaker:

despite the fact

Speaker:

that you might be

Speaker:

eating it's a

Speaker:

kilogram of

Speaker:

steak a day.

Speaker:

Whether you are

Speaker:

or you're not, if

Speaker:

it is that you're

Speaker:

full of this

Speaker:

paradigm and yet

Speaker:

no matter what

Speaker:

you do, albeit

Speaker:

from maybe direct

Speaker:

super

Speaker:

thermal iron,

Speaker:

your iron levels

Speaker:

are always

Speaker:

suppressed.

Speaker:

Consider the fact

Speaker:

that your

Speaker:

monocytes are

Speaker:

microphage on a

Speaker:

state of

Speaker:

perpetual

Speaker:

reactivation.

Speaker:

Okay, they're in

Speaker:

a state of M1,

Speaker:

microphage,

Speaker:

immunotype.

Speaker:

And this is

Speaker:

really elusive

Speaker:

because like, if

Speaker:

you just look

Speaker:

into a white

Speaker:

blood salt

Speaker:

differential to

Speaker:

try and determine

Speaker:

whether or not

Speaker:

this is

Speaker:

happening,

Speaker:

it doesn't always

Speaker:

show itself on a

Speaker:

standard white

Speaker:

blood salt

Speaker:

differential

Speaker:

because unless

Speaker:

you're gonna do

Speaker:

immunological

Speaker:

survey every day

Speaker:

for a period of

Speaker:

seven days, in

Speaker:

these particular

Speaker:

cases, you're not

Speaker:

always

Speaker:

necessarily gonna

Speaker:

get the window

Speaker:

within which the

Speaker:

immune systems

Speaker:

are compromised,

Speaker:

showing the true

Speaker:

effect of what

Speaker:

isn't or what is

Speaker:

actually

Speaker:

going on.

Speaker:

So this is where

Speaker:

running a

Speaker:

lymphocyte flow

Speaker:

cytometry as well

Speaker:

as a cytokine

Speaker:

map, proves to be

Speaker:

incredibly

Speaker:

insightful

Speaker:

because this

Speaker:

gives more of the

Speaker:

specificity in

Speaker:

terms of like

Speaker:

microphage

Speaker:

inflammatory

Speaker:

proteins and so

Speaker:

on and other side

Speaker:

of kinds of that

Speaker:

nature that could

Speaker:

be expressed in

Speaker:

the background,

Speaker:

actually

Speaker:

impacting anemia,

Speaker:

iron-based

Speaker:

anemia.

Speaker:

Again, despite

Speaker:

the fact of any

Speaker:

supplementation

Speaker:

or nutritional

Speaker:

augmentation,

Speaker:

when one is

Speaker:

experiencing

Speaker:

perpetual

Speaker:

iron-based

Speaker:

anemia,

Speaker:

especially in

Speaker:

situations where

Speaker:

they have

Speaker:

supplements, that

Speaker:

comes to consider

Speaker:

that there is an

Speaker:

immunological or

Speaker:

an immunological

Speaker:

distorted

Speaker:

perception

Speaker:

going on.

Speaker:

And I think

Speaker:

that's really

Speaker:

important is

Speaker:

that, yes, the

Speaker:

immune system can

Speaker:

exhaust itself,

Speaker:

however, it's not

Speaker:

always the point,

Speaker:

it's like the

Speaker:

whole concept

Speaker:

behind adrenal

Speaker:

exhaustion.

Speaker:

Do the adrenal

Speaker:

glands really

Speaker:

exhaust

Speaker:

themselves or is

Speaker:

it the receptor

Speaker:

makeup that

Speaker:

actually starts

Speaker:

to lose the

Speaker:

sensitivity to

Speaker:

the effect of the

Speaker:

glucocorticoids?

Speaker:

Or is it the fact

Speaker:

that it redirects

Speaker:

your other

Speaker:

catecholamines or

Speaker:

other hormone

Speaker:

specifically to

Speaker:

try and maintain

Speaker:

the state of pH

Speaker:

in the body?

Speaker:

The organic

Speaker:

gradient

Speaker:

in the body.

Speaker:

So again, the

Speaker:

immune system is

Speaker:

the same, is

Speaker:

that, I guess, in

Speaker:

most only you can

Speaker:

get exhausted and

Speaker:

certain

Speaker:

components of the

Speaker:

immune system can

Speaker:

tire, but you

Speaker:

have to ask

Speaker:

yourself why?

Speaker:

Why is the immune

Speaker:

system exhausted

Speaker:

in its cytotoxic

Speaker:

effect, for

Speaker:

example?

Speaker:

And often the

Speaker:

answer is because

Speaker:

there's an

Speaker:

imbalance between

Speaker:

its innate and

Speaker:

adaptive

Speaker:

components.

Speaker:

Yeah, that was

Speaker:

truly, I could

Speaker:

have used all of

Speaker:

that when

Speaker:

prepping for this

Speaker:

episode, that

Speaker:

would have made

Speaker:

life a lot easier

Speaker:

instead of trying

Speaker:

to sort of figure

Speaker:

out the

Speaker:

immunology from

Speaker:

scratch, which I

Speaker:

will fully admit,

Speaker:

I am not that

Speaker:

proficient in.

Speaker:

So I will for one

Speaker:

will be relisting

Speaker:

to all of that

Speaker:

because

Speaker:

truthfully I'm

Speaker:

talking about 80%

Speaker:

of it, some of it

Speaker:

was beyond me,

Speaker:

however, that was

Speaker:

incredible,

Speaker:

thank you.

Speaker:

And the audience

Speaker:

listening, you

Speaker:

may be a bit

Speaker:

flummoxed by

Speaker:

that, but I think

Speaker:

if you were to

Speaker:

give it a second

Speaker:

listen after

Speaker:

having listened

Speaker:

to the rest of

Speaker:

the episode, of

Speaker:

course, you will

Speaker:

pick up on a lot

Speaker:

of what Justin

Speaker:

just said.

Speaker:

And I know going

Speaker:

forwards, that's

Speaker:

going to really

Speaker:

help the rest of

Speaker:

the discussion

Speaker:

that we're going

Speaker:

to have about the

Speaker:

sort of concept

Speaker:

of

Speaker:

immunomatabolism,

Speaker:

which really is a

Speaker:

perfect segue

Speaker:

into that, into

Speaker:

this concept of

Speaker:

immunomatabolism.

Speaker:

And the way I

Speaker:

understand it,

Speaker:

sort of at a very

Speaker:

layman's

Speaker:

level is that

Speaker:

the immune system

Speaker:

obviously at

Speaker:

higher levels,

Speaker:

what controls the

Speaker:

inflammatory

Speaker:

response

Speaker:

in the body.

Speaker:

And when that

Speaker:

inflammatory

Speaker:

response is out

Speaker:

of control, then

Speaker:

there's a strong

Speaker:

carry over to

Speaker:

what is

Speaker:

colloquially

Speaker:

known as

Speaker:

metabolism.

Speaker:

That being the

Speaker:

result or the

Speaker:

collection of

Speaker:

various organ

Speaker:

systems

Speaker:

throughout the

Speaker:

body, everything

Speaker:

from thyroid to

Speaker:

pancreatic and

Speaker:

insulin function,

Speaker:

et cetera.

Speaker:

And I'd love to

Speaker:

sort of chat

Speaker:

about those

Speaker:

upstream

Speaker:

triggers points

Speaker:

in a bit.

Speaker:

But to start off

Speaker:

with, would you

Speaker:

sort of mind

Speaker:

breaking down the

Speaker:

way you see

Speaker:

immunomatabolism?

Speaker:

Because I think

Speaker:

I've got the gist

Speaker:

of it, but not

Speaker:

entirely.

Speaker:

So would you

Speaker:

provide the

Speaker:

audience with a

Speaker:

breakdown of this

Speaker:

term and then we

Speaker:

can discuss it in

Speaker:

a bit more depth

Speaker:

from there.

Speaker:

Well, I've got to

Speaker:

give credit to

Speaker:

Professor

Speaker:

Robert Naviou.

Speaker:

You know, that's

Speaker:

the cornerstone

Speaker:

of my

Speaker:

understanding

Speaker:

behind this

Speaker:

concept.

Speaker:

There are others

Speaker:

that definitely

Speaker:

contributed

Speaker:

toward it.

Speaker:

But by far he's

Speaker:

being the most

Speaker:

influential in

Speaker:

alluding to my

Speaker:

understanding as

Speaker:

to what this

Speaker:

paradigm actually

Speaker:

entails.

Speaker:

I mentioned

Speaker:

Albert Zangorgi

Speaker:

before when I was

Speaker:

talking about

Speaker:

methylene blue.

Speaker:

He also went into

Speaker:

this prior

Speaker:

to Naviou.

Speaker:

And prior to that

Speaker:

generation was

Speaker:

John Beard back

Speaker:

in the early part

Speaker:

of the 1900s, who

Speaker:

was the first to

Speaker:

treat cancer by

Speaker:

injecting

Speaker:

digestive enzymes

Speaker:

into tumors.

Speaker:

So this whole

Speaker:

paradigm is

Speaker:

actually started

Speaker:

by looking at

Speaker:

cancer as a

Speaker:

physiological

Speaker:

process, right?

Speaker:

And then

Speaker:

determining what

Speaker:

was going on

Speaker:

within cancer.

Speaker:

But then

Speaker:

obviously then as

Speaker:

time went on, it

Speaker:

actually was made

Speaker:

apparent

Speaker:

that the rate of

Speaker:

respiratory chain

Speaker:

activity has a

Speaker:

dramatic impact

Speaker:

over the

Speaker:

availability of

Speaker:

ATP, but not only

Speaker:

the availability

Speaker:

of ATP, it's

Speaker:

potential

Speaker:

oxidative

Speaker:

byproducts.

Speaker:

So mitochondria

Speaker:

produce a lot of

Speaker:

oxidants because

Speaker:

they produce a

Speaker:

lot of energy,

Speaker:

which means that

Speaker:

their membranes

Speaker:

are highly

Speaker:

susceptible to

Speaker:

oxidative stress

Speaker:

if they're not

Speaker:

maintained in a

Speaker:

neutral anhydrous

Speaker:

state, okay?

Speaker:

Like a battery.

Speaker:

You have to think

Speaker:

of your

Speaker:

mitochondria like

Speaker:

a battery.

Speaker:

If the polarity

Speaker:

or the ion

Speaker:

exchange is not

Speaker:

in well balanced

Speaker:

within

Speaker:

mitochondria,

Speaker:

that battery gets

Speaker:

hot, okay?

Speaker:

And what can

Speaker:

induce this if we

Speaker:

do not, or if our

Speaker:

mitochondria

Speaker:

don't have the

Speaker:

capacity to

Speaker:

readily shift

Speaker:

from different

Speaker:

energy dynamics,

Speaker:

meaning from

Speaker:

something as

Speaker:

immediate as the

Speaker:

creatine

Speaker:

phosphate system

Speaker:

to the

Speaker:

glycolysis, to

Speaker:

triclobolic acid,

Speaker:

to electron

Speaker:

transport chain

Speaker:

and shifting.

Speaker:

Because the thing

Speaker:

is you shouldn't

Speaker:

just do one.

Speaker:

Like there is a

Speaker:

flow of them all

Speaker:

happening

Speaker:

simultaneously

Speaker:

but to varying

Speaker:

degrees.

Speaker:

But when there's

Speaker:

a requirement in

Speaker:

the shift to take

Speaker:

place into a more

Speaker:

predominant state

Speaker:

of respiratory

Speaker:

chain activity,

Speaker:

energy

Speaker:

production, and

Speaker:

that shift can't

Speaker:

take place

Speaker:

effectively, then

Speaker:

what happens is

Speaker:

these

Speaker:

mitochondria

Speaker:

become highly

Speaker:

radical.

Speaker:

So they start to

Speaker:

not only damage

Speaker:

their own DNA but

Speaker:

they start to

Speaker:

damage DNA within

Speaker:

proximity from

Speaker:

expression from

Speaker:

the nucleus of

Speaker:

the cell.

Speaker:

And this is where

Speaker:

over time you can

Speaker:

start to have

Speaker:

mutations occur

Speaker:

as well.

Speaker:

Albeit that even

Speaker:

prior to these

Speaker:

mutations

Speaker:

occurring an

Speaker:

increase in the

Speaker:

likelihood of a

Speaker:

concept called

Speaker:

immunological

Speaker:

citizens may take

Speaker:

place as well.

Speaker:

So metabolism,

Speaker:

immunology, what

Speaker:

was the term?

Speaker:

How did you

Speaker:

connect

Speaker:

those two terms?

Speaker:

The idea of sort

Speaker:

of

Speaker:

immunomatabolism.

Speaker:

Immunomatabolism

Speaker:

of our, see the

Speaker:

moments of the

Speaker:

light

Speaker:

dislikes here.

Speaker:

Immunomatabolism

Speaker:

really is, as you

Speaker:

mentioned, the

Speaker:

segue between how

Speaker:

the internal

Speaker:

environment of

Speaker:

our physiology is

Speaker:

responding to

Speaker:

stimuli from our

Speaker:

external

Speaker:

environment.

Speaker:

And subsequently

Speaker:

within that

Speaker:

response, how

Speaker:

well we are

Speaker:

managing the

Speaker:

production as

Speaker:

well as recycling

Speaker:

of energy.

Speaker:

So going back to

Speaker:

Professor

Speaker:

Navia's work,

Speaker:

there he created

Speaker:

a concept called

Speaker:

the cell danger

Speaker:

response state,

Speaker:

which involves

Speaker:

different states

Speaker:

of respiratory

Speaker:

chain activity in

Speaker:

the mitochondria,

Speaker:

going from a

Speaker:

neutral, or I'm

Speaker:

gonna say a

Speaker:

neutral state, a

Speaker:

energetically

Speaker:

efficient state.

Speaker:

So think of your

Speaker:

mitochondria when

Speaker:

they're like

Speaker:

nuclear power

Speaker:

plants, meaning

Speaker:

they produce a

Speaker:

lot of energy

Speaker:

with a high

Speaker:

energy yield, but

Speaker:

a low

Speaker:

energy cost.

Speaker:

That's when

Speaker:

they're in their

Speaker:

energetic,

Speaker:

optimized state.

Speaker:

Okay, so they are

Speaker:

nuclear

Speaker:

power plants.

Speaker:

That would be CDR3.

Speaker:

No, no, that's a

Speaker:

neutral CDR.

Speaker:

That's CDR0,

Speaker:

think about it.

Speaker:

Okay, all right.

Speaker:

That's your, the

Speaker:

top part of

Speaker:

the wheel.

Speaker:

And then what

Speaker:

happens is when

Speaker:

you initially

Speaker:

have a threat, it

Speaker:

doesn't have to

Speaker:

be a

Speaker:

pathogenic threat.

Speaker:

It can be a

Speaker:

toxin, it can be

Speaker:

a heavy metal, it

Speaker:

could be

Speaker:

psychological

Speaker:

threats, it could

Speaker:

be persistent

Speaker:

organic

Speaker:

pollutants.

Speaker:

You name it.

Speaker:

When there's an

Speaker:

initial threat of

Speaker:

which the immune

Speaker:

system perceives

Speaker:

that it needs to

Speaker:

create a specific

Speaker:

response to, then

Speaker:

the mitochondria

Speaker:

shift into a

Speaker:

CDR1 state.

Speaker:

This is where

Speaker:

they become more

Speaker:

glycolytically

Speaker:

dominant.

Speaker:

Now, which is

Speaker:

very natural, and

Speaker:

just by the way,

Speaker:

the mitochondria

Speaker:

are continually

Speaker:

shifting in and

Speaker:

out of these

Speaker:

different cell

Speaker:

danger

Speaker:

response states.

Speaker:

But it's

Speaker:

important that

Speaker:

they're able to

Speaker:

shift and they

Speaker:

don't get stuck.

Speaker:

Okay, the reason

Speaker:

as to why they

Speaker:

get stuck is

Speaker:

very, are very

Speaker:

complex, because

Speaker:

now we're looking

Speaker:

at an interplay

Speaker:

between endocrine

Speaker:

and neurological,

Speaker:

immunological,

Speaker:

which actually

Speaker:

there's Leo

Speaker:

Prambro, of which

Speaker:

we both know of.

Speaker:

He also created a

Speaker:

category

Speaker:

entitled

Speaker:

psychoneuroimmunology,

Speaker:

which pretty much

Speaker:

embodies a lot of

Speaker:

this work

Speaker:

as well.

Speaker:

But he puts it

Speaker:

into a construct

Speaker:

of not only that

Speaker:

of apparent

Speaker:

physiology, but

Speaker:

also

Speaker:

psychological,

Speaker:

even spiritual

Speaker:

processes, which

Speaker:

I'm very much

Speaker:

aligned into his

Speaker:

theories as well.

Speaker:

Yet, we go back

Speaker:

to Navio's work,

Speaker:

the cell danger

Speaker:

one is when you

Speaker:

become more

Speaker:

glycolytically

Speaker:

dominant.

Speaker:

So what happens

Speaker:

here is that the

Speaker:

mitochondria are

Speaker:

going to be more

Speaker:

readily engaged,

Speaker:

augmented,

Speaker:

responsive, are

Speaker:

gonna be more

Speaker:

responsive to

Speaker:

within the use of

Speaker:

glucose as an

Speaker:

energy fuel

Speaker:

source, right?

Speaker:

Glucose and

Speaker:

pyruvate and so

Speaker:

on, rather than

Speaker:

being able to

Speaker:

utilize a vast

Speaker:

degree of

Speaker:

precursors to

Speaker:

pyruvate, such as

Speaker:

fats and

Speaker:

amino acids.

Speaker:

So what happens

Speaker:

here is that you

Speaker:

create a

Speaker:

maladaptive

Speaker:

response if you

Speaker:

get stuck in the

Speaker:

CDR1 state,

Speaker:

whereby the

Speaker:

mitochondria are

Speaker:

like, okay, we

Speaker:

need glucose, we

Speaker:

need glucose, and

Speaker:

you start having

Speaker:

increased sugar

Speaker:

cravings.

Speaker:

And subsequently,

Speaker:

this is where it

Speaker:

starts, right?

Speaker:

And then the

Speaker:

increase of sugar

Speaker:

cravings can also

Speaker:

have an impact on

Speaker:

driving down

Speaker:

methylation

Speaker:

because sugar

Speaker:

depletes

Speaker:

methyl donors.

Speaker:

And this is where

Speaker:

it can really

Speaker:

become a storm.

Speaker:

Not only a

Speaker:

cytokine storm,

Speaker:

but also a storm

Speaker:

on your

Speaker:

neurotransmitter

Speaker:

makeup.

Speaker:

So you start to

Speaker:

be able to

Speaker:

produce less

Speaker:

dopamine, you

Speaker:

start to have

Speaker:

dysregulated

Speaker:

production of

Speaker:

serotonin, you

Speaker:

start to have

Speaker:

exacerbated

Speaker:

expression of

Speaker:

extracellular

Speaker:

glutamate, not

Speaker:

intracellular,

Speaker:

extracellular

Speaker:

glutamate.

Speaker:

You start to

Speaker:

downregulate your

Speaker:

gamma-minipituric

Speaker:

acid receptor

Speaker:

sensitivity

Speaker:

because you're

Speaker:

not producing

Speaker:

enough of it

Speaker:

because the

Speaker:

extracellular

Speaker:

glutamate is

Speaker:

preventing you

Speaker:

from doing so.

Speaker:

And these are all

Speaker:

the unfortunate

Speaker:

consequences that

Speaker:

occur with

Speaker:

habitual excess

Speaker:

of sugar intake.

Speaker:

Now, this state

Speaker:

CDR1 is also

Speaker:

associated to an

Speaker:

immunological

Speaker:

phenotype called

Speaker:

TH2 dominant, of

Speaker:

which I've just

Speaker:

written a

Speaker:

book about.

Speaker:

And it's a book

Speaker:

that will be

Speaker:

facing for

Speaker:

practitioners as

Speaker:

well as for

Speaker:

the laymen.

Speaker:

So we'll have all

Speaker:

the complex words

Speaker:

that I've thrown

Speaker:

around today.

Speaker:

We'll have some

Speaker:

words that people

Speaker:

understand.

Speaker:

And the book for

Speaker:

the laymen is

Speaker:

entitled

Speaker:

"Responsible

Speaker:

Living, Moving

Speaker:

Away From

Speaker:

Reactivity."

Speaker:

And this is

Speaker:

really important

Speaker:

because our

Speaker:

bodies have

Speaker:

veered into

Speaker:

states of

Speaker:

reactivity

Speaker:

without us even

Speaker:

realizing it.

Speaker:

And the CDR1,

Speaker:

when we get stuck

Speaker:

here, we also

Speaker:

propensiate the

Speaker:

release of

Speaker:

histamine, which

Speaker:

creates fibrosis,

Speaker:

which causes poor

Speaker:

microvasculature,

Speaker:

which does not

Speaker:

enable things

Speaker:

such as an

Speaker:

example, thyroid

Speaker:

hormone, from

Speaker:

being able to

Speaker:

reach certain

Speaker:

receptors in the

Speaker:

mitochondrial

Speaker:

space to induce

Speaker:

support of

Speaker:

oxidant-phosphorylated

Speaker:

pathways, which

Speaker:

thyroid hormone

Speaker:

is highly

Speaker:

responsible

Speaker:

for doing.

Speaker:

Start protein

Speaker:

expression and

Speaker:

all of that.

Speaker:

Exactly right,

Speaker:

exactly right.

Speaker:

So this is CDR1.

Speaker:

And often people

Speaker:

get stuck here

Speaker:

because, again,

Speaker:

when we're young

Speaker:

and our DNA can

Speaker:

replicate at a

Speaker:

quicker pace, we

Speaker:

can recover.

Speaker:

But as soon as we

Speaker:

get to like 33,

Speaker:

that varies from

Speaker:

person to person.

Speaker:

That's the first

Speaker:

switch that

Speaker:

occurs as to when

Speaker:

our DNA

Speaker:

replication

Speaker:

starts to

Speaker:

slow down.

Speaker:

And this is where

Speaker:

we have an

Speaker:

increase of

Speaker:

senescence

Speaker:

starting

Speaker:

to come up.

Speaker:

And then

Speaker:

obviously that

Speaker:

proliferates as

Speaker:

we get over the

Speaker:

age of 55, it

Speaker:

really

Speaker:

proliferates.

Speaker:

So in our current

Speaker:

time, when you're

Speaker:

young, 20s and

Speaker:

you're a

Speaker:

youngster, you

Speaker:

don't feel it as

Speaker:

much, but without

Speaker:

a doubt, you're

Speaker:

being exposed to

Speaker:

it and you'll

Speaker:

start to

Speaker:

feel it later.

Speaker:

And it's been

Speaker:

reported that

Speaker:

those who were

Speaker:

born in our

Speaker:

generation may

Speaker:

not even live as

Speaker:

long as our

Speaker:

parents'

Speaker:

generation,

Speaker:

right?

Speaker:

Despite the

Speaker:

medical

Speaker:

advancements.

Speaker:

And there's

Speaker:

obviously, it's a

Speaker:

polarized

Speaker:

perspective,

Speaker:

again, the

Speaker:

courses of

Speaker:

polarity,

Speaker:

but it does make

Speaker:

consideration as

Speaker:

to where it is.

Speaker:

And these

Speaker:

suggestive

Speaker:

probabilities

Speaker:

that would come

Speaker:

about just by

Speaker:

opinion, that

Speaker:

came about from

Speaker:

actually looking

Speaker:

into the increase

Speaker:

of

Speaker:

non-conventional

Speaker:

disease and the

Speaker:

subsequent

Speaker:

shortening of

Speaker:

lifespan,

Speaker:

depending

Speaker:

upon that.

Speaker:

And also

Speaker:

financial

Speaker:

constraints that

Speaker:

come about with

Speaker:

non-conventional

Speaker:

disease, because

Speaker:

it's one thing to

Speaker:

have medical

Speaker:

advancements, but

Speaker:

it's another

Speaker:

thing to

Speaker:

look at, right?

Speaker:

So we're actually

Speaker:

living in a very

Speaker:

interesting time

Speaker:

where we have a

Speaker:

lot of

Speaker:

innovation, but

Speaker:

yet we're still

Speaker:

exposed to the

Speaker:

onslaught of

Speaker:

continual stress.

Speaker:

Now, one of the

Speaker:

bigger stressors

Speaker:

that I think is

Speaker:

not considered

Speaker:

are the unseen

Speaker:

stressors

Speaker:

like EMF.

Speaker:

Without a doubt,

Speaker:

non-native EMF is

Speaker:

by far the

Speaker:

biggest toxin of

Speaker:

our age, by far.

Speaker:

Without a doubt,

Speaker:

there's a-- Ooh,

Speaker:

there's a

Speaker:

decisive

Speaker:

statement.

Speaker:

Yeah, absolutely.

Speaker:

And I'm also,

Speaker:

like I mentioned

Speaker:

before, be

Speaker:

careful when you

Speaker:

have people

Speaker:

saying, decisive

Speaker:

statements in

Speaker:

this instance,

Speaker:

and I'm very,

Speaker:

very, very

Speaker:

critical of being

Speaker:

objective.

Speaker:

But in this

Speaker:

instance, I am

Speaker:

passionately

Speaker:

committed to the

Speaker:

statement that

Speaker:

non-native EMF is

Speaker:

by far the

Speaker:

greatest toxin of

Speaker:

our age.

Speaker:

The influx of

Speaker:

patients

Speaker:

struggling with

Speaker:

chronic fatigue,

Speaker:

struggling with

Speaker:

different forms

Speaker:

of neurodiversity

Speaker:

since the

Speaker:

introduction of

Speaker:

5G towers is very

Speaker:

apparent.

Speaker:

Not only in my

Speaker:

practice, but

Speaker:

many other

Speaker:

doctors and

Speaker:

physicians, which

Speaker:

I work in

Speaker:

community with,

Speaker:

have also

Speaker:

experienced the

Speaker:

same thing.

Speaker:

So in essence,

Speaker:

not to go down

Speaker:

that rabbit hole,

Speaker:

because Alice is

Speaker:

waiting with a

Speaker:

mad hatcher to

Speaker:

really go down

Speaker:

the tangent.

Speaker:

So just to avoid

Speaker:

that tangent, and

Speaker:

the point I'm

Speaker:

trying to make is

Speaker:

we live in a time

Speaker:

where we are

Speaker:

perpetually

Speaker:

exposed to many

Speaker:

stressors, more

Speaker:

so than what we

Speaker:

actually might

Speaker:

give credit to,

Speaker:

and may give

Speaker:

awareness to.

Speaker:

And because of

Speaker:

this, it is by

Speaker:

natural default,

Speaker:

because I mean,

Speaker:

evolution takes a

Speaker:

lot longer than

Speaker:

technological

Speaker:

evolution

Speaker:

has taken.

Speaker:

So the

Speaker:

mitochondria have

Speaker:

adapted pretty

Speaker:

well, very

Speaker:

quickly, but they

Speaker:

still haven't

Speaker:

adapted to what

Speaker:

it is we expose

Speaker:

them to in our

Speaker:

current daily

Speaker:

basis,

Speaker:

current times.

Speaker:

So what we're

Speaker:

finding, what

Speaker:

I've found, and

Speaker:

other

Speaker:

practitioners as

Speaker:

well, is that

Speaker:

people can

Speaker:

momentarily move

Speaker:

out of these

Speaker:

states, you know,

Speaker:

if they implement

Speaker:

all the biohacks

Speaker:

and they change

Speaker:

their lifestyle

Speaker:

and so on, but

Speaker:

the older that

Speaker:

they get, the

Speaker:

more inclined

Speaker:

they are to stay

Speaker:

stuck in the CDR1

Speaker:

state, okay?

Speaker:

Which is very

Speaker:

closely

Speaker:

associated to

Speaker:

chronic low grade

Speaker:

information.

Speaker:

And again, in

Speaker:

influencing

Speaker:

metabolic

Speaker:

resistance,

Speaker:

because when the

Speaker:

mitochondria

Speaker:

become more

Speaker:

glycolytically

Speaker:

dominant, they

Speaker:

can look for

Speaker:

glucose.

Speaker:

They're not gonna

Speaker:

utilize fat

Speaker:

effectively.

Speaker:

So beta-oxidation

Speaker:

goes down, which

Speaker:

means you have

Speaker:

extracellular

Speaker:

ketones

Speaker:

propagating,

Speaker:

which also causes

Speaker:

more lipid

Speaker:

peroxidation, and

Speaker:

other cumulative

Speaker:

issues between

Speaker:

cells comes into

Speaker:

the equation.

Speaker:

So it's quite an

Speaker:

intense paradigm,

Speaker:

to understand,

Speaker:

but it's an

Speaker:

important concept

Speaker:

to understand.

Speaker:

When we get into

Speaker:

cell danger two

Speaker:

response state,

Speaker:

this is where we

Speaker:

have a

Speaker:

proliferated

Speaker:

mTOR.

Speaker:

Just one question

Speaker:

before we jump

Speaker:

into CD2, if

Speaker:

that's okay.

Speaker:

You mentioned

Speaker:

earlier that

Speaker:

isolation is

Speaker:

potentially,

Speaker:

aside from

Speaker:

non-native EMFs,

Speaker:

of course, is

Speaker:

potentially one

Speaker:

of the biggest

Speaker:

triggers of the

Speaker:

slow grade

Speaker:

inflammation.

Speaker:

Do you think, and

Speaker:

I'm just thinking

Speaker:

of myself,

Speaker:

subjectively from

Speaker:

this, when saying

Speaker:

this, but when I

Speaker:

was younger, I

Speaker:

was definitely

Speaker:

more able, and

Speaker:

this speaks to

Speaker:

what you were

Speaker:

saying earlier

Speaker:

about us really

Speaker:

being more

Speaker:

gregarious than

Speaker:

we think we are,

Speaker:

I was really able

Speaker:

to function more

Speaker:

in a sort of an

Speaker:

isolated

Speaker:

capacity.

Speaker:

I found I wasn't

Speaker:

that being

Speaker:

isolated, I

Speaker:

wasn't subject to

Speaker:

feeling the way I

Speaker:

do now, which as

Speaker:

we talked about,

Speaker:

I'm going through

Speaker:

some, my own sort

Speaker:

of

Speaker:

post-phylophoty

Speaker:

with COVID,

Speaker:

et cetera.

Speaker:

And maybe that is

Speaker:

a mitigating

Speaker:

factor thereof,

Speaker:

but sort of

Speaker:

almost

Speaker:

independently of

Speaker:

that, and maybe

Speaker:

prior to COVID, I

Speaker:

found that the

Speaker:

more time I

Speaker:

spent alone,

Speaker:

as I got older, I

Speaker:

would, yeah, I

Speaker:

would definitely

Speaker:

become more

Speaker:

systemically

Speaker:

inflamed.

Speaker:

My HRV would tend

Speaker:

to drop,

Speaker:

et cetera.

Speaker:

Do you think that

Speaker:

there's a sort of

Speaker:

a direct, well,

Speaker:

that social

Speaker:

isolation is

Speaker:

going to fuel

Speaker:

that CDR1

Speaker:

response as well,

Speaker:

or at least as we

Speaker:

get older, is it

Speaker:

going to

Speaker:

exacerbate it?

Speaker:

I think it's a

Speaker:

question of

Speaker:

correlation,

Speaker:

perpetuating

Speaker:

causation.

Speaker:

So I don't think

Speaker:

it's causation,

Speaker:

and it's, I don't

Speaker:

think it's a

Speaker:

direct causation,

Speaker:

but I think it

Speaker:

most certainly

Speaker:

has a correlate

Speaker:

to perpetuating

Speaker:

this misaligned

Speaker:

immunological

Speaker:

expression.

Speaker:

So as you

Speaker:

mentioned before,

Speaker:

when you were

Speaker:

younger, being

Speaker:

able to be within

Speaker:

your own space

Speaker:

and be in a state

Speaker:

of, I won't say

Speaker:

isolation, but in

Speaker:

a solitary state,

Speaker:

a solitude, that

Speaker:

is solitude.

Speaker:

That's a better

Speaker:

way, because

Speaker:

isolation kind of

Speaker:

sounds like

Speaker:

you're

Speaker:

self-flagellating,

Speaker:

right?

Speaker:

But solitude

Speaker:

sounds a

Speaker:

lot better.

Speaker:

Yeah,

Speaker:

it's better.

Speaker:

So when you're

Speaker:

younger, you're

Speaker:

able to stay at a

Speaker:

state, well, you

Speaker:

may have been

Speaker:

able, not

Speaker:

everybody, but in

Speaker:

your case, you

Speaker:

may have stayed

Speaker:

at a state of

Speaker:

solitude, but yet

Speaker:

you're not

Speaker:

dealing with

Speaker:

spike protein.

Speaker:

You're not

Speaker:

dealing with

Speaker:

possible

Speaker:

associated

Speaker:

re-expressions of

Speaker:

envelope-based

Speaker:

viruses.

Speaker:

As you get older,

Speaker:

by way of being

Speaker:

exposed to heavy

Speaker:

metals, which we

Speaker:

all are, and a

Speaker:

patient asked me

Speaker:

the other day,

Speaker:

"Where did I have

Speaker:

exposure to heavy

Speaker:

metals?"

Speaker:

I'm like, "Where

Speaker:

did you not?"

Speaker:

Why do you not

Speaker:

have exposure to

Speaker:

heavy metals in

Speaker:

the day which we

Speaker:

live in?

Speaker:

They're

Speaker:

accumulates,

Speaker:

they're

Speaker:

accumulates.

Speaker:

So as we get

Speaker:

older, we

Speaker:

accumulate

Speaker:

toxins, the body

Speaker:

accumulates

Speaker:

toxins,

Speaker:

particularly if

Speaker:

we're not in the

Speaker:

nurse, how to

Speaker:

remove them, and

Speaker:

to have,

Speaker:

it's super

Speaker:

important to be

Speaker:

responsible, and

Speaker:

at word

Speaker:

responsible,

Speaker:

meaning the

Speaker:

ability to

Speaker:

respond to it in

Speaker:

today's

Speaker:

current times.

Speaker:

And what I'm

Speaker:

referring to here

Speaker:

is taking

Speaker:

strategies in and

Speaker:

into an habitual

Speaker:

aspect, affording

Speaker:

the body to be

Speaker:

lightened from

Speaker:

its environmental

Speaker:

toxin load.

Speaker:

Things like Epsom

Speaker:

salts, baths,

Speaker:

things like

Speaker:

sauna, okay?

Speaker:

And obviously, it

Speaker:

is also need to

Speaker:

come with certain

Speaker:

considerations,

Speaker:

not everybody

Speaker:

should be doing

Speaker:

them either.

Speaker:

That's why I'm

Speaker:

not making a

Speaker:

blanket statement

Speaker:

that sauna is the

Speaker:

holy grail for

Speaker:

everybody.

Speaker:

Some were to go

Speaker:

into a sauna,

Speaker:

particularly

Speaker:

those who have a

Speaker:

perpetuated

Speaker:

CDR1 state.

Speaker:

It's just going

Speaker:

to, it's going to

Speaker:

exacerbate your

Speaker:

muscle

Speaker:

response, okay?

Speaker:

So you need to

Speaker:

like, it's

Speaker:

contextual, but

Speaker:

regardless, those

Speaker:

are the instates.

Speaker:

When we get to

Speaker:

the point where

Speaker:

we become highly

Speaker:

reactive, we

Speaker:

wanna prevent

Speaker:

people from

Speaker:

getting to that

Speaker:

point, okay?

Speaker:

When you are at

Speaker:

that point, it is

Speaker:

likely that

Speaker:

you're gonna need

Speaker:

a practitioner

Speaker:

like myself or my

Speaker:

team to come in

Speaker:

and guide the

Speaker:

process because

Speaker:

it's complex,

Speaker:

it's very

Speaker:

complex.

Speaker:

But we don't want

Speaker:

you to get there.

Speaker:

Like, I don't

Speaker:

want to see a

Speaker:

billion people.

Speaker:

You know, I'd

Speaker:

rather see less

Speaker:

people, ill and

Speaker:

support more

Speaker:

people being

Speaker:

healthy.

Speaker:

Yeah,

Speaker:

preventative,

Speaker:

okay.

Speaker:

So habitual detox

Speaker:

needs to be part

Speaker:

of every modern

Speaker:

day man's

Speaker:

routine.

Speaker:

We do not, we're

Speaker:

not, the society

Speaker:

is not going to

Speaker:

reduce its toxic

Speaker:

assault on us.

Speaker:

So long as

Speaker:

technology

Speaker:

affords a payoff,

Speaker:

we're gonna

Speaker:

continue to have

Speaker:

more toxins.

Speaker:

Just make peace

Speaker:

with that.

Speaker:

Yes, I'm hopeful

Speaker:

that humanity's

Speaker:

future will

Speaker:

afford better

Speaker:

practices, but in

Speaker:

the meantime,

Speaker:

let's not negate

Speaker:

the reality of

Speaker:

corporations and

Speaker:

the effect that

Speaker:

they have on the

Speaker:

economy, okay?

Speaker:

And also that

Speaker:

effect in which

Speaker:

it has in

Speaker:

providing

Speaker:

employment across

Speaker:

the globe.

Speaker:

So we can't

Speaker:

discredit all

Speaker:

these things.

Speaker:

We have to

Speaker:

consider these

Speaker:

things, and which

Speaker:

means that we

Speaker:

need to be

Speaker:

malleable in what

Speaker:

it is that we

Speaker:

contribute to our

Speaker:

own health.

Speaker:

Bringing back

Speaker:

again the

Speaker:

community

Speaker:

consciousness

Speaker:

around

Speaker:

health, right?

Speaker:

Yeah, so now your

Speaker:

tolerance in that

Speaker:

isolated state in

Speaker:

contrast to when

Speaker:

you're younger is

Speaker:

also fueled not

Speaker:

only by the fact

Speaker:

that you should

Speaker:

be around people,

Speaker:

because obviously

Speaker:

your spirit is

Speaker:

telling you this

Speaker:

such, but it's

Speaker:

also fueled by

Speaker:

the fact that

Speaker:

there's certain

Speaker:

energetic bodies

Speaker:

that we exist

Speaker:

within, not only

Speaker:

the

Speaker:

physical state.

Speaker:

And I say that, I

Speaker:

think it was

Speaker:

Wayne Dyer that

Speaker:

mentioned one of

Speaker:

his audio books.

Speaker:

He had a friend

Speaker:

that was a

Speaker:

neurologist, and

Speaker:

they had to, he

Speaker:

went to his home

Speaker:

for dinner, and

Speaker:

they got into

Speaker:

conversation

Speaker:

about God, okay?

Speaker:

And obviously

Speaker:

that word has a

Speaker:

lot of meaning

Speaker:

for

Speaker:

different people,

Speaker:

or has meaning

Speaker:

for, yeah, has

Speaker:

difference of

Speaker:

meaning for

Speaker:

many people.

Speaker:

In any case, so

Speaker:

his friend was an

Speaker:

atheist, and he

Speaker:

said, "No, I

Speaker:

don't believe in

Speaker:

anything, "but I

Speaker:

cannot quantify."

Speaker:

See, so he's

Speaker:

like, "Okay, so

Speaker:

Tommy, "when you

Speaker:

open up a man's

Speaker:

brain, or the

Speaker:

skull, "when you

Speaker:

look into the

Speaker:

brain, "have you

Speaker:

ever witnessed

Speaker:

consciousness?"

Speaker:

That alone is

Speaker:

such a profound

Speaker:

realization, and

Speaker:

the entire human

Speaker:

body regenerates

Speaker:

itself every

Speaker:

seven, well, over

Speaker:

a period of

Speaker:

seven years.

Speaker:

Okay, so the

Speaker:

cellular

Speaker:

construct changes

Speaker:

every seven

Speaker:

years, and yet

Speaker:

consciousness--

Speaker:

Heart included.

Speaker:

Blooded.

Speaker:

Cardiac muscle

Speaker:

included?

Speaker:

Now you're asking

Speaker:

me a question, I

Speaker:

think so.

Speaker:

From my

Speaker:

understanding, I

Speaker:

think all cells

Speaker:

actually

Speaker:

recycle over a

Speaker:

period of

Speaker:

seven years.

Speaker:

Cardiac cells, I

Speaker:

think actually

Speaker:

have a quicker

Speaker:

recycling

Speaker:

capacity more so

Speaker:

than others.

Speaker:

Liver and cardiac

Speaker:

cells have

Speaker:

couldn't actually

Speaker:

repair quite

Speaker:

quickly,

Speaker:

but now you're

Speaker:

asking me, I need

Speaker:

to look back into

Speaker:

my physiology.

Speaker:

(Laughing) Yeah, no.

Speaker:

Don't remember

Speaker:

everything of

Speaker:

heart, but

Speaker:

nonetheless, all

Speaker:

cells, the

Speaker:

entire, like some

Speaker:

cells, like

Speaker:

they're repaired

Speaker:

slower than

Speaker:

others, but all

Speaker:

cells over a

Speaker:

seven year period

Speaker:

would have

Speaker:

changed, would

Speaker:

have actually

Speaker:

changed.

Speaker:

(Laughing) Would have been

Speaker:

recycled,

Speaker:

regenerated,

Speaker:

regenerated,

Speaker:

that's what I was

Speaker:

looking for,

Speaker:

regenerated.

Speaker:

So just have that

Speaker:

concept in your

Speaker:

mind, if your

Speaker:

entire construct

Speaker:

is gonna be

Speaker:

different in

Speaker:

seven years from

Speaker:

now, which it is,

Speaker:

but yet your

Speaker:

consciousness is

Speaker:

transferred

Speaker:

into your new

Speaker:

construct.

Speaker:

What does

Speaker:

that depict?

Speaker:

What does

Speaker:

that mean?

Speaker:

Does it mean that

Speaker:

Newtonian concept

Speaker:

of physical

Speaker:

reality of

Speaker:

physics is very

Speaker:

much a small

Speaker:

vantage point of

Speaker:

a greater

Speaker:

paradigm?

Speaker:

Are we looking

Speaker:

now to the realm

Speaker:

of quantum?

Speaker:

What are we, in

Speaker:

essence, in the

Speaker:

realm of quantum?

Speaker:

We're the space

Speaker:

between spaces.

Speaker:

What does

Speaker:

that mean?

Speaker:

We're a thought,

Speaker:

we're an idea.

Speaker:

And this is when

Speaker:

you start to

Speaker:

think of your, in

Speaker:

this type of

Speaker:

manner, and you

Speaker:

start to see a

Speaker:

human, not as a

Speaker:

physical body,

Speaker:

but as a spirit

Speaker:

having a human

Speaker:

experience, you

Speaker:

start to see that

Speaker:

the spirit comes

Speaker:

into experience

Speaker:

by way of its

Speaker:

desire of

Speaker:

education.

Speaker:

And it is

Speaker:

important that

Speaker:

when you start to

Speaker:

see a person

Speaker:

going through a

Speaker:

period of

Speaker:

struggle, that

Speaker:

you support their

Speaker:

education, that

Speaker:

you don't try to

Speaker:

have them avoid

Speaker:

their education,

Speaker:

which is where

Speaker:

opioids can come

Speaker:

into the equation

Speaker:

otherwise.

Speaker:

And I'm not

Speaker:

saying opioids

Speaker:

are always wrong,

Speaker:

there are

Speaker:

instances where

Speaker:

they're helpful,

Speaker:

but definitely

Speaker:

not to the degree

Speaker:

of which they're

Speaker:

being abused.

Speaker:

And this is where

Speaker:

the ego, now

Speaker:

we're going to

Speaker:

the realm of

Speaker:

psychology, has

Speaker:

the part in

Speaker:

trying to

Speaker:

captivate its

Speaker:

falsehood in

Speaker:

your belief

Speaker:

in being your

Speaker:

God, in being

Speaker:

your reality.

Speaker:

And in essence,

Speaker:

the ego is just a

Speaker:

program that we

Speaker:

adopt for

Speaker:

survival in the

Speaker:

physical

Speaker:

construct, but it

Speaker:

most certainly

Speaker:

does not need to

Speaker:

define us.

Speaker:

And when you

Speaker:

don't let it

Speaker:

define you,

Speaker:

because the ego

Speaker:

is also manifest

Speaker:

by cultural,

Speaker:

societal, and

Speaker:

belief

Speaker:

systems, right?

Speaker:

Which get

Speaker:

impressed upon us

Speaker:

from the day in

Speaker:

which we

Speaker:

were born.

Speaker:

So it begs the

Speaker:

question is what

Speaker:

is us and what

Speaker:

isn't us?

Speaker:

Like are we the

Speaker:

narrative that we

Speaker:

have adopted?

Speaker:

Are we more?

Speaker:

And I believe

Speaker:

that we're more,

Speaker:

I believe in the

Speaker:

latter, but it is

Speaker:

important to

Speaker:

nurse a person's

Speaker:

experience so

Speaker:

that they can

Speaker:

have the life of

Speaker:

an elevated life

Speaker:

where they're not

Speaker:

impacted by the

Speaker:

burden of disease

Speaker:

and so on, which

Speaker:

means that

Speaker:

sometimes when

Speaker:

somebody's going

Speaker:

through shit,

Speaker:

it's because they

Speaker:

are meant to go

Speaker:

through shit.

Speaker:

They're meant not

Speaker:

to just stay

Speaker:

there, but

Speaker:

they're meant to

Speaker:

go through it.

Speaker:

Now you can't go

Speaker:

through something

Speaker:

if you avoid it.

Speaker:

It's like having

Speaker:

a tunnel.

Speaker:

It's like you're

Speaker:

being on a main

Speaker:

road and there's

Speaker:

a tunnel

Speaker:

coming up.

Speaker:

And you gotta go

Speaker:

through the

Speaker:

tunnel to get to

Speaker:

the other side

Speaker:

and see the

Speaker:

daylight again.

Speaker:

But you get to

Speaker:

the tunnel and

Speaker:

instead of going

Speaker:

through the

Speaker:

tunnel, you just

Speaker:

put on all your

Speaker:

lights in the car

Speaker:

so that you could

Speaker:

have some light,

Speaker:

but you blind

Speaker:

yourself and then

Speaker:

you try to go

Speaker:

through the

Speaker:

tunnel, but you

Speaker:

keep on crashing

Speaker:

because you have

Speaker:

too much light

Speaker:

going on in your

Speaker:

car because

Speaker:

you're not

Speaker:

willing to

Speaker:

experience a

Speaker:

brevity of

Speaker:

darkness.

Speaker:

Yeah, that

Speaker:

makes sense.

Speaker:

I think that

Speaker:

there's a lot

Speaker:

there to unpack.

Speaker:

And yeah, it is

Speaker:

interesting how

Speaker:

we sort of

Speaker:

managed to link

Speaker:

CDR one up with

Speaker:

almost this sort

Speaker:

of pseudo concept

Speaker:

of free will.

Speaker:

I guess.

Speaker:

But yeah, getting

Speaker:

back to sort of

Speaker:

the cell danger

Speaker:

response just to

Speaker:

sort of tie up

Speaker:

this section of

Speaker:

the conversation.

Speaker:

CDR two

Speaker:

specifically, you

Speaker:

sort of

Speaker:

elucidated that

Speaker:

CDR one is where

Speaker:

there's a lot of

Speaker:

sort of disparity

Speaker:

in fuel sources

Speaker:

being used and

Speaker:

this cell becomes

Speaker:

sort of almost

Speaker:

more glycolytic

Speaker:

and sort of more

Speaker:

dependent on

Speaker:

those fuel

Speaker:

sources and less

Speaker:

able to maybe

Speaker:

utilize fatty

Speaker:

acids if you're,

Speaker:

which I think is

Speaker:

quite interesting

Speaker:

because you

Speaker:

oftentimes see

Speaker:

people who are

Speaker:

unable to fast,

Speaker:

unable to sort of

Speaker:

utilize ketogenic

Speaker:

diets

Speaker:

effectively.

Speaker:

They're often in

Speaker:

this state.

Speaker:

Now, it then

Speaker:

obviously

Speaker:

progresses as you

Speaker:

alluded

Speaker:

to CDR two.

Speaker:

Would you sort of

Speaker:

mind sort of

Speaker:

carrying on the

Speaker:

conversation

Speaker:

from there?

Speaker:

Yeah, absolutely.

Speaker:

So CDR two from a

Speaker:

pathological

Speaker:

perspective has

Speaker:

high association

Speaker:

with cancer and

Speaker:

PCOS and

Speaker:

endometriosis.

Speaker:

In essence, where

Speaker:

replication or

Speaker:

cell cycle arrest

Speaker:

starts to become

Speaker:

somewhat

Speaker:

compromised.

Speaker:

So CDR two is

Speaker:

when it is a

Speaker:

predominant mTOR

Speaker:

state and not

Speaker:

enough of an AMPK

Speaker:

reactive state.

Speaker:

So this is where

Speaker:

mitochondria

Speaker:

become highly

Speaker:

saturated.

Speaker:

Okay, so if one

Speaker:

is stuck in a CDR

Speaker:

two, let's

Speaker:

understand from

Speaker:

the natural way

Speaker:

in which this

Speaker:

whole sequence of

Speaker:

events is meant

Speaker:

to unfold is that

Speaker:

when you

Speaker:

initially have a

Speaker:

threat, you

Speaker:

induce

Speaker:

inflammation,

Speaker:

which by way of

Speaker:

increasing the

Speaker:

activity of

Speaker:

glycolysis,

Speaker:

you're gonna

Speaker:

increase

Speaker:

extracellular ATP

Speaker:

quite rapidly.

Speaker:

That

Speaker:

extracellular ATP

Speaker:

fills the

Speaker:

response of the

Speaker:

innate system,

Speaker:

but also then

Speaker:

triggers the

Speaker:

adaptive immune

Speaker:

system to create

Speaker:

replication,

Speaker:

plonal

Speaker:

replication,

Speaker:

okay.

Speaker:

And then you get

Speaker:

into the CDR two.

Speaker:

Now the CDR two,

Speaker:

you have again,

Speaker:

it's glycolysis

Speaker:

as well as your

Speaker:

oxidase or

Speaker:

phosphorylated

Speaker:

systems that

Speaker:

start to kick in.

Speaker:

But they kick in

Speaker:

in a more of a

Speaker:

predominance mTOR

Speaker:

fashion for

Speaker:

recovery, okay,

Speaker:

for recovery

Speaker:

because CDR one,

Speaker:

inflammation

Speaker:

damages tissue.

Speaker:

CDR two, the

Speaker:

recovery of that

Speaker:

damaged tissue

Speaker:

needs to take

Speaker:

place, okay.

Speaker:

And then CDR

Speaker:

three, if you're

Speaker:

there, this is

Speaker:

when you're

Speaker:

nucleotide, your

Speaker:

production of

Speaker:

NAD, FAD, this

Speaker:

starts to ramp up

Speaker:

to support

Speaker:

electron

Speaker:

transport chain.

Speaker:

Okay, but if you

Speaker:

get stuck in a

Speaker:

CDR three, it's

Speaker:

because there is

Speaker:

compromise in the

Speaker:

phosphate

Speaker:

systems.

Speaker:

Not to support

Speaker:

the electron

Speaker:

transport chain.

Speaker:

So this is

Speaker:

where like,

Speaker:

that autism is

Speaker:

indicative

Speaker:

of CDR three.

Speaker:

Okay, so you have

Speaker:

optimal oxidative

Speaker:

phosphorylation,

Speaker:

but you don't

Speaker:

have enough of

Speaker:

the spark because

Speaker:

your glycolysis

Speaker:

lights that

Speaker:

bonfire to keep

Speaker:

the mitochondria

Speaker:

in an anhydrous

Speaker:

state,

Speaker:

catabolic state.

Speaker:

If you don't have

Speaker:

enough of that

Speaker:

glycolytic

Speaker:

reaction

Speaker:

occurring, then

Speaker:

the mitochondria,

Speaker:

although their

Speaker:

nucleotide

Speaker:

reactions can be

Speaker:

optimal through

Speaker:

oxidative

Speaker:

phosphorylation,

Speaker:

subsequent

Speaker:

availability of

Speaker:

things like NAD

Speaker:

would be

Speaker:

massively

Speaker:

declined because

Speaker:

sequence of in

Speaker:

the production of

Speaker:

NAD is also

Speaker:

highly reliant on

Speaker:

glycolysis

Speaker:

as well.

Speaker:

And this is where

Speaker:

something like

Speaker:

the thylene blue

Speaker:

would come in as

Speaker:

an electron dolib

Speaker:

because it's

Speaker:

obviously able to

Speaker:

bypass some of

Speaker:

those complexes

Speaker:

that are being

Speaker:

blocked, is that

Speaker:

correct?

Speaker:

In part, yes, but

Speaker:

most certainly

Speaker:

the first and the

Speaker:

third complexes,

Speaker:

but it also can

Speaker:

come into

Speaker:

the CDR one.

Speaker:

Let me

Speaker:

explain why.

Speaker:

So the CDR one

Speaker:

will trigger a

Speaker:

macrophage to

Speaker:

induce a

Speaker:

hepcidin, an

Speaker:

increase of

Speaker:

hepcidin

Speaker:

activity, which

Speaker:

basically affords

Speaker:

their consumption

Speaker:

of iron, thereby

Speaker:

increasing their

Speaker:

nature from an

Speaker:

anti-inflammatory

Speaker:

state to a

Speaker:

radical state, in

Speaker:

perpetuating

Speaker:

their

Speaker:

pro-inflammatory

Speaker:

activity in the

Speaker:

body, which by

Speaker:

means of

Speaker:

increasing

Speaker:

attraction toward

Speaker:

a particular site

Speaker:

is highly

Speaker:

feasible and also

Speaker:

productive.

Speaker:

So the macrophage

Speaker:

in compromising,

Speaker:

so by

Speaker:

compromising

Speaker:

iron,

Speaker:

by creating an

Speaker:

excess of

Speaker:

extracellular

Speaker:

iron as well not

Speaker:

being made

Speaker:

available for the

Speaker:

health of red

Speaker:

blood cells and

Speaker:

so on, has a

Speaker:

negative knock-on

Speaker:

impact onto the

Speaker:

pentose phosphate

Speaker:

cycle, which also

Speaker:

has a depleto

Speaker:

factor on NADPH

Speaker:

availability.

Speaker:

So in these

Speaker:

instances, iron

Speaker:

is incredibly

Speaker:

important for

Speaker:

oxidative

Speaker:

phosphorylation,

Speaker:

incredibly,

Speaker:

particularly with

Speaker:

those particular

Speaker:

oxidative

Speaker:

phosphorylated

Speaker:

points,

Speaker:

those stages.

Speaker:

So methylene blue

Speaker:

comes into the

Speaker:

equation by

Speaker:

firstly reducing

Speaker:

the release of

Speaker:

hepcidin, also by

Speaker:

neutralizing the

Speaker:

reactivity of

Speaker:

these monocytes,

Speaker:

all the while

Speaker:

even in an

Speaker:

iron-depleted

Speaker:

state, which most

Speaker:

viral incidences

Speaker:

can actually

Speaker:

induce, it still

Speaker:

supports the

Speaker:

mechanisms of

Speaker:

which get shut

Speaker:

down when one

Speaker:

goes into a

Speaker:

predominant

Speaker:

glycolytic state.

Speaker:

So methylene blue

Speaker:

can, most

Speaker:

certainly, it's a

Speaker:

versatile

Speaker:

molecule that can

Speaker:

be utilized in

Speaker:

multiple CDR

Speaker:

states, but

Speaker:

specifically CDR1

Speaker:

and CDR3, it is

Speaker:

highly beneficial

Speaker:

to incorporate

Speaker:

its use.

Speaker:

Okay, and just

Speaker:

one follow-up

Speaker:

from that, and

Speaker:

I've just been

Speaker:

going through

Speaker:

this, trying to

Speaker:

understand this

Speaker:

concept of

Speaker:

ferroptosis,

Speaker:

sort of

Speaker:

pre-programmed,

Speaker:

form of

Speaker:

pre-programmed

Speaker:

cell death that

Speaker:

is driven by sort

Speaker:

of, I believe,

Speaker:

characterized by

Speaker:

iron-dependent

Speaker:

accumulation in

Speaker:

lipid peroxides.

Speaker:

Now,

Speaker:

loosely with

Speaker:

methylene blue,

Speaker:

and I'm just

Speaker:

trying to link

Speaker:

this together on

Speaker:

the fly here, so

Speaker:

I might be

Speaker:

completely

Speaker:

off base,

Speaker:

would you

Speaker:

potentially

Speaker:

utilize methylene

Speaker:

blue when there's

Speaker:

this sort of

Speaker:

heightened

Speaker:

presence of

Speaker:

ferroptosis?

Speaker:

Absolutely, it

Speaker:

would propensiate

Speaker:

it, for sure.

Speaker:

Actually, it

Speaker:

propensiates ever

Speaker:

more, so it

Speaker:

wouldn't

Speaker:

inhibit it.

Speaker:

It would actually

Speaker:

propensiate that

Speaker:

particular

Speaker:

activity of

Speaker:

ferroptosis, for sure.

Speaker:

Okay.

Speaker:

Yeah.

Speaker:

All right,

Speaker:

okay, good.

Speaker:

I'm glad I

Speaker:

vaguely got

Speaker:

something

Speaker:

right today.

Speaker:

Yep, we have to

Speaker:

ask stuff, what

Speaker:

is the process of

Speaker:

ferroptosis

Speaker:

actually

Speaker:

inducing?

Speaker:

A form of

Speaker:

apoptosis or a

Speaker:

necrosis.

Speaker:

Exactly,

Speaker:

apoptosis,

Speaker:

hopefully not

Speaker:

necrosis, but

Speaker:

apoptosis,

Speaker:

for sure.

Speaker:

And what

Speaker:

methylene blue

Speaker:

will actually do

Speaker:

is fuel that

Speaker:

process of

Speaker:

autophagy to

Speaker:

occur by way in

Speaker:

which it actually

Speaker:

modulates

Speaker:

oxidative

Speaker:

phosphorylated

Speaker:

pathways to

Speaker:

ensure the

Speaker:

continual supply

Speaker:

of energy that's

Speaker:

required during

Speaker:

processes of

Speaker:

autophagy.

Speaker:

Okay, I think

Speaker:

I've got that.

Speaker:

That's, yeah,

Speaker:

I've got it good.

Speaker:

If you think

Speaker:

about the

Speaker:

difference

Speaker:

between

Speaker:

catecholamine,

Speaker:

dorbicorticoids,

Speaker:

and

Speaker:

insulin, okay.

Speaker:

So insulin brings

Speaker:

things into the

Speaker:

cell,

Speaker:

dorbicorticoids,

Speaker:

catecholamine

Speaker:

release things

Speaker:

from the cell.

Speaker:

Okay, so when we

Speaker:

are looking to,

Speaker:

(Laughs)

Speaker:

I'm trying to

Speaker:

simplify

Speaker:

something very

Speaker:

complex.

Speaker:

(Laughs) Sorry, sorry,

Speaker:

this is

Speaker:

completely

Speaker:

my fault.

Speaker:

We've gone off on

Speaker:

a tangent.

Speaker:

No, not at all,

Speaker:

not at all.

Speaker:

When we are

Speaker:

looking to break

Speaker:

particles down,

Speaker:

we need somewhat

Speaker:

of a catalytic

Speaker:

reaction to

Speaker:

occur, okay.

Speaker:

In order for a

Speaker:

catalytic action

Speaker:

to occur, we need

Speaker:

availability

Speaker:

of ATP.

Speaker:

So we need to be able to do that

Speaker:

in the most

Speaker:

basic sense.

Speaker:

So in an increase

Speaker:

of ferroptosis,

Speaker:

you're most

Speaker:

certainly

Speaker:

inducing an

Speaker:

oxidative state

Speaker:

in the

Speaker:

body, okay.

Speaker:

That's pretty

Speaker:

much what it

Speaker:

does, and from

Speaker:

that, apoptosis

Speaker:

shouldn't ensue.

Speaker:

And high dose

Speaker:

vitamin C by way

Speaker:

is a way of

Speaker:

inducing

Speaker:

ferroptosis.

Speaker:

Yeah, that's one

Speaker:

of the, that's

Speaker:

one of, and

Speaker:

people didn't

Speaker:

realize this for

Speaker:

such a long time

Speaker:

when they were

Speaker:

like, you know,

Speaker:

using high dose

Speaker:

vitamin C and was

Speaker:

working

Speaker:

for cancer.

Speaker:

It's actually

Speaker:

because it

Speaker:

induces an

Speaker:

oxidative state

Speaker:

in order for the

Speaker:

body to

Speaker:

upregulate

Speaker:

certain regions

Speaker:

of lymphocyte

Speaker:

response.

Speaker:

This is why it

Speaker:

regenerates

Speaker:

lymphocytes.

Speaker:

Vitamin C is well

Speaker:

known to

Speaker:

regenerate such

Speaker:

toxic lymphocytes

Speaker:

that have become

Speaker:

exhausted, high

Speaker:

dose vitamin C.

Speaker:

And it's by way,

Speaker:

in part, by way

Speaker:

of this oxidative

Speaker:

process through

Speaker:

ferroptosis that

Speaker:

this occurs.

Speaker:

So in order for

Speaker:

this to continue

Speaker:

to provide

Speaker:

its process of

Speaker:

apoptosis

Speaker:

support, there is

Speaker:

a needed

Speaker:

availability of

Speaker:

energy that comes

Speaker:

into the

Speaker:

equation, not

Speaker:

only to fuel

Speaker:

this, but also to

Speaker:

mitigate the

Speaker:

excess of

Speaker:

radicals that can

Speaker:

also create an

Speaker:

unwanted effect

Speaker:

onto neighboring

Speaker:

tissues, which

Speaker:

whereby, if this

Speaker:

wasn't there, the

Speaker:

likelihood of

Speaker:

necrosis would be

Speaker:

a greater

Speaker:

probability.

Speaker:

So we don't want,

Speaker:

you know,

Speaker:

necrotic tissue

Speaker:

to accumulate.

Speaker:

We want the

Speaker:

breakdown and the

Speaker:

regeneration, the

Speaker:

optimal cell

Speaker:

cycle arrest or a

Speaker:

cyclo-renewal

Speaker:

state to come

Speaker:

into the, to into

Speaker:

expression.

Speaker:

This is where

Speaker:

methylene blue,

Speaker:

in specific

Speaker:

cases, most

Speaker:

certainly can

Speaker:

improve upon the

Speaker:

likelihood of

Speaker:

this actually

Speaker:

occurring.

Speaker:

The consideration

Speaker:

to methylene blue

Speaker:

is the

Speaker:

availability

Speaker:

to NADPH.

Speaker:

Okay.

Speaker:

If there is an

Speaker:

insufficient

Speaker:

availability of

Speaker:

NADPH, which is

Speaker:

predominantly

Speaker:

fueled through

Speaker:

the activity of

Speaker:

the

Speaker:

pentose-phosphate

Speaker:

pathway, then

Speaker:

you're going to

Speaker:

have an excess of

Speaker:

extracellular

Speaker:

methylene blue,

Speaker:

not leukolucalene

Speaker:

blue, but

Speaker:

extracellular

Speaker:

methylene blue

Speaker:

accumulate, which

Speaker:

again-- It's the

Speaker:

thiamine.

Speaker:

Yeah, the

Speaker:

thiamine, the

Speaker:

thiamine supports

Speaker:

the

Speaker:

pentose-phosphate

Speaker:

pathway.

Speaker:

There are other

Speaker:

elements that do

Speaker:

as well.

Speaker:

There are a lot,

Speaker:

but the thiamine,

Speaker:

as far as a focal

Speaker:

point is

Speaker:

concerned,

Speaker:

propensiates a

Speaker:

lot of the PPP

Speaker:

activity.

Speaker:

So in these

Speaker:

constructs

Speaker:

between the

Speaker:

pentose-phosphate

Speaker:

pathway NADPH,

Speaker:

NAD, when there

Speaker:

isn't enough

Speaker:

NADPH to

Speaker:

complement the

Speaker:

activity of NAD,

Speaker:

then leukocytes

Speaker:

lose their

Speaker:

capacity to

Speaker:

integrate from a

Speaker:

metabolomic level

Speaker:

methylene blue

Speaker:

into their

Speaker:

construct, which

Speaker:

is mostly the

Speaker:

reason as to

Speaker:

where, as a

Speaker:

dichromatic

Speaker:

material,

Speaker:

methylene blue

Speaker:

provides

Speaker:

antioxidant

Speaker:

support.

Speaker:

So it's both an

Speaker:

oxidative

Speaker:

potentiator as

Speaker:

well as an

Speaker:

antioxidant

Speaker:

potentiator.

Speaker:

And in order for

Speaker:

it to be

Speaker:

balanced, in

Speaker:

order for it to

Speaker:

have a modulated

Speaker:

effect on the

Speaker:

body, the

Speaker:

subsequent

Speaker:

availability of

Speaker:

NADPH is highly,

Speaker:

highly, highly

Speaker:

important.

Speaker:

And this is

Speaker:

something like

Speaker:

anybody that's

Speaker:

going through

Speaker:

like CDO1 or

Speaker:

CDO3, that's

Speaker:

looking to, considering

Speaker:

utilizing

Speaker:

methylene blue,

Speaker:

really first

Speaker:

thing is to look

Speaker:

into the state of

Speaker:

their spleen,

Speaker:

their specific

Speaker:

markers that can

Speaker:

give you

Speaker:

indication of

Speaker:

that MPV, ESR.

Speaker:

When there's

Speaker:

instance of

Speaker:

splenic

Speaker:

insufficiency,

Speaker:

first, make sure

Speaker:

that at the same

Speaker:

time that you are

Speaker:

supplementing

Speaker:

with methylene

Speaker:

blue, that you're

Speaker:

supporting the

Speaker:

PPP with

Speaker:

necessary

Speaker:

co-factors.

Speaker:

And then this

Speaker:

will help to

Speaker:

mitigate the

Speaker:

likelihood of

Speaker:

unwanted side

Speaker:

effect through

Speaker:

the use of

Speaker:

methylene blue.

Speaker:

It's the same

Speaker:

thing with ozone

Speaker:

therapy.

Speaker:

Ozone therapy is

Speaker:

incredible.

Speaker:

It most

Speaker:

certainly, I

Speaker:

mean, it does so

Speaker:

many things.

Speaker:

I'm just trying

Speaker:

to say

Speaker:

what it does.

Speaker:

It's like, I will

Speaker:

take another

Speaker:

podcast.

Speaker:

Yet, if you were

Speaker:

to administer

Speaker:

ozone therapy,

Speaker:

eventually, I

Speaker:

mean, there are

Speaker:

certain instances

Speaker:

where it requires

Speaker:

more application,

Speaker:

like for example,

Speaker:

Lyme disease

Speaker:

and cancer.

Speaker:

But that's also

Speaker:

because the

Speaker:

metabolic state

Speaker:

thus deems its

Speaker:

necessity based

Speaker:

upon what these

Speaker:

particular

Speaker:

constructs do to

Speaker:

immunomatabolism.

Speaker:

In situations

Speaker:

outside of that

Speaker:

construct, if you

Speaker:

were to use ozone

Speaker:

therapy every

Speaker:

day, it's not

Speaker:

gonna be very

Speaker:

healthy for you.

Speaker:

It's the same

Speaker:

with

Speaker:

methylene blue.

Speaker:

Same with

Speaker:

methylene blue.

Speaker:

It most certainly

Speaker:

can be utilized

Speaker:

on a daily basis

Speaker:

depending upon

Speaker:

the content,

Speaker:

sorry, the

Speaker:

context, the

Speaker:

context as to

Speaker:

where you're

Speaker:

using the

Speaker:

methylene blue

Speaker:

content

Speaker:

within, right?

Speaker:

So I'm going off

Speaker:

on the tangent of

Speaker:

methylene blue,

Speaker:

but it does bring

Speaker:

you to what it

Speaker:

was talking

Speaker:

about,

Speaker:

immunomatabolism

Speaker:

and dichromatic

Speaker:

materials.

Speaker:

Kirkman is

Speaker:

another

Speaker:

dichromatic

Speaker:

material, by the

Speaker:

way, but also

Speaker:

plays incredible

Speaker:

vantage role in

Speaker:

mitigating

Speaker:

astrogliosis in

Speaker:

the brain,

Speaker:

thus reducing the

Speaker:

potential buildup

Speaker:

of amyloid

Speaker:

plaques as well

Speaker:

as modulating

Speaker:

cineclic protein,

Speaker:

ensuring that the

Speaker:

misfolding of

Speaker:

those proteins

Speaker:

don't ensue

Speaker:

within the

Speaker:

certain regions

Speaker:

of the brain.

Speaker:

So these are all,

Speaker:

these dichromatic

Speaker:

materials are

Speaker:

credible, but too

Speaker:

much Kirkman in

Speaker:

certain

Speaker:

individuals that

Speaker:

have compromised

Speaker:

in their modamine

Speaker:

oxidase activity

Speaker:

or in their

Speaker:

phenol breakdown,

Speaker:

which has a lot

Speaker:

to do actually

Speaker:

with gluten

Speaker:

intolerance.

Speaker:

So those who have

Speaker:

like severe

Speaker:

gluten

Speaker:

intolerance, if

Speaker:

you give them a

Speaker:

high dose of

Speaker:

Kirkman, there's

Speaker:

a likelihood that

Speaker:

the phenol load

Speaker:

in the Kirkman

Speaker:

may cause

Speaker:

anxiety.

Speaker:

Just on Kirkman

Speaker:

quickly, have you

Speaker:

ever seen any

Speaker:

issues,

Speaker:

particularly with

Speaker:

Kirkman and

Speaker:

overly inhibiting

Speaker:

5-alpha

Speaker:

reductase?

Speaker:

Obviously that's

Speaker:

another tangent

Speaker:

of the rabbit

Speaker:

hole, but some

Speaker:

people are going

Speaker:

to be more

Speaker:

sensitive to the

Speaker:

inhibition of

Speaker:

that enzyme than

Speaker:

say others.

Speaker:

Do you think, and

Speaker:

the whole

Speaker:

post-menastride

Speaker:

argument is a

Speaker:

completely

Speaker:

different

Speaker:

conversation, I

Speaker:

apologize to the

Speaker:

audience because

Speaker:

we've now gone on

Speaker:

rabbit holes, but

Speaker:

rabbit holes.

Speaker:

However, do you

Speaker:

think

Speaker:

some of these

Speaker:

nutrients to call

Speaker:

compounds,

Speaker:

high dose

Speaker:

riboflavin, zinc,

Speaker:

et cetera, what

Speaker:

are the other

Speaker:

ones, the lion's

Speaker:

mane, can

Speaker:

potentiate some

Speaker:

of these issues

Speaker:

that the same

Speaker:

class of drug

Speaker:

acting on the

Speaker:

same receptor

Speaker:

can, or do you

Speaker:

not see that to

Speaker:

be an issue

Speaker:

clinically

Speaker:

speaking?

Speaker:

I guess the

Speaker:

Kirkman,

Speaker:

resveratrol,

Speaker:

there are a

Speaker:

couple of others

Speaker:

that have an

Speaker:

impact on 5-alpha

Speaker:

reductase.

Speaker:

Some have also

Speaker:

reported that it

Speaker:

can have an

Speaker:

impact on free

Speaker:

androgen levels

Speaker:

as well in that

Speaker:

activity.

Speaker:

When you look

Speaker:

into the pharma

Speaker:

dynamics,

Speaker:

you'll see that

Speaker:

it really is

Speaker:

dependent upon

Speaker:

specific genetic

Speaker:

probabilities

Speaker:

into enzyme

Speaker:

function as to

Speaker:

how the person

Speaker:

breaks down these

Speaker:

particular

Speaker:

molecules, which

Speaker:

is quite

Speaker:

interesting

Speaker:

because those who

Speaker:

have a propensity

Speaker:

for a slower

Speaker:

caffeine

Speaker:

metabolism as an

Speaker:

example, which

Speaker:

also has certain

Speaker:

similarity of

Speaker:

enzymatic

Speaker:

interaction as to

Speaker:

how the liver

Speaker:

breaks down

Speaker:

Kirkman or

Speaker:

resveratrol.

Speaker:

In these

Speaker:

instances, these

Speaker:

people also have

Speaker:

a greater

Speaker:

tendency for

Speaker:

estrogen

Speaker:

dominance, not

Speaker:

always, but they

Speaker:

generally have,

Speaker:

sorry, they often

Speaker:

have a propensity

Speaker:

for more estrogen

Speaker:

dominance.

Speaker:

So it begs the

Speaker:

question of

Speaker:

what's going on

Speaker:

within certain

Speaker:

methylation

Speaker:

sequences

Speaker:

depending upon

Speaker:

the individual,

Speaker:

and as to what

Speaker:

impact this is

Speaker:

having on

Speaker:

modification

Speaker:

rates and the

Speaker:

different

Speaker:

modification

Speaker:

rates as well.

Speaker:

So it's

Speaker:

contextual, and

Speaker:

this is where the

Speaker:

incorporation of

Speaker:

inductive

Speaker:

reasoning is

Speaker:

highly, highly

Speaker:

important because

Speaker:

when we take a

Speaker:

deductive

Speaker:

paradigm,

Speaker:

Kirkman's great

Speaker:

for everybody.

Speaker:

Let's see, is it

Speaker:

for neural

Speaker:

formation?

Speaker:

Well, no, it

Speaker:

might be good for

Speaker:

a lot because

Speaker:

even in

Speaker:

longitudinal

Speaker:

studies, the

Speaker:

majority of

Speaker:

people had to

Speaker:

respond

Speaker:

positively to

Speaker:

Kirkman, but the

Speaker:

majority is not

Speaker:

everyone.

Speaker:

So you can't make

Speaker:

this definitive

Speaker:

statement and a

Speaker:

blanket statement

Speaker:

saying, "You

Speaker:

know, Kirkman,

Speaker:

you're good for

Speaker:

everybody."

Speaker:

And it can

Speaker:

actually backfire

Speaker:

because in

Speaker:

Kirkman's

Speaker:

activity in

Speaker:

mitigating

Speaker:

astrogliosis,

Speaker:

as well as

Speaker:

expressing more

Speaker:

sirtuin activity,

Speaker:

there are many

Speaker:

things as to what

Speaker:

kookanoids do in

Speaker:

the body and for

Speaker:

the

Speaker:

immune system.

Speaker:

One of the things

Speaker:

in which it does

Speaker:

is also inhibit

Speaker:

C-X-C-L

Speaker:

complexes, C-C-L

Speaker:

complexes,

Speaker:

which are also

Speaker:

sort of chemokine

Speaker:

subsets within

Speaker:

the immune

Speaker:

system itself.

Speaker:

And in doing so,

Speaker:

it can actually

Speaker:

reduce this

Speaker:

auto-reactivity

Speaker:

of monocytes that

Speaker:

I spoke about

Speaker:

before in the way

Speaker:

in which they

Speaker:

hijack our iron,

Speaker:

thereby becoming

Speaker:

super-sproxidated

Speaker:

radicals.

Speaker:

So Kirkman can

Speaker:

actually mitigate

Speaker:

that from

Speaker:

happening, but in

Speaker:

instances whereby

Speaker:

it can compromise

Speaker:

through the

Speaker:

antigen to

Speaker:

estrogen ratio

Speaker:

availability, and

Speaker:

this is very

Speaker:

much, it's not

Speaker:

the, I just have

Speaker:

to make this

Speaker:

statement, is

Speaker:

that we're not

Speaker:

dealing with a

Speaker:

majority here.

Speaker:

In this

Speaker:

statement, we are

Speaker:

dealing with

Speaker:

outliers, but

Speaker:

outliers

Speaker:

also matter.

Speaker:

So generally,

Speaker:

most people

Speaker:

respond very well

Speaker:

to Kirkman and it

Speaker:

helps immune

Speaker:

system

Speaker:

multi-levels, but

Speaker:

those whom do

Speaker:

have a disparity

Speaker:

or do develop a

Speaker:

disparity in the

Speaker:

ratio between

Speaker:

testosterone and

Speaker:

estrogen

Speaker:

through its use

Speaker:

can also actually

Speaker:

thereby

Speaker:

propensiate more

Speaker:

histamine release

Speaker:

because estrogen

Speaker:

out of all our

Speaker:

sex hormones is

Speaker:

the hormone that

Speaker:

propensiates

Speaker:

histamine release

Speaker:

more so than any

Speaker:

other hormone.

Speaker:

And this is also

Speaker:

a reason why

Speaker:

estrogen is more,

Speaker:

I don't like to

Speaker:

use the word

Speaker:

important,

Speaker:

has more of an

Speaker:

active role,

Speaker:

there we go.

Speaker:

You can see I

Speaker:

don't like

Speaker:

hierarchy.

Speaker:

(Laughs)

Speaker:

I try to avoid

Speaker:

these words at

Speaker:

all costs.

Speaker:

It's good, it

Speaker:

challenges my

Speaker:

vocabulary.

Speaker:

So it has more of

Speaker:

an active role in

Speaker:

modulating one's

Speaker:

libido, more so

Speaker:

in testosterone,

Speaker:

because people

Speaker:

aren't

Speaker:

aware of this.

Speaker:

Most people think

Speaker:

testosterone is

Speaker:

the hormone that

Speaker:

actually is

Speaker:

estrogen.

Speaker:

And the reason is

Speaker:

to, one of the

Speaker:

reasons as to why

Speaker:

estrogen, it

Speaker:

propensiates

Speaker:

histamine

Speaker:

receptors

Speaker:

in the brain

Speaker:

by way of its

Speaker:

impact in causing

Speaker:

the release of

Speaker:

histamine,

Speaker:

propensiating the

Speaker:

release of

Speaker:

histamine

Speaker:

as well.

Speaker:

So if you are in

Speaker:

a CDR1 state and

Speaker:

you histamine

Speaker:

prone, which is

Speaker:

what CH2

Speaker:

dominance, and

Speaker:

there are

Speaker:

multiple

Speaker:

contributory

Speaker:

factors that can

Speaker:

actually reduce a

Speaker:

CH2 dominant

Speaker:

state or CDR1

Speaker:

state, which

Speaker:

we'll go to

Speaker:

in a moment.

Speaker:

But if you are in

Speaker:

the state, you

Speaker:

really wanna take

Speaker:

as much

Speaker:

precaution

Speaker:

within avoiding

Speaker:

an estrogen

Speaker:

dominant state.

Speaker:

Because that

Speaker:

estrogen

Speaker:

dominance can

Speaker:

actually just

Speaker:

fuel more of the

Speaker:

histamine

Speaker:

activity and

Speaker:

histamine

Speaker:

dominance, and

Speaker:

thereby impact

Speaker:

other subsequent

Speaker:

endocrine

Speaker:

systems, such as

Speaker:

the thyroid

Speaker:

mitochondrial

Speaker:

axis as well.

Speaker:

So yeah, again,

Speaker:

this contextual,

Speaker:

the particular

Speaker:

genome in

Speaker:

question, or the

Speaker:

CYP enzyme in

Speaker:

question.

Speaker:

1A2.

Speaker:

Yes, correct,

Speaker:

correct.

Speaker:

Yeah, Justin,

Speaker:

that was again,

Speaker:

amazing.

Speaker:

I think we're

Speaker:

definitely gonna

Speaker:

have to have part

Speaker:

one, two, and

Speaker:

potentially three

Speaker:

to this podcast,

Speaker:

but it's been an

Speaker:

incredible

Speaker:

conversation so

Speaker:

far, thank you.

Speaker:

You're welcome.

Speaker:

Okay, I think

Speaker:

that really wraps

Speaker:

up this whole

Speaker:

concept of

Speaker:

immunomentabolism.

Speaker:

And again, I

Speaker:

apologize to the

Speaker:

audience.

Speaker:

We went on an

Speaker:

unknown number of

Speaker:

tangents, but I

Speaker:

hope it's of some

Speaker:

value to you.

Speaker:

And in any case,

Speaker:

it's definitely

Speaker:

been a

Speaker:

treat for me.

Speaker:

Maybe this is

Speaker:

just a selfish

Speaker:

reason to

Speaker:

podcast.

Speaker:

I don't know that

Speaker:

I've loved this.

Speaker:

Well, happy

Speaker:

to oblige.

Speaker:

It's been an

Speaker:

awesome

Speaker:

opportunity to be

Speaker:

able to have

Speaker:

reciprocity of

Speaker:

knowledge share,

Speaker:

within

Speaker:

knowledge share.

Speaker:

Well, I was about

Speaker:

to say, you're

Speaker:

too kind, and

Speaker:

we'll discuss

Speaker:

that later.

Speaker:

Anyway,

Speaker:

so upstream of

Speaker:

what causes this

Speaker:

dysfunction, you

Speaker:

obviously have

Speaker:

various systems.

Speaker:

And I think the

Speaker:

two I'd like to

Speaker:

maybe touch on

Speaker:

are the gut,

Speaker:

because I think

Speaker:

it's relatable

Speaker:

too for most of

Speaker:

the audience,

Speaker:

especially people

Speaker:

coming from this

Speaker:

from a

Speaker:

traditional

Speaker:

functional

Speaker:

medicine

Speaker:

standpoint,

Speaker:

should we say.

Speaker:

I mean, most

Speaker:

people view gut

Speaker:

dysfunction from

Speaker:

the point of

Speaker:

lipopolysaccharide

Speaker:

ingress, or these

Speaker:

so-called

Speaker:

endotoxins that

Speaker:

create this

Speaker:

phenomenon called

Speaker:

leaky gut.

Speaker:

Actually, I

Speaker:

almost got that

Speaker:

word right.

Speaker:

On test on

Speaker:

permeability,

Speaker:

whereby these

Speaker:

foreign

Speaker:

molecules, just

Speaker:

broadly speaking,

Speaker:

get into

Speaker:

circulation

Speaker:

through the

Speaker:

smaller intestine

Speaker:

and drive a lot

Speaker:

of inflammation.

Speaker:

Now, there's a

Speaker:

lot more

Speaker:

biochemistry

Speaker:

there, obviously,

Speaker:

and that's going

Speaker:

to sort of

Speaker:

subsequently

Speaker:

drive a lot of,

Speaker:

as you alluded to

Speaker:

earlier, HPA-axis

Speaker:

dysfunction,

Speaker:

which is then

Speaker:

going to have

Speaker:

this downstream

Speaker:

consequence on

Speaker:

the immune

Speaker:

system, or

Speaker:

potentially

Speaker:

vice versa.

Speaker:

I think you could

Speaker:

definitely

Speaker:

explain this

Speaker:

better than I

Speaker:

could, but would

Speaker:

you mind just

Speaker:

maybe talking us

Speaker:

through why this

Speaker:

potentially can start off in the

Speaker:

gut, this sort of

Speaker:

immune

Speaker:

dysfunction,

Speaker:

this cell danger

Speaker:

response?

Speaker:

And then maybe we

Speaker:

could also then

Speaker:

wrap it up with a

Speaker:

short

Speaker:

conversation

Speaker:

about it from an

Speaker:

autonomic nervous

Speaker:

system

Speaker:

standpoint, too.

Speaker:

But yeah, we

Speaker:

could start there

Speaker:

and then go on.

Speaker:

That would

Speaker:

be great.

Speaker:

Absolutely,

Speaker:

absolutely.

Speaker:

It's interesting

Speaker:

to see the

Speaker:

microbiome profiling

Speaker:

dependent upon

Speaker:

the different

Speaker:

stages of one's

Speaker:

life and the

Speaker:

predominance of

Speaker:

different

Speaker:

species.

Speaker:

It's even more

Speaker:

interesting when

Speaker:

you overlay that

Speaker:

mapping as to

Speaker:

what particular

Speaker:

species ought to

Speaker:

be dominant in

Speaker:

contrast to those

Speaker:

who may be

Speaker:

dominant into

Speaker:

certain lifestyle

Speaker:

factors as well.

Speaker:

And I'm not just

Speaker:

talking about

Speaker:

blatant

Speaker:

infarctions.

Speaker:

I'm talking about

Speaker:

the subtle

Speaker:

infarctions.

Speaker:

For example,

Speaker:

going through a

Speaker:

bereavement.

Speaker:

Going through a

Speaker:

bereavement most

Speaker:

certainly has an

Speaker:

impact on the

Speaker:

limbic system

Speaker:

subsequently

Speaker:

impacts the

Speaker:

gastrointestinal

Speaker:

endocrine system,

Speaker:

affording

Speaker:

opportunity of

Speaker:

change of pH

Speaker:

variables.

Speaker:

And as you

Speaker:

alluded to

Speaker:

alluded, well,

Speaker:

alluded to

Speaker:

before, I love

Speaker:

the subtle

Speaker:

differences of

Speaker:

the difference of

Speaker:

meaning between

Speaker:

words, but as you

Speaker:

alluded to before

Speaker:

lipopolysaccharides,

Speaker:

I actually just

Speaker:

finished the

Speaker:

dissertation a

Speaker:

few years back on

Speaker:

lipopolysaccharides

Speaker:

and the impact

Speaker:

that they have on

Speaker:

major depressive

Speaker:

disorder.

Speaker:

But in my

Speaker:

research, there

Speaker:

are multiple

Speaker:

different

Speaker:

mechanisms

Speaker:

in which it

Speaker:

induced

Speaker:

neurodiversity.

Speaker:

And again, the

Speaker:

reason why I

Speaker:

bring up

Speaker:

neurodiversity,

Speaker:

histamine

Speaker:

dominance, CDR1,

Speaker:

and its impact on

Speaker:

depleting methyl

Speaker:

donors as well as

Speaker:

availability of

Speaker:

iron, it's very,

Speaker:

very apparent.

Speaker:

And if you don't

Speaker:

have these

Speaker:

precursors

Speaker:

available,

Speaker:

they're looking

Speaker:

at HVA levels,

Speaker:

looking at 5HIA

Speaker:

levels, looking

Speaker:

at VMA levels.

Speaker:

These are all

Speaker:

subsequently

Speaker:

always impaired

Speaker:

in those who have

Speaker:

TH2 dominance, or

Speaker:

at least

Speaker:

one of them.

Speaker:

Those are all

Speaker:

organic acids for

Speaker:

the

Speaker:

autososaccharide.

Speaker:

Correct, yeah, so

Speaker:

your 5HA is an

Speaker:

organic acid

Speaker:

marker depicting

Speaker:

activity of

Speaker:

serotonin,

Speaker:

which if it's too

Speaker:

high, it's also a

Speaker:

problem because

Speaker:

you might have an

Speaker:

excess of

Speaker:

peripheral

Speaker:

serotonin, which

Speaker:

by its nature can

Speaker:

certainly induce

Speaker:

peripheral, it

Speaker:

fuel peripheral

Speaker:

inflammation.

Speaker:

I mean parasites

Speaker:

feed off of

Speaker:

serotonin.

Speaker:

There's a reason

Speaker:

as to why we have

Speaker:

more parasitic

Speaker:

activity during

Speaker:

the full moon,

Speaker:

because there's a

Speaker:

compromise in

Speaker:

terms of the

Speaker:

serotonin being

Speaker:

methylated into

Speaker:

melatonin during

Speaker:

that time.

Speaker:

Because this is

Speaker:

why a lot of

Speaker:

your, again, this

Speaker:

is also based

Speaker:

upon some

Speaker:

science, but also

Speaker:

functional

Speaker:

paradigm science,

Speaker:

which it's like

Speaker:

the

Speaker:

metaphysicians

Speaker:

have been

Speaker:

alluding to

Speaker:

quantum physics

Speaker:

well before the

Speaker:

scientists jump

Speaker:

on board and then

Speaker:

they

Speaker:

figure it out.

Speaker:

So there is some

Speaker:

association, but

Speaker:

anyway, going

Speaker:

back to 5HA,

Speaker:

there's an

Speaker:

association with

Speaker:

serotonin, too

Speaker:

much, really bad,

Speaker:

too little, also,

Speaker:

it's a question

Speaker:

of balance.

Speaker:

And then your HVA

Speaker:

is your

Speaker:

homo-banylic

Speaker:

acid, which is an

Speaker:

indication of

Speaker:

dopamine

Speaker:

activity.

Speaker:

And you've got

Speaker:

Dokpak as well,

Speaker:

precursor.

Speaker:

And then you've

Speaker:

got your VMA,

Speaker:

which is an

Speaker:

indication of

Speaker:

nwopin, a front

Speaker:

end of the thing.

Speaker:

So there are

Speaker:

certain nutrient

Speaker:

donors required

Speaker:

for these

Speaker:

enzymatic

Speaker:

reactions to

Speaker:

take place.

Speaker:

Like for example,

Speaker:

the production of

Speaker:

dopamine, all

Speaker:

dopamine,

Speaker:

dopamine, and

Speaker:

what that

Speaker:

requires from the

Speaker:

pateratin cycle

Speaker:

as an

Speaker:

example, right?

Speaker:

And what impact

Speaker:

that pateratin

Speaker:

cycle has on the

Speaker:

folate pathway in

Speaker:

relation to

Speaker:

acetylsomatini

Speaker:

and homocysteine.

Speaker:

So there's an

Speaker:

interplay in this

Speaker:

whole makeup, but

Speaker:

essence of CDR1,

Speaker:

it creates a

Speaker:

compromise to

Speaker:

that methylation

Speaker:

cycling, those

Speaker:

methylation

Speaker:

wheels, because

Speaker:

of the state of

Speaker:

our chronic load

Speaker:

rate information

Speaker:

causing that

Speaker:

compromise in the

Speaker:

first place.

Speaker:

So when we look

Speaker:

into the gut in

Speaker:

particular,

Speaker:

and we see the

Speaker:

impact that

Speaker:

lipopolysaccharides

Speaker:

or the impact

Speaker:

that stress can

Speaker:

have an impact on

Speaker:

the gut affording

Speaker:

opportunity to

Speaker:

lipopolysaccharides

Speaker:

come through, we

Speaker:

often notice a

Speaker:

decrease of

Speaker:

neurotransmitters

Speaker:

or availability

Speaker:

of

Speaker:

neurotransmitters

Speaker:

and an expression

Speaker:

of cytokines.

Speaker:

And also

Speaker:

morphological

Speaker:

changes that

Speaker:

occur in the

Speaker:

brain themselves.

Speaker:

So the

Speaker:

morphological

Speaker:

changes are more

Speaker:

likely to occur

Speaker:

in a perpetuated

Speaker:

state of CDR1 or

Speaker:

TH2 dominance, or

Speaker:

particularly in

Speaker:

the developmental

Speaker:

stages of an

Speaker:

infant's life,

Speaker:

kind of the first

Speaker:

seven

Speaker:

years of life.

Speaker:

So this is why

Speaker:

even in the

Speaker:

uterine

Speaker:

considerations of

Speaker:

the mother's

Speaker:

stress state is

Speaker:

highly important

Speaker:

to take into

Speaker:

consideration.

Speaker:

Too much cortisol

Speaker:

can actually

Speaker:

cause the

Speaker:

depletion of

Speaker:

certain enzymes

Speaker:

that are within

Speaker:

the placenta that

Speaker:

are meant to be

Speaker:

able to contend

Speaker:

with that for

Speaker:

immunological

Speaker:

purposes, thereby

Speaker:

actually

Speaker:

resulting in an

Speaker:

increase of the

Speaker:

exposure to the

Speaker:

fetus developing

Speaker:

brain to

Speaker:

cortisol, thereby

Speaker:

actually creating

Speaker:

morphological

Speaker:

changes before

Speaker:

the baby's

Speaker:

even born.

Speaker:

So the reason why

Speaker:

I'm bringing up

Speaker:

like intrauterine

Speaker:

activity and

Speaker:

reason why it was

Speaker:

regards to the

Speaker:

gut is because

Speaker:

it's all

Speaker:

interconnected.

Speaker:

You know, if

Speaker:

there's an

Speaker:

imbalance of

Speaker:

perception, which

Speaker:

by way of

Speaker:

depletion of

Speaker:

certain

Speaker:

neurotransmitters

Speaker:

that can be

Speaker:

induced, that

Speaker:

subsequent

Speaker:

imbalance is also

Speaker:

gonna create

Speaker:

somewhat of a

Speaker:

threat

Speaker:

perception.

Speaker:

Now, if the

Speaker:

body's in a state

Speaker:

of threat

Speaker:

perception, as in

Speaker:

these monocytes

Speaker:

being

Speaker:

professionally

Speaker:

activated, to try

Speaker:

and re-inoculate

Speaker:

the body is

Speaker:

incredibly

Speaker:

difficult.

Speaker:

You can probably

Speaker:

take all the

Speaker:

probiotics

Speaker:

in the world.

Speaker:

I even had

Speaker:

patients of mine

Speaker:

whom decided to

Speaker:

take on the

Speaker:

advice of doctors

Speaker:

that have been

Speaker:

around for a lot

Speaker:

longer

Speaker:

than I had.

Speaker:

And I had good

Speaker:

intentions in

Speaker:

these doctors,

Speaker:

but they didn't

Speaker:

see this

Speaker:

particular

Speaker:

sequence of--

Speaker:

Phenotab.

Speaker:

Yeah, they didn't

Speaker:

see this paradigm

Speaker:

for what it was,

Speaker:

so they couldn't

Speaker:

conceptualize

Speaker:

what this

Speaker:

paradigm meant in

Speaker:

their efforts.

Speaker:

So anyway, these

Speaker:

patients spent a

Speaker:

lot of money on

Speaker:

fecal matter

Speaker:

transplant.

Speaker:

I'm talking a lot

Speaker:

of money.

Speaker:

If anybody knows

Speaker:

what FMT is, you

Speaker:

know, it's not a

Speaker:

cheap affair,

Speaker:

especially when

Speaker:

you're doing it

Speaker:

in a clinic,

Speaker:

but one of

Speaker:

which-- I was

Speaker:

about to say, I

Speaker:

think most

Speaker:

people, there are

Speaker:

lots of people,

Speaker:

well, not a lot,

Speaker:

but I know a few

Speaker:

people who sort

Speaker:

of go on the DIY

Speaker:

route, one might

Speaker:

say, and it's not

Speaker:

ended, maybe it's

Speaker:

a poor pun, but

Speaker:

it has not ended

Speaker:

up to be a very

Speaker:

pretty, with a

Speaker:

very

Speaker:

pretty ending.

Speaker:

So yeah, it's a

Speaker:

complete

Speaker:

different

Speaker:

wheelhouse, as

Speaker:

far as I'm

Speaker:

concerned.

Speaker:

I wouldn't go

Speaker:

anywhere near an

Speaker:

FMT without very

Speaker:

strict

Speaker:

supervision.

Speaker:

Yeah, you know, I

Speaker:

definitely want

Speaker:

to do it in a

Speaker:

clinic setting.

Speaker:

I think there are

Speaker:

suppositories and

Speaker:

what have that,

Speaker:

they're selling

Speaker:

at-home kits.

Speaker:

The thing is,

Speaker:

it's not about

Speaker:

just giving the

Speaker:

bacteria, whether

Speaker:

or not the body

Speaker:

receives it.

Speaker:

It's like trying

Speaker:

to give an organ

Speaker:

transplant to a

Speaker:

donor that

Speaker:

doesn't

Speaker:

match the donor.

Speaker:

Sorry, to a

Speaker:

recipient that

Speaker:

doesn't

Speaker:

match the donor.

Speaker:

So what we need

Speaker:

to do, if you

Speaker:

just take that

Speaker:

comparative

Speaker:

situation in

Speaker:

terms of the

Speaker:

organ donor, and

Speaker:

the organ

Speaker:

recipient

Speaker:

of the donor,

Speaker:

we need to

Speaker:

improve upon the

Speaker:

receptivity of

Speaker:

re-inoculation, in

Speaker:

re-inoculation.

Speaker:

So in order for

Speaker:

probiotics to

Speaker:

improve upon the

Speaker:

microbiome, the

Speaker:

immune system

Speaker:

needs to be in a

Speaker:

state of

Speaker:

coherence,

Speaker:

not reactivity.

Speaker:

With the bodies

Speaker:

in the state of

Speaker:

hyper-reactivity,

Speaker:

when you try to

Speaker:

re-inoculate the

Speaker:

gut, it's not

Speaker:

gonna take hold.

Speaker:

So which means

Speaker:

that all the gram

Speaker:

negative which

Speaker:

are more

Speaker:

anaerobic in

Speaker:

nature are going

Speaker:

to continue to

Speaker:

perpetuate

Speaker:

because the pH is

Speaker:

gonna afford

Speaker:

their continual

Speaker:

activity.

Speaker:

Now, it's very

Speaker:

important.

Speaker:

I love the fact

Speaker:

that you brought

Speaker:

up the microbiome

Speaker:

in the gut

Speaker:

because the

Speaker:

microbiome

Speaker:

expressed 150

Speaker:

times more DNA

Speaker:

than what our

Speaker:

human cells

Speaker:

express.

Speaker:

So their profile

Speaker:

within our bodies

Speaker:

has a direct

Speaker:

impact on our

Speaker:

metabolic

Speaker:

respiratory chain

Speaker:

efficiency, as in

Speaker:

when we have an

Speaker:

excess of

Speaker:

lipopolysaccharides,

Speaker:

given the fact

Speaker:

that they're

Speaker:

anaerobic nature,

Speaker:

can you see how

Speaker:

that can link

Speaker:

into predominance

Speaker:

of glycolysis?

Speaker:

Yes, I can.

Speaker:

Just getting to

Speaker:

feel that

Speaker:

inflammatory

Speaker:

process, yeah.

Speaker:

So it's a

Speaker:

question like,

Speaker:

where do we go

Speaker:

with this?

Speaker:

Like where do we

Speaker:

start in order to

Speaker:

get people

Speaker:

feeling healthy

Speaker:

again and not

Speaker:

having brain fog,

Speaker:

not having

Speaker:

autoimmune

Speaker:

expressions?

Speaker:

Lupus, very

Speaker:

closely and

Speaker:

intimately

Speaker:

connected

Speaker:

to CDR1.

Speaker:

That's the

Speaker:

extremes of CDR1.

Speaker:

We're extremes of

Speaker:

TH2 dominance.

Speaker:

So how do we get

Speaker:

people away from

Speaker:

the potential

Speaker:

expressions of

Speaker:

these

Speaker:

pathological

Speaker:

states?

Speaker:

And it really

Speaker:

comes into seeing

Speaker:

the body from a

Speaker:

holistic

Speaker:

perspective, not

Speaker:

throwing that

Speaker:

word around as

Speaker:

people have, like

Speaker:

really

Speaker:

understanding the

Speaker:

interplay of

Speaker:

multiple

Speaker:

physiological

Speaker:

systems and

Speaker:

specifically

Speaker:

immunometabolism.

Speaker:

See, I didn't, not

Speaker:

metabolimmunism, but

Speaker:

immunometabolism.

Speaker:

And this is, I

Speaker:

feel, not just

Speaker:

feel, but I also

Speaker:

know through

Speaker:

clinical

Speaker:

experience, a way

Speaker:

in which to take

Speaker:

people out of the

Speaker:

state of dorsal,

Speaker:

vagal dominance,

Speaker:

which can also

Speaker:

have an impact,

Speaker:

which does mean,

Speaker:

I mean, there's a

Speaker:

bidirectional

Speaker:

impact on the

Speaker:

nervous system as

Speaker:

well as immune

Speaker:

system,

Speaker:

influencing

Speaker:

physiological

Speaker:

metabolomics.

Speaker:

So the gut, yeah,

Speaker:

if you're damp,

Speaker:

you're gonna have

Speaker:

more elaborate

Speaker:

polysaccharides.

Speaker:

If you're damp,

Speaker:

you're gonna have

Speaker:

more fungi,

Speaker:

meaning more

Speaker:

reoccurring

Speaker:

Candiases.

Speaker:

And everything

Speaker:

that that comes

Speaker:

with as well, I

Speaker:

mean, like just

Speaker:

Candida and its

Speaker:

own, one of the

Speaker:

things that

Speaker:

Candida does, one

Speaker:

of the things, an

Speaker:

increase of

Speaker:

pentociety and

Speaker:

what this does to

Speaker:

the myelin sheath

Speaker:

is quite

Speaker:

destructive,

Speaker:

okay?

Speaker:

Not only does it

Speaker:

induce the

Speaker:

production of

Speaker:

pentociety, which

Speaker:

destroys the

Speaker:

nerve coding,

Speaker:

but also

Speaker:

subsequently

Speaker:

compromises how

Speaker:

well the body can

Speaker:

use arginine and

Speaker:

lysine in

Speaker:

doing so.

Speaker:

And if anybody

Speaker:

knows the

Speaker:

importance of

Speaker:

lysine in terms

Speaker:

of a white blood

Speaker:

selectivity

Speaker:

against viral

Speaker:

threat, when you

Speaker:

compromise that,

Speaker:

what are you

Speaker:

doing to the

Speaker:

adaptive

Speaker:

immune system?

Speaker:

You're tempering

Speaker:

it, not tempering

Speaker:

it, sorry, you

Speaker:

are

Speaker:

compromising it.

Speaker:

So- Yeah, it's

Speaker:

gonna be fairly

Speaker:

dissimated.

Speaker:

Well, the gut is

Speaker:

incredibly

Speaker:

important because

Speaker:

if you're damp

Speaker:

and you've got

Speaker:

Candida, you're

Speaker:

gonna compromise

Speaker:

the adaptive

Speaker:

immune system.

Speaker:

You're gonna

Speaker:

compromise the

Speaker:

liver by way in

Speaker:

which it

Speaker:

increases acetyl

Speaker:

aldehyde

Speaker:

concentration in

Speaker:

the liver, and

Speaker:

subsequently

Speaker:

there by further

Speaker:

compounding

Speaker:

methylation,

Speaker:

not depletion,

Speaker:

but methylation

Speaker:

response,

Speaker:

compromising the

Speaker:

response of

Speaker:

methylation by

Speaker:

way of inhibiting

Speaker:

methionine

Speaker:

synthase, which

Speaker:

is what acetyl

Speaker:

aldehyde does.

Speaker:

So there's so

Speaker:

many sequences of

Speaker:

the gut, but the

Speaker:

gut doesn't one

Speaker:

day wake up and

Speaker:

it's like, okay,

Speaker:

you know, I don't

Speaker:

like you anymore.

Speaker:

Here you go,

Speaker:

enjoy a

Speaker:

shitty life.

Speaker:

Excuse the pun.

Speaker:

(Laughs)

Speaker:

It happens, and

Speaker:

really one needs

Speaker:

to venture into

Speaker:

considering the

Speaker:

Barker

Speaker:

hypothesis.

Speaker:

Within the Barker

Speaker:

hypothesis, it

Speaker:

has been recently

Speaker:

expanded upon.

Speaker:

This Barker

Speaker:

hypothesis was

Speaker:

around, I think

Speaker:

the 60s or so,

Speaker:

and he postulated

Speaker:

the impact of a

Speaker:

lifetime of

Speaker:

exposures to a

Speaker:

person's current

Speaker:

state of health.

Speaker:

And that was

Speaker:

expanded upon in,

Speaker:

I think it was in

Speaker:

2000, or after

Speaker:

2000 and late

Speaker:

90s, in a new

Speaker:

concept, which is

Speaker:

again, just the

Speaker:

evolution of the

Speaker:

Barker hypothesis

Speaker:

and the designs

Speaker:

of health and

Speaker:

disease

Speaker:

hypothesis, which

Speaker:

pretty much looks

Speaker:

at the whole

Speaker:

lifespan as to

Speaker:

how certain

Speaker:

factors may have

Speaker:

influenced the

Speaker:

person's current

Speaker:

state of

Speaker:

microbiome.

Speaker:

And subsequently

Speaker:

what impact that

Speaker:

has on immunology

Speaker:

and so on

Speaker:

and so forth.

Speaker:

So yes, but to

Speaker:

answer your

Speaker:

question, most

Speaker:

certainly a

Speaker:

compromise

Speaker:

gastrointestinal

Speaker:

tract.

Speaker:

I mean, it's the

Speaker:

point of entry

Speaker:

that we have,

Speaker:

it's the most

Speaker:

dramatic point of

Speaker:

entry in terms of

Speaker:

a perceptive

Speaker:

entry that we

Speaker:

have to the

Speaker:

environment.

Speaker:

So yeah, most

Speaker:

certainly it can

Speaker:

induce a

Speaker:

CDR1 state.

Speaker:

It's probably one

Speaker:

of the greater

Speaker:

means in

Speaker:

which to do so.

Speaker:

It's not

Speaker:

the only.

Speaker:

One of the other

Speaker:

ways is actually

Speaker:

by way of simple

Speaker:

things, like

Speaker:

those of you whom

Speaker:

are tattooed, who

Speaker:

have a lot of

Speaker:

tattoos on

Speaker:

the body.

Speaker:

I love tattoos

Speaker:

for the cosmetic

Speaker:

reasons of them,

Speaker:

but they're

Speaker:

really not good

Speaker:

for the

Speaker:

immune system.

Speaker:

They're really

Speaker:

not good for the

Speaker:

immune system

Speaker:

because it

Speaker:

creates a low

Speaker:

grade perpetual

Speaker:

immune activity

Speaker:

based upon the

Speaker:

lead that's in

Speaker:

these tattoos.

Speaker:

And even if you

Speaker:

had lead free

Speaker:

tattoos, there

Speaker:

are other- I was

Speaker:

about to ask.

Speaker:

Yeah, there are

Speaker:

other- 10

Speaker:

minutes.

Speaker:

Puts within them.

Speaker:

They're less

Speaker:

impactful, but

Speaker:

they're still

Speaker:

impactful to

Speaker:

some degree.

Speaker:

So those who have

Speaker:

tattoos, you

Speaker:

should always be

Speaker:

using chlorella.

Speaker:

I'm sorry, you

Speaker:

gotta always use

Speaker:

chlorella and

Speaker:

find a way in

Speaker:

which to preserve

Speaker:

your iron.

Speaker:

Because if you

Speaker:

have a lot of

Speaker:

tattoos and

Speaker:

you're

Speaker:

experiencing

Speaker:

reoccurring

Speaker:

anemia, it ties

Speaker:

into what I

Speaker:

mentioned to you

Speaker:

before about this

Speaker:

perpetual

Speaker:

monocyte

Speaker:

reactivation.

Speaker:

That makes total

Speaker:

sense as well.

Speaker:

Rob, I would love

Speaker:

to do a study.

Speaker:

Maybe one of your

Speaker:

audience can find

Speaker:

a way in which we

Speaker:

can actually do

Speaker:

so efficiently,

Speaker:

whereby we

Speaker:

actually map the

Speaker:

correlation

Speaker:

between those

Speaker:

whom have

Speaker:

tattoos, as well

Speaker:

as the extent or

Speaker:

the timeframe of

Speaker:

chronic viral

Speaker:

expression,

Speaker:

fatigue, chronic

Speaker:

viral expression.

Speaker:

And I'm sure, I

Speaker:

hypothesize that

Speaker:

there is an

Speaker:

intimate,

Speaker:

nobody's done the

Speaker:

study, by

Speaker:

the way.

Speaker:

That's why I'm

Speaker:

putting

Speaker:

out there.

Speaker:

No one's done the

Speaker:

study yet.

Speaker:

No one's done the

Speaker:

study to see what

Speaker:

tattoos, how

Speaker:

tattoos increase

Speaker:

the vulnerability

Speaker:

for post-viral

Speaker:

fatigue.

Speaker:

No one's done the

Speaker:

study yet.

Speaker:

Yeah, no, I don't

Speaker:

think anyone's

Speaker:

ever thought of

Speaker:

doing that study.

Speaker:

It's definitely novel.

Speaker:

I mean, maybe we

Speaker:

would have to get

Speaker:

this in front of

Speaker:

Ben Greenfield,

Speaker:

because he's

Speaker:

definitely

Speaker:

well-to-do and

Speaker:

fairly inked up.

Speaker:

So maybe he's

Speaker:

someone to sort

Speaker:

of talk to.

Speaker:

You've really

Speaker:

alluded to this,

Speaker:

Justin, but I

Speaker:

think it's a

Speaker:

great place to

Speaker:

start ending off.

Speaker:

But just this

Speaker:

idea of the

Speaker:

central nervous

Speaker:

system and its

Speaker:

role in

Speaker:

triggering this

Speaker:

sort of

Speaker:

immunological

Speaker:

metabolic

Speaker:

dysfunction.

Speaker:

Again, me just

Speaker:

taking a sort of

Speaker:

a very layman's

Speaker:

approach to it,

Speaker:

but the idea that

Speaker:

when the nervous

Speaker:

system, when the

Speaker:

body is stressed,

Speaker:

it's not going to

Speaker:

sort of really,

Speaker:

it doesn't, okay,

Speaker:

it does to an

Speaker:

extent, but with

Speaker:

stress is

Speaker:

perceived

Speaker:

as stress.

Speaker:

It doesn't matter

Speaker:

if it's

Speaker:

psychological,

Speaker:

broadly speaking,

Speaker:

or physiological.

Speaker:

You're going to

Speaker:

have the sort of

Speaker:

the same

Speaker:

biological

Speaker:

reactions.

Speaker:

There's going to

Speaker:

be a surge in

Speaker:

catecholamines, a

Speaker:

surge in

Speaker:

hormones.

Speaker:

That's going to

Speaker:

increase the

Speaker:

transcription

Speaker:

factors.

Speaker:

And then you're

Speaker:

going to have

Speaker:

this downstream

Speaker:

effect again on

Speaker:

the immune system

Speaker:

and subsequently

Speaker:

on the metabolism

Speaker:

once again.

Speaker:

And we're going

Speaker:

to end up in this

Speaker:

state of being in

Speaker:

CDR1 two or

Speaker:

three, which I'm

Speaker:

not sure, but I'm

Speaker:

sure you can sort

Speaker:

of elucidate that

Speaker:

more succinctly

Speaker:

than I can.

Speaker:

Do you think that

Speaker:

this theory of,

Speaker:

and I suppose it

Speaker:

ties into some of

Speaker:

Leo Primbok's

Speaker:

work, the

Speaker:

psychoneuroimmunology,

Speaker:

do you think

Speaker:

there is merit to

Speaker:

this idea that a

Speaker:

sort of

Speaker:

psychological

Speaker:

stress in general

Speaker:

can drive this

Speaker:

metabolic

Speaker:

dysfunction?

Speaker:

Or is that sort

Speaker:

of more of an

Speaker:

edge case?

Speaker:

An edge case?

Speaker:

Good question.

Speaker:

I think again, it

Speaker:

is dependent upon

Speaker:

the individual as

Speaker:

to what the

Speaker:

individual had

Speaker:

been exposed to

Speaker:

over a course of

Speaker:

a lifespan.

Speaker:

As an example,

Speaker:

you know, on a

Speaker:

swash leg, I'm

Speaker:

going to use him

Speaker:

as an example,

Speaker:

and he even

Speaker:

discusses this in

Speaker:

a couple of his

Speaker:

documentaries,

Speaker:

whereby his, him

Speaker:

and his brother

Speaker:

were exposed to an

Speaker:

abusive father.

Speaker:

His brother ended

Speaker:

up killing

Speaker:

himself in a car

Speaker:

crash because

Speaker:

whilst he was

Speaker:

drunk, whilst he

Speaker:

was intoxicated.

Speaker:

So, you know, in

Speaker:

two

Speaker:

circumstances,

Speaker:

you have one

Speaker:

person utilizing

Speaker:

that stress for

Speaker:

improvement upon

Speaker:

what adaptability

Speaker:

to some degree,

Speaker:

based upon the

Speaker:

circumstances

Speaker:

he was in.

Speaker:

And the other,

Speaker:

where that stress

Speaker:

overwhelmed him

Speaker:

to the point

Speaker:

where he

Speaker:

pretty much

Speaker:

equated to the

Speaker:

state of

Speaker:

destruction.

Speaker:

So it really,

Speaker:

it's not even a

Speaker:

question of just

Speaker:

genetic.

Speaker:

I mean, for sure,

Speaker:

genetics do play

Speaker:

a role in one's

Speaker:

stress tolerance.

Speaker:

However, what

Speaker:

micron RNA is

Speaker:

being expressed

Speaker:

to put upon

Speaker:

certain sequences

Speaker:

of one's life

Speaker:

experiences will

Speaker:

have also a

Speaker:

greater

Speaker:

determining

Speaker:

epigenetic effect

Speaker:

than just that of

Speaker:

DNA alone.

Speaker:

So yes, is stress

Speaker:

a psychological

Speaker:

stress

Speaker:

contributor

Speaker:

for sure.

Speaker:

But what does

Speaker:

that mean?

Speaker:

I think that's

Speaker:

the question that

Speaker:

you're asking.

Speaker:

What does that

Speaker:

really mean?

Speaker:

Like, how can we

Speaker:

quantify this?

Speaker:

And the truth is,

Speaker:

from an

Speaker:

evidence-based

Speaker:

paradigm, you

Speaker:

can't, you can't,

Speaker:

because then

Speaker:

you've got to

Speaker:

bring it into

Speaker:

reductive models

Speaker:

and create the

Speaker:

ducted reasoning,

Speaker:

which doesn't

Speaker:

take into account

Speaker:

every possible

Speaker:

life experience

Speaker:

that the

Speaker:

individual

Speaker:

has had.

Speaker:

Now, I don't know

Speaker:

two people, even

Speaker:

twins, that have

Speaker:

had the exact

Speaker:

identical life

Speaker:

experiences, or

Speaker:

at least have not

Speaker:

perceived the

Speaker:

exact life

Speaker:

experiences

Speaker:

the same.

Speaker:

I think every

Speaker:

individual,

Speaker:

albeit those who

Speaker:

might be a twin

Speaker:

or not,

Speaker:

experience a life

Speaker:

and a individual

Speaker:

from an

Speaker:

individual

Speaker:

perspective.

Speaker:

So what

Speaker:

does that mean?

Speaker:

And now we are

Speaker:

venturing into

Speaker:

the realm of

Speaker:

metaphysics

Speaker:

again, like what

Speaker:

is consciousness?

Speaker:

What is life?

Speaker:

What does this

Speaker:

all mean?

Speaker:

And like, what do

Speaker:

we mean in our

Speaker:

experience?

Speaker:

Not just what

Speaker:

does that

Speaker:

experience mean

Speaker:

to us, what do we

Speaker:

mean within the

Speaker:

experience?

Speaker:

Like, what is our

Speaker:

essence in

Speaker:

all this?

Speaker:

And I think

Speaker:

regardless of

Speaker:

trying to, once

Speaker:

again, put a

Speaker:

remedy to a

Speaker:

challenge or a scenario

Speaker:

or to a category,

Speaker:

considering

Speaker:

compassionately

Speaker:

the individual

Speaker:

and as to what it

Speaker:

is that they are

Speaker:

reporting, they

Speaker:

are going

Speaker:

through, is

Speaker:

incredibly

Speaker:

important.

Speaker:

Compassion and

Speaker:

cooperation is

Speaker:

the way, I would

Speaker:

love to believe,

Speaker:

is the way of the

Speaker:

future of

Speaker:

medicine.

Speaker:

But in order for

Speaker:

that to come into

Speaker:

complete

Speaker:

fruition, we need

Speaker:

to change the way

Speaker:

in which we

Speaker:

perceive or how

Speaker:

we perceive

Speaker:

others, let alone

Speaker:

how we perceive

Speaker:

ourselves.

Speaker:

I mean, we first

Speaker:

can change how we

Speaker:

perceive

Speaker:

ourselves.

Speaker:

That in its own

Speaker:

right is a rite

Speaker:

of passage, which

Speaker:

I think takes

Speaker:

multiple

Speaker:

lifetimes to do,

Speaker:

in all honesty,

Speaker:

but there's no

Speaker:

reason as to why

Speaker:

we cannot

Speaker:

simultaneously at

Speaker:

least attempt and

Speaker:

try to change our

Speaker:

perception

Speaker:

of others.

Speaker:

And also again,

Speaker:

just venturing

Speaker:

into the

Speaker:

metaphysics here,

Speaker:

again, Professor

Speaker:

Hugh Limb as a

Speaker:

professor who was

Speaker:

treating the

Speaker:

medically, sorry,

Speaker:

the criminally

Speaker:

insane in Hawaii,

Speaker:

and he adopted

Speaker:

this Hawaiian

Speaker:

prayer called

Speaker:

"Upon O'Pono."

Speaker:

And there's a lot

Speaker:

of obviously

Speaker:

rumor around what

Speaker:

it had or had not

Speaker:

done, but by his

Speaker:

own account, he

Speaker:

was able to heal

Speaker:

the criminally

Speaker:

insane by way of

Speaker:

changing his

Speaker:

perception

Speaker:

through this

Speaker:

prayer of what it

Speaker:

is that he

Speaker:

believed these

Speaker:

people to be.

Speaker:

And perhaps that

Speaker:

also ventures

Speaker:

into yet another

Speaker:

question is that

Speaker:

are those we deem

Speaker:

to be faulty, are

Speaker:

those who we deem

Speaker:

to be faulty the

Speaker:

construct of our

Speaker:

ego, trying to

Speaker:

have them fit

Speaker:

into a narrative

Speaker:

of our own

Speaker:

design, or is the

Speaker:

construct of our

Speaker:

ego and the

Speaker:

narrative of our

Speaker:

own design the

Speaker:

problem

Speaker:

over here?

Speaker:

And I'm inclined

Speaker:

to believe that

Speaker:

egoic and

Speaker:

identity of which

Speaker:

the majority of

Speaker:

humanity has

Speaker:

adopted over

Speaker:

throughout its

Speaker:

incarnation,

Speaker:

really is at

Speaker:

fault in that we

Speaker:

have lost, and

Speaker:

I'm hoping that

Speaker:

we can reemerge

Speaker:

the compassionate

Speaker:

understanding of

Speaker:

our fellow man

Speaker:

and what they're

Speaker:

going through.

Speaker:

Because truly

Speaker:

it's only through

Speaker:

understanding

Speaker:

that we can

Speaker:

cultivate

Speaker:

patience to see,

Speaker:

okay, like the

Speaker:

psychology, what

Speaker:

this person is

Speaker:

experiencing

Speaker:

might be trivial

Speaker:

to you or to me

Speaker:

or to somebody

Speaker:

else, but to that

Speaker:

person it's

Speaker:

detrimental,

Speaker:

okay?

Speaker:

It's relative.

Speaker:

Yeah, exactly,

Speaker:

it's relative,

Speaker:

incredibly

Speaker:

relative.

Speaker:

And bringing it

Speaker:

back to the

Speaker:

theory of

Speaker:

relativity here,

Speaker:

(Laughs)

Speaker:

and the

Speaker:

perspective

Speaker:

influence that

Speaker:

that has on life

Speaker:

and the speed of

Speaker:

life and

Speaker:

everything that

Speaker:

that can have

Speaker:

from a

Speaker:

perspective of

Speaker:

physics,

Speaker:

biophysics

Speaker:

in the body,

Speaker:

relative

Speaker:

perspective most

Speaker:

certainly has an

Speaker:

impact on

Speaker:

biophysics,

Speaker:

undoubtedly.

Speaker:

And there are

Speaker:

actually some

Speaker:

documented

Speaker:

studies of this

Speaker:

matter as well.

Speaker:

And there is the

Speaker:

Institute of

Speaker:

Noetic Sciences

Speaker:

that was founded

Speaker:

by an astronaut,

Speaker:

his name is Dr.

Speaker:

Edgar Mitchell,

Speaker:

of which they

Speaker:

actually mapped

Speaker:

out

Speaker:

scientifically

Speaker:

the impact of

Speaker:

relative

Speaker:

consciousness to

Speaker:

biophysics, the

Speaker:

movement of

Speaker:

particles in the

Speaker:

body itself.

Speaker:

So it's, yes, to

Speaker:

answer your

Speaker:

question, most

Speaker:

certainly it can

Speaker:

lead into a CDR1,

Speaker:

but as to what

Speaker:

measure that, as

Speaker:

to what point

Speaker:

within a measure

Speaker:

it could induce

Speaker:

that is variable

Speaker:

to the

Speaker:

individual.

Speaker:

It is not a set

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standard, it's

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not a set

Speaker:

universal

Speaker:

standard that

Speaker:

everybody would

Speaker:

be

Speaker:

susceptible to.

Speaker:

There's a varying

Speaker:

degree of

Speaker:

susceptibility

Speaker:

across the board.

Speaker:

Yeah, it would

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probably require

Speaker:

a bit more than

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sort of an HRV

Speaker:

intervention, I'd

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imagine to sort

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of try and

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ascertain that

Speaker:

level of data.

Speaker:

Justin, I think,

Speaker:

to be honest,

Speaker:

we've been going

Speaker:

on for nearly

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three hours.

Speaker:

(Laughs) So what I'd love

Speaker:

to- Are you

Speaker:

kidding me?

Speaker:

Wow, this is

Speaker:

incredible,

Speaker:

fantastic, good.

Speaker:

It's been

Speaker:

absolutely

Speaker:

amazing,

Speaker:

thank you.

Speaker:

To end off with,

Speaker:

I'd love to ask

Speaker:

you a few rapid

Speaker:

fire questions,

Speaker:

and then, yeah,

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let's call it a

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day, and we can

Speaker:

then point people

Speaker:

to where they can

Speaker:

find you.

Speaker:

But to start off

Speaker:

with, what do you

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think is the most

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underrated

Speaker:

nutrient from an

Speaker:

immunological

Speaker:

health

Speaker:

standpoint?

Speaker:

Most underrated

Speaker:

nutrient.

Speaker:

I know we had

Speaker:

discussed this

Speaker:

briefly before,

Speaker:

and I wrote

Speaker:

garlic, but I'm

Speaker:

not sure.

Speaker:

It's a really

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difficult

Speaker:

question

Speaker:

to answer.

Speaker:

Within the

Speaker:

context of CDR1,

Speaker:

or in the context

Speaker:

of, in what

Speaker:

context?

Speaker:

Let me ask you

Speaker:

that, let me ask

Speaker:

your question to

Speaker:

your question, in

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what context?

Speaker:

Okay.

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Let's go with,

Speaker:

yeah, let's go

Speaker:

with CDR1.

Speaker:

It's what we've

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discussed most

Speaker:

today, I think,

Speaker:

so it's probably

Speaker:

most relevant.

Speaker:

Contextual,

Speaker:

because CDR1 has

Speaker:

many contributory

Speaker:

factors to it.

Speaker:

So I'm gonna go

Speaker:

through those

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factors, and then

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I'll give you

Speaker:

some indication.

Speaker:

So if it's a

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question of

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compromised

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histamine

Speaker:

intolerance in

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terms of a

Speaker:

dietary histamine

Speaker:

intolerance,

Speaker:

those whom are

Speaker:

able to

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metabolize

Speaker:

sulfur, onion, I

Speaker:

mean, works

Speaker:

incredibly well,

Speaker:

has a natural

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source of

Speaker:

kerstin, and

Speaker:

kerstin is the

Speaker:

molecule, the

Speaker:

nutrient in

Speaker:

question, that

Speaker:

helps a lot with

Speaker:

modulating the

Speaker:

mast cells.

Speaker:

If it's a

Speaker:

question of

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estrogen

Speaker:

dominance that

Speaker:

might be fueling

Speaker:

the histamine, or

Speaker:

perpetuating the

Speaker:

histamine

Speaker:

response, then

Speaker:

broccoli and

Speaker:

subsequent indole

Speaker:

methane also

Speaker:

support the

Speaker:

modulation to the

Speaker:

CDR1 response.

Speaker:

If it's a

Speaker:

question of

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prostate gladdon

Speaker:

imbalance, I'm

Speaker:

not a big fan of

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fish roll, but I

Speaker:

am a big fan of

Speaker:

perzolving

Speaker:

mediators.

Speaker:

Perzolving

Speaker:

mediators.

Speaker:

Yeah, so that

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there is a great,

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if there's an

Speaker:

imbalance of

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lipid utility,

Speaker:

that would be a

Speaker:

place to start.

Speaker:

If there's

Speaker:

imbalance of

Speaker:

methylation

Speaker:

imbalance, then

Speaker:

determining

Speaker:

exactly whether

Speaker:

or not, if it's a

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beta oxidative

Speaker:

issue, then

Speaker:

pantothenin can

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work

Speaker:

incredibly well.

Speaker:

If it's a pyrol

Speaker:

issue, then

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pyrolyloxin can

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work really well.

Speaker:

If it is a

Speaker:

question of poor

Speaker:

glutathione

Speaker:

recycling and

Speaker:

your GSSG levels

Speaker:

being higher,

Speaker:

then rubber

Speaker:

flabbing can work

Speaker:

incredibly well.

Speaker:

I think I gave

Speaker:

enough examples.

Speaker:

I think so.

Speaker:

You answered that

Speaker:

as only an

Speaker:

academic could,

Speaker:

is that already

Speaker:

possible?

Speaker:

Yeah, it's a

Speaker:

broad question.

Speaker:

It's like, you

Speaker:

know, within,

Speaker:

even in the

Speaker:

subject of CDR1

Speaker:

or TH2 dominance,

Speaker:

what, you know,

Speaker:

there's so many

Speaker:

contradictory

Speaker:

factors that can

Speaker:

have an influence

Speaker:

on that.

Speaker:

Like, one can

Speaker:

even venture into

Speaker:

amino acids now,

Speaker:

like theanine, to

Speaker:

prove a polygonal

Speaker:

response, and

Speaker:

thereby hopefully

Speaker:

mitigating

Speaker:

glutamate

Speaker:

dominance, which

Speaker:

also by way,

Speaker:

influences CDR1

Speaker:

expression,

Speaker:

glutamate

Speaker:

dominance.

Speaker:

So yeah, which, like

Speaker:

polysaccharides

Speaker:

have an influence

Speaker:

on activating

Speaker:

NMDA receptors,

Speaker:

which are one of

Speaker:

the subsets of,

Speaker:

there's two

Speaker:

classes of

Speaker:

glutamate

Speaker:

receptors.

Speaker:

It's one of the

Speaker:

subsets of the

Speaker:

main class of

Speaker:

glutamate

Speaker:

receptors.

Speaker:

So, you know,

Speaker:

theanine, green

Speaker:

tea, could have

Speaker:

sort of

Speaker:

contextual

Speaker:

importance

Speaker:

as well.

Speaker:

That's

Speaker:

incredible,

Speaker:

thank you.

Speaker:

Okay, next one.

Speaker:

What's one

Speaker:

supplement you

Speaker:

personally could

Speaker:

not go without?

Speaker:

Again, another

Speaker:

contextual

Speaker:

question.

Speaker:

Can I not go

Speaker:

within which,

Speaker:

within which

Speaker:

scenario?

Speaker:

Just generally,

Speaker:

if you got stuck

Speaker:

in a desert

Speaker:

island with one

Speaker:

bottle of

Speaker:

something.

Speaker:

Yeah, my friend

Speaker:

Dominic

Speaker:

Nischwitz, he

Speaker:

told me to say

Speaker:

chlorella.

Speaker:

(Laughing)

Speaker:

I'm sorry for it.

Speaker:

Chlorella,

Speaker:

chlorella.

Speaker:

Which is right, I

Speaker:

think chlorella

Speaker:

is incredible

Speaker:

compound.

Speaker:

Amazing, so many,

Speaker:

it's got a great

Speaker:

source of iodine,

Speaker:

great binder,

Speaker:

great B vitamin

Speaker:

profile, great

Speaker:

selenium profile,

Speaker:

really is a

Speaker:

super sweet.

Speaker:

Supplement, could

Speaker:

I not go without?

Speaker:

You've got

Speaker:

phosphatidylcholine

Speaker:

here, I

Speaker:

think, PC.

Speaker:

Yeah, I think in

Speaker:

my particular

Speaker:

case, having

Speaker:

historically

Speaker:

having had issues

Speaker:

with bioacid

Speaker:

activity,

Speaker:

and also

Speaker:

subsequent

Speaker:

certain cognitive

Speaker:

memory recall

Speaker:

issues, certain

Speaker:

points when I had

Speaker:

my water

Speaker:

immunity,

Speaker:

phosphatidylcholine

Speaker:

was certainly

Speaker:

mitigated a lot

Speaker:

of this.

Speaker:

So

Speaker:

phosphatidylcholine

Speaker:

is different, be

Speaker:

on the top

Speaker:

of the list.

Speaker:

And I also do

Speaker:

have certain PEMT

Speaker:

genome that makes

Speaker:

me more

Speaker:

vulnerable to

Speaker:

deficiency of

Speaker:

cholera,

Speaker:

phosphatidylcholine.

Speaker:

So let's go with

Speaker:

that one, let's

Speaker:

go with that one.

Speaker:

Okay, perfect.

Speaker:

Emerging therapies you're

Speaker:

most excited

Speaker:

about or therapy?

Speaker:

I always forget

Speaker:

how, because I

Speaker:

always wanted to

Speaker:

say

Speaker:

ionotrophysis,

Speaker:

but it's not how

Speaker:

you, it's

Speaker:

ionophoresis.

Speaker:

That was Newton,

Speaker:

I must admit.

Speaker:

Yeah, it's quite

Speaker:

an interesting

Speaker:

technology,

Speaker:

almost works like

Speaker:

on a battery type

Speaker:

of a dark man

Speaker:

concept in terms

Speaker:

of the positive

Speaker:

and

Speaker:

negative charge.

Speaker:

And what it does

Speaker:

by inducing this

Speaker:

ionic

Speaker:

displacement, it

Speaker:

opens up the

Speaker:

membranes to be

Speaker:

more accepting of

Speaker:

nutrient

Speaker:

delivery.

Speaker:

So it's quite an

Speaker:

interesting

Speaker:

model.

Speaker:

There's a few

Speaker:

companies, Ion

Speaker:

Layer, and there

Speaker:

are others as

Speaker:

well, that

Speaker:

provide this

Speaker:

technology by way

Speaker:

of delivering NAD

Speaker:

and glutathione.

Speaker:

Molecules that

Speaker:

are highly

Speaker:

susceptible to

Speaker:

the gastric

Speaker:

environment as an

Speaker:

example.

Speaker:

So it's quite

Speaker:

cool, I'm working

Speaker:

with a scientist,

Speaker:

his name's also

Speaker:

Justin, Justin

Speaker:

Kirkland,

Speaker:

incredible mind.

Speaker:

He's got some

Speaker:

real cool

Speaker:

innovative

Speaker:

technologies that

Speaker:

he's busy with at

Speaker:

the moment.

Speaker:

And I'm hopeful

Speaker:

that in due

Speaker:

course, majority

Speaker:

of the nutrients

Speaker:

that we prescribe

Speaker:

within our

Speaker:

practice can

Speaker:

actually be given

Speaker:

by way of patch

Speaker:

delivery rather

Speaker:

than

Speaker:

ingesting it.

Speaker:

Obviously, albeit

Speaker:

things like

Speaker:

lipids, I think

Speaker:

it would be more

Speaker:

difficult to do.

Speaker:

And the larger

Speaker:

particles might

Speaker:

be a little bit

Speaker:

more challenging.

Speaker:

Binders, we're

Speaker:

certainly gonna

Speaker:

wanna ingest for

Speaker:

the purpose of

Speaker:

the need to

Speaker:

buy toxins.

Speaker:

But yeah, I think

Speaker:

it's an

Speaker:

interesting tech

Speaker:

because it does

Speaker:

pave the way and

Speaker:

the potential for

Speaker:

not to have to

Speaker:

consume so many

Speaker:

pills, so many

Speaker:

capsules and

Speaker:

supplements,

Speaker:

whilst still

Speaker:

getting the

Speaker:

benefit in the

Speaker:

increase of

Speaker:

biological

Speaker:

availability.

Speaker:

Yeah, no, that's

Speaker:

an interesting

Speaker:

one and one I'll

Speaker:

definitely be

Speaker:

exploring.

Speaker:

Okay, let's end

Speaker:

off with one

Speaker:

about the gut.

Speaker:

What's the

Speaker:

biggest myth

Speaker:

about gut health

Speaker:

that you

Speaker:

regularly

Speaker:

encounter?

Speaker:

It must be, it

Speaker:

must certainly

Speaker:

must have to do

Speaker:

with fermented

Speaker:

fruits,

Speaker:

fermented fruits.

Speaker:

People have this

Speaker:

being told, I

Speaker:

mean, it's only

Speaker:

natural.

Speaker:

Every time you,

Speaker:

well, when you

Speaker:

used to look at

Speaker:

least in social

Speaker:

media, it was all

Speaker:

about kimchi and

Speaker:

sauerkrauts and

Speaker:

kefir and

Speaker:

everything else.

Speaker:

Now I'm not

Speaker:

saying these are

Speaker:

bad, they come

Speaker:

textual again.

Speaker:

But particularly

Speaker:

in a TH2 dominant

Speaker:

state, you do not

Speaker:

wanna be

Speaker:

consuming a lot

Speaker:

of these foods

Speaker:

because by nature

Speaker:

of them being

Speaker:

fermented,

Speaker:

they're gonna

Speaker:

have a high

Speaker:

histamine blow.

Speaker:

Okay, so it's

Speaker:

really like, it's

Speaker:

such a myth like,

Speaker:

eat more

Speaker:

sauerkraut and

Speaker:

you're gonna have

Speaker:

healthy

Speaker:

microbiome or

Speaker:

drink more kefir

Speaker:

and you're gonna

Speaker:

have healthy

Speaker:

microbiome.

Speaker:

Or if you have

Speaker:

stomach issues,

Speaker:

please drink

Speaker:

more kefir.

Speaker:

No, like if you

Speaker:

have stomach

Speaker:

issues that it's

Speaker:

been instigated

Speaker:

by muscle

Speaker:

activation

Speaker:

syndrome, please

Speaker:

do not drink more

Speaker:

fucking kefir.

Speaker:

Flipping,

Speaker:

flipping,

Speaker:

kefir, kanao.

Speaker:

Like this, yeah,

Speaker:

just a context, a

Speaker:

context, content

Speaker:

and context.

Speaker:

Yeah, Justin,

Speaker:

those are perfect

Speaker:

answers.

Speaker:

Thank you again.

Speaker:

Answered only as

Speaker:

an

Speaker:

academic could.

Speaker:

I've said this

Speaker:

once before, that

Speaker:

was to Tyler

Speaker:

Pansner, but I

Speaker:

think I might be

Speaker:

in love with

Speaker:

your brain.

Speaker:

I really can't

Speaker:

thank you enough

Speaker:

for your time.

Speaker:

You've already

Speaker:

alluded to

Speaker:

autonomic

Speaker:

coaching, but

Speaker:

where can people

Speaker:

find you if

Speaker:

they'd like to

Speaker:

connect?

Speaker:

Instagram

Speaker:

autonomic_coaching

Speaker:

through our

Speaker:

website,

Speaker:

www.autonomiccoaching.com.

Speaker:

Else you can drop

Speaker:

us an email, info

Speaker:

at

Speaker:

autonomiccoaching.com.

Speaker:

Do keep an eye

Speaker:

out for my book

Speaker:

that is gonna be

Speaker:

provisionally

Speaker:

going to be

Speaker:

launched at the

Speaker:

end of September.

Speaker:

And within that,

Speaker:

there'll be even

Speaker:

more details as

Speaker:

to how you can

Speaker:

connect with us.

Speaker:

That's perfect,

Speaker:

and we'll be

Speaker:

short-linked to

Speaker:

all of that in

Speaker:

the show notes.

Speaker:

Justin, thank you

Speaker:

so much for

Speaker:

your time.

Speaker:

Thank you, Rob.

Speaker:

Take care.